Agios Pharmaceuticals, Inc.
US ˙ NasdaqGS ˙ US00847X1046

SecurityAGIO / Agios Pharmaceuticals, Inc.
InstitutionMacquarie Group Ltd
Latest Disclosed Ownership0 shares
Latest Disclosed Value $ 0
Macquarie Group Ltd closes position in AGIO / Agios Pharmaceuticals, Inc.

On February 13, 2026 - Macquarie Group Ltd filed a 13F-HR form disclosing ownership of 0 shares of Agios Pharmaceuticals, Inc. (US:AGIO) valued at $0 USD as of December 31, 2025. The entity filed a previous 13F-HR on November 13, 2025 disclosing 1,958,101 shares of Agios Pharmaceuticals, Inc.. The current value of the position is $0 USD.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date		 Effective
Date		Form Security Class ID Avg Price
Paid (Est)		 Reported
Shares		 ΔShares ΔShares
(%)		 Reported
Value
(x1000)		 ΔValue
(%)		 Alloc
(%)		 ΔAlloc ΔAlloc (%) Cost Basis
(x1000)		 Unrealized
Gain/Loss
(x1000)
2026-02-13 2025-12-31 13F AGIOS PHARMACEUTICALS COM 00847X104 0 -100.00 0
2025-11-13 2025-09-30 13F AGIOS PHARMACEUTICALS COM 00847X104 1,958,101 57,505 3.03 78,598 24.34 0.0917
2025-08-14 2025-06-30 13F AGIOS PHARMACEUTICALS COM 00847X104 1,900,596 50,052 2.70 63,214 16.59 0.0775
2025-08-14 2025-03-31 13F/A-1 AGIOS PHARMACEUTICALS COM 00847X104 1,850,544 165,551 9.83 54,221 -2.07 0.0673
2025-05-15 2025-03-31 13F AGIOS PHARMACEUTICALS COM 00847X104 1,850,544 165,551 54,221 0.0443
2025-02-14 2024-12-31 13F AGIOS PHARMACEUTICALS COM 00847X104 1,684,993 -5,808 -0.34 55,369 -26.29 0.0672
2024-11-14 2024-09-30 13F AGIOS PHARMACEUTICALS COM 00847X104 1,690,801 -38,928 -2.25 75,122 0.72 0.0811
2024-08-09 2024-06-30 13F AGIOS PHARMACEUTICALS COM 00847X104 1,729,729 -229,928 -11.73 74,586 30.17 0.0855
2024-05-14 2024-03-31 13F AGIOS PHARMACEUTICALS COM 00847X104 1,959,657 -55,757 -2.77 57,300 27.67 0.0650
2024-02-14 2023-12-31 13F AGIOS PHARMACEUTICALS COM 00847X104 2,015,414 23,392 1.17 44,883 -8.96 0.0518
2023-11-14 2023-09-30 13F AGIOS PHARMACEUTICALS COM 00847X104 1,992,022 365,062 22.44 49,303 7.00 0.0619
2023-10-27 2023-06-30 13F/A-2 AGIOS PHARMACEUTICALS COM 00847X104 1,626,960 179,572 12.41 46,076 38.59 0.0527
2023-10-12 2023-06-30 13F/A-1 AGIOS PHARMACEUTICALS COM 00847X104 1,626,960 179,572 46,076 0.0463
2023-08-14 2023-06-30 13F AGIOS PHARMACEUTICALS COM 00847X104 1,626,960 179,572 46,076 0.0467
2023-06-01 2023-03-31 13F/A-1 AGIOS PHARMACEUTICALS COM 00847X104 1,447,388 34,979 2.48 33,247 -16.17 0.0395
2023-05-15 2023-03-31 13F AGIOS PHARMACEUTICALS COM 00847X104 1,447,388 34,979 33,247 0.0305
2023-02-21 2022-12-31 13F AGIOS PHARMACEUTICALS COM 00847X104 1,412,409 36,170 2.63 39,660 1.86 0.0468
2022-11-14 2022-09-30 13F AGIOS PHARMACEUTICALS COM 00847X104 1,376,239 24,128 1.78 38,934 29.88 0.0478
