Agios Pharmaceuticals, Inc.
US ˙ NasdaqGS ˙ US00847X1046

SecurityAGIO / Agios Pharmaceuticals, Inc.
InstitutionAxa S.a.
Latest Disclosed Ownership0 shares
Latest Disclosed Value $ 0
Axa S.a. closes position in AGIO / Agios Pharmaceuticals, Inc.

On November 14, 2025 - Axa S.a. filed a 13F-HR form disclosing ownership of 0 shares of Agios Pharmaceuticals, Inc. (US:AGIO) valued at $0 USD as of September 30, 2025. The entity filed a previous 13F-HR on August 14, 2025 disclosing 225,367 shares of Agios Pharmaceuticals, Inc.. This represents a change in shares of -100.00% during the quarter. The current value of the position is $0 USD.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date		 Effective
Date		Form Security Class ID Avg Price
Paid (Est)		 Reported
Shares		 ΔShares ΔShares
(%)		 Reported
Value
(x1000)		 ΔValue
(%)		 Alloc
(%)		 ΔAlloc ΔAlloc (%) Cost Basis
(x1000)		 Unrealized
Gain/Loss
(x1000)
2025-11-14 2025-09-30 13F AGIOS PHARMACEUTICALS COM 00847X104 0 -225,367 -100.00 0 -100.00
2025-08-14 2025-06-30 13F AGIOS PHARMACEUTICALS COM 00847X104 225,367 248 0.11 7,496 13.65 0.0215
2025-05-15 2025-03-31 13F AGIOS PHARMACEUTICALS COM 00847X104 225,119 49,742 28.36 6,596 14.46 0.0217
2025-02-14 2024-12-31 13F AGIOS PHARMACEUTICALS COM 00847X104 175,377 -63,373 -26.54 5,763 -45.68 0.0175
2024-11-14 2024-09-30 13F AGIOS PHARMACEUTICALS COM 00847X104 238,750 68 0.03 10,608 3.07 0.0314
2025-02-25 2024-06-30 13F/A-1 AGIOS PHARMACEUTICALS COM 00847X104 238,682 -26,691 -10.06 10,292 32.63 0.0306
2024-08-14 2024-06-30 13F AGIOS PHARMACEUTICALS COM 00847X104 238,682 -26,691 10,292 0.0306
2024-05-15 2024-03-31 13F AGIOS PHARMACEUTICALS COM 00847X104 265,373 74 0.03 7,760 31.33 0.0233
2024-07-16 2023-12-31 13F/A-1 AGIOS PHARMACEUTICALS COM 00847X104 265,299 -6,416 -2.36 5,908 -12.14 0.0191
2024-02-14 2023-12-31 13F AGIOS PHARMACEUTICALS COM 00847X104 265,299 -6,416 5,908 0.0191
2023-11-14 2023-09-30 13F AGIOS PHARMACEUTICALS COM 00847X104 271,715 -85,351 -23.90 6,725 -33.50 0.0236
2023-08-14 2023-06-30 13F AGIOS PHARMACEUTICALS COM 00847X104 357,066 1,955 0.55 10,112 23.98 0.0336
2023-05-15 2023-03-31 13F AGIOS PHARMACEUTICALS COM 00847X104 355,111 -5,132 -1.42 8,157 -19.37 0.0281
2023-02-14 2022-12-31 13F AGIOS PHARMACEUTICALS COM 00847X104 360,243 -1,442 -0.40 10,116 -1.10 0.0365
2023-02-14 2022-09-30 13F/A-1 Agios Pharmaceuticals COM 00847X104 361,685 164,683 83.59 10,228 134.21 0.0402
2022-11-14 2022-09-30 13F Agios Pharmaceuticals COM 00847X104 361,685 164,683 10,228 0.0402
2023-02-14 2022-06-30 13F/A-1 Agios Pharmaceuticals COM 00847X104 197,002 -3,835 -1.91 4,368 -25.30 0.0162
2022-08-15 2022-06-30 13F Agios Pharmaceuticals COM 00847X104 197,002 -3,835 4,368 0.0162
2023-02-14 2022-03-31 13F/A-1 Agios Pharmaceuticals COM 00847X104 200,837 200,837 5,846 0.0166
2022-05-13 2022-03-31 13F Agios Pharmaceuticals COM 00847X104 200,837 200,837 5,846 0.0166
2021-05-14 2021-03-31 13F Agios Pharmaceuticals COM 00847X104 0 -410,189 -100.00 0 -100.00
2021-02-12 2020-12-31 13F Agios Pharmaceuticals COM 00847X104 410,189 34,773 9.26 17,773 35.26 0.0558
2021-02-11 2020-09-30 13F/A-1 Agios Pharmaceuticals COM 00847X104 375,416 63,857 20.50 13,140 -21.14 0.0475
2020-11-13 2020-09-30 13F Agios Pharmaceuticals COM 00847X104 375,416 63,857 13,140 26,229.5255
2021-02-12 2020-06-30 13F/A-1 AGIOS PHARMACEUTICALS COM 00847X104 311,559 73,189 30.70 16,662 97.02 0.0656
