| Insider-Aktien | 19.980.267 shares |
Insider-Stimmungswert
Der Insider-Stimmungswert ermittelt die Unternehmen, die von Unternehmensinsidern gekauft werden.
Es ist das Ergebnis eines ausgeklügelten quantitativen Multifaktormodells, das die Unternehmen mit der höchsten Insiderakkumulation identifiziert. Das Scoring-Modell verwendet eine Kombination aus der Nettozahl der Insiderkäufe der letzten 90 Tage, der Gesamtzahl der gekauften Aktien als Prozentsatz des Streubesitzes und der Gesamtzahl der von Insidern gehaltenen Aktien. Die Zahl reicht von 0 bis 100, wobei höhere Zahlen ein höheres Maß an Insiderkäufen anzeigen als bei anderen Unternehmen und 50 den Durchschnitt darstellt.
Aktualisierungshäufigkeit: Täglich
Führungskräfte-Stimmungswert
Der Führungskräfte-Stimmungswert findet Unternehmen, die von Führungskräften des Unternehmens gekauft werden.
Per Definition sind Führungskräfte des Unternehmens Insider, aber im Gegensatz zu anderen Insidern (10%ige Aktionäre und Vorstandsmitglieder) arbeiten Führungskräfte täglich für das Unternehmen und verwenden beim Handel ihr eigenes Geld. (10%ige Aktionäre und Vorstandsmitglieder sind oft Fondsmanager, die das Geld anderer Leute verwalten.) Daher sind Insider-Geschäfte, die von Führungskräften getätigt werden, viel bedeutender und sollten entsprechend behandelt werden.
Wie der Insider-Stimmungswert ist auch der Führungskräfte-Stimmungswert das Ergebnis eines ausgeklügelten quantitativen Multifaktormodells, das die Unternehmen mit der höchsten Führungskräftekonzentration identifiziert.
Aktualisierungshäufigkeit: Täglich
Wichtige Insider-Kennzahlen
Diese Karte zeigt, wie das Unternehmen bei verschiedenen Insider-Kennzahlen abschneidet. Der Perzentil-Rang zeigt, wie dieses Unternehmen im Vergleich zu anderen Unternehmen auf den US-Märkten abschneidet. Höhere Ränge deuten auf eine bessere Situation hin.
Es ist beispielsweise allgemein anerkannt, dass Insiderkäufe ein positiver Indikator sind, so dass Unternehmen mit mehr Insiderkäufen besser abschneiden würden als Unternehmen mit weniger Insiderkäufen (oder sogar Insiderverkäufen).
Nettoanzahl der Insider, die kaufen (Rang)
Die Nettoanzahl der Insiderkäufe ist die Gesamtzahl der Insiderkäufe abzüglich der Gesamtzahl der Insiderverkäufe in den letzten 90 Tagen. Der Perzentilrang wird hier angezeigt (Bereich von 0 bis 100%).
Prozent des Streubesitzes von Insidern gekauft (Rang)
Prozent des von Insidern gekauften Streubesitzes ist die Gesamtzahl der von Insidern gekauften Aktien abzüglich der Gesamtzahl der von Insidern in den letzten 90 Tagen verkauften Aktien, geteilt durch den gesamten Streubesitz und multipliziert mit 100.
Diagramm zum Insiderhandel
Cascadian Therapeutics, Inc. Insider-Trades sind in der folgenden Grafik dargestellt. Insider sind leitende Angestellte, Direktoren oder bedeutende Investoren in einem Unternehmen. Im Allgemeinen ist es für Insider illegal, auf der Grundlage von wesentlichen, nicht-öffentlichen Informationen mit Aktien ihrer Unternehmen zu handeln. Das bedeutet nicht, dass es für sie illegal ist, irgendwelche Geschäfte in ihren eigenen Unternehmen zu tätigen. Sie müssen jedoch alle Geschäfte der SEC über ein Formular 4 melden.
Kennzahlen zu Insiderlisten und Rentabilität
Diese Tabelle zeigt die Liste der bekannten Insider und wird automatisch aus den bei der SEC eingereichten Unterlagen erstellt. Zusätzlich zu den Namen, dem letzten Titel und der Bezeichnung als Direktor, leitender Angestellter oder 10%-iger Anteilseigner geben wir die zuletzt veröffentlichten Bestände an. Zusätzlich stellen wir, wenn möglich, die historische Handelsperformance für den Insider zur Verfügung. Die historische Handelsperformance ist ein gewichteter Durchschnitt der Performance tatsächlicher offener Kauftransaktionen, die von dem Insider getätigt wurden. Weitere Informationen zur Berechnung dieses Wertes finden Sie in diesem YouTube-Webinar.
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| Insider | Durchschnittlicher Gewinn (%) | Aktien in Besitz |
Split Angepasst |
|---|
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Erfolgsbilanz der Insiderkäufe - Kurzfristige Gewinnanalyse
In diesem Abschnitt analysieren wir die Rentabilität jedes ungeplanten Insiderkaufs, der auf dem freien Markt in CASC / Cascadian Therapeutics, Inc. getätigt wurde. Diese Analyse hilft zu verstehen, ob der Insider beständig abnormale Renditen erzielt und es sich lohnt, ihm zu folgen. Diese Analyse bezieht sich auf ein Jahr nach jedem Handel, und die Ergebnisse sind theoretisch .
Die folgende Tabelle zeigt die jüngsten Käufe am offenen Markt, die nicht Teil eines automatischen Handelsplans waren.
Bereinigter Preis ist der splitbereinigte Preis. Bereinigte Aktien sind die um den Split bereinigten Aktien.
Erfolgsbilanz von Insiderverkäufen - Kurzfristige Verlustanalyse
In diesem Abschnitt analysieren wir die kurzfristige Verlustvermeidung jedes ungeplanten Insider-Verkaufs auf dem freien Markt in CASC / Cascadian Therapeutics, Inc.. Ein konsistentes Muster der Verlustvermeidung kann darauf hindeuten, dass zukünftige Verkaufstransaktionen Kursrückgänge vorhersagen können. Diese Analyse bezieht sich auf ein Jahr nach jedem Handel, und die Ergebnisse sind theoretisch .
Die folgende Tabelle zeigt die jüngsten Verkäufe am offenen Markt, die nicht Teil eines automatischen Handelsplans waren.
Bereinigter Preis ist der splitbereinigte Preis. Bereinigte Aktien sind die um den Split bereinigten Aktien.
Transaktionshistorie
Klicken Sie auf das Link-Symbol, um den vollständigen Transaktionsverlauf anzuzeigen. Transaktionen, die im Rahmen eines automatischen Handelsplans 10b5-1 gemeldet werden, sind in der Spalte 10b-5 mit einem X gekennzeichnet.
| Datei Datum |
Handel Datum |
Form | Insider | Ticker | Wertpapier-Titel | Code | Direkt | Ausführung Preis |
Einheit Preis |
Eimheiten Verändert |
Wert Geändert (1K) |
Verbleibende Optionen |
Verbleibende Aktien |
|
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2018-03-13 | 2018-03-09 | 4 | EASTLAND JULIA MARIE | CASC | Restricted Stock Units | D | -199.000 | 0 | ||||||
| 2018-03-13 | 2018-03-09 | 4 | EASTLAND JULIA MARIE | CASC | Restricted Stock Units | D | -16.500 | 0 | ||||||
| 2018-03-13 | 2018-03-09 | 4 | EASTLAND JULIA MARIE | CASC | Restricted Stock Units | D | -11.300 | 0 | ||||||
| 2018-03-13 | 2018-03-09 | 4 | EASTLAND JULIA MARIE | CASC | Stock Option (Right to buy) | D | 3,99 | -75.000 | 0 | |||||
| 2018-03-13 | 2018-03-09 | 4 | EASTLAND JULIA MARIE | CASC | Stock Option (Right to buy) | D | 4,64 | -51.200 | 0 | |||||
| 2018-03-13 | 2018-03-09 | 4 | EASTLAND JULIA MARIE | CASC | Stock Option (Right to buy) | D | 6,90 | -50.000 | 0 | |||||
| 2018-03-13 | 2018-03-09 | 4 | EASTLAND JULIA MARIE | CASC | Stock Option (Right to buy) | D | 21,06 | -41.667 | 0 | |||||
| 2018-03-13 | 2018-03-09 | 4 | EASTLAND JULIA MARIE | CASC | Stock Option (Right to buy) | D | 10,56 | -16.667 | 0 | |||||
| 2018-03-13 | 2018-03-09 | 4 | EASTLAND JULIA MARIE | CASC | Stock Option (Right to buy) | D | 10,44 | -25.000 | 0 | |||||
| 2018-03-13 | 2018-03-09 | 4 | EASTLAND JULIA MARIE | CASC | Stock Option (Right to buy) | D | 28,44 | -8.334 | 0 | |||||
| 2018-03-13 | 2018-03-09 | 4 | EASTLAND JULIA MARIE | CASC | Stock Option (Right to buy) | D | 19,92 | -8.334 | 0 | |||||
| 2018-03-13 | 2018-03-09 | 4 | EASTLAND JULIA MARIE | CASC | Stock Option (Right to buy) | D | 41,52 | -8.334 | 0 | |||||
