BioCryst Pharmaceuticals, Inc.
MX ˙ BMV ˙ US09058V1035
SecurityMX:BCRX / BioCryst Pharmaceuticals, Inc.
InstitutionProShare Advisors LLC
Latest Disclosed Ownership44,029 shares
Latest Disclosed Value $ 419,156
ProShare Advisors LLC reports 7.51% decrease in ownership of BCRX / BioCryst Pharmaceuticals, Inc.

On April 24, 2026 - ProShare Advisors LLC filed a 13F-HR form disclosing ownership of 44,029 shares of BioCryst Pharmaceuticals, Inc. (MX:BCRX) valued at $419,156 USD as of March 31, 2026. The entity filed a previous 13F-HR on February 6, 2026 disclosing 47,604 shares of BioCryst Pharmaceuticals, Inc.. This represents a change in shares of -7.51% during the quarter.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date		 Effective
Date		Form Security Class ID Avg Price
Paid (Est)		 Reported
Shares		 ΔShares ΔShares
(%)		 Reported
Value
(x1000)		 ΔValue
(%)		 Alloc
(%)		 ΔAlloc ΔAlloc (%) Cost Basis
(x1000)		 Unrealized
Gain/Loss
(x1000)
2026-04-24 2026-03-31 13F BIOCRYST PHARMACEUTICALS COM 09058V103 44,029 -3,575 -7.51 419 12.94 0.0006
2026-02-06 2025-12-31 13F BIOCRYST PHARMACEUTICALS COM 09058V103 47,604 4,307 9.95 371 13.11 0.0007
2025-11-06 2025-09-30 13F BIOCRYST PHARMACEUTICALS COM 09058V103 43,297 -7,448 -14.68 329 -27.75 0.0007
2025-08-07 2025-06-30 13F BIOCRYST PHARMACEUTICALS COM 09058V103 50,745 -3,413 -6.30 455 11.82 0.0009
2025-05-08 2025-03-31 13F BIOCRYST PHARMACEUTICALS COM 09058V103 54,158 -13,846 -20.36 406 -20.55 0.0009
2025-02-14 2024-12-31 13F BIOCRYST PHARMACEUTICALS COM 09058V103 68,004 16,732 32.63 511 31.36 0.0012
2024-11-14 2024-09-30 13F BIOCRYST PHARMACEUTICALS COM 09058V103 51,272 13,144 34.47 390 65.53 0.0010
2024-08-13 2024-06-30 13F BIOCRYST PHARMACEUTICALS COM 09058V103 38,128 -10,375 -21.39 236 -4.47 0.0006
2024-05-08 2024-03-31 13F BIOCRYST PHARMACEUTICALS COM 09058V103 48,503 4,041 9.09 246 -7.52 0.0007
2024-02-14 2023-12-31 13F BIOCRYST PHARMACEUTICALS COM 09058V103 44,462 7,450 20.13 266 1.53 0.0008
2023-11-13 2023-09-30 13F BIOCRYST PHARMACEUTICALS COM 09058V103 37,012 134 0.36 262 1.16 0.0008
2023-08-10 2023-06-30 13F BIOCRYST PHARMACEUTICALS COM 09058V103 36,878 1,981 5.68 260 -11.00 0.0008
2023-05-26 2023-03-31 13F/A-1 BIOCRYST PHARMACEUTICALS COM 09058V103 34,897 -4,388 -11.17 291 -35.33 0.0009
2023-05-12 2023-03-31 13F BIOCRYST PHARMACEUTICALS COM 09058V103 34,897 -4,388 291 0.0009
2023-02-02 2022-12-31 13F BIOCRYST PHARMACEUTICALS COM 09058V103 39,285 3,202 8.87 451 -1.10 0.0016
2022-11-07 2022-09-30 13F BIOCRYST PHARMACEUTICALS COM 09058V103 36,083 790 2.24 455 21.66 0.0017
2022-08-01 2022-06-30 13F BIOCRYST PHARMACEUTICALS COM 09058V103 35,293 -17,576 -33.24 374 -56.51 0.0012
2022-05-10 2022-03-31 13F BIOCRYST PHARMACEUTICALS COM 09058V103 52,869 -11,704 -18.13 860 -3.80 0.0018
2022-02-08 2021-12-31 13F BIOCRYST PHARMACEUTICALS COM 09058V103 64,573 3,575 5.86 894 1.94 0.0018
2021-11-12 2021-09-30 13F BIOCRYST PHARMACEUTICALS COM 09058V103 60,998 -17,056 -21.85 877 -28.93 0.0025
2021-08-13 2021-06-30 13F BIOCRYST PHARMACEUTICALS COM 09058V103 78,054 6,380 8.90 1,234 69.27 0.0036
2021-05-14 2021-03-31 13F BIOCRYST PHARMACEUTICALS COM 09058V103 71,674 5,294 7.98 729 47.27 0.0023
2021-02-09 2020-12-31 13F BIOCRYST PHARMACEUTICALS COM 09058V103 66,380 16,273 32.48 495 187.79 0.0018
