| Insider-Aktien | 6.872.638 shares |
Insider-Stimmungswert
Der Insider-Stimmungswert ermittelt die Unternehmen, die von Unternehmensinsidern gekauft werden.
Es ist das Ergebnis eines ausgeklügelten quantitativen Multifaktormodells, das die Unternehmen mit der höchsten Insiderakkumulation identifiziert. Das Scoring-Modell verwendet eine Kombination aus der Nettozahl der Insiderkäufe der letzten 90 Tage, der Gesamtzahl der gekauften Aktien als Prozentsatz des Streubesitzes und der Gesamtzahl der von Insidern gehaltenen Aktien. Die Zahl reicht von 0 bis 100, wobei höhere Zahlen ein höheres Maß an Insiderkäufen anzeigen als bei anderen Unternehmen und 50 den Durchschnitt darstellt.
Aktualisierungshäufigkeit: Täglich
Führungskräfte-Stimmungswert
Der Führungskräfte-Stimmungswert findet Unternehmen, die von Führungskräften des Unternehmens gekauft werden.
Per Definition sind Führungskräfte des Unternehmens Insider, aber im Gegensatz zu anderen Insidern (10%ige Aktionäre und Vorstandsmitglieder) arbeiten Führungskräfte täglich für das Unternehmen und verwenden beim Handel ihr eigenes Geld. (10%ige Aktionäre und Vorstandsmitglieder sind oft Fondsmanager, die das Geld anderer Leute verwalten.) Daher sind Insider-Geschäfte, die von Führungskräften getätigt werden, viel bedeutender und sollten entsprechend behandelt werden.
Wie der Insider-Stimmungswert ist auch der Führungskräfte-Stimmungswert das Ergebnis eines ausgeklügelten quantitativen Multifaktormodells, das die Unternehmen mit der höchsten Führungskräftekonzentration identifiziert.
Aktualisierungshäufigkeit: Täglich
Wichtige Insider-Kennzahlen
Diese Karte zeigt, wie das Unternehmen bei verschiedenen Insider-Kennzahlen abschneidet. Der Perzentil-Rang zeigt, wie dieses Unternehmen im Vergleich zu anderen Unternehmen auf den US-Märkten abschneidet. Höhere Ränge deuten auf eine bessere Situation hin.
Es ist beispielsweise allgemein anerkannt, dass Insiderkäufe ein positiver Indikator sind, so dass Unternehmen mit mehr Insiderkäufen besser abschneiden würden als Unternehmen mit weniger Insiderkäufen (oder sogar Insiderverkäufen).
Nettoanzahl der Insider, die kaufen (Rang)
N/A
Die Nettoanzahl der Insiderkäufe ist die Gesamtzahl der Insiderkäufe abzüglich der Gesamtzahl der Insiderverkäufe in den letzten 90 Tagen. Der Perzentilrang wird hier angezeigt (Bereich von 0 bis 100%).
Prozent des Streubesitzes von Insidern gekauft (Rang)
N/A
Prozent des von Insidern gekauften Streubesitzes ist die Gesamtzahl der von Insidern gekauften Aktien abzüglich der Gesamtzahl der von Insidern in den letzten 90 Tagen verkauften Aktien, geteilt durch den gesamten Streubesitz und multipliziert mit 100.
Diagramm zum Insiderhandel
Regulus Therapeutics Inc. Insider-Trades sind in der folgenden Grafik dargestellt. Insider sind leitende Angestellte, Direktoren oder bedeutende Investoren in einem Unternehmen. Im Allgemeinen ist es für Insider illegal, auf der Grundlage von wesentlichen, nicht-öffentlichen Informationen mit Aktien ihrer Unternehmen zu handeln. Das bedeutet nicht, dass es für sie illegal ist, irgendwelche Geschäfte in ihren eigenen Unternehmen zu tätigen. Sie müssen jedoch alle Geschäfte der SEC über ein Formular 4 melden.
Kennzahlen zu Insiderlisten und Rentabilität
Diese Tabelle zeigt die Liste der bekannten Insider und wird automatisch aus den bei der SEC eingereichten Unterlagen erstellt. Zusätzlich zu den Namen, dem letzten Titel und der Bezeichnung als Direktor, leitender Angestellter oder 10%-iger Anteilseigner geben wir die zuletzt veröffentlichten Bestände an. Zusätzlich stellen wir, wenn möglich, die historische Handelsperformance für den Insider zur Verfügung. Die historische Handelsperformance ist ein gewichteter Durchschnitt der Performance tatsächlicher offener Kauftransaktionen, die von dem Insider getätigt wurden. Weitere Informationen zur Berechnung dieses Wertes finden Sie in diesem YouTube-Webinar.
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| Insider | Durchschnittlicher Gewinn (%) | Aktien in Besitz |
Split Angepasst |
|---|
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Erfolgsbilanz der Insiderkäufe - Kurzfristige Gewinnanalyse
In diesem Abschnitt analysieren wir die Rentabilität jedes ungeplanten Insiderkaufs, der auf dem freien Markt in RGLS / Regulus Therapeutics Inc. getätigt wurde. Diese Analyse hilft zu verstehen, ob der Insider beständig abnormale Renditen erzielt und es sich lohnt, ihm zu folgen. Diese Analyse bezieht sich auf ein Jahr nach jedem Handel, und die Ergebnisse sind theoretisch .
Die folgende Tabelle zeigt die jüngsten Käufe am offenen Markt, die nicht Teil eines automatischen Handelsplans waren.
Bereinigter Preis ist der splitbereinigte Preis. Bereinigte Aktien sind die um den Split bereinigten Aktien.
Erfolgsbilanz von Insiderverkäufen - Kurzfristige Verlustanalyse
In diesem Abschnitt analysieren wir die kurzfristige Verlustvermeidung jedes ungeplanten Insider-Verkaufs auf dem freien Markt in RGLS / Regulus Therapeutics Inc.. Ein konsistentes Muster der Verlustvermeidung kann darauf hindeuten, dass zukünftige Verkaufstransaktionen Kursrückgänge vorhersagen können. Diese Analyse bezieht sich auf ein Jahr nach jedem Handel, und die Ergebnisse sind theoretisch .
Die folgende Tabelle zeigt die jüngsten Verkäufe am offenen Markt, die nicht Teil eines automatischen Handelsplans waren.
Bereinigter Preis ist der splitbereinigte Preis. Bereinigte Aktien sind die um den Split bereinigten Aktien.
Transaktionshistorie
Klicken Sie auf das Link-Symbol, um den vollständigen Transaktionsverlauf anzuzeigen. Transaktionen, die im Rahmen eines automatischen Handelsplans 10b5-1 gemeldet werden, sind in der Spalte 10b-5 mit einem X gekennzeichnet.
| Datei Datum |
Handel Datum |
Form | Insider | Ticker | Wertpapier-Titel | Code | Direkt | Ausführung Preis |
Einheit Preis |
Eimheiten Verändert |
Wert Geändert (1K) |
Verbleibende Optionen |
Verbleibende Aktien |
|
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2025-06-27 | 2025-06-25 | 4 | RASTETTER WILLIAM H By The Rastetter Family Trust | RGLS | Common Stock | I | -57.292 | 0 | ||||||
| 2025-06-27 | 2025-06-25 | 4 | RASTETTER WILLIAM H By The Rastetter Family Trust | RGLS | Common Stock | I | -44.264 | 57.292 | ||||||
| 2025-06-27 | 2025-06-25 | 4 | Witz Pascale | RGLS | Common Stock | D | -67.233 | 0 | ||||||
| 2025-06-27 | 2025-06-25 | 4 | PAPADOPOULOS STELIOS | RGLS | Common Stock | D | -64.635 | 0 | ||||||
| 2025-06-27 | 2025-06-25 | 4 | PAPADOPOULOS STELIOS | RGLS | Common Stock | D | -976.253 | 64.635 | ||||||
| 2025-06-27 | 2025-06-25 | 4 | Rosen Hugh | RGLS | Common Stock | D | -57.292 | 0 | ||||||
| 2025-06-27 | 2025-06-25 | 4 | Rosen Hugh | RGLS | Common Stock | D | -6.979 | 57.292 | ||||||
| 2025-06-27 | 2025-06-25 | 4 | Aker Christopher Ray | RGLS | Common Stock | D | -83.125 | 0 | ||||||
| 2025-06-27 | 2025-06-25 | 4 | Aker Christopher Ray | RGLS | Common Stock | D | -60.796 | 83.125 | ||||||
| 2025-06-27 | 2025-06-25 | 4 | Klassen Preston | RGLS | Common Stock | D | -115.555 | 0 | ||||||
| 2025-06-27 | 2025-06-25 | 4 | Hagan Joseph P | RGLS | Common Stock | D | -571.558 | 0 | ||||||
| 2025-06-27 | 2025-06-25 | 4 | BALTIMORE DAVID | RGLS | Common Stock | D | -57.292 | 0 | ||||||
| 2025-06-27 | 2025-06-25 | 4 | BALTIMORE DAVID By Spouse | RGLS | Common Stock | I | -57.292 | 0 | ||||||
| 2025-06-27 | 2025-06-25 | 4 | BALTIMORE DAVID By Spouse | RGLS | Common Stock | I | -5.208 | 57.292 | ||||||
| 2025-06-27 | 2025-06-25 | 4 | BALTIMORE DAVID | RGLS | Common Stock | D | -27.377 | 57.292 | ||||||
| 2025-06-27 | 2025-06-25 | 4 | Nunn Jason Raleigh | RGLS | Common Stock | D | -62.500 | 0 | ||||||
| 2025-06-27 | 2025-06-25 | 4 | Huang Alice Shih-hou | RGLS | Common Stock | D | -57.292 | 0 | ||||||
| 2025-06-27 | 2025-06-25 | 4 | Huang Alice Shih-hou By Spouse | RGLS | Common Stock | I | -57.292 | 0 | ||||||
| 2025-06-27 | 2025-06-25 | 4 | Huang Alice Shih-hou By Spouse | RGLS | Common Stock | I | -27.377 | 57.292 | ||||||
| 2025-06-27 | 2025-06-25 | 4 | Huang Alice Shih-hou | RGLS | Common Stock | D | -5.208 | 57.292 | ||||||
| 2025-06-27 | 2025-06-25 | 4 | Collier Kathryn J | RGLS | Common Stock | D | -75.565 | 0 | ||||||
| 2025-06-27 | 2025-06-25 | 4 | CALSADA CRISPINA | RGLS | Common Stock | D | -140.228 | 0 | ||||||
| 2025-06-18 | 2025-06-17 | 4 | Collier Kathryn J | RGLS | Common Stock | D | 8,8000 | 2.325 | 20 | 62.915 | ||||
| 2025-06-18 | 2025-06-17 | 4 | Collier Kathryn J | RGLS | Common Stock | D | 9,9000 | 2.604 | 26 | 65.240 | ||||
| 2025-06-18 | 2025-06-16 | 4 | Collier Kathryn J | RGLS | Common Stock | D | 9,9000 | 1.396 | 14 | 67.844 | ||||
| 2025-06-04 | 2025-06-03 | 4 | Klassen Preston | RGLS | Common Stock | D | 7,9877 | 12.000 | 96 | 48.055 | ||||
| 2025-04-30 | 2025-04-30 | 4 | Nunn Jason Raleigh | RGLS | Common Stock | D | 62.500 | 62.500 | ||||||
| 2025-04-30 | 2025-04-30 | 4 | Collier Kathryn J | RGLS | Common Stock | D | 62.500 | 69.240 | ||||||
| 2025-04-30 | 2025-04-30 | 4 | Witz Pascale | RGLS | Common Stock | D | 62.500 | 67.233 | ||||||
| 2025-04-30 | 2025-04-30 | 4 | Huang Alice Shih-hou | RGLS | Common Stock | D | 62.500 | 84.669 | ||||||
| 2025-04-30 | 2025-04-30 | 4 | Huang Alice Shih-hou By Spouse | RGLS | Common Stock | I | 62.500 | 84.669 | ||||||
| 2025-04-30 | 2025-04-30 | 4 | BALTIMORE DAVID | RGLS | Common Stock | D | 62.500 | 62.500 | ||||||
| 2025-04-30 | 2025-04-30 | 4 | BALTIMORE DAVID By Spouse | RGLS | Common Stock | I | 62.500 | 62.500 | ||||||
| 2025-04-30 | 2025-04-30 | 4 | PAPADOPOULOS STELIOS | RGLS | Common Stock | D | 62.500 | 1.040.888 | ||||||
| 2025-04-30 | 2025-04-30 | 4 | RASTETTER WILLIAM H The Rastetter Family Trust | RGLS | Common Stock | I | 62.500 | 101.556 | ||||||
| 2025-04-30 | 2025-04-30 | 4 | Rosen Hugh | RGLS | Common Stock | D | 62.500 | 64.271 | ||||||
| 2025-01-31 | 2025-01-30 | 4 | BALTIMORE DAVID | RGLS | Common Stock | D | 1,0600 | 19.610 | 21 | 22.169 | ||||
| 2025-01-31 | 2025-01-30 | 4 | Hagan Joseph P | RGLS | Common Stock | D | 1,0852 | 50.000 | 54 | 260.808 | ||||
| 2025-01-15 | 2025-01-13 | 4 | Klassen Preston | RGLS | Common Stock | D | 1,2632 | -31.445 | -40 | 36.055 | ||||
| 2025-01-15 | 2025-01-14 | 4 | CALSADA CRISPINA | RGLS | Common Stock | D | 1,2632 | -5.088 | -6 | 45.478 | ||||
| 2025-01-15 | 2025-01-13 | 4 | CALSADA CRISPINA | RGLS | Common Stock | D | 1,2632 | -38.716 | -49 | 50.566 | ||||
| 2025-01-15 | 2025-01-14 | 4 | Hagan Joseph P | RGLS | Common Stock | D | 1,2632 | -11.764 | -15 | 210.808 | ||||
| 2025-01-15 | 2025-01-13 | 4 | Hagan Joseph P | RGLS | Common Stock | D | 1,2632 | -115.290 | -146 | 222.572 | ||||
| 2025-01-15 | 2025-01-14 | 4 | Aker Christopher Ray | RGLS | Common Stock | D | 1,2632 | -5.088 | -6 | 49.546 | ||||
| 2025-01-15 | 2025-01-13 | 4 | Aker Christopher Ray | RGLS | Common Stock | D | 1,2632 | -38.547 | -49 | 54.634 | ||||
| 2025-01-10 | 2025-01-09 | 4 | CALSADA CRISPINA | RGLS | Common Stock | D | 1,3000 | 21.000 | 27 | 89.282 | ||||
| 2025-01-10 | 2025-01-09 | 4 | CALSADA CRISPINA | RGLS | Common Stock | D | 1,3600 | 62.500 | 85 | 68.282 | ||||
| 2025-01-10 | 2025-01-09 | 4 | Hagan Joseph P | RGLS | Common Stock | D | 1,3000 | 62.000 | 81 | 337.862 | ||||
| 2025-01-10 | 2025-01-09 | 4 | Hagan Joseph P | RGLS | Common Stock | D | 1,3600 | 218.750 | 298 | 275.862 | ||||
| 2025-01-10 | 2025-01-09 | 4 | Klassen Preston | RGLS | Common Stock | D | 1,3000 | 30.000 | 39 | 67.500 | ||||
| 2025-01-10 | 2025-01-09 | 4 | Klassen Preston | RGLS | Common Stock | D | 1,3600 | 37.500 | 51 | 37.500 | ||||
| 2025-01-10 | 2025-01-09 | 4 | Aker Christopher Ray | RGLS | Common Stock | D | 1,3000 | 17.500 | 23 | 93.181 | ||||
| 2025-01-10 | 2025-01-09 | 4 | Aker Christopher Ray | RGLS | Common Stock | D | 1,3600 | 66.625 | 91 | 75.681 | ||||
| 2024-07-29 | 2024-07-25 | 4 | Collier Kathryn J | RGLS | Common Stock | D | 1,8200 | 4.000 | 7 | 6.740 | ||||
| 2024-03-15 | 2024-03-14 | 4 | PAPADOPOULOS STELIOS | RGLS | Common Stock | D | 1,6000 | 250.000 | 400 | 978.388 | ||||
| 2024-01-18 | 2024-01-18 | 4 | CALSADA CRISPINA | RGLS | Common Stock | D | 1,1906 | -5.468 | -7 | 5.782 | ||||
| 2024-01-18 | 2024-01-18 | 4 | Aker Christopher Ray | RGLS | Common Stock | D | 1,1906 | -5.468 | -7 | 10.056 | ||||
| 2024-01-18 | 2024-01-18 | 4 | Hagan Joseph P | RGLS | Common Stock | D | 1,1906 | -14.580 | -17 | 57.112 | ||||
| 2024-01-17 | 2024-01-12 | 4 | Hagan Joseph P | RGLS | Common Stock | D | 30.000 | 71.692 | ||||||
| 2024-01-17 | 2024-01-12 | 4 | CALSADA CRISPINA | RGLS | Common Stock | D | 11.250 | 11.250 | ||||||
| 2024-01-17 | 2024-01-12 | 4 | Aker Christopher Ray | RGLS | Common Stock | D | 11.250 | 15.524 | ||||||
| 2023-04-14 | 2023-04-13 | 4 | PAPADOPOULOS STELIOS | RGLS | Common Stock | D | 0,9001 | 222.198 | 200 | 728.388 | ||||
| 2022-05-11 | 2022-05-10 | 4 | Hagan Joseph P | RGLS | Stock Option (Right to Buy) | D | 1,31 | 300.000 | 300.000 | |||||
| 2022-05-11 | 2022-05-10 | 4 | CALSADA CRISPINA | RGLS | Stock Option (Right to Buy) | D | 1,31 | 50.000 | 50.000 | |||||
| 2022-05-11 | 2022-05-09 | 4 | Aker Christopher Ray | RGLS | Stock Option (Right to Buy) | D | 1,31 | 70.000 | 70.000 | |||||
| 2022-03-01 | 2022-03-01 | 4 | Drygin Denis | RGLS | Common Stock | D | 0,2300 | 76.686 | 18 | 100.000 | ||||
| 2022-02-07 | 2022-02-04 | 4 | Drygin Denis | RGLS | Common Stock | D | 0,2300 | 23.314 | 5 | 23.314 | ||||
| 2022-01-26 | 2022-01-26 | 4 | Hagan Joseph P | RGLS | Common Stock | D | 0,2152 | 100.000 | 22 | 417.006 | ||||
| 2022-01-26 | 2022-01-12 | 4 | Hagan Joseph P | RGLS | Stock Option (Right to Buy) | D | 0,26 | 1.600.000 | 1.600.000 | |||||
| 2022-01-26 | 2022-01-12 | 4 | Drygin Denis | RGLS | Stock Option (Right to Buy) | D | 0,26 | 400.000 | 400.000 | |||||
| 2022-01-26 | 2022-01-12 | 4 | CALSADA CRISPINA | RGLS | Stock Option (Right to Buy) | D | 0,26 | 480.000 | 480.000 | |||||
| 2022-01-26 | 2022-01-12 | 4 | Aker Christopher Ray | RGLS | Stock Option (Right to Buy) | D | 0,26 | 480.000 | 480.000 | |||||
| 2021-12-01 | 2021-11-30 | 4 | PAPADOPOULOS STELIOS | RGLS | Common Stock | D | 0,3600 | 2.222.222 | 800 | 5.061.929 | ||||
| 2021-06-15 | 2021-06-14 | 4 | Simeonidis Simos | RGLS | Stock Option (Right to Buy) | D | 0,99 | 40.000 | 40.000 | |||||