| 2018-03-13 | 2018-03-09 | 4 | EASTLAND JULIA MARIE | CASC | Stock Option (Right to buy) | D | 19,86 | -6.667 | 0 | |||||
| 2018-03-13 | 2018-03-09 | 4 | EASTLAND JULIA MARIE | CASC | Common Stock | D | -5.237 | 0 | ||||||
| 2018-03-13 | 2018-03-09 | 4 | HENNEY CHRISTOPHER S | CASC | Restricted Stock Units | D | -13.927 | 0 | ||||||
| 2018-03-13 | 2018-03-09 | 4 | HENNEY CHRISTOPHER S | CASC | Stock Option (Right to buy) | D | 6,36 | -25.000 | 0 | |||||
| 2018-03-13 | 2018-03-09 | 4 | HENNEY CHRISTOPHER S | CASC | Common Stock | D | -60.185 | 0 | ||||||
| 2018-03-13 | 2018-03-09 | 4 | Christianson Gary | CASC | Restricted Stock Units | D | -164.500 | 0 | ||||||
| 2018-03-13 | 2018-03-09 | 4 | Christianson Gary | CASC | Restricted Stock Units | D | -15.000 | 0 | ||||||
| 2018-03-13 | 2018-03-09 | 4 | Christianson Gary | CASC | Restricted Stock Units | D | -11.300 | 0 | ||||||
| 2018-03-13 | 2018-03-09 | 4 | Christianson Gary | CASC | Stock Option (Right to buy) | D | 3,99 | -68.000 | 0 | |||||
| 2018-03-13 | 2018-03-09 | 4 | Christianson Gary | CASC | Stock Option (Right to buy) | D | 4,64 | -51.200 | 0 | |||||
| 2018-03-13 | 2018-03-09 | 4 | Christianson Gary | CASC | Stock Option (Right to buy) | D | 6,90 | -41.667 | 0 | |||||
| 2018-03-13 | 2018-03-09 | 4 | Christianson Gary | CASC | Stock Option (Right to buy) | D | 21,06 | -41.667 | 0 | |||||
| 2018-03-13 | 2018-03-09 | 4 | Christianson Gary | CASC | Stock Option (Right to buy) | D | 10,56 | -16.667 | 0 | |||||
| 2018-03-13 | 2018-03-09 | 4 | Christianson Gary | CASC | Stock Option (Right to buy) | D | 10,44 | -25.000 | 0 | |||||
| 2018-03-13 | 2018-03-09 | 4 | Christianson Gary | CASC | Stock Option (Right to buy) | D | 28,44 | -8.334 | 0 | |||||
| 2018-03-13 | 2018-03-09 | 4 | Christianson Gary | CASC | Stock Option (Right to buy) | D | 19,92 | -8.334 | 0 | |||||
| 2018-03-13 | 2018-03-09 | 4 | Christianson Gary | CASC | Stock Option (Right to buy) | D | 41,52 | -8.334 | 0 | |||||
| 2018-03-13 | 2018-03-09 | 4 | Christianson Gary | CASC | Common Stock | D | -6.515 | 0 | ||||||
| 2018-03-13 | 2018-03-09 | 4 | Growth Equity Opportunities IV, LLC | CASC | Common Stock | D | -10.882.574 | 0 | ||||||
| 2018-03-13 | 2018-03-09 | 4 | BASKETT FOREST See Note 2 | CASC | Common Stock | I | -10.882.574 | 0 | ||||||
| 2018-03-13 | 2018-03-09 | 4 | Myers Scott Dunseth | CASC | Restricted Stock Units | D | -250.000 | 0 | ||||||
| 2018-03-13 | 2018-03-09 | 4 | Myers Scott Dunseth | CASC | Restricted Stock Units | D | -6.300 | 0 | ||||||
| 2018-03-13 | 2018-03-09 | 4 | Myers Scott Dunseth | CASC | Restricted Stock Units | D | -15.500 | 0 | ||||||
| 2018-03-13 | 2018-03-09 | 4 | Myers Scott Dunseth | CASC | Restricted Stock Units | D | -42.000 | 0 | ||||||
| 2018-03-13 | 2018-03-09 | 4 | Myers Scott Dunseth | CASC | Stock Option (Right to buy) | D | 3,99 | -60.000 | 0 | |||||
| 2018-03-13 | 2018-03-09 | 4 | Myers Scott Dunseth | CASC | Stock Option (Right to buy) | D | 4,64 | -190.000 | 0 | |||||
| 2018-03-13 | 2018-03-09 | 4 | Myers Scott Dunseth | CASC | Stock Option (Right to buy) | D | 7,08 | -474.810 | 0 | |||||
| 2018-03-13 | 2018-03-09 | 4 | Myers Scott Dunseth | CASC | Common Stock | D | -56.787 | 0 | ||||||
| 2018-03-13 | 2018-03-09 | 4 | SPIEGELMAN DANIEL K | CASC | Restricted Stock Units | D | -13.927 | 0 | ||||||
| 2018-03-13 | 2018-03-09 | 4 | SPIEGELMAN DANIEL K | CASC | Common Stock | D | -21.006 | 0 | ||||||
| 2018-03-13 | 2018-03-09 | 4 | Azelby Robert | CASC | Restricted Stock Units | D | -13.927 | 0 | ||||||
| 2018-03-13 | 2018-03-09 | 4 | Azelby Robert | CASC | Restricted Stock Units | D | -12.437 | 0 | ||||||
| 2018-03-13 | 2018-03-09 | 4 | Florence Anthony A. Jr. See Note 2 | CASC | Common Stock | I | -10.882.574 | 0 | ||||||
| 2018-03-13 | 2018-03-09 | 4 | PETERSON SCOTT ROBERT | CASC | Restricted Stock Units | D | -155.500 | 0 | ||||||
| 2018-03-13 | 2018-03-09 | 4 | PETERSON SCOTT ROBERT | CASC | Restricted Stock Units | D | -14.000 | 0 | ||||||
| 2018-03-13 | 2018-03-09 | 4 | PETERSON SCOTT ROBERT | CASC | Restricted Stock Units | D | -11.300 | 0 | ||||||
| 2018-03-13 | 2018-03-09 | 4 | PETERSON SCOTT ROBERT | CASC | Stock Option (Right to buy) | D | 3,99 | -65.000 | 0 | |||||
| 2018-03-13 | 2018-03-09 | 4 | PETERSON SCOTT ROBERT | CASC | Stock Option (Right to buy) | D | 4,64 | -51.200 | 0 | |||||
| 2018-03-13 | 2018-03-09 | 4 | PETERSON SCOTT ROBERT | CASC | Stock Option (Right to buy) | D | 6,90 | -54.167 | 0 | |||||
| 2018-03-13 | 2018-03-09 | 4 | PETERSON SCOTT ROBERT | CASC | Stock Option (Right to buy) | D | 21,06 | -41.667 | 0 | |||||
| 2018-03-13 | 2018-03-09 | 4 | PETERSON SCOTT ROBERT | CASC | Stock Option (Right to buy) | D | 10,44 | -25.000 | 0 | |||||
| 2018-03-13 | 2018-03-09 | 4 | PETERSON SCOTT ROBERT | CASC | Stock Option (Right to buy) | D | 10,56 | -25.000 | 0 | |||||
| 2018-03-13 | 2018-03-09 | 4 | PETERSON SCOTT ROBERT | CASC | Stock Option (Right to buy) | D | 28,44 | -8.334 | 0 | |||||
| 2018-03-13 | 2018-03-09 | 4 | PETERSON SCOTT ROBERT | CASC | Stock Option (Right to buy) | D | 19,92 | -8.334 | 0 | |||||
| 2018-03-13 | 2018-03-09 | 4 | PETERSON SCOTT ROBERT | CASC | Stock Option (Right to buy) | D | 41,52 | -8.334 | 0 | |||||
| 2018-03-13 | 2018-03-09 | 4 | PETERSON SCOTT ROBERT | CASC | Common Stock | D | -3.639 | 0 | ||||||
| 2018-03-13 | 2018-03-09 | 4 | MAKOWER JOSHUA See Note 2 | CASC | Common Stock | I | -10.882.574 | 0 | ||||||
| 2018-03-13 | 2018-03-09 | 4 | MOTT DAVID M See Note 2 | CASC | Common Stock | I | -10.882.574 | 0 | ||||||
| 2018-03-13 | 2018-03-09 | 4 | Sakoda Jon See Note 2 | CASC | Common Stock | I | -10.882.574 | 0 | ||||||
| 2018-03-13 | 2018-03-09 | 4 | SANDELL SCOTT D See Note 2 | CASC | Common Stock | I | -10.882.574 | 0 | ||||||
| 2018-03-13 | 2018-03-09 | 4 | Sonsini Peter W. See Note 2 | CASC | Common Stock | I | -10.882.574 | 0 | ||||||
| 2018-03-13 | 2018-03-09 | 4 | Viswanathan Ravi See Note 2 | CASC | Common Stock | I | -10.882.574 | 0 | ||||||
| 2018-03-13 | 2018-03-09 | 4 | Fyfe Gwen A. | CASC | Restricted Stock Units | D | -13.927 | 0 | ||||||
| 2018-03-13 | 2018-03-09 | 4 | Fyfe Gwen A. | CASC | Common Stock | D | -10.125 | 0 | ||||||
| 2018-03-13 | 2018-03-09 | 4 | LOVE TED W | CASC | Restricted Stock Units | D | -13.927 | 0 | ||||||
| 2018-03-13 | 2018-03-09 | 4 | LOVE TED W | CASC | Common Stock | D | -37.394 | 0 | ||||||
| 2018-03-13 | 2018-03-09 | 4 | James Steven P | CASC | Restricted Stock Units | D | -13.927 | 0 | ||||||
| 2018-03-13 | 2018-03-09 | 4 | James Steven P | CASC | Common Stock | D | -13.677 | 0 | ||||||
| 2018-03-13 | 2018-03-09 | 4 | Walker Luke Nathaniel | CASC | Restricted Stock Units | D | -130.000 | 0 | ||||||
| 2018-03-13 | 2018-03-09 | 4 | Walker Luke Nathaniel | CASC | Restricted Stock Units | D | -12.000 | 0 | ||||||
| 2018-03-13 | 2018-03-09 | 4 | Walker Luke Nathaniel | CASC | Restricted Stock Units | D | -7.800 | 0 | ||||||
| 2018-03-13 | 2018-03-09 | 4 | Walker Luke Nathaniel | CASC | Stock Option (Right to buy) | D | 3,99 | -50.000 | 0 | |||||
| 2018-03-13 | 2018-03-09 | 4 | Walker Luke Nathaniel | CASC | Stock Option (Right to buy) | D | 4,64 | -35.100 | 0 | |||||
| 2018-03-13 | 2018-03-09 | 4 | Walker Luke Nathaniel | CASC | Stock Option (Right to buy) | D | 6,90 | -20.834 | 0 | |||||
| 2018-03-13 | 2018-03-09 | 4 | Walker Luke Nathaniel | CASC | Stock Option (Right to buy) | D | 6,90 | -8.334 | 0 | |||||
| 2018-03-13 | 2018-03-09 | 4 | Walker Luke Nathaniel | CASC | Stock Option (Right to buy) | D | 21,06 | -5.834 | 0 | |||||
