Arrowhead Pharmaceuticals, Inc.
MX ˙ BMV ˙ US04280A1007
SecurityMX:ARWR / Arrowhead Pharmaceuticals, Inc.
InstitutionProfund Advisors Llc
Latest Disclosed Ownership39,758 shares
Latest Disclosed Value $ 2,492,827
Profund Advisors Llc reports 8.80% increase in ownership of ARWR / Arrowhead Pharmaceuticals, Inc.

On April 24, 2026 - Profund Advisors Llc filed a 13F-HR form disclosing ownership of 39,758 shares of Arrowhead Pharmaceuticals, Inc. (MX:ARWR) valued at $2,492,827 USD as of March 31, 2026. The entity filed a previous 13F-HR on February 6, 2026 disclosing 36,542 shares of Arrowhead Pharmaceuticals, Inc.. This represents a change in shares of 8.80% during the quarter.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date		 Effective
Date		Form Security Class ID Avg Price
Paid (Est)		 Reported
Shares		 ΔShares ΔShares
(%)		 Reported
Value
(x1000)		 ΔValue
(%)		 Alloc
(%)		 ΔAlloc ΔAlloc (%) Cost Basis
(x1000)		 Unrealized
Gain/Loss
(x1000)
2026-04-24 2026-03-31 13F ARROWHEAD PHARMACEUTICALS IN COM 04280A100 39,758 3,216 8.80 2,493 2.72 0.0915
2026-02-06 2025-12-31 13F ARROWHEAD PHARMACEUTICALS IN COM 04280A100 36,542 7,108 24.15 2,426 139.01 0.0737
2025-11-06 2025-09-30 13F ARROWHEAD PHARMACEUTICALS IN COM 04280A100 29,434 -4,454 -13.14 1,015 89.72 0.0330
2025-08-07 2025-06-30 13F ARROWHEAD PHARMACEUTICALS IN COM 04280A100 33,888 -9,857 -22.53 535 -3.95 0.0193
2025-05-08 2025-03-31 13F ARROWHEAD PHARMACEUTICALS IN COM 04280A100 43,745 13,250 43.45 557 -2.79 0.0242
2025-02-14 2024-12-31 13F ARROWHEAD PHARMACEUTICALS IN COM 04280A100 30,495 -9,259 -23.29 573 -25.58 0.0209
2024-11-14 2024-09-30 13F ARROWHEAD PHARMACEUTICALS IN COM 04280A100 39,754 7,751 24.22 770 -7.34 0.0291
2024-08-13 2024-06-30 13F ARROWHEAD PHARMACEUTICALS IN COM 04280A100 32,003 -16,957 -34.63 832 -40.64 0.0308
2024-05-08 2024-03-31 13F ARROWHEAD PHARMACEUTICALS IN COM 04280A100 48,960 -14,593 -22.96 1,400 -27.98 0.0545
2024-02-14 2023-12-31 13F ARROWHEAD PHARMACEUTICALS IN COM 04280A100 63,553 9,636 17.87 1,945 34.25 0.0835
2023-11-13 2023-09-30 13F ARROWHEAD PHARMACEUTICALS IN COM 04280A100 53,917 6,830 14.51 1,449 -13.76 0.0801
2023-08-10 2023-06-30 13F ARROWHEAD PHARMACEUTICALS IN COM 04280A100 47,087 -5,715 -10.82 1,679 25.21 0.0901
2023-05-12 2023-03-31 13F ARROWHEAD PHARMACEUTICALS IN COM 04280A100 52,802 34,803 193.36 1,341 83.70 0.0829
2023-02-02 2022-12-31 13F ARROWHEAD PHARMACEUTICALS IN COM 04280A100 17,999 523 2.99 730 26.30 0.0474
2022-11-07 2022-09-30 13F ARROWHEAD PHARMACEUTICALS IN COM 04280A100 17,476 -316 -1.78 578 -7.67 0.0416
2022-08-01 2022-06-30 13F ARROWHEAD PHARMACEUTICALS IN COM 04280A100 17,792 -2,567 -12.61 626 -33.12 0.0398
2022-05-10 2022-03-31 13F ARROWHEAD PHARMACEUTICALS IN COM 04280A100 20,359 -2,053 -9.16 936 -37.01 0.0393
2022-02-08 2021-12-31 13F ARROWHEAD PHARMACEUTICALS IN COM 04280A100 22,412 -2,487 -9.99 1,486 -4.38 0.0486
2021-11-12 2021-09-30 13F ARROWHEAD PHARMACEUTICALS IN COM 04280A100 24,899 16,420 193.65 1,554 121.37 0.0524
2021-08-12 2021-06-30 13F ARROWHEAD PHARMACEUTICALS IN COM 04280A100 8,479 -241 -2.76 702 21.45 0.0236
2021-05-14 2021-03-31 13F ARROWHEAD PHARMACEUTICALS IN COM 04280A100 8,720 -1,173 -11.86 578 -23.85 0.0222
2021-02-09 2020-12-31 13F ARROWHEAD PHARMACEUTICALS IN COM 04280A100 9,893 627 6.77 759 90.23 0.0332
2020-11-13 2020-09-30 13F ARROWHEAD PHARMACEUTICALS IN COM 04280A100 9,266 3,357 56.81 399 56.47 0.0205
2020-08-03 2020-06-30 13F ARROWHEAD PHARMACEUTICALS IN COM 04280A100 5,909 5,909 255 0.0142
2020-05-15 2020-03-31 13F ARROWHEAD PHARMACEUTICALS IN COM 04280A100 0 -9,514 -100.00 0 -100.00
2020-02-18 2019-12-31 13F ARROWHEAD PHARMACEUTICALS IN COM 04280A100 9,514 -54 -0.56 603 123.33 0.0263
2019-11-12 2019-09-30 13F ARROWHEAD PHARMACEUTICALS IN COM 04280A100 9,568 278 2.99 270 9.76 0.0137
2019-08-13 2019-06-30 13F ARROWHEAD PHARMACEUTICALS IN COM 04280A100 9,290 9,290 246 0.0117
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.