| Insider-Aktien | 21.702.696 shares |
| Insider gesamt | 60 |
Insider-Stimmungswert
Der Insider-Stimmungswert ermittelt die Unternehmen, die von Unternehmensinsidern gekauft werden.
Es ist das Ergebnis eines ausgeklügelten quantitativen Multifaktormodells, das die Unternehmen mit der höchsten Insiderakkumulation identifiziert. Das Scoring-Modell verwendet eine Kombination aus der Nettozahl der Insiderkäufe der letzten 90 Tage, der Gesamtzahl der gekauften Aktien als Prozentsatz des Streubesitzes und der Gesamtzahl der von Insidern gehaltenen Aktien. Die Zahl reicht von 0 bis 100, wobei höhere Zahlen ein höheres Maß an Insiderkäufen anzeigen als bei anderen Unternehmen und 50 den Durchschnitt darstellt.
Aktualisierungshäufigkeit: Täglich
Führungskräfte-Stimmungswert
Der Führungskräfte-Stimmungswert findet Unternehmen, die von Führungskräften des Unternehmens gekauft werden.
Per Definition sind Führungskräfte des Unternehmens Insider, aber im Gegensatz zu anderen Insidern (10%ige Aktionäre und Vorstandsmitglieder) arbeiten Führungskräfte täglich für das Unternehmen und verwenden beim Handel ihr eigenes Geld. (10%ige Aktionäre und Vorstandsmitglieder sind oft Fondsmanager, die das Geld anderer Leute verwalten.) Daher sind Insider-Geschäfte, die von Führungskräften getätigt werden, viel bedeutender und sollten entsprechend behandelt werden.
Wie der Insider-Stimmungswert ist auch der Führungskräfte-Stimmungswert das Ergebnis eines ausgeklügelten quantitativen Multifaktormodells, das die Unternehmen mit der höchsten Führungskräftekonzentration identifiziert.
Aktualisierungshäufigkeit: Täglich
Wichtige Insider-Kennzahlen
Diese Karte zeigt, wie das Unternehmen bei verschiedenen Insider-Kennzahlen abschneidet. Der Perzentil-Rang zeigt, wie dieses Unternehmen im Vergleich zu anderen Unternehmen auf den US-Märkten abschneidet. Höhere Ränge deuten auf eine bessere Situation hin.
Es ist beispielsweise allgemein anerkannt, dass Insiderkäufe ein positiver Indikator sind, so dass Unternehmen mit mehr Insiderkäufen besser abschneiden würden als Unternehmen mit weniger Insiderkäufen (oder sogar Insiderverkäufen).
Prozent des Streubesitzes von Insidern gekauft (Rang)
N/A
Prozent des von Insidern gekauften Streubesitzes ist die Gesamtzahl der von Insidern gekauften Aktien abzüglich der Gesamtzahl der von Insidern in den letzten 90 Tagen verkauften Aktien, geteilt durch den gesamten Streubesitz und multipliziert mit 100.
Diagramm zum Insiderhandel
Tidal Trust Iii - Rcn Pareto Strategic Allocation Etf Insider-Trades sind in der folgenden Grafik dargestellt. Insider sind leitende Angestellte, Direktoren oder bedeutende Investoren in einem Unternehmen. Im Allgemeinen ist es für Insider illegal, auf der Grundlage von wesentlichen, nicht-öffentlichen Informationen mit Aktien ihrer Unternehmen zu handeln. Das bedeutet nicht, dass es für sie illegal ist, irgendwelche Geschäfte in ihren eigenen Unternehmen zu tätigen. Sie müssen jedoch alle Geschäfte der SEC über ein Formular 4 melden.
Kennzahlen zu Insiderlisten und Rentabilität
Diese Tabelle zeigt die Liste der bekannten Insider und wird automatisch aus den bei der SEC eingereichten Unterlagen erstellt. Zusätzlich zu den Namen, dem letzten Titel und der Bezeichnung als Direktor, leitender Angestellter oder 10%-iger Anteilseigner geben wir die zuletzt veröffentlichten Bestände an. Zusätzlich stellen wir, wenn möglich, die historische Handelsperformance für den Insider zur Verfügung. Die historische Handelsperformance ist ein gewichteter Durchschnitt der Performance tatsächlicher offener Kauftransaktionen, die von dem Insider getätigt wurden. Weitere Informationen zur Berechnung dieses Wertes finden Sie in diesem YouTube-Webinar.
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| Insider | Durchschnittlicher Gewinn (%) | Aktien in Besitz |
Split Angepasst |
|---|---|---|---|
| LLP Abingworth - | 2.144.517 | 2.144.517 | |
| Luke M Beshar Director - [D] | 198.000 | 198.000 | |
| Garen G Bohlin Director - [D] | 53.312 | 53.312 | |
| Jathin Bandari Chief Medical Officer - [O] | 56.704 | 56.704 | |
|
Hubert Birner
Director, 10% Owner -
[D]
|
12.700 | ||
| Scott Braunstein Director - [D] | 26.500 | 26.500 | |
| Steven Keith Burke SVP and Chief Medical Officer - [O] | 26.332 | 26.332 | |
| William Conkling Chief Commercial Officer - [O] | 69.992 | 69.992 | |
| Scott A Canute | 12.700 | ||
| Julio Casoy Chief Medical Officer - [O] | 45.500 | 45.500 | |
|
Management Co Deerfield
10% Owner -
|
12.700 | 0 | |
| Deerfield Partners, L.p. Director - [D] | 0 | 0 | |
| Blaine Davis Chief Financial Officer - [O] | 20.662 | 20.662 | |
| Deerfield International Master Fund, L.P. Director - [D] | 0 | 0 | |
|
Deerfield Mgmt III, L.P.
10% Owner -
|
1.311.766 | 1.311.766 | |
| Deerfield Mgmt IV, L.P. Director - [D] | 1.311.766 | 1.311.766 | |
|
Deerfield Mgmt L.P.
10% Owner -
|
0 | 0 | |
|
Deerfield Private Design Fund III, L.P.
10% Owner -
|
1.311.766 | 1.311.766 | |
| Deerfield Private Design Fund IV, L.P. Director - [D] | 1.311.766 | 1.311.766 | |
|
Deerfield Special Situations Fund, L.P.
10% Owner -
|
1.311.766 | 1.311.766 |
| Insider | Durchschnittlicher Gewinn (%) | Aktien in Besitz |
Split Angepasst |
|---|---|---|---|
|
Deerfield Special Situations International Master Fund, L.P.
10% Owner -
|
170.371 | 170.371 | |
| George Arthur Eldridge, Sr VP, CFO, Treasr, Asst Secy - [O] | 29.132 | 29.132 | |
| Patrick Fabbio Chief Financial Officer - [O] | 64.115 | 64.115 | |
|
Stefan Fischer
10% Owner -
|
500 | 1.943.059 | |
| Barry P Flannelly | 26.250 | ||
| James E Flynn Director - [D] | 0 | 0 | |
|
John Gordon Freund
10% Owner -
|
2.175.882 | 2.175.882 | |
| Hannah Fry VP, Controller - [O] | 42.723 | 42.723 | |
| Roger Garceau Director - [D] | 33.000 | 33.000 | |
|
Alexandra Goll
10% Owner -
|
1.943.059 | 1.943.059 | |
| Daniel Philip Gottlieb VP Corporate Development - [O] | 244 | 244 | |
| Paul J Hastings Director - [D] | 13.272 | 13.272 | |
| Timothy Haines - | 2.144.517 | 2.144.517 | |
| Bradley J Hartman | 70.000 | ||
|
Yasunori Kaneko
10% Owner -
|
1.432.930 | 1.432.930 | |
| Stuart A Kingsley | 12.700 | ||
|
Dmitry Kobyzev
Director, 10% Owner -
[D]
|
1.165.344 | 1.165.344 | |
| Matthew Paul Kowalsky VP, Legal and Secretary - [O] | 29.479 | 29.479 | |
| Jonathan S Leff Director - [D] | 0 | 0 | |
| Richard S Levy Director - [D] | 51.000 | 51.000 |
| Insider | Durchschnittlicher Gewinn (%) | Aktien in Besitz |
Split Angepasst |
|---|---|---|---|
| Randall Marshall - | 585.600 | 585.600 | |
| Timothy P Noyes President and CEO, Director - [D] [O] | 0 | 0 | |
| Leonardo Viana Nicacio Chief Medical Officer - [O] | 78.181 | 78.181 | |
| Brendan O'Leary Director - [D] | 1.387.198 | 1.387.198 | |
| Martin Sebastian Olivo Chief Medical Officer - [O] | 14.344 | 14.344 | |
|
Opaleye Management Inc.
10% Owner -
|
45.000 | 45.000 | |
|
Opaleye, L.P.
10% Owner -
|
2.208.472 | 2.208.472 | |
| Gregory D Phelps | 6.666 | ||
|
Pharmstandard International S.A.
10% Owner -
|
1.165.344 | 1.165.344 | |
|
Joint Stock Co Pharmstandard Public
10% Owner -
|
1.165.344 | 1.165.344 | |
| Gregory Sargen Director - [D] | 31.000 | 31.000 | |
|
Helmut Schuhsler
10% Owner -
|
500 | 1.943.059 | |
| Jesse Shefferman CEO and President, Director - [D] [O] | 1.021.832 | 1.021.832 | |
|
Skyline Venture Management IV, LLC
10% Owner -
|
1.432.930 | 1.432.930 | |
|
Skyline Venture Partners Qualified Purchaser Fund IV L P
10% Owner -
|
1.432.930 | 1.432.930 | |
| Michael Edward Solomon Director - [D] | 26.500 | 26.500 | |
|
TVM Life Science Ventures VI GmbH & Co KG
10% Owner -
|
1.943.059 | 1.943.059 | |
|
TVM Life Science Ventures VI LP
10% Owner -
|
500 | 1.943.059 | |
| Toner E. Scott Senior VP of Commercial - [O] | 23.357 | 23.357 | |
| Jacqueline Zummo Chief R&D Officer - [O] | 94.827 | 94.827 |
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Erfolgsbilanz der Insiderkäufe - Kurzfristige Gewinnanalyse
In diesem Abschnitt analysieren wir die Rentabilität jedes ungeplanten Insiderkaufs, der auf dem freien Markt in PRTO / Tidal Trust Iii - Rcn Pareto Strategic Allocation Etf getätigt wurde. Diese Analyse hilft zu verstehen, ob der Insider beständig abnormale Renditen erzielt und es sich lohnt, ihm zu folgen. Diese Analyse bezieht sich auf ein Jahr nach jedem Handel, und die Ergebnisse sind theoretisch .
Die folgende Tabelle zeigt die jüngsten Käufe am offenen Markt, die nicht Teil eines automatischen Handelsplans waren.
Bereinigter Preis ist der splitbereinigte Preis. Bereinigte Aktien sind die um den Split bereinigten Aktien.
Erfolgsbilanz von Insiderverkäufen - Kurzfristige Verlustanalyse
In diesem Abschnitt analysieren wir die kurzfristige Verlustvermeidung jedes ungeplanten Insider-Verkaufs auf dem freien Markt in PRTO / Tidal Trust Iii - Rcn Pareto Strategic Allocation Etf. Ein konsistentes Muster der Verlustvermeidung kann darauf hindeuten, dass zukünftige Verkaufstransaktionen Kursrückgänge vorhersagen können. Diese Analyse bezieht sich auf ein Jahr nach jedem Handel, und die Ergebnisse sind theoretisch .
Die folgende Tabelle zeigt die jüngsten Verkäufe am offenen Markt, die nicht Teil eines automatischen Handelsplans waren.
Bereinigter Preis ist der splitbereinigte Preis. Bereinigte Aktien sind die um den Split bereinigten Aktien.
Transaktionshistorie
Klicken Sie auf das Link-Symbol, um den vollständigen Transaktionsverlauf anzuzeigen. Transaktionen, die im Rahmen eines automatischen Handelsplans 10b5-1 gemeldet werden, sind in der Spalte 10b-5 mit einem X gekennzeichnet.
