Bicycle Therapeutics plc - Depositary Receipt (Common Stock)
DE ˙ DB ˙ US0887861088
3,56 € ↓ -0,04 (-1,11%)
2026-06-04
AKTIENPREIS
SecurityDE:50BA / Bicycle Therapeutics plc - Depositary Receipt (Common Stock)
InstitutionMorgan Stanley
Latest Disclosed Ownership618,327 shares
Latest Disclosed Value $ 2,869,038
Morgan Stanley reports 32.91% increase in ownership of 50BA / Bicycle Therapeutics plc - Depositary Receipt (Common Stock)

On May 15, 2026 - Morgan Stanley filed a 13F-HR form disclosing ownership of 618,327 shares of Bicycle Therapeutics plc - Depositary Receipt (Common Stock) (DE:50BA) valued at $2,287,810 USD as of March 31, 2026. The entity filed a previous 13F-HR/A on May 27, 2026 disclosing 465,222 shares of Bicycle Therapeutics plc - Depositary Receipt (Common Stock). This represents a change in shares of 32.91% during the quarter. The current value of the position is $2,201,244 USD.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date
Effective
Date
Form Security Class ID Avg Price
Paid (Est)
Reported
Shares
ΔShares ΔShares
(%)
Reported
Value
(x1000)
ΔValue
(%)
Alloc
(%)
ΔAlloc ΔAlloc (%) Cost Basis
(x1000)
Unrealized
Gain/Loss
(x1000)
2026-05-15 2026-03-31 13F BICYCLE THERAPEUTICS SPONSORED ADS 088786108 618,327 153,105 32.91 2,869 -12.88 0.0002
2026-05-27 2025-12-31 13F/A-1 BICYCLE THERAPEUTICS SPONSORED ADS 088786108 465,222 -357,483 -43.45 3,294 -48.28 0.0002
2026-02-13 2025-12-31 13F BICYCLE THERAPEUTICS SPONSORED ADS 088786108 465,222 -357,483 3,294 0.0002
2026-05-27 2025-09-30 13F/A-1 BICYCLE THERAPEUTICS SPONSORED ADS 088786108 822,705 -214,448 -20.68 6,368 -11.67 0.0004
2025-11-14 2025-09-30 13F BICYCLE THERAPEUTICS SPONSORED ADS 088786108 822,705 -214,448 6,368 0.0004
2025-08-15 2025-06-30 13F BICYCLE THERAPEUTICS SPONSORED ADS 088786108 1,037,153 37,316 3.73 7,208 -15.08 0.0005
2025-05-15 2025-03-31 13F BICYCLE THERAPEUTICS SPONSORED ADS 088786108 999,837 137,700 15.97 8,489 -29.67 0.0006
2025-05-15 2024-12-31 13F/A-1 BICYCLE THERAPEUTICS SPONSORED ADS 088786108 862,137 -487,757 -36.13 12,070 -60.49 0.0008
2025-02-14 2024-12-31 13F BICYCLE THERAPEUTICS SPONSORED ADS 088786108 862,137 -487,757 12,070 0.0008
2025-05-14 2024-09-30 13F/A-2 BICYCLE THERAPEUTICS SPONSORED ADS 088786108 1,349,894 118,321 9.61 30,548 22.55 0.0022
2025-02-14 2024-09-30 13F/A-1 BICYCLE THERAPEUTICS SPONSORED ADS 088786108 1,349,894 118,321 30,548 0.0022
2024-11-14 2024-09-30 13F BICYCLE THERAPEUTICS SPONSORED ADS 088786108 1,349,894 118,321 30,548 0.0003
2025-05-14 2024-06-30 13F/A-2 BICYCLE THERAPEUTICS SPONSORED ADS 088786108 1,231,573 -285,142 -18.80 24,927 -34.00 0.0019
2024-10-17 2024-06-30 13F/A-1 BICYCLE THERAPEUTICS SPONSORED ADS 088786108 1,231,573 -285,142 24,927 0.0019
2024-08-14 2024-06-30 13F BICYCLE THERAPEUTICS SPONSORED ADS 088786108 1,231,573 -285,142 24,927 0.0019
