Agios Pharmaceuticals, Inc.
US ˙ NasdaqGS ˙ US00847X1046

SecurityAGIO / Agios Pharmaceuticals, Inc.
InstitutionFmr Llc
Latest Disclosed Ownership2,007,111 shares
Ownership 3.66%
Fmr Llc ownership in AGIO / Agios Pharmaceuticals, Inc.

2022-09-12 - Fmr Llc has filed an SC 13G/A form with the Securities and Exchange Commission (SEC) disclosing ownership of 2,007,111 shares of Agios Pharmaceuticals, Inc. (US:AGIO). This represents 3.661 percent ownership of the company. In their previous filing dated 2022-02-09 , Fmr Llc had reported owning 5,434,313 shares, indicating a decrease of -63.07 percent.

Institutional Ownership: 13D/G Filings

This table shows a history of the 13D/G filings made by the investor and/or investor group. Note that the share values in this table are not directly comparable to any numbers shown in the 13F table (if any).

File
Date
Effective
Date
Form Prev
Shares
Latest
Shares
ΔShares
(Percent)
Ownership
(Percent)
ΔOwnership
(Percent)
2022-09-12 2022-09-12 13G/A 5,434,313 2,007,111 -63.07 3.66 -63.41
2022-02-09 2022-02-09 13G/A 7,633,980 5,434,313 -28.81 10.01 -8.77
2021-03-10 2021-03-10 13G/A 4,338,666 7,633,980 75.95 10.97 75.10
2021-02-08 2021-02-08 13G/A 4,542,806 4,338,666 -4.49 6.26 -4.70
2020-08-10 2020-08-10 13G/A 8,828,462 4,542,806 -48.54 6.57 -49.10
2020-02-07 2020-02-07 13G/A 8,726,801 8,828,462 1.16 12.91 -13.91
2019-02-13 2019-02-13 13G/A 7,313,143 8,726,801 19.33 15.00 0.00
2018-02-13 2018-02-13 13G/A 6,302,216 7,313,143 16.04 15.00 0.00
2017-02-14 2017-02-14 13G/A 5,646,095 6,302,216 11.62 15.00 0.00
2016-02-12 2016-02-12 13G/A 5,646,095 15.00
2015-02-13 2015-02-13 13G/A 5,494,348 15.00
2013-11-12 2013-11-12 13G 4,503,527 14.49