| Datei Datum |
Handel Datum |
Form | Insider | Ticker | Wertpapier-Titel | Code | Direkt | Ausführung Preis |
Einheit Preis |
Eimheiten Verändert |
Wert Geändert (1K) |
Verbleibende Optionen |
Verbleibende Aktien |
|
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2026-06-03 | 2026-06-02 | 4 | CONKLING WILLIAM | TARA | Common Stock | D | 4,3400 | -6.008 | -26 | 69.992 | ||||
| 2026-04-09 | 2026-04-08 | 4 | Zummo Jacqueline | TARA | Common Stock | D | 5,4000 | -1.134 | -6 | 94.827 | ||||
| 2026-04-02 | 2026-04-01 | 4 | Zummo Jacqueline | TARA | Common Stock | D | 5,2600 | -22.598 | -119 | 95.961 | ||||
| 2026-01-27 | 2026-01-26 | 4 | Zummo Jacqueline | TARA | Common Stock | D | 6,6700 | -3.724 | -25 | 118.559 | ||||
| 2026-01-27 | 2026-01-26 | 4 | Shefferman Jesse | TARA | Common Stock | D | 6,6700 | -8.732 | -58 | 1.021.832 | ||||
| 2026-01-27 | 2026-01-26 | 4 | Fabbio Patrick | TARA | Common Stock | D | 6,6700 | -3.261 | -22 | 64.115 | ||||
| 2026-01-27 | 2026-01-26 | 4 | Fry Hannah | TARA | Common Stock | D | 6,6700 | -1.457 | -10 | 42.723 | ||||
| 2026-01-22 | 2026-01-20 | 4 | Zummo Jacqueline | TARA | Common Stock | D | 5,6000 | -6.578 | -37 | 122.283 | ||||
| 2026-01-22 | 2026-01-20 | 4 | Fry Hannah | TARA | Common Stock | D | 5,6000 | -2.132 | -12 | 44.180 | ||||
| 2026-01-22 | 2026-01-20 | 4 | Fabbio Patrick | TARA | Common Stock | D | 5,6000 | -3.063 | -17 | 67.376 | ||||
| 2026-01-22 | 2026-01-20 | 4 | Shefferman Jesse | TARA | Common Stock | D | 5,6000 | -16.322 | -91 | 1.030.564 | ||||
| 2026-01-21 | 2026-01-16 | 4 | CONKLING WILLIAM | TARA | Common Stock | D | 26.000 | 76.000 | ||||||
| 2026-01-21 | 2026-01-16 | 4 | Shefferman Jesse | TARA | Common Stock | D | 87.000 | 1.046.886 | ||||||
| 2026-01-21 | 2026-01-16 | 4 | Zummo Jacqueline | TARA | Common Stock | D | 30.000 | 128.861 | ||||||
| 2026-01-21 | 2026-01-16 | 4 | Nicacio Leonardo Viana | TARA | Common Stock | D | 26.000 | 78.181 | ||||||
| 2026-01-21 | 2026-01-16 | 4 | Fry Hannah | TARA | Common Stock | D | 9.500 | 46.312 | ||||||
| 2026-01-21 | 2026-01-16 | 4 | Fabbio Patrick | TARA | Common Stock | D | 28.000 | 70.439 | ||||||
| 2025-07-07 | 2025-06-24 | 4 | Shefferman Jesse | TARA | Common Stock | D | -300.000 | 659.886 | ||||||
| 2025-06-30 | 2025-06-27 | 4 | Shefferman Jesse | TARA | Common Stock | D | -3.367 | 959.886 | ||||||
| 2025-06-30 | 2025-06-27 | 4 | Shefferman Jesse | TARA | Common Stock | D | -10.200 | 963.253 | ||||||
| 2025-06-30 | 2025-06-26 | 4 | Shefferman Jesse | TARA | Common Stock | D | -3.400 | 973.453 | ||||||
| 2025-06-30 | 2025-06-26 | 4 | Shefferman Jesse | TARA | Common Stock | D | -1.700 | 976.853 | ||||||
| 2025-06-04 | 2025-06-02 | 4 | CONKLING WILLIAM | TARA | Common Stock | D | 50.000 | 50.000 | ||||||
| 2025-05-19 | 2025-05-14 | 4/A | Levy Richard S | TARA | Common Stock | D | 3,1900 | 20.000 | 64 | 51.000 | ||||
| 2025-05-16 | 2025-05-14 | 4 | Levy Richard S | TARA | Common Stock | D | 3,1900 | 20.000 | 64 | 51.000 | ||||
| 2025-04-17 | 2025-04-15 | 4 | Nicacio Leonardo Viana | TARA | Common Stock | D | 50.000 | 52.181 | ||||||
| 2025-04-17 | 3 | Nicacio Leonardo Viana | TARA | Common Stock | D | 2.181 | ||||||||
| 2025-03-28 | 2025-03-26 | 4 | Zummo Jacqueline | TARA | Common Stock | D | 4,5300 | -21.224 | -96 | 98.861 | ||||
| 2025-01-28 | 2025-01-24 | 4 | Zummo Jacqueline | TARA | Common Stock | D | 24.500 | 126.639 | ||||||
| 2025-01-28 | 2025-01-24 | 4 | Shefferman Jesse | TARA | Common Stock | D | 65.000 | 994.022 | ||||||
| 2025-01-28 | 2025-01-24 | 4 | Fabbio Patrick | TARA | Common Stock | D | 23.500 | 45.500 | ||||||
| 2025-01-28 | 2025-01-24 | 4 | Fry Hannah | TARA | Common Stock | D | 9.500 | 38.942 | ||||||
| 2025-01-23 | 2025-01-21 | 4 | Zummo Jacqueline | TARA | Common Stock | D | 4,7600 | -6.554 | -31 | 95.585 | ||||
| 2025-01-23 | 2025-01-21 | 4 | Fry Hannah | TARA | Common Stock | D | 4,7600 | -2.130 | -10 | 27.312 | ||||
| 2025-01-23 | 2025-01-21 | 4 | Fabbio Patrick | TARA | Common Stock | D | 4,7600 | -3.061 | -15 | 18.939 | ||||
| 2025-01-23 | 2025-01-21 | 4 | Shefferman Jesse | TARA | Common Stock | D | 4,7600 | -15.469 | -74 | 913.553 | ||||
| 2025-01-07 | 2025-01-03 | 4 | Fry Hannah | TARA | Common Stock | D | 6,1400 | -394 | -2 | 29.442 | ||||
| 2025-01-07 | 2025-01-03 | 4 | Zummo Jacqueline | TARA | Common Stock | D | 6,1400 | -2.157 | -13 | 102.139 | ||||
| 2025-01-07 | 2025-01-03 | 4 | Shefferman Jesse | TARA | Common Stock | D | 6,1400 | -6.479 | -40 | 929.022 | ||||
| 2024-09-12 | 2024-09-12 | 4 | Opaleye Management Inc. By Managed account | TARA | Common Stock, par value $0.001 per share | I | 1,7089 | -6.500 | -11 | 45.000 | ||||
| 2024-09-12 | 2024-09-12 | 4 | Opaleye Management Inc. By Opaleye, L.P. | TARA | Common Stock, par value $0.001 per share | I | 1,7089 | -119.801 | -205 | 1.944.134 | ||||
| 2024-09-12 | 2024-09-11 | 4 | Opaleye Management Inc. By Managed account | TARA | Common Stock, par value $0.001 per share | I | 1,7141 | -1.600 | -3 | 51.500 | ||||
| 2024-09-12 | 2024-09-11 | 4 | Opaleye Management Inc. By Opaleye, L.P. | TARA | Common Stock, par value $0.001 per share | I | 1,7141 | -31.000 | -53 | 2.063.935 | ||||
| 2024-09-10 | 2024-09-10 | 4 | Opaleye Management Inc. By Managed account | TARA | Common Stock, par value $0.001 per share | I | 1,7690 | -1.500 | -3 | 53.100 | ||||
| 2024-09-10 | 2024-09-10 | 4 | Opaleye Management Inc. By Opaleye, L.P. | TARA | Common Stock, par value $0.001 per share | I | 1,7690 | -24.000 | -42 | 2.094.935 | ||||
| 2024-09-10 | 2024-09-09 | 4 | Opaleye Management Inc. By Managed account | TARA | Common Stock, par value $0.001 per share | I | 1,8947 | -1.900 | -4 | 54.600 | ||||
| 2024-09-10 | 2024-09-09 | 4 | Opaleye Management Inc. By Opaleye, L.P. | TARA | Common Stock, par value $0.001 per share | I | 1,8947 | -34.592 | -66 | 2.118.935 | ||||
| 2024-08-30 | 2024-08-28 | 4 | Shefferman Jesse | TARA | Common Stock | D | -3.300 | 935.501 | ||||||
| 2024-08-30 | 2024-08-28 | 4 | Shefferman Jesse | TARA | Common Stock | D | -5.263 | 938.801 | ||||||
| 2024-07-18 | 2024-07-16 | 4 | Opaleye Management Inc. By Managed account | TARA | Common Stock, par value $0.001 per share | I | 2,4419 | -3.500 | -9 | 56.500 | ||||
| 2024-07-18 | 2024-07-16 | 4 | Opaleye Management Inc. By Opaleye, L.P. | TARA | Common Stock, par value $0.001 per share | I | 2,4419 | -7.896 | -19 | 2.153.527 | ||||
| 2024-07-11 | 2024-07-11 | 4 | Opaleye Management Inc. By Managed account | TARA | Common Stock, par value $0.001 per share | I | 2,4034 | -15.000 | -36 | 60.000 | ||||
| 2024-07-11 | 2024-07-11 | 4 | Opaleye Management Inc. By Opaleye, L.P. | TARA | Common Stock, par value $0.001 per share | I | 2,4034 | -32.993 | -79 | 2.161.423 | ||||
| 2024-07-11 | 2024-07-10 | 4 | Opaleye Management Inc. By Managed account | TARA | Common Stock, par value $0.001 per share | I | 2,3080 | -5.000 | -12 | 75.000 | ||||
| 2024-07-11 | 2024-07-10 | 4 | Opaleye Management Inc. By Opaleye, L.P. | TARA | Common Stock, par value $0.001 per share | I | 2,3080 | -13.061 | -30 | 2.194.416 | ||||
| 2024-07-11 | 2024-07-09 | 4 | Opaleye Management Inc. By Managed account | TARA | Common Stock, par value $0.001 per share | I | 2,2138 | -2.500 | -6 | 80.000 | ||||
| 2024-07-11 | 2024-07-09 | 4 | Opaleye Management Inc. By Opaleye, L.P. | TARA | Common Stock, par value $0.001 per share | I | 2,2138 | -5.997 | -13 | 2.207.477 | ||||
| 2024-07-03 | 2024-07-01 | 4 | Opaleye Management Inc. By Managed account | TARA | Common Stock, par value $0.001 per share | I | 2,1233 | -2.500 | -5 | 87.500 | ||||
| 2024-07-03 | 2024-07-01 | 4 | Opaleye Management Inc. By Opaleye, L.P. | TARA | Common Stock, par value $0.001 per share | I | 2,1233 | -5.788 | -12 | 2.213.474 | ||||
| 2024-06-28 | 2024-06-28 | 4 | Opaleye Management Inc. By Managed account | TARA | Common Stock, par value $0.001 per share | I | 2,0748 | -5.000 | -10 | 85.000 | ||||
| 2024-06-28 | 2024-06-28 | 4 | Opaleye Management Inc. By Opaleye, L.P. | TARA | Common Stock, par value $0.001 per share | I | 2,0748 | -12.994 | -27 | 2.219.262 | ||||
| 2024-06-28 | 2024-06-27 | 4 | Opaleye Management Inc. By Managed account | TARA | Common Stock, par value $0.001 per share | I | 2,2581 | -12.471 | -28 | 90.000 | ||||
| 2024-06-28 | 2024-06-27 | 4 | Opaleye Management Inc. By Opaleye, L.P. | TARA | Common Stock, par value $0.001 per share | I | 2,2581 | -34.103 | -77 | 2.232.256 | ||||
| 2024-06-27 | 2024-06-25 | 4 | Opaleye Management Inc. By Managed account | TARA | Common Stock, par value $0.001 per share | I | 2,2581 | -6.225 | -14 | 102.471 | ||||
| 2024-06-27 | 2024-06-25 | 4 | Opaleye Management Inc. By Opaleye, L.P. | TARA | Common Stock, par value $0.001 per share | I | 2,2581 | -6.500 | -15 | 2.266.359 | ||||
| 2024-05-31 | 2024-05-31 | 4 | Opaleye Management Inc. By Managed account | TARA | Common Stock, par value $0.001 per share | I | 2,9009 | -5.824 | -17 | 108.696 | ||||
| 2024-05-31 | 2024-05-30 | 4 | Opaleye Management Inc. By Managed account | TARA | Common Stock, par value $0.001 per share | I | 2,9375 | -9.230 | -27 | 114.520 | ||||
| 2024-05-23 | 2024-05-22 | 4 | Opaleye Management Inc. By Managed account | TARA | Common Stock, par value $0.001 per share | I | 3,0021 | -500 | -2 | 123.750 | ||||
| 2024-05-23 | 2024-05-22 | 4 | Opaleye Management Inc. By Managed account | TARA | Common Stock, par value $0.001 per share | I | 3,0210 | -9.300 | -28 | 2.272.859 | ||||
| 2024-05-23 | 2024-05-21 | 4 | Opaleye Management Inc. By Managed account | TARA | Common Stock, par value $0.001 per share | I | 3,0557 | -1.800 | -6 | 124.250 | ||||
| 2024-05-23 | 2024-05-21 | 4 | Opaleye Management Inc. By Opaleye, L.P. | TARA | Common Stock, par value $0.001 per share | I | 3,0557 | -31.200 | -95 | 2.282.159 | ||||
| 2024-05-17 | 2024-05-17 | 4 | Opaleye Management Inc. By Managed account | TARA | Common Stock, par value $0.001 per share | I | 3,0606 | -1.200 | -4 | 126.050 | ||||
| 2024-05-17 | 2024-05-17 | 4 | Opaleye Management Inc. By Managed account | TARA | Common Stock, par value $0.001 per share | I | 3,3281 | -2.750 | -9 | 127.250 | ||||
| 2024-05-17 | 2024-05-17 | 4 | Opaleye Management Inc. By Opaleye, L.P. | TARA | Common Stock, par value $0.001 per share | I | 3,0606 | -19.685 | -60 | 2.313.359 | ||||
| 2024-05-17 | 2024-05-17 | 4 | Opaleye Management Inc. By Opaleye, L.P. | TARA | Common Stock, par value $0.001 per share | I | 3,3281 | -47.250 | -157 | 2.333.044 | ||||
| 2024-05-10 | 2024-05-10 | 4 | Opaleye Management Inc. By Opaleye, L.P. | TARA | Common Stock, par value $0.001 per share | I | 3,1142 | -151.700 | -472 | 2.380.294 | ||||
| 2024-05-10 | 2024-05-09 | 4 | Opaleye Management Inc. By Opaleye, L.P. | TARA | Common Stock, par value $0.001 per share | I | 3,0891 | -30.600 | -95 | 2.531.994 | ||||
| 2024-01-23 | 2024-01-19 | 4 | Fry Hannah | TARA | Common Stock | D | 1,9100 | -904 | -2 | 29.836 | ||||
| 2024-01-23 | 2024-01-19 | 4 | Fry Hannah | TARA | Common Stock | D | 8.000 | 30.740 | ||||||
| 2024-01-23 | 2024-01-19 | 4 | Fabbio Patrick | TARA | Common Stock | D | 22.000 | 22.000 | ||||||
| 2024-01-23 | 2024-01-19 | 4 | Zummo Jacqueline | TARA | Common Stock | D | 1,9100 | -3.049 | -6 | 104.296 | ||||
| 2024-01-23 | 2024-01-19 | 4 | Zummo Jacqueline | TARA | Common Stock | D | 23.000 | 107.345 | ||||||
| 2024-01-23 | 2024-01-19 | 4 | Bandari Jathin | TARA | Common Stock | D | 1,9100 | -2.879 | -5 | 56.704 | ||||
