| Insider-Aktien | 9.919.768 shares |
Insider-Stimmungswert
Der Insider-Stimmungswert ermittelt die Unternehmen, die von Unternehmensinsidern gekauft werden.
Es ist das Ergebnis eines ausgeklügelten quantitativen Multifaktormodells, das die Unternehmen mit der höchsten Insiderakkumulation identifiziert. Das Scoring-Modell verwendet eine Kombination aus der Nettozahl der Insiderkäufe der letzten 90 Tage, der Gesamtzahl der gekauften Aktien als Prozentsatz des Streubesitzes und der Gesamtzahl der von Insidern gehaltenen Aktien. Die Zahl reicht von 0 bis 100, wobei höhere Zahlen ein höheres Maß an Insiderkäufen anzeigen als bei anderen Unternehmen und 50 den Durchschnitt darstellt.
Aktualisierungshäufigkeit: Täglich
Führungskräfte-Stimmungswert
Der Führungskräfte-Stimmungswert findet Unternehmen, die von Führungskräften des Unternehmens gekauft werden.
Per Definition sind Führungskräfte des Unternehmens Insider, aber im Gegensatz zu anderen Insidern (10%ige Aktionäre und Vorstandsmitglieder) arbeiten Führungskräfte täglich für das Unternehmen und verwenden beim Handel ihr eigenes Geld. (10%ige Aktionäre und Vorstandsmitglieder sind oft Fondsmanager, die das Geld anderer Leute verwalten.) Daher sind Insider-Geschäfte, die von Führungskräften getätigt werden, viel bedeutender und sollten entsprechend behandelt werden.
Wie der Insider-Stimmungswert ist auch der Führungskräfte-Stimmungswert das Ergebnis eines ausgeklügelten quantitativen Multifaktormodells, das die Unternehmen mit der höchsten Führungskräftekonzentration identifiziert.
Aktualisierungshäufigkeit: Täglich
Wichtige Insider-Kennzahlen
Diese Karte zeigt, wie das Unternehmen bei verschiedenen Insider-Kennzahlen abschneidet. Der Perzentil-Rang zeigt, wie dieses Unternehmen im Vergleich zu anderen Unternehmen auf den US-Märkten abschneidet. Höhere Ränge deuten auf eine bessere Situation hin.
Es ist beispielsweise allgemein anerkannt, dass Insiderkäufe ein positiver Indikator sind, so dass Unternehmen mit mehr Insiderkäufen besser abschneiden würden als Unternehmen mit weniger Insiderkäufen (oder sogar Insiderverkäufen).
Nettoanzahl der Insider, die kaufen (Rang)
Die Nettoanzahl der Insiderkäufe ist die Gesamtzahl der Insiderkäufe abzüglich der Gesamtzahl der Insiderverkäufe in den letzten 90 Tagen. Der Perzentilrang wird hier angezeigt (Bereich von 0 bis 100%).
Prozent des Streubesitzes von Insidern gekauft (Rang)
Prozent des von Insidern gekauften Streubesitzes ist die Gesamtzahl der von Insidern gekauften Aktien abzüglich der Gesamtzahl der von Insidern in den letzten 90 Tagen verkauften Aktien, geteilt durch den gesamten Streubesitz und multipliziert mit 100.
Diagramm zum Insiderhandel
Otonomy Inc Insider-Trades sind in der folgenden Grafik dargestellt. Insider sind leitende Angestellte, Direktoren oder bedeutende Investoren in einem Unternehmen. Im Allgemeinen ist es für Insider illegal, auf der Grundlage von wesentlichen, nicht-öffentlichen Informationen mit Aktien ihrer Unternehmen zu handeln. Das bedeutet nicht, dass es für sie illegal ist, irgendwelche Geschäfte in ihren eigenen Unternehmen zu tätigen. Sie müssen jedoch alle Geschäfte der SEC über ein Formular 4 melden.
Kennzahlen zu Insiderlisten und Rentabilität
Diese Tabelle zeigt die Liste der bekannten Insider und wird automatisch aus den bei der SEC eingereichten Unterlagen erstellt. Zusätzlich zu den Namen, dem letzten Titel und der Bezeichnung als Direktor, leitender Angestellter oder 10%-iger Anteilseigner geben wir die zuletzt veröffentlichten Bestände an. Zusätzlich stellen wir, wenn möglich, die historische Handelsperformance für den Insider zur Verfügung. Die historische Handelsperformance ist ein gewichteter Durchschnitt der Performance tatsächlicher offener Kauftransaktionen, die von dem Insider getätigt wurden. Weitere Informationen zur Berechnung dieses Wertes finden Sie in diesem YouTube-Webinar.
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| Insider | Durchschnittlicher Gewinn (%) | Aktien in Besitz |
Split Angepasst |
|---|
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Erfolgsbilanz der Insiderkäufe - Kurzfristige Gewinnanalyse
In diesem Abschnitt analysieren wir die Rentabilität jedes ungeplanten Insiderkaufs, der auf dem freien Markt in OTIC / Otonomy Inc getätigt wurde. Diese Analyse hilft zu verstehen, ob der Insider beständig abnormale Renditen erzielt und es sich lohnt, ihm zu folgen. Diese Analyse bezieht sich auf ein Jahr nach jedem Handel, und die Ergebnisse sind theoretisch .
Die folgende Tabelle zeigt die jüngsten Käufe am offenen Markt, die nicht Teil eines automatischen Handelsplans waren.
Bereinigter Preis ist der splitbereinigte Preis. Bereinigte Aktien sind die um den Split bereinigten Aktien.
Erfolgsbilanz von Insiderverkäufen - Kurzfristige Verlustanalyse
In diesem Abschnitt analysieren wir die kurzfristige Verlustvermeidung jedes ungeplanten Insider-Verkaufs auf dem freien Markt in OTIC / Otonomy Inc. Ein konsistentes Muster der Verlustvermeidung kann darauf hindeuten, dass zukünftige Verkaufstransaktionen Kursrückgänge vorhersagen können. Diese Analyse bezieht sich auf ein Jahr nach jedem Handel, und die Ergebnisse sind theoretisch .
Die folgende Tabelle zeigt die jüngsten Verkäufe am offenen Markt, die nicht Teil eines automatischen Handelsplans waren.
Bereinigter Preis ist der splitbereinigte Preis. Bereinigte Aktien sind die um den Split bereinigten Aktien.
Transaktionshistorie
Klicken Sie auf das Link-Symbol, um den vollständigen Transaktionsverlauf anzuzeigen. Transaktionen, die im Rahmen eines automatischen Handelsplans 10b5-1 gemeldet werden, sind in der Spalte 10b-5 mit einem X gekennzeichnet.
| Datei Datum |
Handel Datum |
Form | Insider | Ticker | Wertpapier-Titel | Code | Direkt | Ausführung Preis |
Einheit Preis |
Eimheiten Verändert |
Wert Geändert (1K) |
Verbleibende Optionen |
Verbleibende Aktien |
|
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2022-12-30 | 2022-12-30 | 4 | Weber David Allen | OTIC | Common Stock | D | 0,0880 | -91.636 | -8 | 285.863 | ||||
| 2022-12-30 | 2022-12-28 | 4 | Cayer Paul E | OTIC | Common Stock | D | 0,0870 | -40.054 | -3 | 183.733 | ||||
| 2022-11-29 | 2022-11-28 | 4 | CAPPS VICKIE L | OTIC | Common Stock | D | 0,1028 | -42.242 | -4 | 3.400 | ||||
| 2022-03-29 | 2022-03-28 | 4 | Weber David Allen | OTIC | Common Stock | D | 2,4130 | -11.243 | -27 | 377.499 | ||||
| 2022-03-29 | 2022-03-25 | 4 | Weber David Allen | OTIC | Common Stock | D | 2,3880 | -8.026 | -19 | 388.742 | ||||
| 2022-03-29 | 2022-03-28 | 4 | Savel Robert Michael II | OTIC | Common Stock | D | 2,4130 | -3.325 | -8 | 145.735 | ||||
| 2022-03-29 | 2022-03-25 | 4 | Savel Robert Michael II | OTIC | Common Stock | D | 2,3880 | -2.374 | -6 | 149.060 | ||||
| 2022-03-29 | 2022-03-28 | 4 | Foster Alan Charles | OTIC | Common Stock | D | 2,4130 | -2.559 | -6 | 177.017 | ||||
| 2022-03-29 | 2022-03-25 | 4 | Foster Alan Charles | OTIC | Common Stock | D | 2,3880 | -1.827 | -4 | 179.576 | ||||
| 2022-03-29 | 2022-03-28 | 4 | Cayer Paul E | OTIC | Common Stock | D | 2,4130 | -5.624 | -14 | 223.787 | ||||
| 2022-03-29 | 2022-03-25 | 4 | Cayer Paul E | OTIC | Common Stock | D | 2,3880 | -4.015 | -10 | 229.411 | ||||
| 2022-01-19 | 2022-01-14 | 4 | Foster Alan Charles | OTIC | Stock Option (right to buy) | D | 2,03 | 130.000 | 130.000 | |||||
| 2022-01-19 | 2022-01-14 | 4 | Foster Alan Charles | OTIC | Common Stock | D | 70.000 | 181.403 | ||||||