2022-08-17 2022-06-30 13F/A-1 AGIOS PHARMACEUTICALS COM 00847X104 1,352,111 -112,821 -7.70 29,976 -29.71 0.0337
2022-08-15 2022-06-30 13F AGIOS PHARMACEUTICALS COM 00847X104 1,352,111 -112,821 29,976 0.0107
2022-05-16 2022-03-31 13F AGIOS PHARMACEUTICALS COM 00847X104 1,464,932 300,948 25.85 42,644 11.46 0.0324
2022-02-11 2021-12-31 13F Agios Pharmaceuticals COM 00847X104 1,163,984 8,624 0.75 38,260 -28.24 0.0319
2021-11-12 2021-09-30 13F AGIOS PHARMACEUTICALS COM 00847X104 1,155,360 636 0.06 53,320 -16.21 0.0454
2021-08-13 2021-06-30 13F AGIOS PHARMACEUTICALS COM 00847X104 1,154,724 18,467 1.63 63,637 8.45 0.0523
2021-05-14 2021-03-31 13F AGIOS PHARMACEUTICALS COM 00847X104 1,136,257 40,310 3.68 58,676 23.56 0.0830
2021-02-16 2020-12-31 13F AGIOS PHARMACEUTICALS COM 00847X104 1,095,947 -138,188 -11.20 47,487 9.94 0.0693
2020-11-13 2020-09-30 13F AGIOS PHARMACEUTICALS COM 00847X104 1,234,135 4,785 0.39 43,194 -34.30 0.0731
2020-08-11 2020-06-30 13F AGIOS PHARMACEUTICALS COM 00847X104 1,229,350 99,333 8.79 65,746 63.99 0.1132
2020-05-15 2020-03-31 13F AGIOS PHARMACEUTICALS COM 00847X104 1,130,017 85,890 8.23 40,092 -19.59 0.0824
2020-03-18 2019-12-31 13F/A-2 AGIOS PHARMACEUTICALS COM 00847X104 1,044,127 200,097 23.71 49,857 82.31 0.0712
2020-02-28 2019-12-31 13F/A-1 AGIOS PHARMACEUTICALS COM 00847X104 1,044,127 0 49,857 0.0720
2020-02-14 2019-12-31 13F AGIOS PHARMACEUTICALS COM 00847X104 1,044,127 200,097 49,857 62,566.3097
2019-11-14 2019-09-30 13F AGIOS PHARMACEUTICALS COM 00847X104 844,030 844,030 27,347 0.0458
2018-02-14 2017-12-31 13F AGIOS PHARMACEUTICALS COM 00847X104 0 -3,675 -100.00 0 -100.00
2017-11-08 2017-09-30 13F AGIOS PHARMACEUTICALS COM 00847X104 3,675 3,675 245 0.0004
2016-08-15 2016-06-30 13F AGIOS PHARMACEUTICALS COMMON 00847X104 0 -16,644 -100.00 0 -100.00
2016-05-16 2016-03-31 13F AGIOS PHARMACEUTICALS COMMON 00847X104 16,644 -15,574 -48.34 676 -67.69 0.0014
2016-02-16 2015-12-31 13F AGIOS PHARMACEUTICALS COMMON 00847X104 32,218 4,331 15.53 2,092 6.25 0.0043
2015-11-16 2015-09-30 13F AGIOS PHARMACEUTICALS COMMON 00847X104 27,887 692 2.54 1,969 -34.84 0.0042
2015-08-21 2015-06-30 13F/A-1 AGIOS PHARMACEUTICALS COMMON 00847X104 27,195 5,100 23.08 3,022 45.01 0.0060
2015-08-14 2015-06-30 13F AGIOS PHARMACEUTICALS COMMON 00847X104 27,195 3,022
2015-05-18 2015-03-31 13F AGIOS PHARMACEUTICALS COMMON 00847X104 22,095 9,251 72.03 2,084 44.82 0.0041
2015-02-17 2014-12-31 13F AGIOS PHARMACEUTICALS COMMON 00847X104 12,844 12,844 1,439 0.0030
2014-08-14 2014-06-30 13F AGIOS PHARMACEUTICALS Common 00847X104 0 -2,411 -100.00 0 -100.00
2014-05-15 2014-03-31 13F AGIOS PHARMACEUTICALS Common 00847X104 2,411 2,411 94 0.0002
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.