| 2024-01-23 | 2024-01-19 | 4 | Bandari Jathin | TARA | Common Stock | D | 23.000 | 59.583 | ||||||
| 2024-01-23 | 2024-01-19 | 4 | Shefferman Jesse | TARA | Common Stock | D | 1,9100 | -7.803 | -15 | 944.064 | ||||
| 2024-01-23 | 2024-01-19 | 4 | Shefferman Jesse | TARA | Common Stock | D | 59.000 | 951.867 | ||||||
| 2024-01-12 | 2024-01-10 | 4 | Bandari Jathin | TARA | Common Stock | D | 2,3900 | -1.877 | -4 | 36.583 | ||||
| 2024-01-12 | 2024-01-10 | 4 | Zummo Jacqueline | TARA | Common Stock | D | 2,3900 | -5.229 | -12 | 84.345 | ||||
| 2024-01-12 | 2024-01-10 | 4 | Shefferman Jesse | TARA | Common Stock | D | 2,3900 | -5.746 | -14 | 892.867 | ||||
| 2024-01-05 | 2024-01-03 | 4 | Zummo Jacqueline | TARA | Common Stock | D | 2,1700 | -1.899 | -4 | 89.574 | ||||
| 2024-01-05 | 2024-01-03 | 4 | Shefferman Jesse | TARA | Common Stock | D | 2,1700 | -5.840 | -13 | 898.613 | ||||
| 2024-01-05 | 2024-01-03 | 4 | Fry Hannah | TARA | Common Stock | D | 2,1700 | -324 | -1 | 22.740 | ||||
| 2023-07-18 | 2023-07-17 | 4 | Fry Hannah | TARA | Common Stock | D | 2,5600 | -10.075 | -26 | 23.064 | ||||
| 2023-07-05 | 2023-07-03 | 4 | Bandari Jathin | TARA | Common Stock | D | 2,4600 | -682 | -2 | 38.460 | ||||
| 2023-06-27 | 2023-06-27 | 4 | Shefferman Jesse | TARA | Common Stock | D | -7.420 | 904.453 | ||||||
| 2023-06-27 | 2023-06-23 | 4 | Shefferman Jesse | TARA | Common Stock | D | -1.890 | 911.873 | ||||||
| 2023-02-10 | 2022-06-27 | 5 | Shefferman Jesse | TARA | Common Stock | D | -4.519 | 913.763 | ||||||
| 2023-01-20 | 2023-01-19 | 4 | Bandari Jathin | TARA | Common Stock | D | 20.700 | 39.142 | ||||||
| 2023-01-20 | 2023-01-19 | 4 | Zummo Jacqueline | TARA | Common Stock | D | 19.900 | 91.473 | ||||||
| 2023-01-20 | 2023-01-19 | 4 | Fry Hannah | TARA | Common Stock | D | 5.900 | 33.139 | ||||||
| 2023-01-20 | 2023-01-19 | 4 | Shefferman Jesse | TARA | Common Stock | D | 51.300 | 918.282 | ||||||
| 2023-01-11 | 2023-01-10 | 4 | Zummo Jacqueline | TARA | Common Stock | D | 3,0000 | -5.225 | -16 | 71.573 | ||||
| 2023-01-11 | 2023-01-10 | 4 | Bandari Jathin | TARA | Common Stock | D | 3,0000 | -1.876 | -6 | 18.442 | ||||
| 2023-01-11 | 2023-01-10 | 4 | Shefferman Jesse | TARA | Common Stock | D | 3,0000 | -5.855 | -18 | 866.982 | ||||
| 2023-01-04 | 2023-01-03 | 4 | Zummo Jacqueline | TARA | Common Stock | D | 2,8000 | -2.159 | -6 | 76.798 | ||||
| 2023-01-04 | 2023-01-03 | 4 | Shefferman Jesse | TARA | Common Stock | D | 2,8000 | -6.604 | -18 | 872.837 | ||||
| 2023-01-04 | 2023-01-03 | 4 | Fry Hannah | TARA | Common Stock | D | 2,8000 | -361 | -1 | 27.239 | ||||
| 2022-12-30 | 2022-12-30 | 4 | Opaleye Management Inc. By Managed Account | TARA | Common Stock, par value $0.001 per share | I | 2,7111 | 2.300 | 6 | 130.000 | ||||
| 2022-12-30 | 2022-12-30 | 4 | Opaleye Management Inc. By Opaleye, L.P. | TARA | Common Stock, par value $0.001 per share | I | 2,7111 | 13.173 | 36 | 2.562.594 | ||||
| 2022-09-15 | 2022-09-15 | 4 | Opaleye Management Inc. By Managed Account | TARA | Common Stock, par value $0.001 per share | I | 3,8000 | 2.300 | 9 | 132.300 | ||||
| 2022-09-15 | 2022-09-15 | 4 | Opaleye Management Inc. By Opaleye, L.P. | TARA | Common Stock, par value $0.001 per share | I | 3,8000 | 5.000 | 19 | 2.575.777 | ||||
| 2022-09-15 | 2022-09-14 | 4 | Opaleye Management Inc. By Managed Account | TARA | Common Stock, par value $0.001 per share | I | 3,9800 | 2.500 | 10 | 130.000 | ||||
| 2022-09-15 | 2022-09-14 | 4 | Opaleye Management Inc. By Opaleye, L.P. | TARA | Common Stock, par value $0.001 per share | I | 3,9800 | 14.100 | 56 | 2.570.777 | ||||
| 2022-08-15 | 2022-08-11 | 4 | Shefferman Jesse | TARA | Common Stock | D | 3,8400 | 9.065 | 35 | 879.441 | ||||
| 2022-07-19 | 2022-07-15 | 4 | Davis Blaine | TARA | Common Stock | D | 3,1300 | -5.081 | -16 | 20.662 | ||||
| 2022-07-19 | 2022-07-16 | 4 | Fry Hannah | TARA | Common Stock | D | 25.000 | 27.600 | ||||||
| 2022-07-19 | 3 | Fry Hannah | TARA | Common Stock | D | 2.600 | ||||||||
| 2022-07-05 | 2022-06-30 | 4 | BESHAR LUKE M | TARA | Common Stock | D | 3,1000 | 10.000 | 31 | 198.000 | ||||
| 2022-07-05 | 2022-07-01 | 4 | Bandari Jathin | TARA | Common Stock | D | 3,2200 | -682 | -2 | 20.318 | ||||
| 2022-04-15 | 2022-04-08 | 4/A | Opaleye Management Inc. By Managed Account | TARA | Common Stock, par value $0.001 per share | I | 4,7958 | 2.469 | 12 | 127.500 | ||||
| 2022-04-15 | 2022-04-08 | 4/A | Opaleye Management Inc. By Opaleye, L.P. | TARA | Common Stock, par value $0.001 per share | I | 4,7958 | 5.322 | 26 | 2.556.667 | ||||
| 2022-04-15 | 2022-04-07 | 4/A | Opaleye Management Inc. By Managed Account | TARA | Common Stock, par value $0.001 per share | I | 4,7432 | 1.000 | 5 | 125.031 | ||||
| 2022-04-15 | 2022-04-07 | 4/A | Opaleye Management Inc. By Opaleye, L.P. | TARA | Common Stock, par value $0.001 per share | I | 4,7432 | 1.345 | 6 | 2.551.345 | ||||
| 2022-04-08 | 2022-04-08 | 4 | Opaleye Management Inc. By Managed Account | TARA | Common Stock, par value $0.001 per share | I | 4,7958 | 2.469 | 12 | 128 | ||||
| 2022-04-08 | 2022-04-08 | 4 | Opaleye Management Inc. By Opaleye, L.P. | TARA | Common Stock, par value $0.001 per share | I | 4,7958 | 5.322 | 26 | 2.556.667 | ||||
| 2022-04-08 | 2022-04-07 | 4 | Opaleye Management Inc. By Managed Account | TARA | Common Stock, par value $0.001 per share | I | 4,7432 | 1.000 | 5 | 125.031 | ||||
| 2022-04-08 | 2022-04-07 | 4 | Opaleye Management Inc. By Opaleye, L.P. | TARA | Common Stock, par value $0.001 per share | I | 4,7432 | 1.345 | 6 | 2.551.345 | ||||
| 2022-03-16 | 2022-03-14 | 4 | BESHAR LUKE M | TARA | Common Stock | D | 4,2500 | 10.000 | 42 | 188.000 | ||||
| 2022-03-14 | 2022-03-10 | 4 | BESHAR LUKE M | TARA | Common Stock | D | 4,4555 | 10.000 | 45 | 178.000 | ||||
| 2022-02-11 | 2021-06-29 | 5 | Shefferman Jesse | TARA | Common Stock | D | -513 | 870.376 | ||||||
| 2022-02-11 | 2021-06-29 | 5 | Shefferman Jesse | TARA | Common Stock | D | -1.536 | 870.889 | ||||||
| 2022-01-31 | 2022-01-28 | 4 | Opaleye Management Inc. By Managed Account | TARA | Common Stock, par value $0.001 per share | I | 4,9632 | 4.031 | 20 | 124.031 | ||||
| 2022-01-31 | 2022-01-28 | 4 | Opaleye Management Inc. By Opaleye, L.P. | TARA | Common Stock, par value $0.001 per share | I | 4,9632 | 20.000 | 99 | 2.550.000 | ||||
| 2022-01-12 | 2022-01-10 | 4 | Zummo Jacqueline | TARA | Common Stock | D | 6,2700 | -4.603 | -29 | 78.957 | ||||
| 2022-01-12 | 2022-01-10 | 4 | Shefferman Jesse | TARA | Common Stock | D | 6,2700 | -5.080 | -32 | 872.425 | ||||
| 2022-01-12 | 2022-01-10 | 4 | Bandari Jathin | TARA | Stock Option (Right to Buy) | D | 6,27 | 81.000 | 81.000 | |||||
| 2022-01-12 | 2022-01-10 | 4 | Bandari Jathin | TARA | Common Stock | D | 13.500 | 13.500 | ||||||
| 2022-01-12 | 3 | Bandari Jathin | TARA | Common Stock | D | 7.500 | ||||||||
| 2022-01-05 | 2022-01-03 | 4 | Shefferman Jesse | TARA | Stock Option (Right to Buy) | D | 6,90 | 253.500 | 253.500 | |||||
| 2022-01-05 | 2022-01-03 | 4 | Shefferman Jesse | TARA | Common Stock | D | 42.300 | 877.505 | ||||||
| 2022-01-05 | 2022-01-03 | 4 | Zummo Jacqueline | TARA | Stock Option (Right to Buy) | D | 6,90 | 84.800 | 84.800 | |||||
| 2022-01-05 | 2022-01-03 | 4 | Zummo Jacqueline | TARA | Common Stock | D | 14.100 | 83.560 | ||||||
| 2022-01-05 | 2022-01-03 | 4 | Davis Blaine | TARA | Stock Option (Right to Buy) | D | 6,90 | 84.800 | 84.800 | |||||
| 2022-01-05 | 2022-01-03 | 4 | Davis Blaine | TARA | Common Stock | D | 14.100 | 15.581 | ||||||
| 2021-12-29 | 2021-12-29 | 4 | Opaleye Management Inc. By Managed Account | TARA | Common Stock, par value $0.001 per share | I | 6,9795 | 4.500 | 31 | 120.000 | ||||
| 2021-12-29 | 2021-12-28 | 4 | Opaleye Management Inc. By Managed Account | TARA | Common Stock, par value $0.001 per share | I | 6,3588 | 5.500 | 35 | 115.500 | ||||
| 2021-12-29 | 2021-12-28 | 4 | Opaleye Management Inc. By Opaleye, L.P. | TARA | Common Stock, par value $0.001 per share | I | 6,3588 | 1.591 | 10 | 2.530.000 | ||||
| 2021-12-27 | 2021-12-27 | 4 | Opaleye Management Inc. By Managed Account | TARA | Common Stock, par value $0.001 per share | I | 6,5317 | 5.000 | 33 | 110.000 | ||||
| 2021-12-27 | 2021-12-27 | 4 | Opaleye Management Inc. By Opaleye, L.P. | TARA | Common Stock, par value $0.001 per share | I | 6,5317 | 31.700 | 207 | 2.528.409 | ||||
| 2021-12-27 | 2021-12-23 | 4 | Opaleye Management Inc. By Managed Account | TARA | Common Stock, par value $0.001 per share | I | 6,6000 | 800 | 5 | 105.000 | ||||
| 2021-12-27 | 2021-12-23 | 4 | Opaleye Management Inc. By Opaleye, L.P. | TARA | Common Stock, par value $0.001 per share | I | 6,6000 | 500 | 3 | 2.496.709 | ||||
| 2021-12-22 | 2021-12-20 | 4 | Opaleye Management Inc. By Opaleye, L.P. | TARA | Common Stock, par value $0.001 per share | I | 6,4900 | 703 | 5 | 2.496.209 | ||||
| 2021-12-20 | 2021-12-17 | 4 | Opaleye Management Inc. By Managed Account | TARA | Common Stock, par value $0.001 per share | I | 6,6000 | 490 | 3 | 104.200 | ||||
| 2021-12-20 | 2021-12-17 | 4 | Opaleye Management Inc. By Opaleye, L.P. | TARA | Common Stock, par value $0.001 per share | I | 6,6000 | 2.300 | 15 | 2.495.506 | ||||
| 2021-12-20 | 2021-12-16 | 4 | Opaleye Management Inc. By Managed Account | TARA | Common Stock, par value $0.001 per share | I | 6,4108 | 1.063 | 7 | 103.710 | ||||
| 2021-12-20 | 2021-12-16 | 4 | Opaleye Management Inc. By Opaleye, L.P. | TARA | Common Stock, par value $0.001 per share | I | 6,4108 | 6.500 | 42 | 2.493.206 | ||||
| 2021-11-19 | 2021-11-18 | 4 | Opaleye Management Inc. By Managed Account | TARA | Common Stock, par value $0.001 per share | I | 6,9795 | 1.000 | 7 | 102.647 | ||||
| 2021-11-19 | 2021-11-18 | 4 | Opaleye Management Inc. By Opaleye, L.P. | TARA | Common Stock, par value $0.001 per share | I | 6,9795 | 14.206 | 99 | 2.486.706 | ||||
| 2021-11-19 | 2021-11-17 | 4 | Opaleye Management Inc. By Managed Account | TARA | Common Stock, par value $0.001 per share | I | 6,9800 | 1.090 | 8 | 101.647 | ||||
| 2021-11-19 | 2021-11-17 | 4 | Opaleye Management Inc. By Opaleye, L.P. | TARA | Common Stock, par value $0.001 per share | I | 6,9800 | 8.028 | 56 | 2.472.500 | ||||
| 2021-11-08 | 2021-11-04 | 4 | Opaleye Management Inc. By Managed Account | TARA | Common Stock, par value $0.001 per share | I | 6,5000 | 557 | 4 | 100.557 | ||||
| 2021-11-08 | 2021-11-04 | 4 | Opaleye Management Inc. By Opaleye, L.P. | TARA | Common Stock, par value $0.001 per share | I | 6,5000 | 6.000 | 39 | 2.464.472 | ||||
| 2021-06-14 | 2021-06-10 | 4 | Olivo Martin Sebastian | TARA | Common Stock | D | 10,1300 | 4.934 | 50 | 14.344 | ||||
| 2021-06-14 | 2021-06-10 | 4 | Olivo Martin Sebastian | TARA | Common Stock | D | 10,0800 | 4.959 | 50 | 9.410 | ||||
| 2021-06-10 | 2021-06-09 | 4 | Huang Jane | TARA | Stock Option (Right to Buy) | D | 10,51 | 10.000 | 10.000 | |||||
| 2021-06-10 | 2021-06-09 | 4 | Huang Jane | TARA | Stock Option (Right to Buy) | D | 10,51 | 20.000 | 20.000 | |||||
| 2021-06-10 | 2021-06-09 | 4 | Flannelly Barry P | TARA | Stock Option (Right to Buy) | D | 10,51 | 10.000 | 10.000 | |||||
| 2021-06-10 | 2021-06-09 | 4 | Smith Cynthia | TARA | Stock Option (Right to Buy) | D | 10,51 | 10.000 | 10.000 | |||||
| 2021-06-10 | 2021-06-09 | 4 | Levy Richard S | TARA | Stock Option (Right to Buy) | D | 10,51 | 10.000 | 10.000 | |||||
