| Insider-Aktien | 812.677 shares |
Insider-Stimmungswert
Der Insider-Stimmungswert ermittelt die Unternehmen, die von Unternehmensinsidern gekauft werden.
Es ist das Ergebnis eines ausgeklügelten quantitativen Multifaktormodells, das die Unternehmen mit der höchsten Insiderakkumulation identifiziert. Das Scoring-Modell verwendet eine Kombination aus der Nettozahl der Insiderkäufe der letzten 90 Tage, der Gesamtzahl der gekauften Aktien als Prozentsatz des Streubesitzes und der Gesamtzahl der von Insidern gehaltenen Aktien. Die Zahl reicht von 0 bis 100, wobei höhere Zahlen ein höheres Maß an Insiderkäufen anzeigen als bei anderen Unternehmen und 50 den Durchschnitt darstellt.
Aktualisierungshäufigkeit: Täglich
Führungskräfte-Stimmungswert
Der Führungskräfte-Stimmungswert findet Unternehmen, die von Führungskräften des Unternehmens gekauft werden.
Per Definition sind Führungskräfte des Unternehmens Insider, aber im Gegensatz zu anderen Insidern (10%ige Aktionäre und Vorstandsmitglieder) arbeiten Führungskräfte täglich für das Unternehmen und verwenden beim Handel ihr eigenes Geld. (10%ige Aktionäre und Vorstandsmitglieder sind oft Fondsmanager, die das Geld anderer Leute verwalten.) Daher sind Insider-Geschäfte, die von Führungskräften getätigt werden, viel bedeutender und sollten entsprechend behandelt werden.
Wie der Insider-Stimmungswert ist auch der Führungskräfte-Stimmungswert das Ergebnis eines ausgeklügelten quantitativen Multifaktormodells, das die Unternehmen mit der höchsten Führungskräftekonzentration identifiziert.
Aktualisierungshäufigkeit: Täglich
Wichtige Insider-Kennzahlen
Diese Karte zeigt, wie das Unternehmen bei verschiedenen Insider-Kennzahlen abschneidet. Der Perzentil-Rang zeigt, wie dieses Unternehmen im Vergleich zu anderen Unternehmen auf den US-Märkten abschneidet. Höhere Ränge deuten auf eine bessere Situation hin.
Es ist beispielsweise allgemein anerkannt, dass Insiderkäufe ein positiver Indikator sind, so dass Unternehmen mit mehr Insiderkäufen besser abschneiden würden als Unternehmen mit weniger Insiderkäufen (oder sogar Insiderverkäufen).
Nettoanzahl der Insider, die kaufen (Rang)
N/A
Die Nettoanzahl der Insiderkäufe ist die Gesamtzahl der Insiderkäufe abzüglich der Gesamtzahl der Insiderverkäufe in den letzten 90 Tagen. Der Perzentilrang wird hier angezeigt (Bereich von 0 bis 100%).
Prozent des Streubesitzes von Insidern gekauft (Rang)
N/A
Prozent des von Insidern gekauften Streubesitzes ist die Gesamtzahl der von Insidern gekauften Aktien abzüglich der Gesamtzahl der von Insidern in den letzten 90 Tagen verkauften Aktien, geteilt durch den gesamten Streubesitz und multipliziert mit 100.
Diagramm zum Insiderhandel
Pieris Pharmaceuticals, Inc. Insider-Trades sind in der folgenden Grafik dargestellt. Insider sind leitende Angestellte, Direktoren oder bedeutende Investoren in einem Unternehmen. Im Allgemeinen ist es für Insider illegal, auf der Grundlage von wesentlichen, nicht-öffentlichen Informationen mit Aktien ihrer Unternehmen zu handeln. Das bedeutet nicht, dass es für sie illegal ist, irgendwelche Geschäfte in ihren eigenen Unternehmen zu tätigen. Sie müssen jedoch alle Geschäfte der SEC über ein Formular 4 melden.
Kennzahlen zu Insiderlisten und Rentabilität
Diese Tabelle zeigt die Liste der bekannten Insider und wird automatisch aus den bei der SEC eingereichten Unterlagen erstellt. Zusätzlich zu den Namen, dem letzten Titel und der Bezeichnung als Direktor, leitender Angestellter oder 10%-iger Anteilseigner geben wir die zuletzt veröffentlichten Bestände an. Zusätzlich stellen wir, wenn möglich, die historische Handelsperformance für den Insider zur Verfügung. Die historische Handelsperformance ist ein gewichteter Durchschnitt der Performance tatsächlicher offener Kauftransaktionen, die von dem Insider getätigt wurden. Weitere Informationen zur Berechnung dieses Wertes finden Sie in diesem YouTube-Webinar.
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| Insider | Durchschnittlicher Gewinn (%) | Aktien in Besitz |
Split Angepasst |
|---|
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Erfolgsbilanz der Insiderkäufe - Kurzfristige Gewinnanalyse
In diesem Abschnitt analysieren wir die Rentabilität jedes ungeplanten Insiderkaufs, der auf dem freien Markt in PIRS / Pieris Pharmaceuticals, Inc. getätigt wurde. Diese Analyse hilft zu verstehen, ob der Insider beständig abnormale Renditen erzielt und es sich lohnt, ihm zu folgen. Diese Analyse bezieht sich auf ein Jahr nach jedem Handel, und die Ergebnisse sind theoretisch .
Die folgende Tabelle zeigt die jüngsten Käufe am offenen Markt, die nicht Teil eines automatischen Handelsplans waren.
Bereinigter Preis ist der splitbereinigte Preis. Bereinigte Aktien sind die um den Split bereinigten Aktien.
Erfolgsbilanz von Insiderverkäufen - Kurzfristige Verlustanalyse
In diesem Abschnitt analysieren wir die kurzfristige Verlustvermeidung jedes ungeplanten Insider-Verkaufs auf dem freien Markt in PIRS / Pieris Pharmaceuticals, Inc.. Ein konsistentes Muster der Verlustvermeidung kann darauf hindeuten, dass zukünftige Verkaufstransaktionen Kursrückgänge vorhersagen können. Diese Analyse bezieht sich auf ein Jahr nach jedem Handel, und die Ergebnisse sind theoretisch .
Die folgende Tabelle zeigt die jüngsten Verkäufe am offenen Markt, die nicht Teil eines automatischen Handelsplans waren.
Bereinigter Preis ist der splitbereinigte Preis. Bereinigte Aktien sind die um den Split bereinigten Aktien.
Transaktionshistorie
Klicken Sie auf das Link-Symbol, um den vollständigen Transaktionsverlauf anzuzeigen. Transaktionen, die im Rahmen eines automatischen Handelsplans 10b5-1 gemeldet werden, sind in der Spalte 10b-5 mit einem X gekennzeichnet.
