| Insider-Aktien | 21.101.487 shares |
Insider-Stimmungswert
Der Insider-Stimmungswert ermittelt die Unternehmen, die von Unternehmensinsidern gekauft werden.
Es ist das Ergebnis eines ausgeklügelten quantitativen Multifaktormodells, das die Unternehmen mit der höchsten Insiderakkumulation identifiziert. Das Scoring-Modell verwendet eine Kombination aus der Nettozahl der Insiderkäufe der letzten 90 Tage, der Gesamtzahl der gekauften Aktien als Prozentsatz des Streubesitzes und der Gesamtzahl der von Insidern gehaltenen Aktien. Die Zahl reicht von 0 bis 100, wobei höhere Zahlen ein höheres Maß an Insiderkäufen anzeigen als bei anderen Unternehmen und 50 den Durchschnitt darstellt.
Aktualisierungshäufigkeit: Täglich
Führungskräfte-Stimmungswert
Der Führungskräfte-Stimmungswert findet Unternehmen, die von Führungskräften des Unternehmens gekauft werden.
Per Definition sind Führungskräfte des Unternehmens Insider, aber im Gegensatz zu anderen Insidern (10%ige Aktionäre und Vorstandsmitglieder) arbeiten Führungskräfte täglich für das Unternehmen und verwenden beim Handel ihr eigenes Geld. (10%ige Aktionäre und Vorstandsmitglieder sind oft Fondsmanager, die das Geld anderer Leute verwalten.) Daher sind Insider-Geschäfte, die von Führungskräften getätigt werden, viel bedeutender und sollten entsprechend behandelt werden.
Wie der Insider-Stimmungswert ist auch der Führungskräfte-Stimmungswert das Ergebnis eines ausgeklügelten quantitativen Multifaktormodells, das die Unternehmen mit der höchsten Führungskräftekonzentration identifiziert.
Aktualisierungshäufigkeit: Täglich
Wichtige Insider-Kennzahlen
Diese Karte zeigt, wie das Unternehmen bei verschiedenen Insider-Kennzahlen abschneidet. Der Perzentil-Rang zeigt, wie dieses Unternehmen im Vergleich zu anderen Unternehmen auf den US-Märkten abschneidet. Höhere Ränge deuten auf eine bessere Situation hin.
Es ist beispielsweise allgemein anerkannt, dass Insiderkäufe ein positiver Indikator sind, so dass Unternehmen mit mehr Insiderkäufen besser abschneiden würden als Unternehmen mit weniger Insiderkäufen (oder sogar Insiderverkäufen).
Nettoanzahl der Insider, die kaufen (Rang)
N/A
Die Nettoanzahl der Insiderkäufe ist die Gesamtzahl der Insiderkäufe abzüglich der Gesamtzahl der Insiderverkäufe in den letzten 90 Tagen. Der Perzentilrang wird hier angezeigt (Bereich von 0 bis 100%).
Prozent des Streubesitzes von Insidern gekauft (Rang)
N/A
Prozent des von Insidern gekauften Streubesitzes ist die Gesamtzahl der von Insidern gekauften Aktien abzüglich der Gesamtzahl der von Insidern in den letzten 90 Tagen verkauften Aktien, geteilt durch den gesamten Streubesitz und multipliziert mit 100.
Diagramm zum Insiderhandel
Tobira Therapeutics, Inc. Insider-Trades sind in der folgenden Grafik dargestellt. Insider sind leitende Angestellte, Direktoren oder bedeutende Investoren in einem Unternehmen. Im Allgemeinen ist es für Insider illegal, auf der Grundlage von wesentlichen, nicht-öffentlichen Informationen mit Aktien ihrer Unternehmen zu handeln. Das bedeutet nicht, dass es für sie illegal ist, irgendwelche Geschäfte in ihren eigenen Unternehmen zu tätigen. Sie müssen jedoch alle Geschäfte der SEC über ein Formular 4 melden.
Kennzahlen zu Insiderlisten und Rentabilität
Diese Tabelle zeigt die Liste der bekannten Insider und wird automatisch aus den bei der SEC eingereichten Unterlagen erstellt. Zusätzlich zu den Namen, dem letzten Titel und der Bezeichnung als Direktor, leitender Angestellter oder 10%-iger Anteilseigner geben wir die zuletzt veröffentlichten Bestände an. Zusätzlich stellen wir, wenn möglich, die historische Handelsperformance für den Insider zur Verfügung. Die historische Handelsperformance ist ein gewichteter Durchschnitt der Performance tatsächlicher offener Kauftransaktionen, die von dem Insider getätigt wurden. Weitere Informationen zur Berechnung dieses Wertes finden Sie in diesem YouTube-Webinar.
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| Insider | Durchschnittlicher Gewinn (%) | Aktien in Besitz |
Split Angepasst |
|---|
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Erfolgsbilanz der Insiderkäufe - Kurzfristige Gewinnanalyse
In diesem Abschnitt analysieren wir die Rentabilität jedes ungeplanten Insiderkaufs, der auf dem freien Markt in TBRA / Tobira Therapeutics, Inc. getätigt wurde. Diese Analyse hilft zu verstehen, ob der Insider beständig abnormale Renditen erzielt und es sich lohnt, ihm zu folgen. Diese Analyse bezieht sich auf ein Jahr nach jedem Handel, und die Ergebnisse sind theoretisch .
Die folgende Tabelle zeigt die jüngsten Käufe am offenen Markt, die nicht Teil eines automatischen Handelsplans waren.
Bereinigter Preis ist der splitbereinigte Preis. Bereinigte Aktien sind die um den Split bereinigten Aktien.
Erfolgsbilanz von Insiderverkäufen - Kurzfristige Verlustanalyse
In diesem Abschnitt analysieren wir die kurzfristige Verlustvermeidung jedes ungeplanten Insider-Verkaufs auf dem freien Markt in TBRA / Tobira Therapeutics, Inc.. Ein konsistentes Muster der Verlustvermeidung kann darauf hindeuten, dass zukünftige Verkaufstransaktionen Kursrückgänge vorhersagen können. Diese Analyse bezieht sich auf ein Jahr nach jedem Handel, und die Ergebnisse sind theoretisch .
Die folgende Tabelle zeigt die jüngsten Verkäufe am offenen Markt, die nicht Teil eines automatischen Handelsplans waren.
Bereinigter Preis ist der splitbereinigte Preis. Bereinigte Aktien sind die um den Split bereinigten Aktien.
Transaktionshistorie
Klicken Sie auf das Link-Symbol, um den vollständigen Transaktionsverlauf anzuzeigen. Transaktionen, die im Rahmen eines automatischen Handelsplans 10b5-1 gemeldet werden, sind in der Spalte 10b-5 mit einem X gekennzeichnet.
| Datei Datum |
Handel Datum |
Form | Insider | Ticker | Wertpapier-Titel | Code | Direkt | Ausführung Preis |
Einheit Preis |
Eimheiten Verändert |
Wert Geändert (1K) |
Verbleibende Optionen |
Verbleibende Aktien |
|
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2016-11-04 | 2016-11-01 | 4 | DOMAIN ASSOCIATES Held by Jesse I. Treu | TBRA | Stock Option (Right to Buy) | I | 8,19 | 17.695 | 0 | |||||
| 2016-11-04 | 2016-11-01 | 4 | DOMAIN ASSOCIATES Held by Jesse I. Treu | TBRA | Stock Option (Right to Buy) | I | 42,93 | 1.071 | 0 | |||||
| 2016-11-04 | 2016-11-01 | 4 | DOMAIN ASSOCIATES Held by Jesse I. Treu | TBRA | Stock Option (Right to Buy) | I | 36,00 | 1.996 | 0 | |||||
| 2016-11-04 | 2016-11-01 | 4 | DOMAIN ASSOCIATES | TBRA | Common Stock | D | 28,3500 | -38.094 | -1.080 | 0 | ||||
| 2016-11-03 | 2016-11-01 | 4 | Domain Partners VI, L.P. | TBRA | Common Stock | D | 28,3500 | -285.679 | -8.099 | 0 | ||||
| 2016-11-03 | 2016-11-01 | 4 | DP VI Associates, L.P. | TBRA | Common Stock | D | 28,3500 | -1.657 | -47 | 0 | ||||
| 2016-11-03 | 2016-11-01 | 4 | WEBER ECKARD | TBRA | Employee Stock Option (Right to Buy) | D | 7,91 | -17.778 | 0 | |||||
| 2016-11-03 | 2016-11-01 | 4 | WEBER ECKARD | TBRA | Employee Stock Option (Right to Buy) | D | 16,52 | -15.500 | 0 | |||||
| 2016-11-03 | 2016-11-01 | 4 | WEBER ECKARD | TBRA | Employee Stock Option (Right to Buy) | D | 2,96 | -4.332 | 0 | |||||
| 2016-11-03 | 2016-11-01 | 4 | WEBER ECKARD By Eckard Weber, M.D., Trustee of the Eckard Weber Living Trust UTA dated November 20, 2007 | TBRA | Common Stock, par value $0.001 | I | -243.726 | 0 | ||||||
| 2016-11-03 | 2016-11-01 | 4 | Cooper Jeffrey H | TBRA | Employee Stock Option (Right to Buy) | D | 7,91 | -17.778 | 0 | |||||
| 2016-11-03 | 2016-11-01 | 4 | Cooper Jeffrey H | TBRA | Employee Stock Option (Right to Buy) | D | 16,52 | -15.500 | 0 | |||||
| 2016-11-03 | 2016-11-01 | 4 | Cooper Jeffrey H | TBRA | Employee Stock Option (Right to Buy) | D | 8,13 | -13.539 | 0 | |||||
| 2016-11-03 | 2016-11-01 | 4 | Podlesak Dennis | TBRA | Employee Stock Option (Right to Buy) | D | 8,19 | -17.695 | 0 | |||||
| 2016-11-03 | 2016-11-01 | 4 | Podlesak Dennis | TBRA | Employee Stock Option (Right to Buy) | D | 34,56 | -2.947 | 0 | |||||