| 2021-06-10 | 2021-06-09 | 4 | Solomon Michael Edward | TARA | Stock Option (Right to Buy) | D | 10,51 | 10.000 | 10.000 | |||||
| 2021-06-10 | 2021-06-09 | 4 | SARGEN GREGORY | TARA | Stock Option (Right to Buy) | D | 10,51 | 10.000 | 10.000 | |||||
| 2021-06-10 | 2021-06-09 | 4 | GARCEAU ROGER | TARA | Stock Option (Right to Buy) | D | 10,51 | 10.000 | 10.000 | |||||
| 2021-06-10 | 2021-06-09 | 4 | BESHAR LUKE M | TARA | Stock Option (Right to Buy) | D | 10,51 | 10.000 | 10.000 | |||||
| 2021-04-20 | 2021-04-19 | 4 | Olivo Martin Sebastian | TARA | Stock Option (Right to Buy) | D | 15,30 | 120.000 | 120.000 | |||||
| 2021-04-20 | 3 | Olivo Martin Sebastian | TARA | Common Stock | D | 4.451 | ||||||||
| 2021-02-01 | 2021-01-29 | 4 | Smith Cynthia | TARA | Stock Option (Right to Buy) | D | 17,98 | 3.750 | 21.750 | |||||
| 2021-02-01 | 2021-01-29 | 4 | Smith Cynthia | TARA | Stock Option (Right to Buy) | D | 17,98 | 18.000 | 18.000 | |||||
| 2021-01-21 | 2021-01-19 | 4 | Davis Blaine | TARA | Stock Option (Right to Buy) | D | 19,82 | 75.000 | 75.000 | |||||
| 2021-01-21 | 2021-01-19 | 4 | Zummo Jacqueline | TARA | Stock Option (Right to Buy) | D | 19,82 | 75.000 | 75.000 | |||||
| 2021-01-21 | 2021-01-19 | 4 | Shefferman Jesse | TARA | Stock Option (Right to Buy) | D | 19,82 | 202.000 | 202.000 | |||||
| 2021-01-13 | 2021-01-11 | 4 | Zummo Jacqueline | TARA | Common Stock | D | 21,1600 | -4.653 | -98 | 69.460 | ||||
| 2021-01-13 | 2021-01-11 | 4 | Shefferman Jesse | TARA | Common Stock | D | 21,1600 | -5.069 | -107 | 835.205 | ||||
| 2020-10-02 | 2020-09-30 | 4 | Opaleye Management Inc. By Opaleye, L.P. | TARA | Common Stock, par value $0.001 per share | I | 16,0000 | 50.000 | 800 | 2.458.472 | ||||
| 2020-09-25 | 2020-09-24 | 4 | Opaleye Management Inc. By Opaleye, L.P. | "TARA" | Common Stock, par value $0.001 per share | I | 16,8700 | 200.000 | 3.374 | 2.408.472 | ||||
| 2020-09-25 | 2020-09-24 | 4 | Opaleye Management Inc. By Managed Account | "TARA" | Common Stock, par value $0.001 per share | I | 16,8700 | 100.000 | 1.687 | 100.000 | ||||
| 2020-09-23 | 2020-09-22 | 4 | Davis Blaine | TARA | Common Stock | D | 16,9060 | 1.481 | 25 | 1.481 | ||||
| 2020-09-15 | 2020-09-14 | 4 | Marshall Randall | TARA | Common Stock | D | 20,0000 | -474 | -9 | 585.600 | ||||
| 2020-09-15 | 2020-09-14 | 4 | Marshall Randall | TARA | Common Stock | D | 19,2600 | -2.080 | -40 | 586.074 | ||||
| 2020-09-14 | 2020-09-10 | 4 | Marshall Randall | TARA | Common Stock | D | 18,0000 | -239 | -4 | 588.154 | ||||
| 2020-09-10 | 2020-09-09 | 4 | Marshall Randall | TARA | Common Stock | D | 19,2700 | -4.913 | -95 | 588.393 | ||||
| 2020-09-10 | 2020-09-09 | 4 | Marshall Randall | TARA | Common Stock | D | 18,1000 | -5.309 | -96 | 593.306 | ||||
| 2020-09-10 | 2020-09-08 | 4 | Marshall Randall | TARA | Common Stock | D | 18,9400 | -3.108 | -59 | 598.615 | ||||
| 2020-09-04 | 2020-09-03 | 4 | Marshall Randall | TARA | Common Stock | D | 20,1900 | -52 | -1 | 601.723 | ||||
| 2020-09-04 | 2020-09-02 | 4 | Marshall Randall | TARA | Common Stock | D | 20,6800 | -207 | -4 | 601.775 | ||||
| 2020-09-01 | 2020-08-28 | 4 | Marshall Randall | TARA | Common Stock | D | 22,0900 | -771 | -17 | 601.982 | ||||
| 2020-08-28 | 2020-08-27 | 4 | Marshall Randall | TARA | Common Stock | D | 22,3700 | -616 | -14 | 602.753 | ||||
| 2020-08-28 | 2020-08-26 | 4 | Marshall Randall | TARA | Common Stock | D | 22,4000 | -1.418 | -32 | 603.369 | ||||
| 2020-08-26 | 2020-08-25 | 4 | Marshall Randall | TARA | Common Stock | D | 22,7300 | -2.461 | -56 | 604.787 | ||||
| 2020-08-26 | 2020-08-24 | 4 | Marshall Randall | TARA | Common Stock | D | 23,1600 | -974 | -23 | 607.248 | ||||
| 2020-08-24 | 2020-08-20 | 4 | Marshall Randall | TARA | Common Stock | D | 24,1830 | -510 | -12 | 608.222 | ||||
| 2020-08-20 | 2020-08-18 | 4 | Marshall Randall | TARA | Common Stock | D | 25,1900 | -200 | -5 | 608.732 | ||||
| 2020-08-18 | 2020-08-17 | 4 | Marshall Randall | TARA | Common Stock | D | 25,1100 | -1.548 | -39 | 608.932 | ||||
| 2020-08-18 | 2020-08-14 | 4 | Marshall Randall | TARA | Common Stock | D | 25,0900 | -700 | -18 | 610.480 | ||||
| 2020-07-31 | 2020-07-30 | 4 | Marshall Randall | TARA | Common Stock | D | 26,1400 | -1.317 | -34 | 611.180 | ||||
| 2020-07-31 | 2020-07-29 | 4 | Marshall Randall | TARA | Common Stock | D | 28,4500 | -100 | -3 | 612.497 | ||||
| 2020-07-31 | 2020-07-29 | 4 | Marshall Randall | TARA | Common Stock | D | 27,2800 | -600 | -16 | 612.597 | ||||
| 2020-07-31 | 2020-07-29 | 4 | Marshall Randall | TARA | Common Stock | D | 26,0300 | -1.816 | -47 | 613.197 | ||||
| 2020-07-29 | 2020-07-28 | 4 | Marshall Randall | TARA | Common Stock | D | 35,4500 | -600 | -21 | 615.013 | ||||
| 2020-07-29 | 2020-07-28 | 4 | Marshall Randall | TARA | Common Stock | D | 33,7900 | -1.650 | -56 | 615.613 | ||||
| 2020-07-29 | 2020-07-28 | 4 | Marshall Randall | TARA | Common Stock | D | 33,0900 | -1.200 | -40 | 617.263 | ||||
| 2020-07-29 | 2020-07-28 | 4 | Marshall Randall | TARA | Common Stock | D | 31,5300 | -3.493 | -110 | 618.463 | ||||
| 2020-07-29 | 2020-07-28 | 4 | Marshall Randall | TARA | Common Stock | D | 30,4200 | -14.243 | -433 | 621.956 | ||||
| 2020-07-29 | 2020-07-28 | 4 | Marshall Randall | TARA | Common Stock | D | 28,6300 | -1.811 | -52 | 636.199 | ||||
| 2020-07-29 | 2020-07-28 | 4 | Marshall Randall | TARA | Common Stock | D | 26,8500 | -2.600 | -70 | 638.010 | ||||
| 2020-07-29 | 2020-07-27 | 4 | Marshall Randall | TARA | Common Stock | D | 26,0800 | -338 | -9 | 640.610 | ||||
| 2020-07-27 | 2020-07-23 | 4 | Flannelly Barry P | TARA | Stock Option (Right to Buy) | D | 26,70 | 8.250 | 26.250 | |||||
| 2020-07-27 | 2020-07-23 | 4 | Flannelly Barry P | TARA | Stock Option (Right to Buy) | D | 26,70 | 18.000 | 18.000 | |||||
| 2020-07-27 | 2020-07-24 | 4 | Marshall Randall | TARA | Common Stock | D | 26,0000 | -300 | -8 | 640.948 | ||||
| 2020-07-27 | 2020-07-23 | 4 | Marshall Randall | TARA | Common Stock | D | 27,2900 | -93 | -3 | 641.248 | ||||
| 2020-07-27 | 2020-07-23 | 4 | Marshall Randall | TARA | Common Stock | D | 26,5800 | -1.950 | -52 | 641.341 | ||||
| 2020-07-23 | 2020-07-22 | 4 | Marshall Randall | TARA | Common Stock | D | 27,4450 | -75 | -2 | 643.291 | ||||
| 2020-07-23 | 2020-07-22 | 4 | Marshall Randall | TARA | Common Stock | D | 26,6900 | -1.297 | -35 | 643.366 | ||||
| 2020-07-23 | 2020-07-21 | 4 | Marshall Randall | TARA | Common Stock | D | 26,5600 | -223 | -6 | 644.663 | ||||
| 2020-07-21 | 2020-07-20 | 4 | Marshall Randall | TARA | Common Stock | D | 27,6800 | -472 | -13 | 644.886 | ||||
| 2020-07-21 | 2020-07-20 | 4 | Marshall Randall | TARA | Common Stock | D | 26,7000 | -2.257 | -60 | 645.358 | ||||
| 2020-07-21 | 2020-07-17 | 4 | Marshall Randall | TARA | Common Stock | D | 26,6600 | -1.601 | -43 | 647.615 | ||||
| 2020-07-14 | 2020-07-13 | 4 | Marshall Randall | TARA | Common Stock | D | 27,1300 | -2.145 | -58 | 649.216 | ||||
| 2020-07-14 | 2020-07-10 | 4 | Marshall Randall | TARA | Common Stock | D | 27,4100 | -2.659 | -73 | 651.361 | ||||
| 2020-07-13 | 2020-07-10 | 4 | Shefferman Jesse | TARA | Stock Option (Right to Buy) | D | 27,42 | 111.250 | 111.250 | |||||
| 2020-06-11 | 2020-01-09 | 4/A | BESHAR LUKE M | TARA | Stock Option (Right to Buy) | D | 9,18 | 6.676 | 6.676 | |||||
| 2020-06-11 | 2020-01-09 | 4/A | BESHAR LUKE M | TARA | Stock Option (Right to Buy) | D | 9,18 | 12.399 | 12.399 | |||||
| 2020-06-11 | 2020-01-09 | 4/A | Braunstein Scott | TARA | Stock Option (Right to Buy) | D | 9,18 | 15.641 | 15.641 | |||||
| 2020-06-11 | 2020-01-09 | 4/A | Braunstein Scott | TARA | Stock Option (Right to Buy) | D | 9,18 | 16.214 | 16.214 | |||||
| 2020-06-11 | 2020-01-09 | 4/A | Braunstein Scott | TARA | Stock Option (Right to Buy) | D | 9,18 | 2.861 | 2.861 | |||||
| 2020-06-11 | 2020-01-09 | 4/A | GARCEAU ROGER | TARA | Stock Option (Right to Buy) | D | 9,18 | 12.399 | 12.399 | |||||
| 2020-06-11 | 2020-01-10 | 4/A | Solomon Michael Edward | TARA | Common Stock | D | 26.500 | 26.500 | ||||||
| 2020-06-11 | 2020-01-09 | 4/A | Solomon Michael Edward | TARA | Stock Option (Right to Buy) | D | 9,18 | 6.676 | 6.676 | |||||
| 2020-06-11 | 2020-01-09 | 4/A | Solomon Michael Edward | TARA | Stock Option (Right to Buy) | D | 9,18 | 2.861 | 2.861 | |||||
| 2020-06-11 | 2020-06-09 | 4 | Solomon Michael Edward | TARA | Stock Option (Right to Buy) | D | 35,00 | 9.000 | 9.000 | |||||
| 2020-06-11 | 2020-06-09 | 4 | SARGEN GREGORY | TARA | Stock Option (Right to Buy) | D | 35,00 | 9.000 | 9.000 | |||||
| 2020-06-11 | 2020-06-09 | 4 | Levy Richard S | TARA | Stock Option (Right to Buy) | D | 35,00 | 9.000 | 9.000 | |||||
| 2020-06-11 | 2020-06-09 | 4 | Braunstein Scott | TARA | Stock Option (Right to Buy) | D | 35,00 | 9.000 | 9.000 | |||||
| 2020-06-11 | 2020-06-09 | 4 | GARCEAU ROGER | TARA | Stock Option (Right to Buy) | D | 35,00 | 9.000 | 9.000 | |||||
| 2020-06-11 | 2020-06-09 | 4 | BESHAR LUKE M | TARA | Stock Option (Right to Buy) | D | 35,00 | 9.000 | 9.000 | |||||
| 2020-02-18 | 2020-01-10 | 4/A | Shefferman Jesse | TARA | Stock Option (Right to Buy) | D | 30,00 | 111.250 | 111.250 | |||||
| 2020-02-11 | 2020-02-11 | 4 | Davis Blaine | TARA | Stock Option (Right to Buy) | D | 37,30 | 94.000 | 94.000 | |||||
| 2020-01-13 | 2020-01-10 | 4 | Zummo Jacqueline | TARA | Common Stock | D | 45.500 | 74.113 | ||||||
| 2020-01-13 | 2020-01-09 | 4 | Zummo Jacqueline | TARA | Stock Option (Right to Buy) | D | 9,18 | 9.537 | 9.537 | |||||
| 2020-01-13 | 2020-01-09 | 4 | Zummo Jacqueline | TARA | Stock Option (Right to Buy) | D | 9,18 | 9.537 | 9.537 | |||||
| 2020-01-13 | 2020-01-09 | 4 | Zummo Jacqueline | TARA | Stock Option (Right to Buy) | D | 9,18 | 19.075 | 19.075 | |||||
| 2020-01-13 | 2020-01-09 | 4 | Zummo Jacqueline | TARA | Common Stock | D | 28.613 | 28.613 | ||||||
| 2020-01-13 | 2020-01-10 | 4 | Levy Richard S | TARA | Common Stock | D | 31.000 | 31.000 | ||||||
| 2020-01-13 | 2020-01-10 | 4 | Solomon Michael Edward | TARA | Common Stock | D | 26.500 | 26.500 | ||||||
| 2020-01-13 | 2020-01-09 | 4 | Solomon Michael Edward | TARA | Stock Option (Right to Buy) | D | 9,18 | 10.491 | 10.491 | |||||
| 2020-01-13 | 2020-01-09 | 4 | Solomon Michael Edward | TARA | Stock Option (Right to Buy) | D | 9,18 | 6.676 | 6.676 | |||||
| 2020-01-13 | 2020-01-09 | 4 | Solomon Michael Edward | TARA | Stock Option (Right to Buy) | D | 9,18 | 2.861 | 2.861 | |||||
| 2020-01-13 | 2020-01-09 | 4 | Solomon Michael Edward | TARA | Stock Option (Right to Buy) | D | 9,18 | 9.537 | 9.537 | |||||
| 2020-01-13 | 2020-01-10 | 4 | GARCEAU ROGER | TARA | Common Stock | D | 33.000 | 33.000 | ||||||
| 2020-01-13 | 2020-01-09 | 4 | GARCEAU ROGER | TARA | Stock Option (Right to Buy) | D | 9,18 | 10.491 | 10.491 | |||||
| 2020-01-13 | 2020-01-09 | 4 | GARCEAU ROGER | TARA | Stock Option (Right to Buy) | D | 9,18 | 12.399 | 12.399 | |||||
| 2020-01-13 | 2020-01-10 | 4 | SARGEN GREGORY | TARA | Common Stock | D | 31.000 | 31.000 | ||||||
| 2020-01-13 | 2020-01-10 | 4 | Braunstein Scott | TARA | Common Stock | D | 26.500 | 26.500 | ||||||
| 2020-01-13 | 2020-01-09 | 4 | Braunstein Scott | TARA | Stock Option (Right to Buy) | D | 9,18 | 15.737 | 15.737 | |||||
| 2020-01-13 | 2020-01-09 | 4 | Braunstein Scott | TARA | Stock Option (Right to Buy) | D | 9,18 | 6.676 | 6.676 | |||||
