BioCryst Pharmaceuticals, Inc.
MX ˙ BMV ˙ US09058V1035
SecurityMX:BCRX / BioCryst Pharmaceuticals, Inc.
InstitutionMorgan Stanley
Latest Disclosed Ownership2,022,988 shares
Latest Disclosed Value $ 19,258,852
Morgan Stanley reports 15.89% increase in ownership of BCRX / BioCryst Pharmaceuticals, Inc.

On May 15, 2026 - Morgan Stanley filed a 13F-HR form disclosing ownership of 2,022,988 shares of BioCryst Pharmaceuticals, Inc. (MX:BCRX) valued at $19,258,852 USD as of March 31, 2026. The entity filed a previous 13F-HR/A on May 27, 2026 disclosing 1,745,563 shares of BioCryst Pharmaceuticals, Inc.. This represents a change in shares of 15.89% during the quarter.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date		 Effective
Date		Form Security Class ID Avg Price
Paid (Est)		 Reported
Shares		 ΔShares ΔShares
(%)		 Reported
Value
(x1000)		 ΔValue
(%)		 Alloc
(%)		 ΔAlloc ΔAlloc (%) Cost Basis
(x1000)		 Unrealized
Gain/Loss
(x1000)
2026-05-15 2026-03-31 13F BIOCRYST PHARMACEUTICALS COM 09058V103 2,022,988 277,425 15.89 19,259 41.45 0.0012
2026-05-27 2025-12-31 13F/A-1 BIOCRYST PHARMACEUTICALS COM 09058V103 1,745,563 -3,457,396 -66.45 13,615 -65.52 0.0008
2026-02-13 2025-12-31 13F BIOCRYST PHARMACEUTICALS COM 09058V103 1,745,563 -3,457,396 13,615 0.0008
2026-05-27 2025-09-30 13F/A-1 BIOCRYST PHARMACEUTICALS COM 09058V103 5,202,959 -126,720 -2.38 39,490 -17.30 0.0024
2025-11-14 2025-09-30 13F BIOCRYST PHARMACEUTICALS COM 09058V103 5,202,959 -126,720 39,490 0.0024
2025-08-15 2025-06-30 13F BIOCRYST PHARMACEUTICALS COM 09058V103 5,329,679 3,032,005 131.96 47,754 177.12 0.0031
2025-05-15 2025-03-31 13F BIOCRYST PHARMACEUTICALS COM 09058V103 2,297,674 631,942 37.94 17,233 37.57 0.0012
2025-05-15 2024-12-31 13F/A-1 BIOCRYST PHARMACEUTICALS COM 09058V103 1,665,732 -73,348 -4.22 12,526 -5.23 0.0009
2025-02-14 2024-12-31 13F BIOCRYST PHARMACEUTICALS COM 09058V103 1,665,732 -73,348 12,526 0.0009
2025-05-14 2024-09-30 13F/A-2 BIOCRYST PHARMACEUTICALS COM 09058V103 1,739,080 161,131 10.21 13,217 35.55 0.0010
2025-02-14 2024-09-30 13F/A-1 BIOCRYST PHARMACEUTICALS COM 09058V103 1,739,080 161,131 13,217 0.0010
2024-11-14 2024-09-30 13F BIOCRYST PHARMACEUTICALS COM 09058V103 1,739,080 161,131 13,217 0.0001
2025-05-14 2024-06-30 13F/A-2 BIOCRYST PHARMACEUTICALS COM 09058V103 1,577,949 -430,096 -21.42 9,752 -4.40 0.0008
2024-10-17 2024-06-30 13F/A-1 BIOCRYST PHARMACEUTICALS COM 09058V103 1,577,949 -430,096 9,752 0.0008
2024-08-14 2024-06-30 13F BIOCRYST PHARMACEUTICALS COM 09058V103 1,577,949 -430,096 9,752 0.0008
2024-10-17 2024-03-31 13F/A-2 BIOCRYST PHARMACEUTICALS COM 09058V103 2,008,045 -1,128,643 -35.98 10,201 -45.71 0.0008
2024-08-16 2024-03-31 13F/A-1 BIOCRYST PHARMACEUTICALS COM 09058V103 2,008,045 -1,128,643 10,201 0.0001
2024-05-15 2024-03-31 13F BIOCRYST PHARMACEUTICALS COM 09058V103 2,008,045 -1,128,643 10,201 0.0008
2024-08-16 2023-12-31 13F/A-1 BIOCRYST PHARMACEUTICALS COM 09058V103 3,136,688 1,310,864 71.80 18,789 45.35 0.0017