| 2016-11-03 | 2016-11-01 | 4 | Podlesak Dennis | TBRA | Employee Stock Option (Right to Buy) | D | 7,91 | -53.334 | 0 | |||||
| 2016-11-03 | 2016-11-01 | 4 | Podlesak Dennis | TBRA | Employee Stock Option (Right to Buy) | D | 16,52 | -27.500 | 0 | |||||
| 2016-11-03 | 2016-11-01 | 4 | Podlesak Dennis | TBRA | Employee Stock Option (Right to Buy) | D | 42,93 | -1.071 | 0 | |||||
| 2016-11-03 | 2016-11-01 | 4 | Podlesak Dennis | TBRA | Employee Stock Option (Right to Buy) | D | 36,00 | -40.733 | 0 | |||||
| 2016-11-03 | 2016-11-01 | 4 | Podlesak Dennis | TBRA | Employee Stock Option (Right to Buy) | D | 40,59 | -10.253 | 0 | |||||
| 2016-11-03 | 2016-11-01 | 4 | Podlesak Dennis | TBRA | Employee Stock Option (Right to Buy) | D | 105,21 | -232 | 0 | |||||
| 2016-11-03 | 2016-11-01 | 4 | Podlesak Dennis | TBRA | Employee Stock Option (Right to Buy) | D | 112,77 | -232 | 0 | |||||
| 2016-11-03 | 2016-11-01 | 4 | Podlesak Dennis | TBRA | Employee Stock Option (Right to Buy) | D | 112,77 | -9.314 | 0 | |||||
| 2016-11-03 | 2016-11-01 | 4 | Frazier Healthcare V, LP | TBRA | Common Stock | D | 28,3500 | -2.668.570 | -75.654 | 0 | ||||
| 2016-11-03 | 2016-11-01 | 4 | Fromkin Andrew J. | TBRA | Employee Stock Option (Right to Buy) | D | 8,19 | -17.695 | 0 | |||||
| 2016-11-03 | 2016-11-01 | 4 | Fromkin Andrew J. | TBRA | Employee Stock Option (Right to Buy) | D | 7,91 | -17.778 | 0 | |||||
| 2016-11-03 | 2016-11-01 | 4 | Fromkin Andrew J. | TBRA | Employee Stock Option (Right to Buy) | D | 16,52 | -15.500 | 0 | |||||
| 2016-11-03 | 2016-11-01 | 4 | Fromkin Andrew J. | TBRA | Employee Stock Option (Right to Buy) | D | 58,23 | -5.666 | 0 | |||||
| 2016-11-03 | 2016-11-01 | 4 | Fromkin Andrew J. Held by children of Reporting Person | TBRA | Common Stock, par value $0.001 | I | -5 | 0 | ||||||
| 2016-11-03 | 2016-11-01 | 4 | Fromkin Andrew J. | TBRA | Common Stock, par value $0.001 | D | -11 | 0 | ||||||
| 2016-11-03 | 2016-11-01 | 4 | Heron Patrick J | TBRA | Employee Stock Option (Right to Buy) | D | 7,91 | -17.778 | 0 | |||||
| 2016-11-03 | 2016-11-01 | 4 | Heron Patrick J | TBRA | Employee Stock Option (Right to Buy) | D | 16,52 | -15.500 | 0 | |||||
| 2016-11-03 | 2016-11-01 | 4 | Heron Patrick J | TBRA | Employee Stock Option (Right to Buy) | D | 2,96 | -4.332 | 0 | |||||
| 2016-11-03 | 2016-11-01 | 4 | DP VII ASSOCIATES LP | TBRA | Common Stock | D | 28,3500 | -47.613 | -1.350 | 0 | ||||
| 2016-11-03 | 2016-11-01 | 4 | DOMAIN PARTERS VII L P | TBRA | Common Stock | D | 28,3500 | -3.553.322 | -100.737 | 0 | ||||
| 2016-11-03 | 2016-11-01 | 4 | Fischer Laurent | TBRA | Employee Stock Option (Right to Buy) | D | 7,91 | -258.000 | 0 | |||||
| 2016-11-03 | 2016-11-01 | 4 | Fischer Laurent | TBRA | Employee Stock Option (Right to Buy) | D | 14,00 | -105.000 | 0 | |||||
| 2016-11-03 | 2016-11-01 | 4 | Fischer Laurent | TBRA | Employee Stock Option (Right to Buy) | D | 4,81 | -503.882 | 0 | |||||
| 2016-11-03 | 2016-11-01 | 4 | Fischer Laurent | TBRA | Employee Stock Option (Right to Buy) | D | 4,81 | -83.324 | 0 | |||||
| 2016-11-03 | 2016-11-01 | 4 | Fischer Laurent | TBRA | Employee Stock Option (Right to Buy) | D | 3,14 | -16.416 | 0 | |||||
| 2016-11-03 | 2016-11-01 | 4 | Fischer Laurent | TBRA | Employee Stock Option (Right to Buy) | D | 3,14 | -53.616 | 0 | |||||
| 2016-11-03 | 2016-11-01 | 4 | Fischer Laurent | TBRA | Employee Stock Option (Right to Buy) | D | 3,14 | -4.332 | 0 | |||||
| 2016-11-03 | 2016-11-01 | 4 | Fischer Laurent | TBRA | Employee Stock Option (Right to Buy) | D | 2,96 | -4.332 | 0 | |||||
| 2016-11-03 | 2016-11-01 | 4 | Legault Pierre | TBRA | Employee Stock Option (Right to Buy) | D | 8,19 | -17.695 | 0 | |||||
| 2016-11-03 | 2016-11-01 | 4 | Legault Pierre | TBRA | Employee Stock Option (Right to Buy) | D | 7,91 | -17.778 | 0 | |||||
| 2016-11-03 | 2016-11-01 | 4 | Legault Pierre | TBRA | Employee Stock Option (Right to Buy) | D | 16,52 | -15.500 | 0 | |||||
| 2016-11-03 | 2016-11-01 | 4 | Legault Pierre | TBRA | Employee Stock Option (Right to Buy) | D | 42,93 | -535 | 0 | |||||
| 2016-11-03 | 2016-11-01 | 4 | Legault Pierre | TBRA | Employee Stock Option (Right to Buy) | D | 43,83 | -6.111 | 0 | |||||
| 2016-11-03 | 2016-11-01 | 4 | Brosgart Carol L | TBRA | Employee Stock Option (Right to Buy) | D | 7,91 | -17.778 | 0 | |||||
| 2016-11-03 | 2016-11-01 | 4 | Brosgart Carol L | TBRA | Employee Stock Option (Right to Buy) | D | 16,52 | -15.500 | 0 | |||||
| 2016-11-03 | 2016-11-01 | 4 | Brosgart Carol L | TBRA | Employee Stock Option (Right to Buy) | D | 4,81 | -18.956 | 0 | |||||
| 2016-11-03 | 2016-11-01 | 4 | Brosgart Carol L | TBRA | Employee Stock Option (Right to Buy) | D | 4,25 | -4.332 | 0 | |||||
| 2016-11-03 | 2016-11-01 | 4 | Brosgart Carol L | TBRA | Employee Stock Option (Right to Buy) | D | 3,14 | -4.332 | 0 | |||||
| 2016-11-03 | 2016-11-01 | 4 | Jenkins Helen | TBRA | Employee Stock Option (Right to Buy) | D | 7,91 | -101.000 | 0 | |||||
| 2016-11-03 | 2016-11-01 | 4 | Jenkins Helen | TBRA | Employee Stock Option (Right to Buy) | D | 14,00 | -65.000 | 0 | |||||
| 2016-11-03 | 2016-11-01 | 4 | Jenkins Helen | TBRA | Employee Stock Option (Right to Buy) | D | 4,81 | -29.841 | 0 | |||||
| 2016-11-03 | 2016-11-01 | 4 | Jenkins Helen | TBRA | Employee Stock Option (Right to Buy) | D | 3,51 | -29.548 | 0 | |||||
| 2016-11-03 | 2016-11-01 | 4 | Peetz Christopher | TBRA | Employee Stock Option (Right to Buy) | D | 7,91 | -101.000 | 0 | |||||
| 2016-11-03 | 2016-11-01 | 4 | Peetz Christopher | TBRA | Employee Stock Option (Right to Buy) | D | 14,00 | -85.000 | 0 | |||||
| 2016-11-03 | 2016-11-01 | 4 | Peetz Christopher | TBRA | Employee Stock Option (Right to Buy) | D | 4,81 | -31.091 | 0 | |||||
| 2016-11-03 | 2016-11-01 | 4 | Peetz Christopher | TBRA | Employee Stock Option (Right to Buy) | D | 4,81 | -68.732 | 0 | |||||
| 2016-11-03 | 2016-11-01 | 4 | Lefebvre Eric | TBRA | Employee Stock Option (Right to Buy) | D | 7,91 | -101.000 | 0 | |||||
| 2016-11-03 | 2016-11-01 | 4 | Lefebvre Eric | TBRA | Employee Stock Option (Right to Buy) | D | 14,00 | -100.000 | 0 | |||||
| 2016-11-03 | 2016-11-01 | 4 | Lefebvre Eric | TBRA | Employee Stock Option (Right to Buy) | D | 3,51 | -79.287 | 0 | |||||
| 2016-11-03 | 2016-11-01 | 4 | Melincoff Gwen A | TBRA | Employee Stock Option (Right to Buy) | D | 7,91 | -17.778 | 0 | |||||
| 2016-11-03 | 2016-11-01 | 4 | Melincoff Gwen A | TBRA | Employee Stock Option (Right to Buy) | D | 16,52 | -15.500 | 0 | |||||
| 2016-11-03 | 2016-11-01 | 4 | Melincoff Gwen A | TBRA | Employee Stock Option (Right to Buy) | D | 8,13 | -13.539 | 0 | |||||
| 2016-11-02 | 2016-10-31 | 4 | Pentwater Capital Management LP By managed account | TBRA | Common Stock, par value $0.001 per share | I | 42,1000 | 5.000 | 210 | 3.758.200 | ||||
| 2016-11-02 | 2016-10-31 | 4 | Pentwater Capital Management LP By managed account | TBRA | Common Stock, par value $0.001 per share | I | 41,7100 | 10.000 | 417 | 3.753.200 | ||||
| 2016-10-19 | 2016-10-18 | 4 | Pentwater Capital Management LP By managed account | TBRA | Common Stock, par value $0.001 per share | I | 40,0400 | 8.300 | 332 | 3.743.200 | ||||
| 2016-10-19 | 2016-10-17 | 4 | Pentwater Capital Management LP By managed account | TBRA | Common Stock, par value $0.001 per share | I | 40,1000 | 27.400 | 1.099 | 3.734.900 | ||||
| 2016-10-19 | 2016-10-17 | 4 | Pentwater Capital Management LP By managed account | TBRA | Common Stock, par value $0.001 per share | I | 39,8900 | 4.300 | 172 | 3.707.500 | ||||
| 2016-10-06 | 2016-10-04 | 4 | Pentwater Capital Management LP By managed account | TBRA | Common Stock, par value $0.001 per share | I | 39,8300 | 4.481 | 178 | 3.703.200 | ||||
| 2016-09-30 | 2016-09-29 | 4 | Pentwater Capital Management LP By managed account | TBRA | Common Stock, par value $0.001 per share | I | 39,4900 | 9.019 | 356 | 3.698.719 | ||||