Important Note: One of the primary uses of the 13D/G filings is to evaluate the ability of a firm to control a company (ie, the "beneficial ownership"). To that end, firms are required to report not just direct holdings in companies, but indirect holdings that they control. For investment firms, these indirect holdings can include shares in funds they manage, advisory accounts, and in the case of activist campaigns, pledged votes. Therefore, share counts listed in 13D/G filings can differ significantly than share counts listed in 13F filings.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date
Effective
Date
Form Security Class ID Avg Price
Paid (Est)
Reported
Shares
ΔShares ΔShares
(%)
Reported
Value
(x1000)
ΔValue
(%)
Alloc
(%)
ΔAlloc ΔAlloc (%) Cost Basis
(x1000)
Unrealized
Gain/Loss
(x1000)
2026-05-15 2026-03-31 13F AGIOS PHARMACEUTICALS COM 00847X104 9,121 -15,213 -62.52 309 -53.47 0.0000
2026-02-17 2025-12-31 13F AGIOS PHARMACEUTICALS COM 00847X104 24,334 3,622 17.49 662 -20.34 0.0000
2025-11-13 2025-09-30 13F AGIOS PHARMACEUTICALS COM 00847X104 20,712 2,120 11.40 831 34.47 0.0000
2025-08-14 2025-06-30 13F AGIOS PHARMACEUTICALS COM 00847X104 18,592 786 4.41 618 18.62 0.0000
2025-05-12 2025-03-31 13F AGIOS PHARMACEUTICALS COM 00847X104 17,806 -7,515 -29.68 522 -37.38 0.0000
2025-02-13 2024-12-31 13F AGIOS PHARMACEUTICALS COM 00847X104 25,321 -20,072 -44.22 832 -58.73 0.0000
2024-11-13 2024-09-30 13F AGIOS PHARMACEUTICALS COM 00847X104 45,393 33,546 283.16 2,017 295.29 0.0001
2024-08-13 2024-06-30 13F AGIOS PHARMACEUTICALS COM 00847X104 11,847 6,877 138.37 511 251.72 0.0000
2024-05-13 2024-03-31 13F AGIOS PHARMACEUTICALS COM 00847X104 4,970 370 8.04 145 42.16 0.0000
2024-02-13 2023-12-31 13F AGIOS PHARMACEUTICALS COM 00847X104 4,600 -694 -13.11 102 -22.14 0.0000
2023-11-13 2023-09-30 13F AGIOS PHARMACEUTICALS COM 00847X104 5,294 272 5.42 131 -7.75 0.0000
2023-08-11 2023-06-30 13F AGIOS PHARMACEUTICALS COM 00847X104 5,022 -27 -0.53 142 23.48 0.0000
2023-08-11 2023-03-31 13F/A-1 AGIOS PHARMACEUTICALS COM 00847X104 5,049 -1,635,265 -99.69 116 -99.75 0.0000
2023-05-11 2023-03-31 13F AGIOS PHARMACEUTICALS COM 00847X104 5,049 -1,635,265 116 0.0000
2023-02-13 2022-12-31 13F AGIOS PHARMACEUTICALS COM 00847X104 1,640,314 -266,240 -13.96 46,060 -14.58 0.0046
2022-11-10 2022-09-30 13F AGIOS PHARMACEUTICALS COM 00847X104 1,906,554 -1,029,288 -35.06 53,919 -17.16 0.0056
2022-08-12 2022-06-30 13F AGIOS PHARMACEUTICALS COM 00847X104 2,935,842 -1,882,650 -39.07 65,088 -53.60 0.0065
2022-05-13 2022-03-31 13F AGIOS PHARMACEUTICALS COM 00847X104 4,818,492 -615,822 -11.33 140,266 -21.48 0.0112
2022-02-14 2021-12-31 13F AGIOS PHARMACEUTICALS COM 00847X104 5,434,314 -1,414,504 -20.65 178,626 -43.49 0.0132
2022-02-14 2021-09-30 13F/A-1 AGIOS PHARMACEUTICALS COM 00847X104 6,848,818 -1,233,192 -15.26 316,074 -29.04 0.0251
2021-11-15 2021-09-30 13F AGIOS PHARMACEUTICALS COM 00847X104 6,848,818 -1,233,192 316,074 0.0251
2021-08-13 2021-06-30 13F AGIOS PHARMACEUTICALS COM 00847X104 8,082,010 203,105 2.58 445,400 9.47 0.0349
2021-05-14 2021-03-31 13F AGIOS PHARMACEUTICALS COM 00847X104 7,878,905 3,540,238 81.60 406,867 116.43 0.0347
2021-02-08 2020-12-31 13F AGIOS PHARMACEUTICALS COM 00847X104 4,338,667 509,781 13.31 187,994 40.28 0.0167
2020-11-13 2020-09-30 13F AGIOS PHARMACEUTICALS COM 00847X104 3,828,886 -1,787,441 -31.83 134,011 -55.38 0.0135
