Fmr Llc reports 10.45% increase in ownership of CDNA / CareDx, Inc.

CareDx, Inc.

US ˙ NasdaqGM ˙ US14167L1035

Security	CDNA / CareDx, Inc.
Institution	Fmr Llc
Latest Disclosed Ownership	231,305 shares
Latest Disclosed Value	$ 4,015,458

On May 15, 2026 - Fmr Llc filed a 13F-HR form disclosing ownership of 231,305 shares of CareDx, Inc. (US:CDNA) valued at $4,015,455 USD as of March 31, 2026. The entity filed a previous 13F-HR on February 17, 2026 disclosing 209,419 shares of CareDx, Inc.. This represents a change in shares of 10.45% during the quarter. The current value of the position is $5,160,415 USD.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Disclosed Equity Positions (from 13F/NPORT Filings)

File Date	Effective Date	Form	Security	Class	ID	Reported Shares	ΔShares	ΔShares (%)	Reported Value (x1000)	ΔValue (%)	Alloc (%)
2026-05-15	2026-03-31	13F	CAREDX	COM	14167L103	231,305	21,886	10.45	4,015	1.77	0.0000
2026-02-17	2025-12-31	13F	CAREDX	COM	14167L103	209,419	53,803	34.57	3,945	74.40	0.0002
2025-11-13	2025-09-30	13F	CAREDX	COM	14167L103	155,616	151,405	3,595.46	2,263	2,658.54	0.0001
2025-08-14	2025-06-30	13F	CAREDX	COM	14167L103	4,211	-88,093	-95.44	82	-94.99	0.0000
2025-05-12	2025-03-31	13F	CAREDX	COM	14167L103	92,304	10,450	12.77	1,638	-6.51	0.0001
2025-02-13	2024-12-31	13F	CAREDX	COM	14167L103	81,854	-543,696	-86.91	1,753	-91.03	0.0001
2024-11-13	2024-09-30	13F	CAREDX	COM	14167L103	625,550	556,230	802.41	19,533	1,715.24	0.0012
2024-08-13	2024-06-30	13F	CAREDX	COM	14167L103	69,320	4,815	7.46	1,077	57.54	0.0001
2024-05-13	2024-03-31	13F	CAREDX	COM	14167L103	64,505	-141	-0.22	683	-11.87	0.0000
2024-02-13	2023-12-31	13F	CAREDX	COM	14167L103	64,646	-5,752	-8.17	776	57.52	0.0001
2023-11-13	2023-09-30	13F	CAREDX	COM	14167L103	70,398	3,173	4.72	493	-13.84	0.0000
2023-08-11	2023-06-30	13F	CAREDX	COM	14167L103	67,225	25,769	62.16	571	51.06	0.0000
2023-08-11	2023-03-31	13F/A-1	CAREDX	COM	14167L103	41,456	-793	-1.88	379	-21.58	0.0000
2023-05-11	2023-03-31	13F	CAREDX	COM	14167L103	41,456	-793		379		0.0000
2023-02-13	2022-12-31	13F	CAREDX	COM	14167L103	42,249	15,382	57.25	482	5.47	0.0000
2022-11-10	2022-09-30	13F	CAREDX	COM	14167L103	26,867	20,915	351.39	457	257.03	0.0000
2022-08-12	2022-06-30	13F	CAREDX	COM	14167L103	5,952	-22,439	-79.04	128	-87.82	0.0000
2022-05-13	2022-03-31	13F	CAREDX	COM	14167L103	28,391	-47,610	-62.64	1,051	-69.59	0.0001
2022-02-14	2021-12-31	13F	CAREDX	COM	14167L103	76,001	-103,172	-57.58	3,456	-69.56	0.0003
2022-02-14	2021-09-30	13F/A-1	CAREDX	COM	14167L103	179,173	-186	-0.10	11,355	-30.83	0.0009
2021-11-15	2021-09-30	13F	CAREDX	COM	14167L103	179,173	-186		11,355		0.0002
2021-08-13	2021-06-30	13F	CAREDX	COM	14167L103	179,359	-147,608	-45.14	16,415	-26.27	0.0013
2021-05-14	2021-03-31	13F	CAREDX	COM	14167L103	326,967	3,242	1.00	22,263	-5.08	0.0019
2021-02-08	2020-12-31	13F	CAREDX	COM	14167L103	323,725	2,735	0.85	23,454	92.59	0.0021
2020-11-13	2020-09-30	13F	CAREDX	COM	14167L103	320,990	-287,583	-47.26	12,178	-43.52	0.0012
2020-08-24	2020-06-30	13F/A-1	CAREDX	COM	14167L103	608,573	607,987	103,752.05	21,563	165,769.23	0.0024
2020-08-13	2020-06-30	13F	CAREDX	COM	14167L103	608,573	607,987		21,563		529.7398
2020-05-14	2020-03-31	13F	CAREDX	COM	14167L103	586	-308	-34.45	13	-31.58	0.0000
2020-02-07	2019-12-31	13F	CAREDX	COM	14167L103	894	-4,992	-84.81	19	-85.82	0.0000
2019-11-13	2019-09-30	13F	CAREDX	COM	14167L103	5,886	-1,712,877	-99.66	134	-99.78	0.0000
2019-08-13	2019-06-30	13F	CAREDX	COM	14167L103	1,718,763	1,718,763		61,858		0.0072
2019-02-13	2018-12-31	13F	CAREDX	COM	14167L103	0	-20,000	-100.00	0	-100.00
2018-11-09	2018-09-30	13F	CAREDX	COM	14167L103	20,000	20,000		577		0.0001

Legend

Shares: The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value: The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price: The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class: This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred

Allocation (%): The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation: The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%): The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis: The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss: This is the market value of the position as of the effective date minus the cost basis.