2024-02-13 2023-12-31 13F BIOCRYST PHARMACEUTICALS COM 09058V103 3,136,688 1,310,864 18,789 0.0017
2023-11-15 2023-09-30 13F BIOCRYST PHARMACEUTICALS COM 09058V103 1,825,824 956,027 109.91 12,927 111.11 0.0013
2023-08-14 2023-06-30 13F BIOCRYST PHARMACEUTICALS COM 09058V103 869,797 -740,873 -46.00 6,123 -54.41 0.0006
2023-05-15 2023-03-31 13F BIOCRYST PHARMACEUTICALS COM 09058V103 1,610,670 454,939 39.36 13,433 1.24 0.0014
2023-02-14 2022-12-31 13F BIOCRYST PHARMACEUTICALS COM 09058V103 1,155,731 246,462 27.11 13,268 15.80 0.0015
2022-11-14 2022-09-30 13F BIOCRYST PHARMACEUTICALS COM 09058V103 909,269 -3,466,300 -79.22 11,457 -75.25 0.0016
2022-10-27 2022-06-30 13F/A-1 BIOCRYST PHARMACEUTICALS COM 09058V103 4,375,569 3,665,522 516.24 46,294 300.99 0.0060
2022-08-15 2022-06-30 13F BIOCRYST PHARMACEUTICALS COM 09058V103 4,375,569 3,665,522 46,294 0.0012
2022-10-27 2022-03-31 13F/A-1 BIOCRYST PHARMACEUTICALS COM 09058V103 710,047 333,678 88.66 11,545 121.47 0.0016
2022-05-13 2022-03-31 13F BIOCRYST PHARMACEUTICALS COM 09058V103 710,047 333,678 11,545 0.0016
2022-02-14 2021-12-31 13F BIOCRYST PHARMACEUTICALS COM 09058V103 376,369 -49,008 -11.52 5,213 -14.74 0.0006
2021-11-15 2021-09-30 13F BIOCRYST PHARMACEUTICALS COM 09058V103 425,377 -486,828 -53.37 6,114 -57.61 0.0008
2021-08-23 2021-06-30 13F/A-1 BIOCRYST PHARMACEUTICALS COM 09058V103 912,205 654,998 254.66 14,423 451.34 0.0019
2021-08-16 2021-06-30 13F BIOCRYST PHARMACEUTICALS COM 09058V103 912,205 654,998 14,423 0.0004
2021-05-17 2021-03-31 13F BIOCRYST PHARMACEUTICALS COM 09058V103 257,207 -17,940 -6.52 2,616 27.55 0.0004
2021-02-16 2020-12-31 13F BIOCRYST PHARMACEUTICALS COM 09058V103 275,147 81,750 42.27 2,051 208.89 0.0003
2020-11-13 2020-09-30 13F BIOCRYST PHARMACEUTICALS COM 09058V103 193,397 -18,996 -8.94 664 -34.39 0.0001
2020-08-14 2020-06-30 13F BIOCRYST PHARMACEUTICALS COM 09058V103 212,393 -479,755 -69.31 1,012 -26.83 0.0002
2020-05-26 2020-03-31 13F/A-1 BIOCRYST PHARMACEUTICALS COM 09058V103 692,148 183,081 35.96 1,383 -21.24 0.0004
2020-05-15 2020-03-31 13F BIOCRYST PHARMACEUTICALS COM 09058V103 692,148 183,081 1,383 106.2432
2020-02-14 2019-12-31 13F BIOCRYST PHARMACEUTICALS COM 09058V103 509,067 -739,249 -59.22 1,756 -50.89 0.0004
2019-11-14 2019-09-30 13F BIOCRYST PHARMACEUTICALS COM 09058V103 1,248,316 -164,337 -11.63 3,576 -33.21 0.0009
2019-08-14 2019-06-30 13F BIOCRYST PHARMACEUTICALS COM 09058V103 1,412,653 1,045,869 285.15 5,354 79.30 0.0014
2019-05-15 2019-03-31 13F BIOCRYST PHARMACEUTICALS COM 09058V103 366,784 183,081 99.66 2,986 101.35 0.0008
2019-02-14 2018-12-31 13F BIOCRYST PHARMACEUTICALS COM 09058V103 183,703 -9,016 -4.68 1,483 0.88 0.0004
2019-04-23 2018-09-30 13F/A-2 BIOCRYST PHARMACEUTICALS COM 09058V103 192,719 -48,610 -20.14 1,470 6.29 0.0004
2018-11-20 2018-09-30 13F/A-1 BIOCRYST PHARMACEUTICALS COM 09058V103 192,719 0 1,470 0.0004