| 2021-06-15 | 2021-06-14 | 4 | Witz Pascale | RGLS | Stock Option (Right to Buy) | D | 0,99 | 40.000 | 40.000 | |||||
| 2021-06-15 | 2021-06-14 | 4 | Rosen Hugh | RGLS | Stock Option (Right to Buy) | D | 0,99 | 40.000 | 40.000 | |||||
| 2021-06-15 | 2021-06-14 | 4 | RASTETTER WILLIAM H | RGLS | Stock Option (Right to Buy) | D | 0,99 | 40.000 | 40.000 | |||||
| 2021-06-15 | 2021-06-14 | 4 | Nunn Jason Raleigh | RGLS | Stock Option (Right to Buy) | D | 0,99 | 40.000 | 40.000 | |||||
| 2021-06-15 | 2021-06-14 | 4 | PAPADOPOULOS STELIOS | RGLS | Stock Option (Right to Buy) | D | 0,99 | 40.000 | 40.000 | |||||
| 2021-06-15 | 2021-06-14 | 4 | Huang Alice Shih-hou | RGLS | Stock Option (Right to Buy) | D | 0,99 | 40.000 | 40.000 | |||||
| 2021-06-15 | 2021-06-14 | 4 | Collier Kathryn J | RGLS | Stock Option (Right to Buy) | D | 0,99 | 40.000 | 40.000 | |||||
| 2021-06-15 | 2021-06-14 | 4 | BALTIMORE DAVID | RGLS | Stock Option (Right to Buy) | D | 0,99 | 40.000 | 40.000 | |||||
| 2021-05-17 | 2021-05-17 | 4 | Hagan Joseph P | RGLS | Common Stock | D | 0,8900 | -4.186 | -4 | 316.292 | ||||
| 2021-05-17 | 2021-05-17 | 4 | Aker Christopher Ray | RGLS | Common Stock | D | 0,8900 | -860 | -1 | 41.754 | ||||
| 2021-04-16 | 2021-04-14 | 4 | Hagan Joseph P PACIFIC PREMIER TRUST OBO JOSEPH P. HAGAN IRA | RGLS | Class A-2 Convertible Preferred Stock | I | 7.585 | 0 | ||||||
| 2021-04-16 | 2021-04-14 | 4 | Hagan Joseph P | RGLS | Common Stock | D | 75.850 | 320.478 | ||||||
| 2021-04-16 | 2021-02-16 | 4/A | Hagan Joseph P | RGLS | Common Stock | D | 1,7200 | -4.144 | -7 | 244.628 | ||||
| 2021-02-17 | 2021-02-16 | 4 | Hagan Joseph P | RGLS | Common Stock | D | 1,7200 | -4.144 | -7 | 485.756 | ||||
| 2021-02-17 | 2021-02-16 | 4 | Aker Christopher Ray | RGLS | Common Stock | D | 1,7200 | -828 | -1 | 42.614 | ||||
| 2021-02-05 | 2021-02-04 | 4 | Hagan Joseph P | RGLS | Stock Option (Right to Buy) | D | 1,59 | 600.000 | 600.000 | |||||
| 2021-02-05 | 2021-02-04 | 4 | Drygin Denis | RGLS | Stock Option (Right to Buy) | D | 1,59 | 120.000 | 120.000 | |||||
| 2021-02-05 | 2021-02-04 | 4 | Aker Christopher Ray | RGLS | Stock Option (Right to Buy) | D | 1,59 | 180.000 | 180.000 | |||||
| 2021-02-05 | 2021-02-04 | 4 | CALSADA CRISPINA | RGLS | Stock Option (Right to Buy) | D | 1,59 | 150.000 | 150.000 | |||||
| 2021-01-27 | 2021-01-26 | 4 | Huang Alice Shih-hou | RGLS | Stock Option (Right to Buy) | D | 1,55 | 80.000 | 80.000 | |||||
| 2021-01-27 | 3 | Huang Alice Shih-hou By Spouse | RGLS | Common Stock | I | 25.604 | ||||||||
| 2021-01-27 | 2020-12-04 | 4/A | PAPADOPOULOS STELIOS | RGLS | Common Stock | D | 0,6301 | 793.528 | 500 | 2.839.707 | ||||
| 2020-12-07 | 2020-12-04 | 4 | Sonsini Peter W. See Note 2 | RGLS | Class A-3 Convertible Preferred Stock | I | 6,2200 | 258.707 | 1.609 | 258.707 | ||||
| 2020-12-07 | 2020-12-04 | 4 | Sonsini Peter W. See Note 2 | RGLS | Common Stock Purchase Warrant (right to buy) | I | 0,75 | 0,1250 | 5.239.254 | 655 | 5.239.254 | |||
| 2020-12-07 | 2020-12-04 | 4 | Sonsini Peter W. See Note 2 | RGLS | Common Stock | I | 0,6220 | 4.398.602 | 2.736 | 6.451.056 | ||||
| 2020-12-07 | 2020-12-04 | 4 | Walker Paul Edward See Note 2 | RGLS | Class A-3 Convertible Preferred Stock | I | 6,2200 | 258.707 | 1.609 | 258.707 | ||||
| 2020-12-07 | 2020-12-04 | 4 | Walker Paul Edward See Note 2 | RGLS | Common Stock Purchase Warrant (right to buy) | I | 0,75 | 0,1250 | 5.239.254 | 655 | 5.239.254 | |||
| 2020-12-07 | 2020-12-04 | 4 | Walker Paul Edward See Note 2 | RGLS | Common Stock | I | 0,6220 | 4.398.602 | 2.736 | 6.451.056 | ||||
| 2020-12-07 | 2020-12-04 | 4 | BASKETT FOREST See Note 2 | RGLS | Class A-3 Convertible Preferred Stock | I | 6,2200 | 258.707 | 1.609 | 258.707 | ||||
| 2020-12-07 | 2020-12-04 | 4 | BASKETT FOREST See Note 2 | RGLS | Common Stock Purchase Warrant (right to buy) | I | 0,75 | 0,1250 | 5.239.254 | 655 | 5.239.254 | |||
| 2020-12-07 | 2020-12-04 | 4 | BASKETT FOREST See Note 2 | RGLS | Common Stock | I | 0,6220 | 4.398.602 | 2.736 | 6.451.056 | ||||
| 2020-12-07 | 2020-12-04 | 4 | Behbahani Ali See Note 2 | RGLS | Class A-3 Convertible Preferred Stock | I | 6,2200 | 258.707 | 1.609 | 258.707 | ||||
| 2020-12-07 | 2020-12-04 | 4 | Behbahani Ali See Note 2 | RGLS | Common Stock Purchase Warrant (right to buy) | I | 0,75 | 0,1250 | 5.239.254 | 655 | 5.239.254 | |||
| 2020-12-07 | 2020-12-04 | 4 | Behbahani Ali See Note 2 | RGLS | Common Stock | I | 0,6220 | 4.398.602 | 2.736 | 6.451.056 | ||||
| 2020-12-07 | 2020-12-04 | 4 | Chang Carmen See Note 2 | RGLS | Class A-3 Convertible Preferred Stock | I | 6,2200 | 258.707 | 1.609 | 258.707 | ||||
| 2020-12-07 | 2020-12-04 | 4 | Chang Carmen See Note 2 | RGLS | Common Stock Purchase Warrant (right to buy) | I | 0,75 | 0,1250 | 5.239.254 | 655 | 5.239.254 | |||
| 2020-12-07 | 2020-12-04 | 4 | Chang Carmen See Note 2 | RGLS | Common Stock | I | 0,6220 | 4.398.602 | 2.736 | 6.451.056 | ||||
| 2020-12-07 | 2020-12-04 | 4 | Florence Anthony A. Jr. See Note 2 | RGLS | Class A-3 Convertible Preferred Stock | I | 6,2200 | 258.707 | 1.609 | 258.707 | ||||
| 2020-12-07 | 2020-12-04 | 4 | Florence Anthony A. Jr. See Note 2 | RGLS | Common Stock Purchase Warrant (right to buy) | I | 0,75 | 0,1250 | 5.239.254 | 655 | 5.239.254 | |||
| 2020-12-07 | 2020-12-04 | 4 | Florence Anthony A. Jr. See Note 2 | RGLS | Common Stock | I | 0,6220 | 4.398.602 | 2.736 | 6.451.056 | ||||
| 2020-12-07 | 2020-12-04 | 4 | Makhzoumi Mohamad See Note 2 | RGLS | Class A-3 Convertible Preferred Stock | I | 6,2200 | 258.707 | 1.609 | 258.707 | ||||
| 2020-12-07 | 2020-12-04 | 4 | Makhzoumi Mohamad See Note 2 | RGLS | Common Stock Purchase Warrant (right to buy) | I | 0,75 | 0,1250 | 5.239.254 | 655 | 5.239.254 | |||
| 2020-12-07 | 2020-12-04 | 4 | Makhzoumi Mohamad See Note 2 | RGLS | Common Stock | I | 0,6220 | 4.398.602 | 2.736 | 6.451.056 | ||||
| 2020-12-07 | 2020-12-04 | 4 | MAKOWER JOSHUA See Note 2 | RGLS | Class A-3 Convertible Preferred Stock | I | 6,2200 | 258.707 | 1.609 | 258.707 | ||||
| 2020-12-07 | 2020-12-04 | 4 | MAKOWER JOSHUA See Note 2 | RGLS | Common Stock Purchase Warrant (right to buy) | I | 0,75 | 0,1250 | 5.239.254 | 655 | 5.239.254 | |||
| 2020-12-07 | 2020-12-04 | 4 | MAKOWER JOSHUA See Note 2 | RGLS | Common Stock | I | 0,6220 | 4.398.602 | 2.736 | 6.451.056 | ||||
| 2020-12-07 | 2020-12-04 | 4 | SANDELL SCOTT D See Note 2 | RGLS | Class A-3 Convertible Preferred Stock | I | 6,2200 | 258.707 | 1.609 | 258.707 | ||||
| 2020-12-07 | 2020-12-04 | 4 | SANDELL SCOTT D See Note 2 | RGLS | Common Stock Purchase Warrant (right to buy) | I | 0,75 | 0,1250 | 5.239.254 | 655 | 5.239.254 | |||
| 2020-12-07 | 2020-12-04 | 4 | SANDELL SCOTT D See Note 2 | RGLS | Common Stock | I | 0,6220 | 4.398.602 | 2.736 | 6.451.056 | ||||
| 2020-12-07 | 2020-12-04 | 4 | Growth Equity Opportunities V, LLC | RGLS | Class A-3 Convertible Preferred Stock | D | 6,2200 | 258.707 | 1.609 | 258.707 | ||||
| 2020-12-07 | 2020-12-04 | 4 | Growth Equity Opportunities V, LLC | RGLS | Common Stock Purchase Warrant (right to buy) | D | 0,75 | 0,1250 | 5.239.254 | 655 | 5.239.254 | |||
| 2020-12-07 | 2020-12-04 | 4 | Growth Equity Opportunities V, LLC | RGLS | Common Stock | D | 0,6220 | 4.398.602 | 2.736 | 6.451.056 | ||||
| 2020-12-07 | 2020-12-04 | 4 | PAPADOPOULOS STELIOS | RGLS | Common Stock Purchase Warrant (Right to Buy) | D | 0,75 | 0,1250 | 595.146 | 74 | 595.146 | |||
| 2020-12-07 | 2020-12-04 | 4 | PAPADOPOULOS STELIOS | RGLS | Common Stock | D | 0,6301 | 793.528 | 500 | 1.986.729 | ||||
| 2020-12-07 | 2020-12-04 | 4 | Hagan Joseph P Securities purchased through an affiliated investment entity | RGLS | Common Stock Purchase Warrant (Right to Buy) | I | 0,75 | 0,1250 | 29.760 | 4 | 29.760 | |||
| 2020-12-07 | 2020-12-04 | 4 | Hagan Joseph P Securities purchased through an affiliated investment entity | RGLS | Common Stock | I | 0,6301 | 39.680 | 25 | 225.674 | ||||
| 2020-11-18 | 2020-11-16 | 4 | Aker Christopher Ray | RGLS | Common Stock | D | 0,5211 | -876 | -0 | 25.762 | ||||
| 2020-11-18 | 2020-11-16 | 4 | Hagan Joseph P | RGLS | Common Stock | D | 0,5211 | -6.094 | -3 | 215.994 | ||||
| 2020-08-17 | 2020-08-14 | 4 | Hagan Joseph P | RGLS | Common Stock | D | 0,6049 | -4.245 | -3 | 222.088 | ||||
| 2020-08-17 | 2020-08-14 | 4 | Aker Christopher Ray | RGLS | Common Stock | D | 0,6050 | -872 | -1 | 26.638 | ||||
| 2020-08-05 | 2020-03-03 | 4 | Drygin Denis | RGLS | Stock Option (Right to Buy) | D | 0,69 | 300.000 | 300.000 | |||||
| 2020-06-19 | 2020-06-17 | 4 | BALTIMORE DAVID | RGLS | Stock Option (Right to Buy) | D | 0,88 | 23.250 | 23.250 | |||||
| 2020-06-19 | 2020-06-17 | 4 | Collier Kathryn J | RGLS | Stock Option (Right to Buy) | D | 0,88 | 23.250 | 23.250 | |||||
| 2020-06-19 | 2020-06-17 | 4 | Nunn Jason Raleigh | RGLS | Stock Option (Right to Buy) | D | 0,88 | 23.250 | 23.250 | |||||
| 2020-06-19 | 2020-06-17 | 4 | PAPADOPOULOS STELIOS | RGLS | Stock Option (Right to Buy) | D | 0,88 | 23.250 | 23.250 | |||||
| 2020-06-19 | 2020-06-17 | 4 | RASTETTER WILLIAM H THE RASTETTER FAMILY TRUST DTD 9-2-2010 | RGLS | Stock Option (Right to Buy) | I | 0,88 | 23.250 | 23.250 | |||||
| 2020-06-19 | 2020-06-17 | 4 | Rosen Hugh | RGLS | Stock Option (Right to Buy) | D | 0,88 | 23.250 | 23.250 | |||||
| 2020-06-19 | 2020-06-17 | 4 | Simeonidis Simos | RGLS | Stock Option (Right to Buy) | D | 0,88 | 23.250 | 23.250 | |||||
| 2020-06-19 | 2020-06-17 | 4 | Witz Pascale | RGLS | Stock Option (Right to Buy) | D | 0,88 | 23.250 | 23.250 | |||||
| 2020-05-18 | 2020-05-15 | 4 | Aker Christopher Ray | RGLS | Common Stock | D | 0,6268 | -909 | -1 | 27.510 | ||||
| 2020-05-18 | 2020-05-15 | 4 | Hagan Joseph P | RGLS | Common Stock | D | 0,6267 | -4.426 | -3 | 226.333 | ||||
| 2020-05-08 | 3 | Sarissa Capital Master Fund II LP | RGLS | Common Stock | D | 152.712 | ||||||||
| 2020-05-08 | 3 | Sarissa Capital Master Fund II LP | RGLS | Common Stock | D | 152.712 | ||||||||
| 2020-05-08 | 3 | Sarissa Capital Master Fund II LP | RGLS | Common Stock | D | 152.712 | ||||||||
| 2020-05-08 | 2020-04-01 | 4 | Sarissa Capital Offshore Master Fund LP | RGLS | Warrants to Purchase Common Stock | D | 0,67 | -53.113 | 2.627.037 | |||||
| 2020-05-08 | 2020-04-01 | 4 | Sarissa Capital Offshore Master Fund LP | RGLS | Warrants to Purchase Common Stock | D | 1,08 | -23.243 | 1.149.649 | |||||
| 2020-05-08 | 2020-04-01 | 4 | Sarissa Capital Offshore Master Fund LP | RGLS | Class A-2 Convertible Preferred Stock | D | -5.311 | 262.704 | ||||||
| 2020-02-19 | 2020-02-18 | 4 | Hagan Joseph P | RGLS | Common Stock | D | 0,8304 | -4.324 | -4 | 230.759 | ||||
| 2020-02-19 | 2020-02-18 | 4 | Aker Christopher Ray | RGLS | Common Stock | D | 0,8305 | -888 | -1 | 28.419 | ||||
| 2020-02-04 | 2020-02-03 | 4 | RASTETTER WILLIAM H The Rastetter Family Trust dtd 9-2-2010 | RGLS | Class A-2 Convertible Preferred Stock | I | -22.594 | 0 | ||||||
| 2020-02-04 | 2020-02-03 | 4 | RASTETTER WILLIAM H The Rastetter Family Trust dtd 9-2-2010 | RGLS | Common Stock | I | 225.940 | 390.584 | ||||||
| 2020-02-04 | 2020-02-03 | 4 | PAPADOPOULOS STELIOS | RGLS | Class A-2 Convertible Preferred Stock | D | -84.632 | 0 | ||||||
| 2020-02-04 | 2020-02-03 | 4 | PAPADOPOULOS STELIOS | RGLS | Common Stock | D | 846.320 | 2.039.521 | ||||||
| 2020-01-24 | 2020-01-22 | 4 | Aker Christopher Ray | RGLS | Stock Option (Right to Buy) | D | 1,31 | 210.000 | 210.000 | |||||
| 2020-01-24 | 2020-01-22 | 4 | CALSADA CRISPINA | RGLS | Stock Option (Right to Buy) | D | 1,31 | 150.000 | 150.000 | |||||
| 2020-01-24 | 2020-01-22 | 4 | Hagan Joseph P | RGLS | Stock Option (Right to Buy) | D | 1,31 | 900.000 | 900.000 | |||||
| 2020-01-03 | 2019-12-24 | 4 | DENNER ALEXANDER J See Footnotes | RGLS | Warrants to Purchase Common Stock | I | 6,66 | 4.231.620 | 6.083.471 | |||||
| 2020-01-03 | 2019-12-24 | 4 | DENNER ALEXANDER J See Footnotes | RGLS | Class A-2 Convertible Preferred Stock | I | 0,67 | 423.162 | 423.162 | |||||
| 2020-01-03 | 2020-01-02 | 4 | Aker Christopher Ray | RGLS | Common Stock | D | 0,9667 | -2.239 | -2 | 29.307 | ||||
| 2020-01-03 | 2020-01-02 | 4 | Hagan Joseph P | RGLS | Common Stock | D | 0,9667 | -8.345 | -8 | 235.083 | ||||
| 2019-12-26 | 2019-12-24 | 4 | SANDELL SCOTT D See Note 1 | RGLS | Class A-2 Convertible Preferred Stock | I | 6,6600 | 900.900 | 6.000 | 900.900 | ||||
| 2019-12-26 | 2019-12-24 | 4 | SANDELL SCOTT D See Note 1 | RGLS | Common Stock Purchase Warrant (Right to Buy) | I | 0,67 | 0,1250 | 9.009.000 | 1.126 | 9.009.000 | |||
| 2019-12-26 | 2019-12-24 | 4 | Sonsini Peter W. See Note 1 | RGLS | Class A-2 Convertible Preferred Stock | I | 6,6600 | 900.900 | 6.000 | 900.900 | ||||
| 2019-12-26 | 2019-12-24 | 4 | Sonsini Peter W. See Note 1 | RGLS | Common Stock Purchase Warrant (Right to Buy) | I | 0,67 | 0,1250 | 9.009.000 | 1.126 | 9.009.000 | |||
| 2019-12-26 | 2019-12-24 | 4 | Walker Paul Edward See Note 1 | RGLS | Class A-2 Convertible Preferred Stock | I | 6,6600 | 900.900 | 6.000 | 900.900 | ||||
| 2019-12-26 | 2019-12-24 | 4 | Walker Paul Edward See Note 1 | RGLS | Common Stock Purchase Warrant (Right to Buy) | I | 0,67 | 0,1250 | 9.009.000 | 1.126 | 9.009.000 | |||
| 2019-12-26 | 2019-12-24 | 4 | Growth Equity Opportunities V, LLC | RGLS | Class A-2 Convertible Preferred Stock | D | 6,6600 | 900.900 | 6.000 | 900.900 | ||||
| 2019-12-26 | 2019-12-24 | 4 | Growth Equity Opportunities V, LLC | RGLS | Common Stock Purchase Warrant (Right to Buy) | D | 0,67 | 0,1250 | 9.009.000 | 1.126 | 9.009.000 | |||
| 2019-12-26 | 2019-12-24 | 4 | BARRIS PETER J See Note 1 | RGLS | Class A-2 Convertible Preferred Stock | I | 6,6600 | 900.900 | 6.000 | 900.900 | ||||
| 2019-12-26 | 2019-12-24 | 4 | BARRIS PETER J See Note 1 | RGLS | Common Stock Purchase Warrant (Right to Buy) | I | 0,67 | 0,1250 | 9.009.000 | 1.126 | 9.009.000 | |||
| 2019-12-26 | 2019-12-24 | 4 | BASKETT FOREST See Note 1 | RGLS | Class A-2 Convertible Preferred Stock | I | 6,6600 | 900.900 | 6.000 | 900.900 | ||||
| 2019-12-26 | 2019-12-24 | 4 | BASKETT FOREST See Note 1 | RGLS | Common Stock Purchase Warrant (Right to Buy) | I | 0,67 | 0,1250 | 9.009.000 | 1.126 | 9.009.000 | |||
