Centene Corporation
US ˙ NYSE ˙ US15135B1017

SecurityCNC / Centene Corporation
InstitutionD. E. Shaw & Co., Inc.
ManagerDE Shaw
Latest Disclosed Ownership7,528,177 shares
Latest Disclosed Value $ 246,472,515
D. E. Shaw & Co., Inc. ownership in CNC / Centene Corporation

On May 15, 2026 - D. E. Shaw & Co., Inc. filed a 13F-HR form disclosing ownership of 7,528,177 shares of Centene Corporation (US:CNC) valued at $246,472,515 USD as of March 31, 2026. The entity filed a previous 13F-HR on February 17, 2026 disclosing 8,347,666 shares of Centene Corporation. This represents a change in shares of -9.82% during the quarter. The current value of the position is $448,302,940 USD.

D. E. Shaw & Co., Inc. has a history of taking positions in derivatives of the underlying security (CNC) in the form of stock options. The firm currently holds call options representing 55,400 of underlying shares valued at $1,813,796 USD and put options representing 1,539,200 of underlying shares valued at $50,393,408 USD .

Note: prior versions of this page mistakenly stated that the share values represented the number of options, not the number of underlying shares. For more information on the data backing these reports, please see the SEC document Frequently Asked Questions About Form 13F.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Institutional Put/Call Ratios
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In addition to reporting standard equity and debt issues, institutions with more than 100MM assets under management must also disclose their put and call option holdings. Since put options generally indicate negative sentiment, and call options indicate positive sentiment, we can get a sense of the overall institutional sentiment by plotting the ratio of puts to calls. The chart to the right plots the historical put/call ratio for this instrument.

Using Put/Call Ratio as an indicator of investor sentiment overcomes one of the key deficiencies of using total institutional ownership, which is that a significant amount of assets under management are invested passively to track indices. Passively-managed funds do not typically buy options, so the put/call ratio indicator more closely tracks the sentiment of actively-managed funds.

CNC / Centene Corporation Historical Put/Call Ratio
Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date
Effective
Date
Form Security Class ID Avg Price
Paid (Est)
Reported
Shares
ΔShares ΔShares
(%)
Reported
Value
(x1000)
ΔValue
(%)
Alloc
(%)
ΔAlloc ΔAlloc (%) Cost Basis
(x1000)
Unrealized
Gain/Loss
(x1000)
2026-05-15 2026-03-31 13F CENTENE CORP DEL COM 15135B101 7,528,177 -819,489 -9.82 246,473 -28.25 0.1088
2026-02-17 2025-12-31 13F CENTENE CORP DEL COM 15135B101 8,347,666 -2,281,363 -21.46 343,506 -9.42 0.1883
2025-11-14 2025-09-30 13F CENTENE CORP DEL COM 15135B101 10,629,029 7,757,543 270.16 379,244 143.32 0.2141
2025-08-14 2025-06-30 13F CENTENE CORP DEL COM 15135B101 2,871,486 195,256 7.30 155,864 -4.07 0.1105
2025-05-15 2025-03-31 13F CENTENE CORP DEL COM 15135B101 2,676,230 105,156 4.09 162,474 4.31 0.1446