| 2022-01-19 | 2022-01-14 | 4 | Cayer Paul E | OTIC | Stock Option (right to buy) | D | 2,03 | 250.000 | 250.000 | |||||
| 2022-01-19 | 2022-01-14 | 4 | Cayer Paul E | OTIC | Common Stock | D | 100.000 | 233.426 | ||||||
| 2022-01-19 | 2022-01-14 | 4 | Weber David Allen | OTIC | Stock Option (right to buy) | D | 2,03 | 500.000 | 500.000 | |||||
| 2022-01-19 | 2022-01-14 | 4 | Weber David Allen | OTIC | Common Stock | D | 150.000 | 396.768 | ||||||
| 2022-01-19 | 2022-01-14 | 4 | Savel Robert Michael II | OTIC | Stock Option (right to buy) | D | 2,03 | 130.000 | 130.000 | |||||
| 2022-01-19 | 2022-01-14 | 4 | Savel Robert Michael II | OTIC | Common Stock | D | 70.000 | 151.434 | ||||||
| 2021-08-20 | 2021-08-18 | 4 | Broadfoot Jill Marie | OTIC | Stock Option (right to buy) | D | 1,42 | 35.000 | 35.000 | |||||
| 2021-06-24 | 2021-06-22 | 4 | McGill Iain | OTIC | Stock Option (right to buy) | D | 2,18 | 17.500 | 17.500 | |||||
| 2021-06-24 | 2021-06-22 | 4 | Schroeder Theodore R | OTIC | Stock Option (right to buy) | D | 2,18 | 17.500 | 17.500 | |||||
| 2021-06-24 | 2021-06-22 | 4 | Lichter Jay | OTIC | Stock Option (right to buy) | D | 2,18 | 17.500 | 17.500 | |||||
| 2021-06-24 | 2021-06-22 | 4 | CAPPS VICKIE L | OTIC | Stock Option (right to buy) | D | 2,18 | 17.500 | 17.500 | |||||
| 2021-06-24 | 2021-06-22 | 4 | Kennedy Ciara | OTIC | Stock Option (right to buy) | D | 2,18 | 17.500 | 17.500 | |||||
| 2021-06-24 | 2021-06-22 | 4 | BREITMEYER JAMES B | OTIC | Stock Option (right to buy) | D | 2,18 | 17.500 | 17.500 | |||||
| 2021-04-20 | 3 | Foster Alan Charles | OTIC | Common Stock | D | 51.403 | ||||||||
| 2021-04-20 | 2021-04-16 | 4 | Savel Robert Michael II | OTIC | Common Stock | D | 65.000 | 81.434 | ||||||
| 2021-04-20 | 2021-04-16 | 4 | Cayer Paul E | OTIC | Common Stock | D | 110.000 | 133.426 | ||||||
| 2021-04-20 | 2021-04-16 | 4 | Weber David Allen | OTIC | Common Stock | D | 220.000 | 246.768 | ||||||
| 2021-03-03 | 2021-03-03 | 4 | Lichter Jay | OTIC | Common Stock | I | 2,6980 | -113.935 | -307 | 0 | ||||
| 2021-03-03 | 2021-03-03 | 4 | Lichter Jay | OTIC | Common Stock | I | 2,6980 | -207.245 | -559 | 0 | ||||
| 2021-03-02 | 2021-03-02 | 4 | Lichter Jay | OTIC | Common Stock | I | 2,8990 | -138.199 | -401 | 113.935 | ||||
| 2021-03-02 | 2021-03-02 | 4 | Lichter Jay | OTIC | Common Stock | I | 2,8990 | -251.375 | -729 | 207.245 | ||||
| 2021-03-02 | 2021-03-01 | 4 | Lichter Jay | OTIC | Common Stock | I | 2,8560 | -61.619 | -176 | 252.134 | ||||
| 2021-03-02 | 2021-03-01 | 4 | Lichter Jay | OTIC | Common Stock | I | 2,8560 | -112.081 | -320 | 458.620 | ||||
| 2021-03-02 | 2021-02-26 | 4 | Lichter Jay | OTIC | Common Stock | I | 2,8300 | -117.262 | -332 | 313.753 | ||||
| 2021-03-02 | 2021-02-26 | 4 | Lichter Jay | OTIC | Common Stock | I | 2,8300 | -213.292 | -604 | 570.701 | ||||
| 2021-02-25 | 2021-02-25 | 4 | Lichter Jay | OTIC | Common Stock | I | 2,9540 | -110.361 | -326 | 431.015 | ||||
| 2021-02-25 | 2021-02-25 | 4 | Lichter Jay | OTIC | Common Stock | I | 2,9540 | -200.739 | -593 | 783.993 | ||||
| 2021-02-25 | 2021-02-24 | 4 | Lichter Jay | OTIC | Common Stock | I | 2,9820 | -178.484 | -532 | 541.376 | ||||
| 2021-02-25 | 2021-02-24 | 4 | Lichter Jay | OTIC | Common Stock | I | 2,9820 | -324.651 | -968 | 984.732 | ||||
| 2021-02-25 | 2021-02-23 | 4 | Lichter Jay | OTIC | Common Stock | I | 2,8880 | -95.113 | -275 | 719.860 | ||||
| 2021-02-25 | 2021-02-23 | 4 | Lichter Jay | OTIC | Common Stock | I | 2,8880 | -173.005 | -500 | 1.309.383 | ||||
| 2021-01-20 | 2021-01-15 | 4 | Savel Robert Michael II | OTIC | Stock Option (right to buy) | D | 5,20 | 150.000 | 150.000 | |||||
| 2021-01-20 | 2021-01-15 | 4 | Cayer Paul E | OTIC | Stock Option (right to buy) | D | 5,20 | 250.000 | 250.000 | |||||
| 2021-01-20 | 2021-01-15 | 4 | Weber David Allen | OTIC | Stock Option (right to buy) | D | 5,20 | 500.000 | 500.000 | |||||
| 2020-06-25 | 2020-06-23 | 4 | CAPPS VICKIE L | OTIC | Stock Option (right to buy) | D | 3,56 | 17.500 | 17.500 | |||||
| 2020-06-25 | 2020-06-23 | 4 | Kennedy Ciara | OTIC | Stock Option (right to buy) | D | 3,56 | 17.500 | 17.500 | |||||
| 2020-06-25 | 2020-06-23 | 4 | Lichter Jay | OTIC | Stock Option (right to buy) | D | 3,56 | 17.500 | 17.500 | |||||
| 2020-06-25 | 2020-06-23 | 4 | McGill Iain | OTIC | Stock Option (right to buy) | D | 3,56 | 17.500 | 17.500 | |||||
| 2020-06-25 | 2020-06-23 | 4 | BREITMEYER JAMES B | OTIC | Stock Option (right to buy) | D | 3,56 | 17.500 | 17.500 | |||||
| 2020-06-25 | 2020-06-23 | 4 | Schroeder Theodore R | OTIC | Stock Option (right to buy) | D | 3,56 | 17.500 | 17.500 | |||||
| 2020-03-02 | 3 | Kennedy Ciara | OTIC | No securities of the Issuer are beneficially owned. | D | 0 | ||||||||
| 2020-03-02 | 2020-03-01 | 4 | Kennedy Ciara | OTIC | Stock Option (right to buy) | D | 3,15 | 35.000 | 35.000 | |||||
| 2020-01-17 | 2020-01-15 | 4 | Cayer Paul E | OTIC | Stock Option (right to buy) | D | 3,54 | 490.000 | 490.000 | |||||
| 2020-01-17 | 2020-01-15 | 4 | Savel Robert Michael II | OTIC | Stock Option (right to buy) | D | 3,54 | 250.000 | 250.000 | |||||
| 2020-01-17 | 2020-01-15 | 4 | Weber David Allen | OTIC | Stock Option (right to buy) | D | 3,54 | 700.000 | 700.000 | |||||
| 2019-06-13 | 2019-06-11 | 4 | CAPPS VICKIE L | OTIC | Stock Option (right to buy) | D | 2,35 | 17.500 | 17.500 | |||||
| 2019-06-13 | 2019-06-11 | 4 | BREITMEYER JAMES B | OTIC | Stock Option (right to buy) | D | 2,35 | 17.500 | 17.500 | |||||
| 2019-06-13 | 2019-06-11 | 4 | Preston Heather | OTIC | Stock Option (right to buy) | D | 2,35 | 17.500 | 17.500 | |||||
| 2019-06-13 | 2019-06-11 | 4 | Lichter Jay | OTIC | Stock Option (right to buy) | D | 2,35 | 17.500 | 17.500 | |||||
| 2019-06-13 | 2019-06-11 | 4 | McGill Iain | OTIC | Stock Option (right to buy) | D | 2,35 | 17.500 | 17.500 | |||||
| 2019-06-13 | 2019-06-11 | 4 | Schroeder Theodore R | OTIC | Stock Option (right to buy) | D | 2,35 | 17.500 | 17.500 | |||||
| 2019-01-17 | 2019-01-15 | 4 | Savel Robert Michael II | OTIC | Stock Option (right to buy) | D | 2,02 | 200.000 | 200.000 | |||||
| 2019-01-17 | 2019-01-15 | 4 | Bishop Katherine Mary | OTIC | Stock Option (right to buy) | D | 2,02 | 215.000 | 215.000 | |||||
| 2019-01-17 | 2019-01-15 | 4 | Cayer Paul E | OTIC | Stock Option (right to buy) | D | 2,02 | 225.000 | 225.000 | |||||
| 2019-01-17 | 2019-01-15 | 4 | Weber David Allen | OTIC | Stock Option (right to buy) | D | 2,02 | 800.000 | 800.000 | |||||
| 2018-12-26 | 2018-12-21 | 4 | Weber David Allen | OTIC | Stock Option (right to buy) | D | 5,80 | 250.000 | 250.000 | |||||
| 2018-06-20 | 2018-06-19 | 4 | CAPPS VICKIE L | OTIC | Stock Option (right to buy) | D | 4,45 | 17.500 | 17.500 | |||||
| 2018-06-20 | 2018-06-19 | 4 | Preston Heather | OTIC | Stock Option (right to buy) | D | 4,45 | 17.500 | 17.500 | |||||
| 2018-06-20 | 2018-06-19 | 4 | McGill Iain | OTIC | Stock Option (right to buy) | D | 4,45 | 17.500 | 17.500 | |||||
| 2018-06-20 | 3 | BREITMEYER JAMES B | OTIC | No securities are beneficially owned. | D | 0 | ||||||||
| 2018-06-20 | 2018-06-19 | 4 | BREITMEYER JAMES B | OTIC | Stock Option (right to buy) | D | 4,45 | 35.000 | 35.000 | |||||
| 2018-06-20 | 2018-06-19 | 4 | Schroeder Theodore R | OTIC | Stock Option (right to buy) | D | 4,45 | 17.500 | 17.500 | |||||
