| Ausstehende Aktien | 4,872,497 shares |
| Insider-Aktien | 736.084 shares |
| Insider-Besitz | 15,11 % |
| Insider gesamt | 41 |
Insider-Stimmungswert
Der Insider-Stimmungswert ermittelt die Unternehmen, die von Unternehmensinsidern gekauft werden.
Es ist das Ergebnis eines ausgeklügelten quantitativen Multifaktormodells, das die Unternehmen mit der höchsten Insiderakkumulation identifiziert. Das Scoring-Modell verwendet eine Kombination aus der Nettozahl der Insiderkäufe der letzten 90 Tage, der Gesamtzahl der gekauften Aktien als Prozentsatz des Streubesitzes und der Gesamtzahl der von Insidern gehaltenen Aktien. Die Zahl reicht von 0 bis 100, wobei höhere Zahlen ein höheres Maß an Insiderkäufen anzeigen als bei anderen Unternehmen und 50 den Durchschnitt darstellt.
Aktualisierungshäufigkeit: Täglich
Führungskräfte-Stimmungswert
Der Führungskräfte-Stimmungswert findet Unternehmen, die von Führungskräften des Unternehmens gekauft werden.
Per Definition sind Führungskräfte des Unternehmens Insider, aber im Gegensatz zu anderen Insidern (10%ige Aktionäre und Vorstandsmitglieder) arbeiten Führungskräfte täglich für das Unternehmen und verwenden beim Handel ihr eigenes Geld. (10%ige Aktionäre und Vorstandsmitglieder sind oft Fondsmanager, die das Geld anderer Leute verwalten.) Daher sind Insider-Geschäfte, die von Führungskräften getätigt werden, viel bedeutender und sollten entsprechend behandelt werden.
Wie der Insider-Stimmungswert ist auch der Führungskräfte-Stimmungswert das Ergebnis eines ausgeklügelten quantitativen Multifaktormodells, das die Unternehmen mit der höchsten Führungskräftekonzentration identifiziert.
Aktualisierungshäufigkeit: Täglich
Wichtige Insider-Kennzahlen
Diese Karte zeigt, wie das Unternehmen bei verschiedenen Insider-Kennzahlen abschneidet. Der Perzentil-Rang zeigt, wie dieses Unternehmen im Vergleich zu anderen Unternehmen auf den US-Märkten abschneidet. Höhere Ränge deuten auf eine bessere Situation hin.
Es ist beispielsweise allgemein anerkannt, dass Insiderkäufe ein positiver Indikator sind, so dass Unternehmen mit mehr Insiderkäufen besser abschneiden würden als Unternehmen mit weniger Insiderkäufen (oder sogar Insiderverkäufen).
Prozent des Streubesitzes von Insidern gekauft (Rang)
6734 out of 10791
Prozent des von Insidern gekauften Streubesitzes ist die Gesamtzahl der von Insidern gekauften Aktien abzüglich der Gesamtzahl der von Insidern in den letzten 90 Tagen verkauften Aktien, geteilt durch den gesamten Streubesitz und multipliziert mit 100.
Diagramm zum Insiderhandel
Calithera Biosciences, Inc. Insider-Trades sind in der folgenden Grafik dargestellt. Insider sind leitende Angestellte, Direktoren oder bedeutende Investoren in einem Unternehmen. Im Allgemeinen ist es für Insider illegal, auf der Grundlage von wesentlichen, nicht-öffentlichen Informationen mit Aktien ihrer Unternehmen zu handeln. Das bedeutet nicht, dass es für sie illegal ist, irgendwelche Geschäfte in ihren eigenen Unternehmen zu tätigen. Sie müssen jedoch alle Geschäfte der SEC über ein Formular 4 melden.
Kennzahlen zu Insiderlisten und Rentabilität
Diese Tabelle zeigt die Liste der bekannten Insider und wird automatisch aus den bei der SEC eingereichten Unterlagen erstellt. Zusätzlich zu den Namen, dem letzten Titel und der Bezeichnung als Direktor, leitender Angestellter oder 10%-iger Anteilseigner geben wir die zuletzt veröffentlichten Bestände an. Zusätzlich stellen wir, wenn möglich, die historische Handelsperformance für den Insider zur Verfügung. Die historische Handelsperformance ist ein gewichteter Durchschnitt der Performance tatsächlicher offener Kauftransaktionen, die von dem Insider getätigt wurden. Weitere Informationen zur Berechnung dieses Wertes finden Sie in diesem YouTube-Webinar.
See our leaderboard of most profitable insider traders.
| Insider | Durchschnittlicher Gewinn (%) | Aktien in Besitz |
Split Angepasst |
|---|---|---|---|
|
Adage Capital Partners Gp, L.l.c.
10% Owner -
|
3.546.873 | 177.344 | |
| Sunil Agarwal Director - [D] | 0 | 0 | |
|
ATV Associates VIII, L.L.C.
10% Owner -
|
2.110.082 | 105.504 | |
|
Adage Capital Advisors, L.L.C.
10% Owner -
|
3.546.873 | 177.344 | |
|
Adage Capital Partners, L.P.
10% Owner -
|
3.546.873 | 177.344 | |
|
Advanced Technology Ventures VIII LP
10% Owner -
|
2.110.082 | 105.504 | |
|
Robert Atchinson
10% Owner -
|
3.546.873 | 177.344 | |
| Biotechnology Value Fund Ii Lp - | 480.432 | 24.022 | |
| Biotechnology Value Fund L P - | 480.432 | 24.022 | |
|
James J Bochnowski
10% Owner -
|
23.464 | 1.173 | |
|
Bvf Inc/il
10% Owner -
|
480.432 | 24.022 | |
|
Bvf Partners L P/il
10% Owner -
|
480.432 | 24.022 | |
| BVF Partners OS Ltd. - | 480.432 | 24.022 |
| Insider | Durchschnittlicher Gewinn (%) | Aktien in Besitz |
Split Angepasst |
|---|---|---|---|
| Mark K Bennett SR. VP, RESEARCH - [O] | 10.413 | 521 | |
| Biotechnology Value Trading Fund OS LP - | 480.432 | 24.022 | |
|
Ralph E Christoffersen
Director, 10% Owner -
[D]
|
2.161.915 | 108.096 | |
|
Delphi Ventures Viii Lp
10% Owner -
|
23.464 | 1.173 | |
|
David L Douglass
10% Owner -
|
23.464 | 1.173 | |
| Jonathan G Drachman Director - [D] | 200.000 | 10.000 | |
|
Delphi BioInvestments VIII LP
10% Owner -
|
23.464 | 1.173 | |
|
Delphi Management Partners VIII, L.L.C.
10% Owner -
|
23.464 | 1.173 | |
| Garland J. Scott Director - [D] | 0 | 0 | |
|
Jean George
Director, 10% Owner -
[D]
|
2.110.082 | 105.504 | |
|
Phillip Gross
10% Owner -
|
3.546.873 | 177.344 | |
| Curtis Hecht CHIEF BUSINESS OFFICER - [O] | 92.321 | 4.616 | |
| Suzy Jones Director - [D] | 14.394 | 720 | |
| Emil Kuriakose CHIEF MEDICAL OFFICER - [O] | 3.539 | 3.539 |
| Insider | Durchschnittlicher Gewinn (%) | Aktien in Besitz |
Split Angepasst |
|---|---|---|---|
|
Mark N Lampert
10% Owner -
|
480.432 | 24.022 | |
|
Morgenthaler Venture Partners Ix Lp
10% Owner -
|
2.161.915 | 108.096 | |
| Christopher Molineaux SR. VP, DEVELOPMENT - [O] | 27.859 | 27.859 | |
| Susan Molineaux PRESIDENT & CEO, Director - [D] [O] | 27.859 | 27.859 | |
| Keith Orford Director - [O] | 66.094 | 3.305 | |
|
Deepika Pakianathan
Director, 10% Owner -
[D]
|
0 | 0 | |
| Francesco Parlati SR. VP, RESEARCH - [O] | 140.998 | 7.050 | |
|
Douglas A Roeder
10% Owner -
|
23.464 | 1.173 | |
| Sumita Ray See Remarks - [O] | 105.000 | 5.250 | |
| Eric Sjogren SR. VP, DRUG DISCOVERY - [O] | 8.467 | 8.467 | |
| Waddill William D. SR. VP & CFO - [O] | 17.485 | 874 | |
| Blake Wise Director - [D] | 0 | 0 | |
| Henry Ward Wolff Director - [D] | 0 | 0 | |
| Stephanie Wong See Remarks - [O] | 6.287 | 6.287 |
Report errors via our new Insider Auditing Tool
Erfolgsbilanz der Insiderkäufe - Kurzfristige Gewinnanalyse
In diesem Abschnitt analysieren wir die Rentabilität jedes ungeplanten Insiderkaufs, der auf dem freien Markt in CALA / Calithera Biosciences, Inc. getätigt wurde. Diese Analyse hilft zu verstehen, ob der Insider beständig abnormale Renditen erzielt und es sich lohnt, ihm zu folgen. Diese Analyse bezieht sich auf ein Jahr nach jedem Handel, und die Ergebnisse sind theoretisch .
Die folgende Tabelle zeigt die jüngsten Käufe am offenen Markt, die nicht Teil eines automatischen Handelsplans waren.
Bereinigter Preis ist der splitbereinigte Preis. Bereinigte Aktien sind die um den Split bereinigten Aktien.
Erfolgsbilanz von Insiderverkäufen - Kurzfristige Verlustanalyse
In diesem Abschnitt analysieren wir die kurzfristige Verlustvermeidung jedes ungeplanten Insider-Verkaufs auf dem freien Markt in CALA / Calithera Biosciences, Inc.. Ein konsistentes Muster der Verlustvermeidung kann darauf hindeuten, dass zukünftige Verkaufstransaktionen Kursrückgänge vorhersagen können. Diese Analyse bezieht sich auf ein Jahr nach jedem Handel, und die Ergebnisse sind theoretisch .
Die folgende Tabelle zeigt die jüngsten Verkäufe am offenen Markt, die nicht Teil eines automatischen Handelsplans waren.
Bereinigter Preis ist der splitbereinigte Preis. Bereinigte Aktien sind die um den Split bereinigten Aktien.
Transaktionshistorie
Klicken Sie auf das Link-Symbol, um den vollständigen Transaktionsverlauf anzuzeigen. Transaktionen, die im Rahmen eines automatischen Handelsplans 10b5-1 gemeldet werden, sind in der Spalte 10b-5 mit einem X gekennzeichnet.