2025-02-14 2024-12-31 13F CENTENE CORP DEL COM 15135B101 2,571,074 2,308,912 880.72 155,756 689.23 0.1143
2024-11-14 2024-09-30 13F CENTENE CORP DEL COM 15135B101 262,162 -66,387 -20.21 19,736 -9.40 0.0169
2024-08-14 2024-06-30 13F CENTENE CORP DEL COM 15135B101 328,549 41,671 14.53 21,783 -3.25 0.0204
2024-05-15 2024-03-31 13F CENTENE CORP DEL COM 15135B101 286,878 -169,891 -37.19 22,514 -33.58 0.0193
2024-02-14 2023-12-31 13F CENTENE CORP DEL COM 15135B101 456,769 -683,198 -59.93 33,897 -56.83 0.0296
2023-11-14 2023-09-30 13F CENTENE CORP DEL COM 15135B101 1,139,967 -403,795 -26.16 78,521 -24.59 0.0820
2023-08-14 2023-06-30 13F CENTENE CORP DEL COM 15135B101 1,543,762 228,781 17.40 104,127 25.27 0.1064
2023-05-15 2023-03-31 13F CENTENE CORP DEL COM 15135B101 1,314,981 1,083,452 467.96 83,120 337.77 0.0890
2023-02-14 2022-12-31 13F CENTENE CORP DEL COM 15135B101 231,529 -378,281 -62.03 18,988 -59.98 0.0210
2022-11-14 2022-09-30 13F CENTENE CORP DEL COM 15135B101 609,810 347,590 132.56 47,449 113.86 0.0567
2022-08-15 2022-06-30 13F CENTENE CORP DEL COM 15135B101 262,220 172,575 192.51 22,187 193.98 0.0260
2022-05-16 2022-03-31 13F CENTENE CORP DEL COM 15135B101 89,645 -24,009 -21.12 7,547 -19.41 0.0071
2022-02-14 2021-12-31 13F CENTENE CORP DEL COM 15135B101 113,654 96,652 568.47 9,365 784.32 0.0078
2021-11-15 2021-09-30 13F CENTENE CORP DEL COM 15135B101 17,002 -46,314 -73.15 1,059 -77.06 0.0010
2021-08-16 2021-06-30 13F CENTENE CORP DEL COM 15135B101 63,316 -1,294,105 -95.34 4,617 -94.68 0.0040
2021-05-17 2021-03-31 13F CENTENE CORP DEL COM 15135B101 1,357,421 1,308,024 2,647.98 86,753 2,824.92 0.0837
2021-02-16 2020-12-31 13F CENTENE CORP DEL COM 15135B101 49,397 4,702 10.52 2,966 13.77 0.0027
2020-11-16 2020-09-30 13F CENTENE CORP DEL COM 15135B101 44,695 -570,851 -92.74 2,607 -93.34 0.0027
2020-08-14 2020-06-30 13F CENTENE CORP DEL COM 15135B101 615,546 602,332 4,558.29 39,118 4,883.18 0.0466
2020-05-15 2020-03-31 13F CENTENE CORP DEL COM 15135B101 13,214 8,848 202.66 785 186.50 0.0012
2020-02-14 2019-12-31 13F CENTENE CORP DEL COM 15135B101 4,366 -379,312 -98.86 274 -98.35 0.0003
2019-11-14 2019-09-30 13F CENTENE CORP DEL COM 15135B101 383,678 -1,222,406 -76.11 16,598 -80.29 0.0204
2019-08-14 2019-06-30 13F CENTENE CORP DEL COM 15135B101 1,606,084 -990,272 -38.14 84,223 -38.91 0.1050
2019-05-15 2019-03-31 13F CENTENE CORP DEL COM 15135B101 2,596,356 2,378,420 1,091.34 137,866 448.65 0.1781
2019-02-14 2018-12-31 13F CENTENE CORP DEL COM 15135B101 217,936 121,146 125.16 25,128 79.31 0.0346
2018-11-14 2018-09-30 13F CENTENE CORP DEL COM 15135B101 96,790 77,120 392.07 14,014 478.14 0.0168
2018-08-14 2018-06-30 13F CENTENE CORP DEL COM 15135B101 19,670 -192,870 -90.75 2,424 -89.33 0.0032
2018-05-15 2018-03-31 13F CENTENE CORP DEL COM 15135B101 212,540 -42,932 -16.80 22,714 -11.87 0.0309
2018-02-14 2017-12-31 13F CENTENE CORP DEL COM 15135B101 255,472 90,088 54.47 25,772 61.03 0.0355
2017-11-14 2017-09-30 13F CENTENE CORP DEL COM 15135B101 165,384 -32,106 -16.26 16,004 1.45 0.0246
