CytomX Therapeutics, Inc.
US ˙ NasdaqGS ˙ US23284F1057

SecurityCTMX / CytomX Therapeutics, Inc.
InstitutionNorthern Trust Corp
Latest Disclosed Ownership612,141 shares
Latest Disclosed Value $ 2,877,063
Northern Trust Corp reports 47.44% increase in ownership of CTMX / CytomX Therapeutics, Inc.

On May 14, 2026 - Northern Trust Corp filed a 13F-HR form disclosing ownership of 612,141 shares of CytomX Therapeutics, Inc. (US:CTMX) valued at $2,877,063 USD as of March 31, 2026. The entity filed a previous 13F-HR on February 17, 2026 disclosing 415,178 shares of CytomX Therapeutics, Inc.. This represents a change in shares of 47.44% during the quarter. The current value of the position is $1,946,608 USD.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date		 Effective
Date		Form Security Class ID Avg Price
Paid (Est)		 Reported
Shares		 ΔShares ΔShares
(%)		 Reported
Value
(x1000)		 ΔValue
(%)		 Alloc
(%)		 ΔAlloc ΔAlloc (%) Cost Basis
(x1000)		 Unrealized
Gain/Loss
(x1000)
2026-05-14 2026-03-31 13F CYTOMX THERAPEUTICS COM 23284F105 612,141 196,963 47.44 2,877 62.73 0.0001
2026-02-17 2025-12-31 13F CYTOMX THERAPEUTICS COM 23284F105 415,178 25,493 6.54 1,769 42.24 0.0002
2025-11-14 2025-09-30 13F CYTOMX THERAPEUTICS COM 23284F105 389,685 -60,422 -13.42 1,243 21.74 0.0002
2025-08-13 2025-06-30 13F CYTOMX THERAPEUTICS COM 23284F105 450,107 299,475 198.81 1,022 974.74 0.0001
2025-05-13 2025-03-31 13F CYTOMX THERAPEUTICS COM 23284F105 150,632 0 0.00 96 -38.71 0.0000
2025-02-14 2024-12-31 13F CYTOMX THERAPEUTICS COM 23284F105 150,632 20,746 15.97 155 1.31 0.0000
2024-11-13 2024-09-30 13F CYTOMX THERAPEUTICS COM 23284F105 129,886 -1,141 -0.87 153 -3.77 0.0000
2024-08-14 2024-06-30 13F CYTOMX THERAPEUTICS COM 23284F105 131,027 -3,091 -2.30 160 -45.55 0.0000
2024-05-14 2024-03-31 13F CYTOMX THERAPEUTICS COM 23284F105 134,118 -1,184 -0.88 292 39.71 0.0001
2024-02-13 2023-12-31 13F CYTOMX THERAPEUTICS COM 23284F105 135,302 15,383 12.83 210 35.71 0.0000
2023-11-13 2023-09-30 13F CYTOMX THERAPEUTICS COM 23284F105 119,919 305 0.25 155 -24.88 0.0000
2023-08-11 2023-06-30 13F CYTOMX THERAPEUTICS COM 23284F105 119,614 -386 -0.32 206 13.26 0.0000
2023-05-15 2023-03-31 13F CYTOMX THERAPEUTICS COM 23284F105 120,000 7,570 6.73 181 1.12 0.0000
2023-02-13 2022-12-31 13F CYTOMX THERAPEUTICS COM 23284F105 112,430 0 0.00 180 9.82 0.0000
2022-11-14 2022-09-30 13F CYTOMX THERAPEUTICS COM 23284F105 112,430 -52 -0.05 163 -20.87 0.0000
2022-08-12 2022-06-30 13F CYTOMX THERAPEUTICS COM 23284F105 112,482 -460,953 -80.38 206 -86.54 0.0000
2022-05-13 2022-03-31 13F CYTOMX THERAPEUTICS COM 23284F105 573,435 -41,886 -6.81 1,531 -42.53 0.0003
