Ionis Pharmaceuticals, Inc.
US ˙ NasdaqGS ˙ US4622221004

Einführung

Diese Seite bietet eine umfassende Analyse des bekannten Insiderhandels von Joseph Iii Klein. Insider sind leitende Angestellte, Direktoren oder bedeutende Investoren in einem Unternehmen. Es ist für Insider illegal, auf der Grundlage bestimmter, nicht öffentlicher Informationen mit ihren Unternehmen zu handeln. Das bedeutet nicht, dass es für sie illegal ist, irgendwelche Geschäfte in ihren eigenen Unternehmen zu tätigen. Sie müssen jedoch alle Geschäfte der SEC über ein Formular 4 melden. Trotz dieser Einschränkungen deuten akademische Untersuchungen darauf hin, dass Insider im Allgemeinen dazu neigen, den Markt in ihren eigenen Unternehmen zu übertreffen.

Durchschnittliche Handelsrentabilität

Die durchschnittliche Handelsrentabilität ist die durchschnittliche Rendite aller offenen Marktkäufe, die der Insider in den letzten drei Jahren getätigt hat. Um dies zu berechnen, untersuchen wir jeden ungeplanten Kauf, den der Insider auf dem offenen Markt getätigt hat, mit Ausnahme aller Geschäfte, die als Teil eines 10b5-1-Handelsplans gekennzeichnet waren. Anschließend berechnen wir die durchschnittliche Performance dieser Geschäfte über 3, 6 und 12 Monate, wobei wir für jeden dieser Zeiträume den Durchschnitt bilden, um eine endgültige Performance-Kennzahl für jedes Geschäft zu erhalten. Schließlich berechnen wir den Durchschnitt aller Performance-Metriken, um eine Performance-Metrik für den Insider zu ermitteln. Diese Liste enthält nur Insider, die in den letzten zwei Jahren mindestens drei Geschäfte getätigt haben.

Wenn die Handelsrentabilität dieses Insiders "N/A" ist, hat er entweder in den letzten drei Jahren keine Käufe auf dem freien Markt getätigt, oder die von ihm getätigten Geschäfte sind zu kurz her, um eine zuverlässige Performance-Kennzahl zu berechnen.

Aktualisierungshäufigkeit: Täglich

Liste der profitabelsten Insider-Händler ansehen.

Unternehmen mit gemeldeten Insiderpositionen

Aus den SEC-Filings geht hervor, dass Joseph Iii Klein Beteiligungen an den folgenden Unternehmen gemeldet oder mit ihnen gehandelt hat:

Wertpapier Titel Letzte gemeldete Beteiligungen
US:IONS / Ionis Pharmaceuticals, Inc. Director 11.014
Director 0
US:US69329YAJ38 / Pdl Biopharma Inc Bond Director 16.983
So interpretieren Sie die Diagramme

Die folgenden Diagramme zeigen die Wertentwicklung von Wertpapieren nach jedem offenen, nicht geplanten Handel von Joseph Iii Klein. Nicht geplante Geschäfte sind Geschäfte, die nicht im Rahmen eines 10b5-1-Handelsplans getätigt wurden. Die Aktienperformance wird als kumulative prozentuale Veränderung des Aktienkurses dargestellt. Wenn beispielsweise am 1. Januar 2019 ein Insiderhandel getätigt wurde, zeigt das Diagramm die tägliche prozentuale Veränderung des Wertpapiers bis zum heutigen Tag. Wenn der Aktienkurs in dieser Zeit von $10 auf $15 gestiegen ist, beträgt die kumulative prozentuale Veränderung des Aktienkurses 50 %. Eine Kursveränderung von $10 auf $20 würde 100% betragen und eine Kursveränderung von $10 auf $5 wäre -50%.

Letztendlich versuchen wir festzustellen, wie eng die Geschäfte des Insiders mit den (positiven oder negativen) Überschussrenditen des Aktienkurses korrelieren, um zu sehen, ob der Insider seine Geschäfte zeitlich so abstimmt, dass er von Insiderinformationen profitiert. Stellen Sie sich die Situation vor, dass ein Insider dies tun würde. In dieser Situation würden wir entweder (a) positive Renditen nach Käufen oder (b) negative Renditen nach Verkäufen erwarten. Im Falle von (a) würde das KAUF-Diagramm eine Reihe von aufwärts gerichteten Kurven zeigen, die auf positive Renditen nach jeder Kauftransaktion hinweisen. Im Falle von (b) würde das VERKAUFS-Diagramm eine Reihe von abwärts gerichteten Kurven zeigen, die auf negative Renditen nach jeder Verkaufstransaktion hinweisen.

Dies allein reicht jedoch nicht aus, um Schlussfolgerungen zu ziehen. Wenn sich der Aktienkurs des Unternehmens beispielsweise über viele Jahre hinweg in einem nicht-zyklischen Aufwärtstrend befand, dann würden wir erwarten, dass alle Nach-Kauf-Kurven aufwärts gerichtet sind. Ebenso würden nicht-zyklische Rückgänge über viele Jahre hinweg zu abwärts geneigten Nachhandelsdiagrammen führen. Keines dieser Diagramme würde auf Insiderhandel hindeuten.

Der stärkste Indikator wäre eine Situation, in der der Aktienkurs extrem zyklisch war und es sowohl positive Signale im KAUF-Chart als auch negative im VERKAUF-Chart gab. Diese Situation würde stark auf einen Insider hindeuten, der das Timing von Geschäften zu seinem finanziellen Vorteil nutzt.

Insiderkäufe IONS / Ionis Pharmaceuticals, Inc. - Kurzfristige Gewinnanalyse

In diesem Abschnitt analysieren wir die Rentabilität jedes ungeplanten Insiderkaufs, der auf dem freien Markt in IONS / Ionis Pharmaceuticals, Inc. getätigt wurde. Diese Analyse hilft zu verstehen, ob der Insider beständig abnormale Renditen erzielt und es sich lohnt, ihm zu folgen. Diese Analyse bezieht sich auf ein Jahr nach jedem Handel, und die Ergebnisse sind theoretisch.