2020-11-13 2020-09-30 13F BIOCRYST PHARMACEUTICALS COM 09058V103 50,107 1,488 3.06 172 -25.86 0.0008
2020-08-03 2020-06-30 13F BIOCRYST PHARMACEUTICALS COM 09058V103 48,619 18,414 60.96 232 286.67 0.0012
2020-05-15 2020-03-31 13F BIOCRYST PHARMACEUTICALS COM 09058V103 30,205 -23,188 -43.43 60 -67.39 0.0004
2020-02-12 2019-12-31 13F BIOCRYST PHARMACEUTICALS COM 09058V103 53,393 10,952 25.81 184 50.82 0.0009
2019-11-12 2019-09-30 13F BIOCRYST PHARMACEUTICALS COM 09058V103 42,441 -1,314 -3.00 122 -26.51 0.0007
2019-08-13 2019-06-30 13F BIOCRYST PHARMACEUTICALS COM 09058V103 43,755 -5,356 -10.91 166 -58.50 0.0010
2019-05-15 2019-03-31 13F BIOCRYST PHARMACEUTICALS COM 09058V103 49,111 451 0.93 400 1.78 0.0024
2019-02-14 2018-12-31 13F BIOCRYST PHARMACEUTICALS COM 09058V103 48,660 -9,293 -16.04 393 -11.09 0.0028
2018-11-14 2018-09-30 13F BIOCRYST PHARMACEUTICALS COM 09058V103 57,953 3,451 6.33 442 41.67 0.0030
2018-08-13 2018-06-30 13F BIOCRYST PHARMACEUTICALS COM 09058V103 54,502 -3,533 -6.09 312 12.64 0.0021
2018-05-14 2018-03-31 13F BIOCRYST PHARMACEUTICALS COM 09058V103 58,035 -9,526 -14.10 277 -16.57 0.0018
2018-02-14 2017-12-31 13F BIOCRYST PHARMACEUTICALS COM 09058V103 67,561 16,754 32.98 332 24.81 0.0023
2017-11-13 2017-09-30 13F BIOCRYST PHARMACEUTICALS COM 09058V103 50,807 2,453 5.07 266 -1.12 0.0024
2017-08-11 2017-06-30 13F BIOCRYST PHARMACEUTICALS COM 09058V103 48,354 427 0.89 269 -33.25 0.0027
2017-05-12 2017-03-31 13F/A-2 BIOCRYST PHARMACEUTICALS COM 09058V103 47,927 -12,600 -20.82 403 5.22 0.0042
2017-05-08 2017-03-31 13F/A-1 BIOCRYST PHARMACEUTICALS COM 09058V103 47,927 0 403 0.0042
2017-04-25 2017-03-31 13F BIOCRYST PHARMACEUTICALS COM 09058V103 47,927 403
2017-02-13 2016-12-31 13F BIOCRYST PHARMACEUTICALS COM 09058V103 60,527 6,790 12.64 383 61.60 0.0042
2016-11-10 2016-09-30 13F BIOCRYST PHARMACEUTICALS COM 09058V103 53,737 -10,106 -15.83 237 30.94 0.0033
2016-08-12 2016-06-30 13F BIOCRYST PHARMACEUTICALS COM 09058V103 63,843 876 1.39 181 1.69 0.0023
2016-05-06 2016-03-31 13F BIOCRYST PHARMACEUTICALS COM 09058V103 62,967 -6,565 -9.44 178 -75.21 0.0025
2016-02-05 2015-12-31 13F BIOCRYST PHARMACEUTICALS COM 09058V103 69,532 6,755 10.76 718 0.28 0.0087
2015-11-06 2015-09-30 13F BIOCRYST PHARMACEUTICALS COM 09058V103 62,777 -4,319 -6.44 716 -28.54 0.0101
2015-08-11 2015-06-30 13F BIOCRYST PHARMACEUTICALS COM 09058V103 67,096 -4,345 -6.08 1,002 55.35 0.0139
2015-05-08 2015-03-31 13F BIOCRYST PHARMACEUTICALS COM 09058V103 71,441 71,441 0.00 645 0.0076
2015-01-30 2014-12-31 13F BIOCRYST PHARMACEUTICALS COM 09058V103 0 -64,742 -100.00 0 -100.00
2014-11-06 2014-09-30 13F BIOCRYST PHARMACEUTICALS COM 09058V103 64,742 -11,866 -15.49 633 -35.21 0.0084
2014-08-08 2014-06-30 13F BIOCRYST PHARMACEUTICALS COM 09058V103 76,608 31,373 69.36 977 103.97 0.0127
2014-05-07 2014-03-31 13F BIOCRYST PHARMACEUTICALS COM 09058V103 45,235 19,349 74.75 479 143.15 0.0060
2014-02-04 2013-12-31 13F BIOCRYST PHARMACEUTICALS COM 09058V103 25,886 25,886 -25.18 197 264.81 0.0029
2013-11-07 2013-09-30 13F BIOCRYST PHARMACEUTICALS COM 09058V103 0 -34,599 -100.00 0 -100.00
2013-07-25 2013-06-30 13F BIOCRYST PHARMACEUTICALS COM 09058V103 34,599 34,599 54 0.0011
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.