| 2018-06-20 | 2018-06-19 | 4 | Lichter Jay | OTIC | Stock Option (right to buy) | D | 4,45 | 17.500 | 17.500 | |||||
| 2018-02-05 | 2018-02-01 | 4 | LOUMEAU ERIC J | OTIC | Employee Stock Option (right to buy) | D | 5,80 | 110.000 | 110.000 | |||||
| 2018-02-05 | 2018-02-01 | 4 | Savel Robert Michael II | OTIC | Employee Stock Option (right to buy) | D | 5,80 | 165.000 | 165.000 | |||||
| 2018-02-05 | 2018-02-01 | 4 | Weber David Allen | OTIC | Employee Stock Option (right to buy) | D | 5,80 | 400.000 | 400.000 | |||||
| 2018-02-05 | 2018-02-01 | 4 | Bishop Katherine Mary | OTIC | Employee Stock Option (right to buy) | D | 5,80 | 155.000 | 155.000 | |||||
| 2018-02-05 | 2018-02-01 | 4 | Cayer Paul E | OTIC | Employee Stock Option (right to buy) | D | 5,80 | 130.000 | 130.000 | |||||
| 2018-01-23 | 2018-01-19 | 4 | Bishop Katherine Mary | OTIC | Employee Stock Option (right to buy) | D | 5,68 | 100.000 | 100.000 | |||||
| 2018-01-23 | 2018-01-19 | 4 | Bishop Katherine Mary | OTIC | Employee Stock Option (right to buy) | D | 16,20 | -150.000 | 0 | |||||
| 2018-01-23 | 2018-01-19 | 4 | LOUMEAU ERIC J | OTIC | Employee Stock Option (right to buy) | D | 5,68 | 33.333 | 33.333 | |||||
| 2018-01-23 | 2018-01-19 | 4 | LOUMEAU ERIC J | OTIC | Employee Stock Option (right to buy) | D | 5,68 | 46.666 | 46.666 | |||||
| 2018-01-23 | 2018-01-19 | 4 | LOUMEAU ERIC J | OTIC | Employee Stock Option (right to buy) | D | 5,68 | 66.666 | 66.666 | |||||
| 2018-01-23 | 2018-01-19 | 4 | LOUMEAU ERIC J | OTIC | Employee Stock Option (right to buy) | D | 14,00 | -50.000 | 0 | |||||
| 2018-01-23 | 2018-01-19 | 4 | LOUMEAU ERIC J | OTIC | Employee Stock Option (right to buy) | D | 14,44 | -70.000 | 0 | |||||
| 2018-01-23 | 2018-01-19 | 4 | LOUMEAU ERIC J | OTIC | Employee Stock Option (right to buy) | D | 31,59 | -100.000 | 0 | |||||
| 2018-01-23 | 2018-01-19 | 4 | Cayer Paul E | OTIC | Employee Stock Option (right to buy) | D | 5,68 | 46.666 | 46.666 | |||||
| 2018-01-23 | 2018-01-19 | 4 | Cayer Paul E | OTIC | Employee Stock Option (right to buy) | D | 5,68 | 46.666 | 46.666 | |||||
| 2018-01-23 | 2018-01-19 | 4 | Cayer Paul E | OTIC | Employee Stock Option (right to buy) | D | 5,68 | 40.000 | 40.000 | |||||
| 2018-01-23 | 2018-01-19 | 4 | Cayer Paul E | OTIC | Employee Stock Option (right to buy) | D | 14,00 | -70.000 | 0 | |||||
| 2018-01-23 | 2018-01-19 | 4 | Cayer Paul E | OTIC | Employee Stock Option (right to buy) | D | 14,44 | -70.000 | 0 | |||||
| 2018-01-23 | 2018-01-19 | 4 | Cayer Paul E | OTIC | Employee Stock Option (right to buy) | D | 34,12 | -60.000 | 0 | |||||
| 2018-01-23 | 2018-01-19 | 4 | Savel Robert Michael II | OTIC | Employee Stock Option (right to buy) | D | 5,68 | 33.333 | 33.333 | |||||
| 2018-01-23 | 2018-01-19 | 4 | Savel Robert Michael II | OTIC | Employee Stock Option (right to buy) | D | 5,68 | 36.666 | 36.666 | |||||
| 2018-01-23 | 2018-01-19 | 4 | Savel Robert Michael II | OTIC | Employee Stock Option (right to buy) | D | 5,68 | 20.000 | 20.000 | |||||
| 2018-01-23 | 2018-01-19 | 4 | Savel Robert Michael II | OTIC | Employee Stock Option (right to buy) | D | 14,00 | -50.000 | 0 | |||||
| 2018-01-23 | 2018-01-19 | 4 | Savel Robert Michael II | OTIC | Employee Stock Option (right to buy) | D | 14,44 | -55.000 | 0 | |||||
| 2018-01-23 | 2018-01-19 | 4 | Savel Robert Michael II | OTIC | Employee Stock Option (right to buy) | D | 34,12 | -30.000 | 0 | |||||
| 2018-01-23 | 2018-01-19 | 4 | Weber David Allen | OTIC | Employee Stock Option (right to buy) | D | 5,68 | 133.333 | 133.333 | |||||
| 2018-01-23 | 2018-01-19 | 4 | Weber David Allen | OTIC | Employee Stock Option (right to buy) | D | 5,68 | 153.333 | 153.333 | |||||
| 2018-01-23 | 2018-01-19 | 4 | Weber David Allen | OTIC | Employee Stock Option (right to buy) | D | 5,68 | 86.666 | 86.666 | |||||
| 2018-01-23 | 2018-01-19 | 4 | Weber David Allen | OTIC | Employee Stock Option (right to buy) | D | 14,00 | -200.000 | 0 | |||||
| 2018-01-23 | 2018-01-19 | 4 | Weber David Allen | OTIC | Employee Stock Option (right to buy) | D | 14,44 | -230.000 | 0 | |||||
| 2018-01-23 | 2018-01-19 | 4 | Weber David Allen | OTIC | Employee Stock Option (right to buy) | D | 34,12 | -130.000 | 0 | |||||
| 2017-09-05 | 2017-08-31 | 4 | Lichter Jay | OTIC | Warrant to Purchase Common Stock (Right to Buy) | I | 14,18 | -14.106 | 0 | |||||
| 2017-09-05 | 2017-08-31 | 4 | Lichter Jay | OTIC | Warrant to Purchase Common Stock (Right to Buy) | I | 14,18 | -14.106 | 0 | |||||
| 2017-09-05 | 2017-08-31 | 4 | Lichter Jay | OTIC | Warrant to Purchase Common Stock (Right to Buy) | I | 14,18 | -14.106 | 0 | |||||
| 2017-09-05 | 2017-08-31 | 4 | Lichter Jay | OTIC | Warrant to Purchase Common Stock (Right to Buy) | I | 14,18 | -14.106 | 0 | |||||
| 2017-09-05 | 2017-08-31 | 4 | Lichter Jay | OTIC | Warrant to Purchase Common Stock (Right to Buy) | I | 14,18 | -14.106 | 0 | |||||
| 2017-09-05 | 2017-08-31 | 4 | Lichter Jay | OTIC | Warrant to Purchase Common Stock (Right to Buy) | I | 14,18 | -14.106 | 0 | |||||
| 2017-09-05 | 2017-08-31 | 4 | Lichter Jay | OTIC | Warrant to Purchase Common Stock (Right to Buy) | I | 14,18 | -14.106 | 0 | |||||
| 2017-09-05 | 2017-08-31 | 4 | Lichter Jay | OTIC | Warrant to Purchase Common Stock (Right to Buy) | I | 14,18 | -14.106 | 0 | |||||
| 2017-09-05 | 2017-08-31 | 4 | Lichter Jay | OTIC | Warrant to Purchase Common Stock (Right to Buy) | I | 14,18 | -14.106 | 0 | |||||
| 2017-09-05 | 2017-08-31 | 4 | Lichter Jay | OTIC | Warrant to Purchase Common Stock (Right to Buy) | I | 14,18 | -14.106 | 0 | |||||
| 2017-09-05 | 2017-08-31 | 4 | Lichter Jay | OTIC | Common Stock | I | 18,3700 | -108.851 | -2.000 | 2.297.361 | ||||
| 2017-09-05 | 2017-08-31 | 4 | Lichter Jay | OTIC | Common Stock | I | 14,1800 | 141.060 | 2.000 | 2.406.212 | ||||
| 2017-07-14 | 2017-06-20 | 4 | Schroeder Theodore R | OTIC | Stock Option (right to buy) | D | 16,05 | 15.000 | 15.000 | |||||
| 2017-07-14 | 2017-06-20 | 4 | McGill Iain | OTIC | Stock Option (right to buy) | D | 16,05 | 15.000 | 15.000 | |||||
| 2017-07-14 | 2017-06-20 | 4 | MORROW GEORGE J | OTIC | Stock Option (right to buy) | D | 16,05 | 15.000 | 15.000 | |||||
| 2017-07-14 | 2017-06-20 | 4 | Preston Heather | OTIC | Stock Option (right to buy) | D | 16,05 | 15.000 | 15.000 | |||||
| 2017-07-14 | 2017-06-20 | 4 | CAPPS VICKIE L | OTIC | Stock Option (right to buy) | D | 16,05 | 15.000 | 15.000 | |||||
| 2017-07-14 | 2017-06-20 | 4 | Lichter Jay | OTIC | Stock Option (right to buy) | D | 16,05 | 15.000 | 15.000 | |||||
| 2017-06-27 | 2017-06-26 | 4 | LOUMEAU ERIC J | OTIC | Common Stock | D | 18,7500 | -1.206 | -23 | 0 | ||||
| 2017-06-27 | 2017-06-23 | 4 | LOUMEAU ERIC J | OTIC | Common Stock | D | 18,5000 | -2.316 | -43 | 1.206 | ||||
| 2017-06-27 | 2017-06-01 | 4 | LOUMEAU ERIC J | OTIC | Common Stock | D | 11,4300 | 1.206 | 14 | 3.522 | ||||
| 2017-06-27 | 2016-12-01 | 4 | LOUMEAU ERIC J | OTIC | Common Stock | D | 13,0500 | 647 | 8 | 2.316 | ||||
| 2017-06-27 | 2016-06-01 | 4 | LOUMEAU ERIC J | OTIC | Common Stock | D | 13,1300 | 1.021 | 13 | 1.669 | ||||
| 2017-06-27 | 2015-12-01 | 4 | LOUMEAU ERIC J | OTIC | Common Stock | D | 20,3700 | 648 | 13 | 648 | ||||
| 2017-03-08 | 2017-03-06 | 4 | LOUMEAU ERIC J | OTIC | Employee Stock Option (right to buy) | D | 14,00 | 50.000 | 50.000 | |||||
| 2017-03-08 | 2017-03-06 | 4 | Weber David Allen | OTIC | Employee Stock Option (right to buy) | D | 14,00 | 200.000 | 200.000 | |||||