| 2016-09-30 | 2016-09-29 | 4 | Pentwater Capital Management LP By managed account | TBRA | Common Stock, par value $0.001 per share | I | 39,4900 | 6.500 | 257 | 3.689.700 | ||||
| 2016-09-29 | 3 | Sapphire Acquisition Corp. See Footnotes | TBRA | Common Stock, par value $0.001 | I | 0 | ||||||||
| 2016-09-28 | 2016-09-26 | 4 | Pentwater Capital Management LP By managed account | TBRA | Common Stock, par value $0.001 per share | I | 39,0000 | 49.400 | 1.927 | 3.683.200 | ||||
| 2016-09-28 | 2016-09-26 | 4 | Pentwater Capital Management LP By managed account | TBRA | Common Stock, par value $0.001 per share | I | 39,0100 | 600 | 23 | 3.633.800 | ||||
| 2016-09-23 | 2016-09-23 | 4 | Pentwater Capital Management LP By managed account | TBRA | Common Stock, par value $0.001 per share | I | 39,0900 | 5.000 | 195 | 3.633.200 | ||||
| 2016-09-23 | 2016-09-23 | 4 | Pentwater Capital Management LP By managed account | TBRA | Common Stock, par value $0.001 per share | I | 39,1900 | 95.000 | 3.723 | 3.628.200 | ||||
| 2016-09-22 | 3 | Pentwater Capital Management LP By managed account | TBRA | Common Stock, par value $0.001 per share | I | 3.818.000 | ||||||||
| 2016-09-22 | 3 | Pentwater Capital Management LP By managed account | TBRA | Common Stock, par value $0.001 per share | I | 3.818.000 | ||||||||
| 2016-09-22 | 2016-09-22 | 4 | Pentwater Capital Management LP By managed account | TBRA | Common Stock, par value $0.001 per share | I | 39,4500 | 20.000 | 789 | 3.533.200 | ||||
| 2016-09-22 | 2016-09-22 | 4 | Pentwater Capital Management LP By managed account | TBRA | Common Stock, par value $0.001 per share | I | 39,4000 | 27.791 | 1.095 | 3.513.200 | ||||
| 2016-09-22 | 2016-09-22 | 4 | Pentwater Capital Management LP By managed account | TBRA | Common Stock, par value $0.001 per share | I | 39,3000 | 50.000 | 1.965 | 3.485.409 | ||||
| 2016-09-22 | 2016-09-22 | 4 | Pentwater Capital Management LP By managed account | TBRA | Common Stock, par value $0.001 per share | I | 39,2600 | 1.209 | 47 | 3.435.409 | ||||
| 2016-09-22 | 2016-09-21 | 4 | Pentwater Capital Management LP By Matthew Halbower | TBRA | Common Stock, par value $0.001 per share | I | 39,1400 | 195.000 | 7.632 | 3.434.200 | ||||
| 2016-09-22 | 2016-09-21 | 4 | Pentwater Capital Management LP By managed account | TBRA | Common Stock, par value $0.001 per share | I | 38,9700 | 31.000 | 1.208 | 3.239.200 | ||||
| 2016-09-22 | 2016-09-21 | 4 | Pentwater Capital Management LP By David Pickering | TBRA | Common Stock, par value $0.001 per share | I | 39,1200 | 3.200 | 125 | 3.208.200 | ||||
| 2016-09-22 | 2016-09-20 | 4 | Pentwater Capital Management LP By Matthew Halbower | TBRA | Common Stock, par value $0.001 per share | I | 39,0700 | 5.000 | 195 | 3.205.000 | ||||
| 2016-09-22 | 2016-09-20 | 4 | Pentwater Capital Management LP By managed account | TBRA | Common Stock, par value $0.001 per share | I | 38,8700 | 220.000 | 8.551 | 3.200.000 | ||||
| 2016-09-22 | 2016-09-20 | 4 | Pentwater Capital Management LP By managed account | TBRA | Common Stock, par value $0.001 per share | I | 39,2300 | 1.000 | 39 | 2.980.000 | ||||
| 2016-09-22 | 2016-09-20 | 4 | Pentwater Capital Management LP By managed account | TBRA | Common Stock, par value $0.001 per share | I | 39,0300 | 1.070.000 | 41.762 | 2.979.000 | ||||
| 2016-07-13 | 2016-07-13 | 4 | Novo A/S | TBRA | Common Stock | D | 11,8774 | -29.884 | -355 | 1.875.905 | ||||
| 2016-07-13 | 2016-07-12 | 4 | Novo A/S | TBRA | Common Stock | D | 12,1198 | -8.752 | -106 | 1.905.789 | ||||
| 2016-07-13 | 2016-07-11 | 4 | Novo A/S | TBRA | Common Stock | D | 12,1923 | -20.431 | -249 | 1.914.541 | ||||
| 2016-07-07 | 2016-07-07 | 4 | Novo A/S | TBRA | Common Stock | D | 12,0330 | -21.869 | -263 | 1.934.972 | ||||
| 2016-07-07 | 2016-07-06 | 4 | Novo A/S | TBRA | Common Stock | D | 12,2017 | -59.850 | -730 | 1.956.841 | ||||
| 2016-07-07 | 2016-07-05 | 4 | Novo A/S | TBRA | Common Stock | D | 12,5682 | -10.400 | -131 | 2.016.691 | ||||
| 2016-06-30 | 2016-06-30 | 4 | Novo A/S | TBRA | Common Stock | D | 12,5813 | -27.133 | -341 | 2.027.091 | ||||
| 2016-06-30 | 2016-06-29 | 4 | Novo A/S | TBRA | Common Stock | D | 12,6305 | -16.068 | -203 | 2.054.224 | ||||
| 2016-06-30 | 2016-06-28 | 4 | Novo A/S | TBRA | Common Stock | D | 14,2765 | -2.730 | -39 | 2.070.292 | ||||
| 2016-06-30 | 2016-06-28 | 4 | Novo A/S | TBRA | Common Stock | D | 13,7744 | -20.883 | -288 | 2.073.022 | ||||
| 2016-06-07 | 2016-06-06 | 4 | Novo A/S | TBRA | Common Stock | D | 10,3675 | -187.500 | -1.944 | 2.093.905 | ||||
| 2016-03-04 | 2016-03-04 | 4 | Novo A/S | TBRA | Common Stock | D | 6,5394 | -55.000 | -360 | 2.281.405 | ||||
| 2016-03-04 | 2016-03-03 | 4 | Novo A/S | TBRA | Common Stock | D | 6,8558 | -25.000 | -171 | 2.336.405 | ||||
| 2016-03-04 | 2016-03-02 | 4 | Novo A/S | TBRA | Common Stock | D | 6,9184 | -110.000 | -761 | 2.361.405 | ||||
| 2016-01-14 | 2016-01-12 | 4 | Jenkins Helen | TBRA | Stock Options (right to buy) | D | 7,91 | 101.000 | 101.000 | |||||
| 2016-01-14 | 2016-01-12 | 4 | Peetz Christopher | TBRA | Stock Options (right to buy) | D | 7,91 | 101.000 | 101.000 | |||||
| 2016-01-14 | 2016-01-12 | 4 | Lefebvre Eric | TBRA | Stock Options (right to buy) | D | 7,91 | 101.000 | 101.000 | |||||
| 2016-01-14 | 2016-01-12 | 4 | Fischer Laurent | TBRA | Stock Options (right to buy) | D | 7,91 | 258.000 | 258.000 | |||||
| 2016-01-14 | 2016-01-12 | 4 | Melincoff Gwen A | TBRA | Stock Options (right to buy) | D | 7,91 | 17.778 | 17.778 | |||||
| 2016-01-14 | 2016-01-12 | 4 | Brosgart Carol L | TBRA | Stock Options (right to buy) | D | 7,91 | 17.778 | 17.778 | |||||
| 2016-01-14 | 2016-01-12 | 4 | Heron Patrick J | TBRA | Stock Options (right to buy) | D | 7,91 | 17.778 | 17.778 | |||||
| 2016-01-14 | 2016-01-12 | 4 | Fromkin Andrew J. | TBRA | Stock Options (right to buy) | D | 7,91 | 17.778 | 17.778 | |||||
| 2016-01-14 | 2016-01-12 | 4 | Legault Pierre | TBRA | Stock Options (right to buy) | D | 7,91 | 17.778 | 17.778 | |||||
| 2016-01-14 | 2016-01-12 | 4 | Podlesak Dennis | TBRA | Stock Options (right to buy) | D | 7,91 | 53.334 | 53.334 | |||||
| 2016-01-14 | 2016-01-12 | 4 | Cooper Jeffrey H | TBRA | Stock Options (right to buy) | D | 7,91 | 17.778 | 17.778 | |||||
| 2016-01-14 | 2016-01-12 | 4 | WEBER ECKARD | TBRA | Stock Options (right to buy) | D | 7,91 | 17.778 | 17.778 | |||||
| 2015-12-18 | 3 | Shah Nimesh By Domain Associates, LLC | TBRA | Common Stock | I | 76.188 | ||||||||
| 2015-12-18 | 3 | Shah Nimesh By Domain Associates, LLC | TBRA | Common Stock | I | 76.188 | ||||||||
| 2015-11-19 | 2015-11-18 | 4 | Novo A/S | TBRA | Common Stock | D | 9,7570 | -153.601 | -1.499 | 2.471.405 | ||||
| 2015-11-19 | 2015-11-17 | 4 | Novo A/S | TBRA | Common Stock | D | 9,8656 | -71.399 | -704 | 2.625.006 | ||||
| 2015-07-13 | 2015-07-09 | 4 | Podlesak Dennis | TBRA | Stock Options (right to buy) | D | 16,52 | 27.500 | 27.500 | |||||
| 2015-07-13 | 2015-07-09 | 4 | Fromkin Andrew J. | TBRA | Stock Options (right to buy) | D | 16,52 | 15.500 | 15.500 | |||||
| 2015-07-13 | 2015-07-09 | 4 | Legault Pierre | TBRA | Stock Options (right to buy) | D | 16,52 | 15.500 | 15.500 | |||||
| 2015-07-13 | 2015-07-09 | 4 | Melincoff Gwen A | TBRA | Stock Options (right to buy) | D | 16,52 | 15.500 | 15.500 | |||||
| 2015-07-13 | 2015-07-09 | 4 | Brosgart Carol L | TBRA | Stock Options (right to buy) | D | 16,52 | 15.500 | 15.500 | |||||
| 2015-07-13 | 2015-07-09 | 4 | Heron Patrick J | TBRA | Stock Options (right to buy) | D | 16,52 | 15.500 | 15.500 | |||||
| 2015-07-13 | 2015-07-09 | 4 | Cooper Jeffrey H | TBRA | Stock Options (right to buy) | D | 16,52 | 15.500 | 15.500 | |||||
| 2015-07-13 | 2015-07-09 | 4 | WEBER ECKARD | TBRA | Stock Options (right to buy) | D | 16,52 | 15.500 | 15.500 | |||||
| 2015-05-18 | 2015-05-15 | 4 | Fischer Laurent | TBRA | Stock Options (right to buy) | D | 14,00 | 105.000 | 105.000 | |||||
| 2015-05-18 | 2015-05-15 | 4 | Jenkins Helen | TBRA | Stock Options (right to buy) | D | 14,00 | 65.000 | 65.000 | |||||