Die folgende Tabelle zeigt die jüngsten Käufe am offenen Markt, die nicht Teil eines automatischen Handelsplans waren.

Handelsdatum Ticker Insider Berichtete
Aktien
Berichteter
Preis
Angepasste
Aktien
Angepasster
Preis
Kostenbasis Tage bis
Max
Preis bei
Max
Max
Gewinn ($)
Max Rendite (%)
Für diese Insider- und Wertpapierkombination sind keine ungeplanten Open-Market-Trades bekannt

Angepasster Preis ist der an den Split angepasste Preis. Angepasste Aktien ist die an den Split angepasste Anzahl der Aktien.

IONS / Ionis Pharmaceuticals, Inc. Insider Trades
Insiderverkäufe IONS / Ionis Pharmaceuticals, Inc. - Kurzfristige Verlustanalyse

In diesem Abschnitt analysieren wir die kurzfristige Verlustvermeidung jedes ungeplanten Insider-Verkaufs auf dem freien Markt in IONS / Ionis Pharmaceuticals, Inc.. Ein konsistentes Muster der Verlustvermeidung kann darauf hindeuten, dass zukünftige Verkaufstransaktionen Kursrückgänge vorhersagen können. Diese Analyse bezieht sich auf ein Jahr nach jedem Handel und die Ergebnisse sind theoretisch.

Die folgende Tabelle zeigt die jüngsten Verkäufe am offenen Markt, die nicht Teil eines automatischen Handelsplans waren.

Handelsdatum Ticker Insider Berichtete
Aktien
Berichteter
Preis
Angepasste
Aktien
Angepasster
Preis
Kostenbasis Tage bis
Min
Preis bei
Min
Max Verlust
Vermieden ($)
Max. Verlust
Vermieden (%)
2024-05-03 IONS KLEIN JOSEPH III 1.318 42,5721 1.318 42,5721 56.110 340 25.5100 -22.488 -40,08
2024-05-03 IONS KLEIN JOSEPH III 682 42,9449 682 42,9449 29.288
2024-05-03 IONS KLEIN JOSEPH III 1.269 42,5875 1.269 42,5875 54.044
2024-05-03 IONS KLEIN JOSEPH III 731 42,9767 731 42,9767 31.416
2024-05-03 IONS KLEIN JOSEPH III 1.070 42,5473 1.070 42,5473 45.526
2024-05-03 IONS KLEIN JOSEPH III 930 42,8957 930 42,8957 39.893
2015-11-11 ISIS KLEIN JOSEPH III 3.750 64,1795 3.750 64,1795 240.673
2015-11-11 ISIS KLEIN JOSEPH III 3.125 64,1795 3.125 64,1795 200.561
2015-03-05 ISIS KLEIN JOSEPH III 7.000 70,9545 7.000 70,9545 496.682
2014-01-24 ISIS KLEIN JOSEPH III 7.500 48,6797 7.500 48,6797 365.098
2014-01-24 ISIS KLEIN JOSEPH III 2.813 48,6102 2.813 48,6102 136.740
2013-11-25 ISIS KLEIN JOSEPH III 6.000 36,8594 6.000 36,8594 221.156
2013-08-09 ISIS KLEIN JOSEPH III 103 28,2300 103 28,2300 2.908
2013-08-09 ISIS KLEIN JOSEPH III 3.647 28,2200 3.647 28,2200 102.918
2013-08-09 ISIS KLEIN JOSEPH III 7.500 28,2200 7.500 28,2200 211.650
2013-08-09 ISIS KLEIN JOSEPH III 7.500 28,2200 7.500 28,2200 211.650

Angepasster Preis ist der an den Split angepasste Preis. Angepasste Aktien ist die an den Split angepasste Anzahl der Aktien.

IONS / Ionis Pharmaceuticals, Inc. Insider Trades
Geschichte des Insiderhandels

Diese Tabelle zeigt die vollständige Liste der von Joseph Iii Klein getätigten Insidergeschäfte, die der Securities Exchange Commission (SEC) gemeldet wurden.