| 2017-03-08 | 2017-03-06 | 4 | Cayer Paul E | OTIC | Employee Stock Option (right to buy) | D | 14,00 | 70.000 | 70.000 | |||||
| 2017-03-08 | 2017-03-06 | 4 | Hakanson Dean | OTIC | Employee Stock Option (right to buy) | D | 14,00 | 65.000 | 65.000 | |||||
| 2017-03-08 | 2017-03-06 | 4 | Savel Robert Michael II | OTIC | Employee Stock Option (right to buy) | D | 14,00 | 50.000 | 50.000 | |||||
| 2017-01-06 | 3 | Bishop Katherine Mary | OTIC | Common Stock | D | 3.270 | ||||||||
| 2017-01-06 | 3 | Bishop Katherine Mary | OTIC | Common Stock | D | 3.270 | ||||||||
| 2017-01-06 | 2017-01-04 | 4 | Bishop Katherine Mary | OTIC | Employee Stock Option (right to buy) | D | 16,20 | 150.000 | 150.000 | |||||
| 2016-11-22 | 2016-11-21 | 4 | LeBel Carl | OTIC | Employee Stock Option (right to buy) | D | 3,17 | -1.456 | 12.803 | |||||
| 2016-11-22 | 2016-11-21 | 4 | LeBel Carl | OTIC | Common Stock | D | 18,0650 | -1.456 | -26 | 9.458 | ||||
| 2016-11-22 | 2016-11-21 | 4 | LeBel Carl | OTIC | Common Stock | D | 3,1700 | 1.456 | 5 | 10.914 | ||||
| 2016-11-22 | 2016-11-18 | 4 | LeBel Carl | OTIC | Employee Stock Option (right to buy) | D | 3,17 | -5.626 | 14.259 | |||||
| 2016-11-22 | 2016-11-18 | 4 | LeBel Carl | OTIC | Employee Stock Option (right to buy) | D | 6,33 | -3.543 | 31.891 | |||||
| 2016-11-22 | 2016-11-18 | 4 | LeBel Carl | OTIC | Common Stock | D | 18,0721 | -9.169 | -166 | 9.458 | ||||
| 2016-11-22 | 2016-11-18 | 4 | LeBel Carl | OTIC | Common Stock | D | 3,1700 | 5.626 | 18 | 18.627 | ||||
| 2016-11-22 | 2016-11-18 | 4 | LeBel Carl | OTIC | Common Stock | D | 6,3300 | 3.543 | 22 | 13.001 | ||||
| 2016-09-08 | 2016-09-06 | 4 | LeBel Carl | OTIC | Employee Stock Option (right to buy) | D | 3,17 | -5.304 | 19.885 | |||||
| 2016-09-08 | 2016-09-06 | 4 | LeBel Carl | OTIC | Employee Stock Option (right to buy) | D | 6,33 | -15.946 | 35.434 | |||||
| 2016-09-08 | 2016-09-06 | 4 | LeBel Carl | OTIC | Common Stock | D | 17,9500 | -5.304 | -95 | 9.458 | ||||
| 2016-09-08 | 2016-09-06 | 4 | LeBel Carl | OTIC | Common Stock | D | 17,9500 | -3.813 | -68 | 14.762 | ||||
| 2016-09-08 | 2016-09-06 | 4 | LeBel Carl | OTIC | Common Stock | D | 17,9500 | -12.133 | -218 | 18.575 | ||||
| 2016-09-08 | 2016-09-06 | 4 | LeBel Carl | OTIC | Common Stock | D | 3,1700 | 5.304 | 17 | 30.708 | ||||
| 2016-09-08 | 2016-09-06 | 4 | LeBel Carl | OTIC | Common Stock | D | 6,3300 | 3.813 | 24 | 25.404 | ||||
| 2016-09-08 | 2016-09-06 | 4 | LeBel Carl | OTIC | Common Stock | D | 6,3300 | 12.133 | 77 | 21.591 | ||||
| 2016-09-08 | 2016-06-01 | 4 | LeBel Carl | OTIC | Common Stock | D | 13,1325 | 275 | 4 | 9.458 | ||||
| 2016-09-08 | 2015-12-01 | 4 | LeBel Carl | OTIC | Common Stock | D | 13,6000 | 263 | 4 | 9.183 | ||||
| 2016-08-04 | 2016-08-02 | 4 | McGill Iain | OTIC | Stock Option (right to buy) | D | 14,20 | 25.000 | 25.000 | |||||
| 2016-06-21 | 2016-06-21 | 4 | Schroeder Theodore R | OTIC | Stock Option (right to buy) | D | 15,20 | 15.000 | 15.000 | |||||
| 2016-06-21 | 2016-06-21 | 4 | CAPPS VICKIE L | OTIC | Stock Option (right to buy) | D | 15,20 | 15.000 | 15.000 | |||||
| 2016-06-21 | 2016-06-21 | 4 | Lichter Jay | OTIC | Stock Option (right to buy) | D | 15,20 | 15.000 | 15.000 | |||||
| 2016-06-21 | 2016-06-21 | 4 | MORROW GEORGE J | OTIC | Stock Option (right to buy) | D | 15,20 | 15.000 | 15.000 | |||||
| 2016-06-21 | 2016-06-21 | 4 | Preston Heather | OTIC | Stock Option (right to buy) | D | 15,20 | 15.000 | 15.000 | |||||
| 2016-06-21 | 2016-06-21 | 4 | Khuong Chau Quang | OTIC | Stock Option (right to buy) | D | 15,20 | 15.000 | 15.000 | |||||
| 2016-03-03 | 2016-03-01 | 4 | LeBel Carl | OTIC | Employee Stock Option (right to buy) | D | 14,44 | 35.000 | 35.000 | |||||
| 2016-03-03 | 2016-03-01 | 4 | LOUMEAU ERIC J | OTIC | Employee Stock Option (right to buy) | D | 14,44 | 70.000 | 70.000 | |||||
| 2016-03-03 | 2016-03-01 | 4 | Savel Robert Michael II | OTIC | Employee Stock Option (right to buy) | D | 14,44 | 55.000 | 55.000 | |||||
| 2016-03-03 | 2016-03-01 | 4 | Yost Anthony J | OTIC | Employee Stock Option (right to buy) | D | 14,44 | 75.000 | 75.000 | |||||
| 2016-03-03 | 2016-03-01 | 4 | Cayer Paul E | OTIC | Employee Stock Option (right to buy) | D | 14,44 | 70.000 | 70.000 | |||||
| 2016-03-03 | 2016-03-01 | 4 | Weber David Allen | OTIC | Employee Stock Option (right to buy) | D | 14,44 | 230.000 | 230.000 | |||||
| 2016-03-03 | 2016-03-01 | 4 | Hakanson Dean | OTIC | Employee Stock Option (right to buy) | D | 14,44 | 100.000 | 100.000 | |||||
| 2015-12-22 | 2015-12-21 | 4 | LeBel Carl | OTIC | Employee stock option (right to buy) | D | 3,17 | -4.674 | 25.189 | |||||
| 2015-12-22 | 2015-12-21 | 4 | LeBel Carl | OTIC | Employee stock option (right to buy) | D | 6,33 | -16.576 | 51.380 | |||||
| 2015-12-22 | 2015-12-21 | 4 | LeBel Carl | OTIC | Common Stock | D | 28,3778 | -8.061 | -229 | 8.920 | ||||
| 2015-12-22 | 2015-12-21 | 4 | LeBel Carl | OTIC | Common Stock | D | 27,8318 | -13.189 | -367 | 16.981 | ||||
| 2015-12-22 | 2015-12-21 | 4 | LeBel Carl | OTIC | Common Stock | D | 3,1700 | 4.674 | 15 | 30.170 | ||||
| 2015-12-22 | 2015-12-21 | 4 | LeBel Carl | OTIC | Common Stock | D | 6,3300 | 16.576 | 105 | 25.496 | ||||
| 2015-12-18 | 2015-12-17 | 4 | Cayer Paul E | OTIC | Employee stock option (right to buy) | D | 6,33 | -3.000 | 77.492 | |||||
| 2015-12-18 | 2015-12-17 | 4 | Cayer Paul E | OTIC | Common Stock | D | 30,1850 | -300 | -9 | 9.610 | ||||
| 2015-12-18 | 2015-12-17 | 4 | Cayer Paul E | OTIC | Common Stock | D | 29,6464 | -2.700 | -80 | 9.910 | ||||
| 2015-12-18 | 2015-12-17 | 4 | Cayer Paul E | OTIC | Common Stock | D | 6,3300 | 3.000 | 19 | 12.610 | ||||
| 2015-12-16 | 2015-12-15 | 4 | Weber David Allen | OTIC | Employee Stock Option (right to buy) | D | 1,76 | -5.208 | 390.149 | |||||
| 2015-12-16 | 2015-12-15 | 4 | Weber David Allen | OTIC | Common Stock | D | 27,2498 | -5.208 | -142 | 17.603 | ||||
| 2015-12-16 | 2015-12-15 | 4 | Weber David Allen | OTIC | Common Stock | D | 1,7600 | 5.208 | 9 | 22.811 | ||||
| 2015-12-16 | 2015-12-14 | 4 | Savel Robert Michael II | OTIC | Employee Stock Option (right to buy) | D | 1,76 | -1.588 | 79.047 | |||||
| 2015-12-16 | 2015-12-14 | 4 | Savel Robert Michael II | OTIC | Employee Stock Option (right to buy) | D | 6,33 | -3.412 | 32.994 | |||||
| 2015-12-16 | 2015-12-14 | 4 | Savel Robert Michael II | OTIC | Common Stock | D | 27,7024 | -100 | -3 | 1.256 | ||||
| 2015-12-16 | 2015-12-14 | 4 | Savel Robert Michael II | OTIC | Common Stock | D | 27,2581 | -1.289 | -35 | 1.356 | ||||
| 2015-12-16 | 2015-12-14 | 4 | Savel Robert Michael II | OTIC | Common Stock | D | 26,1492 | -1.289 | -34 | 2.645 | ||||
| 2015-12-16 | 2015-12-14 | 4 | Savel Robert Michael II | OTIC | Common Stock | D | 25,1350 | -2.322 | -58 | 3.934 | ||||
| 2015-12-16 | 2015-12-14 | 4 | Savel Robert Michael II | OTIC | Common Stock | D | 1,7600 | 1.588 | 3 | 6.256 | ||||
| 2015-12-16 | 2015-12-14 | 4 | Savel Robert Michael II | OTIC | Common Stock | D | 6,3300 | 3.412 | 22 | 4.668 | ||||
| 2015-11-30 | 2015-11-30 | 4 | Khuong Chau Quang See Footnotes | OTIC | Common Stock | I | 29,2200 | -590 | -17 | 1.850.094 | ||||
| 2015-11-30 | 2015-11-30 | 4 | Khuong Chau Quang See Footnotes | OTIC | Common Stock | I | 28,6400 | -2.716 | -78 | 1.850.684 | ||||