| Datei Datum |
Handel Datum |
Form | Insider | Ticker | Wertpapier-Titel | Code | Direkt | Ausführung Preis |
Einheit Preis |
Eimheiten Verändert |
Wert Geändert (1K) |
Verbleibende Optionen |
Verbleibende Aktien |
|
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2023-01-31 | 2023-01-27 | 4 | PAKIANATHAN DEEPIKA Delphi BioInvestments VIII, L.P. | CALA | Common Stock | I | 0,3858 | -1.172 | -0 | 0 | ||||
| 2023-01-31 | 2023-01-27 | 4 | PAKIANATHAN DEEPIKA Delphi Ventures VIII, L.P. | CALA | Common Stock | I | 0,3858 | -120.161 | -46 | 0 | ||||
| 2023-01-25 | 2023-01-23 | 4 | Wong Stephanie | CALA | Common Stock | D | 0,4461 | -317 | -0 | 6.287 | ||||
| 2023-01-25 | 2023-01-23 | 4 | Molineaux Susan By Trust | CALA | Common Stock | I | 0,4461 | -526 | -0 | 27.859 | ||||
| 2023-01-25 | 2023-01-23 | 4 | Molineaux Christopher By Trust | CALA | Common Stock | I | 0,4461 | -217 | -0 | 27.859 | ||||
| 2023-01-25 | 2023-01-23 | 4 | Kuriakose Emil | CALA | Common Stock | D | 0,4461 | -79 | -0 | 3.539 | ||||
| 2023-01-25 | 2023-01-23 | 4 | Sjogren Eric | CALA | Common Stock | D | 0,4461 | -279 | -0 | 8.467 | ||||
| 2022-01-27 | 2022-01-25 | 4 | Molineaux Susan | CALA | Employee Stock Option (Right to Buy) | D | 0,44 | 597.475 | 597.475 | |||||
| 2022-01-27 | 2022-01-25 | 4 | Ray Sumita | CALA | Employee Stock Option (Right to Buy) | D | 0,44 | 165.000 | 165.000 | |||||
| 2022-01-27 | 2022-01-25 | 4 | Wong Stephanie | CALA | Employee Stock Option (Right to Buy) | D | 0,44 | 215.000 | 215.000 | |||||
| 2022-01-27 | 2022-01-25 | 4 | Molineaux Christopher | CALA | Employee Stock Option (Right to Buy) | D | 0,44 | 165.000 | 165.000 | |||||
| 2022-01-27 | 2022-01-25 | 4 | Parlati Francesco | CALA | Employee Stock Option (Right to Buy) | D | 0,44 | 165.000 | 165.000 | |||||
| 2022-01-27 | 2022-01-25 | 4 | Sjogren Eric | CALA | Employee Stock Option (Right to Buy) | D | 0,44 | 165.000 | 165.000 | |||||
| 2022-01-27 | 2022-01-25 | 4 | Orford Keith | CALA | Employee Stock Option (Right to Buy) | D | 0,44 | 40.000 | 40.000 | |||||
| 2022-01-27 | 2022-01-25 | 4 | Kuriakose Emil | CALA | Employee Stock Option (Right to Buy) | D | 0,44 | 215.000 | 215.000 | |||||
| 2022-01-25 | 2022-01-21 | 4 | Sjogren Eric | CALA | Common Stock | D | 0,4915 | -4.794 | -2 | 172.434 | ||||
| 2022-01-25 | 2022-01-21 | 4 | Kuriakose Emil | CALA | Common Stock | D | 0,4915 | -666 | -0 | 67.369 | ||||
| 2022-01-25 | 2022-01-21 | 4 | Wong Stephanie | CALA | Common Stock | D | 0,4915 | -5.586 | -3 | 132.085 | ||||
| 2022-01-25 | 2022-01-21 | 4 | Parlati Francesco | CALA | Common Stock | D | 0,4915 | -4.794 | -2 | 140.998 | ||||
| 2022-01-06 | 2022-01-04 | 4 | Parlati Francesco | CALA | Common Stock | D | 0,6604 | -18.077 | -12 | 145.792 | ||||
| 2022-01-06 | 2022-01-04 | 4 | Wong Stephanie | CALA | Common Stock | D | 0,6604 | -18.077 | -12 | 137.671 | ||||
| 2022-01-06 | 2022-01-04 | 4 | Sjogren Eric | CALA | Common Stock | D | 0,6604 | -18.077 | -12 | 177.228 | ||||
| 2022-01-06 | 2022-01-04 | 4 | Kuriakose Emil | CALA | Common Stock | D | 0,6604 | -3.855 | -3 | 68.035 | ||||
| 2021-11-12 | 2021-11-11 | 4 | Orford Keith | CALA | Common Stock | D | 0,8800 | -48.190 | -42 | 66.094 | ||||
| 2021-11-12 | 2021-11-10 | 4 | Orford Keith | CALA | Common Stock | D | 0,8565 | -30.000 | -26 | 114.284 | ||||
| 2021-11-10 | 2021-11-10 | 4 | Molineaux Susan By Trust | CALA | Common Stock | I | 0,8467 | 100.000 | 85 | 557.188 | ||||
| 2021-11-10 | 2021-11-10 | 4 | DRACHMAN JONATHAN G | CALA | Common Stock | D | 0,8595 | 200.000 | 172 | 200.000 | ||||
| 2021-11-10 | 2021-11-10 | 4 | Molineaux Christopher By Trust | CALA | Common Stock | I | 0,8467 | 100.000 | 85 | 557.188 | ||||
| 2021-11-09 | 2021-11-09 | 4 | Orford Keith | CALA | Common Stock | D | 0,8400 | -51.810 | -44 | 144.284 | ||||
| 2021-11-09 | 2021-11-05 | 4 | Orford Keith | CALA | Common Stock | D | 30.000 | 196.094 | ||||||
| 2021-11-09 | 2021-11-05 | 4 | Molineaux Christopher | CALA | Common Stock | D | 12.000 | 102.500 | ||||||
| 2021-11-09 | 2021-11-08 | 4 | Sjogren Eric | CALA | Common Stock | D | 0,8700 | -15.566 | -14 | 195.305 | ||||
| 2021-11-09 | 2021-11-05 | 4 | Sjogren Eric | CALA | Common Stock | D | 30.000 | 210.871 | ||||||
| 2021-11-09 | 2021-11-08 | 4 | Wong Stephanie | CALA | Common Stock | D | 0,8700 | -15.566 | -14 | 155.748 | ||||
| 2021-11-09 | 2021-11-05 | 4 | Wong Stephanie | CALA | Common Stock | D | 30.000 | 171.314 | ||||||
| 2021-11-09 | 2021-11-05 | 4 | Ray Sumita | CALA | Common Stock | D | 12.000 | 105.000 | ||||||
| 2021-11-09 | 2021-11-08 | 4 | Kuriakose Emil | CALA | Common Stock | D | 0,8700 | -3.077 | -3 | 69.390 | ||||
| 2021-11-09 | 2021-11-05 | 4 | Kuriakose Emil | CALA | Common Stock | D | 12.000 | 72.467 | ||||||
| 2021-11-09 | 2021-11-08 | 4 | Parlati Francesco | CALA | Common Stock | D | 0,8700 | -15.566 | -14 | 163.869 | ||||
| 2021-11-09 | 2021-11-05 | 4 | Parlati Francesco | CALA | Common Stock | D | 30.000 | 179.435 | ||||||
| 2021-11-09 | 3 | Kuriakose Emil | CALA | Common Stock | D | 60.467 | ||||||||
| 2021-10-29 | 2021-10-28 | 4 | Sjogren Eric | CALA | Common Stock | D | 1,8900 | -45.965 | -87 | 180.871 | ||||
| 2021-10-29 | 2021-10-27 | 4 | Sjogren Eric | CALA | Common Stock | D | 90.000 | 226.836 | ||||||
| 2021-10-29 | 2021-10-27 | 4 | Molineaux Christopher | CALA | Common Stock | D | 36.000 | 90.500 | ||||||
| 2021-10-29 | 2021-10-27 | 4 | Orford Keith | CALA | Common Stock | D | 90.000 | 166.094 | ||||||
| 2021-10-29 | 2021-10-28 | 4 | Wong Stephanie | CALA | Common Stock | D | 1,8900 | -45.965 | -87 | 141.314 | ||||
| 2021-10-29 | 2021-10-27 | 4 | Wong Stephanie | CALA | Common Stock | D | 90.000 | 187.279 | ||||||
| 2021-10-29 | 2021-10-28 | 4 | Parlati Francesco | CALA | Common Stock | D | 1,8900 | -45.965 | -87 | 149.435 | ||||
| 2021-10-29 | 2021-10-27 | 4 | Parlati Francesco | CALA | Common Stock | D | 90.000 | 195.400 | ||||||
| 2021-10-29 | 2021-10-27 | 4 | Ray Sumita | CALA | Common Stock | D | 36.000 | 93.000 | ||||||
| 2021-06-14 | 2021-06-11 | 4 | JONES SUZY | CALA | Stock Option (Right to Buy) | D | 2,28 | 20.000 | 20.000 | |||||
| 2021-06-14 | 2021-06-11 | 4 | AGARWAL SUNIL | CALA | Stock Option (Right to Buy) | D | 2,28 | 20.000 | 20.000 | |||||
| 2021-06-14 | 2021-06-11 | 4 | George Jean | CALA | Stock Option (Right to Buy) | D | 2,28 | 20.000 | 20.000 | |||||
| 2021-06-14 | 2021-06-11 | 4 | Garland J. Scott | CALA | Stock Option (Right to Buy) | D | 2,28 | 20.000 | 20.000 | |||||
| 2021-06-14 | 2021-06-11 | 4 | PAKIANATHAN DEEPIKA | CALA | Stock Option (Right to Buy) | D | 2,28 | 20.000 | 20.000 | |||||
| 2021-06-14 | 2021-06-11 | 4 | DRACHMAN JONATHAN G | CALA | Stock Option (Right to Buy) | D | 2,28 | 20.000 | 20.000 | |||||
| 2021-06-14 | 2021-06-11 | 4 | Wolff Henry Ward | CALA | Stock Option (Right to Buy) | D | 2,28 | 20.000 | 20.000 | |||||
| 2021-06-14 | 2021-06-11 | 4 | Wise Blake | CALA | Stock Option (Right to Buy) | D | 2,28 | 20.000 | 20.000 | |||||
| 2021-01-22 | 2021-01-20 | 4 | Hecht Curtis | CALA | Employee Stock Option (Right to Buy) | D | 2,98 | 150.000 | 150.000 | |||||
| 2021-01-22 | 2021-01-20 | 4 | Hecht Curtis | CALA | Common Stock | D | 30.000 | 92.321 | ||||||
| 2021-01-22 | 2021-01-20 | 4 | Hecht Curtis | CALA | Common Stock | D | 35.000 | 62.321 | ||||||
| 2021-01-22 | 2021-01-20 | 4 | Molineaux Christopher | CALA | Employee Stock Option (Right to Buy) | D | 2,98 | 125.000 | 125.000 | |||||
| 2021-01-22 | 2021-01-20 | 4 | Molineaux Christopher | CALA | Common Stock | D | 12.000 | 52.000 | ||||||
| 2021-01-22 | 2021-01-20 | 4 | Molineaux Christopher | CALA | Common Stock | D | 30.000 | 40.000 | ||||||
| 2021-01-22 | 2021-01-20 | 4 | Molineaux Susan | CALA | Employee Stock Option (Right to Buy) | D | 2,98 | 375.000 | 375.000 | |||||
| 2021-01-22 | 2021-01-20 | 4 | Molineaux Susan | CALA | Common Stock | D | 85.000 | 95.000 | ||||||
| 2021-01-22 | 2021-01-20 | 4 | Ray Sumita | CALA | Employee Stock Option (Right to Buy) | D | 2,98 | 125.000 | 125.000 | |||||
| 2021-01-22 | 2021-01-20 | 4 | Ray Sumita | CALA | Common Stock | D | 12.000 | 57.000 | ||||||
| 2021-01-22 | 2021-01-20 | 4 | Ray Sumita | CALA | Common Stock | D | 30.000 | 45.000 | ||||||
| 2021-01-22 | 2021-01-20 | 4 | Orford Keith | CALA | Employee Stock Option (Right to Buy) | D | 2,98 | 150.000 | 150.000 | |||||
