SRRA Insider Trading - Sierra Oncology Inc

Insider-Aktien

7.464.864 shares

Insider-Stimmungswert

Der Insider-Stimmungswert ermittelt die Unternehmen, die von Unternehmensinsidern gekauft werden.

Es ist das Ergebnis eines ausgeklügelten quantitativen Multifaktormodells, das die Unternehmen mit der höchsten Insiderakkumulation identifiziert. Das Scoring-Modell verwendet eine Kombination aus der Nettozahl der Insiderkäufe der letzten 90 Tage, der Gesamtzahl der gekauften Aktien als Prozentsatz des Streubesitzes und der Gesamtzahl der von Insidern gehaltenen Aktien. Die Zahl reicht von 0 bis 100, wobei höhere Zahlen ein höheres Maß an Insiderkäufen anzeigen als bei anderen Unternehmen und 50 den Durchschnitt darstellt.

Aktualisierungshäufigkeit: Täglich

Sehen Sie sich die Top-Optionen der Insider an, die eine Liste der Unternehmen mit der höchsten Insiderakkumulation enthalten.

Siehe Aktien mit dem höchsten Ranking

Führungskräfte-Stimmungswert

Der Führungskräfte-Stimmungswert findet Unternehmen, die von Führungskräften des Unternehmens gekauft werden.

Per Definition sind Führungskräfte des Unternehmens Insider, aber im Gegensatz zu anderen Insidern (10%ige Aktionäre und Vorstandsmitglieder) arbeiten Führungskräfte täglich für das Unternehmen und verwenden beim Handel ihr eigenes Geld. (10%ige Aktionäre und Vorstandsmitglieder sind oft Fondsmanager, die das Geld anderer Leute verwalten.) Daher sind Insider-Geschäfte, die von Führungskräften getätigt werden, viel bedeutender und sollten entsprechend behandelt werden.

Wie der Insider-Stimmungswert ist auch der Führungskräfte-Stimmungswert das Ergebnis eines ausgeklügelten quantitativen Multifaktormodells, das die Unternehmen mit der höchsten Führungskräftekonzentration identifiziert.

Aktualisierungshäufigkeit: Täglich

Sehen Sie sich die Insiders Top-Auswahl an, die eine Liste der Unternehmen mit der höchsten Insider-Stimmung enthalten.

Siehe Aktien mit dem höchsten Ranking

Wichtige Insider-Kennzahlen

Diese Karte zeigt, wie das Unternehmen bei verschiedenen Insider-Kennzahlen abschneidet. Der Perzentil-Rang zeigt, wie dieses Unternehmen im Vergleich zu anderen Unternehmen auf den US-Märkten abschneidet. Höhere Ränge deuten auf eine bessere Situation hin.

Es ist beispielsweise allgemein anerkannt, dass Insiderkäufe ein positiver Indikator sind, so dass Unternehmen mit mehr Insiderkäufen besser abschneiden würden als Unternehmen mit weniger Insiderkäufen (oder sogar Insiderverkäufen).

Nettoanzahl der Insider, die kaufen (Rang)

N/A

Die Nettoanzahl der Insiderkäufe ist die Gesamtzahl der Insiderkäufe abzüglich der Gesamtzahl der Insiderverkäufe in den letzten 90 Tagen. Der Perzentilrang wird hier angezeigt (Bereich von 0 bis 100%).

Prozent des Streubesitzes von Insidern gekauft (Rang)

N/A

Prozent des von Insidern gekauften Streubesitzes ist die Gesamtzahl der von Insidern gekauften Aktien abzüglich der Gesamtzahl der von Insidern in den letzten 90 Tagen verkauften Aktien, geteilt durch den gesamten Streubesitz und multipliziert mit 100.

Diagramm zum Insiderhandel

Sierra Oncology Inc Insider-Trades sind in der folgenden Grafik dargestellt. Insider sind leitende Angestellte, Direktoren oder bedeutende Investoren in einem Unternehmen. Im Allgemeinen ist es für Insider illegal, auf der Grundlage von wesentlichen, nicht-öffentlichen Informationen mit Aktien ihrer Unternehmen zu handeln. Das bedeutet nicht, dass es für sie illegal ist, irgendwelche Geschäfte in ihren eigenen Unternehmen zu tätigen. Sie müssen jedoch alle Geschäfte der SEC über ein Formular 4 melden.

Kennzahlen zu Insiderlisten und Rentabilität

Diese Tabelle zeigt die Liste der bekannten Insider und wird automatisch aus den bei der SEC eingereichten Unterlagen erstellt. Zusätzlich zu den Namen, dem letzten Titel und der Bezeichnung als Direktor, leitender Angestellter oder 10%-iger Anteilseigner geben wir die zuletzt veröffentlichten Bestände an. Zusätzlich stellen wir, wenn möglich, die historische Handelsperformance für den Insider zur Verfügung. Die historische Handelsperformance ist ein gewichteter Durchschnitt der Performance tatsächlicher offener Kauftransaktionen, die von dem Insider getätigt wurden. Weitere Informationen zur Berechnung dieses Wertes finden Sie in diesem YouTube-Webinar.

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Insider	Durchschnittlicher Gewinn (%)	Aktien in Besitz	Split Angepasst

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Erfolgsbilanz der Insiderkäufe - Kurzfristige Gewinnanalyse

In diesem Abschnitt analysieren wir die Rentabilität jedes ungeplanten Insiderkaufs, der auf dem freien Markt in SRRA / Sierra Oncology Inc getätigt wurde. Diese Analyse hilft zu verstehen, ob der Insider beständig abnormale Renditen erzielt und es sich lohnt, ihm zu folgen. Diese Analyse bezieht sich auf ein Jahr nach jedem Handel, und die Ergebnisse sind theoretisch .

Die folgende Tabelle zeigt die jüngsten Käufe am offenen Markt, die nicht Teil eines automatischen Handelsplans waren.

Handelsdatum	Insider	Gemeldete Aktien	Gemeldeter Preis	Angepasste Aktien	Angepasster Preis	Kostenbasis	Tage bis Max	Preis bei Max	Max Gewinn ($)	Max Rendite (%)
2022-02-02	Longitude Capital Partners III, LLC	175.000	27,0000	175.000	27,0000	4.725.000	148	54.9900	4.898.250	103,67
2022-01-31	Vivo Opportunity, LLC	800.000	27,0000	800.000	27,0000	21.600.000
2022-01-31	Abingworth LLP	150.000	27,0000	150.000	27,0000	4.050.000
2021-11-24	Collard Craig A	7.899	23,0850	7.899	23,0850	182.348
2021-11-23	Collard Craig A	5.601	22,9450	5.601	22,9450	128.515
2021-05-19	DILLY STEPHEN GEORGE	5.000	17,8300	5.000	17,8300	89.150
2020-08-18	Klencke Barbara	5.950	12,2201	5.950	12,2201	72.710
2020-08-18	Klencke Barbara	3.325	12,2519	3.325	12,2519	40.738
2019-08-23	Klencke Barbara	108.000	0,4387	2.700	17,5480	47.380

Bereinigter Preis ist der splitbereinigte Preis. Bereinigte Aktien sind die um den Split bereinigten Aktien.

SRRA / Sierra Oncology Inc Insider Trades

Erfolgsbilanz von Insiderverkäufen - Kurzfristige Verlustanalyse

In diesem Abschnitt analysieren wir die kurzfristige Verlustvermeidung jedes ungeplanten Insider-Verkaufs auf dem freien Markt in SRRA / Sierra Oncology Inc. Ein konsistentes Muster der Verlustvermeidung kann darauf hindeuten, dass zukünftige Verkaufstransaktionen Kursrückgänge vorhersagen können. Diese Analyse bezieht sich auf ein Jahr nach jedem Handel, und die Ergebnisse sind theoretisch .

Die folgende Tabelle zeigt die jüngsten Verkäufe am offenen Markt, die nicht Teil eines automatischen Handelsplans waren.

Handelsdatum	Insider	Gemeldete Aktien	Gemeldeter Preis	Angepasste Aktien	Angepasster Preis	Kostenbasis	Tage bis Min	Preis bei Min	Max Verlust Vermieden($)	Max Verlust Vermieden(%)
Es sind keine ungeplanten Open-Market-Trades für diesen Insider bekannt

Bereinigter Preis ist der splitbereinigte Preis. Bereinigte Aktien sind die um den Split bereinigten Aktien.

Transaktionshistorie

Klicken Sie auf das Link-Symbol, um den vollständigen Transaktionsverlauf anzuzeigen. Transaktionen, die im Rahmen eines automatischen Handelsplans 10b5-1 gemeldet werden, sind in der Spalte 10b-5 mit einem X gekennzeichnet.