| 2015-05-18 | 2015-05-15 | 4 | Peetz Christopher | TBRA | Stock Options (right to buy) | D | 14,00 | 85.000 | 85.000 | |||||
| 2015-05-18 | 2015-05-15 | 4 | Lefebvre Eric | TBRA | Stock Options (right to buy) | D | 14,00 | 100.000 | 100.000 | |||||
| 2015-05-07 | 2015-05-04 | 4/A | WEBER ECKARD | TBRA | Stock Options (right to buy) | D | 2,96 | 4.332 | 4.332 | |||||
| 2015-05-07 | 2015-05-04 | 4/A | WEBER ECKARD By Eckard Weber, M.D., Trustee of the Eckard Weber Living Trust UTA dated November 20, 2007 | TBRA | Common Stock | I | 243.726 | 243.726 | ||||||
| 2015-05-07 | 3 | WEBER ECKARD | TBRA | Common Stock | D | 0 | ||||||||
| 2015-05-07 | 2015-05-04 | 4 | WEBER ECKARD | TBRA | Stock Options (right to buy) | D | 2,96 | 4.332 | 4.332 | |||||
| 2015-05-07 | 2015-05-04 | 4 | WEBER ECKARD By DP VII Associates, L.P. | TBRA | Common Stock | I | 47.613 | 47.613 | ||||||
| 2015-05-07 | 2015-05-04 | 4 | WEBER ECKARD By Domain Partners VII, L.P. | TBRA | Common Stock | I | 3.553.322 | 3.553.322 | ||||||
| 2015-05-07 | 2015-05-04 | 4 | WEBER ECKARD By Domain Associates, L.L.C. | TBRA | Common Stock | I | 36.187 | 36.187 | ||||||
| 2015-05-07 | 2015-05-04 | 4 | WEBER ECKARD By Eckard Weber, M.D., Trustee of the Eckard Weber Living Trust UTA dated November 20, 2007 | TBRA | Common Stock | I | 243.726 | 243.726 | ||||||
| 2015-05-06 | 3 | Peetz Christopher | TBRA | Common Stock | D | 0 | ||||||||
| 2015-05-06 | 3 | Fischer Laurent | TBRA | Common Stock | D | 0 | ||||||||
| 2015-05-06 | 3 | Frazier Healthcare V, LP | TBRA | Common Stock | D | 0 | ||||||||
| 2015-05-06 | 3 | Lefebvre Eric | TBRA | Common Stock | D | 0 | ||||||||
| 2015-05-06 | 3 | Brosgart Carol L | TBRA | Common Stock | D | 0 | ||||||||
| 2015-05-06 | 3 | Melincoff Gwen A | TBRA | Common Stock | D | 0 | ||||||||
| 2015-05-06 | 3 | Jenkins Helen | TBRA | Common Stock | D | 0 | ||||||||
| 2015-05-06 | 3 | Novo A/S | TBRA | COMMON STOCK | D | 3.716.728 | ||||||||
| 2015-05-06 | 3 | Novo A/S | TBRA | COMMON STOCK | D | 3.716.728 | ||||||||
| 2015-05-06 | 3 | Cooper Jeffrey H | TBRA | Common Stock | D | 0 | ||||||||
| 2015-05-06 | 3 | Heron Patrick J | TBRA | Common Stock | D | 0 | ||||||||
| 2015-05-06 | 3 | Halak Brian K | TBRA | Common Stock | D | 95.226 | ||||||||
| 2015-05-06 | 3 | Halak Brian K | TBRA | Common Stock | D | 95.226 | ||||||||
| 2015-05-06 | 3 | Halak Brian K | TBRA | Common Stock | D | 95.226 | ||||||||
| 2015-05-06 | 3 | Halak Brian K | TBRA | Common Stock | D | 95.226 | ||||||||
| 2015-05-06 | 3 | Halak Brian K | TBRA | Common Stock | D | 95.226 | ||||||||
| 2015-05-06 | 3 | Halak Brian K | TBRA | Common Stock | D | 95.226 | ||||||||
| 2015-05-06 | 3 | Halak Brian K | TBRA | Common Stock | D | 95.226 | ||||||||
| 2015-05-06 | 3 | Halak Brian K | TBRA | Common Stock | D | 95.226 | ||||||||
| 2015-05-06 | 3 | Halak Brian K | TBRA | Common Stock | D | 6.551.090 | ||||||||
| 2015-05-06 | 3 | Halak Brian K | TBRA | Common Stock | D | 6.551.090 | ||||||||
| 2015-05-06 | 3 | Halak Brian K | TBRA | Common Stock | D | 6.551.090 | ||||||||
| 2015-05-06 | 3 | Halak Brian K | TBRA | Common Stock | D | 6.551.090 | ||||||||
| 2015-05-06 | 3 | Halak Brian K | TBRA | Common Stock | D | 6.551.090 | ||||||||
| 2015-05-06 | 3 | Halak Brian K | TBRA | Common Stock | D | 6.551.090 | ||||||||
| 2015-05-06 | 3 | Halak Brian K | TBRA | Common Stock | D | 6.551.090 | ||||||||
| 2015-05-06 | 3 | Halak Brian K | TBRA | Common Stock | D | 6.551.090 | ||||||||
| 2015-05-06 | 2015-05-04 | 4 | Cooper Jeffrey H | TBRA | Stock Options (right to buy) | D | 8,13 | 13.539 | 13.539 | |||||
| 2015-05-06 | 2015-05-04 | 4 | Frazier Healthcare V, LP | TBRA | Common Stock | D | 2.668.570 | 2.668.570 | ||||||
| 2015-05-06 | 2015-05-04 | 4 | Heron Patrick J | TBRA | Stock Option (right to buy) | D | 2,96 | 4.332 | 4.332 | |||||
| 2015-05-06 | 2015-05-04 | 4 | Heron Patrick J By Frazier Healthcare V, LP | TBRA | Common Stock | I | 2.668.570 | 2.668.570 | ||||||
| 2015-05-06 | 2015-05-04 | 4 | DOMAIN PARTERS VII L P | TBRA | Common Stock | D | 10,6200 | 277.777 | 2.950 | 3.553.322 | ||||
| 2015-05-06 | 2015-05-04 | 4 | Fischer Laurent | TBRA | Stock Options (right to buy) | D | 4,81 | 503.882 | 672.671 | |||||
| 2015-05-06 | 2015-05-04 | 4 | Fischer Laurent | TBRA | Stock Options (right to buy) | D | 4,81 | 83.324 | 168.789 | |||||
| 2015-05-06 | 2015-05-04 | 4 | Fischer Laurent | TBRA | Stock Options (right to buy) | D | 3,51 | 6.769 | 85.465 | |||||
| 2015-05-06 | 2015-05-04 | 4 | Fischer Laurent | TBRA | Stock Options (right to buy) | D | 3,14 | 16.416 | 78.696 | |||||
| 2015-05-06 | 2015-05-04 | 4 | Fischer Laurent | TBRA | Stock Options (right to buy) | D | 3,14 | 53.616 | 62.280 | |||||
| 2015-05-06 | 2015-05-04 | 4 | Fischer Laurent | TBRA | Stock Options (right to buy) | D | 2,96 | 4.332 | 8.664 | |||||
| 2015-05-06 | 2015-05-04 | 4 | Fischer Laurent | TBRA | Stock Options (right to buy) | D | 3,14 | 4.332 | 8.664 | |||||
| 2015-05-06 | 2015-05-04 | 4 | Novo A/S | TBRA | COMMON STOCK | D | 10,6200 | 838.041 | 8.900 | 2.696.405 | ||||
| 2015-05-06 | 2015-05-04 | 4 | DOMAIN ASSOCIATES | TBRA | Common Stock | D | 36.187 | 38.094 | ||||||
| 2015-05-06 | 2015-05-04 | 4 | Brosgart Carol L | TBRA | Stock Options (right to buy) | D | 4,81 | 18.956 | 31.952 | |||||
| 2015-05-06 | 2015-05-04 | 4 | Brosgart Carol L | TBRA | Stock Options (right to buy) | D | 4,25 | 4.332 | 12.996 | |||||
| 2015-05-06 | 2015-05-04 | 4 | Brosgart Carol L | TBRA | Stock Options (right to buy) | D | 3,51 | 4.332 | 12.996 | |||||
| 2015-05-06 | 2015-05-04 | 4 | Brosgart Carol L | TBRA | Stock Options (right to buy) | D | 3,14 | 4.332 | 8.664 | |||||
| 2015-05-06 | 2015-05-04 | 4 | Jenkins Helen | TBRA | Stock Options (right to buy) | D | 4,81 | 29.841 | 75.700 | |||||
| 2015-05-06 | 2015-05-04 | 4 | Jenkins Helen | TBRA | Stock Options (right to buy) | D | 3,51 | 16.311 | 45.859 | |||||
| 2015-05-06 | 2015-05-04 | 4 | Jenkins Helen | TBRA | Stock Options (right to buy) | D | 3,51 | 29.548 | 29.548 | |||||
| 2015-05-06 | 2015-05-06 | 4 | Peetz Christopher | TBRA | Stock Options | D | 4,81 | 31.091 | 99.823 | |||||
| 2015-05-06 | 2015-05-06 | 4 | Peetz Christopher | TBRA | Stock Options (right to buy) | D | 4,81 | 68.732 | 68.732 | |||||
| 2015-05-06 | 2015-05-04 | 4 | Lefebvre Eric | TBRA | Stock Options (right to buy) | D | 3,51 | 21.607 | 100.894 | |||||
| 2015-05-06 | 2015-05-04 | 4 | Lefebvre Eric | TBRA | Stock Options (right to buy) | D | 3,51 | 79.287 | 79.287 | |||||
| 2015-05-06 | 2015-05-04 | 4 | Melincoff Gwen A | TBRA | Stock Options (right to buy) | D | 8,13 | 13.539 | 13.539 | |||||
| 2015-02-20 | 2014-12-03 | 4/A | Metzger Michael A | RGDO | Stock Option (right to buy) | D | 0,84 | 837.531 | 837.531 | |||||
| 2015-01-06 | 2015-01-01 | 4 | NEFF P SHERRILL | RGDO | Common Stock (right to buy) | D | 0,91 | 159.261 | 159.261 | |||||
| 2015-01-05 | 2015-01-01 | 4 | Clark B. Jefferson | RGDO | Common Stock (right to buy) | D | 0,91 | 159.261 | 159.261 | |||||
| 2015-01-05 | 2015-01-01 | 4 | Elsey R Don | RGDO | Common Stock (right to buy) | D | 0,91 | 92.902 | 92.902 | |||||
| 2015-01-05 | 2015-01-01 | 4 | Legault Pierre | RGDO | Common Stock (right to buy) | D | 0,91 | 159.261 | 159.261 | |||||
| 2015-01-05 | 2015-01-01 | 4 | Podlesak Dennis | RGDO | Common Stock (right to buy) | D | 0,91 | 159.261 | 159.261 | |||||
| 2015-01-05 | 2015-01-01 | 4 | Gopka Anton | RGDO | Common Stock (right to buy) | D | 0,91 | 159.261 | 159.261 | |||||
| 2015-01-05 | 2015-01-01 | 4 | Mendelsohn Michael | RGDO | Common Stock (right to buy) | D | 0,91 | 159.261 | 159.261 | |||||
| 2015-01-05 | 2015-01-01 | 4 | Fromkin Andrew J. | RGDO | Common Stock (right to buy) | D | 0,91 | 159.261 | 159.261 | |||||
| 2015-01-05 | 2015-01-01 | 4 | TREU JESSE I | RGDO | Stock Option (right to buy) | D | 0,91 | 159.261 | 159.261 | |||||
| 2014-12-24 | 2014-10-28 | 4 | KIERLIN ROBERT A | RGDO | Common Stock, par value $0.001 per share | D | 1,1000 | -941.252 | -1.035 | 3.214.955 | ||||