2018-11-14 2018-09-30 13F BIOCRYST PHARMACEUTICALS COM 09058V103 192,719 -48,610 1,470
2019-04-23 2018-06-30 13F/A-1 BIOCRYST PHARMACEUTICALS COM 09058V103 241,329 -200,102 -45.33 1,383 -34.33 0.0004
2018-08-14 2018-06-30 13F BIOCRYST PHARMACEUTICALS COM 09058V103 241,329 -200,102 1,383
2019-04-23 2018-03-31 13F/A-1 BIOCRYST PHARMACEUTICALS COM 09058V103 441,431 52,726 13.56 2,106 10.38 0.0006
2018-05-14 2018-03-31 13F BIOCRYST PHARMACEUTICALS COM 09058V103 441,431 52,726 2,106
2019-04-23 2017-12-31 13F/A-1 BIOCRYST PHARMACEUTICALS COM 09058V103 388,705 26,565 7.34 1,908 0.53 0.0005
2018-02-14 2017-12-31 13F BIOCRYST PHARMACEUTICALS COM 09058V103 388,705 26,565 1,908
2017-11-14 2017-09-30 13F BIOCRYST PHARMACEUTICALS COM 09058V103 362,140 44,241 13.92 1,898 7.35 0.0006
2017-08-11 2017-06-30 13F BIOCRYST PHARMACEUTICALS COM 09058V103 317,899 -156,286 -32.96 1,768 -55.61 0.0005
2017-05-22 2017-03-31 13F/A-1 BIOCRYST PHARMACEUTICALS COM 09058V103 474,185 146,220 44.58 3,983 91.86 0.0012
2017-05-12 2017-03-31 13F BIOCRYST PHARMACEUTICALS COM 09058V103 474,185 3,983
2017-02-22 2016-12-31 13F/A-1 BIOCRYST PHARMACEUTICALS COM 09058V103 327,965 302,642 1,195.13 2,076 1,753.57 0.0007
2017-02-13 2016-12-31 13F BIOCRYST PHARMACEUTICALS COM 09058V103 327,965 2,076
2016-11-10 2016-09-30 13F BIOCRYST PHARMACEUTICALS COM 09058V103 25,323 8,529 50.79 112 133.33 0.0000
2016-08-12 2016-06-30 13F BIOCRYST PHARMACEUTICALS COM 09058V103 16,794 -163,431 -90.68 48 -90.59 0.0000
2016-05-12 2016-03-31 13F BIOCRYST PHARMACEUTICALS COM 09058V103 180,225 76,421 73.62 510 -52.38 0.0002
2016-02-09 2015-12-31 13F BIOCRYST PHARMACEUTICALS COM 09058V103 103,804 12,646 13.87 1,071 3.08 0.0004
2016-02-08 2015-09-30 13F/A-1 BIOCRYST PHARMACEUTICALS COM 09058V103 91,158 -7,934 -8.01 1,039 -29.75 0.0004
2015-11-09 2015-09-30 13F BIOCRYST PHARMACEUTICALS COM 09058V103 91,158 1,039
2015-08-12 2015-06-30 13F BIOCRYST PHARMACEUTICALS COM 09058V103 99,092 327 0.33 1,479 65.81 0.0005
2015-05-14 2015-03-31 13F BIOCRYST PHARMACEUTICALS COM 09058V103 98,765 37,571 61.40 892 19.73 0.0003
2015-02-13 2014-12-31 13F BIOCRYST PHARMACEUTICALS COM 09058V103 61,194 -227,022 -78.77 745 -73.57 0.0003
2014-12-16 2014-09-30 13F/A-1 BIOCRYST PHARMACEUTICALS COM 09058V103 288,216 -202,818 -41.30 2,819 -54.98 0.0011
2014-11-14 2014-09-30 13F BIOCRYST PHARMACEUTICALS COM 09058V103 288,216 2,819
2014-08-12 2014-06-30 13F BIOCRYST PHARMACEUTICALS COM 09058V103 491,034 -34,272 -6.52 6,261 12.63 0.0107
2014-05-13 2014-03-31 13F BIOCRYST PHARMACEUTICALS COM 09058V103 525,306 -7,706 -1.45 5,559 37.23 0.0023
2014-02-13 2013-12-31 13F BIOCRYST PHARMACEUTICALS COM 09058V103 533,012 458,179 612.27 4,051 644.67 0.0017
2013-11-13 2013-09-30 13F BIOCRYST PHARMACEUTICALS IN COM 09058V103 74,833 -104,494 -58.27 544 95.68 0.0003
2013-08-08 2013-06-30 13F BIOCRYST PHARMACEUTICALS IN COM 09058V103 179,327 179,327 278 0.0001
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.