| 2021-01-22 | 2021-01-20 | 4 | Orford Keith | CALA | Common Stock | D | 30.000 | 76.094 | ||||||
| 2021-01-22 | 2021-01-20 | 4 | Orford Keith | CALA | Common Stock | D | 35.000 | 46.094 | ||||||
| 2021-01-22 | 2021-01-20 | 4 | Parlati Francesco | CALA | Employee Stock Option (Right to Buy) | D | 2,98 | 125.000 | 125.000 | |||||
| 2021-01-22 | 2021-01-20 | 4 | Parlati Francesco | CALA | Common Stock | D | 30.000 | 105.400 | ||||||
| 2021-01-22 | 2021-01-20 | 4 | Parlati Francesco | CALA | Common Stock | D | 30.000 | 105.400 | ||||||
| 2021-01-22 | 2021-01-20 | 4 | Sjogren Eric | CALA | Employee Stock Option (Right to Buy) | D | 2,98 | 125.000 | 125.000 | |||||
| 2021-01-22 | 2021-01-20 | 4 | Sjogren Eric | CALA | Common Stock | D | 30.000 | 134.336 | ||||||
| 2021-01-22 | 2021-01-20 | 4 | Sjogren Eric | CALA | Common Stock | D | 30.000 | 134.336 | ||||||
| 2021-01-22 | 2021-01-20 | 4 | Wong Stephanie | CALA | Employee Stock Option (Right to Buy) | D | 2,98 | 150.000 | 150.000 | |||||
| 2021-01-22 | 2021-01-20 | 4 | Wong Stephanie | CALA | Common Stock | D | 30.000 | 103.156 | ||||||
| 2021-01-22 | 2021-01-20 | 4 | Wong Stephanie | CALA | Common Stock | D | 35.000 | 73.156 | ||||||
| 2020-12-18 | 2020-12-16 | 4 | Orford Keith | CALA | Common Stock | D | 6,0000 | -2.447 | -15 | 11.094 | ||||
| 2020-08-04 | 2020-07-31 | 4 | Garland J. Scott | CALA | Stock Option (Right to Buy) | D | 4,70 | 40.000 | 40.000 | |||||
| 2020-07-14 | 3 | Garland J. Scott | CALA | No securities beneficially owned | D | 0 | ||||||||
| 2020-06-11 | 2020-06-09 | 4 | AGARWAL SUNIL | CALA | Stock Option (Right to Buy) | D | 5,25 | 20.000 | 20.000 | |||||
| 2020-06-11 | 2020-06-09 | 4 | PAKIANATHAN DEEPIKA | CALA | Stock Option (Right to Buy) | D | 5,25 | 20.000 | 20.000 | |||||
| 2020-06-11 | 2020-06-09 | 4 | DRACHMAN JONATHAN G | CALA | Stock Option (Right to Buy) | D | 5,25 | 20.000 | 20.000 | |||||
| 2020-06-11 | 2020-06-09 | 4 | JONES SUZY | CALA | Stock Option (Right to Buy) | D | 5,25 | 20.000 | 20.000 | |||||
| 2020-06-11 | 2020-06-09 | 4 | George Jean | CALA | Stock Option (Right to Buy) | D | 5,25 | 20.000 | 20.000 | |||||
| 2020-06-11 | 2020-06-09 | 4 | Wise Blake | CALA | Stock Option (Right to Buy) | D | 5,25 | 20.000 | 20.000 | |||||
| 2020-06-11 | 2020-06-09 | 4 | Wolff Henry Ward | CALA | Stock Option (Right to Buy) | D | 5,25 | 20.000 | 20.000 | |||||
| 2020-05-26 | 2020-05-21 | 4 | BVF PARTNERS L P/IL | CALA | Common Stock, $0.0001 par value | D | 6,0000 | -192.250 | -1.154 | 480.432 | ||||
| 2020-05-26 | 2020-05-21 | 4 | BVF PARTNERS L P/IL | CALA | Common Stock, $0.0001 par value | D | 6,0000 | -1.064.332 | -6.386 | 2.766.561 | ||||
| 2020-05-26 | 2020-05-21 | 4 | BVF PARTNERS L P/IL | CALA | Common Stock, $0.0001 par value | D | 6,0000 | -1.027.016 | -6.162 | 3.712.340 | ||||
| 2020-04-17 | 2020-04-15 | 4 | Wong Stephanie | CALA | Common Stock | D | 8,0000 | -5.000 | -40 | 30.082 | ||||
| 2020-02-24 | 2020-02-20 | 4 | Orford Keith | CALA | Common Stock | D | 8,0000 | -3.021 | -24 | 8.541 | ||||
| 2020-01-22 | 2020-01-18 | 4 | Molineaux Susan | CALA | Employee Stock Option (Right to Buy) | D | 7,41 | 400.000 | 400.000 | |||||
| 2020-01-22 | 2020-01-17 | 4 | Molineaux Christopher | CALA | Employee Stock Option (Right to Buy) | D | 7,41 | 110.000 | 110.000 | |||||
| 2020-01-22 | 2020-01-17 | 4 | Hecht Curtis | CALA | Employee Stock Option (Right to Buy) | D | 7,41 | 120.000 | 120.000 | |||||
| 2020-01-22 | 2020-01-17 | 4 | Ray Sumita | CALA | Stock Option (Right to Buy) | D | 7,41 | 110.000 | 110.000 | |||||
| 2020-01-22 | 2020-01-17 | 4 | Wong Stephanie | CALA | Employee Stock Option (Right to Buy) | D | 7,41 | 120.000 | 120.000 | |||||
| 2020-01-22 | 2020-01-17 | 4 | Sjogren Eric | CALA | Employee Stock Option (Right to Buy) | D | 7,41 | 110.000 | 110.000 | |||||
| 2020-01-22 | 2020-01-17 | 4 | Parlati Francesco | CALA | Employee Stock Option (Right to Buy) | D | 7,41 | 75.000 | 75.000 | |||||
| 2020-01-22 | 2020-01-17 | 4 | Orford Keith | CALA | Stock Option (Right to Buy) | D | 7,41 | 140.000 | 140.000 | |||||
| 2019-12-26 | 2019-12-23 | 4 | Orford Keith | CALA | Common Stock | D | 6,0000 | -3.021 | -18 | 11.562 | ||||
| 2019-11-22 | 2019-11-20 | 4 | BVF PARTNERS L P/IL | CALA | Common Stock, $0.0001 par value | D | 3,9116 | 14.151 | 55 | 672.682 | ||||
| 2019-11-22 | 2019-11-20 | 4 | BVF PARTNERS L P/IL | CALA | Common Stock, $0.0001 par value | D | 3,9116 | 79.285 | 310 | 3.830.893 | ||||
| 2019-11-22 | 2019-11-20 | 4 | BVF PARTNERS L P/IL | CALA | Common Stock, $0.0001 par value | D | 3,9116 | 98.518 | 385 | 4.739.356 | ||||
| 2019-11-18 | 2019-11-14 | 4 | BVF PARTNERS L P/IL | CALA | Common Stock, $0.0001 par value | D | 3,3700 | 11.105 | 37 | 658.531 | ||||
| 2019-11-18 | 2019-11-14 | 4 | BVF PARTNERS L P/IL | CALA | Common Stock, $0.0001 par value | D | 3,3700 | 45.888 | 155 | 3.751.608 | ||||
| 2019-11-18 | 2019-11-14 | 4 | BVF PARTNERS L P/IL | CALA | Common Stock, $0.0001 par value | D | 3,3700 | 71.495 | 241 | 4.640.838 | ||||
| 2019-10-31 | 2019-10-30 | 4 | BVF PARTNERS L P/IL | CALA | Common Stock, $0.0001 par value | D | 2,7000 | 57.868 | 156 | 647.426 | ||||
| 2019-10-31 | 2019-10-30 | 4 | BVF PARTNERS L P/IL | CALA | Common Stock, $0.0001 par value | D | 2,7000 | 331.048 | 894 | 3.705.720 | ||||
| 2019-10-31 | 2019-10-30 | 4 | BVF PARTNERS L P/IL | CALA | Common Stock, $0.0001 par value | D | 2,7000 | 408.592 | 1.103 | 4.569.343 | ||||
| 2019-10-31 | 2019-10-29 | 4 | BVF PARTNERS L P/IL | CALA | Common Stock, $0.0001 par value | D | 2,6000 | 116.552 | 303 | 589.558 | ||||
| 2019-10-31 | 2019-10-29 | 4 | BVF PARTNERS L P/IL | CALA | Common Stock, $0.0001 par value | D | 2,6000 | 610.052 | 1.586 | 3.374.672 | ||||
| 2019-10-31 | 2019-10-29 | 4 | BVF PARTNERS L P/IL | CALA | Common Stock, $0.0001 par value | D | 2,6000 | 872.373 | 2.268 | 4.160.751 | ||||
| 2019-07-01 | 3 | LAMPERT MARK N | CALA | Common Stock, $0.0001 par value | D | 9.814.382 | ||||||||
| 2019-07-01 | 3 | LAMPERT MARK N | CALA | Common Stock, $0.0001 par value | D | 9.814.382 | ||||||||
| 2019-07-01 | 3 | LAMPERT MARK N | CALA | Common Stock, $0.0001 par value | D | 9.290.624 | ||||||||
| 2019-07-01 | 3 | LAMPERT MARK N | CALA | Common Stock, $0.0001 par value | D | 6.999.010 | ||||||||
| 2019-07-01 | 3 | LAMPERT MARK N | CALA | Common Stock, $0.0001 par value | D | 9.814.382 | ||||||||
| 2019-07-01 | 3 | LAMPERT MARK N | CALA | Common Stock, $0.0001 par value | D | 9.290.624 | ||||||||
| 2019-07-01 | 3 | LAMPERT MARK N | CALA | Common Stock, $0.0001 par value | D | 6.999.010 | ||||||||
| 2019-07-01 | 3 | LAMPERT MARK N | CALA | Common Stock, $0.0001 par value | D | 9.814.382 | ||||||||
| 2019-07-01 | 3 | LAMPERT MARK N | CALA | Common Stock, $0.0001 par value | D | 9.290.624 | ||||||||
| 2019-07-01 | 3 | LAMPERT MARK N | CALA | Common Stock, $0.0001 par value | D | 6.999.010 | ||||||||
| 2019-07-01 | 3 | LAMPERT MARK N | CALA | Common Stock, $0.0001 par value | D | 9.814.382 | ||||||||
| 2019-07-01 | 3 | LAMPERT MARK N | CALA | Common Stock, $0.0001 par value | D | 9.290.624 | ||||||||
| 2019-07-01 | 3 | LAMPERT MARK N | CALA | Common Stock, $0.0001 par value | D | 6.999.010 | ||||||||
| 2019-07-01 | 3 | LAMPERT MARK N | CALA | Common Stock, $0.0001 par value | D | 9.814.382 | ||||||||
| 2019-07-01 | 3 | LAMPERT MARK N | CALA | Common Stock, $0.0001 par value | D | 9.290.624 | ||||||||
| 2019-07-01 | 3 | LAMPERT MARK N | CALA | Common Stock, $0.0001 par value | D | 6.999.010 | ||||||||
| 2019-07-01 | 3 | LAMPERT MARK N | CALA | Common Stock, $0.0001 par value | D | 9.814.382 | ||||||||
| 2019-07-01 | 3 | LAMPERT MARK N | CALA | Common Stock, $0.0001 par value | D | 9.290.624 | ||||||||
| 2019-07-01 | 3 | LAMPERT MARK N | CALA | Common Stock, $0.0001 par value | D | 6.999.010 | ||||||||
| 2019-07-01 | 3 | LAMPERT MARK N | CALA | Common Stock, $0.0001 par value | D | 9.290.624 | ||||||||
| 2019-07-01 | 3 | LAMPERT MARK N | CALA | Common Stock, $0.0001 par value | D | 6.999.010 | ||||||||
| 2019-07-01 | 3 | LAMPERT MARK N | CALA | Common Stock, $0.0001 par value | D | 9.814.382 | ||||||||
| 2019-07-01 | 3 | LAMPERT MARK N | CALA | Common Stock, $0.0001 par value | D | 9.290.624 | ||||||||