| Datei Datum |
Handel Datum |
Form | Insider | Ticker | Wertpapier-Titel | Code | Direkt | Ausführung Preis |
Einheit Preis |
Eimheiten Verändert |
Wert Geändert (1K) |
Verbleibende Optionen |
Verbleibende Aktien |
|
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2026-05-22 | 2026-05-20 | 4 | Goin Kathleen | PVLA | Common Stock | D | 111,8950 | -48 | -5 | 0 | ||||
| 2026-05-22 | 2026-05-20 | 4 | Goin Kathleen | PVLA | Common Stock | D | 111,2963 | -891 | -99 | 48 | ||||
| 2026-05-22 | 2026-05-20 | 4 | Goin Kathleen | PVLA | Common Stock | D | 110,3464 | -3.363 | -371 | 939 | ||||
| 2026-05-22 | 2026-05-20 | 4 | Goin Kathleen | PVLA | Common Stock | D | 9,0800 | 2.148 | 20 | 4.302 | ||||
| 2026-05-22 | 2026-05-20 | 4 | Goin Kathleen | PVLA | Common Stock | D | 7,1400 | 2.154 | 15 | 2.154 | ||||
| 2026-04-17 | 2026-04-15 | 4 | Goin Kathleen | PVLA | Common Stock | D | 130,3300 | -100 | -13 | 0 | ||||
| 2026-04-17 | 2026-04-15 | 4 | Goin Kathleen | PVLA | Common Stock | D | 129,1692 | -639 | -83 | 100 | ||||
| 2026-04-17 | 2026-04-15 | 4 | Goin Kathleen | PVLA | Common Stock | D | 128,2349 | -561 | -72 | 739 | ||||
| 2026-04-17 | 2026-04-15 | 4 | Goin Kathleen | PVLA | Common Stock | D | 127,1254 | -1.500 | -191 | 1.300 | ||||
| 2026-04-17 | 2026-04-15 | 4 | Goin Kathleen | PVLA | Common Stock | D | 125,9647 | -1.502 | -189 | 2.800 | ||||
| 2026-04-17 | 2026-04-15 | 4 | Goin Kathleen | PVLA | Common Stock | D | 9,0800 | 2.148 | 20 | 4.302 | ||||
| 2026-04-17 | 2026-04-15 | 4 | Goin Kathleen | PVLA | Common Stock | D | 7,1400 | 2.154 | 15 | 2.154 | ||||
| 2026-04-01 | 2026-03-30 | 4 | JENKINS GEORGE M | PVLA | Common Stock | D | 112,3000 | 445 | 50 | 187.616 | ||||
| 2026-03-20 | 2026-03-18 | 4 | Goin Kathleen | PVLA | Common Stock | D | 119,0817 | -304 | -36 | 0 | ||||
| 2026-03-20 | 2026-03-18 | 4 | Goin Kathleen | PVLA | Common Stock | D | 118,3681 | -1.730 | -205 | 304 | ||||
| 2026-03-20 | 2026-03-18 | 4 | Goin Kathleen | PVLA | Common Stock | D | 117,5632 | -2.268 | -267 | 2.034 | ||||
| 2026-03-20 | 2026-03-18 | 4 | Goin Kathleen | PVLA | Common Stock | D | 9,0800 | 2.148 | 20 | 4.302 | ||||
| 2026-03-20 | 2026-03-18 | 4 | Goin Kathleen | PVLA | Common Stock | D | 7,1400 | 2.154 | 15 | 2.154 | ||||
| 2026-03-02 | 2026-02-27 | 4 | JENKINS GEORGE M | PVLA | Common Stock | D | 125,0000 | 4.000 | 500 | 187.171 | ||||
| 2026-03-02 | 2026-02-27 | 4 | HERON ELAINE J | PVLA | Common Stock | D | 125,0000 | 2.400 | 300 | 47.812 | ||||
| 2026-02-20 | 2026-02-18 | 4 | Goin Kathleen | PVLA | Common Stock | D | 79,9651 | -1.276 | -102 | 0 | ||||
| 2026-02-20 | 2026-02-18 | 4 | Goin Kathleen | PVLA | Common Stock | D | 79,1569 | -3.026 | -240 | 1.276 | ||||
| 2026-02-20 | 2026-02-18 | 4 | Goin Kathleen | PVLA | Common Stock | D | 9,0800 | 2.148 | 20 | 4.302 | ||||
| 2026-02-20 | 2026-02-18 | 4 | Goin Kathleen | PVLA | Common Stock | D | 7,1400 | 2.154 | 15 | 2.154 | ||||
| 2026-01-23 | 2026-01-21 | 4 | Goin Kathleen | PVLA | Common Stock | D | 97,9400 | -3.749 | -367 | 0 | ||||
| 2026-01-23 | 2026-01-21 | 4 | Goin Kathleen | PVLA | Common Stock | D | 95,4900 | -553 | -53 | 3.749 | ||||
| 2026-01-23 | 2026-01-21 | 4 | Goin Kathleen | PVLA | Common Stock | D | 9,0800 | 2.148 | 20 | 4.302 | ||||
| 2026-01-23 | 2026-01-21 | 4 | Goin Kathleen | PVLA | Common Stock | D | 7,1400 | 2.154 | 15 | 2.154 | ||||
| 2025-12-19 | 2025-12-17 | 4 | Goin Kathleen | PVLA | Common Stock | D | 96,4720 | -4.302 | -415 | 0 | ||||
| 2025-12-19 | 2025-12-17 | 4 | Goin Kathleen | PVLA | Common Stock | D | 9,0800 | 2.148 | 20 | 4.302 | ||||
| 2025-12-19 | 2025-12-17 | 4 | Goin Kathleen | PVLA | Common Stock | D | 7,1400 | 2.154 | 15 | 2.154 | ||||
| 2025-11-21 | 2025-11-19 | 4 | Goin Kathleen | PVLA | Common Stock | D | 86,5053 | -2.802 | -242 | 0 | ||||
| 2025-11-21 | 2025-11-19 | 4 | Goin Kathleen | PVLA | Common Stock | D | 85,7183 | -1.500 | -129 | 2.802 | ||||
| 2025-11-21 | 2025-11-19 | 4 | Goin Kathleen | PVLA | Common Stock | D | 9,0800 | 2.148 | 20 | 4.302 | ||||
| 2025-11-21 | 2025-11-19 | 4 | Goin Kathleen | PVLA | Common Stock | D | 7,1400 | 2.154 | 15 | 2.154 | ||||
| 2025-04-10 | 2025-04-09 | 4 | JENKINS GEORGE M by foundation | PVLA | Common Stock | I | 20,2700 | 2.490 | 50 | 13.516 | ||||
| 2025-04-10 | 2025-04-09 | 4 | JENKINS GEORGE M | PVLA | Common Stock | D | 20,1300 | 2.500 | 50 | 183.171 | ||||
| 2025-01-06 | 3/A | Kaupinen Wes | PVLA | Common Stock | D | 44.410 | ||||||||
| 2024-12-19 | 2024-12-18 | 4 | JENKINS GEORGE M | PVLA | Common Stock | D | 12,9300 | 4.000 | 52 | 180.671 | ||||
| 2024-12-17 | 2024-12-13 | 4 | BVF PARTNERS L P/IL | PVLA | Common Stock, $0.001 par value | D | 29.648 | 38.961 | ||||||
| 2024-12-17 | 2024-12-13 | 4 | BVF PARTNERS L P/IL | PVLA | Common Stock, $0.001 par value | D | 174.958 | 282.223 | ||||||
| 2024-12-17 | 2024-12-13 | 4 | BVF PARTNERS L P/IL | PVLA | Common Stock, $0.001 par value | D | 234.323 | 371.916 | ||||||
| 2024-12-16 | 3 | Kaupinen Wes | PVLA | Common Stock | D | 42.940 | ||||||||
| 2024-12-16 | 3 | Kaupinen Wes by Christine L. Kaupinen 2019 Irrevocable Trust dated February 28, 2019 | PVLA | Common Stock | I | 781.409 | ||||||||
| 2024-12-16 | 3 | Kaupinen Wes by Wesley H. Kaupinen 2019 Irrevocable Trust dated February 28, 2019 | PVLA | Common Stock | I | 781.409 | ||||||||
| 2024-12-16 | 3 | Davis Todd C | PVLA | Common Stock | D | 112.547 | ||||||||
| 2024-12-16 | 3 | JENKINS GEORGE M by Eagles Mere Air Museum Foundation | PVLA | Common Stock | I | 11.026 | ||||||||
| 2024-12-16 | 3 | JENKINS GEORGE M | PVLA | Common Stock | D | 176.671 | ||||||||
| 2024-12-16 | 3 | HERON ELAINE J | PVLA | Common Stock | D | 45.412 | ||||||||
| 2024-12-16 | 3 | HERON ELAINE J by Trust | PVLA | Common Stock | I | 5.879 | ||||||||
| 2024-12-12 | 2024-12-12 | 4 | GERAGHTY JAMES A | PIRS | Series F Preferred Stock, par value $0.001 per share | D | 0,0100 | -1 | -0 | 0 | ||||
| 2024-11-18 | 3 | Dellora Investments LP | PIRS | Common Stock | I | 141.079 | ||||||||