| 2014-12-24 | 2014-10-27 | 4 | KIERLIN ROBERT A | RGDO | Common Stock, par value $0.001 per share | D | 1,0800 | -18.748 | -20 | 4.156.207 | ||||
| 2014-12-24 | 2014-10-24 | 4 | KIERLIN ROBERT A | RGDO | Common Stock, par value $0.001 per share | D | 1,1000 | -100.000 | -110 | 4.174.955 | ||||
| 2014-12-24 | 2014-10-24 | 4 | KIERLIN ROBERT A | RGDO | Common Stock, par value $0.001 per share | D | 1,0600 | -10.000 | -11 | 4.274.955 | ||||
| 2014-12-05 | 2014-12-03 | 4 | Metzger Michael A | RGDO | Stock Option (right to buy) | D | 0,85 | 837.531 | 837.531 | |||||
| 2014-06-16 | 3 | Fromkin Andrew J. [by his children] | RGDO | Common Stock | I | 200 | ||||||||
| 2014-06-16 | 3 | Fromkin Andrew J. | RGDO | Common Stock | D | 250 | ||||||||
| 2014-06-16 | 3 | Fromkin Andrew J. | RGDO | Common Stock | D | 250 | ||||||||
| 2014-06-16 | 3 | Fromkin Andrew J. [by his children] | RGDO | Common Stock | I | 200 | ||||||||
| 2014-06-16 | 2014-06-12 | 4 | Fromkin Andrew J. | RGDO | Stock Option (right to buy) | D | 6,47 | 51.000 | 51.000 | |||||
| 2014-05-21 | 3 | Pelliccione Nicholas J. | RGDO | No securities are beneficially owned | D | 0 | ||||||||
| 2014-05-21 | 2014-05-21 | 4 | Pelliccione Nicholas J. | RGDO | Stock Option (right to buy) | D | 5,46 | 100.000 | 100.000 | |||||
| 2014-05-07 | 3 | Elsey R Don | RGDO | No securities are beneficially owned | D | 0 | ||||||||
| 2014-05-07 | 2014-05-05 | 4 | Elsey R Don | RGDO | Stock Option (right to buy) | D | 6,36 | 250.000 | 250.000 | |||||
| 2014-04-17 | 2014-04-16 | 4 | KIERLIN ROBERT A | RGDO | Common Stock, par value $0.001 per share | D | 6,0000 | 575.000 | 3.450 | 4.284.955 | ||||
| 2014-03-25 | 2014-03-21 | 4 | BVF PARTNERS L P/IL By Biotechnology Value Fund II, L.P. | RGDO | Preferred Stock, $0.001 per share | I | 5,00 | 2.632 | 2.632 | |||||
| 2014-03-25 | 2014-03-21 | 4 | BVF PARTNERS L P/IL By Biotechnology Value Fund, L.P. | RGDO | Preferred Stock, $0.001 per share | I | 5,00 | 4.577 | 4.577 | |||||
| 2014-03-25 | 2014-03-21 | 4 | BVF PARTNERS L P/IL By Biotechnology Value Fund II, L.P. | RGDO | Common Stock, $0.001 par value | I | -526.436 | 1.121.221 | ||||||
| 2014-03-25 | 2014-03-21 | 4 | BVF PARTNERS L P/IL By Biotechnology Value Fund, L.P. | RGDO | Common Stock, $0.001 par value | I | -915.345 | 1.979.670 | ||||||
| 2014-03-03 | 2014-02-20 | 4 | Clark B. Jefferson | RGDO | Stock Option (right to buy) | I | 3,34 | -1 | 0 | |||||
| 2014-03-03 | 2014-02-20 | 4 | Clark B. Jefferson | RGDO | Warrant (right to buy) | I | 0,17 | -1 | 0 | |||||
| 2014-03-03 | 2014-02-20 | 4 | Clark B. Jefferson | RGDO | Stock Option (right to buy) | I | 4,51 | -1 | 0 | |||||
| 2014-03-03 | 2014-02-20 | 4 | Clark B. Jefferson | RGDO | Stock Option (right to buy) | I | 4,51 | -1 | 0 | |||||
| 2014-03-03 | 2014-02-20 | 4 | Clark B. Jefferson | RGDO | Common Stock, par value $0.001 per share | I | 0,1700 | 4.491 | 1 | 1.130.133 | ||||
| 2014-03-03 | 2014-02-20 | 4 | Clark B. Jefferson | RGDO | Common Stock, par value $0.001 per share | I | 4,5100 | 3.341 | 15 | 1.125.642 | ||||
| 2014-03-03 | 2014-02-20 | 4 | Clark B. Jefferson | RGDO | Common Stock, par value $0.001 per share | I | 4,5100 | 5.447 | 25 | 1.122.301 | ||||
| 2014-03-03 | 2014-02-20 | 4 | Clark B. Jefferson | RGDO | Common Stock, par value $0.001 per share | I | 3,3400 | 2.095 | 7 | 1.116.854 | ||||
| 2014-02-10 | 3 | LAMPERT MARK N By Biotechnology Value Fund II, L.P. | RGDO | Common stock, $0.001 par value | I | 4.222.129 | ||||||||
| 2014-02-10 | 3 | LAMPERT MARK N By Biotechnology Value Fund, L.P. | RGDO | Common stock, $0.001 par value | I | 5.080.487 | ||||||||
| 2014-02-10 | 3 | LAMPERT MARK N By Biotechnology Value Fund II, L.P. | RGDO | Common stock, $0.001 par value | I | 4.222.129 | ||||||||
| 2014-02-10 | 3 | LAMPERT MARK N By Biotechnology Value Fund, L.P. | RGDO | Common stock, $0.001 par value | I | 5.080.487 | ||||||||
| 2014-02-10 | 3 | LAMPERT MARK N By Biotechnology Value Fund, L.P. | RGDO | Common stock, $0.001 par value | I | 5.080.487 | ||||||||
| 2014-02-10 | 3 | LAMPERT MARK N By Biotechnology Value Fund, L.P. | RGDO | Common stock, $0.001 par value | I | 5.080.487 | ||||||||
| 2014-02-10 | 3 | LAMPERT MARK N By Biotechnology Value Fund II, L.P. | RGDO | Common stock, $0.001 par value | I | 4.222.129 | ||||||||
| 2014-02-10 | 3 | LAMPERT MARK N By Biotechnology Value Fund II, L.P. | RGDO | Common stock, $0.001 par value | I | 4.222.129 | ||||||||
| 2014-02-10 | 3 | LAMPERT MARK N By Biotechnology Value Fund, L.P. | RGDO | Common stock, $0.001 par value | I | 5.080.487 | ||||||||
| 2014-02-10 | 3 | LAMPERT MARK N By Biotechnology Value Fund II, L.P. | RGDO | Common stock, $0.001 par value | I | 4.222.129 | ||||||||
| 2014-02-10 | 3 | LAMPERT MARK N By Biotechnology Value Fund II, L.P. | RGDO | Common stock, $0.001 par value | I | 4.222.129 | ||||||||
| 2014-02-10 | 3 | LAMPERT MARK N By Biotechnology Value Fund, L.P. | RGDO | Common stock, $0.001 par value | I | 5.080.487 | ||||||||
| 2014-02-06 | 2014-02-05 | 4 | KIERLIN ROBERT A | RGDO | Common Stock, par value $0.001 per share | D | 5,0000 | 400.000 | 2.000 | 3.700.955 | ||||
| 2014-01-03 | 2014-01-01 | 4 | TREU JESSE I | RGDO | Stock Option (right to buy) | D | 4,77 | 9.640 | 9.640 | |||||
| 2014-01-03 | 2014-01-01 | 4 | NEFF P SHERRILL | RGDO | Stock Option (right to buy) | D | 4,77 | 9.640 | 9.640 | |||||
| 2014-01-03 | 2014-01-01 | 4 | Legault Pierre | RGDO | Stock Option (right to buy) | D | 4,77 | 4.820 | 4.820 | |||||
| 2014-01-03 | 2014-01-01 | 4 | Podlesak Dennis | RGDO | Stock Option (right to buy) | D | 4,77 | 9.640 | 9.640 | |||||
| 2014-01-03 | 2014-01-01 | 4 | Mazzo David J | RGDO | Stock Option (right to buy) | D | 4,77 | 180.000 | 180.000 | |||||
| 2014-01-03 | 2014-01-01 | 4 | Clark B. Jefferson | RGDO | Stock Option (right to buy) | D | 4,77 | 9.640 | 9.640 | |||||
| 2014-01-03 | 2014-01-01 | 4 | Rusconi Christopher Paul | RGDO | Stock Option (right to buy) | D | 4,77 | 73.000 | 73.000 | |||||
| 2014-01-03 | 2014-01-01 | 4 | Gopka Anton | RGDO | Stock Option (right to buy) | D | 4,77 | 9.640 | 9.640 | |||||
| 2014-01-03 | 2014-01-01 | 4 | Wisniewski Raphael | RGDO | Stock Option (right to buy) | D | 4,77 | 9.640 | 9.640 | |||||
| 2014-01-03 | 2014-01-01 | 4 | Courts Christopher | RGDO | Stock Option (right to buy) | D | 4,77 | 23.000 | 23.000 | |||||
| 2014-01-03 | 2014-01-01 | 4 | Zelenkofske Steven | RGDO | Stock Option (right to buy) | D | 4,77 | 75.000 | 75.000 | |||||
| 2014-01-03 | 2014-01-01 | 4 | Giaquinto Alexander R | RGDO | Stock Option (right to buy) | D | 4,77 | 38.000 | 38.000 | |||||
| 2014-01-03 | 2014-01-01 | 4 | Mendelsohn Michael | RGDO | Stock Option (right to buy) | D | 4,77 | 4.820 | 4.820 | |||||
| 2013-12-20 | 2013-12-16 | 4 | Metzger Michael A | RGDO | Stock Option (right to buy) | D | 4,81 | 434.008 | 434.008 | |||||
| 2013-08-30 | 2013-08-27 | 4/A | RMI Investments S.a.r.l. | RGDO | Series E Preferred Stock | D | -22.878.805 | 0 | ||||||
| 2013-08-30 | 2013-08-27 | 4/A | RMI Investments S.a.r.l. | RGDO | Common Stock, par value $0.001 per share | D | 4,0000 | 3.866.529 | 15.466 | 5.236.517 | ||||
| 2013-08-30 | 2013-08-27 | 4/A | RMI Investments S.a.r.l. | RGDO | Common Stock, par value $0.001 per share | D | 1.369.988 | 1.369.988 | ||||||
| 2013-08-29 | 2013-08-27 | 4 | QUAKER BIO VENTURES LP | RGDO | Series E Preferred Stock | D | -807.652 | 0 | ||||||
| 2013-08-29 | 2013-08-27 | 4 | QUAKER BIO VENTURES LP | RGDO | Series D Preferred Stock | D | -7.769.715 | 0 | ||||||
| 2013-08-29 | 2013-08-27 | 4 | QUAKER BIO VENTURES LP | RGDO | Series C Preferred Stock | D | -4.566.908 | 0 | ||||||
| 2013-08-29 | 2013-08-27 | 4 | QUAKER BIO VENTURES LP | RGDO | Series B Preferred Stock | D | -6.666.667 | 0 | ||||||
| 2013-08-29 | 2013-08-27 | 4 | QUAKER BIO VENTURES LP | RGDO | Common Stock, par value $0.001 per share | D | 4,0000 | 71.810 | 287 | 1.294.021 | ||||