2024-10-17 2024-03-31 13F/A-2 BICYCLE THERAPEUTICS SPONSORED ADS 088786108 1,516,715 487,490 47.36 37,766 102.96 0.0030
2024-08-16 2024-03-31 13F/A-1 BICYCLE THERAPEUTICS SPONSORED ADS 088786108 1,516,715 487,490 37,766 0.0004
2024-05-15 2024-03-31 13F BICYCLE THERAPEUTICS SPONSORED ADS 088786108 1,516,715 487,490 37,766 0.0030
2024-08-16 2023-12-31 13F/A-1 BICYCLE THERAPEUTICS SPONSORED ADS 088786108 1,029,225 -592,524 -36.54 18,608 -42.89 0.0016
2024-02-13 2023-12-31 13F BICYCLE THERAPEUTICS SPONSORED ADS 088786108 1,029,225 -592,524 18,608 0.0016
2023-11-15 2023-09-30 13F BICYCLE THERAPEUTICS SPONSORED ADS 088786108 1,621,749 182,182 12.66 32,581 -11.32 0.0033
2023-08-14 2023-06-30 13F BICYCLE THERAPEUTICS SPONSORED ADS 088786108 1,439,567 -68,182 -4.52 36,738 14.56 0.0036
2023-05-15 2023-03-31 13F BICYCLE THERAPEUTICS SPONSORED ADS 088786108 1,507,749 786,190 108.96 32,070 50.15 0.0034
2023-02-14 2022-12-31 13F BICYCLE THERAPEUTICS SPONSORED ADS 088786108 721,559 -138,292 -16.08 21,358 6.79 0.0024
2022-11-14 2022-09-30 13F BICYCLE THERAPEUTICS SPONSORED ADS 088786108 859,851 38,647 4.71 20,000 45.14 0.0027
2022-10-27 2022-06-30 13F/A-1 BICYCLE THERAPEUTICS SPONSORED ADS 088786108 821,204 733,287 834.07 13,780 257.27 0.0018
2022-08-15 2022-06-30 13F BICYCLE THERAPEUTICS SPONSORED ADS 088786108 821,204 733,287 13,780 0.0018
2022-10-27 2022-03-31 13F/A-1 BICYCLE THERAPEUTICS SPONSORED ADS 088786108 87,917 -62,095 -41.39 3,857 -57.76 0.0005
2022-05-13 2022-03-31 13F BICYCLE THERAPEUTICS SPONSORED ADS 088786108 87,917 -62,095 3,857 0.0005
2022-02-14 2021-12-31 13F BICYCLE THERAPEUTICS SPONSORED ADS 088786108 150,012 5,399 3.73 9,131 51.80 0.0011
2021-11-15 2021-09-30 13F BICYCLE THERAPEUTICS SPONSORED ADS 088786108 144,613 78,407 118.43 6,015 199.25 0.0008
2021-08-23 2021-06-30 13F/A-1 BICYCLE THERAPEUTICS SPONSORED ADS 088786108 66,206 63,966 2,855.62 2,010 2,900.00 0.0003
2021-08-16 2021-06-30 13F BICYCLE THERAPEUTICS SPONSORED ADS 088786108 66,206 63,966 2,010 0.0001
2021-05-17 2021-03-31 13F BICYCLE THERAPEUTICS SPONSORED ADS 088786108 2,240 -1,232 -35.48 67 8.06 0.0000
2021-02-16 2020-12-31 13F BICYCLE THERAPEUTICS SPONSORED ADS 088786108 3,472 -517 -12.96 62 -18.42 0.0000
2020-11-13 2020-09-30 13F BICYCLE THERAPEUTICS SPONSORED ADS 088786108 3,989 515 14.82 76 38.18 0.0000
2020-08-14 2020-06-30 13F BICYCLE THERAPEUTICS SPONSORED ADS 088786108 3,474 219 6.73 55 25.00 0.0000
2020-05-26 2020-03-31 13F/A-1 BICYCLE THERAPEUTICS SPONSORED ADS 088786108 3,255 3,245 32,450.00 44 -20.00 0.0000
2020-05-15 2020-03-31 13F BICYCLE THERAPEUTICS SPONSORED ADS 088786108 3,255 3,245 44 3.3801
2020-02-14 2019-12-31 13F BICYCLE THERAPEUTICS SPONSORED ADS 088786108 10 10 0 0.0000
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.