Crinetics Pharmaceuticals, Inc.
US ˙ NasdaqGS ˙ US22663K1079

SecurityCRNX / Crinetics Pharmaceuticals, Inc.
InstitutionDriehaus Capital Management Llc
Latest Disclosed Ownership6,395,922 shares
Ownership 6.11%
Driehaus Capital Management Llc ownership in CRNX / Crinetics Pharmaceuticals, Inc.

2026-05-15 - Driehaus Capital Management Llc has filed an SCHEDULE 13G/A form with the Securities and Exchange Commission (SEC) disclosing ownership of 6,395,922 shares of Crinetics Pharmaceuticals, Inc. (US:CRNX). This represents 6.11 percent ownership of the company. In their previous filing dated 2024-02-14 , Driehaus Capital Management Llc had reported owning 5,039,477 shares, indicating an increase of 26.92 percent.

Institutional Ownership: 13D/G Filings

This table shows a history of the 13D/G filings made by the investor and/or investor group. Note that the share values in this table are not directly comparable to any numbers shown in the 13F table (if any).

File
Date
Effective
Date
Form Prev
Shares
Latest
Shares
ΔShares
(Percent)
Ownership
(Percent)
ΔOwnership
(Percent)
2026-05-15 2026-05-15 13G/A 5,039,477 6,395,922 26.92 6.11 -18.97
2024-02-14 2024-02-14 13G/A 5,624,744 5,039,477 -10.41 7.54 -27.85
2023-02-08 2023-02-08 13G/A 4,793,638 5,624,744 17.34 10.45 3.57
2022-01-10 2022-01-10 13G 4,793,638 10.09

Important Note: One of the primary uses of the 13D/G filings is to evaluate the ability of a firm to control a company (ie, the "beneficial ownership"). To that end, firms are required to report not just direct holdings in companies, but indirect holdings that they control. For investment firms, these indirect holdings can include shares in funds they manage, advisory accounts, and in the case of activist campaigns, pledged votes. Therefore, share counts listed in 13D/G filings can differ significantly than share counts listed in 13F filings.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date
Effective
Date
Form Security Class ID Avg Price
Paid (Est)
Reported
Shares
ΔShares ΔShares
(%)
Reported
Value
(x1000)
ΔValue
(%)
Alloc
(%)
ΔAlloc ΔAlloc (%) Cost Basis
(x1000)
Unrealized
Gain/Loss
(x1000)
2026-05-15 2026-03-31 13F Crinetics Pharmaceuticals COM 22663K107 6,395,922 8,182 0.13 232,300 -21.88 1.7076
2026-02-17 2025-12-31 13F Crinetics Pharmaceuticals COM 22663K107 6,387,740 -93,873 -1.45 297,349 10.15 2.0198
2025-11-14 2025-09-30 13F CRINETICS PHARMACEUTICALS IN COM 22663K107 6,481,613 81,588 1.27 269,959 46.67 1.9336
2025-08-14 2025-06-30 13F CRINETICS PHARMACEUTICALS IN COM 22663K107 6,400,025 160,123 2.57 184,065 -12.05 1.4727
2025-05-15 2025-03-31 13F CRINETICS PHARMACEUTICALS IN COM 22663K107 6,239,902 98,888 1.61 209,286 -33.35 2.0174
2025-02-14 2024-12-31 13F CRINETICS PHARMACEUTICALS IN COM 22663K107 6,141,014 255,766 4.35 313,990 4.41 2.5913
2024-11-14 2024-09-30 13F CRINETICS PHARMACEUTICALS IN COM 22663K107 5,885,248 -226,925 -3.71 300,736 9.85 2.5818
2024-08-15 2024-06-30 13F/A-1 CRINETICS PHARMACEUTICALS IN COM 22663K107 6,112,173 885,876 16.95 273,764 11.90 2.6484
2024-08-14 2024-06-30 13F CRINETICS PHARMACEUTICALS IN COM 22663K107 6,112,173 885,876 273,764 2.6395
2024-05-15 2024-03-31 13F CRINETICS PHARMACEUTICALS IN COM 22663K107 5,226,297 186,340 3.70 244,643 36.43 2.4372
2024-02-14 2023-12-31 13F CRINETICS PHARMACEUTICALS IN COM 22663K107 5,039,957 -92,330 -1.80 179,322 17.48 2.1603
2023-11-14 2023-09-30 13F CRINETICS PHARMACEUTICALS IN COM 22663K107 5,132,287 -165,801 -3.13 152,634 59.87 1.9842
2023-08-14 2023-06-30 13F CRINETICS PHARMACEUTICALS IN COM 22663K107 5,298,088 8,569 0.16 95,472 12.39 1.2054
2023-05-15 2023-03-31 13F CRINETICS PHARMACEUTICALS IN COM 22663K107 5,289,519 -335,225 -5.96 84,950 -17.47 1.1923
2023-02-14 2022-12-31 13F CRINETICS PHARMACEUTICALS IN COM 22663K107 5,624,744 -7,214 -0.13 102,933 -6.94 1.5346
2022-11-14 2022-09-30 13F CRINETICS PHARMACEUTICALS IN COM 22663K107 5,631,958 157,499 2.88 110,612 8.34 1.6749
2022-08-15 2022-06-30 13F CRINETICS PHARMACEUTICALS IN COM 22663K107 5,474,459 530,446 10.73 102,099 -5.92 1.6538
2022-05-16 2022-03-31 13F CRINETICS PHARMACEUTICALS IN COM 22663K107 4,944,013 150,375 3.14 108,521 -20.31 1.3325
2022-02-14 2021-12-31 13F CRINETICS PHARMACEUTICALS IN COM 22663K107 4,793,638 1,795,126 59.87 136,187 115.76 1.3898
2021-11-15 2021-09-30 13F CRINETICS PHARMACEUTICALS IN COM 22663K107 2,998,512 290,687 10.74 63,119 23.66 0.7484
2021-08-16 2021-06-30 13F CRINETICS PHARMACEUTICALS IN COM 22663K107 2,707,825 704,137 35.14 51,043 66.72 0.6764
2021-05-17 2021-03-31 13F CRINETICS PHARMACEUTICALS IN COM 22663K107 2,003,688 549,722 37.81 30,616 49.24 0.4517
2021-02-16 2020-12-31 13F CRINETICS PHARMACEUTICALS IN COM 22663K107 1,453,966 579,124 66.20 20,515 49.65 0.3315
2020-11-16 2020-09-30 13F CRINETICS PHARMACEUTICALS IN COM 22663K107 874,842 -11,920 -1.34 13,709 -11.76 0.2814
2020-08-14 2020-06-30 13F CRINETICS PHARMACEUTICALS IN COM 22663K107 886,762 886,762 15,536 0.3779
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.