| 2019-12-26 | 2019-12-24 | 4 | Behbahani Ali See Note 1 | RGLS | Class A-2 Convertible Preferred Stock | I | 6,6600 | 900.900 | 6.000 | 900.900 | ||||
| 2019-12-26 | 2019-12-24 | 4 | Behbahani Ali See Note 1 | RGLS | Common Stock Purchase Warrant (Right to Buy) | I | 0,67 | 0,1250 | 9.009.000 | 1.126 | 9.009.000 | |||
| 2019-12-26 | 2019-12-24 | 4 | Chang Carmen See Note 1 | RGLS | Class A-2 Convertible Preferred Stock | I | 6,6600 | 900.900 | 6.000 | 900.900 | ||||
| 2019-12-26 | 2019-12-24 | 4 | Chang Carmen See Note 1 | RGLS | Common Stock Purchase Warrant (Right to Buy) | I | 0,67 | 0,1250 | 9.009.000 | 1.126 | 9.009.000 | |||
| 2019-12-26 | 2019-12-24 | 4 | Florence Anthony A. Jr. See Note 1 | RGLS | Class A-2 Convertible Preferred Stock | I | 6,6600 | 900.900 | 6.000 | 900.900 | ||||
| 2019-12-26 | 2019-12-24 | 4 | Florence Anthony A. Jr. See Note 1 | RGLS | Common Stock Purchase Warrant (Right to Buy) | I | 0,67 | 0,1250 | 9.009.000 | 1.126 | 9.009.000 | |||
| 2019-12-26 | 2019-12-24 | 4 | Makhzoumi Mohamad See Note 1 | RGLS | Class A-2 Convertible Preferred Stock | I | 6,6600 | 900.900 | 6.000 | 900.900 | ||||
| 2019-12-26 | 2019-12-24 | 4 | Makhzoumi Mohamad See Note 1 | RGLS | Common Stock Purchase Warrant (Right to Buy) | I | 0,67 | 0,1250 | 9.009.000 | 1.126 | 9.009.000 | |||
| 2019-12-26 | 2019-12-24 | 4 | MAKOWER JOSHUA See Note 1 | RGLS | Class A-2 Convertible Preferred Stock | I | 6,6600 | 900.900 | 6.000 | 900.900 | ||||
| 2019-12-26 | 2019-12-24 | 4 | MAKOWER JOSHUA See Note 1 | RGLS | Common Stock Purchase Warrant (Right to Buy) | I | 0,67 | 0,1250 | 9.009.000 | 1.126 | 9.009.000 | |||
| 2019-12-26 | 2019-12-24 | 4 | MOTT DAVID M See Note 1 | RGLS | Class A-2 Convertible Preferred Stock | I | 6,6600 | 900.900 | 6.000 | 900.900 | ||||
| 2019-12-26 | 2019-12-24 | 4 | MOTT DAVID M See Note 1 | RGLS | Common Stock Purchase Warrant (Right to Buy) | I | 0,67 | 0,1250 | 9.009.000 | 1.126 | 9.009.000 | |||
| 2019-12-26 | 2019-12-24 | 4 | Hagan Joseph P PENSCO TRUST CO OBO JOSEPH HAGAN IRA | RGLS | Common Stock Purchase Warrant (Right to Buy) | I | 0,67 | 0,1250 | 75.850 | 9 | 75.850 | |||
| 2019-12-26 | 2019-12-24 | 4 | Hagan Joseph P PENSCO TRUST CO OBO JOSEPH HAGAN IRA | RGLS | Class A-2 Convertible Preferred Stock | I | 6,6600 | 7.585 | 51 | 7.585 | ||||
| 2019-12-26 | 2019-12-24 | 4 | RASTETTER WILLIAM H THE RASTETTER FAMILY TRUST DTD 9-2-2010 | RGLS | Common Stock Purchase Warrant (Right to Buy) | I | 0,67 | 0,1250 | 225.940 | 28 | 225.940 | |||
| 2019-12-26 | 2019-12-24 | 4 | RASTETTER WILLIAM H THE RASTETTER FAMILY TRUST DTD 9-2-2010 | RGLS | Class A-2 Convertible Preferred Stock | I | 6,6600 | 22.594 | 150 | 22.594 | ||||
| 2019-12-26 | 2019-12-24 | 4 | Witz Pascale | RGLS | Common Stock Purchase Warrant (Right to Buy) | D | 0,67 | 0,1250 | 67.700 | 8 | 67.700 | |||
| 2019-12-26 | 2019-12-24 | 4 | Witz Pascale | RGLS | Class A-2 Convertible Preferred Stock | D | 6,6600 | 6.770 | 45 | 6.770 | ||||
| 2019-12-26 | 2019-12-24 | 4 | PAPADOPOULOS STELIOS | RGLS | Common Stock Purchase Warrant (Right to Buy) | D | 0,67 | 0,1250 | 846.320 | 106 | 846.320 | |||
| 2019-12-26 | 2019-12-24 | 4 | PAPADOPOULOS STELIOS | RGLS | Class A-2 Convertible Preferred Stock | D | 6,6600 | 84.632 | 564 | 84.632 | ||||
| 2019-11-15 | 2019-11-14 | 4 | Hagan Joseph P | RGLS | Common Stock | D | 0,6400 | -5.838 | -4 | 243.428 | ||||
| 2019-11-15 | 2019-11-14 | 4 | Aker Christopher Ray | RGLS | Common Stock | D | 0,6400 | -833 | -1 | 31.546 | ||||
| 2019-10-15 | 2019-10-10 | 4 | Aker Christopher Ray | RGLS | Stock Option (Right to Buy) | D | 0,64 | 335.000 | 335.000 | |||||
| 2019-10-15 | 2019-10-10 | 4 | BALTIMORE DAVID | RGLS | Stock Option (Right to Buy) | D | 0,64 | 46.500 | 46.500 | |||||
| 2019-10-15 | 2019-10-10 | 4 | CALSADA CRISPINA | RGLS | Stock Option (Right to Buy) | D | 0,64 | 210.000 | 210.000 | |||||
| 2019-10-15 | 2019-10-10 | 4 | Collier Kathryn J | RGLS | Stock Option (Right to Buy) | D | 0,64 | 46.500 | 46.500 | |||||
| 2019-10-15 | 2019-10-10 | 4 | Hagan Joseph P | RGLS | Stock Option (Right to Buy) | D | 0,64 | 1.000.000 | 1.000.000 | |||||
| 2019-10-15 | 2019-10-10 | 4 | Nunn Jason Raleigh | RGLS | Stock Option (Right to Buy) | D | 0,64 | 46.500 | 46.500 | |||||
| 2019-10-15 | 2019-10-10 | 4 | PAPADOPOULOS STELIOS | RGLS | Stock Option (Right to Buy) | D | 0,64 | 46.500 | 46.500 | |||||
| 2019-10-15 | 2019-10-10 | 4 | RASTETTER WILLIAM H THE RASTETTER FAMILY TRUST DTD 9-2-2010 | RGLS | Stock Option (Right to Buy) | I | 0,64 | 46.500 | 46.500 | |||||
| 2019-10-15 | 2019-10-10 | 4 | Rosen Hugh | RGLS | Stock Option (Right to Buy) | D | 0,64 | 46.500 | 46.500 | |||||
| 2019-10-15 | 2019-10-10 | 4 | Simeonidis Simos | RGLS | Stock Option (Right to Buy) | D | 0,64 | 46.500 | 46.500 | |||||
| 2019-10-15 | 2019-10-10 | 4 | Witz Pascale | RGLS | Stock Option (Right to Buy) | D | 0,64 | 46.500 | 46.500 | |||||
| 2019-10-02 | 2019-10-01 | 4 | Hagan Joseph P | RGLS | Common Stock | D | 0,6827 | -8.743 | -6 | 249.266 | ||||
| 2019-10-02 | 2019-10-01 | 4 | Aker Christopher Ray | RGLS | Common Stock | D | 0,6827 | -2.346 | -2 | 32.379 | ||||
| 2019-09-03 | 2019-08-30 | 4 | CALSADA CRISPINA | RGLS | Stock Option (Right to Buy) | D | 0,62 | 100.000 | 100.000 | |||||
| 2019-08-16 | 2019-08-15 | 4 | Aker Christopher Ray | RGLS | Common Stock | D | 0,5506 | -899 | -0 | 34.725 | ||||
| 2019-08-16 | 2019-08-15 | 4 | Hagan Joseph P | RGLS | Common Stock | D | 0,5506 | -4.375 | -2 | 258.009 | ||||
| 2019-07-02 | 2019-07-01 | 4 | Chevallard Daniel R. | RGLS | Common Stock | D | 1,3115 | -2.669 | -4 | 77.870 | ||||
| 2019-07-02 | 2019-07-01 | 4 | Aker Christopher Ray | RGLS | Common Stock | D | 1,3115 | -2.225 | -3 | 35.624 | ||||
| 2019-07-02 | 2019-07-01 | 4 | Hagan Joseph P | RGLS | Common Stock | D | 1,3115 | -5.783 | -8 | 262.384 | ||||
| 2019-06-11 | 3 | Simeonidis Simos By Sarissa Capital | RGLS | Common Stock | I | 3.703.702 | ||||||||
| 2019-06-11 | 3 | Simeonidis Simos By Sarissa Capital | RGLS | Common Stock | I | 3.703.702 | ||||||||
| 2019-06-11 | 3 | Simeonidis Simos By Sarissa Capital | RGLS | Common Stock | I | 3.703.702 | ||||||||
| 2019-05-21 | 2019-05-07 | 4/A | Hagan Joseph P | RGLS | Common Stock Purchase Warrant (Right to Buy) | D | 1,08 | 0,1250 | 33.194 | 4 | 33.194 | |||
| 2019-05-21 | 2019-05-07 | 4/A | Hagan Joseph P | RGLS | Common Stock | D | 1,0800 | 33.194 | 36 | 64.542 | ||||
| 2019-05-21 | 2019-05-07 | 4/A | Witz Pascale | RGLS | Common Stock Purchase Warrant (Right to Buy) | D | 1,08 | 0,1250 | 29.630 | 4 | 29.630 | |||
| 2019-05-21 | 2019-05-07 | 4/A | Witz Pascale | RGLS | Common Stock | D | 1,0800 | 29.630 | 32 | 37.849 | ||||
| 2019-05-21 | 2019-05-07 | 4/A | RASTETTER WILLIAM H The Rastetter Family Trust DTD 9-2-2010 | RGLS | Common Stock Purchase Warrant (Right to Buy) | I | 1,08 | 0,1250 | 92.889 | 12 | 92.889 | |||
| 2019-05-21 | 2019-05-07 | 4/A | RASTETTER WILLIAM H The Rastetter Family Trust DTD 9-2-2010 | RGLS | Common Stock | I | 1,0800 | 92.889 | 100 | 154.223 | ||||
| 2019-05-21 | 2019-05-07 | 4/A | PAPADOPOULOS STELIOS | RGLS | Common Stock Purchase Warrant (Right to Buy) | D | 1,08 | 0,1250 | 370.370 | 46 | 370.370 | |||
| 2019-05-21 | 2019-05-07 | 4/A | PAPADOPOULOS STELIOS | RGLS | Common Stock | D | 1,0800 | 370.370 | 400 | 1.189.872 | ||||
| 2019-05-17 | 3 | Sarissa Capital Offshore Master Fund LP See Footnotes | RGLS | Common Stock | I | 3.703.702 | ||||||||
| 2019-05-17 | 3 | Sarissa Capital Offshore Master Fund LP See Footnotes | RGLS | Common Stock | I | 3.703.702 | ||||||||
| 2019-05-17 | 3 | Sarissa Capital Offshore Master Fund LP See Footnotes | RGLS | Common Stock | I | 3.703.702 | ||||||||
| 2019-05-17 | 3 | Sarissa Capital Offshore Master Fund LP See Footnotes | RGLS | Common Stock | I | 3.703.702 | ||||||||
| 2019-05-17 | 3 | Sarissa Capital Offshore Master Fund LP See Footnotes | RGLS | Common Stock | I | 3.703.702 | ||||||||
| 2019-05-17 | 3 | Sarissa Capital Offshore Master Fund LP See Footnotes | RGLS | Common Stock | I | 3.703.702 | ||||||||
| 2019-05-17 | 3 | Sarissa Capital Offshore Master Fund LP See Footnotes | RGLS | Common Stock | I | 3.703.702 | ||||||||
| 2019-05-16 | 2019-05-14 | 4/A | Chevallard Daniel R. | RGLS | Stock Option (Right to Buy) | D | 0,95 | 8.000 | 8.000 | |||||
| 2019-05-16 | 2019-05-15 | 4 | Aker Christopher Ray | RGLS | Common Stock | D | 1,4095 | -6.950 | -10 | 59.309 | ||||
| 2019-05-16 | 2019-05-14 | 4 | Aker Christopher Ray | RGLS | Stock Option (Right to Buy) | D | 0,95 | 7.500 | 7.500 | |||||
| 2019-05-16 | 2019-05-14 | 4 | Aker Christopher Ray | RGLS | Common Stock | D | 38.512 | 66.259 | ||||||
| 2019-05-16 | 2019-05-15 | 4 | Chevallard Daniel R. | RGLS | Common Stock | D | 1,4089 | -10.000 | -14 | 80.539 | ||||
| 2019-05-16 | 2019-05-14 | 4 | Chevallard Daniel R. | RGLS | Stock Option (Right to Buy) | D | 0,95 | 8.000 | 7.500 | |||||
| 2019-05-16 | 2019-05-14 | 4 | Chevallard Daniel R. | RGLS | Common Stock | D | 55.414 | 90.539 | ||||||
| 2019-05-16 | 2019-05-16 | 4 | Hagan Joseph P | RGLS | Common Stock | D | 1,2189 | -39.352 | -48 | 268.167 | ||||
| 2019-05-16 | 2019-05-14 | 4 | Hagan Joseph P | RGLS | Stock Option (Right to Buy) | D | 0,95 | 10.000 | 10.000 | |||||
| 2019-05-16 | 2019-05-14 | 4 | Hagan Joseph P | RGLS | Common Stock | D | 188.385 | 307.519 | ||||||
| 2019-05-10 | 2019-05-07 | 4/A | Walker Paul Edward See Note 2 | RGLS | Class A-1 Convertible Preferred Stock | I | 10,8000 | 256.700 | 2.772 | 256.700 | ||||
| 2019-05-10 | 2019-05-07 | 4/A | Walker Paul Edward See Note 2 | RGLS | Common Stock Purchase Warrant (Right to Buy) | I | 1,08 | 0,1250 | 3.703.704 | 463 | 3.703.704 | |||
| 2019-05-10 | 2019-05-07 | 4/A | Walker Paul Edward See Note 2 | RGLS | Common Stock | I | 1,0800 | 1.136.704 | 1.228 | 2.052.454 | ||||
| 2019-05-09 | 2019-05-07 | 4 | Growth Equity Opportunities V, LLC | RGLS | Class A-1 Convertible Preferred Stock | D | 10,8000 | 256.700 | 2.772 | 256.700 | ||||
| 2019-05-09 | 2019-05-07 | 4 | Growth Equity Opportunities V, LLC | RGLS | Common Stock Purchase Warrant (Right to Buy) | D | 1,08 | 0,1250 | 3.703.704 | 463 | 3.703.704 | |||
| 2019-05-09 | 2019-05-07 | 4 | Growth Equity Opportunities V, LLC | RGLS | Common Stock | D | 1,0800 | 1.136.704 | 1.228 | 2.052.454 | ||||
| 2019-05-09 | 2019-05-07 | 4 | BARRIS PETER J See Note 2 | RGLS | Class A-1 Convertible Preferred Stock | I | 10,8000 | 256.700 | 2.772 | 256.700 | ||||
| 2019-05-09 | 2019-05-07 | 4 | BARRIS PETER J See Note 2 | RGLS | Common Stock Purchase Warrant (Right to Buy) | I | 1,08 | 0,1250 | 3.703.704 | 463 | 3.703.704 | |||
| 2019-05-09 | 2019-05-07 | 4 | BARRIS PETER J See Note 2 | RGLS | Common Stock | I | 1,0800 | 1.136.704 | 1.228 | 2.052.454 | ||||
| 2019-05-09 | 2019-05-07 | 4 | BASKETT FOREST See Note 2 | RGLS | Class A-1 Convertible Preferred Stock | I | 10,8000 | 256.700 | 2.772 | 256.700 | ||||
| 2019-05-09 | 2019-05-07 | 4 | BASKETT FOREST See Note 2 | RGLS | Common Stock Purchase Warrant (Right to Buy) | I | 1,08 | 0,1250 | 3.703.704 | 463 | 3.703.704 | |||
| 2019-05-09 | 2019-05-07 | 4 | BASKETT FOREST See Note 2 | RGLS | Common Stock | I | 1,0800 | 1.136.704 | 1.228 | 2.052.454 | ||||
| 2019-05-09 | 2019-05-07 | 4 | Behbahani Ali See Note 2 | RGLS | Class A-1 Convertible Preferred Stock | I | 10,8000 | 256.700 | 2.772 | 256.700 | ||||
| 2019-05-09 | 2019-05-07 | 4 | Behbahani Ali See Note 2 | RGLS | Common Stock Purchase Warrant (Right to Buy) | I | 1,08 | 0,1250 | 3.703.704 | 463 | 3.703.704 | |||
| 2019-05-09 | 2019-05-07 | 4 | Behbahani Ali See Note 2 | RGLS | Common Stock | I | 1,0800 | 1.136.704 | 1.228 | 2.052.454 | ||||
| 2019-05-09 | 2019-05-07 | 4 | Chang Carmen See Note 2 | RGLS | Class A-1 Convertible Preferred Stock | I | 10,8000 | 256.700 | 2.772 | 256.700 | ||||
| 2019-05-09 | 2019-05-07 | 4 | Chang Carmen See Note 2 | RGLS | Common Stock Purchase Warrant (Right to Buy) | I | 1,08 | 0,1250 | 3.703.704 | 463 | 3.703.704 | |||
| 2019-05-09 | 2019-05-07 | 4 | Chang Carmen See Note 2 | RGLS | Common Stock | I | 1,0800 | 1.136.704 | 1.228 | 2.052.454 | ||||
| 2019-05-09 | 2019-05-07 | 4 | Florence Anthony A. Jr. See Note 2 | RGLS | Class A-1 Convertible Preferred Stock | I | 10,8000 | 256.700 | 2.772 | 256.700 | ||||
| 2019-05-09 | 2019-05-07 | 4 | Florence Anthony A. Jr. See Note 2 | RGLS | Common Stock Purchase Warrant (Right to Buy) | I | 1,08 | 0,1250 | 3.703.704 | 463 | 3.703.704 | |||
| 2019-05-09 | 2019-05-07 | 4 | Florence Anthony A. Jr. See Note 2 | RGLS | Common Stock | I | 1,0800 | 1.136.704 | 1.228 | 2.052.454 | ||||
| 2019-05-09 | 2019-05-07 | 4 | Makhzoumi Mohamad See Note 2 | RGLS | Class A-1 Convertible Preferred Stock | I | 10,8000 | 256.700 | 2.772 | 256.700 | ||||
| 2019-05-09 | 2019-05-07 | 4 | Makhzoumi Mohamad See Note 2 | RGLS | Common Stock Purchase Warrant (Right to Buy) | I | 1,08 | 0,1250 | 3.703.704 | 463 | 3.703.704 | |||
| 2019-05-09 | 2019-05-07 | 4 | Makhzoumi Mohamad See Note 2 | RGLS | Common Stock | I | 1,0800 | 1.136.704 | 1.228 | 2.052.454 | ||||
| 2019-05-09 | 2019-05-07 | 4 | MAKOWER JOSHUA See Note 2 | RGLS | Class A-1 Convertible Preferred Stock | I | 10,8000 | 256.700 | 2.772 | 256.700 | ||||
| 2019-05-09 | 2019-05-07 | 4 | MAKOWER JOSHUA See Note 2 | RGLS | Common Stock Purchase Warrant (Right to Buy) | I | 1,08 | 0,1250 | 3.703.704 | 463 | 3.703.704 | |||
| 2019-05-09 | 2019-05-07 | 4 | MAKOWER JOSHUA See Note 2 | RGLS | Common Stock | I | 1,0800 | 1.136.704 | 1.228 | 2.052.454 | ||||
| 2019-05-09 | 2019-05-07 | 4 | MOTT DAVID M See Note 2 | RGLS | Class A-1 Convertible Preferred Stock | I | 10,8000 | 256.700 | 2.772 | 256.700 | ||||
| 2019-05-09 | 2019-05-07 | 4 | MOTT DAVID M See Note 2 | RGLS | Common Stock Purchase Warrant (Right to Buy) | I | 1,08 | 0,1250 | 3.703.704 | 463 | 3.703.704 | |||
| 2019-05-09 | 2019-05-07 | 4 | MOTT DAVID M See Note 2 | RGLS | Common Stock | I | 1,0800 | 1.136.704 | 1.228 | 2.052.454 | ||||
| 2019-05-09 | 2019-05-07 | 4 | SANDELL SCOTT D See Note 2 | RGLS | Class A-1 Convertible Preferred Stock | I | 10,8000 | 256.700 | 2.772 | 256.700 | ||||
| 2019-05-09 | 2019-05-07 | 4 | SANDELL SCOTT D See Note 2 | RGLS | Common Stock Purchase Warrant (Right to Buy) | I | 1,08 | 0,1250 | 3.703.704 | 463 | 3.703.704 | |||