| 2024-10-28 | 2024-08-07 | 4 | GERAGHTY JAMES A | PIRS | Series F Preferred Stock, par value $0.001 per share | D | 1,0000 | 1 | 0 | 1 | ||||
| 2024-08-12 | 2024-08-12 | 4 | ADAR1 Capital Management, LLC By: Spearhead Insurance Solutions IDF, LLC - Series ADAR1 | PIRS | Common Stock | I | 15,8824 | 757 | 12 | 15.067 | ||||
| 2024-08-12 | 2024-08-12 | 4 | ADAR1 Capital Management, LLC By: ADAR1 Partners | PIRS | Common Stock | I | 15,8824 | 2.243 | 36 | 129.574 | ||||
| 2024-08-12 | 2024-08-09 | 4 | ADAR1 Capital Management, LLC By: ADAR1 Partners | PIRS | Common Stock | I | 14,8929 | 3.000 | 45 | 127.331 | ||||
| 2024-07-31 | 3 | ADAR1 Capital Management, LLC By: Spearhead Insurance Solutions IDF, LLC - Series ADAR1 | PIRS | Common Stock | I | 14.310 | ||||||||
| 2024-07-31 | 3 | ADAR1 Capital Management, LLC By: ADAR1 Partners | PIRS | Common Stock | I | 124.331 | ||||||||
| 2023-05-30 | 2023-05-25 | 4 | KIRITSY CHRISTOPHER P | PIRS | Common Stock | D | 0,8500 | 10.000 | 8 | 20.000 | ||||
| 2023-05-22 | 3 | LAMPERT MARK N | PIRS | Common Stock, $0.001 par value | D | 8.581.171 | ||||||||
| 2023-05-22 | 3 | LAMPERT MARK N | PIRS | Common Stock, $0.001 par value | D | 744.966 | ||||||||
| 2023-05-22 | 3 | LAMPERT MARK N | PIRS | Common Stock, $0.001 par value | D | 11.007.420 | ||||||||
| 2022-05-16 | 2022-05-13 | 4 | Demuth Tim | PIRS | Common Stock | D | 1,7100 | 6.000 | 10 | 6.000 | ||||
| 2022-02-24 | 2022-02-22 | 4 | Yoder Stephen S. | PIRS | Stock Option (Right to buy) | D | 3,03 | 625.874 | 625.874 | |||||
| 2022-02-24 | 2022-02-22 | 4 | Mousa Ahmed | PIRS | Stock Option (Right to buy) | D | 3,03 | 215.819 | 215.819 | |||||
| 2022-02-24 | 2022-02-22 | 4 | Olwill Shane | PIRS | Stock Option (Right to buy) | D | 3,03 | 215.819 | 215.819 | |||||
| 2022-02-24 | 2022-02-22 | 4 | Demuth Tim | PIRS | Stock Option (Right to buy) | D | 3,03 | 100.000 | 100.000 | |||||
| 2022-02-24 | 2022-02-22 | 4 | Kaufmann Hitto | PIRS | Stock Option (Right to buy) | D | 3,03 | 215.819 | 215.819 | |||||
| 2022-02-24 | 2022-02-22 | 4 | Bures Thomas | PIRS | Stock Options (Right to buy) | D | 3,03 | 215.819 | 215.819 | |||||
| 2021-09-01 | 2021-08-30 | 4 | Olwill Shane | PIRS | Stock Option (right to buy) | D | 1,52 | -38.400 | 61.600 | |||||
| 2021-09-01 | 2021-08-30 | 4 | Olwill Shane | PIRS | Common Stock | D | 5,1500 | -29.200 | -150 | 4.638 | ||||
| 2021-09-01 | 2021-08-30 | 4 | Olwill Shane | PIRS | Common Stock | D | 5,0000 | -9.200 | -46 | 33.838 | ||||
| 2021-09-01 | 2021-08-30 | 4 | Olwill Shane | PIRS | Common Stock | D | 1,5200 | 38.400 | 58 | 43.038 | ||||
| 2021-08-03 | 2021-08-01 | 4 | Demuth Tim | PIRS | Stock Option (right to buy) | D | 3,48 | 360.000 | 360.000 | |||||
| 2021-08-03 | 3 | Olwill Shane | PIRS | Common Stock | D | 4.638 | ||||||||
| 2021-06-29 | 2021-06-25 | 4 | Sherman Matthew L | PIRS | Stock Option (right to buy) | D | 4,00 | 40.000 | 40.000 | |||||
| 2021-06-29 | 2021-06-25 | 4 | Said Maya R. | PIRS | Stock Option (right to buy) | D | 4,00 | 40.000 | 40.000 | |||||
| 2021-06-29 | 2021-06-25 | 4 | Richman Michael | PIRS | Stock Option (right to buy) | D | 4,00 | 40.000 | 40.000 | |||||
| 2021-06-29 | 2021-06-25 | 4 | KIRITSY CHRISTOPHER P | PIRS | Stock Option (right to buy) | D | 4,00 | 40.000 | 40.000 | |||||
| 2021-06-29 | 2021-06-25 | 4 | Kiener Peter A | PIRS | Stock Option (right to buy) | D | 4,00 | 40.000 | 40.000 | |||||
| 2021-06-29 | 2021-06-25 | 4 | GERAGHTY JAMES A | PIRS | Stock Option (right to buy) | D | 4,00 | 45.000 | 45.000 | |||||
| 2021-06-29 | 2021-06-25 | 4 | Barbier Ann | PIRS | Stock Option (right to buy) | D | 4,00 | 40.000 | 40.000 | |||||
| 2021-03-08 | 2021-03-04 | 4 | Bures Thomas | PIRS | Stock Options (Right to buy) | D | 2,50 | 150.000 | 150.000 | |||||
| 2021-03-08 | 2021-03-04 | 4 | Yoder Stephen S. | PIRS | Stock Options (Right to buy) | D | 2,50 | 530.000 | 530.000 | |||||
| 2021-03-08 | 2021-03-04 | 4 | Kaufmann Hitto | PIRS | Stock Options (Right to buy) | D | 2,50 | 220.000 | 220.000 | |||||
| 2020-07-22 | 2020-07-21 | 4 | Aquilo Capital Management, LLC See footnotes | PIRS | Common Stock, $0.001 par value | I | 2,9500 | -1.900.000 | -5.605 | 3.675.530 | ||||
| 2020-06-25 | 2020-06-23 | 4/A | Said Maya R. | PIRS | Stock Option (right to buy) | D | 3,27 | 40.000 | 40.000 | |||||
| 2020-06-25 | 2020-06-23 | 4/A | KIRITSY CHRISTOPHER P | PIRS | Stock Option (right to buy) | D | 3,27 | 40.000 | 40.000 | |||||
| 2020-06-25 | 2020-06-23 | 4 | Kiener Peter A | PIRS | Stock Options (Right to buy) | D | 3,27 | 40.000 | 40.000 | |||||
| 2020-06-25 | 2020-06-23 | 4 | KIRITSY CHRISTOPHER P | PIRS | Stock Option (right to buy) | D | 3,27 | 40.000 | 40.000 | |||||
| 2020-06-25 | 2020-06-23 | 4 | Richman Michael | PIRS | Stock Option (right to buy) | D | 3,27 | 40.000 | 40.000 | |||||
| 2020-06-25 | 2020-06-23 | 4 | Sherman Matthew L | PIRS | Stock Option (right to buy) | D | 3,27 | 40.000 | 40.000 | |||||
| 2020-06-25 | 2020-06-25 | 4 | Said Maya R. | PIRS | Stock Option (right to buy) | D | 3,27 | 40.000 | 40.000 | |||||
| 2020-06-25 | 2020-06-23 | 4 | Barbier Ann | PIRS | Stock Options (Right to buy) | D | 3,27 | 40.000 | 40.000 | |||||
| 2020-06-25 | 2020-06-23 | 4 | GERAGHTY JAMES A | PIRS | Stock Option (right to buy) | D | 3,27 | 45.000 | 45.000 | |||||
| 2020-03-23 | 3 | Aquilo Capital Management, LLC See footnotes | PIRS | Common Stock, $0.001 par value | I | 11.151.060 | ||||||||
| 2020-03-23 | 3 | Aquilo Capital Management, LLC See footnotes | PIRS | Common Stock, $0.001 par value | I | 11.151.060 | ||||||||
| 2020-03-23 | 3 | Aquilo Capital Management, LLC See footnotes | PIRS | Common Stock, $0.001 par value | I | 11.151.060 | ||||||||
| 2020-03-02 | 2020-02-27 | 4 | Yoder Stephen S. | PIRS | Stock Option (Right to Buy) | D | 3,15 | 420.000 | 420.000 | |||||
| 2020-03-02 | 2020-02-27 | 4 | Kaufmann Hitto | PIRS | Stock Option (Right to Buy) | D | 3,15 | 45.000 | 45.000 | |||||
| 2020-03-02 | 2020-02-27 | 4 | Bures Thomas | PIRS | Stock Option (Right to Buy) | D | 3,15 | 80.000 | 80.000 | |||||