Datei Datum	Handel Datum	Form	Insider	Ticker	Wertpapier-Titel	Code	Direkt	Ausführung Preis	Einheit Preis	Eimheiten Verändert	Wert Geändert (1K)	Verbleibende Optionen	Verbleibende Aktien
2022-07-01	2022-07-01	4	Vivo Opportunity, LLC By: Vivo Capital Fund IX, L.P.	SRRA	Common Stock	D - Sale to Issuer	I		55,0000	-431.947	-23.757		0
2022-07-01	2022-07-01	4	Vivo Opportunity, LLC By: Vivo Opportunity Fund Holdings, L.P.	SRRA	Common Stock	D - Sale to Issuer	I		55,0000	-2.735.853	-150.472		0
2022-07-01	2022-07-01	4	Vivo Opportunity, LLC By: Vivo Ventures Fund VII, L.P. and Vivo Ventures VII Affiliates Fund, L.P.	SRRA	Common Stock	D - Sale to Issuer	I		55,0000	-161.712	-8.894		0
2022-07-01	2022-07-01	4	ORBIMED ADVISORS LLC See footnotes	SRRA	Common Stock	D - Sale to Issuer	I		55,0000	-226.704	-12.469		0
2022-07-01	2022-07-01	4	ORBIMED ADVISORS LLC See footnotes	SRRA	Common Stock	D - Sale to Issuer	I		55,0000	-226.704	-12.469		0
2022-07-01	2022-07-01	4	ORBIMED ADVISORS LLC See footnotes	SRRA	Common Stock	D - Sale to Issuer	I		55,0000	-1.511.362	-83.125		0
2022-07-01	2022-07-01	4	Ashiya Mona See footnotes	SRRA	Common Stock	D - Sale to Issuer	I		55,0000	-226.704	-12.469		0
2022-07-01	2022-07-01	4	Ashiya Mona See footnotes	SRRA	Common Stock	D - Sale to Issuer	I		55,0000	-226.704	-12.469		0
2022-07-01	2022-07-01	4	Ashiya Mona See footnotes	SRRA	Common Stock	D - Sale to Issuer	I		55,0000	-1.511.362	-83.125		0
2022-07-01	2022-07-01	4	Aggarwal Gaurav By: Vivo Opportunity Fund Holdings, L.P.	SRRA	Common Stock	D - Sale to Issuer	I		55,0000	-2.735.853	-150.472		0
2022-07-01	2022-07-01	4	Klencke Barbara By spouse	SRRA	Common Stock	D - Sale to Issuer	I		55,0000	-5.000	-275		0
2022-07-01	2022-07-01	4	Klencke Barbara	SRRA	Common Stock	D - Sale to Issuer	D		55,0000	-10.000	-550		0
2022-07-01	2022-07-01	4	Sinclair Andrew See footnotes	SRRA	Common Stock, $0.001 par value	D - Sale to Issuer	I		55,0000	-1.314.127	-72.277		0
2022-07-01	2022-07-01	4	Allen Andrew R	SRRA	Common Stock	D - Sale to Issuer	D		55,0000	-1.650	-91		0
2022-07-01	2022-07-01	4	Collard Craig A	SRRA	Common Stock	D - Sale to Issuer	D		55,0000	-13.500	-742		0
2022-07-01	2022-07-01	4	DILLY STEPHEN GEORGE	SRRA	Common Stock	D - Sale to Issuer	D		55,0000	-5.000	-275		0
2022-04-29	2022-04-27	4	Longitude Capital Partners III, LLC	SRRA	Common Stock	J - Other	I			840			8.015
2022-04-29	2022-04-27	4	Longitude Capital Partners III, LLC	SRRA	Common Stock	J - Other	I			252			2.404
2022-04-29	2022-04-27	4	Longitude Capital Partners III, LLC	SRRA	Common Stock	J - Other	I			588			5.611
2022-04-29	2022-04-27	4	Longitude Capital Partners III, LLC	SRRA	Common Stock	J - Other	I			7.175			7.175
2022-04-29	2022-04-27	4	Longitude Capital Partners III, LLC	SRRA	Common Stock	J - Other	I			2.152			2.152
2022-04-29	2022-04-27	4	Longitude Capital Partners III, LLC	SRRA	Common Stock	J - Other	I			5.023			5.023
2022-04-29	2022-04-27	4	Longitude Capital Partners III, LLC	SRRA	Common Stock	J - Other	I			-1.964.771			0
2022-04-29	2022-04-27	4	Longitude Capital Partners III, LLC	SRRA	Common Stock	J - Other	I			-175.000			0
2022-04-07	2022-04-06	4	Turner William D.	SRRA	Stock Option (Right to Buy)	M - Exercise	D	12,05		6.347		0
2022-04-07	2022-04-06	4	Turner William D.	SRRA	Common Stock	S - Sale	D		37,2474	-6.347	-236		0
2022-04-07	2022-04-06	4	Turner William D.	SRRA	Common Stock	M - Exercise	D		12,0500	6.347	76		6.347
2022-04-07	2022-04-05	4	Turner William D.	SRRA	Stock Option (Right to Buy)	M - Exercise	D	12,05		100		0
2022-04-07	2022-04-05	4	Turner William D.	SRRA	Common Stock	S - Sale	D		37,0900	-100	-4		0
2022-04-07	2022-04-05	4	Turner William D.	SRRA	Common Stock	M - Exercise	D		12,0500	100	1		100
2022-04-04	2022-04-04	4	Thomson Mary Christina	SRRA	Stock Option (Right to Buy)	M - Exercise	D	13,04		2.000		0
2022-04-04	2022-04-04	4	Thomson Mary Christina	SRRA	Common Stock	S - Sale	D		35,1384	-2.000	-70		0
2022-04-04	2022-04-04	4	Thomson Mary Christina	SRRA	Common Stock	M - Exercise	D		13,0400	2.000	26		2.000
2022-03-22	2022-03-18	4	Turner William D.	SRRA	Stock Option (Right to Buy)	M - Exercise	D	12,05		100		0
2022-03-22	2022-03-18	4	Turner William D.	SRRA	Common Stock	S - Sale	D		37,0500	-100	-4		0
2022-03-22	2022-03-18	4	Turner William D.	SRRA	Common Stock	M - Exercise	D		12,0500	100	1		100
2022-03-17	2022-03-17	4	Turner William D.	SRRA	Stock Option (Right to Buy)	M - Exercise	D	12,05		3.453		0
2022-03-17	2022-03-17	4	Turner William D.	SRRA	Common Stock	S - Sale	D		37,0558	-3.453	-128		0
2022-03-17	2022-03-17	4	Turner William D.	SRRA	Common Stock	M - Exercise	D		12,0500	3.453	42		3.453
2022-03-14	2022-03-14	4	DILLY STEPHEN GEORGE	SRRA	Stock Option (Right to Buy)	A - Award	D	31,54		165.000		165.000
2022-03-14	2022-03-14	4	Jagpal Sukhi	SRRA	Stock Option (Right to Buy)	A - Award	D	31,54		50.000		50.000
2022-03-14	2022-03-14	4	Klencke Barbara	SRRA	Stock Option (Right to Buy)	A - Award	D	31,54		50.000		50.000
2022-03-14	2022-03-14	4	Norrett Kevin	SRRA	Stock Option (Right to Buy)	A - Award	D	31,54		35.000		35.000
2022-03-14	2022-03-14	4	Turner William D.	SRRA	Stock Option (Right to Buy)	A - Award	D	31,54		35.000		35.000
2022-03-14	2022-03-14	4	Thomson Mary Christina	SRRA	Stock Option (Right to Buy)	A - Award	D	31,54		35.000		35.000
2022-03-04	2022-03-04	4	Thomson Mary Christina	SRRA	Stock Option (Right to Buy)	M - Exercise	D	13,04		2.000		0
2022-03-04	2022-03-04	4	Thomson Mary Christina	SRRA	Common Stock	S - Sale	D		30,5981	-2.000	-61		0
2022-03-04	2022-03-04	4	Thomson Mary Christina	SRRA	Common Stock	M - Exercise	D		13,0400	2.000	26		2.000
2022-02-08	2022-02-07	4	Turner William D.	SRRA	Stock Option (Right to Buy)	M - Exercise	D	12,05		10.000		0
2022-02-08	2022-02-07	4	Turner William D.	SRRA	Common Stock	S - Sale	D		32,3225	-10.000	-323		0
2022-02-08	2022-02-07	4	Turner William D.	SRRA	Common Stock	M - Exercise	D		12,0500	10.000	120		10.000
2022-02-04	2022-02-04	4	Thomson Mary Christina	SRRA	Stock Option (Right to Buy)	M - Exercise	D	13,04		2.000		0
2022-02-04	2022-02-04	4	Thomson Mary Christina	SRRA	Common Stock	S - Sale	D		29,7800	-2.000	-60		0
2022-02-04	2022-02-04	4	Thomson Mary Christina	SRRA	Common Stock	M - Exercise	D		13,0400	2.000	26		2.000
2022-02-02	2022-02-02	4	Longitude Capital Partners III, LLC	SRRA	Common Stock	P - Purchase	I		27,0000	175.000	4.725		175.000
2022-02-02	2022-02-02	4	Richardson Joshua	SRRA	Common Stock	P - Purchase	I		27,0000	175.000	4.725		175.000
2022-02-02		3	Longitude Prime Fund, L.P.	SRRA	Common Stock		I						175.000
2022-02-01	2022-01-31	4	Sinclair Andrew See footnotes	SRRA	Common Stock, $0.001 par value	P - Purchase	I		27,0000	150.000	4.050		1.314.127
2022-02-01	2022-01-28	4	Sinclair Andrew See footnotes	SRRA	Series B Warrants (right to buy)	X - Other	I	13,20		-287.471		0