| 2020-01-13 | 2020-01-09 | 4 | Braunstein Scott | TARA | Stock Option (Right to Buy) | D | 9,18 | 9.537 | 9.537 | |||||
| 2020-01-13 | 2020-01-09 | 4 | Braunstein Scott | TARA | Stock Option (Right to Buy) | D | 9,18 | 9.537 | 9.537 | |||||
| 2020-01-13 | 2020-01-09 | 4 | Braunstein Scott | TARA | Stock Option (Right to Buy) | D | 9,18 | 2.861 | 2.861 | |||||
| 2020-01-13 | 2020-01-10 | 4 | Shefferman Jesse | TARA | Stock Option (Right to Buy) | D | 31,50 | 111.250 | 111.250 | |||||
| 2020-01-13 | 2020-01-10 | 4 | Shefferman Jesse | TARA | Common Stock | D | 50.000 | 840.274 | ||||||
| 2020-01-13 | 2020-01-09 | 4 | Shefferman Jesse | TARA | Common Stock | D | 790.274 | 790.274 | ||||||
| 2020-01-13 | 2020-01-09 | 4 | Marshall Randall | TARA | Common Stock | D | 654.020 | 654.020 | ||||||
| 2020-01-13 | 2020-01-10 | 4 | Casoy Julio | TARA | Common Stock | D | 45.500 | 45.500 | ||||||
| 2020-01-13 | 2020-01-09 | 4 | Casoy Julio | TARA | Stock Option (Right to Buy) | D | 9,18 | 38.151 | 38.151 | |||||
| 2020-01-13 | 3 | Opaleye, L.P. | TARA | Common Stock | D | 9.206 | ||||||||
| 2020-01-13 | 3 | Opaleye, L.P. | TARA | Common Stock | D | 9.206 | ||||||||
| 2020-01-13 | 3 | Opaleye, L.P. | TARA | Common Stock | D | 9.206 | ||||||||
| 2020-01-13 | 2020-01-09 | 4 | Opaleye, L.P. | TARA | Common Stock | D | 7,0100 | 1.426.234 | 9.998 | 2.208.472 | ||||
| 2020-01-13 | 2020-01-09 | 4 | Opaleye, L.P. | TARA | Common Stock | D | 777.635 | 782.238 | ||||||
| 2020-01-13 | 2020-01-10 | 4 | BESHAR LUKE M | TARA | Common Stock | D | 168.000 | 168.000 | ||||||
| 2020-01-13 | 2020-01-09 | 4 | BESHAR LUKE M | TARA | Stock Option (Right to Buy) | D | 9,18 | 10.491 | 10.491 | |||||
| 2020-01-13 | 2020-01-09 | 4 | BESHAR LUKE M | TARA | Stock Option (Right to Buy) | D | 9,18 | 6.676 | 6.676 | |||||
| 2020-01-13 | 2020-01-09 | 4 | BESHAR LUKE M | TARA | Stock Option (Right to Buy) | D | 9,18 | 12.399 | 12.399 | |||||
| 2019-11-14 | 2019-11-12 | 4 | Abingworth LLP | PRTO | Series A Convertible Preferred Stock | I | 0,99 | -126 | 2.400 | |||||
| 2019-11-14 | 2019-11-12 | 4 | Abingworth LLP | PRTO | Common Stock, $0.001 par value | I | 0,9949 | 126.645 | 126 | 2.144.517 | ||||
| 2019-11-14 | 2019-11-12 | 4 | Haines Timothy By Abingworth Bioventures VI, LP | PRTO | Series A Convertible Preferred Stock | I | 0,99 | -126 | 2.400 | |||||
| 2019-11-14 | 2019-11-12 | 4 | Haines Timothy By Abingworth Bioventures VI, LP | PRTO | Common Stock, $0.001 par value | I | 0,9949 | 126.645 | 126 | 2.144.517 | ||||
| 2019-11-12 | 2019-11-08 | 4 | Freund John Gordon | PRTO | Series A Convertible Preferred Stock | I | 0,99 | -700 | 354 | |||||
| 2019-11-12 | 2019-11-08 | 4 | Freund John Gordon | PRTO | Common Stock | D | 0,9949 | 703.588 | 700 | 2.175.882 | ||||
| 2019-03-18 | 2019-03-15 | 4 | Burke Steven Keith | PRTO | Common Stock | I | 7.333 | 26.332 | ||||||
| 2019-03-18 | 2019-03-15 | 4 | Burke Steven Keith | PRTO | Common Stock | I | 7.333 | 26.332 | ||||||
| 2019-03-18 | 2019-03-15 | 4 | Burke Steven Keith | PRTO | Common Stock | D | -7.333 | 101.917 | ||||||
| 2019-03-18 | 2019-03-15 | 4 | Burke Steven Keith | PRTO | Common Stock | D | -7.333 | 101.917 | ||||||
| 2019-03-18 | 2019-03-15 | 4 | Burke Steven Keith | PRTO | Common Stock | D | -7.334 | 116.584 | ||||||
| 2019-02-04 | 2019-01-31 | 4 | NOYES TIMOTHY P | PRTO | Stock Option (Right to Buy) | D | 2,70 | 350.000 | 350.000 | |||||
| 2019-01-23 | 2019-01-18 | 4 | Burke Steven Keith | PRTO | Stock Option (Right to Buy) | D | 2,64 | 145.000 | 145.000 | |||||
| 2019-01-23 | 2019-01-18 | 4 | Eldridge, George Arthur | PRTO | Stock Option (Right to Buy) | D | 2,64 | 145.000 | 145.000 | |||||
| 2019-01-23 | 2019-01-18 | 4 | Hartman Bradley J | PRTO | Stock Option (Right to Buy) | D | 2,64 | 70.000 | 70.000 | |||||
| 2019-01-23 | 2019-01-18 | 4 | Kowalsky Matthew Paul | PRTO | Stock Option (Right to Buy) | D | 2,64 | 60.000 | 60.000 | |||||
| 2019-01-23 | 2019-01-18 | 4 | Toner E. Scott | PRTO | Stock Option (Right to Buy) | D | 2,64 | 60.000 | 60.000 | |||||
| 2019-01-23 | 2019-01-18 | 4 | Gottlieb Daniel Philip | PRTO | Stock Option (Right to Buy) | D | 2,64 | 60.000 | 60.000 | |||||
| 2019-01-03 | 2018-12-31 | 4 | Burke Steven Keith | PRTO | Common Stock | D | 1,9300 | 2.448 | 5 | 123.917 | ||||
| 2019-01-03 | 2018-12-31 | 4 | Eldridge, George Arthur | PRTO | Common Stock | D | 1,9300 | 2.448 | 5 | 29.132 | ||||
| 2019-01-03 | 2018-12-31 | 4 | Kowalsky Matthew Paul | PRTO | Common Stock | D | 1,9300 | 2.448 | 5 | 29.479 | ||||
| 2019-01-03 | 2018-12-31 | 4 | Toner E. Scott | PRTO | Common Stock | D | 1,9300 | 4.117 | 8 | 23.357 | ||||
| 2018-08-02 | 2018-08-01 | 4 | Hartman Bradley J | PRTO | Stock Option (Right to Buy) | D | 2,12 | 150.000 | 150.000 | |||||
| 2018-07-03 | 2018-06-29 | 4 | Burke Steven Keith | PRTO | Common Stock | D | 1,6150 | -10.000 | -16 | 121.469 | ||||
| 2018-07-03 | 2018-06-29 | 4 | Eldridge, George Arthur | PRTO | Common Stock | D | 1,6150 | 10.000 | 16 | 26.684 | ||||
| 2018-07-03 | 2018-06-29 | 4 | Kowalsky Matthew Paul | PRTO | Common Stock | D | 1,6150 | 10.000 | 16 | 27.031 | ||||
| 2018-07-03 | 2018-06-29 | 4 | Toner E. Scott | PRTO | Common Stock | D | 1,6150 | 4.856 | 8 | 19.240 | ||||
| 2018-06-12 | 2018-06-08 | 4 | Flynn James E Through Deerfield Management Company, L.P. | PRTO | Stock Option (Right to Buy) | I | 2,50 | 12.700 | 12.700 | |||||
| 2018-06-12 | 2018-06-08 | 4 | LEFF JONATHAN S | PRTO | Stock Option (Right to Buy) | D | 2,50 | 12.700 | 12.700 | |||||
| 2018-06-11 | 2018-06-08 | 4 | Abingworth LLP By affiliate | PRTO | Stock Option (Right to Buy) | I | 2,50 | 12.700 | 12.700 | |||||
| 2018-06-11 | 2018-06-08 | 4 | Birner Hubert | PRTO | Stock Option (Right to Buy) | D | 2,50 | 12.700 | 12.700 | |||||
| 2018-06-11 | 2018-06-08 | 4 | BOHLIN GAREN G | PRTO | Stock Option (Right to Buy) | D | 2,50 | 12.700 | 12.700 | |||||
| 2018-06-11 | 2018-06-08 | 4 | Canute Scott A | PRTO | Stock Option (Right to Buy) | D | 2,50 | 12.700 | 12.700 | |||||
| 2018-06-11 | 2018-06-08 | 4 | Freund John Gordon | PRTO | Stock Option (Right to Buy) | D | 2,50 | 12.700 | 12.700 | |||||
| 2018-06-11 | 2018-06-08 | 4 | Haines Timothy | PRTO | Stock Option (Right to Buy) | D | 2,50 | 12.700 | 12.700 | |||||
| 2018-06-11 | 2018-06-08 | 4 | HASTINGS PAUL J | PRTO | Stock Option (Right to Buy) | D | 2,50 | 12.700 | 12.700 | |||||
| 2018-06-11 | 2018-06-08 | 4 | Kingsley Stuart A | PRTO | Stock Option (Right to Buy) | D | 2,50 | 12.700 | 12.700 | |||||
| 2018-02-20 | 2018-02-16 | 4 | NOYES TIMOTHY P | PRTO | Common Stock | D | 2,1100 | -2.997 | -6 | 0 | ||||
| 2018-02-16 | 2018-02-15 | 4 | NOYES TIMOTHY P | PRTO | Common Stock | D | 2,1520 | -2.245 | -5 | 2.997 | ||||
| 2018-02-16 | 2018-02-14 | 4 | NOYES TIMOTHY P | PRTO | Common Stock | D | 2,2000 | -3.500 | -8 | 5.242 | ||||
| 2018-02-09 | 2018-02-08 | 4 | NOYES TIMOTHY P | PRTO | Stock Option (Right to Buy) | D | 2,15 | 500.000 | 500.000 | |||||
| 2018-01-18 | 2018-01-17 | 4 | Burke Steven Keith | PRTO | Stock Option (Right to Buy) | D | 2,85 | 200.000 | 200.000 | |||||
| 2018-01-18 | 2018-01-17 | 4 | Eldridge, George Arthur | PRTO | Stock Option (Right to Buy) | D | 2,85 | 200.000 | 200.000 | |||||
| 2018-01-18 | 2018-01-17 | 4 | Gottlieb Daniel Philip | PRTO | Stock Option (Right to Buy) | D | 2,85 | 110.000 | 110.000 | |||||
| 2018-01-18 | 2018-01-17 | 4 | Kowalsky Matthew Paul | PRTO | Stock Option (Right to Buy) | D | 2,85 | 110.000 | 110.000 | |||||
| 2018-01-18 | 2018-01-17 | 4 | Toner E. Scott | PRTO | Stock Option (Right to Buy) | D | 2,85 | 110.000 | 110.000 | |||||
| 2018-01-17 | 2018-01-16 | 4 | NOYES TIMOTHY P | PRTO | Common Stock | D | 2,3570 | -10.000 | -24 | 8.742 | ||||
| 2018-01-03 | 2017-12-29 | 4 | Burke Steven Keith | PRTO | Common Stock | D | 1,2960 | -3.934 | -5 | 111.469 | ||||
| 2018-01-03 | 2017-12-29 | 4 | Eldridge, George Arthur | PRTO | Common Stock | D | 1,2960 | 3.934 | 5 | 16.684 | ||||
| 2018-01-03 | 2017-12-29 | 4 | Kowalsky Matthew Paul | PRTO | Common Stock | D | 1,2960 | 3.934 | 5 | 17.031 | ||||
| 2018-01-03 | 2017-12-29 | 4 | Toner E. Scott | PRTO | Common Stock | D | 1,2960 | 5.531 | 7 | 14.384 | ||||
| 2017-12-18 | 2017-12-15 | 4 | Burke Steven Keith | PRTO | Common Stock | I | 3.333 | 11.666 | ||||||
| 2017-12-18 | 2017-12-15 | 4 | Burke Steven Keith | PRTO | Common Stock | I | 3.333 | 11.666 | ||||||
| 2017-12-18 | 2017-12-15 | 4 | Burke Steven Keith | PRTO | Common Stock | D | -3.333 | 107.535 | ||||||
| 2017-12-18 | 2017-12-15 | 4 | Burke Steven Keith | PRTO | Common Stock | D | -3.333 | 107.535 | ||||||
| 2017-12-18 | 2017-12-15 | 4 | Burke Steven Keith | PRTO | Common Stock | D | -3.334 | 114.201 | ||||||
| 2017-12-18 | 2017-12-15 | 4 | Burke Steven Keith | PRTO | Common Stock | D | 1,8800 | 12.000 | 23 | 117.535 | ||||
| 2017-12-15 | 2017-12-14 | 4 | NOYES TIMOTHY P | PRTO | Common Stock | D | 1,8540 | -10.000 | -19 | 18.742 | ||||
| 2017-12-04 | 2017-11-30 | 4 | Flynn James E Through Deerfield International Master Fund, L.P. | PRTO | Common Stock | I | 1,7500 | -110.557 | -193 | 0 | ||||
| 2017-12-04 | 2017-11-30 | 4 | Flynn James E Through Deerfield Partners, L.P. | PRTO | Common Stock | I | 1,7500 | 110.557 | 193 | 197.424 | ||||
| 2017-11-16 | 2017-11-15 | 4 | NOYES TIMOTHY P | PRTO | Common Stock | D | 1,7020 | -5.650 | -10 | 28.742 | ||||
| 2017-11-16 | 2017-11-14 | 4 | NOYES TIMOTHY P | PRTO | Common Stock | D | 1,6870 | -4.350 | -7 | 34.392 | ||||
| 2017-11-14 | 2017-11-14 | 4 | BOHLIN GAREN G | PRTO | Common Stock | D | 1,8890 | 3.812 | 7 | 53.312 | ||||
| 2017-11-14 | 2017-11-13 | 4 | BOHLIN GAREN G | PRTO | Common Stock | D | 1,9180 | 25.700 | 49 | 49.500 | ||||
| 2017-11-14 | 2017-11-10 | 4 | BOHLIN GAREN G | PRTO | Common Stock | D | 1,9630 | 23.800 | 47 | 23.800 | ||||
| 2017-11-14 | 2017-11-14 | 4 | Eldridge, George Arthur As custodian for child's UTMA account | PRTO | Common Stock | I | 1,6900 | 295 | 0 | 1.545 | ||||
| 2017-10-17 | 2017-10-16 | 4 | NOYES TIMOTHY P | PRTO | Common Stock | D | 2,3120 | -10.000 | -23 | 38.742 | ||||
| 2017-09-18 | 2017-09-15 | 4 | NOYES TIMOTHY P | PRTO | Common Stock | D | 1,4790 | -5.146 | -8 | 48.742 | ||||
| 2017-09-18 | 2017-09-14 | 4 | NOYES TIMOTHY P | PRTO | Common Stock | D | 1,4540 | -4.854 | -7 | 53.888 | ||||
| 2017-08-04 | 3 | Flynn James E Through Deerfield International Master Fund, L.P. | PRTO | Common Stock | I | 1.335.456 | ||||||||
| 2017-08-04 | 3 | Flynn James E Through Deerfield Partners, L.P. | PRTO | Common Stock | I | 1.311.766 | ||||||||
| 2017-08-04 | 3 | Flynn James E Through Deerfield International Master Fund, L.P. | PRTO | Common Stock | I | 1.335.456 | ||||||||
| 2017-08-04 | 3 | Flynn James E Through Deerfield Partners, L.P. | PRTO | Common Stock | I | 1.311.766 | ||||||||
| 2017-08-04 | 3 | Flynn James E Through Deerfield Private Design Fund III, L.P. | PRTO | Common Stock | I | 2.102.698 | ||||||||
| 2017-08-04 | 3 | Flynn James E Through Deerfield Special Situations Fund, L.P. | PRTO | Common Stock | I | 1.374.575 | ||||||||
| 2017-08-04 | 3 | Flynn James E Through Deerfield International Master Fund, L.P. | PRTO | Common Stock | I | 1.335.456 | ||||||||
| 2017-08-04 | 3 | Flynn James E Through Deerfield Partners, L.P. | PRTO | Common Stock | I | 1.311.766 | ||||||||
| 2017-08-04 | 3 | Flynn James E Through Deerfield Private Design Fund III, L.P. | PRTO | Common Stock | I | 2.102.698 | ||||||||