Datum der Einreichung Tran Datum Form Ticker Wertpapier Code 10b5-1 Aktien Verbleibende Aktien Prozent
Änderung
Aktie
Preis
Tran
Wert
Verbleibender
Wert
2026-05-05 2026-05-01 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X -1.431 11.014 -11,50 74,45 -106.534 819.964
2026-05-05 2026-05-01 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X -8.680 12.445 -41,09 73,35 -636.704 912.878
2026-05-05 2026-05-01 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise 10.111 21.125 91,80 47,11 476.329 995.199
2026-04-02 2026-04-01 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X -2.216 11.014 -16,75 75,95 -168.314 836.557
2026-04-02 2026-04-01 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X -20.105 13.230 -60,31 75,50 -1.517.988 998.905
2026-04-02 2026-04-01 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise 10.321 33.335 44,85 41,08 423.987 1.369.402
2026-04-02 2026-04-01 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise 12.000 23.014 108,95 38,06 456.720 875.913
2026-03-05 2026-03-03 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X -1.012 11.014 -8,42 80,82 -81.788 890.129
2026-03-05 2026-03-03 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X -6.794 12.026 -36,10 80,00 -543.486 962.020
2026-03-05 2026-03-03 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X -13.526 18.820 -41,82 79,17 -1.070.908 1.490.055
2026-03-05 2026-03-03 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise 4.000 32.346 14,11 42,88 171.520 1.386.996
2026-03-05 2026-03-03 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise 12.000 28.346 73,41 40,05 480.600 1.135.257
2025-11-28 2025-11-25 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X -4.000 0 -100,00 80,00 -320.000
2025-11-28 2025-11-25 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X -4.000 0 -100,00 80,00 -320.000
2025-11-28 2025-11-25 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X -4.000 0 -100,00 80,00 -320.000
2025-11-28 2025-11-25 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise 4.000 4.000
2025-11-28 2025-11-25 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise 4.000 4.000
2025-11-28 2025-11-25 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise 4.000 4.000
2025-09-04 2025-09-03 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X -28.000 0 -100,00 60,00 -1.680.000
2025-09-04 2025-09-03 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise 12.000 28.000 75,00
2025-09-04 2025-09-03 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise 16.000 16.000
2025-09-04 2025-09-03 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X -28.000 0 -100,00 60,00 -1.680.000
2025-09-04 2025-09-03 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise 12.000 28.000 75,00
2025-09-04 2025-09-03 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise 16.000 16.000
2024-07-17 2024-07-16 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X -12.000 0 -100,00 50,00 -600.000
2024-07-17 2024-07-16 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise 12.000 12.000 24,42 293.040 293.040
2024-05-07 2024-05-03 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale -930 0 -100,00 42,90 -39.893
2024-05-07 2024-05-03 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale -1.070 930 -53,50 42,55 -45.526 39.569
2024-05-07 2024-05-03 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale -731 2.000 -26,77 42,98 -31.416 85.953
2024-05-07 2024-05-03 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale -1.269 2.731 -31,72 42,59 -54.044 116.306
2024-05-07 2024-05-03 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale -682 4.000 -14,57 42,94 -29.288 171.780
2024-05-07 2024-05-03 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale -1.318 4.682 -21,97 42,57 -56.110 199.323
2023-11-17 2023-11-15 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X -2.000 16.346 -10,90 50,00 -100.000 817.300
2023-09-28 2023-09-26 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X -2.000 18.346 -9,83 45,13 -90.254 827.896
2023-07-19 2023-07-18 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X -3.555 20.346 -14,87 42,00 -149.310 854.532
2023-07-19 2023-07-17 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise 5.333 23.901 28,72
2023-07-19 2023-07-17 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise 1.777 18.568 10,58
2023-01-18 2023-01-17 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X -2.000 16.791 -10,64 40,00 -80.000 671.640
2022-07-19 2022-07-15 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X -644 18.791 -3,31 38,78 -24.974 728.715
2022-07-19 2022-07-15 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X -689 19.435 -3,42 37,74 -26.003 733.477
2022-07-19 2022-07-15 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise 2.665 20.124 15,26
2022-07-19 2022-07-15 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise 5.333 17.459 43,98
2022-02-14 2021-11-30 5 IONS IONIS PHARMACEUTICALS INC
Non-Qualified Stock Option (right to buy)
G - Gift 8.000 8.000
2022-02-14 2021-11-30 5 IONS IONIS PHARMACEUTICALS INC
Non-Qualified Stock Option (right to buy)
G - Gift 12.000 12.000
2022-02-14 2021-11-30 5 IONS IONIS PHARMACEUTICALS INC
Non-Qualified Stock Option (right to buy)
G - Gift 12.000 12.000
2022-02-14 2021-11-30 5 IONS IONIS PHARMACEUTICALS INC
Non-Qualified Stock Option (right to buy)
G - Gift 16.000 16.000
2022-02-14 2021-11-30 5 IONS IONIS PHARMACEUTICALS INC
Non-Qualified Stock Option (right to buy)
G - Gift 16.000 16.000
2022-02-14 2021-11-30 5 IONS IONIS PHARMACEUTICALS INC
Non-Qualified Stock Option (right to buy)
G - Gift 12.000 12.000
2022-02-14 2021-11-30 5 IONS IONIS PHARMACEUTICALS INC
Non-Qualified Stock Option (right to buy)
G - Gift -8.000 8.000 -50,00
2022-02-14 2021-11-30 5 IONS IONIS PHARMACEUTICALS INC
Non-Qualified Stock Option (right to buy)
G - Gift -12.000 0 -100,00
2022-02-14 2021-11-30 5 IONS IONIS PHARMACEUTICALS INC
Non-Qualified Stock Option (right to buy)
G - Gift -12.000 0 -100,00
2022-02-14 2021-11-30 5 IONS IONIS PHARMACEUTICALS INC
Non-Qualified Stock Option (right to buy)