| 2015-11-30 | 2015-11-27 | 4 | Khuong Chau Quang See Footnotes | OTIC | Common Stock | I | 28,9700 | -29.000 | -840 | 1.853.400 | ||||
| 2015-11-30 | 2015-11-25 | 4 | Khuong Chau Quang See Footnotes | OTIC | Common Stock | I | 28,9100 | -34.800 | -1.006 | 1.882.400 | ||||
| 2015-11-30 | 2015-11-30 | 4 | ORBIMED ADVISORS LLC See Footnotes | OTIC | Common Stock | I | 29,2200 | -590 | -17 | 1.850.094 | ||||
| 2015-11-30 | 2015-11-30 | 4 | ORBIMED ADVISORS LLC See Footnotes | OTIC | Common Stock | I | 28,6400 | -2.716 | -78 | 1.850.684 | ||||
| 2015-11-30 | 2015-11-27 | 4 | ORBIMED ADVISORS LLC See Footnotes | OTIC | Common Stock | I | 28,9700 | -29.000 | -840 | 1.853.400 | ||||
| 2015-11-30 | 2015-11-25 | 4 | ORBIMED ADVISORS LLC See Footnotes | OTIC | Common Stock | I | 28,9100 | -34.800 | -1.006 | 1.882.400 | ||||
| 2015-11-24 | 2015-11-24 | 4 | Khuong Chau Quang See Footnotes | OTIC | Common Stock | I | 28,7500 | -36.100 | -1.038 | 1.917.200 | ||||
| 2015-11-24 | 2015-11-23 | 4 | Khuong Chau Quang See Footnotes | OTIC | Common Stock | I | 28,4500 | -80.800 | -2.299 | 1.953.300 | ||||
| 2015-11-24 | 2015-11-20 | 4 | Khuong Chau Quang See Footnotes | OTIC | Common Stock | I | 28,5900 | -83.900 | -2.399 | 2.034.100 | ||||
| 2015-11-24 | 2015-11-24 | 4 | ORBIMED ADVISORS LLC See Footnotes | OTIC | Common Stock | I | 28,7500 | -36.100 | -1.038 | 1.917.200 | ||||
| 2015-11-24 | 2015-11-23 | 4 | ORBIMED ADVISORS LLC See Footnotes | OTIC | Common Stock | I | 28,4500 | -80.800 | -2.299 | 1.953.300 | ||||
| 2015-11-24 | 2015-11-20 | 4 | ORBIMED ADVISORS LLC See Footnotes | OTIC | Common Stock | I | 28,5900 | -83.900 | -2.399 | 2.034.100 | ||||
| 2015-11-19 | 2015-11-19 | 4 | Khuong Chau Quang See Footnotes | OTIC | Common Stock | I | 28,6000 | -127.300 | -3.641 | 2.118.000 | ||||
| 2015-11-19 | 2015-11-17 | 4 | Khuong Chau Quang See Footnotes | OTIC | Common Stock | I | 29,0900 | -200 | -6 | 2.245.300 | ||||
| 2015-11-19 | 2015-11-17 | 4 | Khuong Chau Quang See Footnotes | OTIC | Common Stock | I | 28,8000 | -10.898 | -314 | 2.245.500 | ||||
| 2015-11-19 | 2015-11-19 | 4 | ORBIMED ADVISORS LLC See Footnotes | OTIC | Common Stock | I | 28,6000 | -127.300 | -3.641 | 2.118.000 | ||||
| 2015-11-19 | 2015-11-17 | 4 | ORBIMED ADVISORS LLC See Footnotes | OTIC | Common Stock | I | 29,0900 | -200 | -6 | 2.245.300 | ||||
| 2015-11-19 | 2015-11-17 | 4 | ORBIMED ADVISORS LLC See Footnotes | OTIC | Common Stock | I | 28,8000 | -10.898 | -314 | 2.245.500 | ||||
| 2015-11-17 | 2015-11-17 | 4 | Cayer Paul E | OTIC | Employee Stock Option (right to buy) | D | 6,33 | -3.000 | 80.492 | |||||
| 2015-11-17 | 2015-11-17 | 4 | Cayer Paul E | OTIC | Common Stock | D | 28,6858 | -3.000 | -86 | 9.610 | ||||
| 2015-11-17 | 2015-11-17 | 4 | Cayer Paul E | OTIC | Common Stock | D | 6,3300 | 3.000 | 19 | 12.610 | ||||
| 2015-11-17 | 2015-11-16 | 4 | Weber David Allen | OTIC | Employee Stock Option (right to buy) | D | 1,76 | -5.208 | 395.357 | |||||
| 2015-11-17 | 2015-11-16 | 4 | Weber David Allen | OTIC | Common Stock | D | 29,2500 | -100 | -3 | 17.603 | ||||
| 2015-11-17 | 2015-11-16 | 4 | Weber David Allen | OTIC | Common Stock | D | 28,5605 | -5.108 | -146 | 17.703 | ||||
| 2015-11-17 | 2015-11-16 | 4 | Weber David Allen | OTIC | Common Stock | D | 1,7600 | 5.208 | 9 | 22.811 | ||||
| 2015-11-13 | 2015-11-13 | 4 | Weber David Allen | OTIC | Employee Stock Option (right to buy) | D | 1,76 | -10.416 | 400.565 | |||||
| 2015-11-13 | 2015-11-13 | 4 | Weber David Allen | OTIC | Common Stock | D | 30,9500 | -10.416 | -322 | 539 | ||||
| 2015-11-13 | 2015-11-13 | 4 | Weber David Allen | OTIC | Common Stock | D | 1,7600 | 10.416 | 18 | 10.955 | ||||
| 2015-11-12 | 2015-11-11 | 4 | Cayer Paul E | OTIC | Employee Stock Option (right to buy) | D | 6,33 | -1.547 | 83.492 | |||||
| 2015-11-12 | 2015-11-11 | 4 | Cayer Paul E | OTIC | Employee Stock Option (right to buy) | D | 1,76 | -1.453 | 137.088 | |||||
| 2015-11-12 | 2015-11-11 | 4 | Cayer Paul E | OTIC | Common Stock | D | 24,9500 | -3.000 | -75 | 9.610 | ||||
| 2015-11-12 | 2015-11-11 | 4 | Cayer Paul E | OTIC | Common Stock | D | 6,3300 | 1.547 | 10 | 12.610 | ||||
| 2015-11-12 | 2015-11-11 | 4 | Cayer Paul E | OTIC | Conmon Stock | D | 1,7600 | 1.453 | 3 | 11.063 | ||||
| 2015-11-12 | 2015-11-11 | 4 | Weber David Allen | OTIC | Employee Stock Option (right to buy) | D | 1,76 | -5.208 | 410.981 | |||||
| 2015-11-12 | 2015-11-11 | 4 | Weber David Allen | OTIC | Common Stock | D | 24,9500 | -5.208 | -130 | 539 | ||||
| 2015-11-12 | 2015-11-11 | 4 | Weber David Allen | OTIC | Common Stock | D | 1,7600 | 5.208 | 9 | 5.747 | ||||
| 2015-09-22 | 2015-09-21 | 4 | LeBel Carl | OTIC | Employee Stock Option (right to buy) | D | 6,33 | 24,3565 | -17.083 | -416 | 67.956 | |||
| 2015-09-22 | 2015-09-21 | 4 | LeBel Carl | OTIC | Employee Stock Option (right to buy) | D | 1,76 | 24,3565 | -4.167 | -101 | 137.284 | |||
| 2015-09-22 | 2015-09-21 | 4 | LeBel Carl | OTIC | Common Stock | D | 24,3565 | -21.250 | -518 | 8.920 | ||||
| 2015-09-22 | 2015-09-21 | 4 | LeBel Carl | OTIC | Common Stock | D | 6,3300 | 17.083 | 108 | 30.170 | ||||
| 2015-09-22 | 2015-09-21 | 4 | LeBel Carl | OTIC | Common Stock | D | 1,7600 | 4.167 | 7 | 13.087 | ||||
| 2015-09-18 | 2015-09-17 | 4 | Cayer Paul E | OTIC | Employee Stock Option (right to buy) | D | 1,76 | 24,9500 | -3.000 | -75 | 138.541 | |||
| 2015-09-18 | 2015-09-17 | 4 | Cayer Paul E | OTIC | Common Stock | D | 24,9500 | -3.000 | -75 | 9.610 | ||||
| 2015-09-18 | 2015-09-17 | 4 | Cayer Paul E | OTIC | Common Stock | D | 1,7600 | 3.000 | 5 | 12.610 | ||||
| 2015-09-16 | 2015-09-15 | 4 | Weber David Allen | OTIC | Employee Stock Option (right to buy) | D | 1,76 | 24,9500 | -5.216 | -130 | 416.189 | |||
| 2015-09-16 | 2015-09-15 | 4 | Weber David Allen | OTIC | Common Stock | D | 24,9500 | -5.216 | -130 | 539 | ||||
| 2015-09-16 | 2015-09-15 | 4 | Weber David Allen | OTIC | Common Stock | D | 1,7600 | 5.216 | 9 | 5.755 | ||||
| 2015-09-15 | 2015-09-14 | 4 | Savel Robert Michael II | OTIC | Employee Stock Option (right to buy) | D | 6,33 | 6,3300 | -3.413 | -22 | 36.406 | |||
| 2015-09-15 | 2015-09-14 | 4 | Savel Robert Michael II | OTIC | Employee Stock Option (right to buy) | D | 1,76 | 1,7600 | -1.587 | -3 | 80.635 | |||
| 2015-09-15 | 2015-09-14 | 4 | Savel Robert Michael II | OTIC | Common Stock | D | 23,9793 | -5.000 | -120 | 1.256 | ||||
| 2015-09-15 | 2015-09-14 | 4 | Savel Robert Michael II | OTIC | Common Stock | D | 6,3300 | 3.413 | 22 | 6.256 | ||||
| 2015-09-15 | 2015-09-14 | 4 | Savel Robert Michael II | OTIC | Common Stock | D | 1,7600 | 1.587 | 3 | 2.843 | ||||
| 2015-09-01 | 2015-08-28 | 4 | Schroeder Theodore R | OTIC | Stock Option (right to buy) | D | 23,50 | 25.000 | 25.000 | |||||
| 2015-06-22 | 2015-06-19 | 4 | CAPPS VICKIE L | OTIC | Stock Option (right to buy) | D | 22,12 | 15.000 | 15.000 | |||||
| 2015-06-22 | 2015-06-19 | 4 | Lichter Jay | OTIC | 06/19/2015 | D | 22,12 | 15.000 | 15.000 | |||||
| 2015-06-22 | 2015-06-19 | 4 | Preston Heather | OTIC | Stock Option (right to buy) | D | 22,12 | 15.000 | 15.000 | |||||
| 2015-06-22 | 2015-06-19 | 4 | Khuong Chau Quang | OTIC | Stock Option (right to buy) | D | 22,12 | 15.000 | 15.000 | |||||
| 2015-06-17 | 2015-06-15 | 4 | Savel Robert Michael II | OTIC | Employee Stock Option (right to buy) | D | 6,33 | 6,3300 | -14.788 | -94 | 39.819 | |||
| 2015-06-17 | 2015-06-15 | 4 | Savel Robert Michael II | OTIC | Employee Stock Option (right to buy) | D | 1,76 | 1,7600 | -10.212 | -18 | 82.222 | |||