| 2018-03-13 | 2018-03-09 | 4 | Walker Luke Nathaniel | CASC | Stock Option (Right to buy) | D | 28,44 | -1.250 | 0 | |||||
| 2018-03-13 | 2018-03-09 | 4 | Walker Luke Nathaniel | CASC | Stock Option (Right to buy) | D | 10,56 | -1.250 | 0 | |||||
| 2018-03-13 | 2018-03-09 | 4 | Walker Luke Nathaniel | CASC | Stock Option (Right to buy) | D | 35,88 | -2.500 | 0 | |||||
| 2018-03-13 | 2018-03-09 | 4 | Walker Luke Nathaniel | CASC | Stock Option (Right to buy) | D | 10,44 | -2.500 | 0 | |||||
| 2018-03-13 | 2018-03-09 | 4 | Walker Luke Nathaniel | CASC | Stock Option (Right to buy) | D | 41,52 | -334 | 0 | |||||
| 2018-03-13 | 2018-03-09 | 4 | Walker Luke Nathaniel | CASC | Common Stock | D | -10.315 | 0 | ||||||
| 2018-03-13 | 2018-03-09 | 4 | BARRIS PETER J See Note 2 | CASC | Common Stock | I | -10.882.574 | 0 | ||||||
| 2018-02-22 | 2018-02-20 | 4 | Growth Equity Opportunities IV, LLC | CASC | Series E Preferred Stock | D | 3,30 | -1.818.000 | 0 | |||||
| 2018-02-22 | 2018-02-20 | 4 | Growth Equity Opportunities IV, LLC | CASC | Common Stock | D | 3,3000 | 1.818.000 | 5.999 | 10.882.574 | ||||
| 2018-02-22 | 2018-02-20 | 4 | BARRIS PETER J See Note 1 | CASC | Series E Preferred Stock | I | 3,30 | -1.818.000 | 0 | |||||
| 2018-02-22 | 2018-02-20 | 4 | BARRIS PETER J See Note 1 | CASC | Common Stock | I | 3,3000 | 1.818.000 | 5.999 | 10.882.574 | ||||
| 2018-02-22 | 2018-02-20 | 4 | BASKETT FOREST See Note 1 | CASC | Series E Preferred Stock | I | 3,30 | -1.818.000 | 0 | |||||
| 2018-02-22 | 2018-02-20 | 4 | BASKETT FOREST See Note 1 | CASC | Common Stock | I | 3,3000 | 1.818.000 | 5.999 | 10.882.574 | ||||
| 2018-02-22 | 2018-02-20 | 4 | Florence Anthony A. Jr. See Note 1 | CASC | Series E Preferred Stock | I | 3,30 | -1.818.000 | 0 | |||||
| 2018-02-22 | 2018-02-20 | 4 | Florence Anthony A. Jr. See Note 1 | CASC | Common Stock | I | 3,3000 | 1.818.000 | 5.999 | 10.882.574 | ||||
| 2018-02-22 | 2018-02-20 | 4 | MAKOWER JOSHUA See Note 1 | CASC | Series E Preferred Stock | I | 3,30 | -1.818.000 | 0 | |||||
| 2018-02-22 | 2018-02-20 | 4 | MAKOWER JOSHUA See Note 1 | CASC | Common Stock | I | 3,3000 | 1.818.000 | 5.999 | 10.882.574 | ||||
| 2018-02-22 | 2018-02-20 | 4 | MOTT DAVID M See Note 1 | CASC | Series E Preferred Stock | I | 3,30 | -1.818.000 | 0 | |||||
| 2018-02-22 | 2018-02-20 | 4 | MOTT DAVID M See Note 1 | CASC | Common Stock | I | 3,3000 | 1.818.000 | 5.999 | 10.882.574 | ||||
| 2018-02-22 | 2018-02-20 | 4 | Sakoda Jon See Note 1 | CASC | Series E Preferred Stock | I | 3,30 | -1.818.000 | 0 | |||||
| 2018-02-22 | 2018-02-20 | 4 | Sakoda Jon See Note 1 | CASC | Common Stock | I | 3,3000 | 1.818.000 | 5.999 | 10.882.574 | ||||
| 2018-02-22 | 2018-02-20 | 4 | SANDELL SCOTT D See Note 1 | CASC | Series E Preferred Stock | I | 3,30 | -1.818.000 | 0 | |||||
| 2018-02-22 | 2018-02-20 | 4 | SANDELL SCOTT D See Note 1 | CASC | Common Stock | I | 3,3000 | 1.818.000 | 5.999 | 10.882.574 | ||||
| 2018-02-22 | 2018-02-20 | 4 | Sonsini Peter W. See Note 1 | CASC | Series E Preferred Stock | I | 3,30 | -1.818.000 | 0 | |||||
| 2018-02-22 | 2018-02-20 | 4 | Sonsini Peter W. See Note 1 | CASC | Common Stock | I | 3,3000 | 1.818.000 | 5.999 | 10.882.574 | ||||
| 2018-02-22 | 2018-02-20 | 4 | Viswanathan Ravi See Note 1 | CASC | Series E Preferred Stock | I | 3,30 | -1.818.000 | 0 | |||||
| 2018-02-22 | 2018-02-20 | 4 | Viswanathan Ravi See Note 1 | CASC | Common Stock | I | 3,3000 | 1.818.000 | 5.999 | 10.882.574 | ||||
| 2018-02-02 | 2018-02-01 | 4 | Christianson Gary | CASC | Restricted Share Unit (RSU) | D | 164.500 | 164.500 | ||||||
| 2018-02-02 | 2018-02-01 | 4 | EASTLAND JULIA MARIE | CASC | Restricted Share Unit (RSU) | D | 199.000 | 199.000 | ||||||
| 2018-02-02 | 2018-02-01 | 4 | Myers Scott Dunseth | CASC | Restricted Share Unit (RSU) | D | 250.000 | 250.000 | ||||||
| 2018-02-02 | 2018-02-01 | 4 | PETERSON SCOTT ROBERT | CASC | Restricted Share Unit (RSU) | D | 155.500 | 155.500 | ||||||
| 2018-02-02 | 2018-02-01 | 4 | Walker Luke Nathaniel | CASC | Restricted Share Unit (RSU) | D | 130.000 | 130.000 | ||||||
| 2018-01-16 | 2018-01-11 | 4 | Christianson Gary | CASC | Restricted Share Unit (RSU) | D | -2.825 | 8.475 | ||||||
| 2018-01-16 | 2018-01-11 | 4 | Christianson Gary | CASC | Common Stock | D | 3,9200 | -923 | -4 | 6.515 | ||||
| 2018-01-16 | 2018-01-11 | 4 | Christianson Gary | CASC | Common Stock | D | 2.825 | 7.438 | ||||||
| 2018-01-16 | 2018-01-11 | 4 | EASTLAND JULIA MARIE | CASC | Restricted Share Unit (RSU) | D | -2.825 | 8.475 | ||||||
| 2018-01-16 | 2018-01-11 | 4 | EASTLAND JULIA MARIE | CASC | Common Stock | D | 3,9200 | -923 | -4 | 5.237 | ||||
| 2018-01-16 | 2018-01-11 | 4 | EASTLAND JULIA MARIE | CASC | Common Stock | D | 2.825 | 6.160 | ||||||
| 2018-01-16 | 2018-01-11 | 4 | Myers Scott Dunseth | CASC | Restricted Share Unit (RSU) | D | -10.500 | 31.500 | ||||||
| 2018-01-16 | 2018-01-11 | 4 | Myers Scott Dunseth | CASC | Common Stock | D | 3,9200 | -3.429 | -13 | 56.787 | ||||
| 2018-01-16 | 2018-01-11 | 4 | Myers Scott Dunseth | CASC | Common Stock | D | 10.500 | 60.216 | ||||||
| 2018-01-16 | 2018-01-11 | 4 | PETERSON SCOTT ROBERT | CASC | Restricted Share Unit (RSU) | D | -2.825 | 8.475 | ||||||
| 2018-01-16 | 2018-01-11 | 4 | PETERSON SCOTT ROBERT | CASC | Common Stock | D | 3,9200 | -923 | -4 | 3.639 | ||||
| 2018-01-16 | 2018-01-11 | 4 | PETERSON SCOTT ROBERT | CASC | Common Stock | D | 2.825 | 4.562 | ||||||
| 2018-01-16 | 2018-01-11 | 4 | Walker Luke Nathaniel | CASC | Restricted Share Unit (RSU) | D | -1.950 | 5.850 | ||||||
| 2018-01-16 | 2018-01-11 | 4 | Walker Luke Nathaniel | CASC | Common Stock | D | 3,9200 | -637 | -2 | 5.303 | ||||
| 2018-01-16 | 2018-01-11 | 4 | Walker Luke Nathaniel | CASC | Common Stock | D | 1.950 | 5.940 | ||||||
| 2017-11-13 | 2017-11-10 | 4 | Myers Scott Dunseth | CASC | Restricted Share Unit (RSU) | D | 6.300 | 6.300 | ||||||
| 2017-09-26 | 2017-09-24 | 4 | HENNEY CHRISTOPHER S | CASC | Restricted Share Unit (RSU) | D | -2.375 | 0 | ||||||
| 2017-09-26 | 2017-09-24 | 4 | HENNEY CHRISTOPHER S | CASC | Common Stock | D | 3,9400 | -594 | -2 | 60.185 | ||||
| 2017-09-26 | 2017-09-24 | 4 | HENNEY CHRISTOPHER S | CASC | Common Stock | D | 2.375 | 60.779 | ||||||
| 2017-09-26 | 2017-09-24 | 4 | James Steven P | CASC | Restricted Share Unit (RSU) | D | -2.375 | 0 | ||||||
| 2017-09-26 | 2017-09-24 | 4 | James Steven P | CASC | Common Stock | D | 3,9400 | -594 | -2 | 13.677 | ||||
| 2017-09-26 | 2017-09-24 | 4 | James Steven P | CASC | Common Stock | D | 2.375 | 14.271 | ||||||
| 2017-09-26 | 2017-09-24 | 4 | LOVE TED W | CASC | Restricted Share Unit (RSU) | D | -2.375 | 0 | ||||||
| 2017-09-26 | 2017-09-24 | 4 | LOVE TED W | CASC | Common Stock | D | 3,9400 | -594 | -2 | 37.394 | ||||
| 2017-09-26 | 2017-09-24 | 4 | LOVE TED W | CASC | Common Stock | D | 2.375 | 37.988 | ||||||
| 2017-09-26 | 2017-09-24 | 4 | SPIEGELMAN DANIEL K | CASC | Restricted Share Unit (RSU) | D | -2.375 | 0 | ||||||
| 2017-09-26 | 2017-09-24 | 4 | SPIEGELMAN DANIEL K | CASC | Common Stock | D | 3,9400 | -594 | -2 | 21.006 | ||||
| 2017-09-26 | 2017-09-24 | 4 | SPIEGELMAN DANIEL K | CASC | Common Stock | D | 2.375 | 21.600 | ||||||
| 2017-09-20 | 2017-09-18 | 4 | Myers Scott Dunseth | CASC | Restricted Share Unit (RSU) | D | 15.500 | 15.500 | ||||||
| 2017-09-20 | 2017-09-18 | 4 | Myers Scott Dunseth | CASC | Stock Option (right to buy) | D | 3,99 | 60.000 | 60.000 | |||||