| 2020-01-28 | 2020-01-25 | 4 | GERAGHTY JAMES A | PIRS | Stock Option (right to buy) | D | 3,23 | 22.500 | 22.500 | |||||
| 2020-01-28 | 2020-01-25 | 4 | Richman Michael | PIRS | Stock Option (right to buy) | D | 3,23 | 20.000 | 20.000 | |||||
| 2020-01-28 | 2020-01-25 | 4 | Richman Michael | PIRS | Stock Option (right to buy) | D | 3,23 | 2,1070 | 5.431 | 11 | 5.431 | |||
| 2020-01-28 | 2020-01-25 | 4 | BIZZARI JEAN-PIERRE | PIRS | Stock Option (right to buy) | D | 3,23 | 20.000 | 20.000 | |||||
| 2020-01-28 | 2020-01-25 | 4 | KIRITSY CHRISTOPHER P | PIRS | Stock Option (right to buy) | D | 3,23 | 20.000 | 20.000 | |||||
| 2020-01-28 | 2020-01-25 | 4 | Barbier Ann | PIRS | Stock Option (right to buy) | D | 3,23 | 20.000 | 20.000 | |||||
| 2020-01-28 | 2020-01-25 | 4 | Kiener Peter A | PIRS | Stock Option (right to buy) | D | 3,23 | 20.000 | 20.000 | |||||
| 2020-01-28 | 2020-01-25 | 4 | Said Maya R. | PIRS | Stock Option (right to buy) | D | 3,23 | 20.000 | 20.000 | |||||
| 2020-01-28 | 2020-01-25 | 4 | Sherman Matthew L | PIRS | Stock Option (right to buy) | D | 3,23 | 20.000 | 20.000 | |||||
| 2019-10-28 | 2019-10-25 | 4 | Richman Michael | PIRS | Stock Options (right to buy) | D | 3,24 | 2,1180 | 5.165 | 11 | 5.165 | |||
| 2019-09-10 | 3 | LAMPERT MARK N | PIRS | Common Stock, $0.001 par value | D | 7.241.062 | ||||||||
| 2019-09-10 | 3 | LAMPERT MARK N | PIRS | Common Stock, $0.001 par value | D | 5.297.535 | ||||||||
| 2019-09-10 | 3 | LAMPERT MARK N | PIRS | Common Stock, $0.001 par value | D | 5.297.535 | ||||||||
| 2019-09-10 | 3 | LAMPERT MARK N | PIRS | Common Stock, $0.001 par value | D | 7.241.062 | ||||||||
| 2019-09-10 | 3 | LAMPERT MARK N | PIRS | Common Stock, $0.001 par value | D | 7.390.475 | ||||||||
| 2019-09-10 | 3 | LAMPERT MARK N | PIRS | Common Stock, $0.001 par value | D | 5.297.535 | ||||||||
| 2019-09-10 | 3 | LAMPERT MARK N | PIRS | Common Stock, $0.001 par value | D | 5.297.535 | ||||||||
| 2019-09-10 | 3 | LAMPERT MARK N | PIRS | Common Stock, $0.001 par value | D | 7.241.062 | ||||||||
| 2019-09-10 | 3 | LAMPERT MARK N | PIRS | Common Stock, $0.001 par value | D | 7.390.475 | ||||||||
| 2019-09-10 | 3 | LAMPERT MARK N | PIRS | Common Stock, $0.001 par value | D | 5.297.535 | ||||||||
| 2019-09-10 | 3 | LAMPERT MARK N | PIRS | Common Stock, $0.001 par value | D | 7.241.062 | ||||||||
| 2019-09-10 | 3 | LAMPERT MARK N | PIRS | Common Stock, $0.001 par value | D | 7.390.475 | ||||||||
| 2019-09-10 | 3 | LAMPERT MARK N | PIRS | Common Stock, $0.001 par value | D | 5.297.535 | ||||||||
| 2019-09-10 | 3 | LAMPERT MARK N | PIRS | Common Stock, $0.001 par value | D | 7.241.062 | ||||||||
| 2019-09-10 | 3 | LAMPERT MARK N | PIRS | Common Stock, $0.001 par value | D | 7.390.475 | ||||||||
| 2019-09-10 | 3 | LAMPERT MARK N | PIRS | Common Stock, $0.001 par value | D | 7.390.475 | ||||||||
| 2019-09-10 | 3 | LAMPERT MARK N | PIRS | Common Stock, $0.001 par value | D | 7.241.062 | ||||||||
| 2019-09-10 | 3 | LAMPERT MARK N | PIRS | Common Stock, $0.001 par value | D | 5.297.535 | ||||||||
| 2019-09-10 | 3 | LAMPERT MARK N | PIRS | Common Stock, $0.001 par value | D | 7.390.475 | ||||||||
| 2019-09-10 | 3 | LAMPERT MARK N | PIRS | Common Stock, $0.001 par value | D | 7.241.062 | ||||||||
| 2019-09-10 | 3 | LAMPERT MARK N | PIRS | Common Stock, $0.001 par value | D | 5.297.535 | ||||||||
| 2019-09-10 | 3 | LAMPERT MARK N | PIRS | Common Stock, $0.001 par value | D | 7.390.475 | ||||||||
| 2019-09-10 | 3 | LAMPERT MARK N | PIRS | Common Stock, $0.001 par value | D | 7.241.062 | ||||||||
| 2019-09-10 | 3 | LAMPERT MARK N | PIRS | Common Stock, $0.001 par value | D | 7.390.475 | ||||||||
| 2019-09-10 | 3 | LAMPERT MARK N | PIRS | Common Stock, $0.001 par value | D | 7.241.062 | ||||||||
| 2019-09-10 | 3 | LAMPERT MARK N | PIRS | Common Stock, $0.001 par value | D | 5.297.535 | ||||||||
| 2019-09-10 | 3 | LAMPERT MARK N | PIRS | Common Stock, $0.001 par value | D | 7.390.475 | ||||||||
| 2019-09-10 | 2019-09-06 | 4 | BVF PARTNERS L P/IL | PIRS | Common Stock, $0.001 par value | D | 4,4994 | -1.128 | -5 | 314.139 | ||||
| 2019-09-10 | 2019-09-06 | 4 | BVF PARTNERS L P/IL | PIRS | Common Stock, $0.001 par value | D | 4,4994 | -25.720 | -116 | 2.233.074 | ||||
| 2019-09-10 | 2019-09-06 | 4 | BVF PARTNERS L P/IL | PIRS | Common Stock, $0.001 par value | D | 4,4994 | -23.152 | -104 | 2.385.055 | ||||
| 2019-09-03 | 3 | Bures Thomas | PIRS | Common Stock | D | 10.218 | ||||||||
| 2019-09-03 | 3 | Bures Thomas | PIRS | Common Stock | D | 10.218 | ||||||||
| 2019-09-03 | 3 | Bures Thomas | PIRS | Common Stock | D | 10.218 | ||||||||
| 2019-09-03 | 2019-08-30 | 4 | Kaufmann Hitto | PIRS | Stock Option (right to buy) | D | 4,65 | 300.000 | 300.000 | |||||
| 2019-08-01 | 2019-07-31 | 4 | Said Maya R. | PIRS | Stock Option (right to buy) | D | 5,50 | 30.000 | 30.000 | |||||
| 2019-07-26 | 2019-07-25 | 4 | Richman Michael | PIRS | Stock Option (right to buy) | D | 4,40 | 2,8900 | 3.789 | 11 | 3.789 | |||
| 2019-04-30 | 2019-04-25 | 4 | Richman Michael | PIRS | Stock Option (right to buy) | D | 2,94 | 1,9400 | 5.640 | 11 | 5.640 | |||
| 2019-02-28 | 2019-02-26 | 4 | Yoder Stephen S. | PIRS | Stock Options (Right to Buy) | D | 3,09 | 380.000 | 380.000 | |||||
| 2019-02-28 | 2019-02-26 | 4 | Reine Allan | PIRS | Stock Options (Right to Buy) | D | 3,09 | 162.500 | 162.500 | |||||
| 2019-02-28 | 2019-02-26 | 4 | Matis Louis | PIRS | Stock Option (Right to Buy) | D | 3,09 | 96.500 | 96.500 | |||||
| 2019-02-01 | 2019-01-30 | 4 | BVF PARTNERS L P/IL | PIRS | Series B Convertible Preferred Stock, $0.001 par value | D | 284 | 284 | ||||||
| 2019-02-01 | 2019-01-30 | 4 | BVF PARTNERS L P/IL | PIRS | Series B Convertible Preferred Stock, $0.001 par value | D | 2.143 | 2.143 | ||||||
| 2019-02-01 | 2019-01-30 | 4 | BVF PARTNERS L P/IL | PIRS | Series B Convertible Preferred Stock, $0.001 par value | D | 2.573 | 2.573 | ||||||
| 2019-02-01 | 2019-01-30 | 4 | BVF PARTNERS L P/IL | PIRS | Common Stock, $0.001 par value | D | -284.000 | 141.346 | ||||||
