Agios Pharmaceuticals, Inc.
US ˙ NasdaqGS ˙ US00847X1046

SecurityAGIO / Agios Pharmaceuticals, Inc.
InstitutionEngineers Gate Manager LP
Latest Disclosed Ownership28,920 shares
Latest Disclosed Value $ 978,364
Engineers Gate Manager LP reports 41.13% decrease in ownership of AGIO / Agios Pharmaceuticals, Inc.

On May 15, 2026 - Engineers Gate Manager LP filed a 13F-HR form disclosing ownership of 28,920 shares of Agios Pharmaceuticals, Inc. (US:AGIO) valued at $978,364 USD as of March 31, 2026. The entity filed a previous 13F-HR on February 17, 2026 disclosing 49,128 shares of Agios Pharmaceuticals, Inc.. This represents a change in shares of -41.13% during the quarter. The current value of the position is $800,506 USD.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date
Effective
Date
Form Security Class ID Avg Price
Paid (Est)
Reported
Shares
ΔShares ΔShares
(%)
Reported
Value
(x1000)
ΔValue
(%)
Alloc
(%)
ΔAlloc ΔAlloc (%) Cost Basis
(x1000)
Unrealized
Gain/Loss
(x1000)
2026-05-15 2026-03-31 13F AGIOS PHARMACEUTICALS COM 00847X104 28,920 -20,208 -41.13 978 -26.85 0.0122
2026-02-17 2025-12-31 13F AGIOS PHARMACEUTICALS COM 00847X104 49,128 49,128 1,337 0.0159
2025-11-14 2025-09-30 13F AGIOS PHARMACEUTICALS COM 00847X104 0 -16,548 -100.00 0 -100.00
2025-08-14 2025-06-30 13F AGIOS PHARMACEUTICALS COM 00847X104 16,548 -6,169 -27.16 550 -17.29 0.0068
2025-05-15 2025-03-31 13F AGIOS PHARMACEUTICALS COM 00847X104 22,717 -37,488 -62.27 666 -66.38 0.0112
2025-02-14 2024-12-31 13F AGIOS PHARMACEUTICALS COM 00847X104 60,205 36,192 150.72 1,978 85.55 0.0344
2024-11-14 2024-09-30 13F AGIOS PHARMACEUTICALS COM 00847X104 24,013 -1,793 -6.95 1,067 -4.14 0.0208
2024-08-14 2024-06-30 13F AGIOS PHARMACEUTICALS COM 00847X104 25,806 -10,764 -29.43 1,113 4.02 0.0251
2024-05-15 2024-03-31 13F AGIOS PHARMACEUTICALS COM 00847X104 36,570 11,984 48.74 1,069 95.43 0.0281
2024-02-14 2023-12-31 13F AGIOS PHARMACEUTICALS COM 00847X104 24,586 24,586 548 0.0156
2021-11-15 2021-09-30 13F AGIOS PHARMACEUTICALS COM 00847X104 0 -16,603 -100.00 0 -100.00
2021-08-16 2021-06-30 13F AGIOS PHARMACEUTICALS COM 00847X104 16,603 -231 -1.37 915 5.29 0.0588
2021-05-17 2021-03-31 13F AGIOS PHARMACEUTICALS COM 00847X104 16,834 9,934 143.97 869 190.64 0.0430
2021-02-16 2020-12-31 13F AGIOS PHARMACEUTICALS COM 00847X104 6,900 -9,198 -57.14 299 -46.89 0.0130
2020-11-16 2020-09-30 13F AGIOS PHARMACEUTICALS COM 00847X104 16,098 10,886 208.86 563 101.79 0.0264
2020-08-17 2020-06-30 13F AGIOS PHARMACEUTICALS COM 00847X104 5,212 5,212 279 0.0142
2020-05-15 2020-03-31 13F AGIOS PHARMACEUTICALS COM 00847X104 0 -18,180 -100.00 0 -100.00
2020-02-14 2019-12-31 13F AGIOS PHARMACEUTICALS COM 00847X104 18,180 3,931 27.59 868 87.88 0.0382
2019-11-14 2019-09-30 13F AGIOS PHARMACEUTICALS COM 00847X104 14,249 14,249 462 0.0235
2019-08-14 2019-06-30 13F AGIOS PHARMACEUTICALS COM 00847X104 0 -4,100 -100.00 0 -100.00
2019-05-15 2019-03-31 13F AGIOS PHARMACEUTICALS COM 00847X104 4,100 4,100 277 0.0168
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.