| 2015-06-17 | 2015-06-15 | 4 | Savel Robert Michael II | OTIC | Common Stock | D | 23,7314 | -25.000 | -593 | 1.256 | ||||
| 2015-06-17 | 2015-06-15 | 4 | Savel Robert Michael II | OTIC | Common Stock | D | 6,3300 | 14.788 | 94 | 26.256 | ||||
| 2015-06-17 | 2015-06-15 | 4 | Savel Robert Michael II | OTIC | Common Stock | D | 1,7600 | 10.212 | 18 | 11.468 | ||||
| 2015-06-02 | 2015-06-01 | 4 | LeBel Carl | OTIC | Common Stock | D | 13,6000 | 389 | 5 | 389 | ||||
| 2015-06-02 | 2015-06-01 | 4 | Savel Robert Michael II | OTIC | Common Stock | D | 13,6000 | 1.256 | 17 | 1.256 | ||||
| 2015-06-02 | 2015-06-01 | 4 | Cayer Paul E | OTIC | Common Stock | D | 13,6000 | 2.500 | 34 | 2.500 | ||||
| 2015-06-02 | 2015-06-01 | 4 | Weber David Allen | OTIC | Common Stock | D | 13,6000 | 539 | 7 | 539 | ||||
| 2015-05-29 | 2015-05-28 | 4 | DOVEY BRIAN H By One Palmer Square Associates VIII, LLC | OTIC | Common Stock | I | 32.745 | 32.745 | ||||||
| 2015-05-29 | 2015-05-28 | 4 | DOVEY BRIAN H By Domain Partners VIII, L.P. | OTIC | Common Stock | I | -250.000 | 1.329.323 | ||||||
| 2015-05-27 | 2015-05-22 | 4 | CAPPS VICKIE L Held by spouse | OTIC | Common Stock | I | 24,3503 | 1.600 | 39 | 1.600 | ||||
| 2015-05-27 | 2015-05-22 | 4 | CAPPS VICKIE L | OTIC | Common Stock | D | 24,3552 | 3.400 | 83 | 3.400 | ||||
| 2015-05-18 | 3 | LOUMEAU ERIC J | OTIC | No securities are beneficially owned. | D | 0 | ||||||||
| 2015-05-18 | 2015-05-15 | 4 | LOUMEAU ERIC J | OTIC | Employee Stock Option (right to buy) | D | 31,59 | 31,5900 | 100.000 | 3.159 | 100.000 | |||
| 2015-04-30 | 3 | MORROW GEORGE J | OTIC | No securities are beneficially owned. | D | 0 | ||||||||
| 2015-04-30 | 2015-04-28 | 4 | MORROW GEORGE J | OTIC | Employee Stock Option (right to buy) | D | 27,58 | 27,5800 | 25.000 | 690 | 25.000 | |||
| 2015-04-03 | 2015-04-01 | 4 | Hakanson Dean | OTIC | Employee Stock Option (right to buy) | D | 34,60 | 34,6000 | 115.000 | 3.979 | 115.000 | |||
| 2015-04-02 | 3 | Hakanson Dean | OTIC | No securities are beneficially owned. | D | 0 | ||||||||
| 2014-12-12 | 2014-12-11 | 4 | Cayer Paul E | OTIC | Employee Stock Option (right to buy) | D | 34,12 | 60.000 | 60.000 | |||||
| 2014-12-12 | 2014-12-11 | 4 | LeBel Carl | OTIC | Employee Stock Option (right to buy) | D | 34,12 | 40.000 | 40.000 | |||||
| 2014-12-12 | 2014-12-11 | 4 | Weber David Allen | OTIC | Employee Stock Option (right to buy) | D | 34,12 | 130.000 | 130.000 | |||||
| 2014-12-12 | 2014-12-11 | 4 | Savel Robert Michael II | OTIC | Employee Stock Option (right to buy) | D | 34,12 | 30.000 | 30.000 | |||||
| 2014-10-21 | 2014-10-20 | 4 | Yost Anthony J | OTIC | Employee Stock Option (right to buy) | D | 22,74 | 22,7400 | 180.000 | 4.093 | 180.000 | |||
| 2014-10-21 | 3 | Yost Anthony J | OTIC | No securities are beneficially owned. | D | 0 | ||||||||
| 2014-08-21 | 2014-08-19 | 4 | Novo A/S | OTIC | Common Stock | D | 15,4962 | 15.690 | 243 | 2.175.025 | ||||
| 2014-08-19 | 2014-08-18 | 4 | Novo A/S | OTIC | Series D Preferred Stock | D | -348.041 | 0 | ||||||
| 2014-08-19 | 2014-08-18 | 4 | Novo A/S | OTIC | Series C Preferred Stock | D | -1.131.436 | 0 | ||||||
| 2014-08-19 | 2014-08-18 | 4 | Novo A/S | OTIC | Series B Preferred Stock | D | -439.724 | 0 | ||||||
| 2014-08-19 | 2014-08-18 | 4 | Novo A/S | OTIC | Series C Preferred Stock Warrant (Right to Buy) | D | -31.854 | 0 | ||||||
| 2014-08-19 | 2014-08-18 | 4 | Novo A/S | OTIC | Series C Preferred Stock Warrant (Right to Buy) | D | -36.405 | 0 | ||||||
| 2014-08-19 | 2014-08-18 | 4 | Novo A/S | OTIC | Common Stock | D | 16,0000 | 171.875 | 2.750 | 2.159.335 | ||||
| 2014-08-19 | 2014-08-18 | 4 | Novo A/S | OTIC | Common Stock | D | 1.919.201 | 1.987.460 | ||||||
| 2014-08-19 | 2014-08-18 | 4 | Novo A/S | OTIC | Common Stock | D | 31.854 | 68.259 | ||||||
| 2014-08-19 | 2014-08-18 | 4 | Novo A/S | OTIC | Common Stock | D | 36.405 | 36.405 | ||||||
| 2014-08-19 | 2014-08-18 | 4 | Lichter Jay See footnotes | OTIC | Common Stock Warrant (right to buy) | I | 8,79 | -91.011 | 0 | |||||
| 2014-08-19 | 2014-08-18 | 4 | Lichter Jay | OTIC | Common Stock Warrant (right to buy) | I | 8,79 | 91.011 | 91.011 | |||||
| 2014-08-19 | 2014-08-18 | 4 | Lichter Jay | OTIC | Series C Preferred Stock Warrant (right to buy) | I | 8,79 | -91.011 | 0 | |||||
| 2014-08-19 | 2014-08-18 | 4 | Lichter Jay | OTIC | Common Stock Warrant (right to buy) | I | 14,18 | 14.106 | 14.106 | |||||
| 2014-08-19 | 2014-08-18 | 4 | Lichter Jay | OTIC | Common Stock Warrant (right to buy) | I | 14,18 | 14.106 | 14.106 | |||||
| 2014-08-19 | 2014-08-18 | 4 | Lichter Jay | OTIC | Series A Preferred Stock Warrant (right to buy) | I | 31,09 | -6.432 | 0 | |||||
| 2014-08-19 | 2014-08-18 | 4 | Lichter Jay | OTIC | Series A Preferred Stock Warrant (right to buy) | I | 31,09 | -6.432 | 0 | |||||
| 2014-08-19 | 2014-08-18 | 4 | Lichter Jay | OTIC | Common Stock Warrant (right to buy) | I | 14,18 | 14.106 | 14.106 | |||||
| 2014-08-19 | 2014-08-18 | 4 | Lichter Jay | OTIC | Series A Preferred Stock Warrant (right to buy) | I | 31,09 | -6.432 | 0 | |||||
| 2014-08-19 | 2014-08-18 | 4 | Lichter Jay | OTIC | Common Stock Warrant (right to buy) | I | 14,18 | 14.106 | 14.106 | |||||
| 2014-08-19 | 2014-08-18 | 4 | Lichter Jay | OTIC | Series A Preferred Stock Warrant (right to buy) | I | 31,09 | -6.432 | 0 | |||||
| 2014-08-19 | 2014-08-18 | 4 | Lichter Jay | OTIC | Common Stock Warrant (right to buy) | I | 14,18 | 14.106 | 14.106 | |||||
| 2014-08-19 | 2014-08-18 | 4 | Lichter Jay | OTIC | Series A Preferred Stock Warrant (right to buy) | I | 31,09 | -6.432 | 0 | |||||
| 2014-08-19 | 2014-08-18 | 4 | Lichter Jay | OTIC | Common Stock Warrant (right to buy) | I | 14,18 | 14.106 | 14.106 | |||||
| 2014-08-19 | 2014-08-18 | 4 | Lichter Jay | OTIC | Series A Preferred Stock Warrant (right to buy) | I | 31,09 | -6.432 | 0 | |||||
| 2014-08-19 | 2014-08-18 | 4 | Lichter Jay | OTIC | Common Stock Warrant (right to buy) | I | 14,18 | 14.106 | 14.106 | |||||
| 2014-08-19 | 2014-08-18 | 4 | Lichter Jay | OTIC | Series A Preferred Stock Warrant (right to buy) | I | 31,09 | -6.432 | 0 | |||||
| 2014-08-19 | 2014-08-18 | 4 | Lichter Jay | OTIC | Common Stock Warrant (right to buy) | I | 14,18 | 14.106 | 14.106 | |||||
| 2014-08-19 | 2014-08-18 | 4 | Lichter Jay | OTIC | Series A Preferred Stock Warrant (right to buy) | I | 31,09 | -6.432 | 0 | |||||
| 2014-08-19 | 2014-08-18 | 4 | Lichter Jay | OTIC | Common Stock Warrant (right to buy) | I | 14,18 | 14.106 | 14.106 | |||||
| 2014-08-19 | 2014-08-18 | 4 | Lichter Jay | OTIC | Series A Preferred Stock Warrant (right to buy) | I | 31,09 | -6.432 | 0 | |||||
| 2014-08-19 | 2014-08-18 | 4 | Lichter Jay | OTIC | Common Stock Warrant (right to buy) | I | 14,18 | 14.106 | 14.106 | |||||
| 2014-08-19 | 2014-08-18 | 4 | Lichter Jay | OTIC | Series A Preferred Stock Warrant (right to buy) | I | 31,09 | -6.432 | 0 | |||||
| 2014-08-19 | 2014-08-18 | 4 | Lichter Jay | OTIC | Series D Preferred Stock | I | -136.770 | 0 | ||||||
| 2014-08-19 | 2014-08-18 | 4 | Lichter Jay | OTIC | Series C Preferred Stock | I | -568.828 | 0 | ||||||
| 2014-08-19 | 2014-08-18 | 4 | Lichter Jay | OTIC | Series C Preferred Stock | I | -484.691 | 0 | ||||||
| 2014-08-19 | 2014-08-18 | 4 | Lichter Jay | OTIC | Series B Preferred Stock | I | -175.889 | 0 | ||||||