| 2019-07-01 | 3 | LAMPERT MARK N | CALA | Common Stock, $0.0001 par value | D | 6.999.010 | ||||||||
| 2019-07-01 | 3 | LAMPERT MARK N | CALA | Common Stock, $0.0001 par value | D | 9.814.382 | ||||||||
| 2019-07-01 | 3 | LAMPERT MARK N | CALA | Common Stock, $0.0001 par value | D | 9.290.624 | ||||||||
| 2019-07-01 | 3 | LAMPERT MARK N | CALA | Common Stock, $0.0001 par value | D | 6.999.010 | ||||||||
| 2019-06-27 | 2019-06-25 | 4 | Molineaux Susan By Trust | CALA | Common Stock | I | 3,8800 | 51.600 | 200 | 457.188 | ||||
| 2019-06-27 | 2019-06-25 | 4 | Molineaux Christopher By Trust | CALA | Common Stock | I | 3,8800 | 51.600 | 200 | 457.188 | ||||
| 2019-06-26 | 2019-06-24 | 4 | Sjogren Eric | CALA | Employee Stock Option (Right to Buy) | D | 0,96 | -21.739 | 0 | |||||
| 2019-06-26 | 2019-06-24 | 4 | Sjogren Eric | CALA | Common Stock | D | 0,9600 | 21.739 | 21 | 72.057 | ||||
| 2019-06-21 | 2019-06-19 | 4 | Wong Stephanie | CALA | Employee Stock Option (Right to Buy) | D | 2,64 | -10.000 | 13.284 | |||||
| 2019-06-21 | 2019-06-19 | 4 | Wong Stephanie | CALA | Common Stock | D | 2,6400 | 10.000 | 26 | 31.751 | ||||
| 2019-06-19 | 2019-06-17 | 4 | Orford Keith | CALA | Common Stock | D | 6,0000 | -417 | -3 | 12.083 | ||||
| 2019-06-19 | 2019-06-17 | 4 | Parlati Francesco | CALA | Employee Stock Option (Right to Buy) | D | 2,64 | -6.246 | 0 | |||||
| 2019-06-19 | 2019-06-17 | 4 | Parlati Francesco | CALA | Common Stock | D | 2,6400 | 6.246 | 16 | 42.201 | ||||
| 2019-06-03 | 2019-05-30 | 4 | George Jean | CALA | Stock Option (Right to Buy) | D | 5,42 | 11.000 | 11.000 | |||||
| 2019-06-03 | 2019-05-30 | 4 | AGARWAL SUNIL | CALA | Stock Option (Right to Buy) | D | 5,42 | 11.000 | 11.000 | |||||
| 2019-06-03 | 2019-05-30 | 4 | JONES SUZY | CALA | Stock Option (Right to Buy) | D | 5,42 | 11.000 | 11.000 | |||||
| 2019-06-03 | 2019-05-30 | 4 | DRACHMAN JONATHAN G | CALA | Stock Option (Right to Buy) | D | 5,42 | 11.000 | 11.000 | |||||
| 2019-06-03 | 2019-05-30 | 4 | PAKIANATHAN DEEPIKA | CALA | Stock Option (Right to Buy) | D | 5,42 | 11.000 | 11.000 | |||||
| 2019-06-03 | 2019-05-30 | 4 | Wolff Henry Ward | CALA | Stock Option (Right to Buy) | D | 5,42 | 11.000 | 11.000 | |||||
| 2019-06-03 | 2019-05-30 | 4 | Wise Blake | CALA | Stock Option (Right to Buy) | D | 5,42 | 11.000 | 11.000 | |||||
| 2019-05-24 | 2019-05-22 | 4 | Orford Keith | CALA | Common Stock | D | 6,0000 | -416 | -2 | 10.000 | ||||
| 2019-04-17 | 2019-04-15 | 4 | Orford Keith | CALA | Common Stock | D | 6,3300 | -416 | -3 | 10.416 | ||||
| 2019-03-19 | 2019-03-15 | 4 | Orford Keith | CALA | Common Stock | D | 6,4300 | -417 | -3 | 10.832 | ||||
| 2019-03-13 | 2019-03-11 | 4 | Orford Keith | CALA | Common Stock | D | 6,0000 | -1.565 | -9 | 11.249 | ||||
| 2019-02-11 | 2019-02-07 | 4 | Molineaux Susan By Trust | CALA | Common Stock | I | -12.986 | 395.588 | ||||||
| 2019-02-11 | 2019-02-07 | 4 | Molineaux Christopher By Trust | CALA | Common Stock | I | -12.986 | 395.588 | ||||||
| 2019-01-14 | 2019-01-10 | 4 | Ray Sumita | CALA | Stock Option (Right to Buy) | D | 4,64 | 90.000 | 90.000 | |||||
| 2019-01-14 | 2019-01-10 | 4 | Wong Stephanie | CALA | Employee Stock Option (Right to Buy) | D | 4,64 | 120.000 | 120.000 | |||||
| 2019-01-14 | 2019-01-10 | 4 | Hecht Curtis | CALA | Employee Stock Option (Right to Buy) | D | 4,64 | 117.000 | 117.000 | |||||
| 2019-01-14 | 2019-01-10 | 4 | Orford Keith | CALA | Stock Option (Right to Buy) | D | 4,64 | 132.000 | 132.000 | |||||
| 2019-01-14 | 2019-01-10 | 4 | Molineaux Susan | CALA | Employee Stock Option (Right to Buy) | D | 4,64 | 390.000 | 390.000 | |||||
| 2019-01-14 | 2019-01-10 | 4 | Parlati Francesco | CALA | Employee Stock Option (Right to Buy) | D | 4,64 | 47.000 | 47.000 | |||||
| 2019-01-14 | 2019-01-10 | 4 | Sjogren Eric | CALA | Employee Stock Option (Right to Buy) | D | 4,64 | 100.000 | 100.000 | |||||
| 2019-01-14 | 2019-01-10 | 4 | Molineaux Christopher | CALA | Employee Stock Option (Right to Buy) | D | 4,64 | 105.000 | 105.000 | |||||
| 2018-11-16 | 2018-11-14 | 4 | Molineaux Christopher By Trust | CALA | Common Stock | I | -6.476 | 408.574 | ||||||
| 2018-11-16 | 2018-11-14 | 4 | Molineaux Susan By Trust | CALA | Common Stock | I | -6.476 | 408.574 | ||||||
| 2018-10-17 | 2018-10-15 | 4 | Orford Keith | CALA | Common Stock | D | 6,0500 | -313 | -2 | 10.314 | ||||
| 2018-10-15 | 2018-10-11 | 4 | Orford Keith | CALA | Common Stock | D | 6,0000 | -1.252 | -8 | 10.627 | ||||
| 2018-10-11 | 2018-10-09 | 4 | Ray Sumita | CALA | Stock Option (Right to Buy) | D | 5,61 | 25.000 | 25.000 | |||||
| 2018-06-04 | 2018-05-31 | 4 | JONES SUZY | CALA | Stock Option (Right to Buy) | D | 5,15 | 11.000 | 11.000 | |||||
| 2018-06-04 | 2018-05-31 | 4 | AGARWAL SUNIL | CALA | Stock Option (Right to Buy) | D | 5,15 | 11.000 | 11.000 | |||||
| 2018-06-04 | 2018-05-31 | 4 | Wise Blake | CALA | Stock Option (Right to Buy) | D | 5,15 | 11.000 | 11.000 | |||||
| 2018-06-04 | 2018-05-31 | 4 | Wolff Henry Ward | CALA | Stock Option (Right to Buy) | D | 5,15 | 11.000 | 11.000 | |||||
| 2018-06-04 | 2018-05-31 | 4 | DRACHMAN JONATHAN G | CALA | Stock Option (Right to Buy) | D | 5,15 | 11.000 | 11.000 | |||||
| 2018-06-04 | 2018-05-31 | 4 | George Jean | CALA | Stock Option (Right to Buy) | D | 5,15 | 11.000 | 11.000 | |||||
| 2018-06-04 | 2018-05-31 | 4 | PAKIANATHAN DEEPIKA | CALA | Stock Option (Right to Buy) | D | 5,15 | 11.000 | 11.000 | |||||
| 2018-04-05 | 2018-04-03 | 4 | Sjogren Eric | CALA | Employee Stock Option (Right to Buy) | D | 0,48 | -8.601 | 0 | |||||
| 2018-04-05 | 2018-04-03 | 4 | Sjogren Eric | CALA | Employee Stock Option (Right to Buy) | D | 0,48 | -8.209 | 0 | |||||
| 2018-04-05 | 2018-04-03 | 4 | Sjogren Eric | CALA | Common Stock | D | 0,4800 | 16.810 | 8 | 42.818 | ||||
| 2018-03-06 | 3/A | Parlati Francesco | CALA | Common Stock | D | 20.349 | ||||||||
| 2018-03-06 | 2018-02-20 | 4/A | Parlati Francesco | CALA | Employee Stock Option (Right to Buy) | D | 0,96 | -3.116 | 0 | |||||
| 2018-03-06 | 2018-02-20 | 4/A | Parlati Francesco | CALA | Employee Stock Option (Right to Buy) | D | 0,96 | -1.979 | 0 | |||||
| 2018-03-06 | 2018-02-20 | 4/A | Parlati Francesco | CALA | Common Stock | D | 0,9600 | 3.116 | 3 | 28.455 | ||||
| 2018-03-06 | 2018-02-20 | 4/A | Parlati Francesco | CALA | Common Stock | D | 0,9600 | 1.979 | 2 | 25.339 | ||||
| 2018-03-06 | 2018-03-02 | 4 | Molineaux Christopher By Spouse | CALA | Employee Stock Option (Right to Buy) | I | 2,64 | -26.992 | 9.729 | |||||
| 2018-03-06 | 2018-03-02 | 4 | Molineaux Christopher | CALA | Employee Stock Option (Right to Buy) | D | 2,64 | -6.798 | 0 | |||||
| 2018-03-06 | 2018-03-02 | 4 | Molineaux Christopher | CALA | Common Stock | D | 2,6400 | 6.798 | 18 | 21.000 | ||||
| 2018-03-06 | 2018-03-02 | 4 | Molineaux Susan By Spouse | CALA | Employee Stock Option (Right to Buy) | I | 2,64 | -6.798 | 0 | |||||
| 2018-03-06 | 2018-03-02 | 4 | Molineaux Susan | CALA | Employee Stock Option (Right to Buy) | D | 2,64 | -26.992 | 9.729 | |||||
| 2018-03-06 | 2018-03-02 | 4 | Molineaux Susan | CALA | Common Stock | D | 2,6400 | 26.992 | 71 | 44.860 | ||||
| 2018-02-27 | 2018-02-23 | 4 | Wong Stephanie | CALA | Employee Stock Option (Right to Buy) | D | 2,64 | -10.000 | 21.596 | |||||
| 2018-02-27 | 2018-02-23 | 4 | Wong Stephanie | CALA | Common Stock | D | 2,6400 | 10.000 | 26 | 15.000 | ||||
| 2018-02-22 | 2018-02-20 | 4 | Parlati Francesco | CALA | Employee Stock Option (Right to Buy) | D | 0,96 | -3.116 | 0 | |||||
| 2018-02-22 | 2018-02-20 | 4 | Parlati Francesco | CALA | Employee Stock Option (Right to Buy) | D | 0,96 | -1.979 | 0 | |||||
| 2018-02-22 | 2018-02-20 | 4 | Parlati Francesco | CALA | Common Stock | D | 0,9600 | 3.116 | 3 | 20.488 | ||||
| 2018-02-22 | 2018-02-20 | 4 | Parlati Francesco | CALA | Common Stock | D | 0,9600 | 1.979 | 2 | 17.372 | ||||
| 2018-01-16 | 2018-01-11 | 4 | Sjogren Eric | CALA | Employee Stock Option (Right to Buy) | D | 8,60 | 60.000 | 60.000 | |||||
| 2018-01-16 | 2018-01-11 | 4 | Orford Keith | CALA | Stock Option (Right to Buy) | D | 8,60 | 70.000 | 70.000 | |||||
| 2018-01-16 | 2018-01-11 | 4 | Molineaux Christopher | CALA | Employee Stock Option (Right to Buy) | D | 8,60 | 65.000 | 65.000 | |||||