| 2017-09-20 | 2017-09-18 | 4 | Christianson Gary | CASC | Restricted Share Unit (RSU) | D | 15.000 | 15.000 | ||||||
| 2017-09-20 | 2017-09-18 | 4 | Christianson Gary | CASC | Stock Option (right to buy) | D | 3,99 | 68.000 | 68.000 | |||||
| 2017-09-20 | 2017-09-18 | 4 | EASTLAND JULIA MARIE | CASC | Restricted Share Unit (RSU) | D | 16.500 | 16.500 | ||||||
| 2017-09-20 | 2017-09-18 | 4 | EASTLAND JULIA MARIE | CASC | Stock Option (right to buy) | D | 3,99 | 75.000 | 75.000 | |||||
| 2017-09-20 | 2017-09-18 | 4 | Walker Luke Nathaniel | CASC | Restricted Share Unit (RSU) | D | 12.000 | 12.000 | ||||||
| 2017-09-20 | 2017-09-18 | 4 | Walker Luke Nathaniel | CASC | Stock Option (right to buy) | D | 3,99 | 50.000 | 50.000 | |||||
| 2017-09-20 | 2017-09-18 | 4 | PETERSON SCOTT ROBERT | CASC | Restricted Share Unit (RSU) | D | 14.000 | 14.000 | ||||||
| 2017-09-20 | 2017-09-18 | 4 | PETERSON SCOTT ROBERT | CASC | Stock Option (right to buy) | D | 3,99 | 65.000 | 65.000 | |||||
| 2017-08-14 | 2017-08-11 | 4 | Myers Scott Dunseth | CASC | Common Stock | D | 3,7350 | 5.500 | 21 | 49.716 | ||||
| 2017-06-27 | 2017-06-24 | 4 | SPIEGELMAN DANIEL K | CASC | Restricted Share Unit (RSU) | D | -9.058 | 0 | ||||||
| 2017-06-27 | 2017-06-24 | 4 | SPIEGELMAN DANIEL K | CASC | Common Stock | D | 3,7800 | -2.265 | -9 | 19.225 | ||||
| 2017-06-27 | 2017-06-24 | 4 | SPIEGELMAN DANIEL K | CASC | Common Stock | D | 9.058 | 21.490 | ||||||
| 2017-06-27 | 2017-06-24 | 4 | Fyfe Gwen A. | CASC | Restricted Share Unit (RSU) | D | -9.058 | 0 | ||||||
| 2017-06-27 | 2017-06-24 | 4 | Fyfe Gwen A. | CASC | Common Stock | D | 3,7800 | -2.265 | -9 | 10.125 | ||||
| 2017-06-27 | 2017-06-24 | 4 | Fyfe Gwen A. | CASC | Common Stock | D | 9.058 | 12.390 | ||||||
| 2017-06-27 | 2017-06-24 | 4 | HENNEY CHRISTOPHER S | CASC | Restricted Share Unit (RSU) | D | -9.058 | 0 | ||||||
| 2017-06-27 | 2017-06-24 | 4 | HENNEY CHRISTOPHER S | CASC | Common Stock | D | 3,7800 | -2.265 | -9 | 58.404 | ||||
| 2017-06-27 | 2017-06-24 | 4 | HENNEY CHRISTOPHER S | CASC | Common Stock | D | 9.058 | 60.669 | ||||||
| 2017-06-27 | 2017-06-24 | 4 | James Steven P | CASC | Restricted Share Unit (RSU) | D | -9.058 | 0 | ||||||
| 2017-06-27 | 2017-06-24 | 4 | James Steven P | CASC | Common Stock | D | 3,7800 | -2.265 | -9 | 11.896 | ||||
| 2017-06-27 | 2017-06-24 | 4 | James Steven P | CASC | Common Stock | D | 9.058 | 14.161 | ||||||
| 2017-06-27 | 2017-06-24 | 4 | LOVE TED W | CASC | Restricted Share Unit (RSU) | D | -9.058 | 0 | ||||||
| 2017-06-27 | 2017-06-24 | 4 | LOVE TED W | CASC | Common Stock | D | 3,7800 | -2.265 | -9 | 35.613 | ||||
| 2017-06-27 | 2017-06-24 | 4 | LOVE TED W | CASC | Common Stock | D | 9.058 | 37.878 | ||||||
| 2017-06-13 | 2017-06-09 | 4 | Fyfe Gwen A. | CASC | Restricted Share Unit (RSU) | D | 13.927 | 13.927 | ||||||
| 2017-06-13 | 2017-06-12 | 4 | HENNEY CHRISTOPHER S | CASC | Restricted Share Unit (RSU) | D | -2.148 | 0 | ||||||
| 2017-06-13 | 2017-06-12 | 4 | HENNEY CHRISTOPHER S | CASC | Common Stock | D | 3,3400 | -537 | -2 | 51.611 | ||||
| 2017-06-13 | 2017-06-12 | 4 | HENNEY CHRISTOPHER S | CASC | Common Stock | D | 2.148 | 52.148 | ||||||
| 2017-06-13 | 2017-06-09 | 4 | HENNEY CHRISTOPHER S | CASC | Restricted Share Unit (RSU) | D | 13.927 | 13.927 | ||||||
| 2017-06-13 | 2017-06-12 | 4 | James Steven P | CASC | Restricted Share Unit (RSU) | D | -2.148 | 0 | ||||||
| 2017-06-13 | 2017-06-12 | 4 | James Steven P | CASC | Common Stock | D | 3,3400 | -537 | -2 | 5.103 | ||||
| 2017-06-13 | 2017-06-12 | 4 | James Steven P | CASC | Common Stock | D | 2.148 | 5.640 | ||||||
| 2017-06-13 | 2017-06-09 | 4 | James Steven P | CASC | Restricted Share Unit (RSU) | D | 13.927 | 13.927 | ||||||
| 2017-06-13 | 2017-06-12 | 4 | LOVE TED W | CASC | Restricted Share Unit (RSU) | D | -2.148 | 0 | ||||||
| 2017-06-13 | 2017-06-12 | 4 | LOVE TED W | CASC | Common Stock | D | 3,3400 | -537 | -2 | 28.820 | ||||
| 2017-06-13 | 2017-06-12 | 4 | LOVE TED W | CASC | Common Stock | D | 2.148 | 29.357 | ||||||
| 2017-06-13 | 2017-06-09 | 4 | LOVE TED W | CASC | Restricted Share Unit (RSU) | D | 13.927 | 13.927 | ||||||
| 2017-06-13 | 2017-06-12 | 4 | SPIEGELMAN DANIEL K | CASC | Restricted Share Unit (RSU) | D | -2.148 | 0 | ||||||
| 2017-06-13 | 2017-06-12 | 4 | SPIEGELMAN DANIEL K | CASC | Common Stock | D | 3,3400 | -537 | -2 | 12.432 | ||||
| 2017-06-13 | 2017-06-12 | 4 | SPIEGELMAN DANIEL K | CASC | Common Stock | D | 2.148 | 12.969 | ||||||
| 2017-06-13 | 2017-06-09 | 4 | SPIEGELMAN DANIEL K | CASC | Restricted Share Unit (RSU) | D | 13.927 | 13.927 | ||||||
| 2017-06-13 | 2017-06-09 | 4 | Azelby Robert | CASC | Restricted Share Unit (RSU) | D | 13.927 | 13.927 | ||||||
| 2017-05-16 | 2017-05-12 | 4 | Myers Scott Dunseth | CASC | Common Stock | D | 3,9970 | 2.800 | 11 | 44.216 | ||||
| 2017-04-04 | 3 | Azelby Robert | CASC | No securities were benefically held | D | 0 | ||||||||
| 2017-04-04 | 2017-04-03 | 4 | Azelby Robert | CASC | Restricted Stock Unit (RSU) | D | 12.437 | 12.437 | ||||||
| 2017-04-04 | 2017-03-31 | 4 | Myers Scott Dunseth | CASC | Common Stock | D | 4,1143 | 2.000 | 8 | 41.416 | ||||
| 2017-03-30 | 2017-03-28 | 4 | Fyfe Gwen A. | CASC | Common Stock | D | 4,1158 | 1.666 | 7 | 3.332 | ||||
| 2017-03-21 | 2017-03-20 | 4 | Myers Scott Dunseth | CASC | Common Stock | D | 3,9271 | 1.000 | 4 | 39.416 | ||||
| 2017-03-20 | 3 | Walker Luke Nathaniel | CASC | Common Stock | D | 7.980 | ||||||||
| 2017-03-20 | 3 | Walker Luke Nathaniel | CASC | Common Stock | D | 7.980 | ||||||||
| 2017-03-14 | 2017-03-12 | 4 | James Steven P | CASC | Restricted Share Unit (RSU) | D | -4.656 | 0 | ||||||
| 2017-03-14 | 2017-03-12 | 4 | James Steven P | CASC | Common Stock | D | 4,3500 | -1.164 | -5 | 3.492 | ||||
| 2017-03-14 | 2017-03-12 | 4 | James Steven P | CASC | Common Stock | D | 4.656 | 4.656 | ||||||
| 2017-02-10 | 2016-06-06 | 5 | HENNEY CHRISTOPHER S | CASC | Restricted Share Unit (RSU) | D | -2.723 | 0 | ||||||
| 2017-02-10 | 2016-06-06 | 5 | HENNEY CHRISTOPHER S | CASC | Common Stock | D | 7,3800 | -681 | -5 | 50.000 | ||||
| 2017-02-10 | 2016-06-06 | 5 | HENNEY CHRISTOPHER S | CASC | Common Stock | D | 2.723 | 50.861 | ||||||
| 2017-02-10 | 2016-06-06 | 5 | Jackson Richard L. | CASC | Restricted Share Unit (RSU) | D | -2.723 | 0 | ||||||
| 2017-02-10 | 2016-06-06 | 5 | Jackson Richard L. | CASC | Common Stock | D | 7,3800 | -681 | -5 | 11.968 | ||||
| 2017-02-10 | 2016-06-06 | 5 | Jackson Richard L. | CASC | Common Stock | D | 2.723 | 12.649 | ||||||
| 2017-02-10 | 2016-06-06 | 5 | LOVE TED W | CASC | Restricted Share Unit (RSU) | D | -2.723 | 0 | ||||||
| 2017-02-10 | 2016-06-06 | 5 | LOVE TED W | CASC | Common Stock | D | 7,3800 | -681 | -5 | 27.209 | ||||
| 2017-02-10 | 2016-06-06 | 5 | LOVE TED W | CASC | Common Stock | D | 2.723 | 27.890 | ||||||
| 2017-02-10 | 2016-06-06 | 5 | SPIEGELMAN DANIEL K | CASC | Restricted Share Unit (RSU) | D | -2.723 | 0 | ||||||
| 2017-02-10 | 2016-06-06 | 5 | SPIEGELMAN DANIEL K | CASC | Common Stock | D | 7,3800 | -681 | -5 | 10.821 | ||||
| 2017-02-10 | 2016-06-06 | 5 | SPIEGELMAN DANIEL K | CASC | Common Stock | D | 2.723 | 11.502 | ||||||
| 2017-02-03 | 2017-02-02 | 4 | LOVE TED W | CASC | Common Stock | D | 4,2400 | 23.000 | 98 | 27.209 | ||||
| 2017-02-01 | 3 | BARRIS PETER J See Note 1 | CASC | Common Stock | I | 18.129.148 | ||||||||