2022-02-01	2022-01-28	4	Sinclair Andrew See footnotes	SRRA	Common Stock, $0.001 par value	X - Other	I		13,2000	287.471	3.795		1.164.127
2022-02-01	2022-01-31	4	Abingworth LLP	SRRA	Common Stock, $0.001 par value	P - Purchase	I		27,0000	150.000	4.050		1.314.127
2022-02-01	2022-01-28	4	Abingworth LLP	SRRA	Series B Warrants (right to buy)	X - Other	I	13,20		-287.471		0
2022-02-01	2022-01-28	4	Abingworth LLP	SRRA	Common Stock, $0.001 par value	X - Other	I		13,2000	287.471	3.795		1.164.127
2022-01-31	2022-01-31	4	Vivo Opportunity, LLC By Vivo Opportunity Fund, L.P.	SRRA	Common Stock	P - Purchase	I		27,0000	800.000	21.600		2.735.853
2022-01-31	2022-01-31	4	Aggarwal Gaurav By Vivo Opportunity Fund, L.P.	SRRA	Common Stock	P - Purchase	I		27,0000	800.000	21.600		2.735.853
2022-01-28	2022-01-26	4	Ashiya Mona See footnotes	SRRA	Series B Warrants	X - Other	I	13,20		-56.244		0
2022-01-28	2022-01-26	4	Ashiya Mona See footnotes	SRRA	Series B Warrants	X - Other	I	13,20		-56.244		0
2022-01-28	2022-01-26	4	Ashiya Mona See footnotes	SRRA	Series B Warrants	X - Other	I	13,20		-374.962		0
2022-01-28	2022-01-26	4	Ashiya Mona See footnotes (4),	SRRA	Common Stock	X - Other	I		13,2000	56.244	742		226.704
2022-01-28	2022-01-26	4	Ashiya Mona See footnotes	SRRA	Common Stock	X - Other	I		13,2000	56.244	742		226.704
2022-01-28	2022-01-26	4	Ashiya Mona See footnotes (4),	SRRA	Common Stock	X - Other	I		13,2000	374.962	4.949		1.511.362
2022-01-28	2022-01-26	4	ORBIMED ADVISORS LLC	SRRA	Series B Warrants	X - Other	I	13,20		-56.244		0
2022-01-28	2022-01-26	4	ORBIMED ADVISORS LLC	SRRA	Series B Warrants	X - Other	I	13,20		-56.244		0
2022-01-28	2022-01-26	4	ORBIMED ADVISORS LLC	SRRA	Series B Warrants	X - Other	I	13,20		-374.962		0
2022-01-28	2022-01-26	4	ORBIMED ADVISORS LLC	SRRA	Common Stock	X - Other	I		13,2000	56.244	742		226.704
2022-01-28	2022-01-26	4	ORBIMED ADVISORS LLC See footnote (4),	SRRA	Common Stock	X - Other	I		13,2000	56.244	742		226.704
2022-01-28	2022-01-26	4	ORBIMED ADVISORS LLC See footnote (4),	SRRA	Common Stock	X - Other	I		13,2000	374.962	4.949		1.511.362
2022-01-28	2022-01-26	4	Vivo Opportunity, LLC By: Vivo Capital Fund IX, L.P.	SRRA	Series B Warrant (Right to Purchase )	X - Other	I	13,20	13,2000	-324.740	-4.287	0
2022-01-28	2022-01-26	4	Vivo Opportunity, LLC By: Vivo Opportunity Fund, L.P.	SRRA	Series B Warrant (Right to Purchase )	X - Other	I	13,20	13,2000	-1.455.384	-19.211	0
2022-01-28	2022-01-26	4	Vivo Opportunity, LLC By: Vivo Ventures Fund VII, L.P. and Vivo Ventures VII Affiliates Fund, L.P.	SRRA	Series B Warrant (Right to Purchase )	X - Other	I	13,20	13,2000	-75.749	-1.000	0
2022-01-28	2022-01-26	4	Vivo Opportunity, LLC By: Vivo Capital Fund IX, L.P.	SRRA	Common Stock	X - Other	I		13,2000	107.164	1.415		431.947
2022-01-28	2022-01-26	4	Vivo Opportunity, LLC By: Vivo Opportunity Fund, L.P.	SRRA	Common Stock	X - Other	I		13,2000	480.277	6.340		1.935.853
2022-01-28	2022-01-26	4	Vivo Opportunity, LLC By: Vivo Ventures Fund VII, L.P. and Vivo Ventures VII Affiliates Fund, L.P.	SRRA	Common Stock	X - Other	I		13,2000	24.996	330		161.712
2022-01-28	2022-01-26	4	Aggarwal Gaurav By Vivo Opportunity Fund, L.P.	SRRA	Series B Warrant (Right to Purchase)	X - Other	I	13,20	13,2000	-1.455.384	-19.211	0
2022-01-28	2022-01-26	4	Aggarwal Gaurav By Vivo Opportunity Fund, L.P.	SRRA	Common Stock	X - Other	I		13,2000	480.277	6.340		1.935.853
2022-01-28	2022-01-28	4	Klencke Barbara	SRRA	Stock Option (Right to Buy)	A - Award	D	12,15		12.250		12.250
2022-01-28	2022-01-28	4	Kowalski Mark	SRRA	Stock Option (Right to Buy)	A - Award	D	12,15		12.250		12.250
2022-01-28	2022-01-28	4	Norrett Kevin	SRRA	Stock Option (Right to Buy)	A - Award	D	12,15		12.250		12.250
2022-01-28	2022-01-28	4	DILLY STEPHEN GEORGE	SRRA	Stock Option (Right to Buy)	A - Award	D	12,15		65.000		65.000
2022-01-28	2022-01-28	4	Jagpal Sukhi	SRRA	Stock Option (Right to Buy)	A - Award	D	12,15		12.250		12.250
2022-01-28	2022-01-28	4	Thomson Mary Christina	SRRA	Stock Option (Right to Buy)	A - Award	D	12,15		12.250		12.250
2022-01-28	2022-01-26	4	Thomson Mary Christina	SRRA	Stock Option (Right to Buy)	M - Exercise	D	13,04		2.000		0
2022-01-28	2022-01-26	4	Thomson Mary Christina	SRRA	Common Stock	S - Sale	D		29,0000	-2.000	-58		0
2022-01-28	2022-01-26	4	Thomson Mary Christina	SRRA	Common Stock	M - Exercise	D		13,0400	2.000	26		2.000
2022-01-28	2022-01-28	4	Turner William D.	SRRA	Stock Option (Right to Buy)	A - Award	D	12,15		12.250		12.250
2022-01-28	2022-01-26	4	Turner William D.	SRRA	Stock Option (Right to Buy)	M - Exercise	D	12,05		5.000		0
2022-01-28	2022-01-26	4	Turner William D.	SRRA	Common Stock	S - Sale	D		27,0500	-5.000	-135		0
2022-01-28	2022-01-26	4	Turner William D.	SRRA	Common Stock	M - Exercise	D		12,0500	5.000	60		5.000
2022-01-27	2022-01-25	4	Longitude Capital Partners III, LLC	SRRA	Series B Warrants	X - Other	I	13,20	13,2000	-1.477.125	-19.498	0
2022-01-27	2022-01-25	4	Longitude Capital Partners III, LLC	SRRA	Common Stock	X - Other	I		13,2000	487.451	6.434		1.964.771
2022-01-27	2022-01-25	4	Richardson Joshua By Longitude Venture Partners III, L.P.	SRRA	Series B Warrants	X - Other	I	13,20	13,2000	-1.477.125	-19.498	0
2022-01-27	2022-01-25	4	Richardson Joshua By Longitude Venture Partners III, L.P.	SRRA	Common Stock	X - Other	I		13,2000	487.451	6.434		1.964.771
2021-11-24	2021-11-24	4	Collard Craig A	SRRA	Common Stock	P - Purchase	D		23,0850	7.899	182		13.500
2021-11-24	2021-11-23	4	Collard Craig A	SRRA	Common Stock	P - Purchase	D		22,9450	5.601	129		5.601
2021-11-05		3	Abingworth LLP	SRRA	Common Stock, $0.001 par value		I						878.656
2021-06-28	2021-03-15	4	Thomson Mary Christina	SRRA	Stock Option (Right to Buy)	A - Award	D	16,73		12.900		12.900
2021-06-28	2020-07-28	4	Thomson Mary Christina	SRRA	Stock option (right to buy)	A - Award	D	13,04		100.000		100.000
2021-06-09	2021-06-08	4	Cooper Jeffrey H	SRRA	Stock Option (Right To Buy)	A - Award	D	18,11		6.000		6.000
2021-06-09	2021-06-08	4	Collard Craig A	SRRA	Stock Option (Right To Buy)	A - Award	D	18,11		6.000		6.000
2021-06-09	2021-06-08	4	Pelzer Robert	SRRA	Stock Option (Right To Buy)	A - Award	D	18,11		6.000		6.000
2021-06-09	2021-06-08	4	Ashiya Mona	SRRA	Stock Option (Right To Buy)	A - Award	D	18,11		6.000		6.000
2021-06-09	2021-06-08	4	Allen Andrew R	SRRA	Stock Option (Right To Buy)	A - Award	D	18,11		6.000		6.000
2021-06-09	2021-06-08	4	Aggarwal Gaurav	SRRA	Stock Option (Right To Buy)	A - Award	D	18,11		6.000		6.000
2021-06-09	2021-06-08	4	Sinclair Andrew	SRRA	Stock Option (Right To Buy)	A - Award	D	18,11		6.000		6.000
2021-06-09	2021-06-08	4	Richardson Joshua	SRRA	Stock Option (Right To Buy)	A - Award	D	18,11		6.000		6.000
