Apellis Pharmaceuticals, Inc.
US ˙ NasdaqGS ˙ US03753U1060
DIESES SYMBOL IST NICHT MEHR AKTIV

SecurityAPLS / Apellis Pharmaceuticals, Inc.
InstitutionFmr Llc
Latest Disclosed Ownership5,563 shares
Latest Disclosed Value $ 223,797
Fmr Llc reports 82.70% decrease in ownership of APLS / Apellis Pharmaceuticals, Inc.

On May 15, 2026 - Fmr Llc filed a 13F-HR form disclosing ownership of 5,563 shares of Apellis Pharmaceuticals, Inc. (US:APLS) valued at $223,799 USD as of March 31, 2026. The entity filed a previous 13F-HR on February 17, 2026 disclosing 32,163 shares of Apellis Pharmaceuticals, Inc.. This represents a change in shares of -82.70% during the quarter. The current value of the position is $228,250 USD.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

Upgrade to unlock premium data and export to Excel .

Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date		 Effective
Date		Form Security Class ID Avg Price
Paid (Est)		 Reported
Shares		 ΔShares ΔShares
(%)		 Reported
Value
(x1000)		 ΔValue
(%)		 Alloc
(%)		 ΔAlloc ΔAlloc (%) Cost Basis
(x1000)		 Unrealized
Gain/Loss
(x1000)
2026-05-15 2026-03-31 13F APELLIS PHARMACEUTICALS COM 03753U106 5,563 -26,600 -82.70 224 -72.37 0.0000
2026-02-17 2025-12-31 13F APELLIS PHARMACEUTICALS COM 03753U106 32,163 13,660 73.83 808 93.06 0.0000
2025-11-13 2025-09-30 13F APELLIS PHARMACEUTICALS COM 03753U106 18,503 -789 -4.09 419 25.53 0.0000
2025-08-14 2025-06-30 13F APELLIS PHARMACEUTICALS COM 03753U106 19,292 -1,483,917 -98.72 334 -98.99 0.0000
2025-05-12 2025-03-31 13F APELLIS PHARMACEUTICALS COM 03753U106 1,503,209 -624,456 -29.35 32,875 -51.58 0.0021
2025-02-13 2024-12-31 13F APELLIS PHARMACEUTICALS COM 03753U106 2,127,665 -772,589 -26.64 67,894 -18.83 0.0041
2024-11-13 2024-09-30 13F APELLIS PHARMACEUTICALS COM 03753U106 2,900,254 -399,536 -12.11 83,643 -33.92 0.0051
2024-08-13 2024-06-30 13F APELLIS PHARMACEUTICALS COM 03753U106 3,299,790 1,121,048 51.45 126,580 -1.16 0.0081
2024-05-13 2024-03-31 13F APELLIS PHARMACEUTICALS COM 03753U106 2,178,742 86,278 4.12 128,066 2.25 0.0086
2024-02-13 2023-12-31 13F APELLIS PHARMACEUTICALS COM 03753U106 2,092,464 -167,302 -7.40 125,255 45.71 0.0096
2023-11-13 2023-09-30 13F APELLIS PHARMACEUTICALS COM 03753U106 2,259,766 -1,965,829 -46.52 85,961 -77.67 0.0074
2023-08-11 2023-06-30 13F APELLIS PHARMACEUTICALS COM 03753U106 4,225,595 2,100,158 98.81 384,952 174.59 0.0323
2023-08-11 2023-03-31 13F/A-1 APELLIS PHARMACEUTICALS COM 03753U106 2,125,437 665,274 45.56 140,194 85.67 0.0128
2023-05-11 2023-03-31 13F APELLIS PHARMACEUTICALS COM 03753U106 2,125,437 665,274 140,194 0.0128
2023-02-13 2022-12-31 13F APELLIS PHARMACEUTICALS COM 03753U106 1,460,163 -1 -0.00 75,505 -24.29 0.0075
2022-11-10 2022-09-30 13F APELLIS PHARMACEUTICALS COM 03753U106 1,460,164 71,737 5.17 99,729 58.84 0.0104
2022-08-12 2022-06-30 13F APELLIS PHARMACEUTICALS COM 03753U106 1,388,427 -9,165 -0.66 62,784 -11.59 0.0063
2022-05-13 2022-03-31 13F APELLIS PHARMACEUTICALS COM 03753U106 1,397,592 -217,267 -13.45 71,012 -6.99 0.0057
2022-02-14 2021-12-31 13F APELLIS PHARMACEUTICALS COM 03753U106 1,614,859 0 0.00 76,351 43.45 0.0056
2022-02-14 2021-09-30 13F/A-1 APELLIS PHARMACEUTICALS COM 03753U106 1,614,859 143,694 9.77 53,226 -42.75 0.0042
2021-11-15 2021-09-30 13F APELLIS PHARMACEUTICALS COM 03753U106 1,614,859 143,694 53,226 0.0042
2021-08-13 2021-06-30 13F APELLIS PHARMACEUTICALS COM 03753U106 1,471,165 -150,087 -9.26 92,978 33.65 0.0073
2021-05-14 2021-03-31 13F APELLIS PHARMACEUTICALS COM 03753U106 1,621,252 481,526 42.25 69,568 6.71 0.0059
2021-02-08 2020-12-31 13F APELLIS PHARMACEUTICALS COM 03753U106 1,139,726 871,592 325.06 65,192 705.83 0.0058
2020-11-13 2020-09-30 13F APELLIS PHARMACEUTICALS COM 03753U106 268,134 -230,088 -46.18 8,090 -50.28 0.0008
2020-08-24 2020-06-30 13F/A-1 APELLIS PHARMACEUTICALS COM 03753U106 498,222 -20,312 -3.92 16,272 17.13 0.0018
2020-08-13 2020-06-30 13F APELLIS PHARMACEUTICALS COM 03753U106 498,222 -20,312 16,272 399.7554
2020-05-14 2020-03-31 13F APELLIS PHARMACEUTICALS COM 03753U106 518,534 -20,900 -3.87 13,892 -15.89 0.0019
2020-02-07 2019-12-31 13F APELLIS PHARMACEUTICALS COM 03753U106 539,434 166,300 44.57 16,517 83.75 0.0018
2019-11-13 2019-09-30 13F APELLIS PHARMACEUTICALS COM 03753U106 373,134 10,000 2.75 8,989 -2.31 0.0011
2019-08-13 2019-06-30 13F APELLIS PHARMACEUTICALS COM 03753U106 363,134 -294 -0.08 9,202 29.84 0.0011
2019-05-13 2019-03-31 13F APELLIS PHARMACEUTICALS COM 03753U106 363,428 -106,400 -22.65 7,087 14.36 0.0008
2019-02-13 2018-12-31 13F APELLIS PHARMACEUTICALS COM 03753U106 469,828 -97,500 -17.19 6,197 -38.56 0.0008
2018-11-09 2018-09-30 13F APELLIS PHARMACEUTICALS COM 03753U106 567,328 -775,812 -57.76 10,087 -65.86 0.0011
2018-08-10 2018-06-30 13F APELLIS PHARMACEUTICALS COM 03753U106 1,343,140 345,376 34.61 29,549 33.94 0.0035
2018-05-14 2018-03-31 13F APELLIS PHARMACEUTICALS COM 03753U106 997,764 693,847 228.30 22,061 234.51 0.0026
2018-02-12 2017-12-31 13F APELLIS PHARMACEUTICALS COM 03753U106 303,917 303,917 6,595 0.0008
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.