2017-08-14 2017-06-30 13F CENTENE CORP DEL COM 15135B101 197,490 117,515 146.94 15,776 176.82 0.0261
2017-05-15 2017-03-31 13F CENTENE CORP DEL COM 15135B101 79,975 67,742 553.76 5,699 724.75 0.0100
2017-02-14 2016-12-31 13F CENTENE CORP DEL COM 15135B101 12,233 12,233 0.00 691 0.0012
2016-08-15 2016-06-30 13F CENTENE CORP DEL COM 15135B101 0 -568,478 -100.00 0 -100.00
2016-05-16 2016-03-31 13F CENTENE CORP DEL COM 15135B101 568,478 568,478 0.00 35,001 0.0628
2015-11-16 2015-09-30 13F CENTENE CORP DEL COM 15135B101 0 -15,736 -100.00 0 -100.00
2015-08-14 2015-06-30 13F CENTENE CORP DEL COM 15135B101 15,736 15,736 0.00 1,266 0.0019
2015-05-15 2015-03-31 13F CENTENE CORP DEL COM 15135B101 0 -3,579 -100.00 0 -100.00
2015-02-17 2014-12-31 13F CENTENE CORP DEL COM 15135B101 3,579 -82,518 -95.84 372 -93.06 0.0005
2014-05-15 2014-03-31 13F CENTENE CORP DEL COM 15135B101 86,097 -176,929 -67.27 5,360 -65.43 0.0076
2014-02-14 2013-12-31 13F CENTENE CORP DEL COM 15135B101 263,026 97,394 58.80 15,505 46.36 0.0211
2013-11-20 2013-09-30 13F/A-1 CENTENE CORP DEL COM 15135B101 165,632 86,468 109.23 10,594 155.09 0.0169
2013-11-14 2013-09-30 13F CENTENE CORP DEL COM 15135B101 165,632 10,594
2013-08-14 2013-06-30 13F CENTENE CORP DEL COM 15135B101 79,164 79,164 4,153 0.0078
Disclosed Call Options
File
Date
Effective
Date
Form Security Class ID Opt Avg Share
Price
Shares ΔShares
(%)
Value
(x1000)
ΔValue
(%)
Prior Allocation
(%)
Allocation
(%)
ΔAllocation
(%)
Cost Basis
(x1000)
Profit
(x1000)
Return
(%)
2026-05-15 2026-03-31 13F CENTENE CORP DEL COM Call 55,400 -51.95 1,814 -61.78 n/a n/a n/a
2026-02-17 2025-12-31 13F CENTENE CORP DEL COM Call 115,300 399.13 4,745 475.73 n/a n/a n/a
2025-11-14 2025-09-30 13F CENTENE CORP DEL COM Call 23,100 824 n/a n/a n/a
2022-05-16 2022-03-31 13F CENTENE CORP DEL COM Call 0 -100.00 0 -100.00 n/a n/a n/a
2022-02-14 2021-12-31 13F CENTENE CORP DEL COM Call 20,000 0.00 1,648 32.26 n/a n/a n/a
2021-11-15 2021-09-30 13F CENTENE CORP DEL COM Call 20,000 -66.67 1,246 -71.53 n/a n/a n/a
2021-08-16 2021-06-30 13F CENTENE CORP DEL COM Call 60,000 200.00 4,376 242.41 n/a n/a n/a
2021-05-17 2021-03-31 13F CENTENE CORP DEL COM Call 20,000 1,278 n/a n/a n/a
2021-02-16 2020-12-31 13F CENTENE CORP DEL COM Call 0 -100.00 0 -100.00 n/a n/a n/a
2020-11-16 2020-09-30 13F CENTENE CORP DEL COM Call 41,400 -49.01 2,415 -53.20 n/a n/a n/a
2020-08-14 2020-06-30 13F CENTENE CORP DEL COM Call 81,200 58.59 5,160 69.63 n/a n/a n/a
2020-05-15 2020-03-31 13F CENTENE CORP DEL COM Call 51,200 -40.81 3,042 -44.06 n/a n/a n/a
2020-02-14 2019-12-31 13F CENTENE CORP DEL COM Call 86,500 0.00 5,438 45.32 n/a n/a n/a
2019-11-14 2019-09-30 13F CENTENE CORP DEL COM Call 86,500 -63.16 3,742 -69.61 n/a n/a n/a
2019-08-14 2019-06-30 13F CENTENE CORP DEL COM Call 234,800 12,313 n/a n/a n/a
2019-05-15 2019-03-31 13F CENTENE CORP DEL COM Call 0 -100.00 0 -100.00 n/a n/a n/a
2019-02-14 2018-12-31 13F CENTENE CORP DEL COM Call 19,300 -8.10 2,225 -26.81 n/a n/a n/a
2018-11-14 2018-09-30 13F CENTENE CORP DEL COM Call 21,000 -45.03 3,040 -35.42 n/a n/a n/a