| 2019-02-01 | 2019-01-30 | 4 | BVF PARTNERS L P/IL | PIRS | Common Stock, $0.001 par value | D | -2.143.000 | 772.324 | ||||||
| 2019-02-01 | 2019-01-30 | 4 | BVF PARTNERS L P/IL | PIRS | Common Stock, $0.001 par value | D | -2.573.000 | 978.200 | ||||||
| 2019-01-29 | 2019-01-25 | 4 | GERAGHTY JAMES A | PIRS | Stock Option (right to buy) | D | 2,74 | 25.000 | 25.000 | |||||
| 2019-01-29 | 2019-01-25 | 4 | Barbier Ann | PIRS | Stock Option (right to buy) | D | 2,74 | 20.000 | 20.000 | |||||
| 2019-01-29 | 2019-01-25 | 4 | BIZZARI JEAN-PIERRE | PIRS | Stock Option (right to buy) | D | 2,74 | 20.000 | 20.000 | |||||
| 2019-01-29 | 2019-01-25 | 4 | Kiener Peter A | PIRS | Stock Option (right to buy) | D | 2,74 | 20.000 | 20.000 | |||||
| 2019-01-29 | 2019-01-25 | 4 | KIRITSY CHRISTOPHER P | PIRS | Stock Option (right to buy) | D | 2,74 | 20.000 | 20.000 | |||||
| 2019-01-29 | 2019-01-25 | 4 | Prelack Steven | PIRS | Stock Option (right to buy) | D | 2,74 | 20.000 | 20.000 | |||||
| 2019-01-29 | 2019-01-25 | 4 | Richman Michael | PIRS | Stock Option (right to buy) | D | 2,74 | 20.000 | 20.000 | |||||
| 2019-01-29 | 2019-01-25 | 4 | Richman Michael | PIRS | Stock Option (right to buy) | D | 2,74 | 1,7900 | 6.096 | 11 | 6.096 | |||
| 2019-01-29 | 2019-01-25 | 4 | Sherman Matthew L | PIRS | Stock Option (right to buy) | D | 2,74 | 20.000 | 20.000 | |||||
| 2018-11-26 | 3 | LAMPERT MARK N | PIRS | Common Stock, $0.001 par value | D | 10.443.070 | ||||||||
| 2018-11-26 | 3 | LAMPERT MARK N | PIRS | Common Stock, $0.001 par value | D | 9.807.194 | ||||||||
| 2018-11-26 | 3 | LAMPERT MARK N | PIRS | Common Stock, $0.001 par value | D | 7.317.216 | ||||||||
| 2018-11-26 | 3 | LAMPERT MARK N | PIRS | Common Stock, $0.001 par value | D | 9.807.194 | ||||||||
| 2018-11-26 | 3 | LAMPERT MARK N | PIRS | Common Stock, $0.001 par value | D | 7.317.216 | ||||||||
| 2018-11-26 | 3 | LAMPERT MARK N | PIRS | Common Stock, $0.001 par value | D | 10.443.070 | ||||||||
| 2018-11-26 | 3 | LAMPERT MARK N | PIRS | Common Stock, $0.001 par value | D | 10.443.070 | ||||||||
| 2018-11-26 | 3 | LAMPERT MARK N | PIRS | Common Stock, $0.001 par value | D | 9.807.194 | ||||||||
| 2018-11-26 | 3 | LAMPERT MARK N | PIRS | Common Stock, $0.001 par value | D | 7.317.216 | ||||||||
| 2018-11-26 | 3 | LAMPERT MARK N | PIRS | Common Stock, $0.001 par value | D | 10.443.070 | ||||||||
| 2018-11-26 | 3 | LAMPERT MARK N | PIRS | Common Stock, $0.001 par value | D | 9.807.194 | ||||||||
| 2018-11-26 | 3 | LAMPERT MARK N | PIRS | Common Stock, $0.001 par value | D | 7.317.216 | ||||||||
| 2018-11-26 | 3 | LAMPERT MARK N | PIRS | Common Stock, $0.001 par value | D | 10.443.070 | ||||||||
| 2018-11-26 | 3 | LAMPERT MARK N | PIRS | Common Stock, $0.001 par value | D | 9.807.194 | ||||||||
| 2018-11-26 | 3 | LAMPERT MARK N | PIRS | Common Stock, $0.001 par value | D | 7.317.216 | ||||||||
| 2018-11-26 | 3 | LAMPERT MARK N | PIRS | Common Stock, $0.001 par value | D | 10.443.070 | ||||||||
| 2018-11-26 | 3 | LAMPERT MARK N | PIRS | Common Stock, $0.001 par value | D | 9.807.194 | ||||||||
| 2018-11-26 | 3 | LAMPERT MARK N | PIRS | Common Stock, $0.001 par value | D | 7.317.216 | ||||||||
| 2018-11-26 | 3 | LAMPERT MARK N | PIRS | Common Stock, $0.001 par value | D | 10.443.070 | ||||||||
| 2018-11-26 | 3 | LAMPERT MARK N | PIRS | Common Stock, $0.001 par value | D | 9.807.194 | ||||||||
| 2018-11-26 | 3 | LAMPERT MARK N | PIRS | Common Stock, $0.001 par value | D | 7.317.216 | ||||||||
| 2018-11-26 | 3 | LAMPERT MARK N | PIRS | Common Stock, $0.001 par value | D | 10.443.070 | ||||||||
| 2018-11-26 | 3 | LAMPERT MARK N | PIRS | Common Stock, $0.001 par value | D | 9.807.194 | ||||||||
| 2018-11-26 | 3 | LAMPERT MARK N | PIRS | Common Stock, $0.001 par value | D | 7.317.216 | ||||||||
| 2018-11-26 | 3 | LAMPERT MARK N | PIRS | Common Stock, $0.001 par value | D | 10.443.070 | ||||||||
| 2018-11-26 | 3 | LAMPERT MARK N | PIRS | Common Stock, $0.001 par value | D | 9.807.194 | ||||||||
| 2018-11-26 | 3 | LAMPERT MARK N | PIRS | Common Stock, $0.001 par value | D | 7.317.216 | ||||||||
| 2018-10-29 | 2018-10-25 | 4 | Richman Michael | PIRS | Stock Option (right to buy) | D | 4,36 | 2,8600 | 3.829 | 11 | 3.829 | |||
| 2018-10-25 | 2018-10-24 | 4 | Kiener Peter A | PIRS | Stock Option (right to buy) | D | 4,46 | 30.000 | 30.000 | |||||
| 2018-10-25 | 2018-10-24 | 4 | Sherman Matthew L | PIRS | Stock Option (right to buy) | D | 4,46 | 30.000 | 30.000 | |||||
| 2018-09-17 | 2018-09-14 | 4 | KIRITSY CHRISTOPHER P | PIRS | Common Stock | D | 5,1050 | 5.000 | 26 | 10.000 | ||||
| 2018-07-26 | 2018-07-25 | 4 | Richman Michael | PIRS | Stock Option (right to buy) | D | 5,92 | 3,8600 | 2.837 | 11 | 2.837 | |||
| 2018-05-16 | 2018-05-15 | 4 | GERAGHTY JAMES A | PIRS | Common Stock | D | 5,7500 | 10.000 | 58 | 20.000 | ||||
| 2018-05-02 | 2018-04-30 | 4 | ORBIMED ADVISORS LLC See Footnotes | PIRS | Common Stock | I | 6,3500 | -10.400 | -66 | 38.870 | ||||
| 2018-05-02 | 2018-04-30 | 4 | ORBIMED ADVISORS LLC See Footnotes | PIRS | Common Stock | I | 6,3500 | -989.600 | -6.284 | 4.511.130 | ||||
| 2018-04-26 | 2018-04-25 | 4 | Barbier Ann | PIRS | Stock Option (right to buy) | D | 6,43 | 30.000 | 30.000 | |||||
| 2018-04-26 | 2018-04-25 | 4 | Richman Michael | PIRS | Stock Option (right to buy) | D | 6,43 | 4,1000 | 2.665 | 11 | 2.665 | |||
| 2018-02-26 | 2018-02-20 | 4 | Yoder Stephen S. | PIRS | Stock Options (Right to buy) | D | 8,56 | 325.000 | 325.000 | |||||
| 2018-02-26 | 2018-02-20 | 4 | Reine Allan | PIRS | Stock Options (Right to buy) | D | 5,00 | 50.000 | 50.000 | |||||
| 2018-02-26 | 2018-02-20 | 4 | Reine Allan | PIRS | Stock Options (Right to buy) | D | 8,56 | 53.833 | 53.833 | |||||
| 2018-02-26 | 2018-02-20 | 4 | Matis Louis | PIRS | Stock Options (Right to buy) | D | 8,56 | 100.000 | 100.000 | |||||
| 2018-02-15 | 2018-02-13 | 4 | ORBIMED ADVISORS LLC See Footnotes | PIRS | Stock Option (right to buy) | I | 5,08 | -17 | 0 | |||||
