Biomea Fusion, Inc.
US ˙ NasdaqGS ˙ US09077A1060

SecurityBMEA / Biomea Fusion, Inc.
InstitutionXTX Topco Ltd
Latest Disclosed Ownership530,542 shares
Latest Disclosed Value $ 811,729
XTX Topco Ltd reports 103.22% increase in ownership of BMEA / Biomea Fusion, Inc.

On May 15, 2026 - XTX Topco Ltd filed a 13F-HR form disclosing ownership of 530,542 shares of Biomea Fusion, Inc. (US:BMEA) valued at $811,729 USD as of March 31, 2026. The entity filed a previous 13F-HR on February 17, 2026 disclosing 261,072 shares of Biomea Fusion, Inc.. This represents a change in shares of 103.22% during the quarter. The current value of the position is $689,705 USD.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date
Effective
Date
Form Security Class ID Avg Price
Paid (Est)
Reported
Shares
ΔShares ΔShares
(%)
Reported
Value
(x1000)
ΔValue
(%)
Alloc
(%)
ΔAlloc ΔAlloc (%) Cost Basis
(x1000)
Unrealized
Gain/Loss
(x1000)
2026-05-15 2026-03-31 13F BIOMEA FUSION COM 09077A106 530,542 269,470 103.22 812 151.08 0.0141
2026-02-17 2025-12-31 13F BIOMEA FUSION COM 09077A106 261,072 -4,231 -1.59 324 -39.63 0.0085
2025-11-14 2025-09-30 13F BIOMEA FUSION COM 09077A106 265,303 115,524 77.13 536 98.88 0.0278
2025-08-12 2025-06-30 13F BIOMEA FUSION COM 09077A106 149,779 149,779 270 0.0112
2025-05-08 2025-03-31 13F BIOMEA FUSION COM 09077A106 0 -64,047 -100.00 0 -100.00
2025-02-13 2024-12-31 13F BIOMEA FUSION COM 09077A106 64,047 64,047 249 0.0204
2024-11-14 2024-09-30 13F BIOMEA FUSION COM 09077A106 0 -45,929 -100.00 0 -100.00
2024-08-12 2024-06-30 13F BIOMEA FUSION COM 09077A106 45,929 45,929 207 0.0177
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.