2018-08-14 2018-06-30 13F CENTENE CORP DEL COM Call 38,200 4,707 n/a n/a n/a
2016-05-16 2016-03-31 13F CENTENE CORP DEL COM Call 0 0 n/a n/a n/a
2016-02-16 2015-12-31 13F CENTENE CORP DEL COM Call 0 -100.00 0 -100.00 n/a n/a n/a
2015-11-16 2015-09-30 13F CENTENE CORP DEL COM Call 27,800 0.00 1,508 -32.53 n/a n/a n/a
2015-08-14 2015-06-30 13F CENTENE CORP DEL COM Call 27,800 39.00 2,235 58.06 n/a n/a n/a
2015-05-15 2015-03-31 13F CENTENE CORP DEL COM Call 20,000 13.64 1,414 -22.65 n/a n/a n/a
2015-02-17 2014-12-31 13F CENTENE CORP DEL COM Call 17,600 0.00 1,828 25.55 n/a n/a n/a
2014-11-14 2014-09-30 13F CENTENE CORP DEL COM Call 17,600 0.00 1,456 9.39 n/a n/a n/a
2014-08-14 2014-06-30 13F CENTENE CORP DEL COM Call 17,600 1,331 n/a n/a n/a
Disclosed Put Options
File
Date
Effective
Date
Form Security Class ID Opt Avg Share Price Shares ΔShares
(%)
Value
(x1000)
ΔValue
(%)
Prior Allocation
(%)
Allocation
(%)
ΔAllocation
(%)
Cost Basis
(x1000)
Profit
(x1000)
Return
(%)
2026-05-15 2026-03-31 13F CENTENE CORP DEL COM Put 1,539,200 -0.06 50,393 -20.48 n/a n/a n/a
2026-02-17 2025-12-31 13F CENTENE CORP DEL COM Put 1,540,100 30.45 63,375 50.45 n/a n/a n/a
2025-11-14 2025-09-30 13F CENTENE CORP DEL COM Put 1,180,600 3,835.33 42,124 2,487.41 n/a n/a n/a
2025-08-14 2025-06-30 13F CENTENE CORP DEL COM Put 30,000 -24.43 1,628 -32.45 n/a n/a n/a
2025-05-15 2025-03-31 13F CENTENE CORP DEL COM Put 39,700 -47.42 2,410 -47.30 n/a n/a n/a
2025-02-14 2024-12-31 13F CENTENE CORP DEL COM Put 75,500 4,574 n/a n/a n/a
2021-02-16 2020-12-31 13F CENTENE CORP DEL COM Put 0 -100.00 0 -100.00 n/a n/a n/a
2020-11-16 2020-09-30 13F CENTENE CORP DEL COM Put 14,500 -79.86 846 -81.51 n/a n/a n/a
2020-08-14 2020-06-30 13F CENTENE CORP DEL COM Put 72,000 1,369.39 4,576 1,472.51 n/a n/a n/a
2020-05-15 2020-03-31 13F CENTENE CORP DEL COM Put 4,900 -99.15 291 -99.20 n/a n/a n/a
2020-02-14 2019-12-31 13F CENTENE CORP DEL COM Put 579,200 -28.42 36,414 4.02 n/a n/a n/a
2019-11-14 2019-09-30 13F CENTENE CORP DEL COM Put 809,200 41.47 35,006 16.70 n/a n/a n/a
2019-08-14 2019-06-30 13F CENTENE CORP DEL COM Put 572,000 29,996 n/a n/a n/a
2016-05-16 2016-03-31 13F CENTENE CORP DEL COM Put 0 0 n/a n/a n/a
2016-02-16 2015-12-31 13F CENTENE CORP DEL COM Put 0 -100.00 0 -100.00 n/a n/a n/a
2015-11-16 2015-09-30 13F CENTENE CORP DEL COM Put 5,800 -90.94 315 -93.88 n/a n/a n/a
2015-08-14 2015-06-30 13F CENTENE CORP DEL COM Put 64,000 60.00 5,146 81.97 n/a n/a n/a
2015-05-15 2015-03-31 13F CENTENE CORP DEL COM Put 40,000 68.78 2,828 14.91 n/a n/a n/a
2015-02-17 2014-12-31 13F CENTENE CORP DEL COM Put 23,700 0.00 2,461 25.56 n/a n/a n/a
2014-11-14 2014-09-30 13F CENTENE CORP DEL COM Put 23,700 0.00 1,960 9.38 n/a n/a n/a
2014-08-14 2014-06-30 13F CENTENE CORP DEL COM Put 23,700 0.00 1,792 21.49 n/a n/a n/a
2014-05-15 2014-03-31 13F CENTENE CORP DEL COM Put 23,700 0.00 1,475 5.58 n/a n/a n/a
2014-02-14 2013-12-31 13F CENTENE CORP DEL COM Put 23,700 1,397 n/a n/a n/a
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.