2021-06-04	2021-06-02	4	Oliger Christy J.	SRRA	Stock Option (right to buy)	A - Award	D	17,76		18.000		18.000
2021-06-04	2021-06-02	4	Erbez Georgia	SRRA	Stock Option (right to buy)	A - Award	D	17,76		18.000		18.000
2021-05-20	2021-05-19	4	DILLY STEPHEN GEORGE	SRRA	Common Stock	P - Purchase	D		17,8300	5.000	89		5.000
2021-03-17	2021-03-15	4	Turner William D.	SRRA	Stock Option (Right to Buy)	A - Award	D	16,73		12.300		12.300
2021-03-17	2021-03-15	4	Thomson Christina	SRRA	Stock Option (Right to Buy)	A - Award	D	16,73		12.900		12.900
2021-03-17	2021-03-15	4	Norrett Kevin	SRRA	Stock Option (Right to Buy)	A - Award	D	16,73		11.700		11.700
2021-03-17	2021-03-15	4	Kowalski Mark	SRRA	Stock Option (Right to Buy)	A - Award	D	16,73		30.000		30.000
2021-03-17	2021-03-15	4	Jagpal Sukhi	SRRA	Stock Option (Right to Buy)	A - Award	D	16,73		30.000		30.000
2021-03-17	2021-03-15	4	Klencke Barbara	SRRA	Stock Option (Right to Buy)	A - Award	D	16,73		30.000		30.000
2021-03-17	2021-03-15	4	DILLY STEPHEN GEORGE	SRRA	Stock Option (Right to Buy)	A - Award	D	16,73		92.000		92.000
2020-08-18	2020-08-18	4	Klencke Barbara By spouse	SRRA	Common Stock	P - Purchase	I		12,2519	3.325	41		5.000
2020-08-18	2020-08-18	4	Klencke Barbara	SRRA	Common Stock	P - Purchase	D		12,2201	5.950	73		10.000
2020-08-12	2020-08-12	4	Jagpal Sukhi	SRRA	Stock Option (right to buy)	A - Award	D	12,15		5.887		5.887
2020-08-12	2020-08-12	4	Kowalski Mark	SRRA	Stock Option (right to buy)	A - Award	D	12,15		24.970		24.970
2020-08-11	2020-08-10	4	Norrett Kevin	SRRA	Stock option (right to buy)	A - Award	D	12,05		100.000		100.000
2020-08-06	2020-08-04	4	Turner William D.	SRRA	Stock option (right to buy)	A - Award	D	12,05		100.000		100.000
2020-07-29	2020-07-28	4	Thomson Christina	SRRA	Stock option (right to buy)	A - Award	D	13,04		100.000		100.000
2020-06-10	2020-06-09	4	Aggarwal Gaurav	SRRA	Stock Option (right to buy)	A - Award	D	13,98		6.874		6.874
2020-06-10	2020-06-09	4	Allen Andrew R	SRRA	Stock Option (right to buy)	A - Award	D	13,98		12.030		12.030
2020-06-10	2020-06-09	4	Ashiya Mona	SRRA	Stock Option (right to buy)	A - Award	D	13,98		6.874		6.874
2020-06-10	2020-06-09	4	Cooper Jeffrey H	SRRA	Stock Option (right to buy)	A - Award	D	13,98		18.061		18.061
2020-06-10	2020-06-09	4	Pelzer Robert	SRRA	Stock Option (right to buy)	A - Award	D	13,98		16.686		16.686
2020-06-10	2020-06-09	4	Richardson Joshua	SRRA	Stock Option (right to buy)	A - Award	D	13,98		6.874		6.874
2020-06-10	2020-06-09	4	Sinclair Andrew	SRRA	Stock Option (right to buy	A - Award	D	13,98		6.874		6.874
2020-06-02	2020-06-01	4	DILLY STEPHEN GEORGE	SRRA	Stock Option (right to buy)	A - Award	D	14,03		520.000		520.000
2020-05-29	2020-05-28	4	Collard Craig A	SRRA	Stock Option (right to buy)	A - Award	D	13,88		10.000		10.000
2020-02-27	2020-02-25	4	Glover Nicholas	SRRA	Stock Option (right to buy)	A - Award	D	13,31		359.158		359.158
2020-02-27	2020-02-25	4	Jagpal Sukhi	SRRA	Stock Option (right to buy)	A - Award	D	13,31		94.113		94.113
2020-02-27	2020-02-25	4	Klencke Barbara	SRRA	Stock Option (right to buy)	A - Award	D	13,31		167.091		167.091
2020-02-27	2020-02-25	4	Kowalski Mark	SRRA	Stock Option (right to buy)	A - Award	D	13,31		75.030		75.030
2020-02-03	2020-01-29	4/A	Sinclair Andrew See footnotes	SRRA	Series A Convertible Voting Preferred Stock	C - Conversion	I			-11.500		0
2020-02-03	2020-01-29	4/A	Sinclair Andrew See footnotes	SRRA	Common Stock	C - Conversion	I			871.240			876.656
2020-01-31	2020-01-29	4	ORBIMED ADVISORS LLC See footnotes	SRRA	Series A Convertible Voting Preferred Stock	C - Conversion	I			-19.500		0
2020-01-31	2020-01-29	4	ORBIMED ADVISORS LLC See footnotes	SRRA	Common Stock	C - Conversion	I			1.477.320			1.477.320
2020-01-31	2020-01-29	4	Aggarwal Gaurav By Vivo Opportunity Fund, LP	SRRA	Series A Convertible Voting Preferred Stock	C - Conversion	I			-19.213		0
2020-01-31	2020-01-29	4	Aggarwal Gaurav By Vivo Opportunity Fund, LP	SRRA	Common Stock	C - Conversion	I			1.455.576			1.455.576
2020-01-31	2020-01-29	4	Ashiya Mona See footnotes	SRRA	Series A Convertible Voting Preferred Stock	C - Conversion	I			-19.500		0
2020-01-31	2020-01-29	4	Ashiya Mona See footnotes	SRRA	Common Stock	C - Conversion	I			1.477.320			1.477.320
2020-01-31	2020-01-29	4	Richardson Joshua By Longitude Venture Partners III, L.P.	SRRA	Series A Convertible Voting Preferred Stock	C - Conversion	I			-19.500		0
2020-01-31	2020-01-29	4	Richardson Joshua By Longitude Venture Partners III, L.P.	SRRA	Common Stock	C - Conversion	I			1.477.320			1.477.320
2020-01-31	2020-01-29	4	Longitude Capital Partners III, LLC	SRRA	Series A Convertible Voting Preferred Stock	C - Conversion	I			-19.500		0
2020-01-31	2020-01-29	4	Longitude Capital Partners III, LLC	SRRA	Common Stock	C - Conversion	I			1.477.320			1.477.320
2020-01-31	2020-01-29	4	Vivo Opportunity, LLC By: Vivo Capital Fund IX, L.P.	SRRA	Series A Convertible Voting Preferred Stock	C - Conversion	I			-4.287		0
2020-01-31	2020-01-29	4	Vivo Opportunity, LLC By Vivo Opportunity Fund, L.P.	SRRA	Series A Convertible Voting Preferred Stock	C - Conversion	I			-19.213		0
2020-01-31	2020-01-29	4	Vivo Opportunity, LLC By: Vivo Ventures Fund VII, L.P. and Vivo Ventures VII Affiliates Fund, L.P.	SRRA	Series A Convertible Voting Preferred Stock	C - Conversion	I			-1.000		0
2020-01-31	2020-01-29	4	Vivo Opportunity, LLC By: Vivo Capital Fund IX, L.P.	SRRA	Common Stock	C - Conversion	I			324.783			324.783
2020-01-31	2020-01-29	4	Vivo Opportunity, LLC By Vivo Opportunity Fund, L.P.	SRRA	Common Stock	C - Conversion	I			1.455.576			1.455.576
2020-01-31	2020-01-29	4	Vivo Opportunity, LLC By: Vivo Ventures Fund VII, L.P. and Vivo Ventures VII Affiliates Fund, L.P.	SRRA	Common Stock	C - Conversion	I			75.759			136.715
2020-01-31	2020-01-29	4	Sinclair Andrew See footnotes	SRRA	Series A Convertible Voting Preferred Stock	C - Conversion	I			-11.500		0
2020-01-31	2020-01-29	4	Sinclair Andrew See footnotes	SRRA	Common Stock	C - Conversion	I			871.125			876.542
2019-12-03	2019-11-29	4	Sinclair Andrew	SRRA	Stock Option (right to buy)	A - Award	D	0,35		60.000		60.000
2019-12-03	2019-11-29	4	Aggarwal Gaurav	SRRA	Stock Option (Right to Buy)	A - Award	D	0,35		60.000		60.000
2019-12-03	2019-11-29	4	Ashiya Mona	SRRA	Stock Option (Right to Buy)	A - Award	D	0,35		60.000		60.000
2019-12-03	2019-11-29	4	Richardson Joshua	SRRA	Stock Option (Right to Buy)	A - Award	D	0,35		60.000		60.000
2019-12-02		3	Vivo Ventures VII Affiliates Fund, L.P. By: Vivo Ventures Fund VII, L.P. and Vivo Ventures VII Affiliates Fund, L.P.	SRRA	Common Stock		I						4.876.540
2019-12-02		3	Vivo Ventures VII Affiliates Fund, L.P. By: Vivo Ventures Fund VII, L.P. and Vivo Ventures VII Affiliates Fund, L.P.	SRRA	Common Stock		I						4.876.540