2022-02-08 2021-12-31 13F CYTOMX THERAPEUTICS COM 23284F105 615,321 -39,365 -6.01 2,664 -20.07 0.0004
2021-11-15 2021-09-30 13F CYTOMX THERAPEUTICS COM 23284F105 654,686 -11,788 -1.77 3,333 -21.02 0.0006
2021-08-13 2021-06-30 13F CYTOMX THERAPEUTICS COM 23284F105 666,474 -18,451 -2.69 4,220 -20.30 0.0007
2021-05-12 2021-03-31 13F CYTOMX THERAPEUTICS COM 23284F105 684,925 160,374 30.57 5,295 54.15 0.0010
2021-02-11 2020-12-31 13F CYTOMX THERAPEUTICS COM 23284F105 524,551 -5,833 -1.10 3,435 -2.61 0.0007
2020-11-16 2020-09-30 13F CYTOMX THERAPEUTICS COM 23284F105 530,384 -38,686 -6.80 3,527 -25.61 0.0008
2020-08-14 2020-06-30 13F CYTOMX THERAPEUTICS COM 23284F105 569,070 -6,350 -1.10 4,741 7.43 0.0011
2020-05-14 2020-03-31 13F CYTOMX THERAPEUTICS COM 23284F105 575,420 14,970 2.67 4,413 -5.22 0.0013
2020-02-14 2019-12-31 13F CYTOMX THERAPEUTICS COM 23284F105 560,450 1,730 0.31 4,656 12.93 0.0010
2019-11-13 2019-09-30 13F CYTOMX THERAPEUTICS COM 23284F105 558,720 12,642 2.32 4,123 -32.71 0.0010
2019-08-13 2019-06-30 13F CYTOMX THERAPEUTICS COM 23284F105 546,078 4,058 0.75 6,127 5.15 0.0015
2019-05-13 2019-03-31 13F CYTOMX THERAPEUTICS COM 23284F105 542,020 2,031 0.38 5,827 -28.54 0.0014
2019-02-12 2018-12-31 13F CYTOMX THERAPEUTICS COM 23284F105 539,989 -423 -0.08 8,154 -18.44 0.0023
2018-11-14 2018-09-30 13F CYTOMX THERAPEUTICS COM 23284F105 540,412 101,278 23.06 9,998 -0.41 0.0024
2018-09-18 2018-06-30 13F/A-1 CYTOMX THERAPEUTICS COM 23284F105 439,134 116,119 35.95 10,039 9.24 0.0025
2018-08-14 2018-06-30 13F CYTOMX THERAPEUTICS COM 23284F105 441,435 118,420 10,091
2018-05-09 2018-03-31 13F CYTOMX THERAPEUTICS COM 23284F105 323,015 -167 -0.05 9,190 34.71 0.0024
2018-02-14 2017-12-31 13F CYTOMX THERAPEUTICS COM 23284F105 323,182 -6,329 -1.92 6,822 13.95 0.0017
2017-11-13 2017-09-30 13F CYTOMX THERAPEUTICS COM 23284F105 329,511 12,925 4.08 5,987 22.01 0.0016
2017-08-11 2017-06-30 13F CYTOMX THERAPEUTICS COM 23284F105 316,586 84,602 36.47 4,907 22.49 0.0014
2017-05-12 2017-03-31 13F CYTOMX THERAPEUTICS COM 23284F105 231,984 -2,522 -1.08 4,006 55.45 0.0012
2017-02-13 2016-12-31 13F CYTOMX THERAPEUTICS COM 23284F105 234,506 18,182 8.40 2,577 -24.00 0.0008
2016-11-09 2016-09-30 13F CYTOMX THERAPEUTICS COM 23284F105 216,324 116,552 116.82 3,391 232.78 0.0011
2016-08-12 2016-06-30 13F CYTOMX THERAPEUTICS COM 23284F105 99,772 26,055 35.34 1,019 7.15 0.0003
2016-08-19 2016-03-31 13F/A-1 CYTOMX THERAPEUTICS COM 23284F105 73,717 258 0.35 951 -37.96 0.0003
2016-05-13 2016-03-31 13F CYTOMX THERAPEUTICS COM 23284F105 73,717 951
2016-02-12 2015-12-31 13F CYTOMX THERAPEUTICS COM 23284F105 73,459 73,459 1,533 0.0005
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.