| 2018-01-16 | 2018-01-11 | 4 | Molineaux Susan | CALA | Employee Stock Option (Right to Buy) | D | 8,60 | 200.000 | 200.000 | |||||
| 2018-01-16 | 2018-01-11 | 4 | Hecht Curtis | CALA | Employee Stock Option (Right to Buy) | D | 8,60 | 70.000 | 70.000 | |||||
| 2018-01-16 | 2018-01-11 | 4 | Parlati Francesco | CALA | Employee Stock Option (Right to Buy) | D | 8,60 | 30.000 | 30.000 | |||||
| 2018-01-16 | 2018-01-11 | 4 | Wong Stephanie | CALA | Employee Stock Option (Right to Buy) | D | 8,60 | 70.000 | 70.000 | |||||
| 2017-12-06 | 2017-12-05 | 4 | Molineaux Christopher By Spouse | CALA | Employee Stock Option (Right to Buy) | I | 2,64 | -5.300 | 34.030 | |||||
| 2017-12-06 | 2017-12-05 | 4 | Molineaux Christopher By Spouse | CALA | Employee Stock Option (Right to Buy) | I | 0,96 | -7.568 | 0 | |||||
| 2017-12-06 | 2017-12-05 | 4 | Molineaux Christopher | CALA | Employee Stock Option (Right to Buy) | D | 2,64 | -2.700 | 6.006 | |||||
| 2017-12-06 | 2017-12-05 | 4 | Molineaux Christopher | CALA | Employee Stock Option (Right to Buy) | D | 0,96 | -6.502 | 0 | |||||
| 2017-12-06 | 2017-12-05 | 4 | Molineaux Christopher | CALA | Common Stock | D | 2,6400 | 2.700 | 7 | 11.702 | ||||
| 2017-12-06 | 2017-12-05 | 4 | Molineaux Christopher | CALA | Common Stock | D | 0,9600 | 6.502 | 6 | 9.002 | ||||
| 2017-12-06 | 2017-12-05 | 4 | Molineaux Susan By Spouse | CALA | Employee Stock Option (Right to Buy) | I | 2,64 | -2.700 | 6.006 | |||||
| 2017-12-06 | 2017-12-05 | 4 | Molineaux Susan By Spouse | CALA | Employee Stock Option (Right to Buy) | I | 0,96 | -6.502 | 0 | |||||
| 2017-12-06 | 2017-12-05 | 4 | Molineaux Susan | CALA | Employee Stock Option (Right to Buy) | D | 2,64 | -5.300 | 34.030 | |||||
| 2017-12-06 | 2017-12-05 | 4 | Molineaux Susan | CALA | Employee Stock Option (Right to Buy) | D | 0,96 | -7.568 | 0 | |||||
| 2017-12-06 | 2017-12-05 | 4 | Molineaux Susan | CALA | Common Stock | D | 2,6400 | 5.300 | 14 | 15.368 | ||||
| 2017-12-06 | 2017-12-05 | 4 | Molineaux Susan | CALA | Common Stock | D | 0,9600 | 7.568 | 7 | 10.068 | ||||
| 2017-10-03 | 3 | Ray Sumita | CALA | No securities beneficially owned | D | 0 | ||||||||
| 2017-10-03 | 2017-09-29 | 4 | Ray Sumita | CALA | Stock Option (Right to Buy) | D | 15,75 | 75.000 | 75.000 | |||||
| 2017-10-03 | 2017-09-20 | 4 | Wise Blake | CALA | Stock Option (Right to Buy) | D | 15,75 | 22.000 | 22.000 | |||||
| 2017-09-28 | 2017-09-28 | 4 | ADAGE CAPITAL PARTNERS GP, L.L.C. | CALA | Common Stock | I | 15,5000 | -38.000 | -589 | 3.546.873 | ||||
| 2017-09-28 | 2017-09-27 | 4 | ADAGE CAPITAL PARTNERS GP, L.L.C. | CALA | Common Stock | I | 15,5900 | -186.000 | -2.900 | 3.584.873 | ||||
| 2017-09-28 | 2017-09-26 | 4 | ADAGE CAPITAL PARTNERS GP, L.L.C. | CALA | Common Stock, par value $0.0001 ("Common Stock") | I | 15,6800 | -352.000 | -5.519 | 3.770.873 | ||||
| 2017-09-21 | 3 | Wise Blake | CALA | No securities beneficially owned | D | 0 | ||||||||
| 2017-07-19 | 2017-07-17 | 4 | Wong Stephanie By Trust | CALA | Common Stock | I | 18,4078 | -3.552 | -65 | 10.550 | ||||
| 2017-07-19 | 2017-07-17 | 4 | Orford Keith | CALA | Common Stock | D | 18,3126 | -2.120 | -39 | 6.879 | ||||
| 2017-07-07 | 2017-07-06 | 4 | Hecht Curtis | CALA | Common Stock | D | 18,0000 | -700 | -13 | 15.940 | ||||
| 2017-06-13 | 2017-06-09 | 4 | PAKIANATHAN DEEPIKA | CALA | Stock Option (Right to Buy) | D | 14,20 | 11.000 | 11.000 | |||||
| 2017-06-13 | 2017-06-09 | 4 | AGARWAL SUNIL | CALA | Stock Option (Right to Buy) | D | 14,20 | 11.000 | 11.000 | |||||
| 2017-06-13 | 2017-06-09 | 4 | JONES SUZY | CALA | Stock Option (Right to Buy) | D | 14,20 | 11.000 | 11.000 | |||||
| 2017-06-13 | 2017-06-09 | 4 | George Jean | CALA | Stock Option (Right to Buy) | D | 14,20 | 11.000 | 11.000 | |||||
| 2017-06-13 | 2017-06-09 | 4 | Wolff Henry Ward | CALA | Stock Option (Right to Buy) | D | 14,20 | 11.000 | 11.000 | |||||
| 2017-06-13 | 2017-06-09 | 4 | DRACHMAN JONATHAN G | CALA | Stock Option (Right to Buy) | D | 14,20 | 11.000 | 11.000 | |||||
| 2017-05-23 | 2017-05-19 | 4 | Hecht Curtis | CALA | Common Stock | D | 16,0000 | -650 | -10 | 14.910 | ||||
| 2017-03-24 | 2017-03-22 | 4 | ADAGE CAPITAL PARTNERS GP, L.L.C. | CALA | Common Stock, par value $0.0001 ("Common Stock") | I | 10,2500 | 487.804 | 5.000 | 4.122.873 | ||||
| 2017-03-15 | 2017-03-13 | 4 | Hecht Curtis | CALA | Common Stock | D | 14,0000 | -600 | -8 | 15.560 | ||||
| 2017-03-06 | 2017-03-02 | 4 | Hecht Curtis | CALA | Common Stock | D | 12,0000 | -550 | -7 | 16.160 | ||||
| 2017-01-06 | 3 | Parlati Francesco | CALA | Common Stock | D | 24.764 | ||||||||
| 2017-01-06 | 3 | Parlati Francesco | CALA | Common Stock | D | 24.764 | ||||||||
| 2017-01-06 | 3 | Wong Stephanie By Trust | CALA | Common Stock | I | 28.204 | ||||||||
| 2017-01-06 | 3 | Wong Stephanie By Trust | CALA | Common Stock | I | 28.204 | ||||||||
| 2016-12-20 | 2016-12-19 | 4 | Molineaux Susan By Spouse | CALA | Employee Stock Option (Right to Buy) | I | 2,64 | -4.749 | 9.498 | |||||
| 2016-12-20 | 2016-12-19 | 4 | Molineaux Susan By Spouse | CALA | Employee Stock Option (Right to Buy) | I | 0,96 | -5.418 | 6.502 | |||||
| 2016-12-20 | 2016-12-19 | 4 | Molineaux Susan | CALA | Employee Stock Option (Right to Buy) | D | 2,64 | -15.627 | 42.021 | |||||
| 2016-12-20 | 2016-12-19 | 4 | Molineaux Susan | CALA | Employee Stock Option (Right to Buy) | D | 0,96 | -6.306 | 7.568 | |||||
| 2016-12-20 | 2016-12-19 | 4 | Molineaux Susan | CALA | Common Stock | D | 2,6400 | 15.627 | 41 | 23.810 | ||||
| 2016-12-20 | 2016-12-19 | 4 | Molineaux Susan | CALA | Common Stock | D | 0,9600 | 6.306 | 6 | 8.183 | ||||
| 2016-12-20 | 2016-12-19 | 4 | Molineaux Christopher By Spouse | CALA | Employee Stock Option (Right to Buy) | I | 2,64 | -15.627 | 42.021 | |||||
| 2016-12-20 | 2016-12-19 | 4 | Molineaux Christopher By Spouse | CALA | Employee Stock Option (Right to Buy) | I | 0,96 | -6.306 | 7.568 | |||||
| 2016-12-20 | 2016-12-19 | 4 | Molineaux Christopher | CALA | Employee Stock Option (Right to Buy) | D | 2,64 | -4.749 | 9.498 | |||||
| 2016-12-20 | 2016-12-19 | 4 | Molineaux Christopher | CALA | Employee Stock Option (Right to Buy) | D | 0,96 | -5.418 | 6.502 | |||||
| 2016-12-20 | 2016-12-19 | 4 | Molineaux Christopher | CALA | Common Stock | D | 2,6400 | 4.749 | 13 | 12.044 | ||||
| 2016-12-20 | 2016-12-19 | 4 | Molineaux Christopher | CALA | Common Stock | D | 0,9600 | 5.418 | 5 | 7.295 | ||||
| 2016-12-01 | 2016-11-29 | 4 | Waddill William D. | CALA | Employee Stock Option (Right to Buy) | D | 3,35 | 75.000 | 75.000 | |||||
| 2016-12-01 | 2016-11-29 | 4 | Molineaux Susan | CALA | Employee Stock Option (Right to Buy) | D | 3,35 | 165.000 | 165.000 | |||||
| 2016-12-01 | 2016-11-29 | 4 | Sjogren Eric | CALA | Employee Stock Option (Right to Buy) | D | 3,35 | 75.000 | 75.000 | |||||
| 2016-12-01 | 2016-11-29 | 4 | Molineaux Christopher | CALA | Employee Stock Option (Right to Buy) | D | 3,35 | 75.000 | 75.000 | |||||
| 2016-12-01 | 2016-11-29 | 4 | Hecht Curtis | CALA | Employee Stock Option (Right to Buy) | D | 3,35 | 75.000 | 75.000 | |||||
| 2016-12-01 | 2016-11-29 | 4 | Bennett Mark K | CALA | Employee Stock Option (Right to Buy) | D | 3,35 | 56.250 | 56.250 | |||||
| 2016-12-01 | 2016-11-29 | 4 | Orford Keith | CALA | Stock Option (Right to Buy) | D | 3,35 | 75.000 | 75.000 | |||||
| 2016-11-17 | 2016-11-16 | 4 | ADAGE CAPITAL PARTNERS GP, L.L.C. | CALA | Common Stock, par value $0.0001 ("Common Stock") | I | 3,1500 | 500.000 | 1.575 | 3.635.069 | ||||
| 2016-10-03 | 2016-09-29 | 4 | Waddill William D. | CALA | Common Stock | D | -17.485 | 17.485 | ||||||
| 2016-08-11 | 3 | JONES SUZY | CALA | Common Stock | D | 14.394 | ||||||||
| 2016-08-11 | 3 | JONES SUZY | CALA | Common Stock | D | 14.394 | ||||||||
| 2016-08-11 | 2016-08-09 | 4 | JONES SUZY | CALA | Stock Option (Right to Buy) | D | 3,26 | 22.000 | 22.000 | |||||
| 2016-08-10 | 2016-08-08 | 4 | Hecht Curtis | CALA | Common Stock | D | 3.085 | 14.210 | ||||||
| 2016-07-21 | 2016-07-20 | 4 | Molineaux Susan By Spouse | CALA | Employee Stock Option (Right to Buy) | I | 2,64 | -4.749 | 14.247 | |||||
| 2016-07-21 | 2016-07-20 | 4 | Molineaux Susan By Spouse | CALA | Employee Stock Option (Right to Buy) | I | 0,96 | -7.586 | 11.920 | |||||
| 2016-07-21 | 2016-07-20 | 4 | Molineaux Susan | CALA | Employee Stock Option (Right to Buy) | D | 2,64 | -16.146 | 47.919 | |||||