| 2019-05-09 | 2019-05-07 | 4 | SANDELL SCOTT D See Note 2 | RGLS | Common Stock | I | 1,0800 | 1.136.704 | 1.228 | 2.052.454 | ||||
| 2019-05-09 | 2019-05-07 | 4 | Sonsini Peter W. See Note 2 | RGLS | Class A-1 Convertible Preferred Stock | I | 10,8000 | 256.700 | 2.772 | 256.700 | ||||
| 2019-05-09 | 2019-05-07 | 4 | Sonsini Peter W. See Note 2 | RGLS | Common Stock Purchase Warrant (Right to Buy) | I | 1,08 | 0,1250 | 3.703.704 | 463 | 3.703.704 | |||
| 2019-05-09 | 2019-05-07 | 4 | Sonsini Peter W. See Note 2 | RGLS | Common Stock | I | 1,0800 | 1.136.704 | 1.228 | 2.052.454 | ||||
| 2019-05-09 | 2019-05-07 | 4 | Walker Paul Edward See Note 2 | RGLS | Class A-1 Convertible Preferred Stock | I | 10,8000 | 256.700 | 2.772 | 256.700 | ||||
| 2019-05-09 | 2019-05-07 | 4 | Walker Paul Edward See Note 2 | RGLS | Common Stock Purchase Warrant (Right to Buy) | I | 1,08 | 0,1250 | 3.703.704 | 463 | 3.703.704 | |||
| 2019-05-09 | 2019-05-07 | 4 | Walker Paul Edward See Note 2 | RGLS | Common Stock | I | 1,0800 | 1.136.704 | 1.228 | 2.052.454 | ||||
| 2019-05-08 | 2019-05-07 | 4 | PAPADOPOULOS STELIOS | RGLS | Common Stock Purchase Warrant (Right to Buy) | D | 1,08 | 0,1250 | 370.370 | 46 | 370.370 | |||
| 2019-05-08 | 2019-05-07 | 4 | PAPADOPOULOS STELIOS | RGLS | Common Stock | D | 1,0800 | 370.370 | 400 | 1.189.872 | ||||
| 2019-05-08 | 2019-05-07 | 4 | RASTETTER WILLIAM H THE RASTETTER FAMILY TRUST DTD 09-02-2010 | RGLS | Common Stock Purchase Warrant (Right to Buy) | I | 1,08 | 0,1250 | 92.889 | 12 | 92.889 | |||
| 2019-05-08 | 2019-05-07 | 4 | RASTETTER WILLIAM H THE RASTETTER FAMILY TRUST DTD 9-2-2010 | RGLS | Common Stock | I | 1,0800 | 92.889 | 100 | 154.223 | ||||
| 2019-05-08 | 2019-05-07 | 4 | Witz Pascale | RGLS | Common Stock Purchase Warrant (Right to Buy) | D | 1,08 | 0,1250 | 29.630 | 4 | 29.630 | |||
| 2019-05-08 | 2019-05-07 | 4 | Witz Pascale | RGLS | Common Stock | D | 1,0800 | 29.630 | 32 | 37.849 | ||||
| 2019-05-08 | 2019-05-07 | 4 | Hagan Joseph P | RGLS | Common Stock Purchase Warrant (Right to Buy) | D | 1,08 | 0,1250 | 33.194 | 4 | 33.194 | |||
| 2019-05-08 | 2019-05-07 | 4 | Hagan Joseph P | RGLS | Common Stock | D | 1,0800 | 33.194 | 36 | 64.542 | ||||
| 2019-04-03 | 2019-04-01 | 4 | Hagan Joseph P | RGLS | Common Stock | D | 0,9810 | -5.842 | -6 | 31.348 | ||||
| 2019-04-03 | 2019-04-01 | 4 | Aker Christopher Ray | RGLS | Common Stock | D | 0,9812 | -2.710 | -3 | 6.287 | ||||
| 2019-04-03 | 2019-04-01 | 4 | Chevallard Daniel R. | RGLS | Common Stock | D | 0,9814 | -3.253 | -3 | 9.372 | ||||
| 2019-02-06 | 2019-02-05 | 4 | Aker Christopher Ray | RGLS | Stock Option (Right to Buy) | D | 0,95 | 25.000 | 25.000 | |||||
| 2019-02-06 | 2019-02-05 | 4 | Aker Christopher Ray | RGLS | Common Stock | D | 25.000 | 27.747 | ||||||
| 2019-02-06 | 2019-02-05 | 4 | Chevallard Daniel R. | RGLS | Stock Option (Right to Buy) | D | 0,95 | 30.000 | 30.000 | |||||
| 2019-02-06 | 2019-02-05 | 4 | Chevallard Daniel R. | RGLS | Common Stock | D | 0,9500 | 30.000 | 28 | 34.578 | ||||
| 2019-02-06 | 2019-02-05 | 4 | Hagan Joseph P | RGLS | Stock Option (Right to Buy) | D | 0,95 | 65.000 | 65.000 | |||||
| 2019-02-06 | 2019-02-05 | 4 | Hagan Joseph P | RGLS | Common Stock | D | 0,9500 | 65.000 | 62 | 84.148 | ||||
| 2019-02-06 | 2019-02-05 | 4 | WRIGHT TIMOTHY MICHAEL | RGLS | Stock Option (Right to Buy) | D | 0,95 | 40.000 | 40.000 | |||||
| 2019-02-06 | 2019-02-05 | 4 | WRIGHT TIMOTHY MICHAEL | RGLS | Common Stock | D | 0,9500 | 40.000 | 38 | 62.893 | ||||
| 2019-01-02 | 3 | Aker Christopher Ray | RGLS | Common Stock | D | 5.494 | ||||||||
| 2019-01-02 | 3 | Aker Christopher Ray | RGLS | Common Stock | D | 5.494 | ||||||||
| 2019-01-02 | 3 | Aker Christopher Ray | RGLS | Common Stock | D | 5.494 | ||||||||
| 2019-01-02 | 2018-12-28 | 4 | PAPADOPOULOS STELIOS | RGLS | Common Stock | D | 1,0914 | 50.000 | 55 | 835.073 | ||||
| 2018-12-28 | 2018-12-27 | 4 | PAPADOPOULOS STELIOS | RGLS | Common Stock | D | 1,0401 | 26.401 | 27 | 785.073 | ||||
| 2018-12-28 | 2018-12-26 | 4 | PAPADOPOULOS STELIOS | RGLS | Common Stock | D | 0,9542 | 90.000 | 86 | 758.672 | ||||
| 2018-11-21 | 2018-11-12 | 4 | PAPADOPOULOS STELIOS | RGLS | Stock Option (Right to Buy) | D | 8,76 | -4.583 | 0 | |||||
| 2018-11-21 | 2018-11-12 | 4 | PAPADOPOULOS STELIOS | RGLS | Stock Option (Right to Buy) | D | 8,52 | -6.250 | 0 | |||||
| 2018-11-21 | 2018-11-12 | 4 | PAPADOPOULOS STELIOS | RGLS | Stock Option (Right to Buy) | D | 17,40 | -2.500 | 0 | |||||
| 2018-11-21 | 2018-11-12 | 4 | PAPADOPOULOS STELIOS | RGLS | Stock Option (Right to Buy) | D | 74,40 | -3.051 | 0 | |||||
| 2018-11-21 | 2018-11-12 | 4 | PAPADOPOULOS STELIOS | RGLS | Stock Option (Right to Buy) | D | 111,84 | -1.458 | 0 | |||||
| 2018-11-21 | 2018-11-12 | 4 | PAPADOPOULOS STELIOS | RGLS | Stock Option (Right to Buy) | D | 120,24 | -1.458 | 0 | |||||
| 2018-11-21 | 2018-11-12 | 4 | PAPADOPOULOS STELIOS | RGLS | Stock Option (Right to Buy) | D | 74,64 | -1.458 | 0 | |||||
| 2018-11-21 | 2018-11-12 | 4 | PAPADOPOULOS STELIOS | RGLS | Stock Option (Right to Buy) | D | 31,92 | -152 | 0 | |||||
| 2018-11-21 | 2018-11-12 | 4 | PAPADOPOULOS STELIOS | RGLS | Common Stock | D | 20.910 | 168.672 | ||||||
| 2018-11-19 | 2018-11-16 | 4 | Collier Kathryn J | RGLS | Common Stock | D | 1,4100 | 7.100 | 10 | 27.596 | ||||
| 2018-11-19 | 2018-11-16 | 4 | PAPADOPOULOS STELIOS | RGLS | Common Stock | D | 1,3849 | 300.000 | 415 | 668.672 | ||||
| 2018-11-19 | 2018-11-15 | 4 | PAPADOPOULOS STELIOS | RGLS | Common Stock | D | 1,3254 | 200.000 | 265 | 368.672 | ||||
| 2018-11-13 | 2018-11-12 | 4 | Witz Pascale | RGLS | Stock Option (Right to Buy) | D | 8,76 | -4.583 | 0 | |||||
| 2018-11-13 | 2018-11-12 | 4 | Witz Pascale | RGLS | Stock Option (Right to Buy) | D | 8,52 | -6.250 | 0 | |||||
| 2018-11-13 | 2018-11-12 | 4 | Witz Pascale | RGLS | Stock Option (Right to Buy) | D | 17,40 | -5.000 | 0 | |||||
| 2018-11-13 | 2018-11-12 | 4 | Witz Pascale | RGLS | Common Stock | D | 15.833 | 19.625 | ||||||
| 2018-11-13 | 2018-11-12 | 4 | Rosen Hugh | RGLS | Stock Option (Right to Buy) | D | 8,76 | -4.583 | 0 | |||||
| 2018-11-13 | 2018-11-12 | 4 | Rosen Hugh | RGLS | Stock Option (Right to Buy) | D | 8,52 | -6.250 | 0 | |||||
| 2018-11-13 | 2018-11-12 | 4 | Rosen Hugh | RGLS | Stock Option (Right to Buy) | D | 17,40 | -2.500 | 0 | |||||
| 2018-11-13 | 2018-11-12 | 4 | Rosen Hugh | RGLS | Stock Option (Right to Buy) | D | 74,40 | -5.912 | 0 | |||||
| 2018-11-13 | 2018-11-12 | 4 | Rosen Hugh | RGLS | Common Stock | D | 19.245 | 22.756 | ||||||
| 2018-11-13 | 2018-11-12 | 4 | RASTETTER WILLIAM H William H. Rastetter TTEE, Marisa Rastetter TTEE 9-2-2010 FBO Rastetter Family Trus | RGLS | Stock Option (Right to Buy) | I | 8,76 | -4.583 | 0 | |||||
| 2018-11-13 | 2018-11-12 | 4 | RASTETTER WILLIAM H William H. Rastetter TTEE, Marisa Rastetter TTEE 9-2-2010 FBO Rastetter Family Trus | RGLS | Stock Option (Right to Buy) | I | 8,52 | -6.250 | 0 | |||||
| 2018-11-13 | 2018-11-12 | 4 | RASTETTER WILLIAM H William H. Rastetter TTEE, Marisa Rastetter TTEE 9-2-2010 FBO Rastetter Family Trus | RGLS | Stock Option (Right to Buy) | I | 17,40 | -2.500 | 0 | |||||
| 2018-11-13 | 2018-11-12 | 4 | RASTETTER WILLIAM H William H. Rastetter TTEE, Marisa Rastetter TTEE 9-2-2010 FBO Rastetter Family Trus | RGLS | Stock Option (Right to Buy) | I | 92,04 | -2.500 | 0 | |||||
| 2018-11-13 | 2018-11-12 | 4 | RASTETTER WILLIAM H William H. Rastetter TTEE, Marisa Rastetter TTEE 9-2-2010 FBO Rastetter Family Trus | RGLS | Stock Option (Right to Buy) | I | 74,40 | -3.051 | 0 | |||||
| 2018-11-13 | 2018-11-12 | 4 | RASTETTER WILLIAM H William H. Rastetter TTEE, Marisa Rastetter TTEE 9-2-2010 FBO Rastetter Family Trus | RGLS | Stock Option (Right to Buy) | I | 120,24 | -1.458 | 0 | |||||
| 2018-11-13 | 2018-11-12 | 4 | RASTETTER WILLIAM H William H. Rastetter TTEE, Marisa Rastetter TTEE 9-2-2010 FBO Rastetter Family Trus | RGLS | Stock Option (Right to Buy) | I | 111,84 | -1.458 | 0 | |||||
| 2018-11-13 | 2018-11-12 | 4 | RASTETTER WILLIAM H William H. Rastetter TTEE, Marisa Rastetter TTEE 9-2-2010 FBO Rastetter Family Trus | RGLS | Stock Option (Right to Buy) | I | 74,64 | -1.458 | 0 | |||||
| 2018-11-13 | 2018-11-12 | 4 | RASTETTER WILLIAM H William H. Rastetter TTEE, Marisa Rastetter TTEE 9-2-2010 FBO Rastetter Family Trust | RGLS | Common Stock | I | 23.258 | 79.672 | ||||||
| 2018-11-13 | 2018-11-12 | 4 | Collier Kathryn J | RGLS | Stock Option (Right to Buy) | D | 8,67 | -4.583 | 0 | |||||
| 2018-11-13 | 2018-11-12 | 4 | Collier Kathryn J | RGLS | Stock Option (Right to Buy) | D | 8,52 | -3.125 | 0 | |||||
| 2018-11-13 | 2018-11-12 | 4 | Collier Kathryn J | RGLS | Stock Option (Right to Buy) | D | 9,45 | -9.166 | 0 | |||||
| 2018-11-13 | 2018-11-12 | 4 | Collier Kathryn J | RGLS | Common Stock | D | 16.874 | 20.496 | ||||||
| 2018-11-13 | 2018-11-12 | 4 | BALTIMORE DAVID | RGLS | Stock Option (Right to Buy) | D | 8,76 | -4.583 | 0 | |||||
| 2018-11-13 | 2018-11-12 | 4 | BALTIMORE DAVID | RGLS | Stock Option (Right to Buy) | D | 8,52 | -6.250 | 0 | |||||
| 2018-11-13 | 2018-11-12 | 4 | BALTIMORE DAVID | RGLS | Stock Option (Right to Buy) | D | 17,40 | -2.500 | 0 | |||||
| 2018-11-13 | 2018-11-12 | 4 | BALTIMORE DAVID | RGLS | Stock Option (Right to Buy) | D | 74,40 | -3.051 | 0 | |||||
| 2018-11-13 | 2018-11-12 | 4 | BALTIMORE DAVID | RGLS | Stock Option (Right to Buy) | D | 120,24 | -1.458 | 0 | |||||
| 2018-11-13 | 2018-11-12 | 4 | BALTIMORE DAVID | RGLS | Stock Option (Right to Buy) | D | 4,56 | -1.458 | 0 | |||||
| 2018-11-13 | 2018-11-12 | 4 | BALTIMORE DAVID | RGLS | Stock Option (Right to Buy) | D | 74,64 | -416 | 0 | |||||
| 2018-11-13 | 2018-11-12 | 4 | BALTIMORE DAVID | RGLS | Stock Option (Right to Buy) | D | 111,84 | -416 | 0 | |||||
| 2018-11-13 | 2018-11-12 | 4 | BALTIMORE DAVID | RGLS | Stock Option (Right to Buy) | D | 74,64 | -1.458 | 0 | |||||
| 2018-11-13 | 2018-11-12 | 4 | BALTIMORE DAVID | RGLS | Stock Option (Right to Buy) | D | 111,84 | -1.458 | 0 | |||||
| 2018-11-13 | 2018-11-12 | 4 | BALTIMORE DAVID | RGLS | Stock Option (Right to Buy) | D | 31,92 | -1.458 | 0 | |||||
| 2018-11-13 | 2018-11-12 | 4 | BALTIMORE DAVID | RGLS | Stock Option (Right to Buy) | D | 4,56 | -625 | 0 | |||||
| 2018-11-13 | 2018-11-12 | 4 | BALTIMORE DAVID | RGLS | Stock Option (Right to Buy) | D | 31,92 | -625 | 0 | |||||
| 2018-11-13 | 2018-11-12 | 4 | BALTIMORE DAVID | RGLS | Stock Option (Right to Buy) | D | 20,88 | -1.458 | 0 | |||||
| 2018-11-13 | 2018-11-12 | 4 | BALTIMORE DAVID | RGLS | Stock Option (Right to Buy) | D | 20,88 | -625 | 0 | |||||
| 2018-11-13 | 2018-11-12 | 4 | BALTIMORE DAVID | RGLS | Stock Option (Right to Buy) | D | 4,56 | -1.875 | 0 | |||||
| 2018-11-13 | 2018-11-12 | 4 | BALTIMORE DAVID | RGLS | Stock Option (Right to Buy) | D | 4,56 | -10.625 | 0 | |||||
| 2018-11-13 | 2018-11-12 | 4 | BALTIMORE DAVID | RGLS | Common Stock | D | 40.339 | 44.131 | ||||||
| 2018-07-17 | 3 | Behbahani Ali See Note 1 | RGLS | Common Stock | I | 21.978.020 | ||||||||
| 2018-07-17 | 3 | Behbahani Ali See Note 1 | RGLS | Common Stock | I | 21.978.020 | ||||||||
| 2018-07-17 | 3 | Behbahani Ali See Note 1 | RGLS | Common Stock | I | 21.978.020 | ||||||||
| 2018-07-17 | 3 | Chang Carmen See Note 1 | RGLS | Common Stock | I | 21.978.020 | ||||||||
| 2018-07-17 | 3 | Chang Carmen See Note 1 | RGLS | Common Stock | I | 21.978.020 | ||||||||
| 2018-07-17 | 3 | Chang Carmen See Note 1 | RGLS | Common Stock | I | 21.978.020 | ||||||||
| 2018-06-05 | 2018-06-05 | 4 | Collier Kathryn J | RGLS | Common Stock | D | 0,7400 | 7.695 | 6 | 7.695 | ||||
| 2018-06-05 | 2018-06-01 | 4 | Collier Kathryn J | RGLS | Stock Option (Right to Buy) | D | 0,73 | 55.000 | 55.000 | |||||
| 2018-06-05 | 2018-06-01 | 4 | BALTIMORE DAVID | RGLS | Stock Option (Right to Buy) | D | 0,73 | 55.000 | 55.000 | |||||
| 2018-06-05 | 2018-06-01 | 4 | PAPADOPOULOS STELIOS | RGLS | Stock Option (Right to Buy) | D | 0,73 | 55.000 | 55.000 | |||||
| 2018-06-05 | 2018-06-01 | 4 | RASTETTER WILLIAM H Rastetter Family Trust dated 9-2-2010 | RGLS | Stock Option (Right to Buy) | I | 0,73 | 55.000 | 55.000 | |||||
| 2018-06-05 | 2018-06-01 | 4 | Rosen Hugh | RGLS | Stock Option (Right to Buy) | D | 0,73 | 55.000 | 55.000 | |||||
| 2018-06-05 | 2018-06-01 | 4 | Witz Pascale | RGLS | Stock Option (Right to Buy) | D | 0,73 | 55.000 | 55.000 | |||||
| 2018-05-21 | 2018-05-17 | 4 | Deeg Mark Albert | RGLS | Common Stock (Right to Buy) | D | 0,71 | 100.000 | 100.000 | |||||
| 2018-05-21 | 2018-05-17 | 4 | Hagan Joseph P | RGLS | Stock Option (Right to Buy) | D | 0,71 | 725.000 | 725.000 | |||||
| 2018-05-21 | 2018-05-17 | 4 | PAPADOPOULOS STELIOS | RGLS | Stock Option (Right to Buy) | D | 0,71 | 75.000 | 75.000 | |||||
| 2018-05-21 | 2018-05-17 | 4 | RASTETTER WILLIAM H Rastetter Family Trust dated 9-2-2010 | RGLS | Stock Option (Right to Buy) | I | 0,71 | 75.000 | 75.000 | |||||
| 2018-05-21 | 2018-05-17 | 4 | Rosen Hugh | RGLS | Stock Option (Right to Buy) | D | 0,71 | 75.000 | 75.000 | |||||
| 2018-05-21 | 2018-05-17 | 4 | Witz Pascale | RGLS | Stock Option (Right to Buy) | D | 0,71 | 75.000 | 75.000 | |||||
| 2018-05-21 | 2018-05-17 | 4 | WRIGHT TIMOTHY MICHAEL | RGLS | Stock Option (Right to Buy) | D | 0,71 | 350.000 | 350.000 | |||||
| 2018-05-21 | 2018-05-17 | 4 | BALTIMORE DAVID | RGLS | Stock Option (Right to Buy) | D | 0,71 | 75.000 | 75.000 | |||||
| 2018-05-21 | 2018-05-17 | 4 | Chevallard Daniel R. | RGLS | Stock Option (Right to Buy) | D | 0,71 | 250.000 | 250.000 | |||||
| 2018-05-21 | 2018-05-17 | 4 | Collier Kathryn J | RGLS | Stock Option (Right to Buy) | D | 0,71 | 37.500 | 37.500 | |||||
| 2018-04-17 | 2018-04-14 | 4 | Collier Kathryn J | RGLS | Stock Option (Right to Buy) | D | 0,64 | 110.000 | 110.000 | |||||
| 2018-04-17 | 2018-04-14 | 4 | Collier Kathryn J | RGLS | Common Stock | D | 0,6400 | 60.234 | 39 | 60.234 | ||||
| 2018-01-05 | 2018-01-05 | 4 | Chevallard Daniel R. | RGLS | Stock Option (Right to Buy) | D | 1,24 | 350.000 | 350.000 | |||||
| 2018-01-05 | 2018-01-05 | 4 | Deeg Mark Albert | RGLS | Stock Option (Right to Buy) | D | 1,24 | 175.000 | 175.000 | |||||