| 2017-08-04 | 3 | Flynn James E Through Deerfield Private Design Fund III, L.P. | PRTO | Common Stock | I | 2.102.698 | ||||||||
| 2017-08-04 | 3 | Flynn James E Through Deerfield Special Situations Fund, L.P. | PRTO | Common Stock | I | 1.374.575 | ||||||||
| 2017-08-04 | 3 | Flynn James E Through Deerfield Partners, L.P. | PRTO | Common Stock | I | 1.311.766 | ||||||||
| 2017-08-04 | 3 | Flynn James E Through Deerfield Partners, L.P. | PRTO | Common Stock | I | 1.311.766 | ||||||||
| 2017-08-04 | 3 | Flynn James E Through Deerfield Private Design Fund III, L.P. | PRTO | Common Stock | I | 2.102.698 | ||||||||
| 2017-08-04 | 3 | Flynn James E Through Deerfield Partners, L.P. | PRTO | Common Stock | I | 1.311.766 | ||||||||
| 2017-08-04 | 3 | Flynn James E Through Deerfield International Master Fund, L.P. | PRTO | Common Stock | I | 1.335.456 | ||||||||
| 2017-08-04 | 3 | Flynn James E Through Deerfield Private Design Fund III, L.P. | PRTO | Common Stock | I | 2.102.698 | ||||||||
| 2017-08-04 | 3 | Flynn James E Through Deerfield Private Design Fund III, L.P. | PRTO | Common Stock | I | 2.102.698 | ||||||||
| 2017-08-04 | 3 | Flynn James E Through Deerfield Partners, L.P. | PRTO | Common Stock | I | 1.311.766 | ||||||||
| 2017-08-04 | 3 | Flynn James E Through Deerfield International Master Fund, L.P. | PRTO | Common Stock | I | 1.335.456 | ||||||||
| 2017-08-04 | 3 | Flynn James E Through Deerfield Private Design Fund III, L.P. | PRTO | Common Stock | I | 2.102.698 | ||||||||
| 2017-08-04 | 3 | Flynn James E Through Deerfield Partners, L.P. | PRTO | Common Stock | I | 1.311.766 | ||||||||
| 2017-08-04 | 3 | Flynn James E Through Deerfield International Master Fund, L.P. | PRTO | Common Stock | I | 1.335.456 | ||||||||
| 2017-08-04 | 3 | Flynn James E Through Deerfield Special Situations Fund, L.P. | PRTO | Common Stock | I | 1.374.575 | ||||||||
| 2017-08-04 | 3 | Flynn James E Through Deerfield Private Design Fund III, L.P. | PRTO | Common Stock | I | 2.102.698 | ||||||||
| 2017-08-04 | 3 | Flynn James E Through Deerfield Private Design Fund III, L.P. | PRTO | Common Stock | I | 2.102.698 | ||||||||
| 2017-08-04 | 3 | Flynn James E Through Deerfield International Master Fund, L.P. | PRTO | Common Stock | I | 1.335.456 | ||||||||
| 2017-08-04 | 3 | Flynn James E Through Deerfield Special Situations Fund, L.P. | PRTO | Common Stock | I | 1.374.575 | ||||||||
| 2017-08-04 | 3 | Flynn James E Through Deerfield Partners, L.P. | PRTO | Common Stock | I | 1.311.766 | ||||||||
| 2017-08-04 | 3 | Flynn James E Through Deerfield International Master Fund, L.P. | PRTO | Common Stock | I | 1.335.456 | ||||||||
| 2017-08-04 | 3 | Flynn James E Through Deerfield Special Situations Fund, L.P. | PRTO | Common Stock | I | 1.374.575 | ||||||||
| 2017-08-04 | 3 | Flynn James E Through Deerfield Private Design Fund III, L.P. | PRTO | Common Stock | I | 2.102.698 | ||||||||
| 2017-08-04 | 3 | Flynn James E Through Deerfield International Master Fund, L.P. | PRTO | Common Stock | I | 1.335.456 | ||||||||
| 2017-08-04 | 3 | Flynn James E Through Deerfield Special Situations Fund, L.P. | PRTO | Common Stock | I | 1.374.575 | ||||||||
| 2017-08-04 | 3 | Flynn James E Through Deerfield Private Design Fund III, L.P. | PRTO | Common Stock | I | 2.102.698 | ||||||||
| 2017-08-04 | 3 | Flynn James E Through Deerfield International Master Fund, L.P. | PRTO | Common Stock | I | 1.335.456 | ||||||||
| 2017-08-04 | 3 | Flynn James E Through Deerfield Special Situations Fund, L.P. | PRTO | Common Stock | I | 1.374.575 | ||||||||
| 2017-08-04 | 3 | Flynn James E Through Deerfield Special Situations Fund, L.P. | PRTO | Common Stock | I | 1.374.575 | ||||||||
| 2017-08-04 | 3 | Flynn James E Through Deerfield Partners, L.P. | PRTO | Common Stock | I | 1.311.766 | ||||||||
| 2017-08-04 | 3 | Flynn James E Through Deerfield International Master Fund, L.P. | PRTO | Common Stock | I | 1.335.456 | ||||||||
| 2017-08-04 | 3 | Flynn James E Through Deerfield Special Situations Fund, L.P. | PRTO | Common Stock | I | 1.374.575 | ||||||||
| 2017-08-04 | 3 | Flynn James E Through Deerfield Special Situations Fund, L.P. | PRTO | Common Stock | I | 1.374.575 | ||||||||
| 2017-08-04 | 3 | Flynn James E Through Deerfield Special Situations Fund, L.P. | PRTO | Common Stock | I | 1.374.575 | ||||||||
| 2017-08-04 | 3 | Flynn James E Through Deerfield Partners, L.P. | PRTO | Common Stock | I | 1.311.766 | ||||||||
| 2017-08-04 | 3 | LEFF JONATHAN S | PRTO | Common Stock | D | 0 | ||||||||
| 2017-08-04 | 2017-08-02 | 4 | Flynn James E Through Deerfield Management Company, L.P. | PRTO | Stock Option (Right to Buy) | I | 1,30 | 13.333 | 13.333 | |||||
| 2017-08-04 | 2017-08-02 | 4 | LEFF JONATHAN S | PRTO | Stock Option (Right to Buy) | D | 1,30 | 13.333 | 13.333 | |||||
| 2017-07-05 | 2017-06-30 | 4 | Burke Steven Keith | PRTO | Common Stock | D | 1,2960 | -10.000 | -13 | 105.535 | ||||
| 2017-07-05 | 2017-06-30 | 4 | Eldridge, George Arthur | PRTO | Common Stock | D | 1,2960 | 10.000 | 13 | 12.750 | ||||
| 2017-07-05 | 2017-06-30 | 4 | Kowalsky Matthew Paul | PRTO | Common Stock | D | 1,2960 | 10.000 | 13 | 13.097 | ||||
| 2017-07-05 | 2017-06-30 | 4 | Toner E. Scott | PRTO | Common Stock | D | 1,2960 | -8.718 | -11 | 8.853 | ||||
| 2017-06-30 | 2017-06-22 | 4/A | TVM Life Science Ventures VI GmbH & Co KG | PRTO | Series A Convertible Preferred Stock | D | 0,99 | 1.000,0000 | 372 | 372 | 500 | |||
| 2017-06-26 | 2017-06-22 | 4 | TVM Life Science Ventures VI GmbH & Co KG | PRTO | Series A Convertible Preferred Stock | D | 0,99 | 1.000,0000 | 128 | 128 | 500 | |||
| 2017-06-26 | 2017-06-22 | 4 | TVM Life Science Ventures VI GmbH & Co KG | PRTO | Series A Convertible Preferred Stock | D | 0,99 | 1.000,0000 | 372 | 372 | 500 | |||
| 2017-06-26 | 2017-06-22 | 4 | Freund John Gordon By Skyline Venture Partners | PRTO | Series A Convertible Preferred Stock | I | 0,99 | 1.000,0000 | 1.054 | 1.054 | 1.054 | |||
| 2017-06-26 | 2017-06-22 | 4 | Haines Timothy By Abingworth Bioventures VI, LP | PRTO | Series A Convertible Preferred Stock | I | 0,99 | 1.000,0000 | 2.526 | 2.526 | 2.526 | |||
| 2017-06-26 | 2017-06-22 | 4 | Abingworth LLP | PRTO | Series A Convertible Preferred Stock | I | 0,99 | 1.000,0000 | 2.526 | 2.526 | 2.526 | |||
| 2017-06-21 | 2017-06-20 | 4 | Canute Scott A | PRTO | Stock Option (Right to Buy) | D | 1,30 | 6.666 | 6.666 | |||||
| 2017-06-21 | 2017-06-20 | 4 | HASTINGS PAUL J | PRTO | Stock Option (Right to Buy) | D | 1,30 | 6.666 | 6.666 | |||||
| 2017-06-21 | 2017-06-20 | 4 | Kingsley Stuart A | PRTO | Stock Option (Right to Buy) | D | 1,30 | 6.666 | 6.666 | |||||
| 2017-06-21 | 2017-06-20 | 4 | Abingworth LLP By affiliate | PRTO | Stock Option (Right to Buy) | I | 1,30 | 6.666 | 6.666 | |||||
| 2017-06-21 | 2017-06-20 | 4 | Birner Hubert | PRTO | Stock Option (Right to Buy) | D | 1,30 | 6.666 | 6.666 | |||||
| 2017-06-21 | 2017-06-20 | 4 | Freund John Gordon | PRTO | Stock Option (Right to Buy) | D | 1,30 | 6.666 | 6.666 | |||||
| 2017-06-21 | 2017-06-20 | 4 | Haines Timothy | PRTO | Stock Option (Right to Buy) | D | 1,30 | 6.666 | 6.666 | |||||
| 2017-06-21 | 2017-06-20 | 4 | BOHLIN GAREN G | PRTO | Stock Option (Right to Buy) | D | 1,30 | 6.666 | 6.666 | |||||
| 2017-05-05 | 3 | Kowalsky Matthew Paul | PRTO | Common Stock, $0.001 par value | D | 6.194 | ||||||||
| 2017-05-05 | 3 | Kowalsky Matthew Paul | PRTO | Common Stock, $0.001 par value | D | 6.194 | ||||||||
| 2017-03-13 | 2017-03-10 | 4 | Burke Steven Keith | PRTO | Stock Option (Right to Buy) | D | 1,27 | -57.934 | 0 | |||||
| 2017-03-13 | 2017-03-10 | 4 | Burke Steven Keith | PRTO | Stock Option (Right to Buy) | D | 2,38 | -12.287 | 0 | |||||
| 2017-03-13 | 2017-03-10 | 4 | Burke Steven Keith | PRTO | Common Stock | D | 1,2700 | 57.934 | 74 | 95.535 | ||||
| 2017-03-13 | 2017-03-10 | 4 | Burke Steven Keith | PRTO | Common Stock | D | 2,3800 | 12.287 | 29 | 37.601 | ||||
| 2017-01-26 | 2017-01-24 | 4 | NOYES TIMOTHY P | PRTO | Stock Option (Right to Buy) | D | 2,05 | 122.838 | 122.838 | |||||
| 2017-01-26 | 2017-01-24 | 4 | Gottlieb Daniel Philip | PRTO | Stock Option (Right to Buy) | D | 2,05 | 29.215 | 29.215 | |||||
| 2017-01-26 | 2017-01-24 | 4 | Burke Steven Keith | PRTO | Stock Option (Right to Buy) | D | 2,05 | 53.119 | 53.119 | |||||
| 2017-01-26 | 2017-01-24 | 4 | Eldridge, George Arthur | PRTO | Stock Option (Right to Buy) | D | 2,05 | 53.119 | 53.119 | |||||
| 2017-01-26 | 2017-01-24 | 4 | Toner E. Scott | PRTO | Stock Option (Right to Buy) | D | 2,05 | 73.039 | 73.039 | |||||
| 2016-12-06 | 2016-12-02 | 4 | Burke Steven Keith | PRTO | Common Stock | I | 2.500 | 5.000 | ||||||
| 2016-12-06 | 2016-12-02 | 4 | Burke Steven Keith | PRTO | Common Stock | I | 2.500 | 5.000 | ||||||
| 2016-12-06 | 2016-12-02 | 4 | Burke Steven Keith | PRTO | Common Stock | D | -2.500 | 25.314 | ||||||
| 2016-12-06 | 2016-12-02 | 4 | Burke Steven Keith | PRTO | Common Stock | D | -2.500 | 25.314 | ||||||
| 2016-12-06 | 2016-12-02 | 4 | Burke Steven Keith | PRTO | Common Stock | D | -2.500 | 25.314 | ||||||
| 2016-10-20 | 3 | HASTINGS PAUL J | PRTO | Common Stock, $0.001 par value | I | 13.272 | ||||||||
| 2016-10-20 | 3 | HASTINGS PAUL J | PRTO | Common Stock, $0.001 par value | I | 13.272 | ||||||||
| 2016-10-20 | 2016-10-18 | 4 | HASTINGS PAUL J | PRTO | Stock Option (Right to Buy) | D | 9,00 | 13.333 | 13.333 | |||||
| 2016-09-01 | 2016-08-31 | 4 | Toner E. Scott | PRTO | Common Stock | D | -50 | 135 | ||||||
| 2016-06-15 | 2016-06-09 | 4 | Birner Hubert | PRTO | Stock Option (Right to Buy) | D | 5,90 | 6.666 | 6.666 | |||||
| 2016-06-14 | 2016-06-09 | 4 | Canute Scott A | PRTO | Stock Option (Right to Buy) | D | 5,90 | 6.666 | 6.666 | |||||
| 2016-06-14 | 2016-06-09 | 4 | BOHLIN GAREN G | PRTO | Stock Option (Right to Buy) | D | 5,90 | 6.666 | 6.666 | |||||
| 2016-06-14 | 2016-06-09 | 4 | Freund John Gordon | PRTO | Stock Option (Right to Buy) | D | 5,90 | 6.666 | 6.666 | |||||
| 2016-06-14 | 2016-06-09 | 4 | Kingsley Stuart A | PRTO | Stock Option (Right to Buy) | D | 5,90 | 6.666 | 6.666 | |||||
| 2016-06-14 | 2016-06-09 | 4 | Abingworth LLP By affiliate | PRTO | Stock Option (Right to Buy) | I | 5,90 | 6.666 | 6.666 | |||||
| 2016-06-14 | 2016-06-09 | 4 | O'Leary Brendan | PRTO | Stock Option (Right to Buy) | D | 5,90 | 6.666 | 6.666 | |||||
| 2016-06-14 | 2016-06-09 | 4 | Haines Timothy | PRTO | Stock Option (Right to Buy) | D | 5,90 | 6.666 | 6.666 | |||||
| 2016-06-07 | 2016-06-06 | 4 | Eldridge, George Arthur As custodian for child's UTMA account | PRTO | Common Stock | I | 5,7800 | 400 | 2 | 400 | ||||
| 2016-06-07 | 2016-06-06 | 4 | Eldridge, George Arthur As custodian for child's UTMA account | PRTO | Common Stock | I | 5,7760 | 425 | 2 | 425 | ||||
| 2016-06-07 | 2016-06-06 | 4 | Eldridge, George Arthur As custodian for child's UTMA account | PRTO | Common Stock | I | 5,7600 | 425 | 2 | 425 | ||||
| 2016-06-07 | 2016-06-06 | 4 | Eldridge, George Arthur | PRTO | Common Stock | D | 5,7800 | 2.750 | 16 | 2.750 | ||||
| 2016-04-13 | 2016-04-12 | 4 | NOYES TIMOTHY P | PRTO | Stock Option (Right to Buy) | D | 1,91 | -58.742 | 0 | |||||
| 2016-04-13 | 2016-04-12 | 4 | NOYES TIMOTHY P | PRTO | Common Stock | D | 1,9100 | 58.742 | 112 | 58.742 | ||||
| 2016-01-05 | 2015-12-31 | 4 | Toner E. Scott | PRTO | Common Stock | D | 13,1800 | 185 | 2 | 185 | ||||