| 2013-08-29 | 2013-08-27 | 4 | QUAKER BIO VENTURES LP | RGDO | Common Stock, par value $0.001 per share | D | 48.362 | 1.222.211 | ||||||
| 2013-08-29 | 2013-08-27 | 4 | QUAKER BIO VENTURES LP | RGDO | Common Stock, par value $0.001 per share | D | 465.252 | 1.173.849 | ||||||
| 2013-08-29 | 2013-08-27 | 4 | QUAKER BIO VENTURES LP | RGDO | Common Stock, par value $0.001 per share | D | 273.468 | 708.597 | ||||||
| 2013-08-29 | 2013-08-27 | 4 | QUAKER BIO VENTURES LP | RGDO | Common Stock, par value $0.001 per share | D | 399.201 | 435.129 | ||||||
| 2013-08-29 | 2013-08-27 | 4 | NEFF P SHERRILL See Footnote 6 | RGDO | Series E Preferred Stock | I | -807.652 | 0 | ||||||
| 2013-08-29 | 2013-08-27 | 4 | NEFF P SHERRILL See Footnote 6 | RGDO | Series D Preferred Stock | I | -7.769.715 | 0 | ||||||
| 2013-08-29 | 2013-08-27 | 4 | NEFF P SHERRILL See Footnote 6 | RGDO | Series C Preferred Stock | I | -4.566.908 | 0 | ||||||
| 2013-08-29 | 2013-08-27 | 4 | NEFF P SHERRILL See Footnote 6 | RGDO | Series B Preferred Stock | I | -6.666.667 | 0 | ||||||
| 2013-08-29 | 2013-08-27 | 4 | NEFF P SHERRILL | RGDO | Stock Option (right to buy) | D | 4,00 | 17.964 | 17.964 | |||||
| 2013-08-29 | 2013-08-27 | 4 | NEFF P SHERRILL See Footnote 6 | RGDO | Common Stock, par value $0.001 per share | I | 4,0000 | 71.810 | 287 | 1.294.021 | ||||
| 2013-08-29 | 2013-08-27 | 4 | NEFF P SHERRILL See Footnote 6 | RGDO | Common Stock, par value $0.001 per share | I | 48.362 | 1.222.211 | ||||||
| 2013-08-29 | 2013-08-27 | 4 | NEFF P SHERRILL See Footnote 6 | RGDO | Common Stock, par value $0.001 per share | I | 465.252 | 1.173.849 | ||||||
| 2013-08-29 | 2013-08-27 | 4 | NEFF P SHERRILL See Footnote 6 | RGDO | Common Stock, par value $0.001 per share | I | 273.468 | 708.597 | ||||||
| 2013-08-29 | 2013-08-27 | 4 | NEFF P SHERRILL See Footnote 6 | RGDO | Common Stock, par value $0.001 per share | I | 399.201 | 435.129 | ||||||
| 2013-08-29 | 2013-08-27 | 4 | Podlesak Dennis | RGDO | Stock Option (right to buy) | D | 4,00 | 366.605 | 366.605 | |||||
| 2013-08-29 | 2013-08-27 | 4 | Mazzo David J | RGDO | Stock Option (right to buy) | D | 4,00 | 558.167 | 558.167 | |||||
| 2013-08-29 | 2013-08-27 | 4 | McDonald Ellen | RGDO | Stock Option (right to buy) | D | 4,00 | 51.092 | 51.092 | |||||
| 2013-08-29 | 2013-08-27 | 4 | Clark B. Jefferson See Footnote 7 | RGDO | Series E Preferred Stock | I | -807.652 | 0 | ||||||
| 2013-08-29 | 2013-08-27 | 4 | Clark B. Jefferson See Footnote 7 | RGDO | Series D Preferred Stock | I | 5.376.964 | 0 | ||||||
| 2013-08-29 | 2013-08-27 | 4 | Clark B. Jefferson See Footnote 7 | RGDO | Series C Preferred Stock | I | -2.222.222 | 0 | ||||||
| 2013-08-29 | 2013-08-27 | 4 | Clark B. Jefferson See Footnote 7 | RGDO | Series B Preferred Stock | I | -1.458.333 | 0 | ||||||
| 2013-08-29 | 2013-08-27 | 4 | Clark B. Jefferson See Footnote 7 | RGDO | Series A Preferred Stock | I | -2.428.367 | 0 | ||||||
| 2013-08-29 | 2013-08-27 | 4 | Clark B. Jefferson | RGDO | Stock Option (right to buy) | D | 4,00 | 17.964 | 17.964 | |||||
| 2013-08-29 | 2013-08-27 | 4 | Clark B. Jefferson See Footnote 8 | RGDO | Common Stock, par value $0.001 per share | I | 4,0000 | 359.310 | 1.437 | 1.114.759 | ||||
| 2013-08-29 | 2013-08-27 | 4 | Clark B. Jefferson See Footnote 7 | RGDO | Common Stock, par value $0.001 per share | I | 48.362 | 755.449 | ||||||
| 2013-08-29 | 2013-08-27 | 4 | Clark B. Jefferson See Footnote 7 | RGDO | Common Stock, par value $0.001 per share | I | 321.973 | 707.087 | ||||||
| 2013-08-29 | 2013-08-27 | 4 | Clark B. Jefferson See Footnote 7 | RGDO | Common Stock, par value $0.001 per share | I | 133.067 | 385.114 | ||||||
| 2013-08-29 | 2013-08-27 | 4 | Clark B. Jefferson See Footnote 7 | RGDO | Common Stock, par value $0.001 per share | I | 87.325 | 252.047 | ||||||
| 2013-08-29 | 2013-08-27 | 4 | Clark B. Jefferson See Footnote 7 | RGDO | Common Stock, par value $0.001 per share | I | 145.411 | 164.722 | ||||||
| 2013-08-29 | 2023-08-27 | 4 | Wisniewski Raphael | RGDO | Stock Option (right to buy) | D | 4,00 | 17.964 | 17.964 | |||||
| 2013-08-29 | 2013-08-27 | 4 | Wisniewski Raphael See Footnote 4 | RGDO | Series E Preferred Stock | I | -2.832.872 | 0 | ||||||
| 2013-08-29 | 2013-08-27 | 4 | Wisniewski Raphael See Footnote 4 | RGDO | Series D Preferred Stock | I | -17.066.243 | 0 | ||||||
| 2013-08-29 | 2013-08-27 | 4 | Wisniewski Raphael See Footnote 4 | RGDO | Common Stock, par value $0.001 per share | I | 4,0000 | 1.215.708 | 4.863 | 2.407.271 | ||||
| 2013-08-29 | 2013-08-27 | 4 | Wisniewski Raphael See Footnote 4 | RGDO | Common Stock, par value $0.001 per share | I | 169.633 | 1.191.563 | ||||||
| 2013-08-29 | 2013-08-27 | 4 | Wisniewski Raphael See Footnote 4 | RGDO | Common Stock, par value $0.001 per share | I | 1.021.930 | 1.021.930 | ||||||
| 2013-08-29 | 2013-08-27 | 4 | Giaquinto Alexander R | RGDO | Stock Option (right to buy) | D | 4,00 | 29.929 | 29.929 | |||||
| 2013-08-29 | 2013-08-27 | 4 | Zelenkofske Steven | RGDO | Stock Option (right to buy) | D | 4,00 | 225.552 | 225.552 | |||||
| 2013-08-29 | 2013-08-27 | 4 | Courts Christopher | RGDO | Series E Preferred Stock | D | -90.277 | 0 | ||||||
| 2013-08-29 | 2013-08-27 | 4 | Courts Christopher | RGDO | Stock Option (right to buy) | D | 4,00 | 25.965 | 25.965 | |||||
| 2013-08-29 | 2013-08-27 | 4 | Courts Christopher | RGDO | Common Stock, par value $0.001 per share | D | 5.405 | 5.405 | ||||||
| 2013-08-29 | 2013-08-27 | 4 | Rusconi Christopher Paul | RGDO | Stock Option (right to buy) | D | 4,00 | 59.880 | 59.880 | |||||
| 2013-08-29 | 2013-08-27 | 4 | Gopka Anton See Footnote 3 | RGDO | Series E Preferred Stock | I | -22.878.805 | 0 | ||||||
| 2013-08-29 | 2013-08-27 | 4 | Gopka Anton | RGDO | Stock Option (right to buy) | D | 4,00 | 17.964 | 17.964 | |||||
| 2013-08-29 | 2013-08-27 | 4 | Gopka Anton See Footnote 3 | RGDO | Common Stock, par value $0.001 per share | I | 4,0000 | 3.866.529 | 15.466 | 5.236.517 | ||||
| 2013-08-29 | 2013-08-27 | 4 | Gopka Anton See Footnote 3 | RGDO | Common Stock, par value $0.001 per share | I | 1.369.988 | 1.369.988 | ||||||
| 2013-08-29 | 2013-08-27 | 4 | BIODISCOVERY 3, FCPR | RGDO | Series E Preferred Stock | D | -2.832.872 | 0 | ||||||
| 2013-08-29 | 2013-08-27 | 4 | BIODISCOVERY 3, FCPR | RGDO | Series D Preferred Stock | D | -17.066.243 | 0 | ||||||
| 2013-08-29 | 2013-08-27 | 4 | BIODISCOVERY 3, FCPR | RGDO | Common Stock, par value $0.001 per share | D | 4,0000 | 1.215.708 | 4.863 | 2.407.271 | ||||
| 2013-08-29 | 2013-08-27 | 4 | BIODISCOVERY 3, FCPR | RGDO | Common Stock, par value $0.001 per share | D | 169.633 | 1.191.563 | ||||||
| 2013-08-29 | 2013-08-27 | 4 | BIODISCOVERY 3, FCPR | RGDO | Common Stock, par value $0.001 per share | D | 1.021.930 | 1.021.930 | ||||||
| 2013-08-29 | 2013-08-27 | 4 | RMI Investments S.a.r.l. | RGDO | Series E Preferred Stock | D | -22.878.805 | 0 | ||||||
| 2013-08-29 | 2013-08-27 | 4 | RMI Investments S.a.r.l. | RGDO | Common Stock, par value $0.001 per share | D | 4,0000 | 3.866.529 | 15.466 | 5.236.517 | ||||
| 2013-08-29 | 2013-08-27 | 4 | RMI Investments S.a.r.l. | RGDO | Common Stock, par value $0.001 per share | D | 1.369.988 | 1.369.988 | ||||||
| 2013-08-29 | 2013-08-27 | 4 | KIERLIN ROBERT A | RGDO | Series E Preferred Stock | D | -10.750.105 | 0 | ||||||
| 2013-08-29 | 2013-08-27 | 4 | KIERLIN ROBERT A | RGDO | Series D Preferred Stock | D | -23.261.013 | 0 | ||||||
| 2013-08-29 | 2013-08-27 | 4 | KIERLIN ROBERT A | RGDO | Series C Preferred Stock | D | -3.324.136 | 0 | ||||||
| 2013-08-29 | 2013-08-27 | 4 | KIERLIN ROBERT A | RGDO | Series B Preferred Stock | D | -1.670.833 | 0 | ||||||
| 2013-08-29 | 2013-08-27 | 4 | KIERLIN ROBERT A | RGDO | Series A Preferred Stock | D | -3.369.811 | 0 | ||||||
| 2013-08-29 | 2013-08-27 | 4 | KIERLIN ROBERT A | RGDO | Common Stock, par value $0.001 per share | D | 4,0000 | 750.000 | 3.000 | 3.300.955 | ||||