| 2018-01-05 | 2018-01-05 | 4 | WRIGHT TIMOTHY MICHAEL | RGLS | Stock Option (Right to Buy) | D | 1,24 | 500.000 | 500.000 | |||||
| 2018-01-05 | 2018-01-05 | 4 | Hagan Joseph P | RGLS | Stock Option (Right to Buy) | D | 1,24 | 1.000.000 | 1.000.000 | |||||
| 2017-12-06 | 2017-12-04 | 4 | Witz Pascale | RGLS | Common Stock | D | 0,8900 | 60.674 | 54 | 60.674 | ||||
| 2017-12-06 | 2017-12-04 | 4 | Rosen Hugh | RGLS | Common Stock | D | 0,8900 | 56.179 | 50 | 56.179 | ||||
| 2017-12-06 | 2017-12-04 | 4 | PAPADOPOULOS STELIOS | RGLS | Common Stock | D | 0,8900 | 96.629 | 86 | 1.797.306 | ||||
| 2017-12-06 | 2017-12-04 | 4 | FOLETTA MARK G | RGLS | Common Stock | D | 0,8900 | 71.910 | 64 | 81.910 | ||||
| 2017-12-06 | 2017-12-04 | 4 | BALTIMORE DAVID | RGLS | Common Stock | D | 0,8900 | 60.674 | 54 | 60.674 | ||||
| 2017-12-06 | 2017-12-04 | 4 | RASTETTER WILLIAM H WILLIAM H RASTETTER TTEE INVESTMENT 2002 TRUST U/A DTD 11/11/2002 | RGLS | Common Stock | I | 0,8900 | 69.662 | 62 | 694.387 | ||||
| 2017-12-05 | 2017-12-04 | 4 | WRIGHT TIMOTHY MICHAEL | RGLS | Stock Option (Right to Buy) | D | 3,30 | 100.000 | 100.000 | |||||
| 2017-11-27 | 3 | BVF PARTNERS L P/IL | RGLS | Common Stock, $0.001 par value per share | D | 17.248.837 | ||||||||
| 2017-11-27 | 3 | BVF PARTNERS L P/IL | RGLS | Common Stock, $0.001 par value per share | D | 17.248.837 | ||||||||
| 2017-11-27 | 3 | BVF PARTNERS L P/IL | RGLS | Common Stock, $0.001 par value per share | D | 15.027.176 | ||||||||
| 2017-11-27 | 3 | BVF PARTNERS L P/IL | RGLS | Common Stock, $0.001 par value per share | D | 12.158.047 | ||||||||
| 2017-11-27 | 3 | BVF PARTNERS L P/IL | RGLS | Common Stock, $0.001 par value per share | D | 17.248.837 | ||||||||
| 2017-11-27 | 3 | BVF PARTNERS L P/IL | RGLS | Common Stock, $0.001 par value per share | D | 15.027.176 | ||||||||
| 2017-11-27 | 3 | BVF PARTNERS L P/IL | RGLS | Common Stock, $0.001 par value per share | D | 12.158.047 | ||||||||
| 2017-11-27 | 3 | BVF PARTNERS L P/IL | RGLS | Common Stock, $0.001 par value per share | D | 17.248.837 | ||||||||
| 2017-11-27 | 3 | BVF PARTNERS L P/IL | RGLS | Common Stock, $0.001 par value per share | D | 15.027.176 | ||||||||
| 2017-11-27 | 3 | BVF PARTNERS L P/IL | RGLS | Common Stock, $0.001 par value per share | D | 12.158.047 | ||||||||
| 2017-11-27 | 3 | BVF PARTNERS L P/IL | RGLS | Common Stock, $0.001 par value per share | D | 17.248.837 | ||||||||
| 2017-11-27 | 3 | BVF PARTNERS L P/IL | RGLS | Common Stock, $0.001 par value per share | D | 15.027.176 | ||||||||
| 2017-11-27 | 3 | BVF PARTNERS L P/IL | RGLS | Common Stock, $0.001 par value per share | D | 12.158.047 | ||||||||
| 2017-11-27 | 3 | BVF PARTNERS L P/IL | RGLS | Common Stock, $0.001 par value per share | D | 15.027.176 | ||||||||
| 2017-11-27 | 3 | BVF PARTNERS L P/IL | RGLS | Common Stock, $0.001 par value per share | D | 12.158.047 | ||||||||
| 2017-11-27 | 3 | BVF PARTNERS L P/IL | RGLS | Common Stock, $0.001 par value per share | D | 17.248.837 | ||||||||
| 2017-11-27 | 3 | BVF PARTNERS L P/IL | RGLS | Common Stock, $0.001 par value per share | D | 15.027.176 | ||||||||
| 2017-11-27 | 3 | BVF PARTNERS L P/IL | RGLS | Common Stock, $0.001 par value per share | D | 12.158.047 | ||||||||
| 2017-11-27 | 3 | BVF PARTNERS L P/IL | RGLS | Common Stock, $0.001 par value per share | D | 17.248.837 | ||||||||
| 2017-11-27 | 3 | BVF PARTNERS L P/IL | RGLS | Common Stock, $0.001 par value per share | D | 15.027.176 | ||||||||
| 2017-11-27 | 3 | BVF PARTNERS L P/IL | RGLS | Common Stock, $0.001 par value per share | D | 12.158.047 | ||||||||
| 2017-11-27 | 3 | BVF PARTNERS L P/IL | RGLS | Common Stock, $0.001 par value per share | D | 17.248.837 | ||||||||
| 2017-11-27 | 3 | BVF PARTNERS L P/IL | RGLS | Common Stock, $0.001 par value per share | D | 15.027.176 | ||||||||
| 2017-11-27 | 3 | BVF PARTNERS L P/IL | RGLS | Common Stock, $0.001 par value per share | D | 12.158.047 | ||||||||
| 2017-07-31 | 3 | Growth Equity Opportunities V, LLC | RGLS | Common Stock | D | 21.978.020 | ||||||||
| 2017-07-31 | 3 | Growth Equity Opportunities V, LLC | RGLS | Common Stock | D | 21.978.020 | ||||||||
| 2017-07-31 | 3 | Growth Equity Opportunities V, LLC | RGLS | Common Stock | D | 21.978.020 | ||||||||
| 2017-07-31 | 3 | Growth Equity Opportunities V, LLC | RGLS | Common Stock | D | 21.978.020 | ||||||||
| 2017-07-31 | 3 | Growth Equity Opportunities V, LLC | RGLS | Common Stock | D | 21.978.020 | ||||||||
| 2017-07-31 | 3 | Sonsini Peter W. See Note 1 | RGLS | Common Stock | I | 21.978.020 | ||||||||
| 2017-07-31 | 3 | Sonsini Peter W. See Note 1 | RGLS | Common Stock | I | 21.978.020 | ||||||||
| 2017-07-31 | 3 | Viswanathan Ravi See Note 1 | RGLS | Common Stock | I | 21.978.020 | ||||||||
| 2017-07-31 | 3 | Viswanathan Ravi See Note 1 | RGLS | Common Stock | I | 21.978.020 | ||||||||
| 2017-07-31 | 3 | SANDELL SCOTT D See Note 1 | RGLS | Common Stock | I | 21.978.020 | ||||||||
| 2017-07-31 | 3 | SANDELL SCOTT D See Note 1 | RGLS | Common Stock | I | 21.978.020 | ||||||||
| 2017-07-31 | 3 | MOTT DAVID M See Note 1 | RGLS | Common Stock | I | 21.978.020 | ||||||||
| 2017-07-31 | 3 | MOTT DAVID M See Note 1 | RGLS | Common Stock | I | 21.978.020 | ||||||||
| 2017-07-31 | 3 | Puttagunta Chetan See Note 1 | RGLS | Common Stock | I | 21.978.020 | ||||||||
| 2017-07-31 | 3 | Puttagunta Chetan See Note 1 | RGLS | Common Stock | I | 21.978.020 | ||||||||
| 2017-07-31 | 3 | Sakoda Jon See Note 1 | RGLS | Common Stock | I | 21.978.020 | ||||||||
| 2017-07-31 | 3 | Sakoda Jon See Note 1 | RGLS | Common Stock | I | 21.978.020 | ||||||||
| 2017-07-31 | 3 | BASKETT FOREST See Note 1 | RGLS | Common Stock | I | 21.978.020 | ||||||||
| 2017-07-31 | 3 | BASKETT FOREST See Note 1 | RGLS | Common Stock | I | 21.978.020 | ||||||||
| 2017-07-31 | 3 | Florence Anthony A. Jr. See Note 1 | RGLS | Common Stock | I | 21.978.020 | ||||||||
| 2017-07-31 | 3 | Florence Anthony A. Jr. See Note 1 | RGLS | Common Stock | I | 21.978.020 | ||||||||
| 2017-07-31 | 3 | BARRIS PETER J See Note 1 | RGLS | Common Stock | I | 21.978.020 | ||||||||
| 2017-07-31 | 3 | BARRIS PETER J See Note 1 | RGLS | Common Stock | I | 21.978.020 | ||||||||
| 2017-07-31 | 3 | Makhzoumi Mohamad See Note 1 | RGLS | Common Stock | I | 21.978.020 | ||||||||
| 2017-07-31 | 3 | Makhzoumi Mohamad See Note 1 | RGLS | Common Stock | I | 21.978.020 | ||||||||
| 2017-07-31 | 3 | MAKOWER JOSHUA See Note 1 | RGLS | Common Stock | I | 21.978.020 | ||||||||
| 2017-07-31 | 3 | MAKOWER JOSHUA See Note 1 | RGLS | Common Stock | I | 21.978.020 | ||||||||
| 2017-07-25 | 2017-07-25 | 4 | RASTETTER WILLIAM H WILLIAM H RASTETTER TTEE INVESTMENT 2002 TRUST U/A DTD 11/11/2002 | RGLS | Common Stock | I | 0,9100 | 274.725 | 250 | 624.625 | ||||
| 2017-07-25 | 2017-07-25 | 4 | WRIGHT TIMOTHY MICHAEL | RGLS | Common Stock | D | 0,9100 | 274.725 | 250 | 274.725 | ||||
| 2017-07-25 | 2017-07-25 | 4 | PAPADOPOULOS STELIOS | RGLS | Common Stock | D | 0,9100 | 1.000.000 | 910 | 1.770.677 | ||||
| 2017-07-25 | 2017-07-25 | 4 | Chevallard Daniel R. | RGLS | Common Stock | D | 0,9100 | 54.945 | 50 | 59.415 | ||||
| 2017-07-25 | 2017-07-25 | 4 | Hagan Joseph P | RGLS | Common Stock | D | 0,9100 | 219.780 | 200 | 241.297 | ||||
| 2017-06-23 | 2017-06-22 | 4 | Deeg Mark Albert | RGLS | Stock Option (Right to Buy) | D | 0,99 | 100.000 | 100.000 | |||||
| 2017-06-02 | 2017-06-01 | 4 | Witz Pascale | RGLS | Stock Option (Right to Buy) | D | 1,45 | 60.000 | 60.000 | |||||
| 2017-06-02 | 2017-06-01 | 4 | BALTIMORE DAVID | RGLS | Common Stock (Option to Buy) | D | 1,45 | 30.000 | 30.000 | |||||
| 2017-06-02 | 2017-06-01 | 4 | FOLETTA MARK G | RGLS | Stock Option (Right to Buy) | D | 1,45 | 30.000 | 30.000 | |||||
| 2017-06-02 | 2017-06-01 | 4 | PAPADOPOULOS STELIOS | RGLS | Stock Option (Right to Buy) | D | 1,45 | 30.000 | 30.000 | |||||
| 2017-06-02 | 2017-06-01 | 4 | RASTETTER WILLIAM H | RGLS | Stock Option (Right to Buy) | D | 1,45 | 30.000 | 30.000 | |||||
| 2017-06-02 | 2017-06-01 | 4 | Rosen Hugh | RGLS | Stock Option (Right to Buy) | D | 1,45 | 30.000 | 30.000 | |||||
| 2017-05-12 | 2017-05-10 | 4 | Chevallard Daniel R. | RGLS | Stock Option (Right to Buy) | D | 1,65 | 100.000 | 100.000 | |||||
| 2017-05-10 | 3 | Chevallard Daniel R. | RGLS | Common Stock | D | 8.940 | ||||||||
| 2017-05-10 | 3 | Chevallard Daniel R. | RGLS | Common Stock | D | 8.940 | ||||||||
| 2017-05-08 | 2017-05-04 | 4 | Hagan Joseph P | RGLS | Stock Option (Right to Buy) | D | 1,70 | 750.000 | 750.000 | |||||
| 2017-05-08 | 2017-05-04 | 4 | WRIGHT TIMOTHY MICHAEL | RGLS | Stock Option (Right to Buy) | D | 1,70 | 350.000 | 350.000 | |||||
| 2017-03-23 | 2017-03-22 | 4 | PAPADOPOULOS STELIOS | RGLS | Common Stock | D | 1,2270 | 300.000 | 368 | 700.677 | ||||
| 2017-03-23 | 2017-03-21 | 4 | PAPADOPOULOS STELIOS | RGLS | Common Stock | D | 1,1990 | 200.000 | 240 | 400.677 | ||||
| 2017-03-07 | 2017-03-07 | 4 | RASTETTER WILLIAM H WILLIAM H RASTETTER TTEE INVESTMENT TRUST 2002 TRUST BOARDS U/A DATED 11/11/2002 | RGLS | Common Stock | I | 1,1500 | 250.000 | 288 | 350.000 | ||||
| 2017-02-23 | 2017-02-15 | 4 | Hagan Joseph P | RGLS | Stock Option (Right to Buy) | D | 1,20 | 160.000 | 160.000 | |||||
| 2017-02-23 | 2017-02-15 | 4 | GRINT PAUL C | RGLS | Stock Option (Right to Buy) | D | 1,20 | 410.000 | 410.000 | |||||
| 2017-02-23 | 2017-02-15 | 4 | WRIGHT TIMOTHY MICHAEL | RGLS | Stock Option (Right to Buy) | D | 1,20 | 32.412 | 32.412 | |||||
| 2017-02-01 | 2017-01-30 | 4 | GRINT PAUL C | RGLS | Stock Option (Right to Buy) | D | 6,35 | 130.000 | 130.000 | |||||
| 2017-02-01 | 2017-01-30 | 4 | Hagan Joseph P | RGLS | Stock Option (Right to Buy) | D | 5,77 | 30.000 | 30.000 | |||||
| 2016-10-07 | 2016-10-05 | 4 | GRINT PAUL C | RGLS | Stock Option (Right to Buy) | D | 3,52 | 186.640 | 186.640 | |||||
| 2016-10-07 | 2016-10-05 | 4 | Hagan Joseph P | RGLS | Stock Option (Right to Buy) | D | 3,52 | 59.625 | 59.625 | |||||
| 2016-10-05 | 2016-10-03 | 4 | WRIGHT TIMOTHY MICHAEL | RGLS | Stock Option (Right to Buy) | D | 3,30 | 450.000 | 450.000 | |||||
| 2016-06-03 | 2016-06-02 | 4 | BALTIMORE DAVID | RGLS | Stock Option (Right to Buy) | D | 6,20 | 36.620 | 36.620 | |||||
| 2016-06-03 | 2016-06-02 | 4 | FOLETTA MARK G | RGLS | Stock Option (Right to Buy) | D | 6,20 | 36.620 | 36.620 | |||||
| 2016-06-03 | 2016-06-02 | 4 | PAPADOPOULOS STELIOS | RGLS | Stock Option (Right to Buy) | D | 6,20 | 36.620 | 36.620 | |||||
| 2016-06-03 | 2016-06-02 | 4 | RASTETTER WILLIAM H | RGLS | Stock Option (Right to Buy) | D | 6,20 | 36.620 | 36.620 | |||||
| 2016-06-03 | 2016-06-02 | 4 | WILLIAMS DOUGLAS E | RGLS | Stock Option (Right to Buy) | D | 6,20 | 36.620 | 36.620 | |||||
| 2016-06-03 | 2016-06-02 | 4 | Rosen Hugh | RGLS | Stock Option (Right to Buy) | D | 6,20 | 70.952 | 70.952 | |||||
| 2016-03-07 | 2016-03-03 | 4 | Hagan Joseph P | RGLS | Common Stock | D | 7,1900 | 10.000 | 72 | 10.000 | ||||
| 2016-02-24 | 2016-02-23 | 4 | ALNYLAM PHARMACEUTICALS, INC. | RGLS | Common Stock | D | 7,1800 | -1.000.000 | -7.180 | 4.896.716 | ||||
| 2016-02-05 | 2016-02-04 | 4 | GRINT PAUL C | RGLS | Stock Option (Right to Buy) | D | 6,35 | 265.000 | 265.000 | |||||
| 2016-01-06 | 2016-01-04 | 4 | Hagan Joseph P | RGLS | Stock Option (Right to Buy) | D | 8,57 | 420.000 | 420.000 | |||||
| 2016-01-06 | 2015-12-16 | 4 | GRINT PAUL C | RGLS | Stock Option (Right to Buy) | D | 7,58 | 30.000 | 30.000 | |||||
| 2015-08-13 | 2015-08-13 | 4 | FOLETTA MARK G | RGLS | Common Stock | D | 7,6405 | 10.000 | 76 | 10.000 | ||||
| 2015-08-07 | 2015-08-07 | 4 | PAPADOPOULOS STELIOS | RGLS | Stock Option (Right to Buy) | D | 2,66 | -15.677 | 1.823 | |||||
| 2015-08-07 | 2015-08-07 | 4 | PAPADOPOULOS STELIOS | RGLS | Stock Option (Right to Buy) | D | 1,74 | -17.500 | 0 | |||||
| 2015-08-07 | 2015-08-07 | 4 | PAPADOPOULOS STELIOS | RGLS | Stock Option (Right to Buy) | D | 0,38 | -17.500 | 0 | |||||
| 2015-08-07 | 2015-08-07 | 4 | PAPADOPOULOS STELIOS | RGLS | Common Stock | D | 2,6600 | 15.677 | 42 | 200.677 | ||||
| 2015-08-07 | 2015-08-07 | 4 | PAPADOPOULOS STELIOS | RGLS | Common Stock | D | 1,7400 | 17.500 | 30 | 185.000 | ||||
| 2015-08-07 | 2015-08-07 | 4 | PAPADOPOULOS STELIOS | RGLS | Common Stock | D | 0,3800 | 17.500 | 7 | 167.500 | ||||
| 2015-07-21 | 2015-07-21 | 4 | RASTETTER WILLIAM H William H. Rastetter TTEE Investment 2002 Trust Boards U/A dated 11/11/2002 | RGLS | Common Stock | I | 10,1935 | 61.235 | 624 | 100.000 | ||||
| 2015-07-21 | 2015-07-20 | 4 | RASTETTER WILLIAM H William H. Rastetter TTEE Investment 2002 Trust Boards U/A dated 11/11/2002 | RGLS | Common Stock | I | 10,1323 | 38.765 | 393 | 38.765 | ||||
| 2015-07-17 | 2015-07-17 | 4 | ISIS PHARMACEUTICALS INC | RGLS | Common Stock | D | 10,2140 | -111.000 | -1.134 | 5.173.172 | ||||
| 2015-07-17 | 2015-07-16 | 4 | ISIS PHARMACEUTICALS INC | RGLS | Common Stock | D | 10,7866 | -167.000 | -1.801 | 5.284.172 | ||||
| 2015-07-17 | 2015-07-15 | 4 | ISIS PHARMACEUTICALS INC | RGLS | Common Stock | D | 10,7620 | -65.133 | -701 | 5.451.172 | ||||
| 2015-07-02 | 2015-06-30 | 4 | ISIS PHARMACEUTICALS INC | RGLS | Common Stock | D | 10,7948 | -13.248 | -143 | 5.516.305 | ||||
| 2015-07-02 | 2015-06-23 | 4 | ISIS PHARMACEUTICALS INC | RGLS | Common Stock | D | 13.248 | 5.529.553 | ||||||
| 2015-06-26 | 2015-06-10 | 4 | WILLIAMS DOUGLAS E | RGLS | Stock Option (Right to Buy) | D | 10,02 | 17.500 | 17.500 | |||||
| 2015-06-26 | 2015-06-10 | 4 | CARTER BRUCE L A | RGLS | Stock Option (Right to Buy) | D | 10,02 | 17.500 | 17.500 | |||||
| 2015-06-26 | 2015-06-10 | 4 | BALTIMORE DAVID | RGLS | Stock Option (Right to Buy) | D | 10,02 | 17.500 | 17.500 | |||||
| 2015-06-26 | 2015-06-10 | 4 | CARTER BRUCE L A | RGLS | Stock Option (Right to Buy) | D | 10,02 | 17.500 | 17.500 | |||||
| 2015-06-26 | 2015-06-10 | 4 | RASTETTER WILLIAM H | RGLS | Stock Option (Right to Buy) | D | 10,02 | 17.500 | 17.500 | |||||
| 2015-06-26 | 2015-06-10 | 4 | FOLETTA MARK G | RGLS | Stock Option (Right to Buy) | D | 10,02 | 17.500 | 17.500 | |||||
| 2015-06-26 | 2015-06-10 | 4 | PAPADOPOULOS STELIOS | RGLS | Stock Option (Right to Buy) | D | 10,02 | 17.500 | 17.500 | |||||