| 2016-01-05 | 2015-12-31 | 4 | Gottlieb Daniel Philip | PRTO | Common Stock | D | 13,1800 | 244 | 3 | 244 | ||||
| 2016-01-05 | 2016-01-04 | 4 | NOYES TIMOTHY P | PRTO | Stock Option (Right to Buy) | D | 1,91 | -5.000 | 58.742 | |||||
| 2016-01-05 | 2016-01-04 | 4 | NOYES TIMOTHY P | PRTO | Common Stock | D | 13,8800 | -5.000 | -69 | 0 | ||||
| 2016-01-05 | 2016-01-04 | 4 | NOYES TIMOTHY P | PRTO | Common Stock | D | 1,9100 | 5.000 | 10 | 5.000 | ||||
| 2015-12-10 | 2015-12-08 | 4 | Toner E. Scott | PRTO | Stock Option (Right to Buy) | D | 14,70 | -22.000 | 22.000 | |||||
| 2015-12-10 | 2015-12-08 | 4 | NOYES TIMOTHY P | PRTO | Stock Option (Right to Buy) | D | 14,70 | -125.000 | 125.000 | |||||
| 2015-12-10 | 2015-12-08 | 4 | Gottlieb Daniel Philip | PRTO | Stock Option (Right to Buy) | D | 14,70 | -22.000 | 22.000 | |||||
| 2015-12-10 | 2015-12-08 | 4 | Eldridge, George Arthur | PRTO | Stock Option (Right to Buy) | D | 14,70 | -33.000 | 33.000 | |||||
| 2015-12-10 | 2015-12-08 | 4 | Burke Steven Keith | PRTO | Stock Option (Right to Buy) | D | 14,70 | -57.000 | 57.000 | |||||
| 2015-12-02 | 2015-12-01 | 4 | NOYES TIMOTHY P | PRTO | Stock Option (Right to Buy) | D | 1,91 | -5.000 | 63.742 | |||||
| 2015-12-02 | 2015-12-01 | 4 | NOYES TIMOTHY P | PRTO | Common Stock | D | 14,9700 | -5.000 | -75 | 0 | ||||
| 2015-12-02 | 2015-12-01 | 4 | NOYES TIMOTHY P | PRTO | Common Stock | D | 1,9100 | 5.000 | 10 | 5.000 | ||||
| 2015-11-03 | 2015-11-02 | 4 | NOYES TIMOTHY P | PRTO | Stock Option (Right to Buy) | D | 1,91 | -5.000 | 68.742 | |||||
| 2015-11-03 | 2015-11-02 | 4 | NOYES TIMOTHY P | PRTO | Common Stock | D | 13,5000 | -5.000 | -68 | 0 | ||||
| 2015-11-03 | 2015-11-02 | 4 | NOYES TIMOTHY P | PRTO | Common Stock | D | 1,9100 | 5.000 | 10 | 5.000 | ||||
| 2015-10-19 | 2015-10-16 | 4 | Kingsley Stuart A | PRTO | Stock Option (Right to Buy) | D | 15,21 | 13.333 | 13.333 | |||||
| 2015-10-02 | 2015-10-01 | 4 | NOYES TIMOTHY P | PRTO | Stock Option (Right to Buy) | D | 1,91 | -5.000 | 73.742 | |||||
| 2015-10-02 | 2015-10-01 | 4 | NOYES TIMOTHY P | PRTO | Common Stock | D | 13,3300 | -5.000 | -67 | 0 | ||||
| 2015-10-02 | 2015-10-01 | 4 | NOYES TIMOTHY P | PRTO | Common Stock | D | 1,9100 | 5.000 | 10 | 5.000 | ||||
| 2015-09-10 | 2015-09-08 | 4 | NOYES TIMOTHY P | PRTO | Stock Option (Right to Buy) | D | 1,91 | -5.000 | 78.742 | |||||
| 2015-09-10 | 2015-09-08 | 4 | NOYES TIMOTHY P | PRTO | Common Stock | D | 13,5500 | -5.000 | -68 | 0 | ||||
| 2015-09-10 | 2015-09-08 | 4 | NOYES TIMOTHY P | PRTO | Common Stock | D | 1,9100 | 5.000 | 10 | 5.000 | ||||
| 2015-07-23 | 2015-07-21 | 4 | Canute Scott A | PRTO | Stock Option (Right to Buy) | D | 18,25 | 13.333 | 13.333 | |||||
| 2015-07-08 | 2015-06-30 | 4 | Burke Steven Keith | PRTO | Common Stock | D | 8,8400 | 2.403 | 21 | 32.814 | ||||
| 2015-07-08 | 2015-07-07 | 4 | Gottlieb Daniel Philip | PRTO | Common Stock | D | 16,8600 | -1.965 | -33 | 0 | ||||
| 2015-07-08 | 2015-06-30 | 4 | Gottlieb Daniel Philip | PRTO | Common Stock | D | 8,8400 | 1.965 | 17 | 1.965 | ||||
| 2015-06-03 | 2015-06-02 | 4 | BOHLIN GAREN G | PRTO | Stock Option (Right to Buy) | D | 17,59 | 6.666 | 6.666 | |||||
| 2015-06-03 | 2015-06-02 | 4 | Freund John Gordon | PRTO | Stock Option (Right to Buy) | D | 17,59 | 6.666 | 6.666 | |||||
| 2015-06-03 | 2015-06-02 | 4 | PHELPS GREGORY D | PRTO | Stock Option (Right to Buy) | D | 17,59 | 6.666 | 6.666 | |||||
| 2015-06-03 | 2015-06-02 | 4 | Abingworth LLP By affiliate | PRTO | Stock Option (Right to Buy) | I | 17,59 | 6.666 | 6.666 | |||||
| 2015-06-03 | 2015-06-02 | 4 | Birner Hubert | PRTO | Stock Option (Right to Buy) | D | 17,59 | 6.666 | 6.666 | |||||
| 2015-06-03 | 2015-06-02 | 4 | O'Leary Brendan | PRTO | Stock Option (Right to Buy) | D | 17,59 | 6.666 | 6.666 | |||||
| 2015-06-03 | 2015-06-02 | 4 | Haines Timothy | PRTO | Stock Option (Right to Buy) | D | 17,59 | 6.666 | 6.666 | |||||
| 2015-06-03 | 2015-06-02 | 4 | Kobyzev Dmitry | PRTO | Stock Option (Right to Buy) | D | 17,59 | 6.666 | 6.666 | |||||
| 2015-06-03 | 2015-06-02 | 4 | Toner E. Scott | PRTO | Stock Option (Right to Buy) | D | 17,59 | 50.000 | 50.000 | |||||
| 2015-01-08 | 2015-01-07 | 4 | Gottlieb Daniel Philip | PRTO | Stock Option (Right to Buy) | D | 10,61 | 26.699 | 26.699 | |||||
| 2015-01-08 | 2015-01-07 | 4 | Eldridge, George Arthur | PRTO | Stock Option (Right to Buy) | D | 10,61 | 53.808 | 53.808 | |||||
| 2015-01-08 | 2015-01-07 | 4 | NOYES TIMOTHY P | PRTO | Stock Option (Right to Buy) | D | 10,61 | 134.333 | 134.333 | |||||
| 2015-01-08 | 2015-01-07 | 4 | Burke Steven Keith | PRTO | Stock Option (Right to Buy) | D | 10,61 | 69.813 | 69.813 | |||||
| 2014-10-30 | 2014-10-27 | 4 | Birner Hubert By TVM Life Science Ventures VI, L.P. | PRTO | Option (Right to Purchase) | I | -451.276 | 0 | ||||||
| 2014-10-30 | 2014-10-27 | 4 | Birner Hubert By TVM Life Science Ventures VI GmbH & Co. KG | PRTO | Option (Right to Purchase) | I | -1.316.683 | 0 | ||||||
| 2014-10-30 | 2014-10-27 | 4 | Birner Hubert By TVM Life Science Ventures VI, L.P. | PRTO | Warrants (Right to Buy) | I | 4,60 | -39.932 | 0 | |||||
| 2014-10-30 | 2014-10-27 | 4 | Birner Hubert By TVM Life Science Ventures VI GmbH & Co. KG | PRTO | Warrants (Right to Buy) | I | 4,60 | -116.511 | 0 | |||||
| 2014-10-30 | 2014-10-27 | 4 | Birner Hubert By TVM Life Science Ventures VI, L.P. | PRTO | Series D Convertible Preferred Stock | I | -1.277.663 | 0 | ||||||
| 2014-10-30 | 2014-10-27 | 4 | Birner Hubert By TVM Life Science Ventures VI GmbH & Co. KG | PRTO | Series D Convertible Preferred Stock | I | -3.727.823 | 0 | ||||||
| 2014-10-30 | 2014-10-27 | 4 | Birner Hubert By TVM Life Science Ventures VI, L.P. | PRTO | Series C Convertible Preferred Stock | I | -799.043 | 0 | ||||||
| 2014-10-30 | 2014-10-27 | 4 | Birner Hubert By TVM Life Science Ventures VI GmbH & Co. KG | PRTO | Series C Convertible Preferred Stock | I | -2.331.391 | 0 | ||||||
| 2014-10-30 | 2014-10-27 | 4 | Birner Hubert By TVM Life Science Ventures VI, L.P. | PRTO | Series B Convertible Preferred Stock | I | -835.121 | 0 | ||||||
| 2014-10-30 | 2014-10-27 | 4 | Birner Hubert By TVM Life Science Ventures VI GmbH & Co. KG | PRTO | Series B Convertible Preferred Stock | I | -2.436.618 | 0 | ||||||
| 2014-10-30 | 2014-10-27 | 4 | Birner Hubert By TVM Life Science Ventures VI, L.P. | PRTO | Series A-1 Convertible Preferred Stock | I | -717.260 | 0 | ||||||
| 2014-10-30 | 2014-10-27 | 4 | Birner Hubert By TVM Life Science Ventures VI GmbH & Co. KG | PRTO | Series A-1 Convertible Preferred Stock | I | -2.092.735 | 0 | ||||||
| 2014-10-30 | 2014-10-27 | 4 | Birner Hubert By TVM Life Science Ventures VI, L.P. | PRTO | Series A Convertible Preferred Stock | I | -1.531.518 | 0 | ||||||
| 2014-10-30 | 2014-10-27 | 4 | Birner Hubert By TVM Life Science Ventures VI GmbH & Co. KG | PRTO | Series A Convertible Preferred Stock | I | -4.468.482 | 0 | ||||||
| 2014-10-30 | 2014-10-27 | 4 | Birner Hubert By TVM Life Science Ventures VI, L.P.(3) | PRTO | Common Stock | I | 4,6023 | 39.932 | 184 | 1.943.059 | ||||
| 2014-10-30 | 2014-10-27 | 4 | Birner Hubert By TVM Life Science Ventures VI GmbH & Co. KG | PRTO | Common Stock | I | 4,6023 | 116.511 | 536 | 1.903.127 | ||||
| 2014-10-30 | 2014-10-27 | 4 | Birner Hubert By TVM Life Science Ventures VI, L.P. | PRTO | Common Stock | I | 379.462 | 1.786.616 | ||||||
| 2014-10-30 | 2014-10-27 | 4 | Birner Hubert By TVM Life Science Ventures VI GmbH & Co. KG | PRTO | Common Stock | I | 1.107.154 | 1.407.154 | ||||||
| 2014-10-30 | 2014-10-27 | 4 | Birner Hubert By TVM Life Science Ventures VI, L.P. | PRTO | Common Stock | I | 10,0000 | 76.590 | 766 | 300.000 | ||||
| 2014-10-30 | 2014-10-27 | 4 | Birner Hubert By TVM Life Science Ventures VI GmbH & Co. KG | PRTO | Common Stock | I | 10,0000 | 223.410 | 2.234 | 223.410 | ||||
| 2014-10-30 | 2014-10-27 | 4 | TVM Life Science Ventures VI GmbH & Co KG By TVM Life Science Ventures VI, L.P. | PRTO | Option (Right to Purchase) | I | -451.276 | 0 | ||||||
| 2014-10-30 | 2014-10-27 | 4 | TVM Life Science Ventures VI GmbH & Co KG | PRTO | Option (Right to Purchase) | D | -1.316.683 | 0 | ||||||
| 2014-10-30 | 2014-10-27 | 4 | TVM Life Science Ventures VI GmbH & Co KG By TVM Life Science Ventures VI, L.P. | PRTO | Warrants (Right to Buy) | I | 4,60 | -39.932 | 0 | |||||
| 2014-10-30 | 2014-10-27 | 4 | TVM Life Science Ventures VI GmbH & Co KG | PRTO | Warrants (Right to Buy) | D | 4,60 | -116.511 | 0 | |||||
| 2014-10-30 | 2014-10-27 | 4 | TVM Life Science Ventures VI GmbH & Co KG By TVM Life Science Ventures VI, L.P. | PRTO | Series D Convertible Preferred Stock | I | -1.277.663 | 0 | ||||||
| 2014-10-30 | 2014-10-27 | 4 | TVM Life Science Ventures VI GmbH & Co KG | PRTO | Series D Convertible Preferred Stock | D | -3.727.823 | 0 | ||||||
| 2014-10-30 | 2014-10-27 | 4 | TVM Life Science Ventures VI GmbH & Co KG By TVM Life Science Ventures VI, L.P. | PRTO | Series C Convertible Preferred Stock | I | -799.043 | 0 | ||||||
| 2014-10-30 | 2014-10-27 | 4 | TVM Life Science Ventures VI GmbH & Co KG | PRTO | Series C Convertible Preferred Stock | D | -2.331.391 | 0 | ||||||
| 2014-10-30 | 2014-10-27 | 4 | TVM Life Science Ventures VI GmbH & Co KG By TVM Life Science Ventures VI, L.P. | PRTO | Series B Convertible Preferred Stock | I | -835.121 | 0 | ||||||
| 2014-10-30 | 2014-10-27 | 4 | TVM Life Science Ventures VI GmbH & Co KG | PRTO | Series B Convertible Preferred Stock | D | -2.436.618 | 0 | ||||||
| 2014-10-30 | 2014-10-27 | 4 | TVM Life Science Ventures VI GmbH & Co KG By TVM Life Science Ventures VI, L.P. | PRTO | Series A-1 Convertible Preferred Stock | I | -717.260 | 0 | ||||||
| 2014-10-30 | 2014-10-27 | 4 | TVM Life Science Ventures VI GmbH & Co KG | PRTO | Series A-1 Convertible Preferred Stock | D | -2.092.735 | 0 | ||||||
| 2014-10-30 | 2014-10-27 | 4 | TVM Life Science Ventures VI GmbH & Co KG By TVM Life Science Ventures VI, L.P. | PRTO | Series A Convertible Preferred Stock | I | -1.531.518 | 0 | ||||||
| 2014-10-30 | 2014-10-27 | 4 | TVM Life Science Ventures VI GmbH & Co KG | PRTO | Series A Convertible Preferred Stock | D | -4.468.482 | 0 | ||||||
| 2014-10-30 | 2014-10-27 | 4 | TVM Life Science Ventures VI GmbH & Co KG By TVM Life Science Ventures VI, L.P. | PRTO | Common Stock | I | 4,6023 | 39.932 | 184 | 1.943.059 | ||||
| 2014-10-30 | 2014-10-27 | 4 | TVM Life Science Ventures VI GmbH & Co KG | PRTO | Common Stock | D | 4,6023 | 116.511 | 536 | 1.903.127 | ||||
| 2014-10-30 | 2014-10-27 | 4 | TVM Life Science Ventures VI GmbH & Co KG By TVM Life Science Ventures VI, L.P. | PRTO | Common Stock | I | 379.462 | 1.786.616 | ||||||
| 2014-10-30 | 2014-10-27 | 4 | TVM Life Science Ventures VI GmbH & Co KG | PRTO | Common Stock | D | 1.107.154 | 1.407.154 | ||||||
| 2014-10-30 | 2014-10-27 | 4 | TVM Life Science Ventures VI GmbH & Co KG By TVM Life Science Ventures VI, L.P. | PRTO | Common Stock | I | 10,0000 | 76.590 | 766 | 300.000 | ||||
| 2014-10-30 | 2014-10-27 | 4 | TVM Life Science Ventures VI GmbH & Co KG | PRTO | Common Stock | D | 10,0000 | 223.410 | 2.234 | 223.410 | ||||
| 2014-10-29 | 3/A | Burke Steven Keith | PRTO | Common Stock | D | 30.411 | ||||||||
| 2014-10-29 | 2014-10-27 | 4 | Freund John Gordon By Skyline Venture Partners Qualified Purchaser Fund IV, L.P. | PRTO | Option (Right to Purchase) | I | -1.389.064 | 0 | ||||||