G - Gift -16.000 0 -100,00
2022-02-14 2021-11-30 5 IONS IONIS PHARMACEUTICALS INC
Non-Qualified Stock Option (right to buy)
G - Gift -16.000 0 -100,00
2022-02-14 2021-11-30 5 IONS IONIS PHARMACEUTICALS INC
Non-Qualified Stock Option (right to buy)
G - Gift -12.000 4.000 -75,00
2022-02-14 2021-11-30 5 IONS IONIS PHARMACEUTICALS INC
Common Stock
G - Gift 6.000 6.000
2022-02-14 2021-11-30 5 IONS IONIS PHARMACEUTICALS INC
Common Stock
G - Gift -6.000 12.126 -33,10
2021-07-19 2021-07-15 4 IONS IONIS PHARMACEUTICALS INC
Restricted Stock Unit
M - Exercise -1.778 9.775 -15,39
2021-07-19 2021-07-15 4 IONS IONIS PHARMACEUTICALS INC
Restricted Stock Unit
M - Exercise -666 11.553 -5,45
2021-07-19 2021-07-15 4 IONS IONIS PHARMACEUTICALS INC
Restricted Stock Unit
M - Exercise -889 12.219 -6,78
2021-07-19 2021-07-15 4 IONS IONIS PHARMACEUTICALS INC
Restricted Stock Unit
M - Exercise -5.333 13.108 -28,92
2021-07-19 2021-07-15 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X -4.334 18.126 -19,30 35,30 -152.989 639.844
2021-07-19 2021-07-15 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise 1.778 22.460 8,60
2021-07-19 2021-07-15 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise 666 20.682 3,33
2021-07-19 2021-07-15 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise 889 20.016 4,65
2021-07-19 2021-07-15 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise 5.333 19.127 38,66
2021-07-06 2021-07-01 4 IONS IONIS PHARMACEUTICALS INC
Restricted Stock Unit
A - Award 5.333 18.441 40,69
2021-07-06 2021-07-01 4 IONS IONIS PHARMACEUTICALS INC
Non-Qualified Stock Option (right to buy)
A - Award 12.000 12.000
2020-10-22 2020-10-20 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X -2.889 13.794 -17,32 46,86 -135.386 646.421
2020-10-13 2020-10-12 4 AKCA AKCEA THERAPEUTICS, INC.
Stock Option (right to buy)
D - Sale to Issuer -26.400 0 -100,00 2,01 -53.064
2020-07-06 2020-07-06 4 IONS IONIS PHARMACEUTICALS INC
Restricted Stock Units
M - Exercise -667 666 -50,04
2020-07-06 2020-07-06 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise 667 16.683 4,16
2020-07-06 2020-07-02 4 IONS IONIS PHARMACEUTICALS INC
Restricted Stock Units
M - Exercise -889 1.777 -33,35
2020-07-06 2020-07-02 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise 889 16.016 5,88
2020-07-06 2020-07-01 4 IONS IONIS PHARMACEUTICALS INC
Director Stock Option (right to buy)
A - Award 12.000 12.000
2020-07-06 2020-07-01 4 IONS IONIS PHARMACEUTICALS INC
Restricted Stock Units
A - Award 5.333 5.333
2020-07-06 2020-07-01 4 IONS IONIS PHARMACEUTICALS INC
Restricted Stock Units
M - Exercise -1.778 5.332 -25,01
2020-07-06 2020-07-01 4 IONS IONIS PHARMACEUTICALS INC
Restricted Stock Units
M - Exercise -666 0 -100,00
2020-07-06 2020-07-01 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise 1.778 15.127 13,32
2020-07-06 2020-07-01 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise 666 13.349 5,25
2020-04-15 2020-04-13 4 AKCA AKCEA THERAPEUTICS, INC.
Stock Option (right to buy)
A - Award 26.400 26.400
2019-12-23 2019-12-23 4 IONS IONIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise -1.000 0 -100,00
2019-12-23 2019-12-23 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X -1.000 12.683 -7,31 61,87 -61.874 784.750
2019-12-23 2019-12-23 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 1.000 13.683 7,88 35,53 35.530 486.157
2019-12-18 2019-12-16 4 IONS IONIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise -1.000 1.000 -50,00
2019-12-18 2019-12-16 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X -1.000 12.683 -7,31 65,45 -65.446 830.058
2019-12-18 2019-12-16 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 1.000 13.683 7,88 35,53 35.530 486.157
2019-12-10 2019-12-09 4 IONS IONIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise -1.000 2.000 -33,33
2019-12-10 2019-12-09 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X -1.000 12.683 -7,31 63,74 -63.745 808.474
2019-12-10 2019-12-09 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 1.000 13.683 7,88 35,53 35.530 486.157
2019-12-04 2019-12-02 4 IONS IONIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise -1.000 3.000 -25,00
2019-12-04 2019-12-02 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X -1.000 12.683 -7,31 64,08 -64.083 812.765
2019-12-04 2019-12-02 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 1.000 13.683 7,88 35,53 35.530 486.157
2019-11-26 2019-11-25 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X -812 12.683 -6,02 62,90 -51.075 797.761
2019-11-21 2019-11-20 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X -2.000 13.495 -12,91 60,00 -120.000 809.700
2019-09-23 2019-09-20 4 AKCA AKCEA THERAPEUTICS, INC.
Stock Option (right to buy)
A - Award 53.000 53.000
2019-07-03 2019-07-03 4 IONS IONIS PHARMACEUTICALS INC
Restricted Stock Units
M - Exercise -667 1.333 -33,35
2019-07-03 2019-07-03 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise 667 15.495 4,50
2019-07-03 2019-07-02 4 IONS IONIS PHARMACEUTICALS INC
Restricted Stock Units
M - Exercise -889 2.666 -25,01
2019-07-03 2019-07-02 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise 889 14.828 6,38
2019-07-03 2019-07-01 4 IONS IONIS PHARMACEUTICALS INC
Director Stock Option (right to buy)
A - Award 16.000 16.000
2019-07-03 2019-07-01 4 IONS IONIS PHARMACEUTICALS INC
Restricted Stock Units
A - Award 7.110 7.110
2019-07-03 2019-07-01 4 IONS IONIS PHARMACEUTICALS INC
Restricted Stock Units
M - Exercise -667 666 -50,04
2019-07-03 2019-07-01 4 IONS IONIS PHARMACEUTICALS INC
Restricted Stock Units
M - Exercise -666 0 -100,00
2019-07-03 2019-07-01 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise 667 13.939 5,03
2019-07-03 2019-07-01 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise 666 13.272 5,28
2018-07-03 2018-07-03 4 IONS IONIS PHARMACEUTICALS INC
Restricted Stock Units
M - Exercise -667 2.000 -25,01
2018-07-03 2018-07-03 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise 667 12.606 5,59
2018-07-03 2018-07-02 4 IONS IONIS PHARMACEUTICALS INC
Director Stock Option (right to buy)