| 2015-06-26 | 2015-06-25 | 4 | GRINT PAUL C | RGLS | Stock Option (Right to Buy) | D | 10,22 | 500.000 | 500.000 | |||||
| 2015-04-21 | 2015-04-21 | 4 | XANTHOPOULOS KLEANTHIS G | RGLS | Stock Option (Right to Buy) | D | 0,38 | -60.000 | 8.287 | |||||
| 2015-04-21 | 2015-04-21 | 4 | XANTHOPOULOS KLEANTHIS G | RGLS | Common Stock | D | 17,7330 | -60.000 | -1.064 | 3.705 | ||||
| 2015-04-21 | 2015-04-21 | 4 | XANTHOPOULOS KLEANTHIS G | RGLS | Common Stock | D | 0,3800 | 60.000 | 23 | 63.705 | ||||
| 2015-04-21 | 2015-04-20 | 4 | XANTHOPOULOS KLEANTHIS G | RGLS | Stock Option (Right to Buy) | D | 0,38 | -66.071 | 68.287 | |||||
| 2015-04-21 | 2015-04-20 | 4 | XANTHOPOULOS KLEANTHIS G | RGLS | Common Stock | D | 16,8533 | -66.071 | -1.114 | 3.705 | ||||
| 2015-04-21 | 2015-04-20 | 4 | XANTHOPOULOS KLEANTHIS G | RGLS | Common Stock | D | 0,3800 | 66.071 | 25 | 69.776 | ||||
| 2015-04-21 | 2015-04-17 | 4 | XANTHOPOULOS KLEANTHIS G | RGLS | Stock Option (Right to Buy) | D | 0,38 | -73.929 | 134.358 | |||||
| 2015-04-21 | 2015-04-17 | 4 | XANTHOPOULOS KLEANTHIS G | RGLS | Common Stock | D | 16,9352 | -73.929 | -1.252 | 3.705 | ||||
| 2015-04-21 | 2015-04-17 | 4 | XANTHOPOULOS KLEANTHIS G | RGLS | Common Stock | D | 0,3800 | 73.929 | 28 | 77.634 | ||||
| 2015-04-14 | 2015-04-13 | 4 | CARTER BRUCE L A | RGLS | Stock Option (Right to Buy) | D | 4,78 | -20.000 | 10.000 | |||||
| 2015-04-14 | 2015-04-13 | 4 | CARTER BRUCE L A | RGLS | Common Stock | D | 17,6582 | -20.000 | -353 | 0 | ||||
| 2015-04-14 | 2015-04-13 | 4 | CARTER BRUCE L A | RGLS | Common Stock | D | 4,7800 | 20.000 | 96 | 20.000 | ||||
| 2015-03-05 | 2015-03-05 | 4 | XANTHOPOULOS KLEANTHIS G | RGLS | Stock Option (Right to Buy) | D | 0,38 | -89.230 | 208.287 | |||||
| 2015-03-05 | 2015-03-05 | 4 | XANTHOPOULOS KLEANTHIS G | RGLS | Common Stock | D | 20,8143 | -23.616 | -492 | 2.466 | ||||
| 2015-03-05 | 2015-03-05 | 4 | XANTHOPOULOS KLEANTHIS G | RGLS | Common Stock | D | 20,0645 | -65.614 | -1.317 | 26.082 | ||||
| 2015-03-05 | 2015-03-05 | 4 | XANTHOPOULOS KLEANTHIS G | RGLS | Common Stock | D | 0,3800 | 89.230 | 34 | 91.696 | ||||
| 2015-03-03 | 2015-02-27 | 4 | XANTHOPOULOS KLEANTHIS G | RGLS | Stock Option (Right to Buy) | D | 0,38 | -70 | 297.517 | |||||
| 2015-03-03 | 2015-02-27 | 4 | XANTHOPOULOS KLEANTHIS G | RGLS | Common Stock | D | 19,5000 | -70 | -1 | 2.466 | ||||
| 2015-03-03 | 2015-02-27 | 4 | XANTHOPOULOS KLEANTHIS G | RGLS | Common Stock | D | 0,3800 | 70 | 0 | 2.536 | ||||
| 2015-02-03 | 2015-02-02 | 4 | XANTHOPOULOS KLEANTHIS G | RGLS | Stock Option (Right to Buy) | D | 0,38 | -2.400 | 297.587 | |||||
| 2015-02-03 | 2015-02-02 | 4 | XANTHOPOULOS KLEANTHIS G | RGLS | Common Stock | D | 19,7667 | -2.400 | -47 | 2.466 | ||||
| 2015-02-03 | 2015-02-02 | 4 | XANTHOPOULOS KLEANTHIS G | RGLS | Common Stock | D | 0,3800 | 2.400 | 1 | 4.866 | ||||
| 2015-02-03 | 2015-01-30 | 4 | XANTHOPOULOS KLEANTHIS G | RGLS | Stock Option (Right to Buy) | D | 0,38 | -3.300 | 299.987 | |||||
| 2015-02-03 | 2015-01-30 | 4 | XANTHOPOULOS KLEANTHIS G | RGLS | Common Stock | D | 19,5004 | -3.300 | -64 | 2.466 | ||||
| 2015-02-03 | 2015-01-30 | 4 | XANTHOPOULOS KLEANTHIS G | RGLS | Common Stock | D | 0,3800 | 3.300 | 1 | 5.766 | ||||
| 2015-01-30 | 2015-01-28 | 4 | Gibson Neil W | RGLS | Common Stock | D | 18,6589 | -8.655 | -161 | 0 | ||||
| 2015-01-30 | 2015-01-28 | 4 | Gibson Neil W | RGLS | Common Stock | D | 17,9804 | -71.345 | -1.283 | 8.655 | ||||
| 2015-01-30 | 2015-01-29 | 4 | XANTHOPOULOS KLEANTHIS G | RGLS | Stock Option (Right to Buy) | D | 0,38 | -60.000 | 303.287 | |||||
| 2015-01-30 | 2015-01-29 | 4 | XANTHOPOULOS KLEANTHIS G | RGLS | Common Stock | D | 18,4019 | -26.227 | -483 | 2.466 | ||||
| 2015-01-30 | 2015-01-29 | 4 | XANTHOPOULOS KLEANTHIS G | RGLS | Common Stock | D | 17,7659 | -33.773 | -600 | 28.693 | ||||
| 2015-01-30 | 2015-01-29 | 4 | XANTHOPOULOS KLEANTHIS G | RGLS | Common Stock | D | 0,3800 | 60.000 | 23 | 62.466 | ||||
| 2015-01-30 | 2015-01-28 | 4 | XANTHOPOULOS KLEANTHIS G | RGLS | Stock Option (Right to Buy) | D | 0,38 | -85.000 | 363.287 | |||||
| 2015-01-30 | 2015-01-28 | 4 | XANTHOPOULOS KLEANTHIS G | RGLS | Common Stock | D | 18,6851 | -12.989 | -243 | 2.466 | ||||
| 2015-01-30 | 2015-01-28 | 4 | XANTHOPOULOS KLEANTHIS G | RGLS | Common Stock | D | 17,9669 | -72.011 | -1.294 | 15.455 | ||||
| 2015-01-30 | 2015-01-28 | 4 | XANTHOPOULOS KLEANTHIS G | RGLS | Common Stock | D | 0,3800 | 85.000 | 32 | 87.466 | ||||
| 2014-12-15 | 2014-12-12 | 4 | PAPADOPOULOS STELIOS | RGLS | Stock Option (Right to Buy) | D | 0,38 | -150.000 | 0 | |||||
| 2014-12-15 | 2014-12-12 | 4 | PAPADOPOULOS STELIOS | RGLS | Common Stock | D | 0,3800 | 150.000 | 57 | 150.000 | ||||
| 2014-12-04 | 2014-12-02 | 4 | Szekeres David Leslie | RGLS | Stock Option (Right to Buy) | D | 17,76 | 81.101 | 81.101 | |||||
| 2014-12-04 | 2014-12-02 | 4 | Gibson Neil W | RGLS | Stock Option (Right to Buy) | D | 17,76 | 90.378 | 90.378 | |||||
| 2014-12-04 | 2014-12-02 | 4 | GRINT PAUL C | RGLS | Stock Option (Right to Buy) | D | 17,76 | 50.870 | 50.870 | |||||
| 2014-12-04 | 2014-12-02 | 4 | XANTHOPOULOS KLEANTHIS G | RGLS | Stock Option (Right to Buy) | D | 17,76 | 231.634 | 231.634 | |||||
| 2014-12-01 | 2014-11-28 | 4 | Gibson Neil W | RGLS | Stock Option (Right to Buy) | D | 1,74 | -2.500 | 111.500 | |||||
| 2014-12-01 | 2014-11-28 | 4 | Gibson Neil W | RGLS | Common Stock | D | 19,6300 | -1.500 | -29 | 80.000 | ||||
| 2014-12-01 | 2014-11-28 | 4 | Gibson Neil W | RGLS | Common Stock | D | 18,8000 | -1.000 | -19 | 81.500 | ||||
| 2014-12-01 | 2014-11-28 | 4 | Gibson Neil W | RGLS | Common Stock | D | 1,7400 | 2.500 | 4 | 82.500 | ||||
| 2014-11-14 | 2014-11-12 | 4 | ASTRAZENECA PLC | RGLS | COMMON STOCK | I | 17,0000 | -2.000.000 | -34.000 | 4.250.000 | ||||
| 2014-11-05 | 2014-11-03 | 4 | ISIS PHARMACEUTICALS INC | RGLS | Common Stock | D | 15,9375 | -1.279.411 | -20.391 | 5.516.305 | ||||
| 2014-10-31 | 2014-10-29 | 4 | Gibson Neil W | RGLS | Stock Option (Right to Buy) | D | 1,74 | -2.500 | 114.000 | |||||
| 2014-10-31 | 2014-10-29 | 4 | Gibson Neil W | RGLS | Common Stock | D | 20,4100 | -200 | -4 | 80.000 | ||||
| 2014-10-31 | 2014-10-29 | 4 | Gibson Neil W | RGLS | Common Stock | D | 19,6700 | -1.200 | -24 | 80.200 | ||||
| 2014-10-31 | 2014-10-29 | 4 | Gibson Neil W | RGLS | Common Stock | D | 18,6800 | -1.100 | -21 | 81.400 | ||||
| 2014-10-31 | 2014-10-29 | 4 | Gibson Neil W | RGLS | Common Stock | D | 1,7400 | 2.500 | 4 | 82.500 | ||||
| 2014-10-31 | 2014-10-29 | 4 | XANTHOPOULOS KLEANTHIS G | RGLS | Stock Option (Right to Buy) | D | 0,38 | -3.505 | 448.287 | |||||
| 2014-10-31 | 2014-10-29 | 4 | XANTHOPOULOS KLEANTHIS G | RGLS | Common Stock | D | 20,4100 | -100 | -2 | 2.466 | ||||
| 2014-10-31 | 2014-10-29 | 4 | XANTHOPOULOS KLEANTHIS G | RGLS | Common Stock | D | 19,7800 | -2.005 | -40 | 2.566 | ||||
| 2014-10-31 | 2014-10-29 | 4 | XANTHOPOULOS KLEANTHIS G | RGLS | Common Stock | D | 18,6600 | -1.400 | -26 | 4.571 | ||||
| 2014-10-31 | 2014-10-29 | 4 | XANTHOPOULOS KLEANTHIS G | RGLS | Common Stock | D | 0,3800 | 3.505 | 1 | 5.971 | ||||
| 2014-10-28 | 2014-10-24 | 4/A | ALNYLAM PHARMACEUTICALS, INC. | RGLS | Common Stock | D | 16,2922 | -446 | -7 | 5.896.716 | ||||
| 2014-10-28 | 2014-10-24 | 4/A | ALNYLAM PHARMACEUTICALS, INC. | RGLS | Common Stock | D | 15,5014 | -350 | -5 | 5.897.162 | ||||
| 2014-10-28 | 2014-10-24 | 4/A | ALNYLAM PHARMACEUTICALS, INC. | RGLS | Common Stock | D | 14,6277 | -1.054 | -15 | 5.897.512 | ||||
| 2014-10-28 | 2014-10-23 | 4/A | ALNYLAM PHARMACEUTICALS, INC. | RGLS | Common Stock | D | 15,4500 | -50 | -1 | 5.898.566 | ||||
| 2014-10-28 | 2014-10-23 | 4/A | ALNYLAM PHARMACEUTICALS, INC. | RGLS | Common Stock | D | 14,8956 | -450 | -7 | 5.898.616 | ||||
| 2014-10-28 | 2014-10-23 | 4/A | ALNYLAM PHARMACEUTICALS, INC. | RGLS | Common Stock | D | 13,9390 | -1.200 | -17 | 5.899.066 | ||||
| 2014-10-28 | 2014-10-22 | 4/A | ALNYLAM PHARMACEUTICALS, INC. | RGLS | Common Stock | D | 17,1100 | -175 | -3 | 5.900.266 | ||||
| 2014-10-28 | 2014-10-22 | 4/A | ALNYLAM PHARMACEUTICALS, INC. | RGLS | Common Stock | D | 16,5881 | -11.376 | -189 | 5.900.441 | ||||
| 2014-10-28 | 2014-10-22 | 4/A | ALNYLAM PHARMACEUTICALS, INC. | RGLS | Common Stock | D | 14,6707 | -15.156 | -222 | 5.911.817 | ||||
| 2014-10-28 | 2014-10-22 | 4/A | ALNYLAM PHARMACEUTICALS, INC. | RGLS | Common Stock | D | 13,9112 | -57.753 | -803 | 5.926.973 | ||||
| 2014-10-28 | 2014-10-22 | 4/A | ALNYLAM PHARMACEUTICALS, INC. | RGLS | Common Stock | D | 12,8309 | -15.791 | -203 | 5.984.726 | ||||
| 2014-10-28 | 2014-10-22 | 4/A | ALNYLAM PHARMACEUTICALS, INC. | RGLS | Common Stock | D | 12,1792 | -9.283 | -113 | 6.000.517 | ||||
| 2014-10-28 | 2014-10-24 | 4/A | ISIS PHARMACEUTICALS INC | RGLS | Common Stock | D | 16,2922 | -446 | -7 | 6.795.716 | ||||
| 2014-10-28 | 2014-10-24 | 4/A | ISIS PHARMACEUTICALS INC | RGLS | Common Stock | D | 15,5014 | -350 | -5 | 6.796.162 | ||||
| 2014-10-28 | 2014-10-24 | 4/A | ISIS PHARMACEUTICALS INC | RGLS | Common Stock | D | 14,6277 | -1.054 | -15 | 6.796.512 | ||||
| 2014-10-28 | 2014-10-23 | 4/A | ISIS PHARMACEUTICALS INC | RGLS | Common Stock | D | 15,4500 | -50 | -1 | 6.797.566 | ||||
| 2014-10-28 | 2014-10-23 | 4/A | ISIS PHARMACEUTICALS INC | RGLS | Common Stock | D | 14,8956 | -450 | -7 | 6.797.616 | ||||
| 2014-10-28 | 2014-10-23 | 4/A | ISIS PHARMACEUTICALS INC | RGLS | Common Stock | D | 13,9390 | -1.200 | -17 | 6.798.066 | ||||
| 2014-10-28 | 2014-10-22 | 4/A | ISIS PHARMACEUTICALS INC | RGLS | Common Stock | D | 17,1100 | -175 | -3 | 6.799.266 | ||||
| 2014-10-28 | 2014-10-22 | 4/A | ISIS PHARMACEUTICALS INC | RGLS | Common Stock | D | 16,5881 | -11.376 | -189 | 6.799.441 | ||||
| 2014-10-28 | 2014-10-22 | 4/A | ISIS PHARMACEUTICALS INC | RGLS | Common Stock | D | 14,6707 | -15.156 | -222 | 6.810.817 | ||||
| 2014-10-28 | 2014-10-22 | 4/A | ISIS PHARMACEUTICALS INC | RGLS | Common Stock | D | 13,9112 | -57.753 | -803 | 6.825.973 | ||||
| 2014-10-28 | 2014-10-22 | 4/A | ISIS PHARMACEUTICALS INC | RGLS | Common Stock | D | 12,8309 | -15.791 | -203 | 6.883.726 | ||||
| 2014-10-28 | 2014-10-22 | 4/A | ISIS PHARMACEUTICALS INC | RGLS | Common Stock | D | 12,1792 | -9.283 | -113 | 6.899.517 | ||||
| 2014-10-24 | 2014-10-24 | 4 | ISIS PHARMACEUTICALS INC | RGLS | Common Stock | D | 15,1943 | -1.850 | -28 | 6.795.716 | ||||
| 2014-10-24 | 2014-10-23 | 4 | ISIS PHARMACEUTICALS INC | RGLS | Common Stock | D | 14,2367 | -1.700 | -24 | 6.797.566 | ||||
| 2014-10-24 | 2014-10-22 | 4 | ISIS PHARMACEUTICALS INC | RGLS | Common Stock | D | 13,9968 | -109.534 | -1.533 | 6.799.266 | ||||
| 2014-10-24 | 2014-10-24 | 4 | ALNYLAM PHARMACEUTICALS, INC. | RGLS | Common Stock | D | 15,1943 | -1.850 | -28 | 5.896.716 | ||||
| 2014-10-24 | 2014-10-23 | 4 | ALNYLAM PHARMACEUTICALS, INC. | RGLS | Common Stock | D | 14,2367 | -1.700 | -24 | 5.898.566 | ||||
| 2014-10-24 | 2014-10-22 | 4 | ALNYLAM PHARMACEUTICALS, INC. | RGLS | Common Stock | D | 13,9968 | -109.534 | -1.533 | 5.900.266 | ||||
| 2014-10-24 | 2014-10-22 | 4 | Gibson Neil W | RGLS | Stock Option (Right to Buy) | D | 1,74 | -3.300 | 116.500 | |||||
| 2014-10-24 | 2014-10-22 | 4 | Gibson Neil W | RGLS | Common Stock | D | 14,4376 | -3.300 | -48 | 80.000 | ||||
| 2014-10-24 | 2014-10-22 | 4 | Gibson Neil W | RGLS | Common Stock | D | 1,7400 | 3.300 | 6 | 83.300 | ||||
| 2014-10-22 | 2014-10-20 | 4 | Gibson Neil W | RGLS | Stock Option (Right to Buy) | D | 6,13 | 40.000 | 40.000 | |||||
| 2014-10-22 | 2014-10-20 | 4 | Szekeres David Leslie | RGLS | Stock Option (Right to Buy) | D | 8,51 | 40.000 | 40.000 | |||||
| 2014-10-22 | 2014-10-20 | 4 | XANTHOPOULOS KLEANTHIS G | RGLS | Stock Option (Right to Buy) | D | 6,13 | 88.000 | 88.000 | |||||
| 2014-10-22 | 2014-10-20 | 4 | GRINT PAUL C | RGLS | Stock Option (Right to Buy) | D | 7,58 | 40.000 | 40.000 | |||||
| 2014-10-21 | 2014-10-20 | 4 | XANTHOPOULOS KLEANTHIS G | RGLS | Stock Option (Right to Buy) | D | 0,38 | -300 | 451.792 | |||||
| 2014-10-21 | 2014-10-20 | 4 | XANTHOPOULOS KLEANTHIS G | RGLS | Common Stock | D | 7,0000 | -300 | -2 | 2.466 | ||||
| 2014-10-21 | 2014-10-20 | 4 | XANTHOPOULOS KLEANTHIS G | RGLS | Common Stock | D | 0,3800 | 300 | 0 | 2.766 | ||||
| 2014-10-21 | 2014-10-17 | 4 | XANTHOPOULOS KLEANTHIS G | RGLS | Stock Option (Right to Buy) | D | 0,38 | -400 | 452.092 | |||||
| 2014-10-21 | 2014-10-17 | 4 | XANTHOPOULOS KLEANTHIS G | RGLS | Common Stock | D | 7,0400 | -400 | -3 | 2.466 | ||||
| 2014-10-21 | 2014-10-17 | 4 | XANTHOPOULOS KLEANTHIS G | RGLS | Common Stock | D | 0,3800 | 400 | 0 | 2.866 | ||||
| 2014-10-17 | 2014-10-17 | 4 | ALNYLAM PHARMACEUTICALS, INC. | RGLS | Common Stock | D | 6,7903 | -3.000 | -20 | 6.009.800 | ||||
| 2014-10-17 | 2014-10-16 | 4 | ALNYLAM PHARMACEUTICALS, INC. | RGLS | Common Stock | D | 6,7605 | -4.800 | -32 | 6.012.800 | ||||
| 2014-10-17 | 2014-10-15 | 4 | ALNYLAM PHARMACEUTICALS, INC. | RGLS | Common Stock | D | 6,6714 | -4.300 | -29 | 6.017.600 | ||||
| 2014-10-17 | 2014-10-17 | 4 | ISIS PHARMACEUTICALS INC | RGLS | Common Stock | D | 6,7903 | -3.000 | -20 | 6.908.800 | ||||
| 2014-10-17 | 2014-10-16 | 4 | ISIS PHARMACEUTICALS INC | RGLS | Common Stock | D | 6,7605 | -4.800 | -32 | 6.911.800 | ||||
| 2014-10-17 | 2014-10-15 | 4 | ISIS PHARMACEUTICALS INC | RGLS | Common Stock | D | 6,6714 | -4.300 | -29 | 6.916.600 | ||||
| 2014-10-14 | 2014-10-14 | 4 | XANTHOPOULOS KLEANTHIS G | RGLS | Stock Option (Right to Buy) | D | 0,38 | -400 | 452.492 | |||||
| 2014-10-14 | 2014-10-14 | 4 | XANTHOPOULOS KLEANTHIS G | RGLS | Common Stock | D | 7,0000 | -400 | -3 | 2.466 | ||||
| 2014-10-14 | 2014-10-14 | 4 | XANTHOPOULOS KLEANTHIS G | RGLS | Common Stock | D | 0,3800 | 400 | 0 | 2.866 | ||||
| 2014-10-14 | 2014-10-09 | 4 | XANTHOPOULOS KLEANTHIS G | RGLS | Stock Option (Right to Buy) | D | 0,38 | -105 | 452.892 | |||||
| 2014-10-14 | 2014-10-09 | 4 | XANTHOPOULOS KLEANTHIS G | RGLS | Common Stock | D | 7,0000 | -105 | -1 | 2.466 | ||||
| 2014-10-14 | 2014-10-09 | 4 | XANTHOPOULOS KLEANTHIS G | RGLS | Common Stock | D | 0,3800 | 105 | 0 | 2.571 | ||||
| 2014-10-10 | 2014-10-10 | 4 | ALNYLAM PHARMACEUTICALS, INC. | RGLS | Common Stock | D | 6,4063 | -2.000 | -13 | 6.021.900 | ||||