| 2017-02-01 | 3 | BARRIS PETER J See Note 1 | CASC | Common Stock | I | 18.129.148 | ||||||||
| 2017-02-01 | 3 | BASKETT FOREST See Note 1 | CASC | Common Stock | I | 18.129.148 | ||||||||
| 2017-02-01 | 3 | BASKETT FOREST See Note 1 | CASC | Common Stock | I | 18.129.148 | ||||||||
| 2017-02-01 | 3 | SANDELL SCOTT D See Note 1 | CASC | Common Stock | I | 18.129.148 | ||||||||
| 2017-02-01 | 3 | SANDELL SCOTT D See Note 1 | CASC | Common Stock | I | 18.129.148 | ||||||||
| 2017-02-01 | 3 | MOTT DAVID M See Note 1 | CASC | Common Stock | I | 18.129.148 | ||||||||
| 2017-02-01 | 3 | MOTT DAVID M See Note 1 | CASC | Common Stock | I | 18.129.148 | ||||||||
| 2017-02-01 | 3 | MAKOWER JOSHUA See Note 1 | CASC | Common Stock | I | 18.129.148 | ||||||||
| 2017-02-01 | 3 | MAKOWER JOSHUA See Note 1 | CASC | Common Stock | I | 18.129.148 | ||||||||
| 2017-02-01 | 3 | Viswanathan Ravi See Note 1 | CASC | Common Stock | I | 18.129.148 | ||||||||
| 2017-02-01 | 3 | Viswanathan Ravi See Note 1 | CASC | Common Stock | I | 18.129.148 | ||||||||
| 2017-02-01 | 3 | Sonsini Peter W. See Note 1 | CASC | Common Stock | I | 18.129.148 | ||||||||
| 2017-02-01 | 3 | Sonsini Peter W. See Note 1 | CASC | Common Stock | I | 18.129.148 | ||||||||
| 2017-02-01 | 3 | Sakoda Jon See Note 1 | CASC | Common Stock | I | 18.129.148 | ||||||||
| 2017-02-01 | 3 | Sakoda Jon See Note 1 | CASC | Common Stock | I | 18.129.148 | ||||||||
| 2017-02-01 | 3 | Florence Anthony A. Jr. See Note 1 | CASC | Common Stock | I | 18.129.148 | ||||||||
| 2017-02-01 | 3 | Florence Anthony A. Jr. See Note 1 | CASC | Common Stock | I | 18.129.148 | ||||||||
| 2017-02-01 | 3 | New Enterprise Associates 15, L.P. | CASC | Common Stock | D | 18.129.148 | ||||||||
| 2017-02-01 | 3 | New Enterprise Associates 15, L.P. | CASC | Common Stock | D | 18.129.148 | ||||||||
| 2017-02-01 | 3 | New Enterprise Associates 15, L.P. | CASC | Common Stock | D | 18.129.148 | ||||||||
| 2017-02-01 | 3 | New Enterprise Associates 15, L.P. | CASC | Common Stock | D | 18.129.148 | ||||||||
| 2017-02-01 | 3 | New Enterprise Associates 15, L.P. | CASC | Common Stock | D | 18.129.148 | ||||||||
| 2017-02-01 | 2017-01-30 | 4 | HENNEY CHRISTOPHER S | CASC | Common Stock | D | 4,1057 | 25.324 | 104 | 50.000 | ||||
| 2017-01-31 | 2017-01-27 | 4 | Myers Scott Dunseth | CASC | Common Stock | D | 3,7580 | 20.500 | 77 | 38.416 | ||||
| 2017-01-13 | 2017-01-11 | 4 | Myers Scott Dunseth | CASC | Restricted Share Unit (RSU) | D | 42.000 | 42.000 | ||||||
| 2017-01-13 | 2017-01-11 | 4 | Myers Scott Dunseth | CASC | Stock Option (right to buy) | D | 4,64 | 190.000 | 190.000 | |||||
| 2017-01-13 | 2017-01-11 | 4 | Christianson Gary | CASC | Restricted Share Unit (RSU) | D | 11.300 | 11.300 | ||||||
| 2017-01-13 | 2017-01-11 | 4 | Christianson Gary | CASC | Stock Option (right to buy) | D | 4,64 | 51.200 | 51.200 | |||||
| 2017-01-13 | 2017-01-11 | 4 | EASTLAND JULIA MARIE | CASC | Restricted Share Unit (RSU) | D | 11.300 | 11.300 | ||||||
| 2017-01-13 | 2017-01-11 | 4 | EASTLAND JULIA MARIE | CASC | Stock Option (right to buy) | D | 4,64 | 51.200 | 51.200 | |||||
| 2017-01-13 | 2017-01-11 | 4 | PETERSON SCOTT ROBERT | CASC | Restricted Share Unit (RSU) | D | 11.300 | 11.300 | ||||||
| 2017-01-13 | 2017-01-11 | 4 | PETERSON SCOTT ROBERT | CASC | Stock Option (right to buy) | D | 4,64 | 51.200 | 51.200 | |||||
| 2016-08-18 | 2016-08-17 | 4 | Myers Scott Dunseth | CASC | Common Stock | D | 1,1499 | 45.000 | 52 | 107.500 | ||||
| 2016-06-28 | 2016-06-24 | 4 | HENNEY CHRISTOPHER S | CASC | Restricted Share Units (RSU) | D | 54.347 | 54.347 | ||||||
| 2016-06-28 | 2016-06-24 | 4 | James Steven P | CASC | Restricted Share Unit (RSU) | D | 54.347 | 54.347 | ||||||
| 2016-06-28 | 2016-06-24 | 4 | LOVE TED W | CASC | Restricted Share Unit (RSU) | D | 54.347 | 54.347 | ||||||
| 2016-06-28 | 2016-06-24 | 4 | SPIEGELMAN DANIEL K | CASC | Restricted Share Unit (RSU) | D | 54.347 | 54.347 | ||||||
| 2016-06-28 | 2016-06-28 | 4 | Myers Scott Dunseth | CASC | Common Stock | D | 0,8000 | 62.500 | 50 | 62.500 | ||||
| 2016-06-28 | 2016-06-24 | 4 | Jackson Richard L. | CASC | Restricted Share Unit (RSU) | D | 54.347 | 54.347 | ||||||
| 2016-06-28 | 2016-06-24 | 4 | Fyfe Gwen A. | CASC | Restricted Share Unit (RSU) | D | 54.347 | 54.347 | ||||||
| 2016-06-27 | 2016-06-23 | 4 | LAMPERT MARK N Please see footnote | ONTY | Series D Convertible Preferred Stock | I | 0,80 | 800,0000 | 6.197 | 4.958 | 6.197 | |||
| 2016-06-27 | 2016-06-23 | 4 | LAMPERT MARK N | ONTY | Series D Convertible Preferred Stock | D | 0,80 | 800,0000 | 1.029 | 823 | 1.029 | |||
| 2016-06-27 | 2016-06-23 | 4 | LAMPERT MARK N | ONTY | Series D Convertible Preferred Stock | D | 0,80 | 800,0000 | 4.519 | 3.615 | 4.519 | |||
| 2016-06-27 | 2016-06-23 | 4 | LAMPERT MARK N | ONTY | Series D Convertible Preferred Stock | D | 0,80 | 800,0000 | 5.505 | 4.404 | 5.505 | |||
| 2016-05-19 | 2016-05-17 | 4 | Christianson Gary | ONTY | Stock Option (right to buy) | D | 1,15 | 250.000 | 250.000 | |||||
| 2016-05-19 | 2016-05-17 | 4 | EASTLAND JULIA MARIE | ONTY | Stock Option (right to buy) | D | 1,15 | 300.000 | 300.000 | |||||
| 2016-05-19 | 2016-05-17 | 4 | PETERSON SCOTT ROBERT | ONTY | Stock Option (right to buy) | D | 1,15 | 325.000 | 325.000 | |||||
| 2016-04-06 | 3 | Myers Scott Dunseth | ONTY | No securities beneficially held | D | 0 | ||||||||
| 2016-04-06 | 2016-04-04 | 4 | Myers Scott Dunseth | ONTY | Stock Option (right to buy) | D | 1,18 | 2.848.855 | 2.848.855 | |||||
| 2016-03-16 | 2016-03-16 | 4 | HENNEY CHRISTOPHER S | ONTY | Stock Option (right to buy) | D | 1,06 | 150.000 | 150.000 | |||||
| 2016-01-21 | 3 | Fyfe Gwen A. | ONTY | Common Stock | D | 20.000 | ||||||||
| 2016-01-21 | 3 | Fyfe Gwen A. | ONTY | Common Stock | D | 20.000 | ||||||||
| 2015-12-22 | 3 | LAMPERT MARK N | ONTY | Common Stock, no par value per share | D | 23.547.788 | ||||||||
| 2015-12-22 | 3 | LAMPERT MARK N | ONTY | Common Stock, no par value per share | D | 21.842.395 | ||||||||
| 2015-12-22 | 3 | LAMPERT MARK N | ONTY | Common Stock, no par value per share | D | 23.547.788 | ||||||||
| 2015-12-22 | 3 | LAMPERT MARK N | ONTY | Common Stock, no par value per share | D | 23.547.788 | ||||||||
| 2015-12-22 | 3 | LAMPERT MARK N | ONTY | Common Stock, no par value per share | D | 21.842.395 | ||||||||
| 2015-12-22 | 3 | LAMPERT MARK N | ONTY | Common Stock, no par value per share | D | 19.541.857 | ||||||||
| 2015-12-22 | 3 | LAMPERT MARK N Please see footnote | ONTY | Common Stock, no par value per share | I | 29.064.800 | ||||||||
| 2015-12-22 | 3 | LAMPERT MARK N | ONTY | Common Stock, no par value per share | D | 23.547.788 | ||||||||
| 2015-12-22 | 3 | LAMPERT MARK N | ONTY | Common Stock, no par value per share | D | 21.842.395 | ||||||||
| 2015-12-22 | 3 | LAMPERT MARK N | ONTY | Common Stock, no par value per share | D | 19.541.857 | ||||||||
| 2015-12-22 | 3 | LAMPERT MARK N Please see footnote | ONTY | Common Stock, no par value per share | I | 29.064.800 | ||||||||
| 2015-12-22 | 3 | LAMPERT MARK N | ONTY | Common Stock, no par value per share | D | 23.547.788 | ||||||||
| 2015-12-22 | 3 | LAMPERT MARK N | ONTY | Common Stock, no par value per share | D | 19.541.857 | ||||||||
| 2015-12-22 | 3 | LAMPERT MARK N | ONTY | Common Stock, no par value per share | D | 21.842.395 | ||||||||
| 2015-12-22 | 3 | LAMPERT MARK N | ONTY | Common Stock, no par value per share | D | 19.541.857 | ||||||||