| 2014-08-19 | 2014-08-18 | 4 | Lichter Jay | OTIC | Series A Preferred Stock | I | -337.432 | 0 | ||||||
| 2014-08-19 | 2014-08-18 | 4 | Lichter Jay See footnotes | OTIC | Common Stock | I | 16,0000 | 109.375 | 1.750 | 814.973 | ||||
| 2014-08-19 | 2014-08-18 | 4 | Lichter Jay | OTIC | Common Stock | I | 705.598 | 705.598 | ||||||
| 2014-08-19 | 2014-08-18 | 4 | Lichter Jay See footnotes | OTIC | Common Stock | I | 16,0000 | -50.001 | -800 | 1.450.179 | ||||
| 2014-08-19 | 2014-08-18 | 4 | Lichter Jay See footnotes | OTIC | Common Stock | I | 8,7900 | 91.011 | 800 | 1.500.180 | ||||
| 2014-08-19 | 2014-08-18 | 4 | Lichter Jay | OTIC | Common Stock | I | 660.580 | 1.409.169 | ||||||
| 2014-08-19 | 2014-08-18 | 4 | Lichter Jay | OTIC | Common Stock | I | 740.057 | 748.589 | ||||||
| 2014-08-19 | 2014-08-18 | 4 | CAPPS VICKIE L | OTIC | Series D Convertible Preferred Stock | D | -20.912 | 0 | ||||||
| 2014-08-19 | 2014-08-18 | 4 | CAPPS VICKIE L | OTIC | Common Stock | D | 20.912 | 42.242 | ||||||
| 2014-08-19 | 2014-08-18 | 4 | MCKEARN JOHN P See footnotes | OTIC | Common Stock Warrant (right to buy) | I | 8,79 | -4.536 | 0 | |||||
| 2014-08-19 | 2014-08-18 | 4 | MCKEARN JOHN P See footnotes | OTIC | Common Stock Warrant (right to buy) | I | 8,79 | 4.536 | 4.536 | |||||
| 2014-08-19 | 2014-08-18 | 4 | MCKEARN JOHN P See footnotes | OTIC | Series C Preferred Stock Warrant (right to buy) | I | 8,79 | -4.536 | 0 | |||||
| 2014-08-19 | 2014-08-18 | 4 | MCKEARN JOHN P See footnotes | OTIC | Common Stock Warrant (right to buy) | I | 8,79 | -5.184 | 0 | |||||
| 2014-08-19 | 2014-08-18 | 4 | MCKEARN JOHN P See footnotes | OTIC | Common Stock Warrant (right to buy) | I | 8,79 | 5.184 | 5.184 | |||||
| 2014-08-19 | 2014-08-18 | 4 | MCKEARN JOHN P See footnotes | OTIC | Series C Preferred Stock Warrant (right to buy) | I | 8,79 | -5.184 | 0 | |||||
| 2014-08-19 | 2014-08-18 | 4 | MCKEARN JOHN P See footnotes | OTIC | Series D Preferred Stock | I | -38.325 | 0 | ||||||
| 2014-08-19 | 2014-08-18 | 4 | MCKEARN JOHN P See footnotes | OTIC | Series C Preferred Stock | I | -130.741 | 0 | ||||||
| 2014-08-19 | 2014-08-18 | 4 | MCKEARN JOHN P See footnotes | OTIC | Series B Preferred Stock | I | -42.265 | 0 | ||||||
| 2014-08-19 | 2014-08-18 | 4 | MCKEARN JOHN P See footnotes | OTIC | Common Stock Warrant (right to buy) | I | 8,79 | -16.700 | 0 | |||||
| 2014-08-19 | 2014-08-18 | 4 | MCKEARN JOHN P See footnotes | OTIC | Common Stock Warrant (right to buy) | I | 8,79 | 16.700 | 16.700 | |||||
| 2014-08-19 | 2014-08-18 | 4 | MCKEARN JOHN P See footnotes | OTIC | Series C Preferred Stock Warrant (right to buy) | I | 8,79 | -16.700 | 0 | |||||
| 2014-08-19 | 2014-08-18 | 4 | MCKEARN JOHN P See footnotes | OTIC | Common Stock Warrant (right to buy) | I | 8,79 | -19.085 | 0 | |||||
| 2014-08-19 | 2014-08-18 | 4 | MCKEARN JOHN P See footnotes | OTIC | Common Stock Warrant (right to buy) | I | 8,79 | 19.085 | 19.085 | |||||
| 2014-08-19 | 2014-08-18 | 4 | MCKEARN JOHN P See footnotes | OTIC | Series C Preferred Stock Warrant (right to buy) | I | 8,79 | -19.085 | 0 | |||||
| 2014-08-19 | 2014-08-18 | 4 | MCKEARN JOHN P See footnotes | OTIC | Series D Preferred Stock | I | -141.101 | 0 | ||||||
| 2014-08-19 | 2014-08-18 | 4 | MCKEARN JOHN P See footnotes | OTIC | Series C Preferred Stock | I | -481.342 | 0 | ||||||
| 2014-08-19 | 2014-08-18 | 4 | MCKEARN JOHN P See footnotes | OTIC | Series B Preferred Stock | I | -155.609 | 0 | ||||||
| 2014-08-19 | 2014-08-18 | 4 | MCKEARN JOHN P See footnotes | OTIC | Common Stock | I | 8,7900 | -5.340 | -47 | 215.711 | ||||
| 2014-08-19 | 2014-08-18 | 4 | MCKEARN JOHN P See footnotes | OTIC | Common Stock | I | 8,7900 | 9.720 | 85 | 221.051 | ||||
| 2014-08-19 | 2014-08-18 | 4 | MCKEARN JOHN P See footnotes | OTIC | Common Stock | I | 211.331 | 211.331 | ||||||
| 2014-08-19 | 2014-08-18 | 4 | MCKEARN JOHN P See footnotes | OTIC | Common Stock | I | 8,7900 | -19.660 | -173 | 794.177 | ||||
| 2014-08-19 | 2014-08-18 | 4 | MCKEARN JOHN P See footnotes | OTIC | Common Stock | I | 8,7900 | 35.785 | 315 | 813.837 | ||||
| 2014-08-19 | 2014-08-18 | 4 | MCKEARN JOHN P See footnotes | OTIC | Common Stock | I | 778.052 | 778.052 | ||||||
| 2014-08-19 | 2014-08-18 | 4 | ORBIMED ADVISORS LLC See footnotes | OTIC | Series D Preferred Stock | I | -378.039 | 0 | ||||||
| 2014-08-19 | 2014-08-18 | 4 | ORBIMED ADVISORS LLC See footnotes | OTIC | Series C Preferred Stock | I | -1.706.484 | 0 | ||||||
| 2014-08-19 | 2014-08-18 | 4 | ORBIMED ADVISORS LLC See footnotes | OTIC | Common Stock | I | 16,0000 | 171.875 | 2.750 | 2.256.398 | ||||
| 2014-08-19 | 2014-08-18 | 4 | ORBIMED ADVISORS LLC See footnotes | OTIC | Common Stock | I | 2.084.523 | 2.084.523 | ||||||
| 2014-08-19 | 2014-08-18 | 4 | Avalon Ventures VIII LP | OTIC | Common Stock Warrant (right to buy) | D | 8,79 | -91.011 | 0 | |||||
| 2014-08-19 | 2014-08-18 | 4 | Avalon Ventures VIII LP | OTIC | Common Stock Warrant (right to buy) | D | 8,79 | 91.011 | 91.011 | |||||
| 2014-08-19 | 2014-08-18 | 4 | Avalon Ventures VIII LP | OTIC | Series C Preferred Stock Warrant (right to buy) | D | 8,79 | -91.011 | 0 | |||||
| 2014-08-19 | 2014-08-18 | 4 | Avalon Ventures VIII LP | OTIC | Common Stock Warrant (right to buy) | D | 14,18 | 14.106 | 14.106 | |||||
| 2014-08-19 | 2014-08-18 | 4 | Avalon Ventures VIII LP | OTIC | Common Stock Warrant (right to buy) | D | 14,18 | 14.106 | 14.106 | |||||
| 2014-08-19 | 2014-08-18 | 4 | Avalon Ventures VIII LP | OTIC | Series A Preferred Stock Warrant (right to buy) | D | 31,09 | -6.432 | 0 | |||||
| 2014-08-19 | 2014-08-18 | 4 | Avalon Ventures VIII LP | OTIC | Series A Preferred Stock Warrant (right to buy) | D | 31,09 | -6.432 | 0 | |||||
| 2014-08-19 | 2014-08-18 | 4 | Avalon Ventures VIII LP | OTIC | Common Stock Warrant (right to buy) | D | 14,18 | 14.106 | 14.106 | |||||
| 2014-08-19 | 2014-08-18 | 4 | Avalon Ventures VIII LP | OTIC | Series A Preferred Stock Warrant (right to buy) | D | 31,09 | -6.432 | 0 | |||||
| 2014-08-19 | 2014-08-18 | 4 | Avalon Ventures VIII LP | OTIC | Common Stock Warrant (right to buy) | D | 14,18 | 14.106 | 14.106 | |||||
| 2014-08-19 | 2014-08-18 | 4 | Avalon Ventures VIII LP | OTIC | Series A Preferred Stock Warrant (right to buy) | D | 31,09 | -6.432 | 0 | |||||
| 2014-08-19 | 2014-08-18 | 4 | Avalon Ventures VIII LP | OTIC | Common Stock Warrant (right to buy) | D | 14,18 | 14.106 | 14.106 | |||||
| 2014-08-19 | 2014-08-18 | 4 | Avalon Ventures VIII LP | OTIC | Series A Preferred Stock Warrant (right to buy) | D | 31,09 | -6.432 | 0 | |||||
| 2014-08-19 | 2014-08-18 | 4 | Avalon Ventures VIII LP | OTIC | Common Stock Warrant (right to buy) | D | 14,18 | 14.106 | 14.106 | |||||
| 2014-08-19 | 2014-08-18 | 4 | Avalon Ventures VIII LP | OTIC | Series A Preferred Stock Warrant (right to buy) | D | 31,09 | -6.432 | 0 | |||||
| 2014-08-19 | 2014-08-18 | 4 | Avalon Ventures VIII LP | OTIC | Common Stock Warrant (right to buy) | D | 14,18 | 14.106 | 14.106 | |||||
| 2014-08-19 | 2014-08-18 | 4 | Avalon Ventures VIII LP | OTIC | Series A Preferred Stock Warrant (right to buy) | D | 31,09 | -6.432 | 0 | |||||
| 2014-08-19 | 2014-08-18 | 4 | Avalon Ventures VIII LP | OTIC | Common Stock Warrant (right to buy) | D | 14,18 | 14.106 | 14.106 | |||||
| 2014-08-19 | 2014-08-18 | 4 | Avalon Ventures VIII LP | OTIC | Series A Preferred Stock Warrant (right to buy) | D | 31,09 | -6.432 | 0 | |||||