| 2014-10-29 | 2014-10-27 | 4 | Freund John Gordon By Skyline Venture Partners Qualified Purchaser Fund IV, L.P. | PRTO | Warrants (Right to Buy) | I | 4,60 | -121.760 | 0 | |||||
| 2014-10-29 | 2014-10-27 | 4 | Freund John Gordon By Skyline Venture Partners Qualified Purchaser Fund IV, L.P. | PRTO | Series D Convertible Preferred Stock | I | -3.932.747 | 0 | ||||||
| 2014-10-29 | 2014-10-27 | 4 | Freund John Gordon By Skyline Venture Partners Qualified Purchaser Fund IV, L.P. | PRTO | Series C Convertible Preferred Stock | I | -2.436.437 | 0 | ||||||
| 2014-10-29 | 2014-10-27 | 4 | Freund John Gordon By Skyline Venture Partners Qualified Purchaser Fund IV, L.P. | PRTO | Series B Convertible Preferred Stock | I | -2.173.913 | 0 | ||||||
| 2014-10-29 | 2014-10-27 | 4 | Freund John Gordon By Skyline Venture Partners Qualified Purchaser Fund IV, L.P. | PRTO | Series A-1 Convertible Preferred Stock | I | -2.341.664 | 0 | ||||||
| 2014-10-29 | 2014-10-27 | 4 | Freund John Gordon By Skyline Venture Partners Qualified Purchaser Fund IV, L.P. | PRTO | Series A Convertible Preferred Stock | I | -5.000.000 | 0 | ||||||
| 2014-10-29 | 2014-10-27 | 4 | Freund John Gordon By Skyline Venture Partners Qualified Purchaser Fund IV, L.P. | PRTO | Common Stock | I | 10,0000 | -56.038 | -560 | 1.432.930 | ||||
| 2014-10-29 | 2014-10-27 | 4 | Freund John Gordon By Skyline Venture Partners Qualified Purchaser Fund IV, L.P. | PRTO | Common Stock | I | 4,6023 | 121.760 | 560 | 1.488.968 | ||||
| 2014-10-29 | 2014-10-27 | 4 | Freund John Gordon By Skyline Venture Partners Qualified Purchaser Fund IV, L.P. | PRTO | Common Stock | I | 1.167.208 | 1.367.208 | ||||||
| 2014-10-29 | 2014-10-27 | 4 | Freund John Gordon By Skyline Venture Partners Qualified Purchaser Fund IV, L.P. | PRTO | Common Stock | I | 10,0000 | 200.000 | 2.000 | 200.000 | ||||
| 2014-10-29 | 2014-10-27 | 4 | Skyline Venture Partners Qualified Purchaser Fund IV L P | PRTO | Option (Right to Purchase) | D | -1.389.064 | 0 | ||||||
| 2014-10-29 | 2014-10-27 | 4 | Skyline Venture Partners Qualified Purchaser Fund IV L P | PRTO | Warrants (Right to Buy) | D | 4,60 | -121.760 | 0 | |||||
| 2014-10-29 | 2014-10-27 | 4 | Skyline Venture Partners Qualified Purchaser Fund IV L P | PRTO | Series D Convertible Preferred Stock | D | -3.932.747 | 0 | ||||||
| 2014-10-29 | 2014-10-27 | 4 | Skyline Venture Partners Qualified Purchaser Fund IV L P | PRTO | Series C Convertible Preferred Stock | D | -2.436.437 | 0 | ||||||
| 2014-10-29 | 2014-10-27 | 4 | Skyline Venture Partners Qualified Purchaser Fund IV L P | PRTO | Series B Convertible Preferred Stock | D | -2.173.913 | 0 | ||||||
| 2014-10-29 | 2014-10-27 | 4 | Skyline Venture Partners Qualified Purchaser Fund IV L P | PRTO | Series A-1 Convertible Preferred Stock | D | -2.341.664 | 0 | ||||||
| 2014-10-29 | 2014-10-27 | 4 | Skyline Venture Partners Qualified Purchaser Fund IV L P | PRTO | Series A Convertible Preferred Stock | D | -5.000.000 | 0 | ||||||
| 2014-10-29 | 2014-10-27 | 4 | Skyline Venture Partners Qualified Purchaser Fund IV L P | PRTO | Common Stock | D | 10,0000 | -56.038 | -560 | 1.432.930 | ||||
| 2014-10-29 | 2014-10-27 | 4 | Skyline Venture Partners Qualified Purchaser Fund IV L P | PRTO | Common Stock | D | 4,6023 | 121.760 | 560 | 1.488.968 | ||||
| 2014-10-29 | 2014-10-27 | 4 | Skyline Venture Partners Qualified Purchaser Fund IV L P | PRTO | Common Stock | D | 1.167.208 | 1.367.208 | ||||||
| 2014-10-29 | 2014-10-27 | 4 | Skyline Venture Partners Qualified Purchaser Fund IV L P | PRTO | Common Stock | D | 10,0000 | 200.000 | 2.000 | 200.000 | ||||
| 2014-10-29 | 2014-10-27 | 4 | Abingworth LLP See Note | PRTO | Option (Right to Purchase) | I | -12.835.264 | 0 | ||||||
| 2014-10-29 | 2014-10-27 | 4 | Abingworth LLP See Note | PRTO | Series D Convertible Preferred Stock | I | -16.044.081 | 0 | ||||||
| 2014-10-29 | 2014-10-27 | 4 | Abingworth LLP See Note | PRTO | Common Stock | I | 1.067.872 | 2.017.872 | ||||||
| 2014-10-29 | 2014-10-27 | 4 | Abingworth LLP See Note | PRTO | Common Stock | I | 10,0000 | 950.000 | 9.500 | 950.000 | ||||
| 2014-10-29 | 2014-10-27 | 4 | O'Leary Brendan | PRTO | Common Stock Warrants | I | -1.965.454 | 0 | ||||||
| 2014-10-29 | 2014-10-27 | 4 | O'Leary Brendan | PRTO | Series D Convertible Preferred Stock | I | -4.000.070 | 0 | ||||||
| 2014-10-29 | 2014-10-27 | 4 | O'Leary Brendan | PRTO | Series C Convertible Preferred Stock | I | -2.478.183 | 0 | ||||||
| 2014-10-29 | 2014-10-27 | 4 | O'Leary Brendan | PRTO | Series B Convertible Preferred Stock | I | -2.336.956 | 0 | ||||||
| 2014-10-29 | 2014-10-27 | 4 | O'Leary Brendan | PRTO | Series A-1 Convertible Preferred Stock | I | -2.341.664 | 0 | ||||||
| 2014-10-29 | 2014-10-27 | 4 | O'Leary Brendan | PRTO | Series A Convertible Preferred Stock | I | -5.000.000 | 0 | ||||||
| 2014-10-29 | 2014-10-27 | 4 | O'Leary Brendan | PRTO | Common Stock | I | 10,0000 | 83.170 | 832 | 1.387.198 | ||||
| 2014-10-29 | 2014-10-27 | 4 | O'Leary Brendan | PRTO | Common Stock | I | 123.846 | 1.304.028 | ||||||
| 2014-10-29 | 2014-10-27 | 4 | O'Leary Brendan | PRTO | Common Stock | I | 252.052 | 1.180.182 | ||||||
| 2014-10-29 | 2014-10-27 | 4 | O'Leary Brendan | PRTO | Common Stock | I | 192.070 | 928.130 | ||||||
| 2014-10-29 | 2014-10-27 | 4 | O'Leary Brendan | PRTO | Common Stock | I | 181.125 | 736.060 | ||||||
| 2014-10-29 | 2014-10-27 | 4 | O'Leary Brendan | PRTO | Common Stock | I | 180.014 | 554.935 | ||||||
| 2014-10-29 | 2014-10-27 | 4 | O'Leary Brendan | PRTO | Common Stock | I | 374.921 | 374.921 | ||||||
| 2014-10-29 | 2014-10-27 | 4 | Haines Timothy By Abingworth Bioventures VI, LP | PRTO | Option (Right to Purchase) | I | -12.835.264 | 0 | ||||||
| 2014-10-29 | 2014-10-27 | 4 | Haines Timothy By Abingworth Bioventures VI, LP | PRTO | Series D Convertible Preferred Stock | I | -16.044.081 | 0 | ||||||
| 2014-10-29 | 2014-10-27 | 4 | Haines Timothy By Abingworth Bioventures VI, LP | PRTO | Common Stock | I | 1.067.872 | 2.017.872 | ||||||
| 2014-10-29 | 2014-10-27 | 4 | Haines Timothy By Abingworth Bioventures VI, LP | PRTO | Common Stock | I | 10,0000 | 950.000 | 9.500 | 950.000 | ||||
| 2014-10-29 | 2014-10-27 | 4 | Pharmstandard International S.A. | PRTO | Option (Right to Purchase) | D | -6.795.140 | 0 | ||||||
| 2014-10-29 | 2014-10-27 | 4 | Pharmstandard International S.A. | PRTO | Series D Convertible Preferred Stock | D | -8.493.925 | 0 | ||||||
| 2014-10-29 | 2014-10-27 | 4 | Pharmstandard International S.A. | PRTO | Common Stock | D | 565.344 | 1.165.344 | ||||||
| 2014-10-29 | 2014-10-27 | 4 | Pharmstandard International S.A. | PRTO | Common Stock | D | 10,0000 | 600.000 | 6.000 | 600.000 | ||||
| 2014-10-29 | 2014-10-27 | 4 | Kobyzev Dmitry By Pharmstandard International S.A | PRTO | Option (Right to Purchase) | I | -6.795.140 | 0 | ||||||
| 2014-10-29 | 2014-10-27 | 4 | Kobyzev Dmitry By Pharmstandard International S.A | PRTO | Series D Convertible Preferred Stock | I | -8.493.925 | 0 | ||||||
| 2014-10-29 | 2014-10-27 | 4 | Kobyzev Dmitry By Pharmstandard International S.A | PRTO | Common Stock | I | 565.344 | 1.165.344 | ||||||
| 2014-10-29 | 2014-10-27 | 4 | Kobyzev Dmitry By Pharmstandard International S.A | PRTO | Common Stock | I | 10,0000 | 600.000 | 6.000 | 600.000 | ||||
| 2014-10-27 | 2014-10-27 | 4 | Flynn James E Through Deerfield Special Situations International Master Fund, L.P. | PRTO | Series D Purchase Right | I | -838.067 | 0 | ||||||
| 2014-10-27 | 2014-10-27 | 4 | Flynn James E Through Deerfield Special Situations Fund, L.P. | PRTO | Series D Purchase Right | I | -1.049.472 | 0 | ||||||
| 2014-10-27 | 2014-10-27 | 4 | Flynn James E Through Deerfield Private Design Fund III, L.P. | PRTO | Series D Purchase Right | I | -4.907.601 | 0 | ||||||
| 2014-10-27 | 2014-10-27 | 4 | Flynn James E Through Deerfield Special Situations International Master Fund, L.P. | PRTO | Series D Preferred Stock | I | -1.047.584 | 0 | ||||||
| 2014-10-27 | 2014-10-27 | 4 | Flynn James E Through Deerfield Special Situations Fund, L.P. | PRTO | Series D Preferred Stock | I | -1.311.840 | 0 | ||||||
| 2014-10-27 | 2014-10-27 | 4 | Flynn James E Through Deerfield Private Design Fund III, L.P. | PRTO | Series D Preferred Stock | I | -6.134.501 | 0 | ||||||
| 2014-10-27 | 2014-10-27 | 4 | Flynn James E Through Deerfield Special Situations International Master Fund, L.P. | PRTO | Common Stock | I | 10,0000 | 45 | 0 | 170.371 | ||||
| 2014-10-27 | 2014-10-27 | 4 | Flynn James E Through Deerfield Special Situations Fund, L.P. | PRTO | Common Stock | I | 10,0000 | 55 | 1 | 208.345 | ||||
| 2014-10-27 | 2014-10-27 | 4 | Flynn James E Through Deerfield Special Situations International Master Fund, L.P. | PRTO | Common Stock | I | 10,0000 | 272 | 3 | 170.326 | ||||
| 2014-10-27 | 2014-10-27 | 4 | Flynn James E Through Deerfield Special Situations Fund, L.P. | PRTO | Common Stock | I | 10,0000 | 328 | 3 | 208.290 | ||||
| 2014-10-27 | 2014-10-27 | 4 | Flynn James E Through Deerfield Special Situations International Master Fund, L.P. | PRTO | Common Stock | I | 10,0000 | 12.819 | 128 | 170.054 | ||||
| 2014-10-27 | 2014-10-27 | 4 | Flynn James E Through Deerfield Special Situations Fund, L.P. | PRTO | Common Stock | I | 10,0000 | 15.417 | 154 | 207.962 | ||||
| 2014-10-27 | 2014-10-27 | 4 | Flynn James E Through Deerfield Special Situations International Master Fund, L.P. | PRTO | Common Stock | I | 10,0000 | 5.801 | 58 | 157.235 | ||||
| 2014-10-27 | 2014-10-27 | 4 | Flynn James E Through Deerfield Special Situations Fund, L.P. | PRTO | Common Stock | I | 10,0000 | 6.976 | 70 | 192.545 | ||||
| 2014-10-27 | 2014-10-27 | 4 | Flynn James E Through Deerfield Special Situations International Master Fund, L.P. | PRTO | Common Stock | I | 10,0000 | 81.949 | 819 | 151.434 | ||||
| 2014-10-27 | 2014-10-27 | 4 | Flynn James E Through Deerfield Special Situations Fund, L.P. | PRTO | Common Stock | I | 10,0000 | 98.556 | 986 | 185.569 | ||||
| 2014-10-27 | 2014-10-27 | 4 | Flynn James E Through Deerfield Private Design Fund III, L.P. | PRTO | Common Stock | I | 10,0000 | 469.495 | 4.695 | 876.391 | ||||
| 2014-10-27 | 2014-10-27 | 4 | Flynn James E Through Deerfield Special Situations International Master Fund, L.P. | PRTO | Common Stock | I | 69.485 | 69.485 | ||||||
| 2014-10-27 | 2014-10-27 | 4 | Flynn James E Through Deerfield Special Situations Fund, L.P. | PRTO | Common Stock | I | 87.013 | 87.013 | ||||||
| 2014-10-27 | 2014-10-27 | 4 | Flynn James E Through Deerfield Private Design Fund III, L.P. | PRTO | Common Stock | I | 406.896 | 406.896 |
P
Offener Markt oder privater Kauf von nicht-derivativen oder derivativen Wertpapieren
S
Freiverkauf oder privater Verkauf von nicht-derivativen oder derivativen Wertpapieren
A
Gewährung, Vergabe oder sonstiger Erwerb von Wertpapieren des Unternehmens (z. B. eine Option)
C
Umwandlung von Derivaten
D
Verkauf oder Rückübertragung von Wertpapieren an das Unternehmen
F
Zahlung des Ausübungspreises oder der Steuerschuld mit einem Teil der vom Unternehmen erhaltenen Wertpapiere
G
Schenkung von Wertpapieren durch oder an den Insider
K
Aktien-Swaps und ähnliche Absicherungstransaktionen
M
Ausübung oder Umwandlung eines vom Unternehmen erhaltenen derivativen Wertpapiers (z. B. einer Option)
V
Eine freiwillig auf Formular 4 gemeldete Transaktion
J
Sonstige (mit einer Fußnote zur Beschreibung der Transaktion)
