Apellis Pharmaceuticals, Inc.
US ˙ NasdaqGS ˙ US03753U1060
DIESES SYMBOL IST NICHT MEHR AKTIV

SecurityAPLS / Apellis Pharmaceuticals, Inc.
InstitutionSei Investments Co
Latest Disclosed Ownership60,291 shares
Latest Disclosed Value $ 1,514,550
Sei Investments Co reports 61.13% decrease in ownership of APLS / Apellis Pharmaceuticals, Inc.

On February 13, 2026 - Sei Investments Co filed a 13F-HR form disclosing ownership of 60,291 shares of Apellis Pharmaceuticals, Inc. (US:APLS) valued at $1,514,510 USD as of December 31, 2025. The entity filed a previous 13F-HR on November 13, 2025 disclosing 155,122 shares of Apellis Pharmaceuticals, Inc.. This represents a change in shares of -61.13% during the quarter. The current value of the position is $2,473,740 USD.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date
Effective
Date
Form Security Class ID Avg Price
Paid (Est)
Reported
Shares
ΔShares ΔShares
(%)
Reported
Value
(x1000)
ΔValue
(%)
Alloc
(%)
ΔAlloc ΔAlloc (%) Cost Basis
(x1000)
Unrealized
Gain/Loss
(x1000)
2026-02-13 2025-12-31 13F APELLIS PHARMACEUTICALS COM 03753U106 60,291 -94,831 -61.13 1,515 -56.87 0.0015
2025-11-13 2025-09-30 13F APELLIS PHARMACEUTICALS COM 03753U106 155,122 132,763 593.78 3,510 806.98 0.0038
2025-08-14 2025-06-30 13F APELLIS PHARMACEUTICALS COM 03753U106 22,359 22,359 387 0.0004
2025-02-11 2024-12-31 13F APELLIS PHARMACEUTICALS COM 03753U106 0 -30,155 -100.00 0 -100.00
2024-11-12 2024-09-30 13F APELLIS PHARMACEUTICALS COM 03753U106 30,155 -4,511 -13.01 870 -34.61 0.0011
2024-08-13 2024-06-30 13F APELLIS PHARMACEUTICALS COM 03753U106 34,666 -5,198 -13.04 1,330 -43.28 0.0019
2024-05-07 2024-03-31 13F APELLIS PHARMACEUTICALS COM 03753U106 39,864 14,531 57.36 2,343 54.45 0.0034
2024-02-14 2023-12-31 13F APELLIS PHARMACEUTICALS COM 03753U106 25,333 -7,340 -22.47 1,517 22.14 0.0024
2023-11-14 2023-09-30 13F APELLIS PHARMACEUTICALS COM 03753U106 32,673 -32,662 -49.99 1,242 -79.13 0.0022
2023-08-11 2023-06-30 13F APELLIS PHARMACEUTICALS COM 03753U106 65,335 14,140 27.62 5,952 76.30 0.0104
2023-05-12 2023-03-31 13F APELLIS PHARMACEUTICALS COM 03753U106 51,195 40,399 374.20 3,377 505.02 0.0063
2023-02-10 2022-12-31 13F APELLIS PHARMACEUTICALS COM 03753U106 10,796 -45,125 -80.69 558 -85.39 0.0012
2022-11-14 2022-09-30 13F APELLIS PHARMACEUTICALS COM 03753U106 55,921 55,921 3,820 0.0085
2021-11-12 2021-09-30 13F APELLIS PHARMACEUTICALS COM 03753U106 0 -19,674 -100.00 0 -100.00
2021-08-06 2021-06-30 13F APELLIS PHARMACEUTICALS COM 03753U106 19,674 3,406 20.94 1,243 33.51 0.0028
2021-05-12 2021-03-31 13F APELLIS PHARMACEUTICALS COM 03753U106 16,268 0 0.00 931 0.00 0.0023
2021-02-08 2020-12-31 13F APELLIS PHARMACEUTICALS COM 03753U106 16,268 16,268 931 0.0024
2020-08-17 2020-06-30 13F/A-1 APELLIS PHARMACEUTICALS COM 03753U106 0 -7,785 -100.00 0 -100.00
2020-05-14 2020-03-31 13F APELLIS PHARMACEUTICALS COM 03753U106 7,785 7,785 209 0.0008
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.