A - Award 16.000 16.000
2018-07-03 2018-07-02 4 IONS IONIS PHARMACEUTICALS INC
Restricted Stock Units
A - Award 3.555 3.555
2018-07-03 2018-07-01 4 IONS IONIS PHARMACEUTICALS INC
Restricted Stock Units
M - Exercise -2.000 1.999 -50,01
2018-07-03 2018-07-01 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise 2.000 11.939 20,12
2018-03-30 2018-03-29 4 IONS IONIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise 2.000 0 -100,00
2018-03-30 2018-03-29 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X -2.000 9.939 -16,75 46,15 -92.300 458.685
2018-03-30 2018-03-29 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 2.000 11.939 20,12 24,42 48.840 291.550
2018-03-16 2018-03-15 4 IONS IONIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise 2.000 2.000
2018-03-16 2018-03-15 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X -200 9.939 -1,97 52,11 -10.422 517.921
2018-03-16 2018-03-15 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 200 10.139 2,01 24,42 4.884 247.594
2018-03-16 2018-03-15 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X -900 9.939 -8,30 51,59 -46.431 512.753
2018-03-16 2018-03-15 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 900 10.839 9,06 24,42 21.978 264.688
2018-03-16 2018-03-15 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 900 10.839 9,06 24,42 21.978 264.688
2018-03-16 2018-03-15 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X -900 9.939 -8,30 50,45 -45.405 501.423
2018-03-01 2018-02-28 4 IONS IONIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise 3.000 0 -100,00
2018-03-01 2018-02-28 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X -2.100 9.939 -17,44 52,29 -109.809 519.710
2018-03-01 2018-02-28 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 2.100 12.039 21,13 35,53 74.613 427.746
2018-03-01 2018-02-28 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X -900 9.939 -8,30 51,02 -45.918 507.088
2018-03-01 2018-02-28 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 900 10.839 9,06 35,53 31.977 385.110
2018-02-16 2018-02-15 4 IONS IONIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise 3.000 3.000
2018-02-16 2018-02-15 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X -1.600 9.939 -13,87 49,20 -78.720 488.999
2018-02-16 2018-02-15 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 1.600 11.539 16,10 35,53 56.848 409.981
2018-02-16 2018-02-15 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X -1.400 9.939 -12,35 48,76 -68.264 484.626
2018-02-16 2018-02-15 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 1.400 11.339 14,09 35,53 49.742 402.875
2018-01-31 2018-01-30 4/A IONS IONIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise 3.000 6.000 100,00
2018-01-31 2018-01-30 4/A IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X -3.000 9.939 -23,19 52,86 -158.580 525.376
2018-01-31 2018-01-30 4/A IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 3.000 12.939 30,18 35,53 106.590 459.723
2018-01-17 2018-01-16 4 IONS IONIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise -3.000 9.000 -25,00
2018-01-17 2018-01-16 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X -1.400 9.939 -12,35 52,97 -74.158 526.469
2018-01-17 2018-01-16 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 1.400 11.339 14,09 35,53 49.742 402.875
2018-01-17 2018-01-16 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X -1.600 9.939 -13,87 52,13 -83.408 518.120
2018-01-17 2018-01-16 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 1.600 11.539 16,10 35,53 56.848 409.981
2018-01-02 2017-12-29 4 IONS IONIS PHARMACEUTICALS INC
Non-Employee Director Stock Option (right to buy)
M - Exercise -3.000 0 -100,00
2018-01-02 2017-12-29 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X -3.000 9.939 -23,19 50,56 -151.680 502.516
2018-01-02 2017-12-29 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 3.000 12.939 30,18 28,47 85.410 368.373
2017-12-19 2017-12-15 4 IONS IONIS PHARMACEUTICALS INC
NonEmployee Director stock option (right to buy)
M - Exercise -3.000 3.000 -50,00
2017-12-19 2017-12-15 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X -3.000 9.939 -23,19 51,69 -155.070 513.747
2017-12-19 2017-12-15 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 3.000 12.939 30,18 28,47 85.410 368.373
2017-12-01 2017-11-30 4 IONS IONIS PHARMACEUTICALS INC
Director Stock Option (right to buy)
M - Exercise -3.000 6.000 -33,33
2017-12-01 2017-11-30 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X -3.000 9.939 -23,19 53,55 -160.650 532.233
2017-12-01 2017-11-30 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 3.000 12.939 30,18 28,47 85.410 368.373
2017-11-17 2017-11-16 4 IONS IONIS PHARMACEUTICALS INC
Non-Employee Director Stock Option (right to buy)
M - Exercise -2.812 0 -100,00
2017-11-17 2017-11-16 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 2.812 9.939 39,46 12,94 36.387 128.611
2017-11-17 2017-11-15 4 IONS IONIS PHARMACEUTICALS INC
Non-Employee Director Stock Option (right to buy)
M - Exercise -2.250 9.000 -20,00
2017-11-17 2017-11-15 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X -2.250 7.127 -23,99 53,56 -120.510 381.722
2017-11-17 2017-11-15 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 2.250 9.377 31,57 28,47 64.058 266.963
2017-11-14 2017-11-13 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X -3.000 7.127 -29,62 55,39 -166.170 394.765
2017-07-03 2017-07-03 4 IONS IONIS PHARMACEUTICALS INC
Director Stock Option (right to buy)
A - Award 16.000 16.000
2017-07-03 2017-07-03 4 IONS IONIS PHARMACEUTICALS INC
Restricted Stock Units
A - Award 2.667 2.667
2017-07-03 2017-07-02 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise 2.469 10.127 32,24
2017-07-03 2017-07-01 4 IONS IONIS PHARMACEUTICALS INC
Restricted Stock Units
M - Exercise -2.469 3.999 -38,17
2016-07-06 2016-07-02 4 IONS IONIS PHARMACEUTICALS INC
Restricted Stock Units
M - Exercise -312 0 -100,00
2016-07-06 2016-07-02 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise 312 7.658 4,25
2016-07-06 2016-07-01 4 IONS IONIS PHARMACEUTICALS INC
