Ionis Pharmaceuticals, Inc.
GB ˙ LSE ˙ US4622221004
75,40 $ ↑1,57 (2,13%)
2026-06-04
AKTIENPREIS
SecurityGB:0JDI / Ionis Pharmaceuticals, Inc.
InstitutionXponance, Inc.
Latest Disclosed Ownership26,384 shares
Latest Disclosed Value $ 1,981,175
Xponance, Inc. reports 15.01% increase in ownership of 0JDI / Ionis Pharmaceuticals, Inc.

On May 13, 2026 - Xponance, Inc. filed a 13F-HR form disclosing ownership of 26,384 shares of Ionis Pharmaceuticals, Inc. (GB:0JDI) valued at $1,984,024 USD as of March 31, 2026. The entity filed a previous 13F-HR on February 12, 2026 disclosing 22,941 shares of Ionis Pharmaceuticals, Inc.. This represents a change in shares of 15.01% during the quarter. The current value of the position is $1,989,354 USD.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date		 Effective
Date		Form Security Class ID Avg Price
Paid (Est)		 Reported
Shares		 ΔShares ΔShares
(%)		 Reported
Value
(x1000)		 ΔValue
(%)		 Alloc
(%)		 ΔAlloc ΔAlloc (%) Cost Basis
(x1000)		 Unrealized
Gain/Loss
(x1000)
2026-05-13 2026-03-31 13F IONIS PHARMACEUTICALS COM 462222100 26,384 3,443 15.01 1,981 9.21 0.0141
2026-02-12 2025-12-31 13F IONIS PHARMACEUTICALS COM 462222100 22,941 1,491 6.95 1,815 29.29 0.0136
2025-11-12 2025-09-30 13F IONIS PHARMACEUTICALS COM 462222100 21,450 -1,304 -5.73 1,403 56.06 0.0111
2025-08-14 2025-06-30 13F IONIS PHARMACEUTICALS COM 462222100 22,754 2,435 11.98 899 46.66 0.0075
2025-05-01 2025-03-31 13F IONIS PHARMACEUTICALS COM 462222100 20,319 980 5.07 613 -9.32 0.0059
2025-02-11 2024-12-31 13F IONIS PHARMACEUTICALS COM 462222100 19,339 318 1.67 676 -11.17 0.0062
2024-11-12 2024-09-30 13F IONIS PHARMACEUTICALS COM 462222100 19,021 906 5.00 762 -11.82 0.0074
2024-08-14 2024-06-30 13F IONIS PHARMACEUTICALS COM 462222100 18,115 1,906 11.76 863 22.93 0.0088
2024-05-13 2024-03-31 13F IONIS PHARMACEUTICALS COM 462222100 16,209 -484 -2.90 703 -16.82 0.0074
2024-01-31 2023-12-31 13F IONIS PHARMACEUTICALS COM 462222100 16,693 -1,143 -6.41 844 4.33 0.0101
2023-10-24 2023-09-30 13F IONIS PHARMACEUTICALS COM 462222100 17,836 -430 -2.35 809 8.01 0.0110
2023-07-14 2023-06-30 13F IONIS PHARMACEUTICALS COM 462222100 18,266 339 1.89 749 17.03 0.0100
2023-04-18 2023-03-31 13F IONIS PHARMACEUTICALS COM 462222100 17,927 217 1.23 641 -4.19 0.0094
2023-01-24 2022-12-31 13F IONIS PHARMACEUTICALS COM 462222100 17,710 2,170 13.96 669 -2.77 0.0108
2022-10-24 2022-09-30 13F IONIS PHARMACEUTICALS COM 462222100 15,540 122 0.79 687 20.32 0.0132
2022-08-02 2022-06-30 13F IONIS PHARMACEUTICALS COM 462222100 15,418 520 3.49 571 3.44 0.0115
2022-04-20 2022-03-31 13F IONIS PHARMACEUTICALS COM 462222100 14,898 8 0.05 552 21.85 0.0092
2022-01-31 2021-12-31 13F IONIS PHARMACEUTICALS COM 462222100 14,890 318 2.18 453 -7.36 0.0071
2021-11-05 2021-09-30 13F IONIS PHARMACEUTICALS COM 462222100 14,572 -654 -4.30 489 -19.44 0.0093
2021-08-12 2021-06-30 13F IONIS PHARMACEUTICALS COM 462222100 15,226 8,423 123.81 607 98.37 0.0112
2021-05-10 2021-03-31 13F IONIS PHARMACEUTICALS COM 462222100 6,803 23 0.34 306 -20.10 0.0065
2021-02-11 2020-12-31 13F IONIS PHARMACEUTICALS COM 462222100 6,780 209 3.18 383 22.76 0.0083
2020-10-26 2020-09-30 13F IONIS PHARMACEUTICALS COM 462222100 6,571 -215 -3.17 312 -22.00 0.0077
2020-08-14 2020-06-30 13F IONIS PHARMACEUTICALS COM 462222100 6,786 6,786 400 0.0103
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.