2020-08-24 2020-06-30 13F/A-1 AGIOS PHARMACEUTICALS COM 00847X104 5,616,327 -3,379,252 -37.57 300,361 -5.89 0.0330
2020-08-13 2020-06-30 13F AGIOS PHARMACEUTICALS COM 00847X104 5,616,327 -3,379,252 300,361 7,378.9908
2020-05-14 2020-03-31 13F AGIOS PHARMACEUTICALS COM 00847X104 8,995,579 167,117 1.89 319,163 -24.29 0.0442
2020-02-07 2019-12-31 13F AGIOS PHARMACEUTICALS COM 00847X104 8,828,462 15,530 0.18 421,559 47.64 0.0465
2019-11-13 2019-09-30 13F AGIOS PHARMACEUTICALS COM 00847X104 8,812,932 6,232 0.07 285,539 -35.00 0.0342
2019-08-13 2019-06-30 13F AGIOS PHARMACEUTICALS COM 00847X104 8,806,700 47,387 0.54 439,278 -25.64 0.0513
2019-05-13 2019-03-31 13F AGIOS PHARMACEUTICALS COM 00847X104 8,759,313 32,512 0.37 590,728 46.80 0.0708
2019-02-13 2018-12-31 13F AGIOS PHARMACEUTICALS COM 00847X104 8,726,801 27,915 0.32 402,393 -40.02 0.0551
2018-11-09 2018-09-30 13F AGIOS PHARMACEUTICALS COM 00847X104 8,698,886 58,043 0.67 670,858 -7.83 0.0755
2018-08-10 2018-06-30 13F AGIOS PHARMACEUTICALS COM 00847X104 8,640,843 41,832 0.49 727,818 3.50 0.0859
2018-05-14 2018-03-31 13F AGIOS PHARMACEUTICALS COM 00847X104 8,599,011 1,289,268 17.64 703,227 68.28 0.0835
2018-02-12 2017-12-31 13F AGIOS PHARMACEUTICALS COM 00847X104 7,309,743 51,064 0.70 417,898 -13.75 0.0490
2017-11-13 2017-09-30 13F AGIOS PHARMACEUTICALS COM 00847X104 7,258,679 31,348 0.43 484,517 30.30 0.0586
2017-08-29 2017-06-30 13F/A-1 AGIOS PHARMACEUTICALS COM 00847X104 7,227,331 895,584 14.14 371,846 0.56 0.0462
2017-08-11 2017-06-30 13F AGIOS PHARMACEUTICALS COM 00847X104 7,227,331 895,584 371,846
2017-05-11 2017-03-31 13F AGIOS PHARMACEUTICALS COM 00847X104 6,331,747 32,931 0.52 369,774 40.68 0.0470
2017-02-10 2016-12-31 13F AGIOS PHARMACEUTICALS COM 00847X104 6,298,816 87,744 1.41 262,849 -19.88 0.0351
2016-11-14 2016-09-30 13F AGIOS PHARMACEUTICALS COM 00847X104 6,211,072 526,304 9.26 328,069 37.75 0.0437
2016-08-11 2016-06-30 13F AGIOS PHARMACEUTICALS COM 00847X104 5,684,768 10,684 0.19 238,163 3.38 0.0325
2016-05-16 2016-03-31 13F AGIOS PHARMACEUTICALS COM 00847X104 5,674,084 27,989 0.50 230,368 -37.15 0.0319
2016-02-12 2015-12-31 13F AGIOS PHARMACEUTICALS COM 00847X104 5,646,095 29,542 0.53 366,544 -7.55 0.0493
2015-11-10 2015-09-30 13F AGIOS PHARMACEUTICALS COM 00847X104 5,616,553 21,828 0.39 396,472 -36.24 0.0564
2015-08-25 2015-06-30 13F/A-1 AGIOS PHARMACEUTICALS COM 00847X104 5,594,725 11,957 0.21 621,798 18.11 0.0797
2015-08-13 2015-06-30 13F AGIOS PHARMACEUTICALS COM 00847X104 5,594,725 621,798
2015-05-14 2015-03-31 13F AGIOS PHARMACEUTICALS COM 00847X104 5,582,768 88,420 1.61 526,455 -14.48 0.0671
2015-02-17 2014-12-31 13F AGIOS PHARMACEUTICALS COM 00847X104 5,494,348 243,889 4.65 615,587 91.11 0.0801
2014-11-14 2014-09-30 13F AGIOS PHARMACEUTICALS COM 00847X104 5,250,459 158,813 3.12 322,116 38.07 0.0436
2014-08-14 2014-06-30 13F AGIOS PHARMACEUTICALS COM 00847X104 5,091,646 1,450,967 39.85 233,299 63.68 0.0313
2014-05-15 2014-03-31 13F AGIOS PHARMACEUTICALS COM 00847X104 3,640,679 1,409,114 63.14 142,533 166.69 0.0198
2014-02-13 2013-12-31 13F AGIOS PHARMACEUTICALS COM 00847X104 2,231,565 0 0.00 53,446 -14.34 0.0076
2013-11-14 2013-09-30 13F AGIOS PHARMACEUTICALS COM 00847X104 2,231,565 2,231,565 62,395 0.0096
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.