Annexon, Inc.
US ˙ NasdaqGS ˙ US03589W1027

SecurityANNX / Annexon, Inc.
InstitutionDeerfield Management Company, L.p. (series C)
Latest Disclosed Ownership583,913 shares
Latest Disclosed Value $ 3,234,878
Deerfield Management Company, L.p. (series C) ownership in ANNX / Annexon, Inc.

On May 15, 2026 - Deerfield Management Company, L.p. (series C) filed a 13F-HR form disclosing ownership of 583,913 shares of Annexon, Inc. (US:ANNX) valued at $3,234,878 USD as of March 31, 2026. The entity filed a previous 13F-HR on February 17, 2026 disclosing 583,913 shares of Annexon, Inc.. This represents a change in shares of 0.00% during the quarter. The current value of the position is $3,147,291 USD.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date
Effective
Date
Form Security Class ID Avg Price
Paid (Est)
Reported
Shares
ΔShares ΔShares
(%)
Reported
Value
(x1000)
ΔValue
(%)
Alloc
(%)
ΔAlloc ΔAlloc (%) Cost Basis
(x1000)
Unrealized
Gain/Loss
(x1000)
2026-05-15 2026-03-31 13F ANNEXON COM 03589W102 583,913 0 0.00 3,235 10.34 0.0382
2026-02-17 2025-12-31 13F ANNEXON COM 03589W102 583,913 0 0.00 2,931 64.66 0.0374
2025-11-14 2025-09-30 13F ANNEXON COM 03589W102 583,913 0 0.00 1,781 27.05 0.0272
2025-08-14 2025-06-30 13F ANNEXON COM 03589W102 583,913 0 0.00 1,401 24.42 0.0254
2025-05-15 2025-03-31 13F ANNEXON COM 03589W102 583,913 0 0.00 1,127 -62.40 0.0223
2025-02-14 2024-12-31 13F ANNEXON COM 03589W102 583,913 0 0.00 2,995 -13.34 0.0567
2024-11-14 2024-09-30 13F ANNEXON COM 03589W102 583,913 0 0.00 3,457 20.80 0.0516
2024-08-14 2024-06-30 13F ANNEXON COM 03589W102 583,913 0 0.00 2,861 -31.65 0.0476
2024-05-15 2024-03-31 13F ANNEXON COM 03589W102 583,913 0 0.00 4,187 57.96 0.0728
2024-02-14 2023-12-31 13F ANNEXON COM 03589W102 583,913 0 0.00 2,651 92.31 0.0490
2023-11-14 2023-09-30 13F ANNEXON COM 03589W102 583,913 0 0.00 1,378 -32.94 0.0304
2023-08-14 2023-06-30 13F ANNEXON COM 03589W102 583,913 0 0.00 2,055 -8.59 0.0439
2023-05-15 2023-03-31 13F ANNEXON COM 03589W102 583,913 0 0.00 2,248 -25.51 0.0501
2023-02-14 2022-12-31 13F ANNEXON COM 03589W102 583,913 0 0.00 3,019 -16.38 0.0625
2022-11-14 2022-09-30 13F ANNEXON COM 03589W102 583,913 0 0.00 3,609 63.97 0.0718
2022-08-15 2022-06-30 13F ANNEXON COM 03589W102 583,913 0 0.00 2,201 38.08 0.0454
2022-05-16 2022-03-31 13F ANNEXON COM 03589W102 583,913 0 0.00 1,594 -76.24 0.0356
2022-02-14 2021-12-31 13F ANNEXON COM 03589W102 583,913 0 0.00 6,709 -38.26 0.1407
2021-11-15 2021-09-30 13F ANNEXON COM 03589W102 583,913 0 0.00 10,867 -17.32 0.2121
2021-08-16 2021-06-30 13F ANNEXON COM 03589W102 583,913 0 0.00 13,144 -19.14 0.2335
2021-05-17 2021-03-31 13F ANNEXON COM 03589W102 583,913 -583,913 -50.00 16,256 -44.39 0.3416
2021-02-16 2020-12-31 13F ANNEXON COM 03589W102 1,167,826 -450,000 -27.82 29,231 -40.23 0.5777
2020-12-30 2020-09-30 13F/A-1 ANNEXON COM 03589W102 1,617,826 1,617,826 48,907 1.1908
2020-11-16 2020-09-30 13F ANNEXON COM 03589W102 1,617,826 1,617,826 48,907 1.1908
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.