| 2014-10-10 | 2014-10-09 | 4 | ALNYLAM PHARMACEUTICALS, INC. | RGLS | Common Stock | D | 6,5764 | -4.750 | -31 | 6.023.900 | ||||
| 2014-10-10 | 2014-10-08 | 4 | ALNYLAM PHARMACEUTICALS, INC. | RGLS | Common Stock | D | 6,6326 | -3.300 | -22 | 6.028.650 | ||||
| 2014-10-10 | 2014-10-10 | 4 | ISIS PHARMACEUTICALS INC | RGLS | Common Stock | D | 6,4063 | -2.000 | -13 | 6.920.900 | ||||
| 2014-10-10 | 2014-10-09 | 4 | ISIS PHARMACEUTICALS INC | RGLS | Common Stock | D | 6,5764 | -4.750 | -31 | 6.922.900 | ||||
| 2014-10-10 | 2014-10-08 | 4 | ISIS PHARMACEUTICALS INC | RGLS | Common Stock | D | 6,6326 | -3.300 | -22 | 6.927.650 | ||||
| 2014-10-03 | 2014-10-03 | 4 | ALNYLAM PHARMACEUTICALS, INC. | RGLS | Common Stock | D | 6,8751 | -3.300 | -23 | 6.031.950 | ||||
| 2014-10-03 | 2014-10-02 | 4 | ALNYLAM PHARMACEUTICALS, INC. | RGLS | Common Stock | D | 6,6407 | -3.750 | -25 | 6.035.250 | ||||
| 2014-10-03 | 2014-10-01 | 4 | ALNYLAM PHARMACEUTICALS, INC. | RGLS | Common Stock | D | 6,7103 | -3.250 | -22 | 6.039.000 | ||||
| 2014-10-03 | 2014-10-03 | 4 | ISIS PHARMACEUTICALS INC | RGLS | Common Stock | D | 6,8751 | -3.300 | -23 | 6.930.950 | ||||
| 2014-10-03 | 2014-10-02 | 4 | ISIS PHARMACEUTICALS INC | RGLS | Common Stock | D | 6,6407 | -3.750 | -25 | 6.934.250 | ||||
| 2014-10-03 | 2014-10-01 | 4 | ISIS PHARMACEUTICALS INC | RGLS | Common Stock | D | 6,7103 | -3.250 | -22 | 6.938.000 | ||||
| 2014-10-02 | 2014-09-30 | 4 | XANTHOPOULOS KLEANTHIS G | RGLS | Stock Option (Right to Buy) | D | 0,38 | -2.300 | 452.997 | |||||
| 2014-10-02 | 2014-09-30 | 4 | XANTHOPOULOS KLEANTHIS G | RGLS | Common Stock | D | 7,0163 | -2.300 | -16 | 2.466 | ||||
| 2014-10-02 | 2014-09-30 | 4 | XANTHOPOULOS KLEANTHIS G | RGLS | Common Stock | D | 0,3800 | 2.300 | 1 | 4.766 | ||||
| 2014-09-26 | 2014-09-26 | 4 | ALNYLAM PHARMACEUTICALS, INC. | RGLS | Common Stock | D | 7,0393 | -2.500 | -18 | 6.042.250 | ||||
| 2014-09-26 | 2014-09-25 | 4 | ALNYLAM PHARMACEUTICALS, INC. | RGLS | Common Stock | D | 7,1160 | -2.500 | -18 | 6.044.750 | ||||
| 2014-09-26 | 2014-09-24 | 4 | ALNYLAM PHARMACEUTICALS, INC. | RGLS | Common Stock | D | 7,1942 | -3.750 | -27 | 6.047.250 | ||||
| 2014-09-26 | 2014-09-26 | 4 | ISIS PHARMACEUTICALS INC | RGLS | Common Stock | D | 7,0393 | -2.500 | -18 | 6.941.250 | ||||
| 2014-09-26 | 2014-09-25 | 4 | ISIS PHARMACEUTICALS INC | RGLS | Common Stock | D | 7,1160 | -2.500 | -18 | 6.943.750 | ||||
| 2014-09-26 | 2014-09-24 | 4 | ISIS PHARMACEUTICALS INC | RGLS | Common Stock | D | 7,1942 | -3.750 | -27 | 6.946.250 | ||||
| 2014-09-19 | 2014-09-19 | 4 | ALNYLAM PHARMACEUTICALS, INC. | RGLS | Common Stock | D | 7,2163 | -4.100 | -30 | 6.051.000 | ||||
| 2014-09-19 | 2014-09-18 | 4 | ALNYLAM PHARMACEUTICALS, INC. | RGLS | Common Stock | D | 7,3984 | -1.500 | -11 | 6.055.100 | ||||
| 2014-09-19 | 2014-09-17 | 4 | ALNYLAM PHARMACEUTICALS, INC. | RGLS | Common Stock | D | 7,4331 | -2.100 | -16 | 6.056.600 | ||||
| 2014-09-19 | 2014-09-19 | 4 | ISIS PHARMACEUTICALS INC | RGLS | Common Stock | D | 7,2163 | -4.100 | -30 | 6.950.000 | ||||
| 2014-09-19 | 2014-09-18 | 4 | ISIS PHARMACEUTICALS INC | RGLS | Common Stock | D | 7,3984 | -1.500 | -11 | 6.954.100 | ||||
| 2014-09-19 | 2014-09-17 | 4 | ISIS PHARMACEUTICALS INC | RGLS | Common Stock | D | 7,4331 | -2.100 | -16 | 6.955.600 | ||||
| 2014-09-15 | 2014-09-12 | 4 | Gibson Neil W | RGLS | Stock Option (Right to Buy) | D | 1,74 | -2.200 | 119.800 | |||||
| 2014-09-15 | 2014-09-12 | 4 | Gibson Neil W | RGLS | Common Stock | D | 8,0075 | -2.200 | -18 | 80.000 | ||||
| 2014-09-15 | 2014-09-12 | 4 | Gibson Neil W | RGLS | Common Stock | D | 1,7400 | 2.200 | 4 | 82.200 | ||||
| 2014-09-15 | 2014-09-11 | 4 | Gibson Neil W | RGLS | Stock Option (Right to Buy) | D | 1,74 | -2.000 | 122.000 | |||||
| 2014-09-15 | 2014-09-11 | 4 | Gibson Neil W | RGLS | Common Stock | D | 8,0050 | -2.000 | -16 | 80.000 | ||||
| 2014-09-15 | 2014-09-11 | 4 | Gibson Neil W | RGLS | Common Stock | D | 1,7400 | 2.000 | 3 | 82.000 | ||||
| 2014-09-12 | 2014-09-12 | 4 | ALNYLAM PHARMACEUTICALS, INC. | RGLS | Common Stock | D | 7,9602 | -3.500 | -28 | 6.058.700 | ||||
| 2014-09-12 | 2014-09-11 | 4 | ALNYLAM PHARMACEUTICALS, INC. | RGLS | Common Stock | D | 7,8341 | -3.400 | -27 | 6.062.200 | ||||
| 2014-09-12 | 2014-09-10 | 4 | ALNYLAM PHARMACEUTICALS, INC. | RGLS | Common Stock | D | 7,6996 | -2.000 | -15 | 6.065.600 | ||||
| 2014-09-12 | 2014-09-12 | 4 | ISIS PHARMACEUTICALS INC | RGLS | Common Stock | D | 7,9602 | -3.500 | -28 | 6.957.700 | ||||
| 2014-09-12 | 2014-09-11 | 4 | ISIS PHARMACEUTICALS INC | RGLS | Common Stock | D | 7,8341 | -3.400 | -27 | 6.961.200 | ||||
| 2014-09-12 | 2014-09-10 | 4 | ISIS PHARMACEUTICALS INC | RGLS | Common Stock | D | 7,6996 | -2.000 | -15 | 6.964.600 | ||||
| 2014-09-05 | 2014-09-05 | 4 | ALNYLAM PHARMACEUTICALS, INC. | RGLS | Common Stock | D | 7,0727 | -2.400 | -17 | 6.067.600 | ||||
| 2014-09-05 | 2014-09-04 | 4 | ALNYLAM PHARMACEUTICALS, INC. | RGLS | Common Stock | D | 7,1094 | -6.000 | -43 | 6.070.000 | ||||
| 2014-09-05 | 2014-09-03 | 4 | ALNYLAM PHARMACEUTICALS, INC. | RGLS | Common Stock | D | 6,9519 | -1.650 | -11 | 6.076.000 | ||||
| 2014-09-05 | 2014-09-05 | 4 | ISIS PHARMACEUTICALS INC | RGLS | Common Stock | D | 7,0727 | -2.400 | -17 | 6.966.600 | ||||
| 2014-09-05 | 2014-09-04 | 4 | ISIS PHARMACEUTICALS INC | RGLS | Common Stock | D | 7,1094 | -6.000 | -43 | 6.969.000 | ||||
| 2014-09-05 | 2014-09-03 | 4 | ISIS PHARMACEUTICALS INC | RGLS | Common Stock | D | 6,9519 | -1.650 | -11 | 6.975.000 | ||||
| 2014-08-29 | 2014-08-28 | 4 | XANTHOPOULOS KLEANTHIS G | "RGLS" | Stock Option (Right to Buy) | D | 0,38 | -3.505 | 455.297 | |||||
| 2014-08-29 | 2014-08-28 | 4 | XANTHOPOULOS KLEANTHIS G | "RGLS" | Common Stock | D | 7,0626 | -3.505 | -25 | 0 | ||||
| 2014-08-29 | 2014-08-28 | 4 | XANTHOPOULOS KLEANTHIS G | "RGLS" | Common Stock | D | 0,3800 | 3.505 | 1 | 3.505 | ||||
| 2014-08-29 | 2014-08-29 | 4 | ALNYLAM PHARMACEUTICALS, INC. | "RGLS" | Common Stock | D | 6,8360 | -1.500 | -10 | 6.077.650 | ||||
| 2014-08-29 | 2014-08-28 | 4 | ALNYLAM PHARMACEUTICALS, INC. | "RGLS" | Common Stock | D | 6,9604 | -2.000 | -14 | 6.079.150 | ||||
| 2014-08-29 | 2014-08-27 | 4 | ALNYLAM PHARMACEUTICALS, INC. | "RGLS" | Common Stock | D | 7,2143 | -1.500 | -11 | 6.081.150 | ||||
| 2014-08-29 | 2014-08-29 | 4 | ISIS PHARMACEUTICALS INC | "RGLS" | Common Stock | D | 6,8360 | -1.500 | -10 | 6.976.650 | ||||
| 2014-08-29 | 2014-08-28 | 4 | ISIS PHARMACEUTICALS INC | "RGLS" | Common Stock | D | 6,9604 | -2.000 | -14 | 6.978.150 | ||||
| 2014-08-29 | 2014-08-27 | 4 | ISIS PHARMACEUTICALS INC | "RGLS" | Common Stock | D | 7,2143 | -1.500 | -11 | 6.980.150 | ||||
| 2014-08-22 | 2014-08-22 | 4 | ALNYLAM PHARMACEUTICALS, INC. | "RGLS" | Common Stock | D | 6,7510 | -5.250 | -35 | 6.082.650 | ||||
| 2014-08-22 | 2014-08-21 | 4 | ALNYLAM PHARMACEUTICALS, INC. | "RGLS" | Common Stock | D | 6,8889 | -2.500 | -17 | 6.087.900 | ||||
| 2014-08-22 | 2014-08-20 | 4 | ALNYLAM PHARMACEUTICALS, INC. | "RGLS" | Common Stock | D | 7,1412 | -3.000 | -21 | 6.090.400 | ||||
| 2014-08-22 | 2014-08-22 | 4 | ISIS PHARMACEUTICALS INC | "RGLS" | Common Stock | D | 6,7510 | -5.250 | -35 | 6.981.650 | ||||
| 2014-08-22 | 2014-08-21 | 4 | ISIS PHARMACEUTICALS INC | "RGLS" | Common Stock | D | 6,8889 | -2.500 | -17 | 6.986.900 | ||||
| 2014-08-22 | 2014-08-20 | 4 | ISIS PHARMACEUTICALS INC | "RGLS" | Common Stock | D | 7,1412 | -3.000 | -21 | 6.989.400 | ||||
| 2014-08-15 | 2014-08-15 | 4 | ALNYLAM PHARMACEUTICALS, INC. | "RGLS" | Common Stock | D | 6,9761 | -1.450 | -10 | 6.093.400 | ||||
| 2014-08-15 | 2014-08-14 | 4 | ALNYLAM PHARMACEUTICALS, INC. | "RGLS" | Common Stock | D | 7,0423 | -1.750 | -12 | 6.094.850 | ||||
| 2014-08-15 | 2014-08-13 | 4 | ALNYLAM PHARMACEUTICALS, INC. | "RGLS" | Common Stock | D | 7,0167 | -2.250 | -16 | 6.096.600 | ||||
| 2014-08-15 | 2014-08-15 | 4 | ISIS PHARMACEUTICALS INC | "RGLS" | Common Stock | D | 6,9761 | -1.450 | -10 | 6.992.400 | ||||
| 2014-08-15 | 2014-08-14 | 4 | ISIS PHARMACEUTICALS INC | "RGLS" | Common Stock | D | 7,0423 | -1.750 | -12 | 6.993.850 | ||||
| 2014-08-15 | 2014-08-13 | 4 | ISIS PHARMACEUTICALS INC | "RGLS" | Common Stock | D | 7,0167 | -2.250 | -16 | 6.995.600 | ||||
| 2014-08-08 | 2014-08-08 | 4 | ALNYLAM PHARMACEUTICALS, INC. | "RGLS" | Common Stock | D | 6,8014 | -1.850 | -13 | 6.098.850 | ||||
| 2014-08-08 | 2014-08-07 | 4 | ALNYLAM PHARMACEUTICALS, INC. | "RGLS" | Common Stock | D | 6,6623 | -2.600 | -17 | 6.100.700 | ||||
| 2014-08-08 | 2014-08-06 | 4 | ALNYLAM PHARMACEUTICALS, INC. | "RGLS" | Common Stock | D | 7,0794 | -3.150 | -22 | 6.103.300 | ||||
| 2014-08-08 | 2014-08-08 | 4 | ISIS PHARMACEUTICALS INC | "RGLS" | Common Stock | D | 6,8014 | -1.850 | -13 | 6.997.850 | ||||
| 2014-08-08 | 2014-08-07 | 4 | ISIS PHARMACEUTICALS INC | "RGLS" | Common Stock | D | 6,6623 | -2.600 | -17 | 6.999.700 | ||||
| 2014-08-08 | 2014-08-06 | 4 | ISIS PHARMACEUTICALS INC | "RGLS" | Common Stock | D | 7,0794 | -3.150 | -22 | 7.002.300 | ||||
| 2014-08-07 | 2014-08-05 | 4 | XANTHOPOULOS KLEANTHIS G | "RGLS" | Stock Option (Right to Buy) | D | 0,38 | -3.505 | 458.802 | |||||
| 2014-08-07 | 2014-08-05 | 4 | XANTHOPOULOS KLEANTHIS G | "RGLS" | Common Stock | D | 7,0583 | -3.505 | -25 | 0 | ||||
| 2014-08-07 | 2014-08-05 | 4 | XANTHOPOULOS KLEANTHIS G | "RGLS" | Common Stock | D | 0,3800 | 3.505 | 1 | 3.505 | ||||
| 2014-08-01 | 2014-08-01 | 4 | ALNYLAM PHARMACEUTICALS, INC. | "RGLS" | Common Stock | D | 6,2125 | -2.600 | -16 | 6.106.450 | ||||
| 2014-08-01 | 2014-07-31 | 4 | ALNYLAM PHARMACEUTICALS, INC. | "RGLS" | Common Stock | D | 6,4198 | -1.750 | -11 | 6.109.050 | ||||
| 2014-08-01 | 2014-07-30 | 4 | ALNYLAM PHARMACEUTICALS, INC. | "RGLS" | Common Stock | D | 6,6021 | -1.000 | -7 | 6.110.800 | ||||
| 2014-08-01 | 2014-08-01 | 4 | ISIS PHARMACEUTICALS INC | "RGLS" | Common Stock | D | 6,2125 | -2.600 | -16 | 7.005.450 | ||||
| 2014-08-01 | 2014-07-31 | 4 | ISIS PHARMACEUTICALS INC | "RGLS" | Common Stock | D | 6,4198 | -1.750 | -11 | 7.008.050 | ||||
| 2014-08-01 | 2014-07-30 | 4 | ISIS PHARMACEUTICALS INC | "RGLS" | Common Stock | D | 6,6021 | -1.000 | -7 | 7.009.800 | ||||
| 2014-07-25 | 2014-07-25 | 4 | ALNYLAM PHARMACEUTICALS, INC. | "RGLS" | Common Stock | D | 6,5509 | -1.700 | -11 | 6.111.800 | ||||
| 2014-07-25 | 2014-07-24 | 4 | ALNYLAM PHARMACEUTICALS, INC. | "RGLS" | Common Stock | D | 6,8097 | -1.850 | -13 | 6.113.500 | ||||
| 2014-07-25 | 2014-07-23 | 4 | ALNYLAM PHARMACEUTICALS, INC. | "RGLS" | Common Stock | D | 6,8835 | -1.700 | -12 | 6.115.350 | ||||
| 2014-07-25 | 2014-07-25 | 4 | ISIS PHARMACEUTICALS INC | "RGLS" | Common Stock | D | 6,5509 | -1.700 | -11 | 7.010.800 | ||||
| 2014-07-25 | 2014-07-24 | 4 | ISIS PHARMACEUTICALS INC | "RGLS" | Common Stock | D | 6,8097 | -1.850 | -13 | 7.012.500 | ||||
| 2014-07-25 | 2014-07-23 | 4 | ISIS PHARMACEUTICALS INC | "RGLS" | Common Stock | D | 6,8835 | -1.700 | -12 | 7.014.350 | ||||
| 2014-07-18 | 2014-07-18 | 4 | ALNYLAM PHARMACEUTICALS, INC. | "RGLS" | Common Stock | D | 6,8002 | -5.000 | -34 | 6.117.050 | ||||
| 2014-07-18 | 2014-07-17 | 4 | ALNYLAM PHARMACEUTICALS, INC. | "RGLS" | Common Stock | D | 6,5812 | -5.000 | -33 | 6.122.050 | ||||
| 2014-07-18 | 2014-07-16 | 4 | ALNYLAM PHARMACEUTICALS, INC. | "RGLS" | Common Stock | D | 6,5881 | -3.500 | -23 | 6.127.050 | ||||
| 2014-07-18 | 2014-07-18 | 4 | ISIS PHARMACEUTICALS INC | "RGLS" | Common Stock | D | 6,8002 | -5.000 | -34 | 7.016.050 | ||||
| 2014-07-18 | 2014-07-17 | 4 | ISIS PHARMACEUTICALS INC | "RGLS" | Common Stock | D | 6,5812 | -5.000 | -33 | 7.021.050 | ||||
| 2014-07-18 | 2014-07-16 | 4 | ISIS PHARMACEUTICALS INC | "RGLS" | Common Stock | D | 6,5881 | -3.500 | -23 | 7.026.050 | ||||
| 2014-07-11 | 2014-07-11 | 4 | ALNYLAM PHARMACEUTICALS, INC. | "RGLS" | Common Stock | D | 6,4797 | -1.750 | -11 | 6.130.550 | ||||
| 2014-07-11 | 2014-07-10 | 4 | ALNYLAM PHARMACEUTICALS, INC. | "RGLS" | Common Stock | D | 6,6908 | -4.500 | -30 | 6.132.300 | ||||
| 2014-07-11 | 2014-07-09 | 4 | ALNYLAM PHARMACEUTICALS, INC. | "RGLS" | Common Stock | D | 7,0824 | -1.800 | -13 | 6.136.800 | ||||
| 2014-07-11 | 2014-07-11 | 4 | ISIS PHARMACEUTICALS INC | "RGLS" | Common Stock | D | 6,4797 | -1.750 | -11 | 7.029.550 | ||||
| 2014-07-11 | 2014-07-10 | 4 | ISIS PHARMACEUTICALS INC | "RGLS" | Common Stock | D | 6,6908 | -4.500 | -30 | 7.031.300 | ||||
| 2014-07-11 | 2014-07-09 | 4 | ISIS PHARMACEUTICALS INC | "RGLS" | Common Stock | D | 7,0824 | -1.800 | -13 | 7.035.800 | ||||
| 2014-07-07 | 2014-07-03 | 4 | ALNYLAM PHARMACEUTICALS, INC. | "RGLS" | Common Stock | D | 8,0653 | -1.200 | -10 | 6.138.600 | ||||
| 2014-07-07 | 2014-07-02 | 4 | ALNYLAM PHARMACEUTICALS, INC. | "RGLS" | Common Stock | D | 8,0680 | -3.100 | -25 | 6.139.800 | ||||
| 2014-07-07 | 2014-07-03 | 4 | ISIS PHARMACEUTICALS INC | "RGLS" | Common Stock | D | 8,0653 | -1.200 | -10 | 7.037.600 | ||||
| 2014-07-07 | 2014-07-02 | 4 | ISIS PHARMACEUTICALS INC | "RGLS" | Common Stock | D | 8,0680 | -3.100 | -25 | 7.038.800 | ||||
| 2014-07-02 | 2014-07-01 | 4 | XANTHOPOULOS KLEANTHIS G | "RGLS" | Stock Option (Right to Buy) | D | 0,38 | -3.505 | 462.307 | |||||
| 2014-07-02 | 2014-07-01 | 4 | XANTHOPOULOS KLEANTHIS G | "RGLS" | Common Stock | D | 8,1100 | -3.505 | -28 | 0 | ||||
| 2014-07-02 | 2014-07-01 | 4 | XANTHOPOULOS KLEANTHIS G | "RGLS" | Common Stock | D | 0,3800 | 3.505 | 1 | 3.505 | ||||
| 2014-07-02 | 2014-07-01 | 4 | Gibson Neil W | "RGLS" | Stock Option (Right to Buy) | D | 1,74 | -2.500 | 124.000 | |||||
| 2014-07-02 | 2014-07-01 | 4 | Gibson Neil W | "RGLS" | Common Stock | D | 8,1040 | -2.500 | -20 | 80.000 | ||||
| 2014-07-02 | 2014-07-01 | 4 | Gibson Neil W | "RGLS" | Common Stock | D | 1,7400 | 2.500 | 4 | 82.500 | ||||
| 2014-06-27 | 2014-06-27 | 4 | ALNYLAM PHARMACEUTICALS, INC. | "RGLS" | Common Stock | D | 7,9146 | -3.150 | -25 | 6.142.900 | ||||
| 2014-06-27 | 2014-06-26 | 4 | ALNYLAM PHARMACEUTICALS, INC. | "RGLS" | Common Stock | D | 7,8870 | -1.700 | -13 | 6.146.050 | ||||
| 2014-06-27 | 2014-06-25 | 4 | ALNYLAM PHARMACEUTICALS, INC. | "RGLS" | Common Stock | D | 7,8421 | -2.750 | -22 | 6.147.750 | ||||
