Blueprint Medicines Corporation
US ˙ NasdaqGS ˙ US09627Y1091
DIESES SYMBOL IST NICHT MEHR AKTIV

SecurityBPMC / Blueprint Medicines Corporation
InstitutionRYDEX VARIABLE TRUST - Biotechnology Fund Variable Annuity
Latest Disclosed Ownership957 shares
Latest Disclosed Value $ 122,668
RYDEX VARIABLE TRUST - Biotechnology Fund Variable Annuity reports 18.41% decrease in ownership of BPMC / Blueprint Medicines Corporation

On August 27, 2025 - RYDEX VARIABLE TRUST - Biotechnology Fund Variable Annuity filed a NPORT-P form disclosing ownership of 957 shares of Blueprint Medicines Corporation (US:BPMC) valued at $122,668 USD as of June 30, 2025. The entity filed a previous NPORT-P on May 29, 2025 disclosing 1,173 shares of Blueprint Medicines Corporation. This represents a change in shares of -18.41% during the quarter. The current value of the position is $123,893 USD.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date
Effective
Date
Form Security Class ID Avg Price
Paid (Est)
Reported
Shares
ΔShares ΔShares
(%)
Reported
Value
(x1000)
ΔValue
(%)
Alloc
(%)
ΔAlloc ΔAlloc (%) Cost Basis
(x1000)
Unrealized
Gain/Loss
(x1000)
2025-08-27 2025-06-30 NP Blueprint Medicines EC US09627Y1091 957 -216 -18.41 123 18.45 1.3633
2025-05-29 2025-03-31 NP Blueprint Medicines EC US09627Y1091 1,173 77 7.03 104 8.42 1.1029
2025-03-03 2024-12-31 NP Blueprint Medicines EC US09627Y1091 1,096 -217 -16.53 96 -21.49 0.9583
2024-11-29 2024-09-30 NP Blueprint Medicines EC US09627Y1091 1,313 371 39.38 121 19.80 1.1001
2024-08-29 2024-06-30 NP Blueprint Medicines EC US09627Y1091 942 -421 -30.89 102 -21.71 0.9256
2024-05-30 2024-03-31 NP Blueprint Medicines EC US09627Y1091 1,363 -55 -3.88 129 -0.77 1.0965
2024-02-29 2023-12-31 NP Blueprint Medicines EC US09627Y1091 1,418 -427 -23.14 131 41.30 1.0720
2023-11-29 2023-09-30 NP Blueprint Medicines EC US09627Y1091 1,845 280 17.89 93 -6.12 0.8022
2023-08-28 2023-06-30 NP Blueprint Medicines EC US09627Y1091 1,565 -353 -18.40 99 13.95 0.7805
2023-05-30 2023-03-31 NP Blueprint Medicines EC US09627Y1091 1,918 -1,122 -36.91 86 -35.34 0.6536
2023-02-28 2022-12-31 NP Blueprint Medicines EC US09627Y1091 3,040 883 40.94 133 -6.34 0.8054
2022-11-29 2022-09-30 NP Blueprint Medicines EC US09627Y1091 2,157 -407 -15.87 142 10.08 0.9918
2022-08-29 2022-06-30 NP Blueprint Medicines EC US09627Y1091 2,564 -19 -0.74 130 -21.82 0.8885
2022-05-26 2022-03-31 NP Blueprint Medicines EC US09627Y1091 2,583 265 11.43 165 -33.47 0.9750
2022-02-28 2021-12-31 NP Blueprint Medicines EC US09627Y1091 2,318 106 4.79 248 9.25 1.0971
2021-11-29 2021-09-30 NP Blueprint Medicines EC US09627Y1091 2,212 -296 -11.80 227 3.18 0.9560
2021-08-27 2021-06-30 NP Blueprint Medicines EC US09627Y1091 2,508 134 5.64 221 -4.35 0.9239
2021-05-27 2021-03-31 NP Blueprint Medicines EC US09627Y1091 2,374 29 1.24 231 -12.21 1.0387
2021-03-01 2020-12-31 NP Blueprint Medicines EC US09627Y1091 2,345 -927 -28.33 263 37.17 1.0710
2020-06-01 2020-03-31 NP Blueprint Medicines EC US09627Y1091 3,272 -207 -5.95 191 -31.29 1.1712
2020-03-02 2019-12-31 NP Blueprint Medicines EC US09627Y1091 3,479 3,479 279 1.2900
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.