2019-12-02		3	Vivo Ventures VII Affiliates Fund, L.P. By: Vivo Ventures Fund VII, L.P. and Vivo Ventures VII Affiliates Fund, L.P.	SRRA	Common Stock		I						4.876.540
2019-12-02		3	Vivo Ventures VII Affiliates Fund, L.P. By: Vivo Ventures Fund VII, L.P. and Vivo Ventures VII Affiliates Fund, L.P.	SRRA	Common Stock		I						4.876.540
2019-12-02		3	Vivo Ventures VII Affiliates Fund, L.P. By: Vivo Ventures Fund VII, L.P. and Vivo Ventures VII Affiliates Fund, L.P.	SRRA	Common Stock		I						4.876.540
2019-12-02		3	Vivo Ventures VII Affiliates Fund, L.P. By: Vivo Ventures Fund VII, L.P. and Vivo Ventures VII Affiliates Fund, L.P.	SRRA	Common Stock		I						4.876.540
2019-12-02		3	Vivo Ventures VII Affiliates Fund, L.P. By: Vivo Ventures Fund VII, L.P. and Vivo Ventures VII Affiliates Fund, L.P.	SRRA	Common Stock		I						4.876.540
2019-12-02		3	Vivo Ventures VII Affiliates Fund, L.P. By: Vivo Ventures Fund VII, L.P. and Vivo Ventures VII Affiliates Fund, L.P.	SRRA	Common Stock		I						4.876.540
2019-12-02		3	Vivo Ventures VII Affiliates Fund, L.P. By: Vivo Ventures Fund VII, L.P. and Vivo Ventures VII Affiliates Fund, L.P.	SRRA	Common Stock		I						4.876.540
2019-11-26		3	Sinclair Andrew See Footnotes	SRRA	Common Stock, $0.001 par value		I						433.334
2019-11-26		3	Sinclair Andrew See Footnotes	SRRA	Common Stock, $0.001 par value		I						433.334
2019-11-26		3	Sinclair Andrew See Footnotes	SRRA	Common Stock, $0.001 par value		I						433.334
2019-08-26	2019-08-23	4	Klencke Barbara	SRRA	Common Stock	P - Purchase	D		0,4387	108.000	47		162.000
2019-08-26	2019-08-22	4	Klencke Barbara	SRRA	Common Stock	P - Purchase	D		0,4499	54.000	24		54.000
2019-08-26	2019-08-22	4	Klencke Barbara By spouse	SRRA	Common Stock	P - Purchase	I		0,4323	67.000	29		67.000
2019-06-12	2019-06-11	4	Cooper Jeffrey H	SRRA	Stock Option (right to buy)	A - Award	D	0,66		30.000		30.000
2019-06-12	2019-06-11	4	ESTES DANIEL	SRRA	Stock Option (right to buy)	A - Award	D	0,66		30.000		30.000
2019-06-12	2019-06-11	4	Nguyen Tran	SRRA	Stock Option (right to buy)	A - Award	D	0,66		30.000		30.000
2019-06-12	2019-06-11	4	ONETTO NICOLE	SRRA	Stock Option (right to buy)	A - Award	D	0,66		30.000		30.000
2019-06-12	2019-06-11	4	Parfet Donald R	SRRA	Stock Option (right to buy)	A - Award	D	0,66		30.000		30.000
2019-06-12	2019-06-11	4	Pelzer Robert	SRRA	Stock Option (right to buy)	A - Award	D	0,66		30.000		30.000
2019-06-12	2019-06-11	4	Allen Andrew R	SRRA	Stock Option (right to buy)	A - Award	D	0,66		30.000		30.000
2019-03-05	2019-03-04	4	Glover Nicholas	SRRA	Stock Option (right to buy)	A - Award	D	1,96		607.500		607.500
2019-03-05	2019-03-04	4	Hassig Christian	SRRA	Stock Option (right to buy)	A - Award	D	1,96		155.000		155.000
2019-03-05	2019-03-04	4	Jagpal Sukhi	SRRA	Stock Option (right to buy)	A - Award	D	1,96		200.000		200.000
2019-03-05	2019-03-04	4	Klencke Barbara	SRRA	Stock Option (right to buy)	A - Award	D	1,96		200.000		200.000
2019-03-05	2019-03-04	4	Kowalski Mark	SRRA	Stock Option (right to buy)	A - Award	D	1,96		200.000		200.000
2018-12-11	2018-12-10	4	Allen Andrew R	SRRA	Common Stock	P - Purchase	D		1,6400	66.000	108		66.000
2018-06-14	2018-06-12	4	Pelzer Robert	SRRA	Stock Option (right to buy)	A - Award	D	3,27		25.000		25.000
2018-06-14	2018-06-12	4	ESTES DANIEL	SRRA	Stock Option (right to buy)	A - Award	D	3,27		25.000		25.000
2018-06-14	2018-06-12	4	Allen Andrew R	SRRA	Stock Option (right to buy)	A - Award	D	3,27		25.000		25.000
2018-06-14	2018-06-12	4	Cooper Jeffrey H	SRRA	Stock Option (right to buy)	A - Award	D	3,27		25.000		25.000
2018-06-14	2018-06-12	4	Nguyen Tran	SRRA	Stock Option (right to buy)	A - Award	D	3,27		25.000		25.000
2018-06-14	2018-06-12	4	ONETTO NICOLE	SRRA	Stock Option (right to buy)	A - Award	D	3,27		25.000		25.000
2018-06-14	2018-06-12	4	Parfet Donald R	SRRA	Stock Option (right to buy)	A - Award	D	3,27		25.000		25.000
2018-03-07	2018-03-06	4	Glover Nicholas	SRRA	Stock Option (right to buy)	A - Award	D	2,36		562.780		562.780
2018-03-07	2018-03-06	4	Hassig Christian	SRRA	Stock Option (right to buy)	A - Award	D	2,36		205.180		205.180
2018-03-07	2018-03-06	4	Jagpal Sukhi	SRRA	Stock Option (right to buy)	A - Award	D	2,36		180.360		180.360
2018-03-07	2018-03-06	4	Klencke Barbara	SRRA	Stock Option (right to buy)	A - Award	D	2,36		180.360		180.360
2018-03-07	2018-03-06	4	Kowalski Mark	SRRA	Stock Option (right to buy)	A - Award	D	2,36		155.000		155.000
2018-03-07	2018-03-06	4	You Angie	SRRA	Stock Option (right to buy)	A - Award	D	2,36		180.360		180.360
2018-01-08	2018-01-04	4	Parfet Donald R	SRRA	Common Stock	J - Other	D			1.380			77.235
2018-01-08	2018-01-04	4	Parfet Donald R Apjohn Ventures, LLC	SRRA	Common Stock	J - Other	I			-2.760			0
2018-01-08	2018-01-04	4	Parfet Donald R Apjohn Ventures, LLC	SRRA	Common Stock	J - Other	I			1.068			2.760
2018-01-08	2018-01-04	4	Parfet Donald R Apjohn Ventures, LLC	SRRA	Common Stock	J - Other	I			1.692			1.692
2018-01-08	2018-01-04	4	Parfet Donald R By Donald R. Parfet 2006 Trust, Dated May 1, 2006	SRRA	Common Stock	J - Other	I			3.383			390.913
2017-11-13	2017-11-10	4	Allen Andrew R	SRRA	Stock Option (Right to Buy)	A - Award	D	1,92		50.000		50.000
2017-10-25		3	Allen Andrew R	SRRA	No securities beneficially owned.		D						0
2017-06-14	2017-06-13	4	Cooper Jeffrey H	SRRA	Stock Option (right to buy)	A - Award	D	1,13		25.000		25.000
2017-06-14	2017-06-13	4	Nguyen Tran	SRRA	Stock Option (right to buy)	A - Award	D	1,13		25.000		25.000
2017-06-14	2017-06-13	4	ONETTO NICOLE	SRRA	Stock Option (right to buy)	A - Award	D	1,13		25.000		25.000
2017-06-14	2017-06-13	4	Parfet Donald R	SRRA	Stock Option (right to buy)	A - Award	D	1,13		25.000		25.000
2017-06-14	2017-06-13	4	Pelzer Robert	SRRA	Stock Option (right to buy)	A - Award	D	1,13		25.000		25.000
2017-05-30	2017-05-25	4	ESTES DANIEL	SRRA	Stock Option (Right to Buy)	A - Award	D	1,20		50.000		50.000
2017-04-11		3	ESTES DANIEL	SRRA	No securities beneficially owned		D						0
2017-03-09	2017-03-08	4	You Angie	SRRA	Common Stock	P - Purchase	D		1,4300	30.000	43		133.252
2017-03-08	2017-03-06	4	You Angie	SRRA	Stock Option (right to buy)	A - Award	D	1,45		70.000		70.000
2017-03-08	2017-03-06	4	Jagpal Sukhi	SRRA	Stock Option (right to buy)	A - Award	D	1,45		70.000		70.000
2017-03-08	2017-03-06	4	Klencke Barbara	SRRA	Stock Option (right to buy)	A - Award	D	1,45		70.000		70.000
2017-03-08	2017-03-06	4	Glover Nicholas	SRRA	Stock Option (right to buy)	A - Award	D	1,45		195.000		195.000
2017-02-24		3	Heron Patrick J	SRRA	Common Stock		D						10.298.316
2017-02-24		3	Heron Patrick J	SRRA	Common Stock		D						14.038.047
2017-02-24		3	Heron Patrick J	SRRA	Common Stock		D						10.298.316
