C4 Therapeutics, Inc.
US ˙ NasdaqGS ˙ US12529R1077

SecurityCCCC / C4 Therapeutics, Inc.
InstitutionFmr Llc
Latest Disclosed Ownership272,368 shares
Latest Disclosed Value $ 716,327
Fmr Llc reports 7.06% increase in ownership of CCCC / C4 Therapeutics, Inc.

On May 15, 2026 - Fmr Llc filed a 13F-HR form disclosing ownership of 272,368 shares of C4 Therapeutics, Inc. (US:CCCC) valued at $716,328 USD as of March 31, 2026. The entity filed a previous 13F-HR on February 17, 2026 disclosing 254,406 shares of C4 Therapeutics, Inc.. This represents a change in shares of 7.06% during the quarter. The current value of the position is $1,078,577 USD.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date
Effective
Date
Form Security Class ID Avg Price
Paid (Est)
Reported
Shares
ΔShares ΔShares
(%)
Reported
Value
(x1000)
ΔValue
(%)
Alloc
(%)
ΔAlloc ΔAlloc (%) Cost Basis
(x1000)
Unrealized
Gain/Loss
(x1000)
2026-05-15 2026-03-31 13F C4 THERAPEUTICS COM STK 12529R107 272,368 17,962 7.06 716 47.63 0.0000
2026-02-17 2025-12-31 13F C4 THERAPEUTICS COM STK 12529R107 254,406 43,058 20.37 486 3.41 0.0000
2025-11-13 2025-09-30 13F C4 THERAPEUTICS COM STK 12529R107 211,348 9,990 4.96 469 63.41 0.0000
2025-08-14 2025-06-30 13F C4 THERAPEUTICS COM STK 12529R107 201,358 7,608 3.93 288 -7.42 0.0000
2025-05-12 2025-03-31 13F C4 THERAPEUTICS COM STK 12529R107 193,750 -24,615 -11.27 310 -60.56 0.0000
2025-02-13 2024-12-31 13F C4 THERAPEUTICS COM STK 12529R107 218,365 32,424 17.44 786 -25.78 0.0000
2024-11-13 2024-09-30 13F C4 THERAPEUTICS COM STK 12529R107 185,941 162,314 686.99 1,060 871.56 0.0001
2024-08-13 2024-06-30 13F C4 THERAPEUTICS COM STK 12529R107 23,627 -13,661 -36.64 109 -64.14 0.0000
2024-05-13 2024-03-31 13F C4 THERAPEUTICS COM STK 12529R107 37,288 -272 -0.72 305 43.40 0.0000
2024-02-13 2023-12-31 13F C4 THERAPEUTICS COM STK 12529R107 37,560 -83,605 -69.00 212 -5.78 0.0000
2023-11-13 2023-09-30 13F C4 THERAPEUTICS COM STK 12529R107 121,165 66,398 121.24 225 50.00 0.0000
2023-08-11 2023-06-30 13F C4 THERAPEUTICS COM STK 12529R107 54,767 -335 -0.61 151 -13.29 0.0000
2023-08-11 2023-03-31 13F/A-1 C4 THERAPEUTICS COM STK 12529R107 55,102 2,763 5.28 173 -43.83 0.0000
2023-05-11 2023-03-31 13F C4 THERAPEUTICS COM STK 12529R107 55,102 2,763 173 0.0000
2023-02-13 2022-12-31 13F C4 THERAPEUTICS COM STK 12529R107 52,339 -5,181 -9.01 309 -38.89 0.0000
2022-11-10 2022-09-30 13F C4 THERAPEUTICS COM STK 12529R107 57,520 56,210 4,290.84 504 4,940.00 0.0001
2022-08-12 2022-06-30 13F C4 THERAPEUTICS COM STK 12529R107 1,310 -597,971 -99.78 10 -99.93 0.0000
2022-05-13 2022-03-31 13F C4 THERAPEUTICS COM STK 12529R107 599,281 -49,700 -7.66 14,539 -30.43 0.0012
2022-02-14 2021-12-31 13F C4 THERAPEUTICS COM STK 12529R107 648,981 0 0.00 20,897 -27.93 0.0015
2022-02-14 2021-09-30 13F/A-1 C4 THERAPEUTICS COM STK 12529R107 648,981 69,700 12.03 28,996 32.28 0.0023
2021-11-15 2021-09-30 13F C4 THERAPEUTICS COM STK 12529R107 648,981 69,700 28,996 0.0004
2021-08-13 2021-06-30 13F C4 THERAPEUTICS COM STK 12529R107 579,281 240,894 71.19 21,920 75.12 0.0017
2021-05-14 2021-03-31 13F C4 THERAPEUTICS COM STK 12529R107 338,387 -332,900 -49.59 12,517 -43.72 0.0011
2021-02-08 2020-12-31 13F C4 THERAPEUTICS COM STK 12529R107 671,287 671,287 22,240 0.0020
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.