Director Stock Option (right to buy)
A - Award 16.000 16.000
2016-07-06 2016-07-01 4 IONS IONIS PHARMACEUTICALS INC
Restricted Stock Units
A - Award 2.667 2.667
2016-07-06 2016-07-01 4 IONS IONIS PHARMACEUTICALS INC
Restricted Stock Units
M - Exercise -1.803 3.801 -32,17
2016-07-06 2016-07-01 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise 469 7.346 6,82
2016-07-06 2016-07-01 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise 667 6.877 10,74
2016-07-06 2016-07-01 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise 667 6.877 10,74
2015-11-12 2015-11-11 4 ISIS ISIS PHARMACEUTICALS INC
Director Stock Option (right to buy)
M - Exercise -3.125 2.812 -52,64
2015-11-12 2015-11-11 4 ISIS ISIS PHARMACEUTICALS INC
Director Stock Option (right to buy)
M - Exercise -3.750 0 -100,00
2015-11-12 2015-11-11 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale -3.125 5.543 -36,05 64,18 -200.561 355.747
2015-11-12 2015-11-11 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise 3.125 8.668 56,38 12,94 40.438 112.164
2015-11-12 2015-11-11 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale -3.750 5.543 -40,35 64,18 -240.673 355.747
2015-11-12 2015-11-11 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise 3.750 9.293 67,65 9,30 34.875 86.425
2015-07-02 2015-07-02 4 ISIS ISIS PHARMACEUTICALS INC
Restricted Stock Units
M - Exercise -312 312 -50,00
2015-07-02 2015-07-02 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise 312 5.543 5,96
2015-07-02 2015-07-01 4 ISIS ISIS PHARMACEUTICALS INC
Director Stock Option (right to buy)
A - Award 16.000 16.000
2015-07-02 2015-07-01 4 ISIS ISIS PHARMACEUTICALS INC
Restricted Stock Units
A - Award 2.667 2.667
2015-07-02 2015-07-01 4 ISIS ISIS PHARMACEUTICALS INC
Restricted Stock Units
M - Exercise -667 2.000 -25,01
2015-07-02 2015-07-01 4 ISIS ISIS PHARMACEUTICALS INC
Restricted Stock Units
M - Exercise -469 937 -33,36
2015-07-02 2015-07-01 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise 667 5.231 14,61
2015-07-02 2015-07-01 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise 469 4.564 11,45
2015-03-09 2015-03-05 4 ISIS ISIS PHARMACEUTICALS INC
Director Stock Option (right to buy)
M - Exercise -2.500 5.937 -29,63
2015-03-09 2015-03-05 4 ISIS ISIS PHARMACEUTICALS INC
Director Stock Option (right to buy)
M - Exercise -3.750 3.750 -50,00
2015-03-09 2015-03-05 4 ISIS ISIS PHARMACEUTICALS INC
Director Stock Option (right to buy)
M - Exercise -3.750 3.750 -50,00
2015-03-09 2015-03-05 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale -7.000 4.095 -63,09 70,95 -496.682 290.559
2015-03-09 2015-03-05 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise 2.500 11.095 29,09 12,94 32.350 143.569
2015-03-09 2015-03-05 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise 3.750 8.595 77,40 9,30 34.875 79.934
2015-03-09 2015-03-05 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise 3.750 4.845 342,47 9,22 34.575 44.671
2015-02-13 2015-02-11 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
G - Gift -2.000 1.095 -64,62
2014-07-02 2014-07-02 4 ISIS ISIS PHARMACEUTICALS INC
Restricted Stock Units
M - Exercise -313 624 -33,40
2014-07-02 2014-07-02 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise 313 3.095 11,25
2014-07-02 2014-07-01 4 ISIS ISIS PHARMACEUTICALS INC
Director Stock Option (right to buy)
A - Award 16.000 16.000
2014-07-02 2014-07-01 4 ISIS ISIS PHARMACEUTICALS INC
Restricted Stock Units
A - Award 2.667 2.667
2014-07-02 2014-07-01 4 ISIS ISIS PHARMACEUTICALS INC
Restricted Stock Units
M - Exercise -469 1.406 -25,01
2014-07-02 2014-07-01 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise 469 2.782 20,28
2014-01-24 2014-01-24 4 ISIS ISIS PHARMACEUTICALS INC
Director Stock Option (right to buy)
M - Exercise -2.813 8.437 -25,00
2014-01-24 2014-01-24 4 ISIS ISIS PHARMACEUTICALS INC
Director Stock Option (right to buy)
M - Exercise -7.500 0 -100,00
2014-01-24 2014-01-24 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale -2.813 2.313 -54,88 48,61 -136.740 112.435
2014-01-24 2014-01-24 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise 2.813 5.126 121,62 12,94 36.400 66.330
2014-01-24 2014-01-24 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale -7.500 2.313 -76,43 48,68 -365.098 112.596
2014-01-24 2014-01-24 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise 7.500 9.813 324,25 16,32 122.400 160.148
2013-11-27 2013-11-25 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale -6.000 2.313 -72,18 36,86 -221.156 85.256
2013-08-13 2013-08-09 4 ISIS ISIS PHARMACEUTICALS INC
Director Stock Option (right to buy)
M - Exercise -7.500 7.500 -50,00
2013-08-13 2013-08-09 4 ISIS ISIS PHARMACEUTICALS INC
Director Stock Option (right to buy)
M - Exercise -7.500 7.500 -50,00
2013-08-13 2013-08-09 4 ISIS ISIS PHARMACEUTICALS INC
Director Stock Option (right to buy)
M - Exercise -3.750 0 -100,00
2013-08-13 2013-08-09 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale -7.500 8.313 -47,43 28,22 -211.650 234.593
2013-08-13 2013-08-09 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale -7.500 8.313 -47,43 28,22 -211.650 234.593
2013-08-13 2013-08-09 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise 7.500 15.813 90,22 9,22 69.150 145.796
2013-08-13 2013-08-09 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise 7.500 15.813 90,22 9,30 69.750 147.061
2013-08-13 2013-08-09 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale -3.647 8.313 -30,49 28,22 -102.918 234.593
2013-08-13 2013-08-09 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise 3.647 11.960 43,87 13,88 50.620 166.005
2013-08-13 2013-08-09 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale -103 8.313 -1,22 28,23 -2.908 234.676
2013-08-13 2013-08-09 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise 103 8.416 1,24 13,88 1.430 116.814
2013-07-03 2013-07-02 4 ISIS ISIS PHARMACEUTICALS INC
Restricted Stock Units
M - Exercise -313 937 -25,04
2013-07-03 2013-07-02 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise 313 8.313 3,91