| 2013-08-29 | 2013-08-27 | 4 | KIERLIN ROBERT A | RGDO | Common Stock, par value $0.001 per share | D | 634.718 | 2.550.955 | ||||||
| 2013-08-29 | 2013-08-27 | 4 | KIERLIN ROBERT A | RGDO | Common Stock, par value $0.001 per share | D | 1.392.875 | 1.916.237 | ||||||
| 2013-08-29 | 2013-08-27 | 4 | KIERLIN ROBERT A | RGDO | Common Stock, par value $0.001 per share | D | 199.050 | 523.362 | ||||||
| 2013-08-29 | 2013-08-27 | 4 | KIERLIN ROBERT A | RGDO | Common Stock, par value $0.001 per share | D | 100.050 | 324.312 | ||||||
| 2013-08-29 | 2013-08-27 | 4 | KIERLIN ROBERT A | RGDO | Common Stock, par value $0.001 per share | D | 201.785 | 224.262 | ||||||
| 2013-08-28 | 2013-08-27 | 4 | Domain Partners VI, L.P. | RGDO | Series E Preferred Stock | D | -225.913 | 0 | ||||||
| 2013-08-28 | 2013-08-27 | 4 | Domain Partners VI, L.P. | RGDO | Series D Preferred Stock | D | -894.120 | 0 | ||||||
| 2013-08-28 | 2013-08-27 | 4 | Domain Partners VI, L.P. | RGDO | Series C Preferred Stock | D | -270.568 | 0 | ||||||
| 2013-08-28 | 2013-08-27 | 4 | Domain Partners VI, L.P. | RGDO | Series B Preferred Stock | D | -394.969 | 0 | ||||||
| 2013-08-28 | 2013-08-27 | 4 | Domain Partners VI, L.P. | RGDO | Common Stock | D | 4,0000 | 750.000 | 3.000 | 2.571.117 | ||||
| 2013-08-28 | 2013-08-27 | 4 | Domain Partners VI, L.P. | RGDO | Common Stock | D | 225.913 | 1.821.117 | ||||||
| 2013-08-28 | 2013-08-27 | 4 | Domain Partners VI, L.P. | RGDO | Common Stock | D | 894.120 | 1.595.204 | ||||||
| 2013-08-28 | 2013-08-27 | 4 | Domain Partners VI, L.P. | RGDO | Common Stock | D | 270.568 | 701.084 | ||||||
| 2013-08-28 | 2013-08-27 | 4 | Domain Partners VI, L.P. | RGDO | Common Stock | D | 394.969 | 430.516 | ||||||
| 2013-08-28 | 2013-08-27 | 4 | DP VI Associates, L.P. | RGDO | Series D Preferred Stock | D | -7.407 | 0 | ||||||
| 2013-08-28 | 2013-08-27 | 4 | DP VI Associates, L.P. | RGDO | Series C Preferred Stock | D | -2.899 | 0 | ||||||
| 2013-08-28 | 2013-08-27 | 4 | DP VI Associates, L.P. | RGDO | Series B Preferred Stock | D | -4.233 | 0 | ||||||
| 2013-08-28 | 2013-08-27 | 4 | DP VI Associates, L.P. | RGDO | Common Stock | D | 7.407 | 14.920 | ||||||
| 2013-08-28 | 2013-08-27 | 4 | DP VI Associates, L.P. | RGDO | Common Stock | D | 2.899 | 7.513 | ||||||
| 2013-08-28 | 2013-08-27 | 4 | DP VI Associates, L.P. | RGDO | Common Stock | D | 4.233 | 4.614 | ||||||
| 2013-08-28 | 2013-08-27 | 4 | BLAIR JAMES C By DP VI Associates, L.P. | RGDO | Series D Preferred Stock | I | -7.407 | 0 | ||||||
| 2013-08-28 | 2013-08-27 | 4 | BLAIR JAMES C By DP VI Associates, L.P. | RGDO | Series C Preferred Stock | I | -2.899 | 0 | ||||||
| 2013-08-28 | 2013-08-27 | 4 | BLAIR JAMES C By DP VI Associates, L.P. | RGDO | Series B Preferred Stock | I | -4.233 | 0 | ||||||
| 2013-08-28 | 2013-08-27 | 4 | BLAIR JAMES C By Domain Partners VI, L.P. | RGDO | Series E Preferred Stock | I | -225.913 | 0 | ||||||
| 2013-08-28 | 2013-08-27 | 4 | BLAIR JAMES C By Domain Partners VI, L.P. | RGDO | Series D Preferred Stock | I | -894.120 | 0 | ||||||
| 2013-08-28 | 2013-08-27 | 4 | BLAIR JAMES C By Domain Partners VI, L.P. | RGDO | Series C Preferred Stock | I | -270.568 | 0 | ||||||
| 2013-08-28 | 2013-08-27 | 4 | BLAIR JAMES C By Domain Partners VI, L.P. | RGDO | Series B Preferred Stock | I | -394.969 | 0 | ||||||
| 2013-08-28 | 2013-08-27 | 4 | BLAIR JAMES C By DP VI Associates, L.P. | RGDO | Common Stock | I | 7.407 | 14.920 | ||||||
| 2013-08-28 | 2013-08-27 | 4 | BLAIR JAMES C By DP VI Associates, L.P. | RGDO | Common Stock | I | 2.899 | 7.513 | ||||||
| 2013-08-28 | 2013-08-27 | 4 | BLAIR JAMES C By DP VI Associates, L.P. | RGDO | Common Stock | I | 4.233 | 4.614 | ||||||
| 2013-08-28 | 2013-08-27 | 4 | BLAIR JAMES C By Domain Partners VI, L.P. | RGDO | Common Stock | I | 4,0000 | 750.000 | 3.000 | 2.571.117 | ||||
| 2013-08-28 | 2013-08-27 | 4 | BLAIR JAMES C By Domain Partners VI, L.P. | RGDO | Common Stock | I | 225.913 | 1.821.117 | ||||||
| 2013-08-28 | 2013-08-27 | 4 | BLAIR JAMES C By Domain Partners VI, L.P. | RGDO | Common Stock | I | 894.120 | 1.595.204 | ||||||
| 2013-08-28 | 2013-08-27 | 4 | BLAIR JAMES C By Domain Partners VI, L.P. | RGDO | Common Stock | I | 270.568 | 701.084 | ||||||
| 2013-08-28 | 2013-08-27 | 4 | BLAIR JAMES C By Domain Partners VI, L.P. | RGDO | Common Stock | I | 394.969 | 430.516 | ||||||
| 2013-08-28 | 2013-08-27 | 4 | DOVEY BRIAN H By DP VI Associates, L.P. | RGDO | Series D Preferred Stock | I | -7.407 | 0 | ||||||
| 2013-08-28 | 2013-08-27 | 4 | DOVEY BRIAN H By DP VI Associates, L.P. | RGDO | Series C Preferred Stock | I | -2.899 | 0 | ||||||
| 2013-08-28 | 2013-08-27 | 4 | DOVEY BRIAN H By DP VI Associates, L.P. | RGDO | Series B Preferred Stock | I | -4.233 | 0 | ||||||
| 2013-08-28 | 2013-08-27 | 4 | DOVEY BRIAN H By Domain Partners VI, L.P. | RGDO | Series E Preferred Stock | I | -225.913 | 0 | ||||||
| 2013-08-28 | 2013-08-27 | 4 | DOVEY BRIAN H By Domain Partners VI, L.P. | RGDO | Series D Preferred Stock | I | -894.120 | 0 | ||||||
| 2013-08-28 | 2013-08-27 | 4 | DOVEY BRIAN H By Domain Partners VI, L.P. | RGDO | Series C Preferred Stock | I | -270.568 | 0 | ||||||
| 2013-08-28 | 2013-08-27 | 4 | DOVEY BRIAN H By Domain Partners VI, L.P. | RGDO | Series B Preferred Stock | I | -394.969 | 0 | ||||||
| 2013-08-28 | 2013-08-27 | 4 | DOVEY BRIAN H By DP VI Associates, L.P. | RGDO | Common Stock | I | 7.407 | 14.920 | ||||||
| 2013-08-28 | 2013-08-27 | 4 | DOVEY BRIAN H By DP VI Associates, L.P. | RGDO | Common Stock | I | 2.899 | 7.513 | ||||||
| 2013-08-28 | 2013-08-27 | 4 | DOVEY BRIAN H By DP VI Associates, L.P. | RGDO | Common Stock | I | 4.233 | 4.614 | ||||||
| 2013-08-28 | 2013-08-27 | 4 | DOVEY BRIAN H By Domain Partners VI, L.P. | RGDO | Common Stock | I | 4,0000 | 750.000 | 3.000 | 2.571.117 | ||||
| 2013-08-28 | 2013-08-27 | 4 | DOVEY BRIAN H By Domain Partners VI, L.P. | RGDO | Common Stock | I | 225.913 | 1.821.117 | ||||||
| 2013-08-28 | 2013-08-27 | 4 | DOVEY BRIAN H By Domain Partners VI, L.P. | RGDO | Common Stock | I | 894.120 | 1.595.204 | ||||||
| 2013-08-28 | 2013-08-27 | 4 | DOVEY BRIAN H By Domain Partners VI, L.P. | RGDO | Common Stock | I | 270.568 | 701.084 | ||||||
| 2013-08-28 | 2013-08-27 | 4 | DOVEY BRIAN H By Domain Partners VI, L.P. | RGDO | Common Stock | I | 394.969 | 430.516 | ||||||
| 2013-08-28 | 2013-08-27 | 4 | SCHOEMAKER KATHLEEN K By DP VI Associates, L.P. | RGDO | Series D Preferred Stock | I | -7.407 | 0 | ||||||
| 2013-08-28 | 2013-08-27 | 4 | SCHOEMAKER KATHLEEN K By DP VI Associates, L.P. | RGDO | Series C Preferred Stock | I | -2.899 | 0 | ||||||
| 2013-08-28 | 2013-08-27 | 4 | SCHOEMAKER KATHLEEN K By DP VI Associates, L.P. | RGDO | Series B Preferred Stock | I | -4.233 | 0 | ||||||
| 2013-08-28 | 2013-08-27 | 4 | SCHOEMAKER KATHLEEN K By Domain Partners VI, L.P. | RGDO | Series E Preferred Stock | I | -225.913 | 0 | ||||||
| 2013-08-28 | 2013-08-27 | 4 | SCHOEMAKER KATHLEEN K By Domain Partners VI, L.P. | RGDO | Series D Preferred Stock | I | -894.120 | 0 | ||||||
| 2013-08-28 | 2013-08-27 | 4 | SCHOEMAKER KATHLEEN K By Domain Partners VI, L.P. | RGDO | Series C Preferred Stock | I | -270.568 | 0 | ||||||
| 2013-08-28 | 2013-08-27 | 4 | SCHOEMAKER KATHLEEN K By Domain Partners VI, L.P. | RGDO | Series B Preferred Stock | I | -394.969 | 0 | ||||||
| 2013-08-28 | 2013-08-27 | 4 | SCHOEMAKER KATHLEEN K By DP VI Associates, L.P. | RGDO | Common Stock | I | 7.407 | 14.920 | ||||||
| 2013-08-28 | 2013-08-27 | 4 | SCHOEMAKER KATHLEEN K By DP VI Associates, L.P. | RGDO | Common Stock | I | 2.899 | 7.513 | ||||||
| 2013-08-28 | 2013-08-27 | 4 | SCHOEMAKER KATHLEEN K By DP VI Associates, L.P. | RGDO | Common Stock | I | 4.233 | 4.614 | ||||||
| 2013-08-28 | 2013-08-27 | 4 | SCHOEMAKER KATHLEEN K By Domain Partners VI, L.P. | RGDO | Common Stock | I | 4,0000 | 750.000 | 3.000 | 2.571.117 | ||||
| 2013-08-28 | 2013-08-27 | 4 | SCHOEMAKER KATHLEEN K By Domain Partners VI, L.P. | RGDO | Common Stock | I | 225.913 | 1.821.117 | ||||||
