AnaptysBio, Inc.
US ˙ NasdaqGS ˙ US0327241065

SecurityANAB / AnaptysBio, Inc.
InstitutionSquarepoint Ops LLC
Latest Disclosed Ownership267,703 shares
Latest Disclosed Value $ 14,846,808
Squarepoint Ops LLC reports 66.55% increase in ownership of ANAB / AnaptysBio, Inc.

On May 15, 2026 - Squarepoint Ops LLC filed a 13F-HR form disclosing ownership of 267,703 shares of AnaptysBio, Inc. (US:ANAB) valued at $14,846,808 USD as of March 31, 2026. The entity filed a previous 13F-HR on February 13, 2026 disclosing 160,731 shares of AnaptysBio, Inc.. This represents a change in shares of 66.55% during the quarter. The current value of the position is $13,717,102 USD.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

Upgrade to unlock premium data and export to Excel .

Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date		 Effective
Date		Form Security Class ID Avg Price
Paid (Est)		 Reported
Shares		 ΔShares ΔShares
(%)		 Reported
Value
(x1000)		 ΔValue
(%)		 Alloc
(%)		 ΔAlloc ΔAlloc (%) Cost Basis
(x1000)		 Unrealized
Gain/Loss
(x1000)
2026-05-15 2026-03-31 13F ANAPTYSBIO COM 032724106 267,703 106,972 66.55 14,847 90.53 0.0174
2026-02-13 2025-12-31 13F ANAPTYSBIO COM 032724106 160,731 92,717 136.32 7,792 274.26 0.0083
2025-11-14 2025-09-30 13F ANAPTYSBIO COM 032724106 68,014 -41,374 -37.82 2,083 -14.25 0.0021
2025-08-27 2025-06-30 13F/A-1 ANAPTYSBIO COM 032724106 109,388 109,388 2,428 0.0025
2025-08-14 2025-06-30 13F ANAPTYSBIO COM 032724106 109,388 109,388 2,428 0.0025
2025-08-27 2025-03-31 13F/A-1 ANAPTYSBIO COM 032724106 0 -80,870 -100.00 0 -100.00
2025-05-15 2025-03-31 13F ANAPTYSBIO COM 032724106 0 -80,870 0
2025-02-14 2024-12-31 13F ANAPTYSBIO COM 032724106 80,870 36,365 81.71 1,071 -28.19 0.0011
2024-11-14 2024-09-30 13F ANAPTYSBIO COM 032724106 44,505 33,320 297.90 1,491 432.14 0.0023
2024-08-14 2024-06-30 13F ANAPTYSBIO COM 032724106 11,185 -482 -4.13 280 6.87 0.0005
2024-05-15 2024-03-31 13F ANAPTYSBIO COM 032724106 11,667 -6,256 -34.90 263 -31.59 0.0005
2024-02-14 2023-12-31 13F ANAPTYSBIO COM 032724106 17,923 -34,530 -65.83 384 -59.34 0.0007
2023-11-14 2023-09-30 13F ANAPTYSBIO COM 032724106 52,453 20,968 66.60 942 47.19 0.0023
2023-08-14 2023-06-30 13F ANAPTYSBIO COM 032724106 31,485 1,383 4.59 640 -2.29 0.0020
2023-05-15 2023-03-31 13F ANAPTYSBIO COM 032724106 30,102 13,319 79.36 655 25.96 0.0027
2023-02-14 2022-12-31 13F ANAPTYSBIO COM 032724106 16,783 -21,926 -56.64 520 -47.32 0.0021
2022-11-14 2022-09-30 13F ANAPTYSBIO COM 032724106 38,709 -9,202 -19.21 987 1.44 0.0050
2022-08-15 2022-06-30 13F ANAPTYSBIO COM 032724106 47,911 47,911 973 0.0054
2021-02-16 2020-12-31 13F ANAPTYSBIO COM 032724106 0 -20,473 -100.00 0 -100.00
2020-11-16 2020-09-30 13F ANAPTYSBIO COM 032724106 20,473 20,473 302 0.0041
2020-08-14 2020-06-30 13F ANAPTYSBIO COM 032724106 0 -13,086 -100.00 0 -100.00
2020-05-15 2020-03-31 13F ANAPTYSBIO COM 032724106 13,086 -2,307 -14.99 185 -26.00 0.0047
2020-02-14 2019-12-31 13F ANAPTYSBIO COM 032724106 15,393 3,608 30.62 250 -39.32 0.0015
2019-11-14 2019-09-30 13F ANAPTYSBIO COM 032724106 11,785 2,475 26.58 412 -21.52 0.0037
2019-08-14 2019-06-30 13F ANAPTYSBIO COM 032724106 9,310 -8,290 -47.10 525 -59.18 0.0051
2019-05-15 2019-03-31 13F ANAPTYSBIO COM 032724106 17,600 7,736 78.43 1,286 104.45 0.0136
2019-02-14 2018-12-31 13F ANAPTYSBIO COM 032724106 9,864 -8,190 -45.36 629 -65.07 0.0073
2018-11-14 2018-09-30 13F ANAPTYSBIO COM 032724106 18,054 3,454 23.66 1,801 73.67 0.0216
2018-08-14 2018-06-30 13F ANAPTYSBIO COM 032724106 14,600 12,300 534.78 1,037 333.89 0.0137
2018-05-15 2018-03-31 13F ANAPTYSBIO COM 032724106 2,300 -6,313 -73.30 239 -72.47 0.0038
2018-02-14 2017-12-31 13F ANAPTYSBIO COM 032724106 8,613 8,613 868 0.0151
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.