| 2016-07-21 | 2016-07-20 | 4 | Molineaux Susan | CALA | Employee Stock Option (Right to Buy) | D | 0,96 | -8.829 | 13.874 | |||||
| 2016-07-21 | 2016-07-20 | 4 | Molineaux Susan | CALA | Employee Stock Option (Right to Buy) | D | 0,48 | -4.410 | 0 | |||||
| 2016-07-21 | 2016-07-20 | 4 | Molineaux Susan | CALA | Common Stock | D | 2,6400 | 16.146 | 43 | 31.885 | ||||
| 2016-07-21 | 2016-07-20 | 4 | Molineaux Susan | CALA | Common Stock | D | 0,9600 | 8.829 | 8 | 15.739 | ||||
| 2016-07-21 | 2016-07-20 | 4 | Molineaux Susan | CALA | Common Stock | D | 0,4800 | 4.410 | 2 | 6.910 | ||||
| 2016-07-21 | 2016-07-20 | 4 | Molineaux Christopher By Spouse | CALA | Employee Stock Option (Right to Buy) | I | 2,64 | -16.146 | 47.919 | |||||
| 2016-07-21 | 2016-07-20 | 4 | Molineaux Christopher By Spouse | CALA | Employee Stock Option (Right to Buy) | I | 0,96 | -8.829 | 13.874 | |||||
| 2016-07-21 | 2016-07-20 | 4 | Molineaux Christopher By Spouse | CALA | Employee Stock Option (Right to Buy) | I | 0,48 | -4.410 | 0 | |||||
| 2016-07-21 | 2016-07-20 | 4 | Molineaux Christopher | CALA | Employee Stock Option (Right to Buy) | D | 2,64 | -4.749 | 14.247 | |||||
| 2016-07-21 | 2016-07-20 | 4 | Molineaux Christopher | CALA | Employee Stock Option (Right to Buy) | D | 0,96 | -7.586 | 11.920 | |||||
| 2016-07-21 | 2016-07-20 | 4 | Molineaux Christopher | CALA | Common Stock | D | 2,6400 | 4.749 | 13 | 14.835 | ||||
| 2016-07-21 | 2016-07-20 | 4 | Molineaux Christopher | CALA | Common Stock | D | 0,9600 | 7.586 | 7 | 10.086 | ||||
| 2016-06-16 | 2016-06-14 | 4 | PAKIANATHAN DEEPIKA | CALA | Stock Option (Right to Buy) | D | 4,76 | 11.000 | 11.000 | |||||
| 2016-06-16 | 2016-06-14 | 4 | Wolff Henry Ward | CALA | Stock Option (Right to Buy) | D | 4,76 | 11.000 | 11.000 | |||||
| 2016-06-16 | 2016-06-14 | 4 | George Jean | CALA | Stock Option (Right to Buy) | D | 4,76 | 11.000 | 11.000 | |||||
| 2016-06-16 | 2016-06-14 | 4 | DRACHMAN JONATHAN G | CALA | Stock Option (Right to Buy) | D | 4,76 | 11.000 | 11.000 | |||||
| 2016-06-16 | 2016-06-14 | 4 | AGARWAL SUNIL | CALA | Stock Option (Right to Buy) | D | 4,76 | 11.000 | 11.000 | |||||
| 2016-05-03 | 3 | Orford Keith | CALA | Common Stock | D | 4.240 | ||||||||
| 2016-05-03 | 3 | Orford Keith | CALA | Common Stock | D | 4.240 | ||||||||
| 2016-05-03 | 2016-05-02 | 4 | Orford Keith | CALA | Stock Option (Right to Buy) | D | 5,33 | 5.000 | 5.000 | |||||
| 2016-01-21 | 2016-01-19 | 4 | Bennett Mark K | CALA | Employee Stock Option (Right to Buy) | D | 4,71 | 70.000 | 70.000 | |||||
| 2016-01-21 | 2016-01-19 | 4 | Sjogren Eric | CALA | Employee Stock Option (Right to Buy) | D | 4,71 | 70.000 | 70.000 | |||||
| 2016-01-21 | 2016-01-19 | 4 | Hecht Curtis | CALA | Employee Stock Option (Right to Buy) | D | 4,71 | 32.500 | 32.500 | |||||
| 2016-01-21 | 2016-01-19 | 4 | Molineaux Susan | CALA | Employee Stock Option (Right to Buy) | D | 4,71 | 185.000 | 185.000 | |||||
| 2016-01-21 | 2016-01-19 | 4 | Molineaux Christopher | CALA | Employee Stock Option (Right to Buy) | D | 4,71 | 70.000 | 70.000 | |||||
| 2016-01-21 | 2016-01-19 | 4 | Waddill William D. | CALA | Employee Stock Option (Right to Buy) | D | 4,71 | 70.000 | 70.000 | |||||
| 2015-12-31 | 2015-12-29 | 4 | Bennett Mark K | CALA | Stock Option (Right to Buy) | D | 2,64 | -4.749 | 18.998 | |||||
| 2015-12-31 | 2015-12-29 | 4 | Bennett Mark K | CALA | Stock Option (Right to Buy) | D | 0,96 | -2.835 | 8.034 | |||||
| 2015-12-31 | 2015-12-29 | 4 | Bennett Mark K | CALA | Stock Option (Right to Buy) | D | 0,48 | -1.612 | 807 | |||||
| 2015-12-31 | 2015-12-29 | 4 | Bennett Mark K | CALA | Stock Option (Right to Buy) | D | 0,48 | -1.217 | 0 | |||||
| 2015-12-31 | 2015-12-29 | 4 | Bennett Mark K | CALA | Common Stock | D | 2,6400 | 4.749 | 13 | 10.413 | ||||
| 2015-12-31 | 2015-12-29 | 4 | Bennett Mark K | CALA | Common Stock | D | 0,9600 | 2.835 | 3 | 5.664 | ||||
| 2015-12-31 | 2015-12-29 | 4 | Bennett Mark K | CALA | Common Stock | D | 0,4800 | 1.612 | 1 | 2.829 | ||||
| 2015-12-31 | 2015-12-29 | 4 | Bennett Mark K | CALA | Common Stock | D | 0,4800 | 1.217 | 1 | 1.217 | ||||
| 2015-12-23 | 2015-12-21 | 4 | Molineaux Susan By Spouse | CALA | Employee Stock Option (Right to Buy) | I | 2,64 | -4.749 | 18.996 | |||||
| 2015-12-23 | 2015-12-21 | 4 | Molineaux Susan By Spouse | CALA | Employee Stock Option (Right to Buy) | I | 0,96 | -5.418 | 19.506 | |||||
| 2015-12-23 | 2015-12-21 | 4 | Molineaux Susan | CALA | Employee Stock Option (Right to Buy) | D | 2,64 | -11.640 | 73.794 | |||||
| 2015-12-23 | 2015-12-21 | 4 | Molineaux Susan | CALA | Employee Stock Option (Right to Buy) | D | 0,96 | -6.306 | 22.703 | |||||
| 2015-12-23 | 2015-12-21 | 4 | Molineaux Susan | CALA | Employee Stock Option (Right to Buy) | D | 0,48 | -5.512 | 4.410 | |||||
| 2015-12-23 | 2015-12-21 | 4 | Molineaux Susan | CALA | Employee Stock Option (Right to Buy) | D | 0,48 | -4.367 | 0 | |||||
| 2015-12-23 | 2015-12-21 | 4 | Molineaux Susan | CALA | Common Stock | D | 2,6400 | 11.640 | 31 | 109.112 | ||||
| 2015-12-23 | 2015-12-21 | 4 | Molineaux Susan | CALA | Common Stock | D | 0,9600 | 6.306 | 6 | 97.472 | ||||
| 2015-12-23 | 2015-12-21 | 4 | Molineaux Susan | CALA | Common Stock | D | 0,4800 | 5.512 | 3 | 91.166 | ||||
| 2015-12-23 | 2015-12-21 | 4 | Molineaux Susan | CALA | Common Stock | D | 0,4800 | 4.367 | 2 | 85.654 | ||||
| 2015-12-23 | 2015-12-21 | 4 | Molineaux Christopher By Spouse | CALA | Employee Stock Option (Right to Buy) | I | 2,64 | -11.640 | 73.794 | |||||
| 2015-12-23 | 2015-12-21 | 4 | Molineaux Christopher By Spouse | CALA | Employee Stock Option (Right to Buy) | I | 0,96 | -6.306 | 22.703 | |||||
| 2015-12-23 | 2015-12-21 | 4 | Molineaux Christopher By Spouse | CALA | Employee Stock Option (Right to Buy) | I | 0,48 | -5.512 | 4.410 | |||||
| 2015-12-23 | 2015-12-21 | 4 | Molineaux Christopher By Spouse | CALA | Employee Stock Option (Right to Buy) | I | 0,48 | -4.367 | 0 | |||||
| 2015-12-23 | 2015-12-21 | 4 | Molineaux Christopher | CALA | Employee Stock Option (Right to Buy) | D | 2,64 | -4.749 | 18.996 | |||||
| 2015-12-23 | 2015-12-21 | 4 | Molineaux Christopher | CALA | Employee Stock Option (Right to Buy) | D | 0,96 | -5.418 | 19.506 | |||||
| 2015-12-23 | 2015-12-21 | 4 | Molineaux Christopher | CALA | Common Stock | D | 2,6400 | 4.749 | 13 | 39.542 | ||||
| 2015-12-23 | 2015-12-21 | 4 | Molineaux Christopher | CALA | Common Stock | D | 0,9600 | 5.418 | 5 | 34.793 | ||||
| 2015-11-18 | 2015-11-16 | 4 | Hecht Curtis | CALA | Common Stock | D | 6,5820 | -970 | -6 | 8.625 | ||||
| 2015-09-30 | 3 | AGARWAL SUNIL | CALA | No securities beneficially owned | D | 0 | ||||||||
| 2015-09-30 | 2015-09-29 | 4 | AGARWAL SUNIL | CALA | Stock Option (Right to Buy) | D | 5,00 | 22.000 | 22.000 | |||||
| 2015-09-24 | 2015-09-23 | 4 | ADAGE CAPITAL PARTNERS GP, L.L.C. | CALA | Common Stock | I | 6,0687 | 40.168 | 244 | 3.135.069 | ||||
| 2015-09-24 | 2015-09-22 | 4 | ADAGE CAPITAL PARTNERS GP, L.L.C. | CALA | Common Stock | I | 6,0033 | 41.800 | 251 | 3.094.901 | ||||
| 2015-09-24 | 2015-09-22 | 4 | ADAGE CAPITAL PARTNERS GP, L.L.C. | CALA | Common Stock, par value $0.0001 ("Common Stock") | I | 5,9977 | 25.000 | 150 | 3.053.101 | ||||
| 2015-09-08 | 2015-09-04 | 4 | ADAGE CAPITAL PARTNERS GP, L.L.C. | CALA | Common Stock | I | 5,9500 | 2.300 | 14 | 3.028.101 | ||||
| 2015-09-08 | 2015-09-03 | 4 | ADAGE CAPITAL PARTNERS GP, L.L.C. | CALA | Common Stock, par value $0.0001 ("Common Stock") | I | 5,9300 | 88.000 | 522 | 3.025.801 | ||||
| 2015-08-28 | 2015-08-28 | 4 | ADAGE CAPITAL PARTNERS GP, L.L.C. | CALA | Common Stock | I | 5,5800 | 22.000 | 123 | 2.937.801 | ||||
| 2015-08-28 | 2015-08-28 | 4 | ADAGE CAPITAL PARTNERS GP, L.L.C. | CALA | Common Stock | I | 5,5500 | 20.700 | 115 | 2.915.801 | ||||
| 2015-08-28 | 2015-08-27 | 4 | ADAGE CAPITAL PARTNERS GP, L.L.C. | CALA | Common Stock | I | 5,3500 | 32.400 | 173 | 2.895.101 | ||||
| 2015-08-28 | 2015-08-27 | 4 | ADAGE CAPITAL PARTNERS GP, L.L.C. | CALA | Common Stock | I | 5,1700 | 29.089 | 150 | 2.862.701 | ||||
| 2015-08-28 | 2015-08-27 | 4 | ADAGE CAPITAL PARTNERS GP, L.L.C. | CALA | Common Stock | I | 5,5800 | 19.578 | 109 | 2.833.612 | ||||