2017-02-24		3	Heron Patrick J	SRRA	Common Stock		D						14.038.047
2017-02-24		3	Heron Patrick J	SRRA	Common Stock		D						10.298.316
2017-02-24		3	Heron Patrick J	SRRA	Common Stock		D						14.038.047
2017-02-24		3	Heron Patrick J	SRRA	Common Stock		D						10.298.316
2017-02-24		3	Heron Patrick J	SRRA	Common Stock		D						14.038.047
2017-02-24		3	Heron Patrick J	SRRA	Common Stock		D						10.298.316
2017-02-24		3	Heron Patrick J	SRRA	Common Stock		D						14.038.047
2017-02-24		3	Heron Patrick J	SRRA	Common Stock		D						10.298.316
2017-02-24		3	Heron Patrick J	SRRA	Common Stock		D						14.038.047
2017-02-24		3	Heron Patrick J	SRRA	Common Stock		D						10.298.316
2017-02-24		3	Heron Patrick J	SRRA	Common Stock		D						14.038.047
2017-02-24		3	Heron Patrick J	SRRA	Common Stock		D						10.298.316
2017-02-24		3	Heron Patrick J	SRRA	Common Stock		D						14.038.047
2017-02-24		3	Heron Patrick J	SRRA	Common Stock		D						14.038.047
2017-02-24		3	Heron Patrick J	SRRA	Common Stock		D						14.038.047
2017-02-24		3	Heron Patrick J	SRRA	Common Stock		D						10.298.316
2017-02-24		3	Heron Patrick J	SRRA	Common Stock		D						14.038.047
2017-02-24		3	Heron Patrick J	SRRA	Common Stock		D						10.298.316
2017-02-24		3	Heron Patrick J	SRRA	Common Stock		D						10.298.316
2017-02-16	2017-02-14	4	Topper James N By Frazier Life Sciences VIII, L.P.	SRRA	Common Stock	P - Purchase	I		1,3500	5.925.926	8.000		5.925.926
2017-01-04		3	Kowalski Mark	DNAI	No securities beneficially held		D						0
2017-01-04	2017-01-03	4	Kowalski Mark	DNAI	Stock Option (right to buy Class A Common Stock)	A - Award	D	1,54		300.000		300.000
2016-11-10	2016-11-08	4	Parfet Donald R	DNAI	Common Stock	J - Other	D			2.403			75.855
2016-11-10	2016-11-08	4	Parfet Donald R Apjohn Ventures, LLC	DNAI	Common Stock	J - Other	I			-4.806			0
2016-11-10	2016-11-08	4	Parfet Donald R Apjohn Ventures, LLC	DNAI	Common Stock	J - Other	I			1.423			4.806
2016-11-10	2016-11-08	4	Parfet Donald R Apjohn Ventures, LLC	DNAI	Common Stock	J - Other	I			3.383			3.383
2016-11-10	2016-11-08	4	Parfet Donald R By Donald R. Parfet 2006 Trust, Dated May 1, 2006	DNAI	Common Stock	J - Other	I			6.767			387.530
2016-10-04	2016-09-30	4	Jagpal Sukhi	DNAI	Stock Option (right to buy)	A - Award	D	1,82		168.000		168.000
2016-10-04	2016-09-30	4	Glover Nicholas	DNAI	Stock Option (right to buy)	A - Award	D	1,82		500.000		500.000
2016-10-04	2016-09-30	4	Klencke Barbara	DNAI	Stock Option (right to buy)	A - Award	D	1,82		456.000		456.000
2016-10-04	2016-09-30	4	You Angie	DNAI	Stock Option (right to buy)	A - Award	D	1,82		200.000		200.000
2016-09-30	2016-09-29	4	Parfet Donald R	DNAI	Common Stock	J - Other	D			1.202			73.452
2016-09-30	2016-09-29	4	Parfet Donald R By Apjohn Ventures, LLC	DNAI	Common Stock	J - Other	I			-2.403			0
2016-09-30	2016-09-29	4	Parfet Donald R By Apjohn Ventures, LLC	DNAI	Common Stock	J - Other	I			711			2.403
2016-09-30	2016-09-29	4	Parfet Donald R By Apjohn Ventures, LLC	DNAI	Common Stock	J - Other	I			1.692			1.692
2016-09-30	2016-09-29	4	Parfet Donald R By Donald R. Parfet 2006 Trust, Dated May 1, 2006	DNAI	Common Stock	J - Other	I			3.384			380.763
2016-06-20	2016-06-16	4	ONETTO NICOLE	DNAI	Stock Option (right to buy)	A - Award	D	2,06		38.835		38.835
2016-06-20	2016-06-16	4	Pelzer Robert	DNAI	Stock Option (right to buy)	A - Award	D	2,06		38.835		38.835
2016-06-20	2016-06-16	4	Parfet Donald R	DNAI	Stock Option (right to buy)	A - Award	D	2,06		38.835		38.835
2016-06-20	2016-06-16	4	Topper James N	DNAI	Stock Option (right to buy)	A - Award	D	2,06		38.835		38.835
2016-06-13	2016-06-09	4	Cooper Jeffrey H	DNAI	Stock Option (right to buy)	A - Award	D	2,06		77.670		77.670
2016-06-13	2016-06-09	4	Nguyen Tran	DNAI	Stock Option (right to buy)	A - Award	D	2,06		77.670		77.670
2016-05-17	2016-05-13	4	Parfet Donald R By Donald R. Parfet 2006 Trust, Dated May 1, 2006	DNAI	Common Stock	J - Other	I			3.204			377.379
2016-03-24		3	Nguyen Tran	DNAI	No securities beneficially held		D						0
2016-03-24		3	Cooper Jeffrey H	DNAI	No securities beneficially held		D						0
2016-03-24	2016-03-22	4	Chapman Wendy	DNAI	Stock Option (right to buy)	M - Exercise	D	0,97		-3.000		76.248
2016-03-24	2016-03-22	4	Chapman Wendy	DNAI	Common Stock	S - Sale	D		7,0078	-3.000	-21		0
2016-03-24	2016-03-22	4	Chapman Wendy	DNAI	Common Stock	M - Exercise	D		0,9690	3.000	3		3.000
2016-03-10	2016-03-08	4	Messmann Richard A	DNAI	Stock Option (right to buy)	A - Award	D	6,58		25.000		25.000
2016-03-10	2016-03-08	4	Lovejoy Chandra D	DNAI	Stock Option (right to buy)	A - Award	D	6,58		31.000		31.000
2016-03-10	2016-03-08	4	Jagpal Sukhi	DNAI	Stock Option (right to buy)	A - Award	D	6,58		48.750		48.750
2016-03-10	2016-03-08	4	Glover Nicholas	DNAI	Stock Option (right to buy)	A - Award	D	6,58		161.250		161.250
2016-03-10	2016-03-08	4	Klencke Barbara	DNAI	Stock Option (right to buy)	A - Award	D	6,58		82.500		82.500
2016-03-10	2016-03-08	4	Chapman Wendy	DNAI	Stock Option (right to buy)	A - Award	D	6,58		25.000		25.000
2016-03-10	2016-03-08	4	You Angie	DNAI	Stock Option (right to buy)	A - Award	D	6,58		75.000		75.000
2016-02-24	2016-02-22	4	Chapman Wendy	DNAI	Stock Option (right to buy)	M - Exercise	D	0,97		-3.000		79.248
2016-02-24	2016-02-22	4	Chapman Wendy	DNAI	Common Stock	S - Sale	D		7,0600	-3.000	-21		0
2016-02-24	2016-02-22	4	Chapman Wendy	DNAI	Common Stock	M - Exercise	D		0,9690	3.000	3		3.000
2016-01-25	2016-01-22	4	Chapman Wendy	DNAI	Stock Option (right to buy)	M - Exercise	D	0,97		-5.000		82.248
2016-01-25	2016-01-22	4	Chapman Wendy	DNAI	Common Stock	S - Sale	D		9,3946	-5.000	-47		0
2016-01-25	2016-01-22	4	Chapman Wendy	DNAI	Common Stock	M - Exercise	D		0,9690	5.000	5		5.000
2016-01-22	2016-01-22	4	Rodigueza Wendi	DNAI	Common Stock	S - Sale	D		9,6600	-1.000	-10		156.276
2016-01-22	2016-01-21	4	Rodigueza Wendi	DNAI	Common Stock	S - Sale	D		10,3230	-1.000	-10		157.276
2016-01-22	2016-01-20	4	Rodigueza Wendi	DNAI	Common Stock	S - Sale	D		9,5900	-1.000	-10		158.276
2016-01-19	2016-01-15	4	Glover Nicholas	DNAI	Stock Option (right to buy)	M - Exercise	D	0,97		-5.000		864.219
2016-01-19	2016-01-15	4	Glover Nicholas	DNAI	Common Stock	S - Sale	D		10,0446	-5.000	-50		0
2016-01-19	2016-01-15	4	Glover Nicholas	DNAI	Common Stock	M - Exercise	D		0,9690	5.000	5		5.000
2016-01-14	2016-01-12	4	Lovejoy Chandra D	DNAI	Stock Option (right to buy)	M - Exercise	D	0,97		-7.551		46.140
2016-01-14	2016-01-12	4	Lovejoy Chandra D	DNAI	Common Stock	S - Sale	D		11,9282	-5.562	-66		0
2016-01-14	2016-01-12	4	Lovejoy Chandra D	DNAI	Common Stock	S - Sale	D		11,0628	-15.411	-170		5.562
2016-01-14	2016-01-12	4	Lovejoy Chandra D	DNAI	Common Stock	M - Exercise	D		0,9690	7.551	7		20.973