| 2013-08-28 | 2013-08-27 | 4 | SCHOEMAKER KATHLEEN K By Domain Partners VI, L.P. | RGDO | Common Stock | I | 894.120 | 1.595.204 | ||||||
| 2013-08-28 | 2013-08-27 | 4 | SCHOEMAKER KATHLEEN K By Domain Partners VI, L.P. | RGDO | Common Stock | I | 270.568 | 701.084 | ||||||
| 2013-08-28 | 2013-08-27 | 4 | SCHOEMAKER KATHLEEN K By Domain Partners VI, L.P. | RGDO | Common Stock | I | 394.969 | 430.516 | ||||||
| 2013-08-28 | 2013-08-27 | 4 | TREU JESSE I | RGDO | Stock Option (right to buy) | D | 4,00 | 17.964 | 17.964 | |||||
| 2013-08-28 | 2013-08-27 | 4 | TREU JESSE I By DP VI Associates, L.P. | RGDO | Series D Preferred Stock | I | -7.407 | 0 | ||||||
| 2013-08-28 | 2013-08-27 | 4 | TREU JESSE I By DP VI Associates, L.P. | RGDO | Series C Preferred Stock | I | -2.899 | 0 | ||||||
| 2013-08-28 | 2013-08-27 | 4 | TREU JESSE I By DP VI Associates, L.P. | RGDO | Series B Preferred Stock | I | -4.233 | 0 | ||||||
| 2013-08-28 | 2013-08-27 | 4 | TREU JESSE I By Domain Partners VI, L.P. | RGDO | Series E Preferred Stock | I | -225.913 | 0 | ||||||
| 2013-08-28 | 2013-08-27 | 4 | TREU JESSE I By Domain Partners VI, L.P. | RGDO | Series D Preferred Stock | I | -894.120 | 0 | ||||||
| 2013-08-28 | 2013-08-27 | 4 | TREU JESSE I By Domain Partners VI, L.P. | RGDO | Series C Preferred Stock | I | -270.568 | 0 | ||||||
| 2013-08-28 | 2013-08-27 | 4 | TREU JESSE I By Domain Partners VI, L.P. | RGDO | Series B Preferred Stock | I | -394.969 | 0 | ||||||
| 2013-08-28 | 2013-08-27 | 4 | TREU JESSE I By DP VI Associates, L.P. | RGDO | Common Stock | I | 7.407 | 14.920 | ||||||
| 2013-08-28 | 2013-08-27 | 4 | TREU JESSE I By DP VI Associates, L.P. | RGDO | Common Stock | I | 2.899 | 7.513 | ||||||
| 2013-08-28 | 2013-08-27 | 4 | TREU JESSE I By DP VI Associates, L.P. | RGDO | Common Stock | I | 4.233 | 4.614 | ||||||
| 2013-08-28 | 2013-08-27 | 4 | TREU JESSE I By Domain Partners VI, L.P. | RGDO | Common Stock | I | 4,0000 | 750.000 | 3.000 | 2.571.117 | ||||
| 2013-08-28 | 2013-08-27 | 4 | TREU JESSE I By Domain Partners VI, L.P. | RGDO | Common Stock | I | 225.913 | 1.821.117 | ||||||
| 2013-08-28 | 2013-08-27 | 4 | TREU JESSE I By Domain Partners VI, L.P. | RGDO | Common Stock | I | 894.120 | 1.595.204 | ||||||
| 2013-08-28 | 2013-08-27 | 4 | TREU JESSE I By Domain Partners VI, L.P. | RGDO | Common Stock | I | 270.568 | 701.084 | ||||||
| 2013-08-28 | 2013-08-27 | 4 | TREU JESSE I By Domain Partners VI, L.P. | RGDO | Common Stock | I | 394.969 | 430.516 | ||||||
| 2013-08-28 | 2013-08-27 | 4 | VITULLO NICOLE By DP VI Associates, L.P. | RGDO | Series D Preferred Stock | I | -7.407 | 0 | ||||||
| 2013-08-28 | 2013-08-27 | 4 | VITULLO NICOLE By DP VI Associates, L.P. | RGDO | Series C Preferred Stock | I | -2.899 | 0 | ||||||
| 2013-08-28 | 2013-08-27 | 4 | VITULLO NICOLE By DP VI Associates, L.P. | RGDO | Series B Preferred Stock | I | -4.233 | 0 | ||||||
| 2013-08-28 | 2013-08-27 | 4 | VITULLO NICOLE By Domain Partners VI, L.P. | RGDO | Series E Preferred Stock | I | -225.913 | 0 | ||||||
| 2013-08-28 | 2013-08-27 | 4 | VITULLO NICOLE By Domain Partners VI, L.P. | RGDO | Series D Preferred Stock | I | -894.120 | 0 | ||||||
| 2013-08-28 | 2013-08-27 | 4 | VITULLO NICOLE By Domain Partners VI, L.P. | RGDO | Series C Preferred Stock | I | -270.568 | 0 | ||||||
| 2013-08-28 | 2013-08-27 | 4 | VITULLO NICOLE By Domain Partners VI, L.P. | RGDO | Series B Preferred Stock | I | -394.969 | 0 | ||||||
| 2013-08-28 | 2013-08-27 | 4 | VITULLO NICOLE By DP VI Associates, L.P. | RGDO | Common Stock | I | 7.407 | 14.920 | ||||||
| 2013-08-28 | 2013-08-27 | 4 | VITULLO NICOLE By DP VI Associates, L.P. | RGDO | Common Stock | I | 2.899 | 7.513 | ||||||
| 2013-08-28 | 2013-08-27 | 4 | VITULLO NICOLE By DP VI Associates, L.P. | RGDO | Common Stock | I | 4.233 | 4.614 | ||||||
| 2013-08-28 | 2013-08-27 | 4 | VITULLO NICOLE By Domain Partners VI, L.P. | RGDO | Common Stock | I | 4,0000 | 750.000 | 3.000 | 2.571.117 | ||||
| 2013-08-28 | 2013-08-27 | 4 | VITULLO NICOLE By Domain Partners VI, L.P. | RGDO | Common Stock | I | 225.913 | 1.821.117 | ||||||
| 2013-08-28 | 2013-08-27 | 4 | VITULLO NICOLE By Domain Partners VI, L.P. | RGDO | Common Stock | I | 894.120 | 1.595.204 | ||||||
| 2013-08-28 | 2013-08-27 | 4 | VITULLO NICOLE By Domain Partners VI, L.P. | RGDO | Common Stock | I | 270.568 | 701.084 | ||||||
| 2013-08-28 | 2013-08-27 | 4 | VITULLO NICOLE By Domain Partners VI, L.P. | RGDO | Common Stock | I | 394.969 | 430.516 | ||||||
| 2013-08-21 | 3 | BLAIR JAMES C By Domain Associates, LLC | RGDO | Common Stock | I | 17.171 | ||||||||
| 2013-08-21 | 3 | BLAIR JAMES C By DP VI Associates, L.P. | RGDO | Common Stock | I | 381 | ||||||||
| 2013-08-21 | 3 | BLAIR JAMES C By Domain Partners VI, L.P. | RGDO | Common Stock | I | 35.547 | ||||||||
| 2013-08-21 | 3 | DOMAIN ASSOCIATES | RGDO | Common Stock | D | 17.171 | ||||||||
| 2013-08-21 | 3 | DOVEY BRIAN H By DP VI Associates, L.P. | RGDO | Common Stock | I | 381 | ||||||||
| 2013-08-21 | 3 | DOVEY BRIAN H By Domain Partners VI, L.P. | RGDO | Common Stock | I | 35.547 | ||||||||
| 2013-08-21 | 3 | DOVEY BRIAN H By Domain Associates, LLC | RGDO | Common Stock | I | 17.171 | ||||||||
| 2013-08-21 | 3 | Domain Partners VI, L.P. | RGDO | Common Stock | D | 35.547 | ||||||||
| 2013-08-21 | 3 | DP VI Associates, L.P. | RGDO | Common Stock | D | 381 | ||||||||
| 2013-08-21 | 3 | SCHOEMAKER KATHLEEN K By Domain Partners VI, L.P. | RGDO | Common Stock | I | 35.547 | ||||||||
| 2013-08-21 | 3 | SCHOEMAKER KATHLEEN K By DP VI Associates, L.P. | RGDO | Common Stock | I | 381 | ||||||||
| 2013-08-21 | 3 | SCHOEMAKER KATHLEEN K By Domain Associates, LLC | RGDO | Common Stock | I | 17.171 | ||||||||
| 2013-08-21 | 3 | TREU JESSE I By Domain Partners VI, L.P. | RGDO | Common Stock | I | 35.547 | ||||||||
| 2013-08-21 | 3 | TREU JESSE I By DP VI Associates, L.P. | RGDO | Common Stock | I | 381 | ||||||||
| 2013-08-21 | 3 | TREU JESSE I By Domain Associates, LLC | RGDO | Common Stock | I | 17.171 | ||||||||
| 2013-08-21 | 3 | VITULLO NICOLE By DP VI Associates, L.P. | RGDO | Common Stock | I | 381 | ||||||||
| 2013-08-21 | 3 | VITULLO NICOLE By Domain Associates, LLC | RGDO | Common Stock | I | 17.171 | ||||||||
| 2013-08-21 | 3 | VITULLO NICOLE By Domain Partners VI, L.P. | RGDO | Common Stock | I | 35.547 | ||||||||
| 2013-08-21 | 3 | NEFF P SHERRILL | RGDO | Common Stock, par value $0.001 per share | I | 35.928 | ||||||||
| 2013-08-21 | 3 | QUAKER BIOVENTURES CAPITAL LP | RGDO | Common Stock, par value $0.001 per share | D | 35.928 | ||||||||
| 2013-08-21 | 3 | Halak Brian K By Domain Associates, LLC | RGDO | Common Stock | I | 17.171 | ||||||||
| 2013-08-21 | 3 | Clark B. Jefferson See Footnote 1 | RGDO | Common Stock, par value $0.001 per share | I | 19.311 | ||||||||
| 2013-08-21 | 3 | Kamdar Kim P. By Domain Associates, LLC | RGDO | Common Stock | I | 17.171 | ||||||||
| 2013-08-21 | 3 | Rusconi Christopher Paul | RGDO | Common Stock, par value $0.001 per share | D | 22.904 | ||||||||
| 2013-08-21 | 3 | KIERLIN ROBERT A | RGDO | Common Stock, par value $0.001 per share | D | 22.478 |
P
Offener Markt oder privater Kauf von nicht-derivativen oder derivativen Wertpapieren
S
Freiverkauf oder privater Verkauf von nicht-derivativen oder derivativen Wertpapieren
A
Gewährung, Vergabe oder sonstiger Erwerb von Wertpapieren des Unternehmens (z. B. eine Option)
C
Umwandlung von Derivaten
D
Verkauf oder Rückübertragung von Wertpapieren an das Unternehmen
F
Zahlung des Ausübungspreises oder der Steuerschuld mit einem Teil der vom Unternehmen erhaltenen Wertpapiere
G
Schenkung von Wertpapieren durch oder an den Insider
K
Aktien-Swaps und ähnliche Absicherungstransaktionen
M
Ausübung oder Umwandlung eines vom Unternehmen erhaltenen derivativen Wertpapiers (z. B. einer Option)
V
Eine freiwillig auf Formular 4 gemeldete Transaktion
J
Sonstige (mit einer Fußnote zur Beschreibung der Transaktion)