| 2014-06-27 | 2014-06-27 | 4 | ISIS PHARMACEUTICALS INC | "RGLS" | Common Stock | D | 7,9146 | -3.150 | -25 | 7.041.900 | ||||
| 2014-06-27 | 2014-06-26 | 4 | ISIS PHARMACEUTICALS INC | "RGLS" | Common Stock | D | 7,8870 | -1.700 | -13 | 7.045.050 | ||||
| 2014-06-27 | 2014-06-25 | 4 | ISIS PHARMACEUTICALS INC | "RGLS" | Common Stock | D | 7,8421 | -2.750 | -22 | 7.046.750 | ||||
| 2014-06-18 | 2014-03-06 | 4/A | Gibson Neil W | "RGLS" | Stock Option (Right to Buy) | D | 1,74 | -2.500 | 91 | |||||
| 2014-06-18 | 2014-04-09 | 4/A | Gibson Neil W | "RGLS" | Stock Option (Right to Buy) | D | 1,74 | -2.409 | 131.500 | |||||
| 2014-06-18 | 2014-04-09 | 4/A | Gibson Neil W | "RGLS" | Stock Option (Right to Buy) | D | 1,74 | -91 | 0 | |||||
| 2014-06-18 | 2014-06-16 | 4 | GRINT PAUL C | "RGLS" | Employee Stock Option (Right to Buy) | D | 7,58 | 250.000 | 250.000 | |||||
| 2014-06-18 | 2014-06-17 | 4 | Gibson Neil W | "RGLS" | Stock Option (Right to Buy) | D | 1,74 | -5.000 | 126.500 | |||||
| 2014-06-18 | 2014-06-17 | 4 | Gibson Neil W | "RGLS" | Common Stock | D | 8,0454 | -5.000 | -40 | 80.000 | ||||
| 2014-06-18 | 2014-06-17 | 4 | Gibson Neil W | "RGLS" | Common Stock | D | 1,7400 | 5.000 | 9 | 85.000 | ||||
| 2014-06-09 | 2014-06-09 | 4 | XANTHOPOULOS KLEANTHIS G | "RGLS" | Stock Option (Right to Buy) | D | 0,38 | -3.505 | 465.812 | |||||
| 2014-06-09 | 2014-06-09 | 4 | XANTHOPOULOS KLEANTHIS G | "RGLS" | Common Stock | D | 7,1376 | -3.505 | -25 | 0 | ||||
| 2014-06-09 | 2014-06-09 | 4 | XANTHOPOULOS KLEANTHIS G | "RGLS" | Common Stock | D | 0,3800 | 3.505 | 1 | 3.505 | ||||
| 2014-05-29 | 2014-05-29 | 4 | XANTHOPOULOS KLEANTHIS G | "RGLS" | Stock Option (Right to Buy) | D | 0,38 | -887 | 469.317 | |||||
| 2014-05-29 | 2014-05-29 | 4 | XANTHOPOULOS KLEANTHIS G | "RGLS" | Common Stock | D | 7,0000 | -887 | -6 | 0 | ||||
| 2014-05-29 | 2014-05-29 | 4 | XANTHOPOULOS KLEANTHIS G | "RGLS" | Common Stock | D | 0,3800 | 887 | 0 | 887 | ||||
| 2014-05-29 | 2014-05-28 | 4 | XANTHOPOULOS KLEANTHIS G | "RGLS" | Stock Option (Right to Buy) | D | 0,38 | -875 | 470.204 | |||||
| 2014-05-29 | 2014-05-28 | 4 | XANTHOPOULOS KLEANTHIS G | "RGLS" | Common Stock | D | 7,0011 | -875 | -6 | 0 | ||||
| 2014-05-29 | 2014-05-28 | 4 | XANTHOPOULOS KLEANTHIS G | "RGLS" | Common Stock | D | 0,3800 | 875 | 0 | 875 | ||||
| 2014-05-29 | 2014-05-27 | 4 | XANTHOPOULOS KLEANTHIS G | "RGLS" | Stock Option (Right to Buy) | D | 0,38 | -1.743 | 471.079 | |||||
| 2014-05-29 | 2014-05-27 | 4 | XANTHOPOULOS KLEANTHIS G | "RGLS" | Common Stock | D | 7,0011 | -1.743 | -12 | 0 | ||||
| 2014-05-29 | 2014-05-27 | 4 | XANTHOPOULOS KLEANTHIS G | "RGLS" | Common Stock | D | 0,3800 | 1.743 | 1 | 1.743 | ||||
| 2014-05-22 | 2014-05-22 | 4 | CARTER BRUCE L A | "RGLS" | Stock Option (Right to Buy) | D | 6,22 | 17.500 | 17.500 | |||||
| 2014-05-22 | 2014-05-22 | 4 | BALTIMORE DAVID | "RGLS" | Stock Option (Right to Buy) | D | 6,22 | 5.000 | 5.000 | |||||
| 2014-05-22 | 2014-05-22 | 4 | BALTIMORE DAVID | "RGLS" | Stock Option (Right to Buy) | D | 6,22 | 17.500 | 17.500 | |||||
| 2014-05-22 | 2014-05-22 | 4 | PAPADOPOULOS STELIOS | "RGLS" | Stock Option (Right to Buy) | D | 6,22 | 17.500 | 17.500 | |||||
| 2014-05-22 | 2014-05-22 | 4 | FOLETTA MARK G | "RGLS" | Stock Option (Right to Buy) | D | 6,22 | 17.500 | 17.500 | |||||
| 2014-05-22 | 2014-05-22 | 4 | RASTETTER WILLIAM H | "RGLS" | Stock Option (Right to Buy) | D | 6,22 | 17.500 | 17.500 | |||||
| 2014-05-22 | 2014-05-22 | 4 | WILLIAMS DOUGLAS E | "RGLS" | Stock Option (Right to Buy) | D | 6,22 | 17.500 | 17.500 | |||||
| 2014-04-10 | 2014-04-09 | 4 | Gibson Neil W | "RGLS" | Stock Option (Right to Buy) | D | 1,74 | -2.500 | 42.591 | |||||
| 2014-04-10 | 2014-04-09 | 4 | Gibson Neil W | "RGLS" | Common Stock | D | 8,1085 | -2.500 | -20 | 80.000 | ||||
| 2014-04-10 | 2014-04-09 | 4 | Gibson Neil W | "RGLS" | Common Stock | D | 1,7400 | 2.500 | 4 | 82.500 | ||||
| 2014-04-09 | 2014-04-08 | 4 | XANTHOPOULOS KLEANTHIS G | "RGLS" | Stock Option (Right to Buy) | D | 0,38 | -3.505 | 472.822 | |||||
| 2014-04-09 | 2014-03-06 | 4 | XANTHOPOULOS KLEANTHIS G By the Xanthopoulos Family Trust dated September 30, 2011 | "RGLS" | Common Stock | I | 7,5957 | -3.505 | -27 | 80.216 | ||||
| 2014-04-09 | 2014-03-06 | 4 | XANTHOPOULOS KLEANTHIS G By the Xanthopoulos Family Trust dated September 30, 2011 | "RGLS" | Common Stock | I | 0,3800 | 3.505 | 1 | 83.721 | ||||
| 2014-03-07 | 2014-03-06 | 4 | XANTHOPOULOS KLEANTHIS G | "RGLS" | Stock Option (Right to Buy) | D | 0,38 | -3.505 | 476.327 | |||||
| 2014-03-07 | 2014-03-06 | 4 | XANTHOPOULOS KLEANTHIS G By the Xanthopoulos Family Trust dated September 30, 2011 | "RGLS" | Common Stock | I | 11,3490 | -3.505 | -40 | 80.216 | ||||
| 2014-03-07 | 2014-03-06 | 4 | XANTHOPOULOS KLEANTHIS G By the Xanthopoulos Family Trust dated September 30, 2011 | "RGLS" | Common Stock | I | 0,3800 | 3.505 | 1 | 83.721 | ||||
| 2014-03-07 | 2014-03-06 | 4 | Gibson Neil W | "RGLS" | Stock Option (Right to Buy) | D | 1,74 | -2.500 | 45.091 | |||||
| 2014-03-07 | 2014-03-06 | 4 | Gibson Neil W | "RGLS" | Common Stock | D | 11,3714 | -2.500 | -28 | 80.000 | ||||
| 2014-03-07 | 2014-03-06 | 4 | Gibson Neil W | "RGLS" | Common Stock | D | 1,7400 | 2.500 | 4 | 82.500 | ||||
| 2014-02-07 | 2014-02-05 | 4 | XANTHOPOULOS KLEANTHIS G | "RGLS" | Stock Option (Right to Buy) | D | 0,38 | -3.505 | 479.832 | |||||
| 2014-02-07 | 2014-02-05 | 4 | XANTHOPOULOS KLEANTHIS G By the Xanthopoulos Family Trust dated September 30, 2011 | "RGLS" | Common Stock | I | 8,3987 | -3.505 | -29 | 80.216 | ||||
| 2014-02-07 | 2014-02-05 | 4 | XANTHOPOULOS KLEANTHIS G By the Xanthopoulos Family Trust dated September 30, 2011 | "RGLS" | Common Stock | I | 0,3800 | 3.505 | 1 | 83.721 | ||||
| 2014-02-07 | 2014-02-06 | 4 | Gibson Neil W | "RGLS" | Stock Option (Right to Buy) | D | 1,74 | -45.000 | 2.591 | |||||
| 2014-02-07 | 2014-02-06 | 4 | Gibson Neil W | "RGLS" | Common Stock | D | 1,7400 | 45.000 | 78 | 80.000 | ||||
| 2014-02-07 | 2014-02-05 | 4 | Gibson Neil W | "RGLS" | Stock Option (Right to Buy) | D | 1,74 | -2.500 | 47.591 | |||||
| 2014-02-07 | 2014-02-05 | 4 | Gibson Neil W | "RGLS" | Common Stock | D | 8,3832 | -17.500 | -147 | 35.000 | ||||
| 2014-02-07 | 2014-02-05 | 4 | Gibson Neil W | "RGLS" | Common Stock | D | 1,7400 | 2.500 | 4 | 52.500 | ||||
| 2014-02-05 | 2014-02-04 | 4 | Sanofi | RGLS | Common stock, $ 0.001 par value- | I | 7,6700 | 1.303.780 | 10.000 | 5.053.779 | ||||
| 2014-01-23 | 2014-01-21 | 4 | Gibson Neil W | RGLS | Stock Option (Right to Buy) | D | 2,66 | -4.421 | 701 | |||||
| 2014-01-23 | 2014-01-21 | 4 | Gibson Neil W | RGLS | Common Stock | D | 8,0896 | -4.421 | -36 | 50.000 | ||||
| 2014-01-23 | 2014-01-21 | 4 | Gibson Neil W | RGLS | Common Stock | D | 2,6600 | 4.421 | 12 | 54.421 | ||||
| 2014-01-21 | 2014-01-17 | 4 | Gibson Neil W | RGLS | Stock Option (Right to Buy) | D | 2,66 | -2.079 | 5.122 | |||||
| 2014-01-21 | 2014-01-17 | 4 | Gibson Neil W | RGLS | Stock Option (Right to Buy) | D | 1,74 | -2.400 | 50.091 | |||||
| 2014-01-21 | 2014-01-17 | 4 | Gibson Neil W | RGLS | Common Stock | D | 8,1477 | -4.479 | -36 | 50.000 | ||||
| 2014-01-21 | 2014-01-17 | 4 | Gibson Neil W | RGLS | Common Stock | D | 2,6600 | 2.079 | 6 | 54.479 | ||||
| 2014-01-21 | 2014-01-17 | 4 | Gibson Neil W | RGLS | Common Stock | D | 1,7400 | 2.400 | 4 | 52.400 | ||||
| 2014-01-17 | 2014-01-16 | 4 | Gibson Neil W | RGLS | Stock Option (Right to Buy) | D | 1,74 | -1.100 | 52.491 | |||||
| 2014-01-17 | 2014-01-16 | 4 | Gibson Neil W | RGLS | Common Stock | D | 8,0336 | -1.100 | -9 | 50.000 | ||||
| 2014-01-17 | 2014-01-16 | 4 | Gibson Neil W | RGLS | Common Stock | D | 1,7400 | 1.100 | 2 | 51.100 | ||||
| 2014-01-02 | 2014-01-02 | 4 | XANTHOPOULOS KLEANTHIS G | RGLS | Stock Option (Right to Buy) | D | 0,38 | -3.505 | 483.337 | |||||
| 2014-01-02 | 2014-01-02 | 4 | XANTHOPOULOS KLEANTHIS G By the Xanthopoulos Family Trust dated September 30, 2011 | RGLS | Common Stock | I | 7,2492 | -3.505 | -25 | 80.216 | ||||
| 2014-01-02 | 2014-01-02 | 4 | XANTHOPOULOS KLEANTHIS G By the Xanthopoulos Family Trust dated September 30, 2011 | RGLS | Common Stock | I | 0,3800 | 3.505 | 1 | 83.721 | ||||
| 2013-12-16 | 2013-12-16 | 4 | XANTHOPOULOS KLEANTHIS G By the Xanthopoulos Family Trust dated September 30, 2011 | RGLS | Common Stock | I | -2.000 | 80.216 | ||||||
| 2013-12-16 | 2013-12-12 | 4 | XANTHOPOULOS KLEANTHIS G | RGLS | Stock Option (Right to Buy) | D | 6,13 | 220.000 | 220.000 | |||||
| 2013-12-16 | 2013-12-12 | 4 | Gibson Neil W | RGLS | Stock Option (Right to Buy) | D | 6,13 | 100.000 | 100.000 | |||||
| 2013-06-10 | 2013-06-10 | 4 | BALTIMORE DAVID | RGLS | Stock Option (Right to Buy) | D | 9,32 | 5.000 | 5.000 | |||||
| 2013-06-10 | 2013-06-10 | 4 | BALTIMORE DAVID | RGLS | Stock Option (Right to Buy) | D | 9,32 | 17.500 | 17.500 | |||||
| 2013-06-10 | 2013-06-10 | 4 | RASTETTER WILLIAM H | RGLS | Stock Option (Right to Buy) | D | 9,32 | 17.500 | 17.500 | |||||
| 2013-06-10 | 2013-06-10 | 4 | PAPADOPOULOS STELIOS | RGLS | Stock Option (Right to Buy) | D | 9,32 | 17.500 | 17.500 | |||||
| 2013-06-10 | 2013-06-10 | 4 | WILLIAMS DOUGLAS E | RGLS | Stock Option (Right to Buy) | D | 9,32 | 17.500 | 17.500 | |||||
| 2013-06-10 | 2013-06-10 | 4 | FOLETTA MARK G | RGLS | Stock Option (Right to Buy) | D | 9,32 | 17.500 | 17.500 | |||||
| 2013-06-10 | 2013-06-10 | 4 | CARTER BRUCE L A | RGLS | Stock Option (Right to Buy) | D | 9,32 | 17.500 | 17.500 | |||||
| 2013-04-01 | 3 | RASTETTER WILLIAM H | RGLS | Common Stock | D | 0 | ||||||||
| 2013-04-01 | 2013-04-01 | 4 | RASTETTER WILLIAM H | RGLS | Stock Option (Right to Buy) | D | 7,67 | 30.000 | 30.000 | |||||
| 2013-02-14 | 2013-02-04 | 4 | Gibson Neil W | RGLS | Stock Option (Right to Buy) | D | 1,74 | 50.000 | 133.909 | |||||
| 2013-02-14 | 2013-02-04 | 4 | Gibson Neil W | RGLS | Common Stock | D | 1,7400 | 50.000 | 87 | 50.000 | ||||
| 2013-01-31 | 3 | FOLETTA MARK G | RGLS | Common Stock | D | 0 | ||||||||
| 2013-01-31 | 2013-01-30 | 4 | FOLETTA MARK G | RGLS | Stock Option (Right to Buy) | D | 5,98 | 30.000 | 30.000 | |||||
| 2012-12-13 | 2012-12-11 | 4 | XANTHOPOULOS KLEANTHIS G | RGLS | Stock Option (Right to Buy) | D | 4,44 | 150.000 | 150.000 | |||||
| 2012-12-13 | 2012-12-11 | 4 | Gibson Neil W | RGLS | Stock Option (Right to Buy) | D | 4,44 | 112.500 | 112.500 | |||||
| 2012-12-13 | 2012-12-11 | 4 | Menzel Garry E | RGLS | Stock Option (Right to Buy) | D | 4,44 | 75.000 | 75.000 | |||||
| 2012-11-08 | 3 | WILLIAMS DOUGLAS E | RGLS | Common Stock | D | 0 | ||||||||
| 2012-11-08 | 2012-11-07 | 4 | CARTER BRUCE L A | RGLS | Stock Option (Right to Buy) | D | 4,97 | -15.000 | 15.000 | |||||
| 2012-11-08 | 2012-10-31 | 4 | CARTER BRUCE L A | RGLS | Stock Option (Right to Buy) | D | 4,78 | -30.000 | 30.000 | |||||
| 2012-11-08 | 2012-11-05 | 4 | WILLIAMS DOUGLAS E | RGLS | Stock Option (Right to Buy) | D | 5,03 | 30.000 | 30.000 | |||||
| 2012-11-07 | 2012-11-05 | 4 | Greene Barry E | RGLS | Stock Option (Right to Buy) | D | 5,03 | 25.000 | 25.000 | |||||
| 2012-11-07 | 2012-11-05 | 4 | CROOKE STANLEY T | RGLS | Stock Option (Right to Buy) | D | 5,03 | 25.000 | 25.000 | |||||
| 2012-10-12 | 3 | ASTRAZENECA AB | RGLS | COMMON STOCK | I | 6.250.000 | ||||||||
| 2012-10-11 | 2012-10-10 | 4 | PARSHALL B LYNNE | RGLS | Series A Preferred Stock | I | -6.299.500 | 0 | ||||||
| 2012-10-11 | 2012-10-10 | 4 | PARSHALL B LYNNE | RGLS | Common Stock | I | 4,0000 | 750.000 | 3.000 | 7.049.500 | ||||
| 2012-10-11 | 2012-10-10 | 4 | PARSHALL B LYNNE | RGLS | Common Stock | I | 6.299.500 | 6.299.500 | ||||||
| 2012-10-11 | 2012-10-10 | 4 | MARAGANORE JOHN | RGLS | Series A Preferred Stock | I | -6.150.500 | 0 | ||||||
| 2012-10-11 | 2012-10-10 | 4 | MARAGANORE JOHN | RGLS | Common Stock | I | 6.150.500 | 6.150.500 | ||||||
| 2012-10-11 | 2012-10-10 | 4 | Greene Barry E | RGLS | Series A Preferred Stock | I | -6.150.500 | 0 | ||||||
| 2012-10-11 | 2012-10-10 | 4 | Greene Barry E | RGLS | Common Stock | I | 6.150.500 | 6.150.500 | ||||||
| 2012-10-11 | 2012-10-10 | 4 | ALNYLAM PHARMACEUTICALS, INC. | RGLS | Series A Preferred Stock | D | -6.150.500 | 0 | ||||||
| 2012-10-11 | 2012-10-10 | 4 | ALNYLAM PHARMACEUTICALS, INC. | RGLS | Common Stock | D | 6.150.500 | 6.150.500 | ||||||
| 2012-10-11 | 2012-10-10 | 4 | ISIS PHARMACEUTICALS INC | RGLS | Series A Preferred Stock | D | -6.299.500 | 0 | ||||||
| 2012-10-11 | 2012-10-10 | 4 | ISIS PHARMACEUTICALS INC | RGLS | Common Stock | D | 4,0000 | 750.000 | 3.000 | 7.049.500 | ||||
| 2012-10-11 | 2012-10-10 | 4 | ISIS PHARMACEUTICALS INC | RGLS | Common Stock | D | 6.299.500 | 6.299.500 | ||||||
| 2012-10-11 | 2012-10-10 | 4 | CROOKE STANLEY T | RGLS | Series A Preferred Stock | I | -6.299.500 | 0 | ||||||
| 2012-10-11 | 2012-10-10 | 4 | CROOKE STANLEY T | RGLS | Common Stock | I | 4,0000 | 750.000 | 3.000 | 7.049.500 | ||||
| 2012-10-11 | 2012-10-10 | 4 | CROOKE STANLEY T | RGLS | Common Stock | I | 6.299.500 | 6.299.500 | ||||||
| 2012-10-09 | 3 | Sanofi | RGLS | Common Stock | I | 3.749.999 | ||||||||
| 2012-10-04 | 3 | XANTHOPOULOS KLEANTHIS G By the Xanthopoulos Family Trust dated September 30, 2011 | RGLS | Common Stock | I | 82.216 | ||||||||
| 2012-10-04 | 3 | Menzel Garry E By the Garry E. Menzel and Mary E. Henshall Family Trust | RGLS | Common Stock | I | 111.842 |
P
Offener Markt oder privater Kauf von nicht-derivativen oder derivativen Wertpapieren
S
Freiverkauf oder privater Verkauf von nicht-derivativen oder derivativen Wertpapieren
A
Gewährung, Vergabe oder sonstiger Erwerb von Wertpapieren des Unternehmens (z. B. eine Option)
C
Umwandlung von Derivaten
D
Verkauf oder Rückübertragung von Wertpapieren an das Unternehmen
F
Zahlung des Ausübungspreises oder der Steuerschuld mit einem Teil der vom Unternehmen erhaltenen Wertpapiere
G
Schenkung von Wertpapieren durch oder an den Insider
K
Aktien-Swaps und ähnliche Absicherungstransaktionen
M
Ausübung oder Umwandlung eines vom Unternehmen erhaltenen derivativen Wertpapiers (z. B. einer Option)
V
Eine freiwillig auf Formular 4 gemeldete Transaktion
J
Sonstige (mit einer Fußnote zur Beschreibung der Transaktion)