| 2015-08-28 | 2015-08-27 | 4 | ADAGE CAPITAL PARTNERS GP, L.L.C. | CALA | Common Stock | I | 5,4300 | 6.253 | 34 | 2.814.034 | ||||
| 2015-08-28 | 2015-08-27 | 4 | ADAGE CAPITAL PARTNERS GP, L.L.C. | CALA | Common Stock | I | 5,4100 | 9.848 | 53 | 2.807.781 | ||||
| 2015-08-28 | 2015-08-26 | 4 | ADAGE CAPITAL PARTNERS GP, L.L.C. | CALA | Common Stock | I | 4,6500 | 32.058 | 149 | 2.797.933 | ||||
| 2015-08-28 | 2015-08-26 | 4 | ADAGE CAPITAL PARTNERS GP, L.L.C. | CALA | Common Stock, par value $0.0001 ("Common Stock") | I | 4,7000 | 200 | 1 | 2.765.875 | ||||
| 2015-08-24 | 2015-08-20 | 4 | Hecht Curtis | CALA | Stock Option (Right to Buy) | D | 2,64 | -2.000 | 43.378 | |||||
| 2015-08-24 | 2015-08-20 | 4 | Hecht Curtis | CALA | Common Stock | D | 2,6400 | 2.000 | 5 | 8.625 | ||||
| 2015-07-16 | 2015-07-14 | 4 | Waddill William D. | CALA | Stock Option (Right to Buy) | D | 2,64 | -13.125 | 61.880 | |||||
| 2015-07-16 | 2015-07-14 | 4 | Waddill William D. | CALA | Common Stock | D | 2,6400 | 13.125 | 35 | 15.625 | ||||
| 2015-07-15 | 2015-07-13 | 4 | Molineaux Susan By Spouse | CALA | Stock Option (Right to Buy) | I | 2,64 | -10.288 | 23.745 | |||||
| 2015-07-15 | 2015-07-13 | 4 | Molineaux Susan By Spouse | CALA | Stock Option (Right to Buy) | I | 0,96 | -14.087 | 24.924 | |||||
| 2015-07-15 | 2015-07-13 | 4 | Molineaux Susan | CALA | Stock Option (Right to Buy) | D | 2,64 | -30.279 | 85.434 | |||||
| 2015-07-15 | 2015-07-13 | 4 | Molineaux Susan | CALA | Stock Option (Right to Buy) | D | 0,96 | -16.396 | 29.009 | |||||
| 2015-07-15 | 2015-07-13 | 4 | Molineaux Susan | CALA | Stock Option (Right to Buy) | D | 0,48 | -14.330 | 9.922 | |||||
| 2015-07-15 | 2015-07-13 | 4 | Molineaux Susan | CALA | Stock Option (Right to Buy) | D | 0,48 | -15.282 | 4.367 | |||||
| 2015-07-15 | 2015-07-13 | 4 | Molineaux Susan | CALA | Common Stock | D | 2,6400 | 30.279 | 80 | 78.787 | ||||
| 2015-07-15 | 2015-07-13 | 4 | Molineaux Susan | CALA | Common Stock | D | 0,9600 | 16.396 | 16 | 48.508 | ||||
| 2015-07-15 | 2015-07-13 | 4 | Molineaux Susan | CALA | Common Stock | D | 0,4800 | 14.330 | 7 | 32.112 | ||||
| 2015-07-15 | 2015-07-13 | 4 | Molineaux Susan | CALA | Common Stock | D | 0,4800 | 15.282 | 7 | 17.782 | ||||
| 2015-07-15 | 2015-07-13 | 4 | Molineaux Christopher By Spouse | CALA | Stock Option (Right to Buy) | I | 2,64 | -30.279 | 85.434 | |||||
| 2015-07-15 | 2015-07-13 | 4 | Molineaux Christopher By Spouse | CALA | Stock Option (Right to Buy) | I | 0,96 | -16.396 | 29.009 | |||||
| 2015-07-15 | 2015-07-13 | 4 | Molineaux Christopher By Spouse | CALA | Stock Option (Right to Buy) | I | 0,48 | -14.330 | 9.922 | |||||
| 2015-07-15 | 2015-07-13 | 4 | Molineaux Christopher By Spouse | CALA | Stock Option (Right to Buy) | I | 0,48 | -15.282 | 4.367 | |||||
| 2015-07-15 | 2015-07-13 | 4 | Molineaux Christopher | CALA | Stock Option (Right to Buy) | D | 2,64 | -10.288 | 23.745 | |||||
| 2015-07-15 | 2015-07-13 | 4 | Molineaux Christopher | CALA | Stock Option (Right to Buy) | D | 0,96 | -14.087 | 24.924 | |||||
| 2015-07-15 | 2015-07-13 | 4 | Molineaux Christopher | CALA | Common Stock | D | 2,6400 | 10.288 | 27 | 26.875 | ||||
| 2015-07-15 | 2015-07-13 | 4 | Molineaux Christopher | CALA | Common Stock | D | 0,9600 | 14.087 | 14 | 16.587 | ||||
| 2015-07-10 | 2015-07-08 | 4 | Bennett Mark K | CALA | Stock Option (Right to Buy) | D | 2,64 | -7.912 | 23.747 | |||||
| 2015-07-10 | 2015-07-08 | 4 | Bennett Mark K | CALA | Stock Option (Right to Buy) | D | 0,96 | -4.726 | 10.869 | |||||
| 2015-07-10 | 2015-07-08 | 4 | Bennett Mark K | CALA | Stock Option (Right to Buy) | D | 0,48 | -2.688 | 2.419 | |||||
| 2015-07-10 | 2015-07-08 | 4 | Bennett Mark K | CALA | Stock Option (Right to Buy) | D | 0,48 | -3.039 | 1.217 | |||||
| 2015-07-10 | 2015-07-08 | 4 | Bennett Mark K | CALA | Common Stock | D | 2,6400 | 7.912 | 21 | 19.501 | ||||
| 2015-07-10 | 2015-07-08 | 4 | Bennett Mark K | CALA | Common Stock | D | 0,9600 | 4.726 | 5 | 11.589 | ||||
| 2015-07-10 | 2015-07-08 | 4 | Bennett Mark K | CALA | Common Stock | D | 0,4800 | 2.688 | 1 | 6.863 | ||||
| 2015-07-10 | 2015-07-08 | 4 | Bennett Mark K | CALA | Common Stock | D | 0,4800 | 3.039 | 1 | 4.175 | ||||
| 2015-06-11 | 2015-06-09 | 4 | Wolff Henry Ward | CALA | Stock Option (Right to Buy) | D | 7,99 | 11.000 | 33.000 | |||||
| 2015-06-11 | 2015-06-09 | 4 | George Jean | CALA | Stock Option (Right to Buy) | D | 7,99 | 11.000 | 11.000 | |||||
| 2015-06-11 | 2015-06-09 | 4 | DRACHMAN JONATHAN G | CALA | Stock Option (Right to Buy) | D | 7,99 | 11.000 | 39.355 | |||||
| 2015-06-10 | 2015-06-09 | 4 | PAKIANATHAN DEEPIKA | CALA | Stock Option (Right to Buy) | D | 7,99 | 11.000 | 11.000 | |||||
| 2015-02-12 | 2015-02-11 | 4 | Waddill William D. | CALA | Stock Option (Right to Buy) | D | 16,40 | 45.000 | 45.000 | |||||
| 2015-02-12 | 2015-02-11 | 4 | Molineaux Susan | CALA | Stock Option (Right to Buy) | D | 16,40 | 227.346 | 227.346 | |||||
| 2015-02-12 | 2015-02-11 | 4 | Bennett Mark K | CALA | Stock Option (Right to Buy) | D | 16,40 | 45.000 | 45.000 | |||||
| 2015-02-12 | 2015-02-11 | 4 | Hecht Curtis | CALA | Stock Option (Right to Buy) | D | 16,40 | 25.000 | 25.000 | |||||
| 2015-02-12 | 2015-02-11 | 4 | Molineaux Christopher | CALA | Stock Option (Right to Buy) | D | 16,40 | 45.000 | 45.000 | |||||
| 2015-02-12 | 2015-02-11 | 4 | Sjogren Eric | CALA | Stock Option (Right to Buy) | D | 16,40 | 45.000 | 45.000 | |||||
| 2014-12-18 | 2014-12-16 | 4 | Waddill William D. | CALA | Stock Option (Right to Buy) | D | 7,20 | 1.171 | 17.569 | |||||
| 2014-12-18 | 2014-12-16 | 4 | Waddill William D. | CALA | Stock Option (Right to Buy) | D | 2,64 | 5.626 | 75.005 | |||||
| 2014-12-18 | 2014-12-16 | 4 | Waddill William D. By Trust | CALA | Common Stock | I | 7,2000 | 1.171 | 8 | 16.172 | ||||
| 2014-12-18 | 2014-12-16 | 4 | Waddill William D. By Trust | CALA | Common Stock | I | 2,6400 | 5.626 | 15 | 15.001 | ||||
| 2014-12-09 | 3 | Wolff Henry Ward | CALA | No securities beneficially owned | D | 0 | ||||||||
| 2014-12-09 | 2014-12-02 | 4 | Wolff Henry Ward | CALA | Stock Option (Right to Buy) | D | 9,64 | 22.000 | 22.000 | |||||
| 2014-10-15 | 2014-10-15 | 4 | ADAGE CAPITAL PARTNERS GP, L.L.C. | CALA | Common Stock | I | 6,8000 | 25.000 | 170 | 2.765.675 | ||||
| 2014-10-15 | 2014-10-15 | 4 | ADAGE CAPITAL PARTNERS GP, L.L.C. | CALA | Common Stock | I | 7,2500 | 13.000 | 94 | 2.740.675 | ||||
| 2014-10-15 | 2014-10-14 | 4 | ADAGE CAPITAL PARTNERS GP, L.L.C. | CALA | Common Stock | I | 6,9900 | 25.000 | 175 | 2.727.375 | ||||
| 2014-10-15 | 2014-10-14 | 4 | ADAGE CAPITAL PARTNERS GP, L.L.C. | CALA | Common Stock | I | 7,0000 | 30.000 | 210 | 2.702.375 | ||||
| 2014-10-15 | 2014-10-13 | 4 | ADAGE CAPITAL PARTNERS GP, L.L.C. | CALA | Common Stock, par value $0.0001 ("Common Stock") | I | 6,9400 | 88.700 | 616 | 2.672.375 | ||||
| 2014-10-09 | 2014-10-07 | 4 | PAKIANATHAN DEEPIKA Delphi BioInvestments VIII, L.P. | CALA | Series D Preferred Stock | I | 7.282 | 0 | ||||||
| 2014-10-09 | 2014-10-07 | 4 | PAKIANATHAN DEEPIKA Delphi Ventures VIII, L.P. | CALA | Series D Preferred Stock | I | 745.825 | 0 | ||||||
| 2014-10-09 | 2014-10-07 | 4 | PAKIANATHAN DEEPIKA Delphi BioInvestments VIII, L.P. | CALA | Series C Preferred Stock | I | 7.228 | 0 | ||||||
| 2014-10-09 | 2014-10-07 | 4 | PAKIANATHAN DEEPIKA Delphi Ventures VIII, L.P. | CALA | Series C Preferred Stock | I | 740.312 | 0 | ||||||
| 2014-10-09 | 2014-10-07 | 4 | PAKIANATHAN DEEPIKA Delphi BioInvestments VIII, L.P. | CALA | Series B Preferred Stock | I | 4.053 | 0 | ||||||
| 2014-10-09 | 2014-10-07 | 4 | PAKIANATHAN DEEPIKA Delphi Ventures VIII, L.P. | CALA | Series B Preferred Stock | I | 415.128 | 0 | ||||||
| 2014-10-09 | 2014-10-07 | 4 | PAKIANATHAN DEEPIKA Delphi BioInvestments VIII, L.P. | CALA | Series A Preferred Stock | I | 66 | 0 | ||||||
| 2014-10-09 | 2014-10-07 | 4 | PAKIANATHAN DEEPIKA Delphi Ventures VIII, L.P. | CALA | Series A Preferred Stock | I | 6.808 | 0 | ||||||
| 2014-10-09 | 2014-10-07 | 4 | PAKIANATHAN DEEPIKA Delphi BioInvestments VIII, L.P. | CALA | Common Stock | I | 10,0000 | 4.835 | 48 | 23.464 | ||||
| 2014-10-09 | 2014-10-07 | 4 | PAKIANATHAN DEEPIKA Delphi Ventures VIII, L.P. | CALA | Common Stock | I | 10,0000 | 495.165 | 4.952 | 2.403.238 | ||||