2015-12-02		3	Anderson Keith Edward	DNAI	No securities are beneficially owned		D						0
2015-12-02	2015-12-01	4	Anderson Keith Edward	DNAI	Stock Option (right to buy)	A - Award	D	18,33		100.000		100.000
2015-07-21	2015-07-21	4	Vitangcol Alvin By Capital Midwest Fund II, L.P.	DNAI	Series D Preferred Stock	C - Conversion	I			-287.631		0
2015-07-21	2015-07-21	4	Vitangcol Alvin By Capital Midwest Fund II, L.P.	DNAI	Series C Preferred Stock	C - Conversion	I			-471.242		0
2015-07-21	2015-07-21	4	Vitangcol Alvin By Capital Midwest Fund II, L.P.	DNAI	Series C Preferred Stock	F - Taxes	I			-38.824		471.242
2015-07-21	2015-07-21	4	Vitangcol Alvin By Capital Midwest Fund II, L.P.	DNAI	Series C Preferred Stock	X - Other	I			126.558		510.066
2015-07-21	2015-07-21	4	Vitangcol Alvin By Capital Midwest Fund II, L.P.	DNAI	Series C Preferred Stock Warrant (right to buy)	X - Other	I		5,2150	-126.558	-660	0
2015-07-21	2015-07-21	4	Vitangcol Alvin By Capital Midwest Fund II, L.P.	DNAI	Common Stock	J - Other	I		5,2150	39.889	208		798.762
2015-07-21	2015-07-21	4	Vitangcol Alvin By Capital Midwest Fund II, L.P.	DNAI	Common Stock	C - Conversion	I			287.631			758.873
2015-07-21	2015-07-21	4	Vitangcol Alvin By Capital Midwest Fund II, L.P.	DNAI	Common Stock	C - Conversion	I			471.242			471.242
2015-07-21	2015-07-21	4	Topper James N By Frazier Healthcare VI, L.P.	DNAI	Series D Preferred Stock	C - Conversion	I			-1.869.606		0
2015-07-21	2015-07-21	4	Topper James N By Frazier Healthcare VI, L.P.	DNAI	Common Stock	P - Purchase	I		17,0000	220.000	3.740		2.186.195
2015-07-21	2015-07-21	4	Topper James N By Frazier Healthcare VI, L.P.	DNAI	Common Stock	J - Other	I		5,2150	96.589	504		1.966.195
2015-07-21	2015-07-21	4	Topper James N By Frazier Healthcare VI, L.P.	DNAI	Common Stock	C - Conversion	I			1.869.606			1.869.606
2015-07-21	2015-07-21	4	Thompson Peter A. See Footnotes	DNAI	Series D Preferred Stock	C - Conversion	I			-1.725.790		0
2015-07-21	2015-07-21	4	Thompson Peter A. See Footnotes	DNAI	Common Stock	P - Purchase	I		17,0000	175.000	2.975		1.989.949
2015-07-21	2015-07-21	4	Thompson Peter A. See Footnotes	DNAI	Common Stock	J - Other	I		5,2150	89.159	465		1.814.949
2015-07-21	2015-07-21	4	Thompson Peter A. See Footnotes	DNAI	Common Stock	C - Conversion	I			1.725.790			1.725.790
2015-07-21	2015-07-21	4	Rodigueza Wendi	DNAI	Series B-1 Preferred Stock	C - Conversion	D			-1.966		0
2015-07-21	2015-07-21	4	Rodigueza Wendi	DNAI	Common Stock	C - Conversion	D			1.966			159.276
2015-07-21	2015-07-21	4	Parfet Donald R By Palmero Group LLC	DNAI	Series C Preferred Stock	C - Conversion	I			-13.130		0
2015-07-21	2015-07-21	4	Parfet Donald R By Palmero Group LLC	DNAI	Series A Preferred Stock	C - Conversion	I			-46.034		0
2015-07-21	2015-07-21	4	Parfet Donald R By Donald R. Parfet 2006 Trust, Dated May 1, 2006	DNAI	Series B-1 Preferred Stock	C - Conversion	I			-142.422		0
2015-07-21	2015-07-21	4	Parfet Donald R By Donald R. Parfet 2006 Trust, Dated May 1, 2006	DNAI	Series B Preferred Stock	C - Conversion	I			-189.933		0
2015-07-21	2015-07-21	4	Parfet Donald R By Donald R. Parfet 2006 Trust, Dated May 1, 2006	DNAI	Series A Preferred Stock	C - Conversion	I			-306		0
2015-07-21	2015-07-21	4	Parfet Donald R By Ann VanDeWater Parfet 2006 Revocable Trust, Dated May 5, 2006	DNAI	Series C Preferred Stock	C - Conversion	I			-65.938		0
2015-07-21	2015-07-21	4	Parfet Donald R By Ann VanDeWater Parfet 2006 Revocable Trust, Dated May 5, 2006	DNAI	Series B-1 Preferred Stock	C - Conversion	I			-121.242		0
2015-07-21	2015-07-21	4	Parfet Donald R By Ann VanDeWater Parfet 2006 Revocable Trust, Dated May 5, 2006	DNAI	Series B Preferred Stock	C - Conversion	I			-23.944		0
2015-07-21	2015-07-21	4	Parfet Donald R By wife	DNAI	Series A Preferred Stock	C - Conversion	I			-4.415		0
2015-07-21	2015-07-21	4	Parfet Donald R By Apjohn Ventures Fund, LP	DNAI	Series C Preferred Stock	C - Conversion	I			-24.277		0
2015-07-21	2015-07-21	4	Parfet Donald R By Apjohn Ventures Fund, LP	DNAI	Series C Preferred Stock	F - Taxes	I			-221		24.277
2015-07-21	2015-07-21	4	Parfet Donald R By Apjohn Ventures Fund, LP	DNAI	Series C Preferred Stock	X - Other	I			719		24.498
2015-07-21	2015-07-21	4	Parfet Donald R By Apjohn Ventures Fund, LP	DNAI	Series C Preferred Stock Warrant (right to buy)	X - Other	I		5,2150	-719	-4	0
2015-07-21	2015-07-21	4	Parfet Donald R By Apjohn Ventures Fund, LP	DNAI	Series B-1 Preferred Stock	C - Conversion	I			-516.203		0
2015-07-21	2015-07-21	4	Parfet Donald R By Apjohn Ventures Fund, LP	DNAI	Series B-1 Preferred Stock	F - Taxes	I			-2.941		516.203
2015-07-21	2015-07-21	4	Parfet Donald R By Apjohn Ventures Fund, LP	DNAI	Series B-1 Preferred Stock	X - Other	I			6.711		519.144
2015-07-21	2015-07-21	4	Parfet Donald R By Apjohn Ventures Fund, LP	DNAI	Series B-1 Preferred Stock Warrant (right to buy)	X - Other	I		7,4500	-6.711	-50	0
2015-07-21	2015-07-21	4	Parfet Donald R By Apjohn Ventures Fund, LP	DNAI	Series B-1 Preferred Stock	F - Taxes	I			-40.729		512.433
2015-07-21	2015-07-21	4	Parfet Donald R y Apjohn Ventures Fund, LP	DNAI	Series B-1 Preferred Stock	X - Other	I			265.536		553.162
2015-07-21	2015-07-21	4	Parfet Donald R By Apjohn Ventures Fund, LP	DNAI	Series B-1 Preferred Stock Warrant (right to buy)	X - Other	I		2,6080	-265.536	-693	0
2015-07-21	2015-07-21	4	Parfet Donald R By Apjohn Ventures Fund, LP	DNAI	Series B Preferred Stock	C - Conversion	I			-153.485		0
2015-07-21	2015-07-21	4	Parfet Donald R By Apjohn Ventures Fund, LP	DNAI	Series A Preferred Stock	C - Conversion	I			-26.728		0
2015-07-21	2015-07-21	4	Parfet Donald R By Apjohn Ventures Annex Fund LP	DNAI	Series D Preferred Stock	C - Conversion	I			-11.505		0
2015-07-21	2015-07-21	4	Parfet Donald R By Apjohn Ventures Annex Fund LP	DNAI	Series C Preferred Stock	C - Conversion	I			-59.225		0
2015-07-21	2015-07-21	4	Parfet Donald R By Apjohn Ventures Annex Fund LP	DNAI	Series B-1 Preferred Stock	C - Conversion	I			-67.112		0
2015-07-21	2015-07-21	4	Parfet Donald R By Apjohn Group, LLC	DNAI	Series A Preferred Stock	C - Conversion	I			-307		0
2015-07-21	2015-07-21	4	Parfet Donald R By Palmero Group LLC	DNAI	Common Stock	J - Other	I		5,2150	819	4		65.779
2015-07-21	2015-07-21	4	Parfet Donald R By Palmero Group LLC	DNAI	Common Stock	C - Conversion	I			13.130			64.960
2015-07-21	2015-07-21	4	Parfet Donald R By Palmero Group LLC	DNAI	Common Stock	C - Conversion	I			51.830			51.830
2015-07-21	2015-07-21	4	Parfet Donald R By Donald R. Parfet 2006 Trust, Dated May 1, 2006	DNAI	Common Stock	C - Conversion	I			142.422			353.802
2015-07-21	2015-07-21	4	Parfet Donald R By Donald R. Parfet 2006 Trust, Dated May 1, 2006	DNAI	Common Stock	C - Conversion	I			211.036			211.380