| 2018-02-15 | 2018-02-13 | 4 | ORBIMED ADVISORS LLC See Footnotes | PIRS | Stock Option (right to buy) | I | 5,08 | -1.765 | 0 | |||||
| 2018-02-15 | 2018-02-13 | 4 | ORBIMED ADVISORS LLC See Footnotes | PIRS | Stock Option (right to buy) | I | 4,68 | -58 | 0 | |||||
| 2018-02-15 | 2018-02-13 | 4 | ORBIMED ADVISORS LLC See Footnotes | PIRS | Stock Option (right to buy) | I | 4,68 | -6.057 | 0 | |||||
| 2018-02-15 | 2018-02-13 | 4 | ORBIMED ADVISORS LLC See Footnotes | PIRS | Common Stock | I | 8,9800 | -75 | -1 | 49.270 | ||||
| 2018-02-15 | 2018-02-13 | 4 | ORBIMED ADVISORS LLC See Footnotes | PIRS | Common Stock | I | 8,9800 | -7.822 | -70 | 5.500.730 | ||||
| 2018-02-15 | 2018-02-13 | 4 | ORBIMED ADVISORS LLC See Footnotes | PIRS | Common Stock | I | 5,0800 | 17 | 0 | 49.345 | ||||
| 2018-02-15 | 2018-02-13 | 4 | ORBIMED ADVISORS LLC See Footnotes | PIRS | Common Stock | I | 5,0800 | 1.765 | 9 | 5.508.552 | ||||
| 2018-02-15 | 2018-02-13 | 4 | ORBIMED ADVISORS LLC See Footnotes | PIRS | Common Stock | I | 4,6800 | 58 | 0 | 49.328 | ||||
| 2018-02-15 | 2018-02-13 | 4 | ORBIMED ADVISORS LLC See Footnotes | PIRS | Common Stock | I | 4,6800 | 6.057 | 28 | 5.506.787 | ||||
| 2018-01-29 | 2018-01-25 | 4 | GERAGHTY JAMES A | PIRS | Stock Option (right to buy) | D | 7,72 | 25.000 | 25.000 | |||||
| 2018-01-29 | 2018-01-25 | 4 | Prelack Steven | PIRS | Stock Option (right to buy) | D | 7,72 | 20.000 | 20.000 | |||||
| 2018-01-29 | 2018-01-25 | 4 | Richman Michael | PIRS | Stock Option (right to buy) | D | 7,72 | 20.000 | 20.000 | |||||
| 2018-01-29 | 2018-01-25 | 4 | Richman Michael | PIRS | Stock Option (right to buy) | D | 7,72 | 5,0900 | 2.243 | 11 | 2.243 | |||
| 2018-01-29 | 2018-01-25 | 4 | BIZZARI JEAN-PIERRE | PIRS | Stock Option (right to buy) | D | 7,72 | 20.000 | 20.000 | |||||
| 2018-01-29 | 2018-01-25 | 4 | ADAMS JULIAN | PIRS | Stock Option (right to buy) | D | 7,72 | 20.000 | 20.000 | |||||
| 2018-01-29 | 2018-01-25 | 4 | KIRITSY CHRISTOPHER P | PIRS | Stock Option (right to buy) | D | 7,72 | 20.000 | 20.000 | |||||
| 2018-01-04 | 2018-01-03 | 4 | ORBIMED ADVISORS LLC See Footnotes | PIRS | Common Stock | I | 7,3500 | -16.128 | -119 | 49.270 | ||||
| 2018-01-04 | 2018-01-03 | 4 | ORBIMED ADVISORS LLC See Footnotes | PIRS | Common Stock | I | 7,3500 | -1.693.492 | -12.447 | 5.500.730 | ||||
| 2017-12-20 | 2017-12-18 | 4 | ORBIMED ADVISORS LLC See Footnotes | PIRS | Stock Option (right to buy) | I | 5,64 | -47 | 0 | |||||
| 2017-12-20 | 2017-12-18 | 4 | ORBIMED ADVISORS LLC See Footnotes | PIRS | Stock Option (right to buy) | I | 5,64 | -4.971 | 0 | |||||
| 2017-12-20 | 2017-12-18 | 4 | ORBIMED ADVISORS LLC See Footnotes | PIRS | Stock Option (right to buy) | I | 2,32 | -99 | 0 | |||||
| 2017-12-20 | 2017-12-18 | 4 | ORBIMED ADVISORS LLC See Footnotes | PIRS | Stock Option (right to buy) | I | 2,32 | -10.447 | 0 | |||||
| 2017-12-20 | 2017-12-18 | 4 | ORBIMED ADVISORS LLC See Footnotes | PIRS | Stock Option (right to buy) | I | 1,62 | -97 | 0 | |||||
| 2017-12-20 | 2017-12-18 | 4 | ORBIMED ADVISORS LLC See Footnotes | PIRS | Stock Option (right to buy) | I | 2,01 | -97 | 0 | |||||
| 2017-12-20 | 2017-12-18 | 4 | ORBIMED ADVISORS LLC See Footnotes | PIRS | Stock Option (right to buy) | I | 2,01 | -10.216 | 0 | |||||
| 2017-12-20 | 2017-12-18 | 4 | ORBIMED ADVISORS LLC See Footnotes | PIRS | Stock Option (right to buy) | I | 2,01 | -142 | 0 | |||||
| 2017-12-20 | 2017-12-18 | 4 | ORBIMED ADVISORS LLC See Footnotes | PIRS | Stock Option (right to buy) | I | 2,01 | -14.858 | 0 | |||||
| 2017-12-20 | 2017-12-18 | 4 | ORBIMED ADVISORS LLC See Footnotes | PIRS | Stock Option (right to buy) | I | 1,64 | -97 | 0 | |||||
| 2017-12-20 | 2017-12-18 | 4 | ORBIMED ADVISORS LLC See Footnotes | PIRS | Stock Option (right to buy) | I | 1,64 | -10.182 | 0 | |||||
| 2017-12-20 | 2017-12-18 | 4 | ORBIMED ADVISORS LLC See Footnotes | PIRS | Stock Option (right to buy) | I | 1,73 | -92 | 0 | |||||
| 2017-12-20 | 2017-12-18 | 4 | ORBIMED ADVISORS LLC See Footnotes | PIRS | Stock Option (right to buy) | I | 1,73 | -9.642 | 0 | |||||
| 2017-12-20 | 2017-12-18 | 4 | ORBIMED ADVISORS LLC See Footnotes | PIRS | Stock Option (right to buy) | I | 2,05 | -77 | 0 | |||||
| 2017-12-20 | 2017-12-18 | 4 | ORBIMED ADVISORS LLC See Footnotes | PIRS | Stock Option (right to buy) | I | 2,05 | -8.097 | 0 | |||||
| 2017-12-20 | 2017-12-18 | 4 | ORBIMED ADVISORS LLC See Footnotes | PIRS | Stock Option (right to buy) | I | 1,59 | -189 | 0 | |||||
| 2017-12-20 | 2017-12-18 | 4 | ORBIMED ADVISORS LLC See Footnotes | PIRS | Stock Option (right to buy) | I | 1,59 | -19.811 | 0 | |||||
| 2017-12-20 | 2017-12-18 | 4 | ORBIMED ADVISORS LLC See Footnotes | PIRS | Stock Option (right to buy) | I | 1,62 | -10.180 | 0 | |||||
| 2017-12-20 | 2017-12-18 | 4 | ORBIMED ADVISORS LLC See Footnotes | PIRS | Stock Option (right to buy) | I | 1,94 | -83 | 0 | |||||
| 2017-12-20 | 2017-12-18 | 4 | ORBIMED ADVISORS LLC See Footnotes | PIRS | Stock Option (right to buy) | I | 1,94 | -8.717 | 0 | |||||
| 2017-12-20 | 2017-12-18 | 4 | ORBIMED ADVISORS LLC See Footnotes | PIRS | Stock Option (right to buy) | I | 2,62 | -63 | 0 | |||||
| 2017-12-20 | 2017-12-18 | 4 | ORBIMED ADVISORS LLC See Footnotes | PIRS | Stock Option (right to buy) | I | 2,62 | -6.654 | 0 | |||||
| 2017-12-20 | 2017-12-18 | 4 | ORBIMED ADVISORS LLC See Footnotes | PIRS | Stock Option (right to buy) | I | 3,00 | -50 | 0 | |||||
| 2017-12-20 | 2017-12-18 | 4 | ORBIMED ADVISORS LLC See Footnotes | PIRS | Stock Option (right to buy) | I | 3,00 | -5.227 | 0 | |||||
| 2017-12-20 | 2017-12-18 | 4 | ORBIMED ADVISORS LLC See Footnotes | PIRS | Stock Option (right to buy) | I | 2,00 | -259 | 0 | |||||
| 2017-12-20 | 2017-12-18 | 4 | ORBIMED ADVISORS LLC See Footnotes | PIRS | Stock Option (right to buy) | I | 2,00 | -27.241 | 0 | |||||
| 2017-12-20 | 2017-12-18 | 4 | ORBIMED ADVISORS LLC See Footnotes | PIRS | Common Stock | I | 5,7000 | -1.392 | -8 | 65.398 | ||||