2020-08-14 2020-06-30 13F AGIOS PHARMACEUTICALS COM 00847X104 311,559 73,189 16,662 65,709.0285
2021-02-12 2020-03-31 13F/A-2 AGIOS PHARMACEUTICALS COM 00847X104 238,370 -38,582 -13.93 8,457 -36.05 0.0423
2020-06-15 2020-03-31 13F/A-1 AGIOS PHARMACEUTICALS COM 00847X104 238,370 0 8,457 0.0423
2020-05-15 2020-03-31 13F AGIOS PHARMACEUTICALS COM 00847X104 238,370 -38,582 8,457 23,519.0625
2021-02-12 2019-12-31 13F/A-1 AGIOS PHARMACEUTICALS COM 00847X104 276,952 40,420 17.09 13,225 72.56 0.0538
2020-02-18 2019-12-31 13F AGIOS PHARMACEUTICALS COM 00847X104 276,952 40,420 13,225 53,847.6782
2021-02-12 2019-09-30 13F/A-1 AGIOS PHARMACEUTICALS COM 00847X104 236,532 -387 -0.16 7,664 -35.15 0.0305
2019-11-14 2019-09-30 13F AGIOS PHARMACEUTICALS COM 00847X104 236,532 -387 7,664 30,541.5279
2021-02-12 2019-06-30 13F/A-1 AGIOS PHARMACEUTICALS COM 00847X104 236,919 4,766 2.05 11,818 -24.51 0.0461
2019-08-13 2019-06-30 13F AGIOS PHARMACEUTICALS COM 00847X104 236,919 4,766 11,818 46,345.2253
2019-05-14 2019-03-31 13F AGIOS PHARMACEUTICALS COM 00847X104 232,153 4,300 1.89 15,656 49.02 0.0612
2019-02-13 2018-12-31 13F AGIOS PHARMACEUTICALS COM 00847X104 227,853 23,869 11.70 10,506 -33.21 0.0458
2018-11-08 2018-09-30 13F AGIOS PHARMACEUTICALS COM 00847X104 203,984 30,368 17.49 15,731 7.57 0.0577
2018-08-13 2018-06-30 13F AGIOS PHARMACEUTICALS COM 00847X104 173,616 2,209 1.29 14,624 4.32 0.0561
2018-05-14 2018-03-31 13F AGIOS PHARMACEUTICALS COM 00847X104 171,407 -1,730 -1.00 14,018 41.62 0.0559
2018-02-13 2017-12-31 13F AGIOS PHARMACEUTICALS COM 00847X104 173,137 11,394 7.04 9,898 -8.32 0.0389
2017-12-01 2017-09-30 13F/A-1 AGIOS PHARMACEUTICALS COM 00847X104 161,743 -2,244 -1.37 10,796 27.96 0.0465
2017-11-13 2017-09-30 13F AGIOS PHARMACEUTICALS COM 00847X104 161,743 -2,244 10,796
2017-08-10 2017-06-30 13F AGIOS PHARMACEUTICALS COM 00847X104 163,987 99,683 155.02 8,437 124.69 0.0383
2017-05-11 2017-03-31 13F AGIOS PHARMACEUTICALS COM 00847X104 64,304 -1,947 -2.94 3,755 35.80 0.0170
2017-02-13 2016-12-31 13F AGIOS PHARMACEUTICALS COM 00847X104 66,251 1,260 1.94 2,765 -19.46 0.0130
2016-11-10 2016-09-30 13F AGIOS PHARMACEUTICALS COM 00847X104 64,991 24 0.04 3,433 26.12 0.0151
2016-08-11 2016-06-30 13F AGIOS PHARMACEUTICALS COM 00847X104 64,967 -2,675 -3.95 2,722 -0.87 0.0121
2016-05-13 2016-03-31 13F AGIOS PHARMACEUTICALS COM 00847X104 67,642 -1,092 -1.59 2,746 -38.46 0.0123
2016-02-12 2015-12-31 13F AGIOS PHARMACEUTICALS COM 00847X104 68,734 -4,645 -6.33 4,462 -13.86 0.0195
2015-11-13 2015-09-30 13F AGIOS PHARMACEUTICALS COM 00847X104 73,379 1,715 2.39 5,180 -34.97 0.0212
2015-08-13 2015-06-30 13F AGIOS PHARMACEUTICALS COM 00847X104 71,664 0 0.00 7,965 17.86 0.0319
2015-05-13 2015-03-31 13F AGIOS PHARMACEUTICALS COM 00847X104 71,664 5,061 7.60 6,758 -9.43 0.0279
2015-02-13 2014-12-31 13F AGIOS PHARMACEUTICALS COM 00847X104 66,603 4,262 6.84 7,462 95.08 0.0299
2014-11-13 2014-09-30 13F AGIOS PHARMACEUTICALS COM 00847X104 62,341 -400 -0.64 3,825 33.04 0.0164
2014-08-13 2014-06-30 13F AGIOS PHARMACEUTICALS COM 00847X104 62,741 0 0.00 2,875 17.06 0.0120
2014-05-13 2014-03-31 13F AGIOS PHARMACEUTICALS COM 00847X104 62,741 3,268 5.49 2,456 72.47 0.0107
2014-02-13 2013-12-31 13F AGIOS PHARMACEUTICALS COM 00847X104 59,473 59,473 1,424 0.0064
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.