2015-07-21	2015-07-21	4	Parfet Donald R By Donald R. Parfet 2006 Trust, Dated May 1, 2006	DNAI	Common Stock	C - Conversion	I			344			344
2015-07-21	2015-07-21	4	Parfet Donald R By Ann VanDeWater Parfet 2006 Revocable Trust, Dated May 5, 2006	DNAI	Common Stock	J - Other	I		5,2150	4.119	21		217.903
2015-07-21	2015-07-21	4	Parfet Donald R By Ann VanDeWater Parfet 2006 Revocable Trust, Dated May 5, 2006	DNAI	Common Stock	C - Conversion	I			65.938			213.784
2015-07-21	2015-07-21	4	Parfet Donald R By Ann VanDeWater Parfet 2006 Revocable Trust, Dated May 5, 2006	DNAI	Common Stock	C - Conversion	I			121.242			147.846
2015-07-21	2015-07-21	4	Parfet Donald R By Ann VanDeWater Parfet 2006 Revocable Trust, Dated May 5, 2006	DNAI	Common Stock	C - Conversion	I			26.604			26.604
2015-07-21	2015-07-21	4	Parfet Donald R By wife	DNAI	Common Stock	C - Conversion	I			4.970			4.970
2015-07-21	2015-07-21	4	Parfet Donald R By Apjohn Ventures Fund, LP	DNAI	Common Stock	J - Other	I		5,2150	1.552	8		770.045
2015-07-21	2015-07-21	4	Parfet Donald R By Apjohn Ventures Fund, LP	DNAI	Common Stock	C - Conversion	I			24.277			768.493
2015-07-21	2015-07-21	4	Parfet Donald R By Apjohn Ventures Fund, LP	DNAI	Common Stock	C - Conversion	I			516.203			744.216
2015-07-21	2015-07-21	4	Parfet Donald R By Apjohn Ventures Fund, LP	DNAI	Common Stock	C - Conversion	I			170.538			228.013
2015-07-21	2015-07-21	4	Parfet Donald R By Apjohn Ventures Fund, LP	DNAI	Common Stock	C - Conversion	I			30.093			57.475
2015-07-21	2015-07-21	4	Parfet Donald R By Apjohn Ventures Annex Fund LP	DNAI	Common Stock	J - Other	I		5,2150	4.413	23		142.255
2015-07-21	2015-07-21	4	Parfet Donald R By Apjohn Ventures Annex Fund LP	DNAI	Common Stock	C - Conversion	I			11.505			137.842
2015-07-21	2015-07-21	4	Parfet Donald R By Apjohn Ventures Annex Fund LP	DNAI	Common Stock	C - Conversion	I			59.225			126.337
2015-07-21	2015-07-21	4	Parfet Donald R By Apjohn Ventures Annex Fund LP	DNAI	Common Stock	C - Conversion	I			67.112			67.112
2015-07-21	2015-07-21	4	Parfet Donald R By Apjohn Group, LLC	DNAI	Common Stock	C - Conversion	I			345			589
2015-07-21	2015-07-21	4	VIVO VENTURES VII, LLC By Vivo Ventures VII Affiliates Fund, L.P.	DNAI	Series D Preferred Stock	C - Conversion	I			-44.991		0
2015-07-21	2015-07-21	4	VIVO VENTURES VII, LLC By Vivo Ventures Fund VII, L.P.	DNAI	Series D Preferred Stock	C - Conversion	I			-2.064.308		0
2015-07-21	2015-07-21	4	VIVO VENTURES VII, LLC By Vivo Ventures VII Affiliates Fund, L.P.	DNAI	Common Stock	P - Purchase	I		17,0000	4.693	80		2.438.270
2015-07-21	2015-07-21	4	VIVO VENTURES VII, LLC By Vivo Ventures Fund VII, L.P.	DNAI	Common Stock	P - Purchase	I		17,0000	215.307	3.660		2.433.577
2015-07-21	2015-07-21	4	VIVO VENTURES VII, LLC By Vivo Ventures VII Affiliates Fund, L.P.	DNAI	Common Stock	J - Other	I		5,2150	2.324	12		2.218.270
2015-07-21	2015-07-21	4	VIVO VENTURES VII, LLC By Vivo Ventures Fund VII, L.P.	DNAI	Common Stock	J - Other	I		5,2150	106.647	556		2.215.946
2015-07-21	2015-07-21	4	VIVO VENTURES VII, LLC By Vivo Ventures VII Affiliates Fund, L.P.	DNAI	Common Stock	C - Conversion	I			44.991			2.109.299
2015-07-21	2015-07-21	4	VIVO VENTURES VII, LLC By Vivo Ventures Fund VII, L.P.	DNAI	Common Stock	C - Conversion	I			2.064.308			2.064.308
2015-07-21	2015-07-21	4	CHA ALBERT By Vivo Ventures VII Affiliates Fund, L.P.	DNAI	Series D Preferred Stock	C - Conversion	I			-44.991		0
2015-07-21	2015-07-21	4	CHA ALBERT By Vivo Ventures Fund VII, L.P.	DNAI	Series D Preferred Stock	C - Conversion	I			-2.064.308		0
2015-07-21	2015-07-21	4	CHA ALBERT By Vivo Ventures VII Affiliates Fund, L.P.	DNAI	Common Stock	P - Purchase	I		17,0000	4.693	80		2.438.270
2015-07-21	2015-07-21	4	CHA ALBERT By Vivo Ventures Fund VII, L.P.	DNAI	Common Stock	P - Purchase	I		17,0000	215.307	3.660		2.433.577
2015-07-21	2015-07-21	4	CHA ALBERT By Vivo Ventures VII Affiliates Fund, L.P.	DNAI	Common Stock	J - Other	I		5,2150	2.324	12		2.218.270
2015-07-21	2015-07-21	4	CHA ALBERT By Vivo Ventures Fund VII, L.P.	DNAI	Common Stock	J - Other	I		5,2150	106.647	556		2.215.946
2015-07-21	2015-07-21	4	CHA ALBERT By Vivo Ventures VII Affiliates Fund, L.P.	DNAI	Common Stock	C - Conversion	I			44.991			2.109.299
2015-07-21	2015-07-21	4	CHA ALBERT By Vivo Ventures Fund VII, L.P.	DNAI	Common Stock	C - Conversion	I			2.064.308			2.064.308
2015-07-21	2015-07-21	4	ORBIMED ADVISORS LLC See Footnotes	DNAI	Series D Preferred Stock	C - Conversion	I			-1.725.790		0
2015-07-21	2015-07-21	4	ORBIMED ADVISORS LLC See Footnotes	DNAI	Common Stock	P - Purchase	I		17,0000	175.000	2.975		1.989.949
2015-07-21	2015-07-21	4	ORBIMED ADVISORS LLC See Footnotes	DNAI	Common Stock	J - Other	I		5,2150	89.159	465		1.814.949
2015-07-21	2015-07-21	4	ORBIMED ADVISORS LLC See Footnotes	DNAI	Common Stock	C - Conversion	I			1.725.790			1.725.790
2015-07-15		3	You Angie	DNAI	Common Stock		D						206.504
2015-07-15		3	You Angie	DNAI	Common Stock		D						206.504
2015-07-15		3	Rodigueza Wendi	DNAI	Common Stock		D						314.620
2015-07-15		3	Rodigueza Wendi	DNAI	Common Stock		D						314.620
2015-07-15		3	Messmann Richard A	DNAI	Common Stock		D						80.104
2015-07-15		3	Messmann Richard A	DNAI	Common Stock		D						80.104
2015-07-15		3	Lovejoy Chandra D	DNAI	Common Stock		D						26.844
2015-07-15		3	Lovejoy Chandra D	DNAI	Common Stock		D						26.844
2015-07-15		3	Parfet Donald R By Apjohn Group, LLC	DNAI	Common Stock		I						97.718
2015-07-15		3	Parfet Donald R By Apjohn Ventures Fund, LP	DNAI	Common Stock		I						124.856
2015-07-15		3	Parfet Donald R By Apjohn Ventures Fund, LP	DNAI	Common Stock		I						124.856
2015-07-15		3	Parfet Donald R By Apjohn Group, LLC	DNAI	Common Stock		I						97.718
2015-07-15		3	Parfet Donald R	DNAI	Common Stock		D						167.322
2015-07-15		3	Parfet Donald R	DNAI	Common Stock		D						167.322

Offener Markt oder privater Kauf von nicht-derivativen oder derivativen Wertpapieren

Freiverkauf oder privater Verkauf von nicht-derivativen oder derivativen Wertpapieren

Gewährung, Vergabe oder sonstiger Erwerb von Wertpapieren des Unternehmens (z. B. eine Option)

Umwandlung von Derivaten

Verkauf oder Rückübertragung von Wertpapieren an das Unternehmen

Zahlung des Ausübungspreises oder der Steuerschuld mit einem Teil der vom Unternehmen erhaltenen Wertpapiere

Schenkung von Wertpapieren durch oder an den Insider

Aktien-Swaps und ähnliche Absicherungstransaktionen

Ausübung oder Umwandlung eines vom Unternehmen erhaltenen derivativen Wertpapiers (z. B. einer Option)

Eine freiwillig auf Formular 4 gemeldete Transaktion

Sonstige (mit einer Fußnote zur Beschreibung der Transaktion)

SRRA / Sierra Oncology Inc - Insider Trading and Ownership Report - SEC Form 3, 4, 5