Guardant Health, Inc.
MX ˙ BMV ˙ US40131M1099
SecurityMX:GH / Guardant Health, Inc.
InstitutionPrincipal Financial Group Inc
Latest Disclosed Ownership184,846 shares
Latest Disclosed Value $ 17,074,225
Principal Financial Group Inc reports 20.20% increase in ownership of GH / Guardant Health, Inc.

On May 4, 2026 - Principal Financial Group Inc filed a 13F-HR form disclosing ownership of 184,846 shares of Guardant Health, Inc. (MX:GH) valued at $17,074,225 USD as of March 31, 2026. The entity filed a previous 13F-HR on February 2, 2026 disclosing 153,782 shares of Guardant Health, Inc.. This represents a change in shares of 20.20% during the quarter.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date		 Effective
Date		Form Security Class ID Avg Price
Paid (Est)		 Reported
Shares		 ΔShares ΔShares
(%)		 Reported
Value
(x1000)		 ΔValue
(%)		 Alloc
(%)		 ΔAlloc ΔAlloc (%) Cost Basis
(x1000)		 Unrealized
Gain/Loss
(x1000)
2026-05-04 2026-03-31 13F GUARDANT HEALTH COM 40131M109 184,846 31,064 20.20 17,074 8.70 0.0047
2026-02-02 2025-12-31 13F GUARDANT HEALTH COM 40131M109 153,782 -22,734 -12.88 15,707 42.43 0.0080
2025-11-04 2025-09-30 13F GUARDANT HEALTH COM 40131M109 176,516 -86,006 -32.76 11,029 -19.27 0.0056
2025-08-08 2025-06-30 13F GUARDANT HEALTH COM 40131M109 262,522 -235,607 -47.30 13,662 -35.62 0.0072
2025-04-28 2025-03-31 13F GUARDANT HEALTH COM 40131M109 498,129 488,043 4,838.82 21,220 6,789.61 0.0119
2025-01-31 2024-12-31 13F GUARDANT HEALTH COM 40131M109 10,086 -880 -8.02 308 22.71 0.0002
2024-10-31 2024-09-30 13F GUARDANT HEALTH COM 40131M109 10,966 -4,976 -31.21 252 -45.43 0.0001
2024-07-29 2024-06-30 13F GUARDANT HEALTH COM 40131M109 15,942 -212,273 -93.01 460 -90.23 0.0003
2024-04-29 2024-03-31 13F GUARDANT HEALTH COM 40131M109 228,215 215,170 1,649.44 4,708 1,237.50 0.0028
2024-02-07 2023-12-31 13F GUARDANT HEALTH COM 40131M109 13,045 1,240 10.50 353 0.86 0.0002
2023-11-02 2023-09-30 13F GUARDANT HEALTH COM 40131M109 11,805 -1,323 -10.08 350 -25.59 0.0003
2023-08-07 2023-06-30 13F GUARDANT HEALTH COM 40131M109 13,128 2,718 26.11 470 92.21 0.0003
2023-05-09 2023-03-31 13F GUARDANT HEALTH COM 40131M109 10,410 -1,946 -15.75 244 -27.38 0.0002
2023-02-09 2022-12-31 13F GUARDANT HEALTH COM 40131M109 12,356 -10,817 -46.68 336 -73.06 0.0003
2022-11-09 2022-09-30 13F GUARDANT HEALTH COM 40131M109 23,173 -1,710 -6.87 1,247 24.20 0.0010
2022-08-10 2022-06-30 13F GUARDANT HEALTH COM 40131M109 24,883 7,149 40.31 1,004 -14.48 0.0007
2022-05-09 2022-03-31 13F GUARDANT HEALTH COM 40131M109 17,734 -4,167 -19.03 1,174 -46.39 0.0005
2022-05-09 2022-03-31 13F GUARDANT HEALTH COM 40131M109 20,558 1,361
2022-02-09 2021-12-31 13F GUARDANT HEALTH COM 40131M109 21,901 -7,564 -25.67 2,190 -40.55 0.0013
2021-11-09 2021-09-30 13F GUARDANT HEALTH COM 40131M109 29,465 -3,756 -11.31 3,684 -10.71 0.0024
2021-08-10 2021-06-30 13F GUARDANT HEALTH COM 40131M109 33,221 1,696 5.38 4,126 -14.27 0.0027
2021-05-10 2021-03-31 13F GUARDANT HEALTH COM 40131M109 31,525 952 3.11 4,813 22.13 0.0034
2021-02-23 2020-12-31 13F/A-1 GUARDANT HEALTH COM 40131M109 30,573 1,343 4.59 3,941 20.63 0.0029
2021-02-08 2020-12-31 13F GUARDANT HEALTH COM 40131M109 30,573 1,343 3,941 1,550.4501
2020-11-06 2020-09-30 13F GUARDANT HEALTH COM 40131M109 29,230 -2,107 -6.72 3,267 28.52 0.0027
2020-08-05 2020-06-30 13F GUARDANT HEALTH COM 40131M109 31,337 17,055 119.42 2,542 155.73 0.0023
2020-05-12 2020-03-31 13F GUARDANT HEALTH COM 40131M109 14,282 604 4.42 994 -7.02 0.0011
2020-02-05 2019-12-31 13F GUARDANT HEALTH COM 40131M109 13,678 350 2.63 1,069 25.62 0.0009
2019-11-13 2019-09-30 13F GUARDANT HEALTH COM 40131M109 13,328 -5,191 -28.03 851 -46.78 0.0008
2019-08-12 2019-06-30 13F GUARDANT HEALTH COM 40131M109 18,519 18,519 1,599 0.0014
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.