Apogee Therapeutics, Inc.
US ˙ NasdaqGM ˙ US03770N1019

SecurityAPGE / Apogee Therapeutics, Inc.
InstitutionDriehaus Capital Management Llc
Latest Disclosed Ownership2,158,502 shares
Ownership 4.68%
Driehaus Capital Management Llc ownership in APGE / Apogee Therapeutics, Inc.

2025-11-14 - Driehaus Capital Management Llc has filed an SCHEDULE 13G/A form with the Securities and Exchange Commission (SEC) disclosing ownership of 2,158,502 shares of Apogee Therapeutics, Inc. (US:APGE). This represents 4.68 percent ownership of the company. In their previous filing dated 2024-11-14 , Driehaus Capital Management Llc had reported owning 2,533,607 shares, indicating a decrease of -14.81 percent.

Institutional Ownership: 13D/G Filings

This table shows a history of the 13D/G filings made by the investor and/or investor group. Note that the share values in this table are not directly comparable to any numbers shown in the 13F table (if any).

File
Date
Effective
Date
Form Prev
Shares
Latest
Shares
ΔShares
(Percent)
Ownership
(Percent)
ΔOwnership
(Percent)
2025-11-14 2025-11-14 13G/A 2,533,607 2,158,502 -14.81 4.68 -16.87
2024-11-14 2024-11-14 13G 2,533,607 5.63

Important Note: One of the primary uses of the 13D/G filings is to evaluate the ability of a firm to control a company (ie, the "beneficial ownership"). To that end, firms are required to report not just direct holdings in companies, but indirect holdings that they control. For investment firms, these indirect holdings can include shares in funds they manage, advisory accounts, and in the case of activist campaigns, pledged votes. Therefore, share counts listed in 13D/G filings can differ significantly than share counts listed in 13F filings.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date
Effective
Date
Form Security Class ID Avg Price
Paid (Est)
Reported
Shares
ΔShares ΔShares
(%)
Reported
Value
(x1000)
ΔValue
(%)
Alloc
(%)
ΔAlloc ΔAlloc (%) Cost Basis
(x1000)
Unrealized
Gain/Loss
(x1000)
2026-05-15 2026-03-31 13F Apogee Therapeutics COM 03770N101 1,920,800 -262,904 -12.04 161,674 -1.91 1.1844
2026-02-17 2025-12-31 13F Apogee Therapeutics COM 03770N101 2,183,704 25,202 1.17 164,826 92.20 1.1196
2025-11-14 2025-09-30 13F APOGEE THERAPEUTICS COM 03770N101 2,158,502 -152,253 -6.59 85,757 -14.55 0.6142
2025-08-14 2025-06-30 13F APOGEE THERAPEUTICS COM 03770N101 2,310,755 -28,808 -1.23 100,356 14.82 0.8030
2025-05-15 2025-03-31 13F APOGEE THERAPEUTICS COM 03770N101 2,339,563 -265,747 -10.20 87,406 -25.94 0.8425
2025-02-14 2024-12-31 13F APOGEE THERAPEUTICS COM 03770N101 2,605,310 71,703 2.83 118,021 -20.70 0.9740
2024-11-14 2024-09-30 13F APOGEE THERAPEUTICS COM 03770N101 2,533,607 415,737 19.63 148,824 78.58 1.2776
2024-08-15 2024-06-30 13F/A-1 APOGEE THERAPEUTICS COM 03770N101 2,117,870 54,107 2.62 83,338 -39.23 0.8062
2024-08-14 2024-06-30 13F APOGEE THERAPEUTICS COM 03770N101 2,117,870 54,107 83,338 0.8035
2024-05-15 2024-03-31 13F APOGEE THERAPEUTICS COM 03770N101 2,063,763 734,699 55.28 137,137 269.30 1.3662
2024-02-14 2023-12-31 13F APOGEE THERAPEUTICS COM 03770N101 1,329,064 -10,211 -0.76 37,134 30.18 0.4474
2023-11-14 2023-09-30 13F APOGEE THERAPEUTICS COM 03770N101 1,339,275 1,339,275 28,527 0.3708
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.