2013-07-03 2013-07-01 4 ISIS ISIS PHARMACEUTICALS INC
Restricted Stock Units
A - Award 1.875 1.875
2013-07-03 2013-07-01 4 ISIS ISIS PHARMACEUTICALS INC
Director Stock Option (right to buy)
A - Award 11.250 11.250
2013-03-21 2013-03-20 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X -174 0 -100,00 18,00 -3.132
2013-03-21 2013-03-20 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 174 174 5,93 1.032 1.032
2013-03-21 2013-03-20 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X -1.250 0 -100,00 18,00 -22.500
2013-03-21 2013-03-20 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 1.250 1.250 9,22 11.525 11.525
2013-03-21 2013-03-20 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X -2.500 0 -100,00 18,00 -45.000
2013-03-21 2013-03-20 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 2.500 2.500 16,32 40.800 40.800
2013-03-21 2013-03-20 4 ISIS ISIS PHARMACEUTICALS INC
Director Stock Option (right to buy)
M - Exercise -174 0 -100,00
2013-03-21 2013-03-20 4 ISIS ISIS PHARMACEUTICALS INC
Director Stock Option (right to buy)
M - Exercise -174 0 -100,00
2013-03-21 2013-03-20 4 ISIS ISIS PHARMACEUTICALS INC
Director Stock Option (right to buy)
M - Exercise -1.250 0 -100,00
2013-03-21 2013-03-20 4 ISIS ISIS PHARMACEUTICALS INC
Director Stock Option (right to buy)
M - Exercise -1.250 0 -100,00
2013-03-21 2013-03-20 4 ISIS ISIS PHARMACEUTICALS INC
Director Stock Option (right to buy)
M - Exercise -2.500 0 -100,00
2013-03-21 2013-03-20 4 ISIS ISIS PHARMACEUTICALS INC
Director Stock Option (right to buy)
M - Exercise -2.500 0 -100,00
2013-03-21 2013-03-20 4 ISIS ISIS PHARMACEUTICALS INC
Director Stock Option (right to buy)
M - Exercise -4.167 0 -100,00
2013-03-21 2013-03-20 4 ISIS ISIS PHARMACEUTICALS INC
Director Stock Option (right to buy)
M - Exercise -4.167 0 -100,00
2013-03-21 2013-03-20 4 ISIS ISIS PHARMACEUTICALS INC
Director Stock Option (right to buy)
M - Exercise -3.750 0 -100,00
2013-03-21 2013-03-20 4 ISIS ISIS PHARMACEUTICALS INC
Director Stock Option (right to buy)
M - Exercise -3.750 0 -100,00
2013-03-21 2013-03-20 4 ISIS ISIS PHARMACEUTICALS INC
Director Stock Option (right to buy)
M - Exercise -1.250 0 -100,00
2013-03-21 2013-03-20 4 ISIS ISIS PHARMACEUTICALS INC
Director Stock Option (right to buy)
M - Exercise -2.500 0 -100,00
2013-03-21 2013-03-20 4 ISIS ISIS PHARMACEUTICALS INC
Director Stock Option (right to buy)
M - Exercise -3.750 0 -100,00
2013-03-21 2013-03-20 4 ISIS ISIS PHARMACEUTICALS INC
Director Stock Option (right to buy)
M - Exercise -173 0 -100,00
2013-03-21 2013-03-20 4 ISIS ISIS PHARMACEUTICALS INC
Director Stock Option (right to buy)
M - Exercise -4.166 0 -100,00
2013-03-21 2013-03-20 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X -4.167 0 -100,00 18,00 -75.006
2013-03-21 2013-03-20 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X -4.167 0 -100,00 18,00 -75.006
2013-03-21 2013-03-20 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 4.167 4.167 9,77 40.712 40.712
2013-03-21 2013-03-20 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 4.167 4.167 9,77 40.712 40.712
2013-03-21 2013-03-20 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X -3.750 0 -100,00 18,00 -67.500
2013-03-21 2013-03-20 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 3.750 3.750 13,88 52.050 52.050
2013-03-21 2013-03-20 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X -174 0 -100,00 18,00 -3.132
2013-03-21 2013-03-20 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 174 174 5,93 1.032 1.032
2013-03-21 2013-03-20 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X -1.250 0 -100,00 18,00 -22.500
2013-03-21 2013-03-20 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X -1.250 0 -100,00 18,00 -22.500
2013-03-21 2013-03-20 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 1.250 1.250 9,22 11.525 11.525
2013-03-21 2013-03-20 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 1.250 1.250 9,22 11.525 11.525
2013-03-21 2013-03-20 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X -2.500 0 -100,00 18,00 -45.000
2013-03-21 2013-03-20 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 2.500 2.500 16,32 40.800 40.800
2013-03-21 2013-03-20 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X -3.750 0 -100,00 18,00 -67.500
2013-03-21 2013-03-20 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 3.750 3.750 13,88 52.050 52.050
2013-03-21 2013-03-20 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X -173 100 -63,37 18,00 -3.114 1.800
2013-03-21 2013-03-20 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 173 273 173,00 5,93 1.026 1.619
2013-03-21 2013-03-20 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X -2.500 100 -96,15 18,00 -45.000 1.800
2013-03-21 2013-03-20 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 2.500 2.600 2.500,00 16,32 40.800 42.432
2013-03-21 2013-03-20 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X -4.166 100 -97,66 18,00 -74.988 1.800
2013-03-21 2013-03-20 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 4.166 4.266 4.166,00 9,77 40.702 41.679
2013-03-21 2013-03-20 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X -3.750 100 -97,40 18,00 -67.500 1.800
2013-03-21 2013-03-20 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 3.750 3.850 3.750,00 13,88 52.050 53.438
2013-03-21 2013-03-19 4 ISIS ISIS PHARMACEUTICALS INC
Director Stock Option (right to buy)
M - Exercise -3.727 174 -95,54
2013-03-21 2013-03-19 4 ISIS ISIS PHARMACEUTICALS INC
Director Stock Option (right to buy)
M - Exercise -3.726 174 -95,54
2013-03-21 2013-03-19 4 ISIS ISIS PHARMACEUTICALS INC
Director Stock Option (right to buy)
M - Exercise -3.726 174 -95,54
2013-03-21 2013-03-19 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X -3.727 0 -100,00 18,00 -67.086
2013-03-21 2013-03-19 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 3.727 3.727 5,93 22.101 22.101
2013-03-21 2013-03-19 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X -3.726 0 -100,00 18,00 -67.068
2013-03-21 2013-03-19 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X -3.726 0 -100,00 18,00 -67.068