| 2017-12-20 | 2017-12-18 | 4 | ORBIMED ADVISORS LLC See Footnotes | PIRS | Common Stock | I | 5,7000 | -146.243 | -834 | 7.194.222 | ||||
| 2017-12-20 | 2017-12-18 | 4 | ORBIMED ADVISORS LLC See Footnotes | PIRS | Common Stock | I | 5,6400 | 47 | 0 | 66.790 | ||||
| 2017-12-20 | 2017-12-18 | 4 | ORBIMED ADVISORS LLC See Footnotes | PIRS | Common Stock | I | 5,6400 | 4.971 | 28 | 7.340.465 | ||||
| 2017-12-20 | 2017-12-18 | 4 | ORBIMED ADVISORS LLC See Footnotes | PIRS | Common Stock | I | 2,3200 | 99 | 0 | 66.743 | ||||
| 2017-12-20 | 2017-12-18 | 4 | ORBIMED ADVISORS LLC See Footnotes | PIRS | Common Stock | I | 2,3200 | 10.447 | 24 | 7.335.494 | ||||
| 2017-12-20 | 2017-12-18 | 4 | ORBIMED ADVISORS LLC See Footnotes | PIRS | Common Stock | I | 2,0100 | 97 | 0 | 66.644 | ||||
| 2017-12-20 | 2017-12-18 | 4 | ORBIMED ADVISORS LLC See Footnotes | PIRS | Common Stock | I | 2,0100 | 10.216 | 21 | 7.325.047 | ||||
| 2017-12-20 | 2017-12-18 | 4 | ORBIMED ADVISORS LLC See Footnotes | PIRS | Common Stock | I | 2,0100 | 142 | 0 | 66.547 | ||||
| 2017-12-20 | 2017-12-18 | 4 | ORBIMED ADVISORS LLC See Footnotes | PIRS | Common Stock | I | 2,0100 | 14.858 | 30 | 7.314.831 | ||||
| 2017-12-20 | 2017-12-18 | 4 | ORBIMED ADVISORS LLC See Footnotes | PIRS | Common Stock | I | 1,6400 | 97 | 0 | 66.405 | ||||
| 2017-12-20 | 2017-12-18 | 4 | ORBIMED ADVISORS LLC See Footnotes | PIRS | Common Stock | I | 1,6400 | 10.182 | 17 | 7.299.973 | ||||
| 2017-12-20 | 2017-12-18 | 4 | ORBIMED ADVISORS LLC See Footnotes | PIRS | Common Stock | I | 1,7300 | 92 | 0 | 66.308 | ||||
| 2017-12-20 | 2017-12-18 | 4 | ORBIMED ADVISORS LLC See Footnotes | PIRS | Common Stock | I | 1,7300 | 9.642 | 17 | 7.289.791 | ||||
| 2017-12-20 | 2017-12-18 | 4 | ORBIMED ADVISORS LLC See Footnotes | PIRS | Common Stock | I | 2,0500 | 77 | 0 | 66.216 | ||||
| 2017-12-20 | 2017-12-18 | 4 | ORBIMED ADVISORS LLC See Footnotes | PIRS | Common Stock | I | 2,0500 | 8.097 | 17 | 7.280.149 | ||||
| 2017-12-20 | 2017-12-18 | 4 | ORBIMED ADVISORS LLC See Footnotes | PIRS | Common Stock | I | 1,5900 | 189 | 0 | 66.139 | ||||
| 2017-12-20 | 2017-12-18 | 4 | ORBIMED ADVISORS LLC See Footnotes | PIRS | Common Stock | I | 1,5900 | 19.811 | 31 | 7.272.052 | ||||
| 2017-12-20 | 2017-12-18 | 4 | ORBIMED ADVISORS LLC See Footnotes | PIRS | Common Stock | I | 1,6200 | 97 | 0 | 65.950 | ||||
| 2017-12-20 | 2017-12-18 | 4 | ORBIMED ADVISORS LLC See Footnotes | PIRS | Common Stock | I | 1,6200 | 10.180 | 16 | 7.252.241 | ||||
| 2017-12-20 | 2017-12-18 | 4 | ORBIMED ADVISORS LLC See Footnotes | PIRS | Common Stock | I | 1,9400 | 83 | 0 | 65.853 | ||||
| 2017-12-20 | 2017-12-18 | 4 | ORBIMED ADVISORS LLC See Footnotes | PIRS | Common Stock | I | 1,9400 | 8.717 | 17 | 7.242.061 | ||||
| 2017-12-20 | 2017-12-18 | 4 | ORBIMED ADVISORS LLC See Footnotes | PIRS | Common Stock | I | 2,6200 | 63 | 0 | 65.770 | ||||
| 2017-12-20 | 2017-12-18 | 4 | ORBIMED ADVISORS LLC See Footnotes | PIRS | Common Stock | I | 2,6200 | 6.654 | 17 | 7.233.344 | ||||
| 2017-12-20 | 2017-12-18 | 4 | ORBIMED ADVISORS LLC See Footnotes | PIRS | Common Stock | I | 3,0000 | 50 | 0 | 65.707 | ||||
| 2017-12-20 | 2017-12-18 | 4 | ORBIMED ADVISORS LLC See Footnotes | PIRS | Common Stock | I | 3,0000 | 5.227 | 16 | 7.226.690 | ||||
| 2017-12-20 | 2017-12-18 | 4 | ORBIMED ADVISORS LLC See Footnotes | PIRS | Common Stock | I | 2,0000 | 259 | 1 | 65.657 | ||||
| 2017-12-20 | 2017-12-18 | 4 | ORBIMED ADVISORS LLC See Footnotes | PIRS | Common Stock | I | 2,0000 | 27.241 | 54 | 7.221.463 | ||||
| 2017-12-14 | 2017-12-12 | 4 | GERAGHTY JAMES A | PIRS | Stock Option (right to buy) | D | 5,79 | 40.000 | 40.000 | |||||
| 2017-10-27 | 2017-10-25 | 4 | Khuong Chau Quang | PIRS | Stock Options (Right to buy) | D | 4,68 | 6.115 | 6.115 | |||||
| 2017-10-27 | 2017-10-25 | 4 | Richman Michael | PIRS | Stock Option (Rights to buy) | D | 4,68 | 4.006 | 4.006 | |||||
| 2017-08-17 | 2017-08-17 | 4 | Reine Allan | PIRS | Common Stock | D | 4,8900 | 20.000 | 98 | 65.000 | ||||
| 2017-08-17 | 2017-08-16 | 4 | Reine Allan | PIRS | Common Stock | D | 4,7900 | 45.000 | 216 | 45.000 | ||||
| 2017-08-17 | 2017-08-17 | 4 | GERAGHTY JAMES A | PIRS | Common Stock | D | 4,8200 | 10.000 | 48 | 10.000 | ||||
| 2017-08-11 | 2017-08-09 | 4 | Reine Allan | PIRS | Common Stock | D | 5,00 | 450.000 | 450.000 | |||||
| 2017-07-27 | 2017-07-25 | 4 | Richman Michael | PIRS | Stock Option (right to buy) | D | 5,64 | 3.288 | 3.288 | |||||
| 2017-07-27 | 2017-07-25 | 4 | Khuong Chau Quang | PIRS | Stock Option (right to buy) | D | 5,64 | 5.018 | 5.018 | |||||
| 2017-05-24 | 2017-05-22 | 4 | GERAGHTY JAMES A | PIRS | Stock Option (right to buy) | D | 3,94 | 30.000 | 30.000 | |||||
| 2017-05-09 | 2017-04-21 | 4 | KIRITSY CHRISTOPHER P | PIRS | Stock Option (right to buy) | D | 1,59 | -5.000 | 25.000 | |||||
| 2017-05-09 | 2017-04-21 | 4 | KIRITSY CHRISTOPHER P | PIRS | Common Stock | D | 1,5900 | 5.000 | 8 | 5.000 | ||||
| 2017-04-27 | 2017-04-25 | 4 | Richman Michael | PIRS | Stock Option (right to buy) | D | 2,32 | 7.821 | 7.821 | |||||
| 2017-04-27 | 2017-04-25 | 4 | Khuong Chau Quang | PIRS | Stock Option (right to buy) | D | 2,32 | 10.546 | 10.546 | |||||
| 2017-03-06 | 2017-02-23 | 4 | Matis Louis | PIRS | Stock option (Right to buy) | D | 1,99 | 145.000 | 145.000 | |||||
| 2017-03-06 | 2017-02-23 | 4 | Yoder Stephen S. | PIRS | Stock Option (Right to buy) | D | 1,99 | 434.350 | 434.350 | |||||
| 2017-01-30 | 2017-01-25 | 4 | Prelack Steven | PIRS | Stock Option (right to buy) | D | 2,01 | 20.000 | 20.000 | |||||
| 2017-01-30 | 2017-01-25 | 4 | Richman Michael | PIRS | Stock Option (right to buy) | D | 2,01 | 20.000 | 20.000 | |||||
| 2017-01-30 | 2017-01-25 | 4 | Richman Michael | PIRS | Stock Option (right to buy) | D | 2,01 | 9.687 | 9.687 | |||||
| 2017-01-30 | 2017-01-25 | 4 | ADAMS JULIAN | PIRS | Stock Option (right to buy) | D | 2,01 | 20.000 | 20.000 | |||||
| 2017-01-30 | 2017-01-25 | 4 | KIRITSY CHRISTOPHER P | PIRS | Stock Option (right to buy) | D | 2,01 | 20.000 | 20.000 | |||||