| 2015-12-22 | 3 | LAMPERT MARK N Please see footnote | ONTY | Common Stock, no par value per share | I | 29.064.800 | ||||||||
| 2015-12-22 | 3 | LAMPERT MARK N | ONTY | Common Stock, no par value per share | D | 21.842.395 | ||||||||
| 2015-12-22 | 3 | LAMPERT MARK N Please see footnote | ONTY | Common Stock, no par value per share | I | 29.064.800 | ||||||||
| 2015-12-22 | 3 | LAMPERT MARK N | ONTY | Common Stock, no par value per share | D | 19.541.857 | ||||||||
| 2015-12-22 | 3 | LAMPERT MARK N Please see footnote | ONTY | Common Stock, no par value per share | I | 29.064.800 | ||||||||
| 2015-12-22 | 3 | LAMPERT MARK N | ONTY | Common Stock, no par value per share | D | 21.842.395 | ||||||||
| 2015-12-22 | 3 | LAMPERT MARK N | ONTY | Common Stock, no par value per share | D | 23.547.788 | ||||||||
| 2015-12-22 | 3 | LAMPERT MARK N | ONTY | Common Stock, no par value per share | D | 19.541.857 | ||||||||
| 2015-12-22 | 3 | LAMPERT MARK N Please see footnote | ONTY | Common Stock, no par value per share | I | 29.064.800 | ||||||||
| 2015-12-22 | 3 | LAMPERT MARK N | ONTY | Common Stock, no par value per share | D | 23.547.788 | ||||||||
| 2015-12-22 | 3 | LAMPERT MARK N | ONTY | Common Stock, no par value per share | D | 21.842.395 | ||||||||
| 2015-12-22 | 3 | LAMPERT MARK N | ONTY | Common Stock, no par value per share | D | 19.541.857 | ||||||||
| 2015-12-22 | 3 | LAMPERT MARK N Please see footnote | ONTY | Common Stock, no par value per share | I | 29.064.800 | ||||||||
| 2015-12-22 | 3 | LAMPERT MARK N | ONTY | Common Stock, no par value per share | D | 23.547.788 | ||||||||
| 2015-12-22 | 3 | LAMPERT MARK N | ONTY | Common Stock, no par value per share | D | 21.842.395 | ||||||||
| 2015-12-22 | 3 | LAMPERT MARK N | ONTY | Common Stock, no par value per share | D | 19.541.857 | ||||||||
| 2015-12-22 | 3 | LAMPERT MARK N Please see footnote | ONTY | Common Stock, no par value per share | I | 29.064.800 | ||||||||
| 2015-09-28 | 2015-09-24 | 4 | PETERSON SCOTT ROBERT | ONTY | Stock Option (right to buy) | D | 3,51 | 250.000 | 250.000 | |||||
| 2015-09-28 | 2015-09-24 | 4 | Jackson Richard L. | ONTY | Restricted Share Unit (RSU) | D | 14.245 | 14.245 | ||||||
| 2015-09-28 | 2015-09-24 | 4 | HAUSMAN DIANA | ONTY | Stock Option (right to buy) | D | 3,51 | 250.000 | 250.000 | |||||
| 2015-09-28 | 2015-09-24 | 4 | LOVE TED W | ONTY | Restricted Share Unit (RSU) | D | 14.245 | 14.245 | ||||||
| 2015-09-28 | 2015-09-24 | 4 | James Steven P | ONTY | Restricted Share Unit (RSU) | D | 14.245 | 14.245 | ||||||
| 2015-09-28 | 2015-09-24 | 4 | HENNEY CHRISTOPHER S | ONTY | Restricted Share Units (RSU) | D | 14.245 | 14.245 | ||||||
| 2015-09-28 | 2015-09-24 | 4 | KIRKMAN ROBERT L | ONTY | Stock Option (right to buy) | D | 3,51 | 750.000 | 750.000 | |||||
| 2015-09-28 | 2015-09-24 | 4 | SPIEGELMAN DANIEL K | ONTY | Restricted Share Unit (RSU) | D | 14.245 | 14.245 | ||||||
| 2015-09-28 | 2015-09-24 | 4 | EASTLAND JULIA MARIE | ONTY | Stock Option (right to buy) | D | 3,51 | 250.000 | 250.000 | |||||
| 2015-09-28 | 2015-09-24 | 4 | Christianson Gary | ONTY | Stock Option (right to buy) | D | 3,51 | 250.000 | 250.000 | |||||
| 2015-09-09 | 2015-09-05 | 4 | LOVE TED W | ONTY | Restricted Share Unit (RSU) | D | -17.341 | 0 | ||||||
| 2015-09-09 | 2015-09-05 | 4 | LOVE TED W | ONTY | Common Stock | D | 3,2500 | -4.336 | -14 | 13.005 | ||||
| 2015-09-09 | 2015-09-05 | 4 | LOVE TED W | ONTY | Common Stock | D | 17.341 | 17.341 | ||||||
| 2015-06-16 | 2015-06-13 | 4 | HENNEY CHRISTOPHER S | ONTY | Restricted Share Unit (RSU) | D | -16.042 | 0 | ||||||
| 2015-06-16 | 2014-06-13 | 4 | HENNEY CHRISTOPHER S | ONTY | Common Stock | D | 3,8800 | -4.011 | -16 | 135.807 | ||||
| 2015-06-16 | 2014-06-13 | 4 | HENNEY CHRISTOPHER S | ONTY | Common Stock | D | 16.042 | 139.818 | ||||||
| 2015-06-16 | 2014-06-12 | 4 | HENNEY CHRISTOPHER S | ONTY | Restricted Share Units (RSU) | D | 12.886 | 12.886 | ||||||
| 2015-06-16 | 2015-06-12 | 4 | James Steven P | ONTY | Restricted Share Unit (RSU) | D | 12.886 | 12.886 | ||||||
| 2015-06-16 | 2015-06-12 | 4 | LOVE TED W | ONTY | Restricted Share Unit (RSU) | D | 12.886 | 12.886 | ||||||
| 2015-06-16 | 2015-06-13 | 4 | SPIEGELMAN DANIEL K | ONTY | Restricted Share Unit (RSU) | D | -16.042 | 0 | ||||||
| 2015-06-16 | 2015-06-13 | 4 | SPIEGELMAN DANIEL K | ONTY | Common Stock | D | 3,8800 | -4.011 | -16 | 52.675 | ||||
| 2015-06-16 | 2015-06-13 | 4 | SPIEGELMAN DANIEL K | ONTY | Common Stock | D | 16.042 | 56.686 | ||||||
| 2015-06-16 | 2015-06-12 | 4 | SPIEGELMAN DANIEL K | ONTY | Restricted Share Unit (RSU) | D | 12.886 | 12.886 | ||||||
| 2015-06-16 | 2015-06-13 | 4 | Jackson Richard L. | ONTY | Restricted Share Unit (RSU) | D | -16.042 | 0 | ||||||
| 2015-06-16 | 2015-06-13 | 4 | Jackson Richard L. | ONTY | Common Stock | D | 3,8800 | -4.011 | -16 | 59.557 | ||||
| 2015-06-16 | 2015-06-13 | 4 | Jackson Richard L. | ONTY | Common Stock | D | 16.042 | 63.568 | ||||||
| 2015-06-16 | 2015-06-12 | 4 | Jackson Richard L. | ONTY | Restricted Share Unit (RSU) | D | 12.886 | 12.886 | ||||||
| 2015-06-03 | 2015-06-01 | 4 | HAUSMAN DIANA By spouse | ONTY | Common Stock | I | 4,6500 | 5.747 | 27 | 5.747 | ||||
| 2015-04-02 | 2015-03-26 | 4/A | SPIEGELMAN DANIEL K | ONTY | Common Stock | D | 1,5856 | 10.000 | 16 | 40.644 | ||||
| 2015-04-02 | 2015-03-25 | 4/A | SPIEGELMAN DANIEL K | ONTY | Common Stock | D | 1,6271 | 10.000 | 16 | 30.644 | ||||
| 2015-04-01 | 2015-03-26 | 4 | SPIEGELMAN DANIEL K | ONTY | Common Stock | D | 1,5856 | 10.000 | 16 | 40.644 | ||||
| 2015-04-01 | 2015-03-25 | 4 | SPIEGELMAN DANIEL K | ONTY | Common Stock | D | 1,6271 | 10.000 | 16 | 30.644 | ||||
| 2015-03-13 | 2015-03-12 | 4 | James Steven P | ONTY | Restricted Share Unit (RSU) | D | 27.932 | 27.932 | ||||||
| 2015-03-03 | 3 | James Steven P | ONTY | No securities are beneficially owned | D | 0 | ||||||||
| 2015-02-09 | 2015-02-05 | 4 | BVF PARTNERS L P/IL By Biotechnology Value Fund II, L.P. | ONTY | Preferred Stock, $0.0001 per share | I | 1,50 | 1.400 | 1.400 | |||||
| 2015-02-09 | 2015-02-05 | 4 | BVF PARTNERS L P/IL By Biotechnology Value Fund, L.P. | ONTY | Preferred Stock, $0.0001 per share | I | 1,50 | 2.600 | 2.600 | |||||
| 2015-02-09 | 2015-02-05 | 4 | BVF PARTNERS L P/IL By Biotechnology Value Fund II, L.P. | ONTY | Common Stock, $0.0001 par value | I | -1.400.000 | 1.898.293 | ||||||
| 2015-02-09 | 2015-02-05 | 4 | BVF PARTNERS L P/IL By Biotechnology Value Fund, L.P. | ONTY | Common Stock, $0.0001 par value | I | -2.600.000 | 3.762.683 | ||||||
| 2014-12-17 | 3 | LAMPERT MARK N By Biotechnology Value Fund II, L.P. | ONTY | Common Stock, $0.0001 par value | I | 12.446.194 | ||||||||
| 2014-12-17 | 3 | LAMPERT MARK N By Biotechnology Value Fund II, L.P. | ONTY | Common Stock, $0.0001 par value | I | 12.446.194 | ||||||||
| 2014-12-17 | 3 | LAMPERT MARK N By Biotechnology Value Fund, L.P. | ONTY | Common Stock, $0.0001 par value | I | 15.401.402 | ||||||||
| 2014-12-17 | 3 | LAMPERT MARK N By Biotechnology Value Fund, L.P. | ONTY | Common Stock, $0.0001 par value | I | 15.401.402 | ||||||||
| 2014-12-17 | 3 | LAMPERT MARK N By Biotechnology Value Fund II, L.P. | ONTY | Common Stock, $0.0001 par value | I | 12.446.194 | ||||||||
| 2014-12-17 | 3 | LAMPERT MARK N By Biotechnology Value Fund, L.P. | ONTY | Common Stock, $0.0001 par value | I | 15.401.402 | ||||||||
| 2014-12-17 | 3 | LAMPERT MARK N By Biotechnology Value Fund II, L.P. | ONTY | Common Stock, $0.0001 par value | I | 12.446.194 | ||||||||