| 2014-08-19 | 2014-08-18 | 4 | Avalon Ventures VIII LP | OTIC | Common Stock Warrant (right to buy) | D | 14,18 | 14.106 | 14.106 | |||||
| 2014-08-19 | 2014-08-18 | 4 | Avalon Ventures VIII LP | OTIC | Series A Preferred Stock Warrant (right to buy) | D | 31,09 | -6.432 | 0 | |||||
| 2014-08-19 | 2014-08-18 | 4 | Avalon Ventures VIII LP | OTIC | Common Stock Warrant (right to buy) | D | 14,18 | 14.106 | 14.106 | |||||
| 2014-08-19 | 2014-08-18 | 4 | Avalon Ventures VIII LP | OTIC | Series A Preferred Stock Warrant (right to buy) | D | 31,09 | -6.432 | 0 | |||||
| 2014-08-19 | 2014-08-18 | 4 | Avalon Ventures VIII LP | OTIC | Series D Preferred Stock | I | -136.770 | 0 | ||||||
| 2014-08-19 | 2014-08-18 | 4 | Avalon Ventures VIII LP | OTIC | Series C Preferred Stock | I | -568.828 | 0 | ||||||
| 2014-08-19 | 2014-08-18 | 4 | Avalon Ventures VIII LP | OTIC | Series C Preferred Stock | D | -484.691 | 0 | ||||||
| 2014-08-19 | 2014-08-18 | 4 | Avalon Ventures VIII LP | OTIC | Series B Preferred Stock | D | -175.889 | 0 | ||||||
| 2014-08-19 | 2014-08-18 | 4 | Avalon Ventures VIII LP | OTIC | Series A Preferred Stock | D | -337.432 | 0 | ||||||
| 2014-08-19 | 2014-08-18 | 4 | Avalon Ventures VIII LP See footnotes | OTIC | Common Stock | I | 16,0000 | 109.375 | 1.750 | 814.973 | ||||
| 2014-08-19 | 2014-08-18 | 4 | Avalon Ventures VIII LP | OTIC | Common Stock | I | 705.598 | 705.598 | ||||||
| 2014-08-19 | 2014-08-18 | 4 | Avalon Ventures VIII LP | OTIC | Common Stock | D | 16,0000 | -50.001 | -800 | 1.450.179 | ||||
| 2014-08-19 | 2014-08-18 | 4 | Avalon Ventures VIII LP | OTIC | Common Stock | D | 8,7900 | 91.011 | 800 | 1.500.180 | ||||
| 2014-08-19 | 2014-08-18 | 4 | Avalon Ventures VIII LP | OTIC | Common Stock | D | 660.580 | 1.409.169 | ||||||
| 2014-08-19 | 2014-08-18 | 4 | Avalon Ventures VIII LP | OTIC | Common Stock | D | 740.057 | 748.589 | ||||||
| 2014-08-19 | 2014-08-18 | 4 | Khuong Chau Quang See footnotes | OTIC | Series D Preferred Stock | I | -378.039 | 0 | ||||||
| 2014-08-19 | 2014-08-18 | 4 | Khuong Chau Quang See footnotes | OTIC | Series C Preferred Stock | I | -1.706.484 | 0 | ||||||
| 2014-08-19 | 2014-08-18 | 4 | Khuong Chau Quang See footnotes | OTIC | Common Stock | I | 16,0000 | 171.875 | 2.750 | 2.256.398 | ||||
| 2014-08-19 | 2014-08-18 | 4 | Khuong Chau Quang See footnotes | OTIC | Common Stock | I | 2.084.523 | 2.084.523 | ||||||
| 2014-08-19 | 2014-08-18 | 4 | Weber David Allen | OTIC | Common Stock Warrant (right to buy) | I | 8,79 | -113 | 0 | |||||
| 2014-08-19 | 2014-08-18 | 4 | Weber David Allen | OTIC | Common Stock Warrant (right to buy) | I | 8,79 | 113 | 113 | |||||
| 2014-08-19 | 2014-08-18 | 4 | Weber David Allen | OTIC | Series C Preferred Stock Warrant (right to buy) | I | 8,79 | -113 | 0 | |||||
| 2014-08-19 | 2014-08-18 | 4 | Weber David Allen | OTIC | Series D Preferred Stock | I | -1.254 | 0 | ||||||
| 2014-08-19 | 2014-08-18 | 4 | Weber David Allen | OTIC | Series C Preferred Stock | I | -3.445 | 0 | ||||||
| 2014-08-19 | 2014-08-18 | 4 | Weber David Allen See footnotes | OTIC | Common Stock | I | 8,7900 | 113 | 1 | 4.812 | ||||
| 2014-08-19 | 2014-08-18 | 4 | Weber David Allen | OTIC | Common Stock | I | 4.699 | 4.699 | ||||||
| 2014-08-19 | 2014-08-18 | 4 | TPG Group Holdings (SBS) Advisors, Inc. See Explanation of Responses | OTIC | Series D Preferred Stock | I | -348.041 | 0 | ||||||
| 2014-08-19 | 2014-08-18 | 4 | TPG Group Holdings (SBS) Advisors, Inc. See Explanation of Responses | OTIC | Series C Preferred Stock | I | -1.199.695 | 0 | ||||||
| 2014-08-19 | 2014-08-18 | 4 | TPG Group Holdings (SBS) Advisors, Inc. See Explanation of Responses | OTIC | Series B Preferred Stock | I | -439.724 | 0 | ||||||
| 2014-08-19 | 2014-08-18 | 4 | TPG Group Holdings (SBS) Advisors, Inc. See Explanation of Responses | OTIC | Series C Preferred Stock | I | 68.259 | 1.199.695 | ||||||
| 2014-08-19 | 2014-08-18 | 4 | TPG Group Holdings (SBS) Advisors, Inc. See Explanation of Responses | OTIC | Warrant to Purchase Shares of Preferred Stock | I | -68.259 | 0 | ||||||
| 2014-08-19 | 2014-08-18 | 4 | TPG Group Holdings (SBS) Advisors, Inc. See Explanation of Responses | OTIC | Common Stock | I | 171.875 | 2.159.335 | ||||||
| 2014-08-19 | 2014-08-18 | 4 | TPG Group Holdings (SBS) Advisors, Inc. See Explanation of Responses | OTIC | Common Stock | I | 1.987.460 | 1.987.460 | ||||||
| 2014-08-18 | 2014-08-18 | 4 | Domain Partners VIII, L.P. | OTIC | Series C Preferred Stock Warrant (Right to Buy) | D | 8,79 | -67.755 | 0 | |||||
| 2014-08-18 | 2014-08-18 | 4 | Domain Partners VIII, L.P. | OTIC | Series D Preferred Stock | D | -186.828 | 0 | ||||||
| 2014-08-18 | 2014-08-18 | 4 | Domain Partners VIII, L.P. | OTIC | Series C Preferred Stock | D | -925.479 | 0 | ||||||
| 2014-08-18 | 2014-08-18 | 4 | Domain Partners VIII, L.P. | OTIC | Series B Preferred Stock | D | -436.485 | 0 | ||||||
| 2014-08-18 | 2014-08-18 | 4 | Domain Partners VIII, L.P. | OTIC | Common Stock | D | 16,0000 | -37.224 | -596 | 1.579.323 | ||||
| 2014-08-18 | 2014-08-18 | 4 | Domain Partners VIII, L.P. | OTIC | Common Stock | D | 8,7900 | 67.755 | 596 | 1.616.547 | ||||
| 2014-08-18 | 2014-08-18 | 4 | Domain Partners VIII, L.P. | OTIC | Common Stock | D | 1.548.792 | 1.548.792 | ||||||
| 2014-08-18 | 2014-08-18 | 4 | DP VIII Associates, L.P. | OTIC | Series C Preferred Stock Warrant (Right to Buy) | D | 8,79 | -502 | 0 | |||||
| 2014-08-18 | 2014-08-18 | 4 | DP VIII Associates, L.P. | OTIC | Series D Preferred Stock | D | -1.386 | 0 | ||||||
| 2014-08-18 | 2014-08-18 | 4 | DP VIII Associates, L.P. | OTIC | Series C Preferred Stock | D | -6.866 | 0 | ||||||
| 2014-08-18 | 2014-08-18 | 4 | DP VIII Associates, L.P. | OTIC | Series B Preferred Stock | D | -3.238 | 0 | ||||||
| 2014-08-18 | 2014-08-18 | 4 | DP VIII Associates, L.P. | OTIC | Common Stock | D | 16,0000 | -277 | -4 | 11.715 | ||||
| 2014-08-18 | 2014-08-18 | 4 | DP VIII Associates, L.P. | OTIC | Common Stock | D | 8,7900 | 502 | 4 | 11.992 | ||||
| 2014-08-18 | 2014-08-18 | 4 | DP VIII Associates, L.P. | OTIC | Common Stock | D | 11.490 | 11.490 | ||||||
| 2014-08-12 | 3 | Lichter Jay | OTIC | Common Stock | I | 17.064 | ||||||||
| 2014-08-12 | 3 | Lichter Jay | OTIC | Common Stock | I | 17.064 | ||||||||
| 2014-08-12 | 3 | LeBel Carl | OTIC | Common Stock | D | 17.062 | ||||||||
| 2014-08-12 | 3 | LeBel Carl | OTIC | Common Stock | D | 17.062 | ||||||||
| 2014-08-12 | 3 | CAPPS VICKIE L | OTIC | Common Stock | D | 42.660 | ||||||||
| 2014-08-12 | 3 | CAPPS VICKIE L | OTIC | Common Stock | D | 42.660 | ||||||||
| 2014-08-12 | 3 | Avalon Ventures X, L.P. | OTIC | Common Stock | I | 17.064 | ||||||||
| 2014-08-12 | 3 | Avalon Ventures X, L.P. | OTIC | Common Stock | I | 17.064 | ||||||||
| 2014-08-12 | 3 | Avalon Ventures X, L.P. | OTIC | Common Stock | I | 17.064 | ||||||||
| 2014-08-12 | 3 | Bisgaard Peter | OTIC | No securities are beneficially owned | D | 0 | ||||||||
| 2014-08-12 | 3 | Preston Heather | OTIC | No securities beneficially owned | D | 0 | ||||||||
| 2014-08-12 | 3 | Cayer Paul E | OTIC | Common Stock | D | 14.220 | ||||||||
| 2014-08-12 | 3 | Cayer Paul E | OTIC | Common Stock | D | 14.220 | ||||||||
| 2014-08-12 | 3 | Weber David Allen | OTIC | Common Stock | D | 34.128 | ||||||||
| 2014-08-12 | 3 | Weber David Allen | OTIC | Common Stock | D | 34.128 |