| 2017-01-30 | 2017-01-25 | 4 | Khuong Chau Quang | PIRS | Stock Option (right to buy) | D | 2,01 | 20.000 | 20.000 | |||||
| 2017-01-30 | 2017-01-25 | 4 | Khuong Chau Quang | PIRS | Stock Option (right to buy) | D | 2,01 | 10.313 | 10.313 | |||||
| 2017-01-30 | 2017-01-25 | 4 | BIZZARI JEAN-PIERRE | PIRS | Stock Option (right to buy) | D | 2,01 | 20.000 | 20.000 | |||||
| 2016-11-30 | 2016-11-28 | 4 | Knopf Claude | PIRS | Common Stock | D | 1,45 | 500.000 | 500.000 | |||||
| 2016-10-27 | 2016-10-25 | 4 | Richman Michael | PIRS | Stock Option (right to buy) | D | 1,64 | 9.656 | 9.656 | |||||
| 2016-10-27 | 2016-10-25 | 4 | Khuong Chau Quang | PIRS | Stock Option (right to buy) | D | 1,64 | 10.279 | 10.279 | |||||
| 2016-09-22 | 2016-09-20 | 4 | KIRITSY CHRISTOPHER P | PIRS | Stock Option (right to buy) | D | 1,59 | 30.000 | 30.000 | |||||
| 2016-08-01 | 2016-07-25 | 4 | Richman Michael | PIRS | Stock Option (right to buy) | D | 1,73 | 9.144 | 9.144 | |||||
| 2016-08-01 | 2016-07-25 | 4 | Khuong Chau Quang | PIRS | Stock Option (right to buy) | D | 1,73 | 9.734 | 9.734 | |||||
| 2016-07-26 | 2016-07-25 | 4 | ADAMS JULIAN | PIRS | Stock Option (right to buy) | D | 1,73 | 30.000 | 30.000 | |||||
| 2016-06-15 | 2016-06-13 | 4 | DEPTULA-HICKS DARLENE M | PIRS | Common Stock | D | 1,6600 | 5.000 | 8 | 5.000 | ||||
| 2016-06-15 | 2016-06-13 | 4 | Yoder Stephen S. | PIRS | Common Stock | D | 1,6800 | 6.000 | 10 | 6.000 | ||||
| 2016-06-15 | 2016-06-14 | 4 | Matis Louis | PIRS | Common Stock | D | 1,7100 | 7.915 | 14 | 10.000 | ||||
| 2016-06-15 | 2016-06-13 | 4 | Matis Louis | PIRS | Common Stock | D | 1,6800 | 2.085 | 4 | 2.085 | ||||
| 2016-04-29 | 2016-04-27 | 4 | Richman Michael | PIRS | Stock Option (right to buy) | D | 2,05 | 7.679 | 7.679 | |||||
| 2016-04-29 | 2016-04-27 | 4 | Khuong Chau Quang | PIRS | Stock Option (right to buy) | D | 2,05 | 8.174 | 8.174 | |||||
| 2016-02-18 | 2016-02-16 | 4 | Richman Michael | PIRS | Stock Option (right to buy) | D | 1,59 | 20.000 | 20.000 | |||||
| 2016-02-18 | 2016-02-16 | 4 | Prelack Steven | PIRS | Stock Option (right to buy) | D | 1,59 | 20.000 | 20.000 | |||||
| 2016-02-18 | 2016-02-16 | 4 | Khuong Chau Quang | PIRS | Stock Option (right to buy) | D | 1,59 | 20.000 | 20.000 | |||||
| 2016-02-18 | 2016-02-16 | 4 | BIZZARI JEAN-PIERRE | PIRS | Stock Option (right to buy) | D | 1,59 | 20.000 | 20.000 | |||||
| 2016-02-17 | 2016-02-12 | 4 | Yoder Stephen S. | PIRS | Stock Option (right to buy) | D | 1,52 | 492.000 | 492.000 | |||||
| 2016-01-20 | 2016-01-15 | 4 | Khuong Chau Quang | PIRS | Stock Option (right to buy) | D | 1,62 | 10.277 | 10.277 | |||||
| 2016-01-20 | 2016-01-15 | 4 | Richman Michael | PIRS | Stock Option (right to buy) | D | 1,62 | 9.654 | 9.654 | |||||
| 2015-10-30 | 2015-10-15 | 4 | Khuong Chau Quang | PIRS | Stock Option (right to buy) | D | 1,94 | 8.800 | 8.800 | |||||
| 2015-10-30 | 2015-10-15 | 4 | Richman Michael | PIRS | Stock Option (right to buy) | D | 1,94 | 8.267 | 8.267 | |||||
| 2015-09-03 | 2015-09-01 | 4 | DEPTULA-HICKS DARLENE M | PIRS | Common Stock | D | 2,80 | 450.000 | 450.000 | |||||
| 2015-08-18 | 2015-08-17 | 4 | Matis Louis | PIRS | Common Stock | D | 3,36 | 500.000 | 500.000 | |||||
| 2015-07-17 | 2015-07-15 | 4 | Khuong Chau Quang | PIRS | Stock Option (right to buy) | D | 2,55 | 6.717 | 6.717 | |||||
| 2015-07-17 | 2015-07-15 | 4 | Richman Michael | PIRS | Stock Option (right to buy) | D | 2,55 | 6.310 | 6.310 | |||||
| 2015-07-08 | 2015-07-06 | 4 | Khuong Chau Quang See Footnotes | PIRS | Common Stock | I | 2,7500 | 4.717 | 13 | 65.398 | ||||
| 2015-07-08 | 2015-07-06 | 4 | Khuong Chau Quang See Footnotes | PIRS | Common Stock | I | 2,7500 | 495.283 | 1.362 | 7.194.222 | ||||
| 2015-07-08 | 2015-07-06 | 4 | ORBIMED ADVISORS LLC See Footnotes | PIRS | Common Stock | I | 2,7500 | 4.717 | 13 | 65.398 | ||||
| 2015-07-08 | 2015-07-06 | 4 | ORBIMED ADVISORS LLC See Footnotes | PIRS | Common Stock | I | 2,7500 | 495.283 | 1.362 | 7.194.222 | ||||
| 2015-06-29 | 3 | Khuong Chau Quang See Footnotes | PIRS | Common Stock | I | 13.458.559 | ||||||||
| 2015-06-29 | 3 | Khuong Chau Quang See Footnotes | PIRS | Common Stock | I | 6.820.301 | ||||||||
| 2015-06-29 | 3 | Khuong Chau Quang See Footnotes | PIRS | Common Stock | I | 13.458.559 | ||||||||
| 2015-06-29 | 3 | Khuong Chau Quang See Footnotes | PIRS | Common Stock | I | 6.820.301 | ||||||||
| 2015-06-29 | 3 | ISALY SAMUEL D See Footnotes | PIRS | Common Stock | I | 13.458.559 | ||||||||
| 2015-06-29 | 3 | ISALY SAMUEL D See Footnotes | PIRS | Common Stock | I | 13.458.559 | ||||||||
| 2015-06-29 | 3 | ISALY SAMUEL D See Footnotes | PIRS | Common Stock | I | 13.458.559 | ||||||||
| 2015-06-29 | 3 | ISALY SAMUEL D See Footnotes | PIRS | Common Stock | I | 6.820.301 | ||||||||
| 2015-06-29 | 3 | ISALY SAMUEL D See Footnotes | PIRS | Common Stock | I | 6.820.301 | ||||||||
| 2015-06-29 | 3 | ISALY SAMUEL D See Footnotes | PIRS | Common Stock | I | 13.458.559 | ||||||||
| 2015-06-29 | 3 | ISALY SAMUEL D See Footnotes | PIRS | Common Stock | I | 6.820.301 | ||||||||
| 2015-06-29 | 3 | ISALY SAMUEL D See Footnotes | PIRS | Common Stock | I | 6.820.301 |
P
Offener Markt oder privater Kauf von nicht-derivativen oder derivativen Wertpapieren
S
Freiverkauf oder privater Verkauf von nicht-derivativen oder derivativen Wertpapieren
A
Gewährung, Vergabe oder sonstiger Erwerb von Wertpapieren des Unternehmens (z. B. eine Option)
C
Umwandlung von Derivaten
D
Verkauf oder Rückübertragung von Wertpapieren an das Unternehmen
F
Zahlung des Ausübungspreises oder der Steuerschuld mit einem Teil der vom Unternehmen erhaltenen Wertpapiere
G
Schenkung von Wertpapieren durch oder an den Insider
K
Aktien-Swaps und ähnliche Absicherungstransaktionen
M
Ausübung oder Umwandlung eines vom Unternehmen erhaltenen derivativen Wertpapiers (z. B. einer Option)
V
Eine freiwillig auf Formular 4 gemeldete Transaktion
J
Sonstige (mit einer Fußnote zur Beschreibung der Transaktion)