| 2014-12-17 | 3 | LAMPERT MARK N By Biotechnology Value Fund, L.P. | ONTY | Common Stock, $0.0001 par value | I | 15.401.402 | ||||||||
| 2014-12-17 | 3 | LAMPERT MARK N By Biotechnology Value Fund II, L.P. | ONTY | Common Stock, $0.0001 par value | I | 12.446.194 | ||||||||
| 2014-12-17 | 3 | LAMPERT MARK N By Biotechnology Value Fund, L.P. | ONTY | Common Stock, $0.0001 par value | I | 15.401.402 | ||||||||
| 2014-12-17 | 3 | LAMPERT MARK N By Biotechnology Value Fund II, L.P. | ONTY | Common Stock, $0.0001 par value | I | 12.446.194 | ||||||||
| 2014-12-17 | 3 | LAMPERT MARK N By Biotechnology Value Fund, L.P. | ONTY | Common Stock, $0.0001 par value | I | 15.401.402 | ||||||||
| 2014-12-17 | 2014-12-17 | 4 | BVF PARTNERS L P/IL By Biotechnology Value Fund II, L.P. | ONTY | Common Stock, $0.0001 par value | I | 1,7331 | 55.197 | 96 | 3.298.293 | ||||
| 2014-12-17 | 2014-12-17 | 4 | BVF PARTNERS L P/IL By Biotechnology Value Fund, L.P. | ONTY | Common Stock, $0.0001 par value | I | 1,7331 | 98.298 | 170 | 6.362.683 | ||||
| 2014-12-17 | 2014-12-15 | 4 | BVF PARTNERS L P/IL By Biotechnology Value Fund II, L.P. | ONTY | Common Stock, $0.0001 par value | I | 1,8789 | 79.434 | 149 | 3.243.096 | ||||
| 2014-12-17 | 2014-12-15 | 4 | BVF PARTNERS L P/IL By Biotechnology Value Fund, L.P. | ONTY | Common Stock, $0.0001 par value | I | 1,8789 | 145.515 | 273 | 6.264.385 | ||||
| 2014-12-16 | 2014-12-16 | 4 | HAUSMAN DIANA | ONTY | Stock Option (right to buy) | D | 1,76 | 150.000 | 150.000 | |||||
| 2014-12-16 | 2014-12-16 | 4 | KIRKMAN ROBERT L | ONTY | Stock Option (right to buy) | D | 1,76 | 300.000 | 300.000 | |||||
| 2014-12-16 | 2014-12-16 | 4 | EASTLAND JULIA MARIE | ONTY | Stock Option (right to buy) | D | 1,76 | 100.000 | 100.000 | |||||
| 2014-12-16 | 2014-12-16 | 4 | PETERSON SCOTT ROBERT | ONTY | Stock Option (right to buy) | D | 1,76 | 150.000 | 150.000 | |||||
| 2014-12-16 | 2014-12-16 | 4 | Venkatesan Jay | ONTY | Stock Option (right to buy) | D | 1,76 | 100.000 | 100.000 | |||||
| 2014-12-16 | 2014-12-16 | 4 | Christianson Gary | ONTY | Stock Option (right to buy) | D | 1,76 | 100.000 | 100.000 | |||||
| 2014-10-08 | 2013-07-10 | 4 | SPIEGELMAN DANIEL K | ONTY | Common Stock | D | 1,7201 | -3.403 | -6 | 20.644 | ||||
| 2014-10-08 | 2013-02-20 | 4 | SPIEGELMAN DANIEL K | ONTY | Common Stock | D | 1,9604 | -12.780 | -25 | 24.047 | ||||
| 2014-09-26 | 2014-09-23 | 4/A | Venkatesan Jay By Ayer Special Situations Fund I, LP | ONTY | Common Stock | I | 2,0000 | 250.000 | 500 | 250.000 | ||||
| 2014-09-25 | 2014-09-23 | 4 | Venkatesan Jay By Ayer Special Situations Fund I, LP | ONTY | Common Stock | I | 2,0000 | 250.000 | 500 | 250.000 | ||||
| 2014-09-05 | 2014-09-04 | 4 | Venkatesan Jay | ONTY | Stock Option (right to buy) | D | 2,24 | 100.000 | 100.000 | |||||
| 2014-08-12 | 3 | Venkatesan Jay | ONTY | Common Stock | D | 100.000 | ||||||||
| 2014-08-12 | 3 | Venkatesan Jay | ONTY | Common Stock | D | 100.000 | ||||||||
| 2014-08-12 | 2014-08-08 | 4 | Venkatesan Jay By Andaman Orphan Therapies, LLC | ONTY | Common Stock | I | 263.493 | 263.493 | ||||||
| 2014-08-12 | 2014-08-08 | 4 | Venkatesan Jay | ONTY | Common Stock | D | 3.776.723 | 3.826.723 | ||||||
| 2014-07-16 | 2014-07-16 | 4 | BVF PARTNERS L P/IL By Biotechnology Value Fund II, L.P. | ONTY | Warrants | I | 5,00 | 1,5900 | -242.814 | -386 | 1.223.484 | |||
| 2014-07-16 | 2014-07-16 | 4 | BVF PARTNERS L P/IL By Biotechnology Value Fund, L.P. | ONTY | Warrants | I | 5,00 | 1,5900 | -407.136 | -647 | 2.288.698 | |||
| 2014-07-16 | 2014-07-16 | 4 | BVF PARTNERS L P/IL By Biotechnology Value Fund II, L.P. | ONTY | Common Stock, $0.0001 par value | I | 3,2400 | -258.230 | -837 | 2.412.290 | ||||
| 2014-07-16 | 2014-07-16 | 4 | BVF PARTNERS L P/IL By Biotechnology Value Fund, L.P. | ONTY | Common Stock, $0.0001 par value | I | 3,2400 | -296.008 | -959 | 4.512.523 | ||||
| 2014-06-10 | 2014-06-07 | 4 | HENNEY CHRISTOPHER S | ONTY | Common Stock | D | 3,0600 | -2.044 | -6 | 123.776 | ||||
| 2014-06-10 | 2014-06-06 | 4 | HENNEY CHRISTOPHER S | ONTY | Restricted Share Units (RSU) | D | 16.339 | 16.339 | ||||||
| 2014-06-10 | 2014-06-06 | 4 | LOVE TED W | ONTY | Restricted Share Unit (RSU) | D | 16.339 | 16.339 | ||||||
| 2014-06-10 | 2014-06-07 | 4 | SPIEGELMAN DANIEL K | ONTY | Common Stock | D | 3,0600 | -2.044 | -6 | 36.827 | ||||
| 2014-06-10 | 2014-06-06 | 4 | SPIEGELMAN DANIEL K | ONTY | Restricted Share Unit (RSU) | D | 16.339 | 16.339 | ||||||
| 2014-06-10 | 2014-06-07 | 4 | STOUGHTON W. VICKERY | ONTY | Common Stock | D | 3,0600 | -2.044 | -6 | 46.692 | ||||
| 2014-06-10 | 2014-06-06 | 4 | STOUGHTON W. VICKERY | ONTY | Restricted Share Unit (RSU) | D | 16.339 | 16.339 | ||||||
| 2014-06-10 | 2014-06-07 | 4 | Jackson Richard L. | ONTY | Common Stock | D | 3,0600 | -2.044 | -6 | 47.526 | ||||
| 2014-06-10 | 2014-06-06 | 4 | Jackson Richard L. | ONTY | Restricted Share Unit (RSU) | D | 16.339 | 16.339 | ||||||
| 2014-03-12 | 2014-03-11 | 4 | HENNEY CHRISTOPHER S | ONTY | Restricted Share Unit (RSU) | D | -19.352 | 0 | ||||||
| 2014-03-12 | 2014-03-11 | 4 | HENNEY CHRISTOPHER S | ONTY | Common Stock | D | 3,6500 | -4.838 | -18 | 125.820 | ||||
| 2014-03-12 | 2014-03-11 | 4 | HENNEY CHRISTOPHER S | ONTY | Common Stock | D | 19.352 | 130.658 | ||||||
| 2014-03-12 | 2014-03-11 | 4 | SPIEGELMAN DANIEL K | ONTY | Restricted Share Unit (RSU) | D | -19.352 | 0 | ||||||
| 2014-03-12 | 2014-03-11 | 4 | SPIEGELMAN DANIEL K | ONTY | Common Stock | D | 3,6500 | -4.838 | -18 | 38.871 | ||||
| 2014-03-12 | 2014-03-11 | 4 | SPIEGELMAN DANIEL K | ONTY | Common Stock | D | 19.352 | 43.709 | ||||||
| 2014-03-12 | 2014-03-11 | 4 | STOUGHTON W. VICKERY | ONTY | Restricted Share Unit (RSU) | D | -19.352 | 0 | ||||||
| 2014-03-12 | 2014-03-11 | 4 | STOUGHTON W. VICKERY | ONTY | Common Stock | D | 3,6500 | -4.838 | -18 | 48.736 | ||||
| 2014-03-12 | 2014-03-11 | 4 | STOUGHTON W. VICKERY | ONTY | Common Stock | D | 19.352 | 53.574 | ||||||
| 2014-03-12 | 2014-03-11 | 4 | Jackson Richard L. | ONTY | Restricted Share Unit (RSU) | D | -19.352 | 0 | ||||||
| 2014-03-12 | 2014-03-11 | 4 | Jackson Richard L. | ONTY | Common Stock | D | 3,6500 | -4.838 | -18 | 49.570 | ||||
| 2014-03-12 | 2014-03-11 | 4 | Jackson Richard L. | ONTY | Common Stock | D | 19.352 | 54.408 | ||||||
| 2013-12-16 | 2013-12-12 | 4 | KIRKMAN ROBERT L | ONTY | Stock Option (right to buy) | D | 1,74 | 600.000 | 600.000 | |||||
| 2013-12-16 | 2013-12-12 | 4 | Christianson Gary | ONTY | Stock Option (right to buy) | D | 1,74 | 150.000 | 150.000 | |||||
| 2013-12-16 | 2013-12-12 | 4 | EASTLAND JULIA MARIE | ONTY | Stock Option (right to buy) | D | 1,74 | 150.000 | 150.000 | |||||
| 2013-12-16 | 2013-12-12 | 4 | PETERSON SCOTT ROBERT | ONTY | Stock Option (right to buy) | D | 1,74 | 150.000 | 150.000 | |||||
| 2013-12-16 | 2013-12-12 | 4 | HAUSMAN DIANA | ONTY | Stock Option (right to buy) | D | 1,74 | 150.000 | 150.000 | |||||
| 2013-11-05 | 2013-11-01 | 4 | BVF PARTNERS L P/IL See Explanation of Responses | ONTY | Common Stock | I | 1,7800 | 79.360 | 141 | 2.670.520 | ||||
| 2013-11-05 | 2013-11-01 | 4 | BVF PARTNERS L P/IL See Explanation of Responses | ONTY | Common Stock | I | 1,7800 | 49.640 | 88 | 4.808.531 | ||||
| 2013-09-06 | 3 | LOVE TED W | ONTY | Common Stock | D | 0 | ||||||||
| 2013-09-06 | 2013-09-05 | 4 | LOVE TED W | ONTY | Restricted Share Unit (RSU) | D | 17.341 | 17.341 | ||||||