| 2014-10-09 | 2014-10-07 | 4 | PAKIANATHAN DEEPIKA Delphi BioInvestments VIII, L.P. | CALA | Common Stock | I | 18.629 | 18.629 | ||||||
| 2014-10-09 | 2014-10-07 | 4 | PAKIANATHAN DEEPIKA Delphi Ventures VIII, L.P. | CALA | Common Stock | I | 1.908.073 | 1.908.073 | ||||||
| 2014-10-09 | 2014-10-07 | 4 | George Jean | CALA | SERIES D PREFERRED STOCK | I | 634.195 | 0 | ||||||
| 2014-10-09 | 2014-10-07 | 4 | George Jean | CALA | SERIES C PREFERRED STOCK | I | 747.540 | 0 | ||||||
| 2014-10-09 | 2014-10-07 | 4 | George Jean | CALA | SERIES B PREFERRED STOCK | I | 419.181 | 0 | ||||||
| 2014-10-09 | 2014-10-07 | 4 | George Jean | CALA | SERIES A PREFERRED STOCK | I | 9.166 | 0 | ||||||
| 2014-10-09 | 2014-10-07 | 4 | George Jean By Partnership | CALA | COMMON STOCK | I | 10,0000 | 300.000 | 3.000 | 2.110.082 | ||||
| 2014-10-09 | 2014-10-07 | 4 | George Jean By Partnership | CALA | COMMON STOCK | I | 1.810.082 | 1.810.082 | ||||||
| 2014-10-09 | 2014-10-07 | 4 | Christoffersen Ralph E | CALA | SERIES D PREFERRED STOCK | I | 634.195 | 0 | ||||||
| 2014-10-09 | 2014-10-07 | 4 | Christoffersen Ralph E | CALA | SERIES C PREFERRED STOCK | I | 747.540 | 0 | ||||||
| 2014-10-09 | 2014-10-07 | 4 | Christoffersen Ralph E | CALA | SERIES B PREFERRED STOCK | I | 419.181 | 0 | ||||||
| 2014-10-09 | 2014-10-07 | 4 | Christoffersen Ralph E | CALA | SERIES A PREFERRED STOCK | I | 10.999 | 0 | ||||||
| 2014-10-09 | 2014-10-07 | 4 | Christoffersen Ralph E By Partnership | CALA | COMMON STOCK | I | 10,0000 | 350.000 | 3.500 | 2.161.915 | ||||
| 2014-10-09 | 2014-10-07 | 4 | Christoffersen Ralph E By Partnership | CALA | COMMON STOCK | I | 1.811.915 | 1.811.915 | ||||||
| 2014-10-09 | 2014-10-07 | 4 | MORGENTHALER VENTURE PARTNERS IX LP | CALA | SERIES D PREFERRED STOCK | D | 634.195 | 0 | ||||||
| 2014-10-09 | 2014-10-07 | 4 | MORGENTHALER VENTURE PARTNERS IX LP | CALA | SERIES C PREFERRED STOCK | D | 747.540 | 0 | ||||||
| 2014-10-09 | 2014-10-07 | 4 | MORGENTHALER VENTURE PARTNERS IX LP | CALA | SERIES B PREFERRED STOCK | D | 419.181 | 0 | ||||||
| 2014-10-09 | 2014-10-07 | 4 | MORGENTHALER VENTURE PARTNERS IX LP | CALA | SERIES A PREFERRED STOCK | D | 10.999 | 0 | ||||||
| 2014-10-09 | 2014-10-07 | 4 | MORGENTHALER VENTURE PARTNERS IX LP | CALA | COMMON STOCK | D | 10,0000 | 350.000 | 3.500 | 2.161.915 | ||||
| 2014-10-09 | 2014-10-07 | 4 | MORGENTHALER VENTURE PARTNERS IX LP | CALA | COMMON STOCK | D | 10,0000 | 1.811.915 | 18.119 | 1.811.915 | ||||
| 2014-10-09 | 2014-10-07 | 4 | Delphi Management Partners VIII, L.L.C. Delphi BioInvestments VIII, L.P. | CALA | Series D Preferred Stock | I | 7.282 | 0 | ||||||
| 2014-10-09 | 2014-10-07 | 4 | Delphi Management Partners VIII, L.L.C. Delphi Ventures VIII, L.P. | CALA | Series D Preferred Stock | I | 745.825 | 0 | ||||||
| 2014-10-09 | 2014-10-07 | 4 | Delphi Management Partners VIII, L.L.C. Delphi BioInvestments VIII, L.P. | CALA | Series C Preferred Stock | I | 7.228 | 0 | ||||||
| 2014-10-09 | 2014-10-07 | 4 | Delphi Management Partners VIII, L.L.C. Delphi Ventures VIII, L.P. | CALA | Series C Preferred Stock | I | 740.312 | 0 | ||||||
| 2014-10-09 | 2014-10-07 | 4 | Delphi Management Partners VIII, L.L.C. Delphi BioInvestments VIII, L.P. | CALA | Series B Preferred Stock | I | 4.053 | 0 | ||||||
| 2014-10-09 | 2014-10-07 | 4 | Delphi Management Partners VIII, L.L.C. Delphi Ventures VIII, L.P. | CALA | Series B Preferred Stock | I | 415.128 | 0 | ||||||
| 2014-10-09 | 2014-10-07 | 4 | Delphi Management Partners VIII, L.L.C. Delphi BioInvestments VIII, L.P. | CALA | Series A Preferred Stock | I | 66 | 0 | ||||||
| 2014-10-09 | 2014-10-07 | 4 | Delphi Management Partners VIII, L.L.C. Delphi Ventures VIII, L.P. | CALA | Series A Preferred Stock | I | 6.808 | 0 | ||||||
| 2014-10-09 | 2014-10-07 | 4 | Delphi Management Partners VIII, L.L.C. Delphi BioInvestments VIII, L.P. | CALA | Common Stock | I | 10,0000 | 4.835 | 48 | 23.464 | ||||
| 2014-10-09 | 2014-10-07 | 4 | Delphi Management Partners VIII, L.L.C. Delphi Ventures VIII, L.P. | CALA | Common Stock | I | 10,0000 | 495.165 | 4.952 | 2.403.238 | ||||
| 2014-10-09 | 2014-10-07 | 4 | Delphi Management Partners VIII, L.L.C. Delphi BioInvestments VIII, L.P. | CALA | Common Stock | I | 18.629 | 18.629 | ||||||
| 2014-10-09 | 2014-10-07 | 4 | Delphi Management Partners VIII, L.L.C. Delphi Ventures VIII, L.P. | CALA | Common Stock | I | 1.908.073 | 1.908.073 | ||||||
| 2014-10-09 | 2014-10-07 | 4 | Advanced Technology Ventures VIII LP | CALA | SERIES D PREFERRED STOCK | D | 634.195 | 0 | ||||||
| 2014-10-09 | 2014-10-07 | 4 | Advanced Technology Ventures VIII LP | CALA | SERIES C PREFERRED STOCK | D | 747.540 | 0 | ||||||
| 2014-10-09 | 2014-10-07 | 4 | Advanced Technology Ventures VIII LP | CALA | SERIES B PREFERRED STOCK | D | 419.181 | 0 | ||||||
| 2014-10-09 | 2014-10-07 | 4 | Advanced Technology Ventures VIII LP | CALA | SERIES A PREFERRED STOCK | D | 9.166 | 0 | ||||||
| 2014-10-09 | 2014-10-07 | 4 | Advanced Technology Ventures VIII LP | CALA | COMMON STOCK | D | 10,0000 | 300.000 | 3.000 | 2.110.082 | ||||
| 2014-10-09 | 2014-10-07 | 4 | Advanced Technology Ventures VIII LP | CALA | COMMON STOCK | D | 1.810.082 | 1.810.082 | ||||||
| 2014-10-03 | 2014-10-01 | 4 | ADAGE CAPITAL PARTNERS GP, L.L.C. | CALA | Common Stock, par value $0.0001 ("Common Stock") | I | 10,0000 | 800.000 | 8.000 | 2.583.675 | ||||
| 2014-10-01 | 3 | Waddill William D. By Trust | CALA | COMMON STOCK | I | 18.750 | ||||||||
| 2014-10-01 | 3 | Waddill William D. By Trust | CALA | COMMON STOCK | I | 18.750 | ||||||||
| 2014-10-01 | 3 | Hecht Curtis | CALA | COMMON STOCK | D | 8.250 | ||||||||
| 2014-10-01 | 3 | Hecht Curtis | CALA | COMMON STOCK | D | 8.250 | ||||||||
| 2014-10-01 | 3 | Molineaux Susan | CALA | Common Stock | D | 128.962 | ||||||||
| 2014-10-01 | 3 | Molineaux Susan By Trust | CALA | Common Stock | I | 224.924 | ||||||||
| 2014-10-01 | 3 | Molineaux Susan | CALA | Common Stock | D | 128.962 | ||||||||
| 2014-10-01 | 3 | Molineaux Susan By Trust | CALA | Common Stock | I | 224.924 | ||||||||
| 2014-10-01 | 3 | Molineaux Christopher By Spouse | CALA | Common Stock | I | 128.962 | ||||||||
| 2014-10-01 | 3 | Molineaux Christopher By Trust | CALA | Common Stock | I | 224.924 | ||||||||
| 2014-10-01 | 3 | Molineaux Christopher By Trust | CALA | Common Stock | I | 224.924 | ||||||||
| 2014-10-01 | 3 | Molineaux Christopher By Spouse | CALA | Common Stock | I | 128.962 | ||||||||
| 2014-10-01 | 3 | Bennett Mark K By Trust | CALA | COMMON STOCK | I | 63.108 | ||||||||
| 2014-10-01 | 3 | Bennett Mark K By Trust | CALA | COMMON STOCK | I | 63.108 | ||||||||
| 2014-10-01 | 3 | Sjogren Eric | CALA | COMMON STOCK | D | 23.262 | ||||||||
| 2014-10-01 | 3 | Sjogren Eric | CALA | COMMON STOCK | D | 23.262 | ||||||||
| 2014-09-26 | 3 | Gross Phillip See footnotes | CALA | Common Stock, par value $0.0001 | I | 3.567.350 | ||||||||
| 2014-09-26 | 3 | Gross Phillip See footnotes | CALA | Common Stock, par value $0.0001 | I | 3.567.350 | ||||||||
| 2014-09-26 | 3 | Gross Phillip See footnotes | CALA | Common Stock, par value $0.0001 | I | 3.567.350 | ||||||||
| 2014-09-26 | 3 | Gross Phillip See footnotes | CALA | Common Stock, par value $0.0001 | I | 3.567.350 | ||||||||
| 2014-09-26 | 3 | Gross Phillip See footnotes | CALA | Common Stock, par value $0.0001 | I | 3.567.350 | ||||||||
| 2014-09-26 | 3 | Gross Phillip See footnotes | CALA | Common Stock, par value $0.0001 | I | 3.567.350 |
P
Offener Markt oder privater Kauf von nicht-derivativen oder derivativen Wertpapieren
S
Freiverkauf oder privater Verkauf von nicht-derivativen oder derivativen Wertpapieren
A
Gewährung, Vergabe oder sonstiger Erwerb von Wertpapieren des Unternehmens (z. B. eine Option)
C
Umwandlung von Derivaten
D
Verkauf oder Rückübertragung von Wertpapieren an das Unternehmen
F
Zahlung des Ausübungspreises oder der Steuerschuld mit einem Teil der vom Unternehmen erhaltenen Wertpapiere
G
Schenkung von Wertpapieren durch oder an den Insider
K
Aktien-Swaps und ähnliche Absicherungstransaktionen
M
Ausübung oder Umwandlung eines vom Unternehmen erhaltenen derivativen Wertpapiers (z. B. einer Option)
V
Eine freiwillig auf Formular 4 gemeldete Transaktion
J
Sonstige (mit einer Fußnote zur Beschreibung der Transaktion)