2013-03-21 2013-03-19 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 3.726 3.726 5,93 22.095 22.095
2013-03-21 2013-03-19 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 3.726 3.726 5,93 22.095 22.095
2013-03-14 2013-03-13 4 ISIS ISIS PHARMACEUTICALS INC
Director Stock Option (right to buy)
M - Exercise -6.667 0 -100,00
2013-03-14 2013-03-13 4 ISIS ISIS PHARMACEUTICALS INC
Director Stock Option (right to buy)
M - Exercise -6.667 0 -100,00
2013-03-14 2013-03-13 4 ISIS ISIS PHARMACEUTICALS INC
Director Stock Option (right to buy)
M - Exercise -266 3.901 -6,38
2013-03-14 2013-03-13 4 ISIS ISIS PHARMACEUTICALS INC
Director Stock Option (right to buy)
M - Exercise -266 3.901 -6,38
2013-03-14 2013-03-13 4 ISIS ISIS PHARMACEUTICALS INC
Director Stock Option (right to buy)
M - Exercise -6.666 0 -100,00
2013-03-14 2013-03-13 4 ISIS ISIS PHARMACEUTICALS INC
Director Stock Option (right to buy)
M - Exercise -268 3.899 -6,43
2013-03-14 2013-03-13 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X -6.667 0 -100,00 18,01 -120.052
2013-03-14 2013-03-13 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X -6.667 0 -100,00 18,01 -120.052
2013-03-14 2013-03-13 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 6.667 6.667 5,17 34.468 34.468
2013-03-14 2013-03-13 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 6.667 6.667 5,17 34.468 34.468
2013-03-14 2013-03-13 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X -266 0 -100,00 18,01 -4.790
2013-03-14 2013-03-13 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X -266 0 -100,00 18,01 -4.790
2013-03-14 2013-03-13 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 266 266 5,93 1.577 1.577
2013-03-14 2013-03-13 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 266 266 5,93 1.577 1.577
2013-03-14 2013-03-13 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X -6.666 100 -98,52 18,01 -120.034 1.801
2013-03-14 2013-03-13 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 6.666 6.766 6.666,00 5,17 34.463 34.980
2013-03-14 2013-03-13 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X -268 100 -72,83 18,01 -4.826 1.801
2013-03-14 2013-03-13 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 268 368 268,00 5,93 1.589 2.182
2012-07-03 2012-07-02 4 ISIS ISIS PHARMACEUTICALS INC
Director Stock Option (right to buy)
A - Award 11.250 11.250
2012-07-03 2012-07-02 4 ISIS ISIS PHARMACEUTICALS INC
Restricted Stock Units
A - Award 1.250 1.250
2012-01-05 2012-01-04 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
G - Gift 1.250 1.250
2012-01-05 2012-01-04 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
G - Gift 1.250 1.250
2012-01-05 2012-01-04 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
G - Gift 2.500 2.500
2012-01-05 2012-01-04 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
G - Gift 2.500 2.500
2012-01-05 2012-01-04 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
G - Gift 3.750 3.750
2012-01-05 2012-01-04 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
G - Gift 3.750 3.750
2012-01-05 2012-01-04 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
G - Gift 4.167 4.167
2012-01-05 2012-01-04 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
G - Gift 4.167 4.167
2012-01-05 2012-01-04 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
G - Gift 1.250 1.250
2012-01-05 2012-01-04 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
G - Gift 2.500 2.500
2012-01-05 2012-01-04 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
G - Gift 3.750 3.750
2012-01-05 2012-01-04 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
G - Gift 4.166 4.166
2012-01-05 2012-01-04 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
G - Gift -3.750 11.250 -25,00
2012-01-05 2012-01-04 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
G - Gift -7.500 7.500 -50,00
2012-01-05 2012-01-04 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
G - Gift -11.250 3.750 -75,00
2012-01-05 2012-01-04 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
G - Gift -12.500 0 -100,00
2012-01-03 2011-12-30 4 ISIS ISIS PHARMACEUTICALS INC
Director Stock Option (right to buy)
G - Gift 4.167 4.167
2012-01-03 2011-12-30 4 ISIS ISIS PHARMACEUTICALS INC
Director Stock Option (right to buy)
G - Gift 4.167 4.167
2012-01-03 2011-12-30 4 ISIS ISIS PHARMACEUTICALS INC
Director Stock Option (right to buy)
G - Gift 6.667 6.667
2012-01-03 2011-12-30 4 ISIS ISIS PHARMACEUTICALS INC
Director Stock Option (right to buy)
G - Gift 6.667 6.667
2012-01-03 2011-12-30 4 ISIS ISIS PHARMACEUTICALS INC
Director Stock Option (right to buy)
G - Gift 4.166 4.166
2012-01-03 2011-12-30 4 ISIS ISIS PHARMACEUTICALS INC
Director Stock Option (right to buy)
G - Gift 6.666 6.666
2012-01-03 2011-12-30 4 ISIS ISIS PHARMACEUTICALS INC
Director Stock Option (right to buy)
G - Gift -12.500 0 -100,00
2012-01-03 2011-12-30 4 ISIS ISIS PHARMACEUTICALS INC
Director Stock Option (right to buy)
G - Gift -20.000 0 -100,00
2009-06-08 2009-06-04 4 PDLI PDL BIOPHARMA, INC.
Common Stock
A - Award 6.983 16.983 69,83 7,16 49.998 121.598
2007-09-10 2007-09-06 4 PDLI PDL BIOPHARMA, INC.
Commn Stock
P - Purchase X 500 1.500 50,00 20,12 10.060 30.180
2005-12-15 3 ISIS ISIS PHARMACEUTICALS INC
Common Stock
100
P
Offener Markt oder privater Kauf von nicht-derivativen oder derivativen Wertpapieren
S
Freiverkauf oder privater Verkauf von nicht-derivativen oder derivativen Wertpapieren
A
Gewährung, Vergabe oder sonstiger Erwerb von Wertpapieren des Unternehmens (z. B. eine Option)
C
Umwandlung von Derivaten
D
Verkauf oder Rückübertragung von Wertpapieren an das Unternehmen
F
Zahlung des Ausübungspreises oder der Steuerschuld mit einem Teil der vom Unternehmen erhaltenen Wertpapiere
G
Schenkung von Wertpapieren durch oder an den Insider
K
Aktien-Swaps und ähnliche Absicherungstransaktionen
M
Ausübung oder Umwandlung eines vom Unternehmen erhaltenen derivativen Wertpapiers (z. B. einer Option)
V
Eine freiwillig auf Formular 4 gemeldete Transaktion
J
Sonstige (mit einer Fußnote zur Beschreibung der Transaktion)