| 2013-08-12 | 2013-08-08 | 4 | BVF PARTNERS L P/IL See Explanation of Responses | ONTY | Common Stock | I | 1,6495 | 177.940 | 294 | 2.591.160 | ||||
| 2013-08-12 | 2013-08-08 | 4 | BVF PARTNERS L P/IL See Explanation of Responses | ONTY | Common Stock | I | 1,6495 | 80.421 | 133 | 4.758.891 | ||||
| 2013-08-02 | 2013-08-01 | 4 | BVF PARTNERS L P/IL See Explanation of Responses | ONTY | Common Stock | I | 1,7828 | 35.703 | 64 | 2.413.220 | ||||
| 2013-08-02 | 2013-08-01 | 4 | BVF PARTNERS L P/IL See Explanation of Responses | ONTY | Common Stock | I | 1,7828 | 122.641 | 219 | 4.678.470 | ||||
| 2013-08-02 | 2013-07-31 | 4 | BVF PARTNERS L P/IL See Explanation of Responses | ONTY | Common Stock | I | 1,7097 | 179.743 | 307 | 4.555.829 | ||||
| 2013-06-14 | 2013-06-13 | 4 | HENNEY CHRISTOPHER S | ONTY | Restricted Share Units (RSU) | D | 16.042 | 16.042 | ||||||
| 2013-06-14 | 2013-06-13 | 4 | SPIEGELMAN DANIEL K | ONTY | Restricted Share Unit (RSU) | D | 16.042 | 16.042 | ||||||
| 2013-06-14 | 2013-06-13 | 4 | STOUGHTON W. VICKERY | ONTY | Restricted Share Unit (RSU) | D | 16.042 | 16.042 | ||||||
| 2013-06-14 | 2013-06-13 | 4 | WILLIAMS DOUGLAS E | ONTY | Restricted Share Unit (RSU) | D | 16.042 | 16.042 | ||||||
| 2013-06-14 | 2013-06-13 | 4 | Jackson Richard L. | ONTY | Restricted Share Unit (RSU) | D | 16.042 | 16.042 | ||||||
| 2013-06-11 | 2013-06-09 | 4 | HENNEY CHRISTOPHER S | ONTY | Common Stock | D | 1,8600 | -1.135 | -2 | 111.306 | ||||
| 2013-06-11 | 2013-06-09 | 4 | SPIEGELMAN DANIEL K | ONTY | Common Stock | D | 1,8600 | -1.135 | -2 | 24.357 | ||||
| 2013-06-11 | 2013-06-09 | 4 | STOUGHTON W. VICKERY | ONTY | Common Stock | D | 1,8600 | -1.135 | -2 | 34.222 | ||||
| 2013-06-11 | 2013-06-09 | 4 | WILLIAMS DOUGLAS E | ONTY | Common Stock | D | 1,8600 | -1.135 | -2 | 19.961 | ||||
| 2013-06-11 | 2013-06-09 | 4 | Jackson Richard L. | ONTY | Common Stock | D | 1,8600 | -1.135 | -2 | 35.056 | ||||
| 2013-06-07 | 3 | LAMPERT MARK N By Investment 10, L.L.C. | ONTY | Common Stock, $0.0001 par value | I | 1.298.842 | ||||||||
| 2013-06-07 | 3 | LAMPERT MARK N By Biotechnology Value Fund II, L.P. | ONTY | Common Stock, $0.0001 par value | I | 2.303.607 | ||||||||
| 2013-06-07 | 3 | LAMPERT MARK N By Biotechnology Value Fund, L.P. | ONTY | Common Stock, $0.0001 par value | I | 4.235.529 | ||||||||
| 2013-06-07 | 2013-06-07 | 4 | BVF PARTNERS L P/IL See Explanation of Responses | ONTY | Common Stock | I | 1,8304 | 41.526 | 76 | 2.377.517 | ||||
| 2013-06-07 | 2013-06-07 | 4 | BVF PARTNERS L P/IL See Explanation of Responses | ONTY | Common Stock | I | 1,8304 | 74.726 | 137 | 4.376.086 | ||||
| 2013-06-07 | 2013-06-06 | 4 | BVF PARTNERS L P/IL See Explanation of Responses | ONTY | Common Stock | I | 1,7809 | 27.384 | 49 | 2.335.991 | ||||
| 2013-06-07 | 2013-06-06 | 4 | BVF PARTNERS L P/IL See Explanation of Responses | ONTY | Common Stock | I | 1,7809 | 55.531 | 99 | 4.301.360 | ||||
| 2013-06-07 | 2013-06-05 | 4 | BVF PARTNERS L P/IL See Explanation of Responses | ONTY | Common Stock | I | 1,7500 | 5.000 | 9 | 2.308.607 | ||||
| 2013-06-07 | 2013-06-05 | 4 | BVF PARTNERS L P/IL See Explanation of Responses | ONTY | Common Stock | I | 1,7500 | 10.300 | 18 | 4.245.829 | ||||
| 2012-12-14 | 3/A | PETERSON SCOTT ROBERT | ONTY | Common Stock | D | 10.424 | ||||||||
| 2012-12-14 | 2012-12-12 | 4 | KIRKMAN ROBERT L | ONTY | Stock Option (right to buy) | D | 4,74 | 100.000 | 100.000 | |||||
| 2012-12-14 | 2012-12-12 | 4 | Christianson Gary | ONTY | Stock Option (right to buy) | D | 4,74 | 50.000 | 50.000 | |||||
| 2012-12-14 | 2012-12-12 | 4 | EASTLAND JULIA MARIE | ONTY | Stock Option (right to buy) | D | 4,74 | 50.000 | 50.000 | |||||
| 2012-12-14 | 2012-12-12 | 4 | PETERSON SCOTT ROBERT | ONTY | Stock Option (right to buy) | D | 4,74 | 50.000 | 50.000 | |||||
| 2012-12-14 | 2012-12-12 | 4 | HAUSMAN DIANA | ONTY | Stock Option (right to buy) | D | 4,74 | 50.000 | 50.000 | |||||
| 2012-12-11 | 3 | PETERSON SCOTT ROBERT | ONTY | Common Stock | D | 10.424 | ||||||||
| 2012-12-11 | 3 | HAUSMAN DIANA | ONTY | Common Stock | D | 0 | ||||||||
| 2012-06-08 | 2012-06-07 | 4 | STOUGHTON W. VICKERY | ONTY | Common Stock | D | 3,6700 | 8.174 | 30 | 35.357 | ||||
| 2012-06-08 | 2012-06-07 | 4 | WILLIAMS DOUGLAS E | ONTY | Common Stock | D | 3,6700 | 8.174 | 30 | 21.096 | ||||
| 2012-06-08 | 2012-06-07 | 4 | SPIEGELMAN DANIEL K | ONTY | Common Stock | D | 3,6700 | 8.174 | 30 | 25.492 | ||||
| 2012-06-08 | 2012-06-07 | 4 | HENNEY CHRISTOPHER S | ONTY | Common Stock | D | 3,6700 | 8.174 | 30 | 112.441 | ||||
| 2012-06-08 | 2012-06-07 | 4 | Jackson Richard L. | ONTY | Common Stock | D | 3,6700 | 8.174 | 30 | 36.191 | ||||
| 2012-06-05 | 2012-06-03 | 4 | WILLIAMS DOUGLAS E | ONTY | Common Stock | D | 3,5100 | -2.021 | -7 | 12.922 | ||||
| 2012-06-05 | 2012-03-16 | 4 | WILLIAMS DOUGLAS E | ONTY | Common Stock | D | -2.320 | 14.943 | ||||||
| 2012-06-05 | 2012-06-03 | 4 | STOUGHTON W. VICKERY | ONTY | Common Stock | D | 3,5100 | -2.021 | -7 | 27.183 | ||||
| 2012-06-05 | 2012-06-03 | 4 | HENNEY CHRISTOPHER S | ONTY | Common Stock | D | 3,5100 | -2.021 | -7 | 104.267 | ||||
| 2012-06-05 | 2012-06-03 | 4 | SPIEGELMAN DANIEL K | ONTY | Common Stock | D | 3,5100 | -2.021 | -7 | 17.318 | ||||
| 2012-06-05 | 2012-06-03 | 4 | Jackson Richard L. | ONTY | Common Stock | D | 3,5100 | -2.021 | -7 | 28.017 | ||||
| 2012-05-04 | 2012-05-03 | 4 | HENNEY CHRISTOPHER S | ONTY | Restricted Share Units | D | -989 | 0 | ||||||
| 2012-05-04 | 2012-05-03 | 4 | HENNEY CHRISTOPHER S | ONTY | Common Stock | D | 4,1500 | -247 | -1 | 106.288 | ||||
| 2012-05-04 | 2012-05-03 | 4 | HENNEY CHRISTOPHER S | ONTY | Common Stock | D | 989 | 106.535 | ||||||
| 2012-05-04 | 2012-05-03 | 4 | STOUGHTON W. VICKERY | ONTY | Restricted Share Units | D | -989 | 0 | ||||||
| 2012-05-04 | 2012-05-03 | 4 | STOUGHTON W. VICKERY | ONTY | Common Stock | D | 4,1500 | -247 | -1 | 29.204 | ||||
| 2012-05-04 | 2012-05-03 | 4 | STOUGHTON W. VICKERY | ONTY | Common Stock | D | 989 | 29.451 | ||||||
| 2012-05-04 | 2012-05-03 | 4 | Jackson Richard L. | ONTY | Restricted Share Units | D | -989 | 0 | ||||||
| 2012-05-04 | 2012-05-03 | 4 | Jackson Richard L. | ONTY | Common Stock | D | 4,1500 | -247 | -1 | 30.038 | ||||
| 2012-05-04 | 2012-05-03 | 4 | Jackson Richard L. | ONTY | Common Stock | D | 989 | 30.285 | ||||||
| 2012-01-03 | 2011-12-31 | 4 | STOUGHTON W. VICKERY | ONTY | Restricted Share Units | D | -2.388 | 0 | ||||||
| 2012-01-03 | 2011-12-31 | 4 | STOUGHTON W. VICKERY | ONTY | Common Stock | D | 7,5800 | -597 | -5 | 28.462 | ||||
| 2012-01-03 | 2011-12-31 | 4 | STOUGHTON W. VICKERY | ONTY | Common Stock | D | 2.388 | 29.059 | ||||||
| 2012-01-03 | 2011-12-31 | 4 | HENNEY CHRISTOPHER S | ONTY | Restricted Share Units | D | -2.388 | 0 | ||||||
| 2012-01-03 | 2011-12-31 | 4 | HENNEY CHRISTOPHER S | ONTY | Common Stock | D | 7,5800 | -597 | -5 | 105.546 | ||||
| 2012-01-03 | 2011-12-31 | 4 | HENNEY CHRISTOPHER S | ONTY | Common Stock | D | 2.388 | 106.143 | ||||||
| 2012-01-03 | 2011-12-31 | 4 | Jackson Richard L. | ONTY | Restricted Share Units | D | -2.388 | 0 | ||||||
| 2012-01-03 | 2011-12-31 | 4 | Jackson Richard L. | ONTY | Common Stock | D | 7,5800 | -597 | -5 | 29.296 | ||||
| 2012-01-03 | 2011-12-31 | 4 | Jackson Richard L. | ONTY | Common Stock | D | 2.388 | 29.893 | ||||||
| 2009-10-06 | 3 | WILLIAMS DOUGLAS E | ONTY | No securities are beneficially owned | D | 0 |
