Cue Biopharma, Inc.

SecurityCUE / Cue Biopharma, Inc.
InstitutionMorgan Stanley
Latest Disclosed Ownership18,374 shares
Latest Disclosed Value $ 4,224
Morgan Stanley reports 1.18% decrease in ownership of CUE / Cue Biopharma, Inc.

On May 15, 2026 - Morgan Stanley filed a 13F-HR form disclosing ownership of 18,374 shares of Cue Biopharma, Inc. (US:CUE) valued at $4,224 USD as of March 31, 2026. The entity filed a previous 13F-HR/A on May 27, 2026 disclosing 18,594 shares of Cue Biopharma, Inc.. This represents a change in shares of -1.18% during the quarter. The current value of the position is $494,444 USD.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date		 Effective
Date		Form Security Class ID Avg Price
Paid (Est)		 Reported
Shares		 ΔShares ΔShares
(%)		 Reported
Value
(x1000)		 ΔValue
(%)		 Alloc
(%)		 ΔAlloc ΔAlloc (%) Cost Basis
(x1000)		 Unrealized
Gain/Loss
(x1000)
2026-05-15 2026-03-31 13F CUE BIOPHARMA COM 22978P106 18,374 -220 -1.18 4 -20.00 0.0000
2026-05-27 2025-12-31 13F/A-1 CUE BIOPHARMA COM 22978P106 18,594 -8,918 -32.41 6 -73.68 0.0000
2026-02-13 2025-12-31 13F CUE BIOPHARMA COM 22978P106 18,594 -8,918 6 0.0000
2026-05-27 2025-09-30 13F/A-1 CUE BIOPHARMA COM 22978P106 27,512 -1,940 -6.59 20 -5.00 0.0000
2025-11-14 2025-09-30 13F CUE BIOPHARMA COM 22978P106 27,512 -1,940 20 0.0000
2025-08-15 2025-06-30 13F CUE BIOPHARMA COM 22978P106 29,452 760 2.65 20 -23.08 0.0000
2025-05-15 2025-03-31 13F CUE BIOPHARMA COM 22978P106 28,692 -1 -0.00 26 -16.13 0.0000
2025-05-15 2024-12-31 13F/A-1 CUE BIOPHARMA COM 22978P106 28,693 -4,999 -14.84 31 24.00 0.0000
2025-02-14 2024-12-31 13F CUE BIOPHARMA COM 22978P106 28,693 -4,999 31 0.0000
2025-05-14 2024-09-30 13F/A-2 CUE BIOPHARMA COM 22978P106 33,692 -87,307 -72.16 26 -83.33 0.0000
2025-02-14 2024-09-30 13F/A-1 CUE BIOPHARMA COM 22978P106 33,692 -87,307 26 0.0000
2024-11-14 2024-09-30 13F CUE BIOPHARMA COM 22978P106 33,692 -87,307 26 0.0000
2025-05-14 2024-06-30 13F/A-2 CUE BIOPHARMA COM 22978P106 120,999 -28,877 -19.27 150 -47.00 0.0000
2024-10-17 2024-06-30 13F/A-1 CUE BIOPHARMA COM 22978P106 120,999 -28,877 150 0.0000
2024-08-14 2024-06-30 13F CUE BIOPHARMA COM 22978P106 120,999 -28,877 150 0.0000
2024-10-17 2024-03-31 13F/A-2 CUE BIOPHARMA COM 22978P106 149,876 -14,830 -9.00 283 -34.79 0.0000
2024-08-16 2024-03-31 13F/A-1 CUE BIOPHARMA COM 22978P106 149,876 -14,830 283 0.0000
2024-05-15 2024-03-31 13F CUE BIOPHARMA COM 22978P106 149,876 -14,830 283 0.0000
2024-08-16 2023-12-31 13F/A-1 CUE BIOPHARMA COM 22978P106 164,706 40,168 32.25 435 51.75 0.0000
2024-02-13 2023-12-31 13F CUE BIOPHARMA COM 22978P106 164,706 40,168 435 0.0000
2023-11-15 2023-09-30 13F CUE BIOPHARMA COM 22978P106 124,538 18,725 17.70 286 -25.91 0.0000
2023-08-14 2023-06-30 13F CUE BIOPHARMA COM 22978P106 105,813 6,888 6.96 386 9.35 0.0000
2023-05-15 2023-03-31 13F CUE BIOPHARMA COM 22978P106 98,925 -79,871 -44.67 353 -30.65 0.0000
2023-02-14 2022-12-31 13F CUE BIOPHARMA COM 22978P106 178,796 -76,512 -29.97 510 -10.54 0.0001
2022-11-14 2022-09-30 13F CUE BIOPHARMA COM 22978P106 255,308 -180,274 -41.39 569 -47.56 0.0001
2022-10-27 2022-06-30 13F/A-1 CUE BIOPHARMA COM 22978P106 435,582 237,003 119.35 1,085 11.97 0.0001
2022-08-15 2022-06-30 13F CUE BIOPHARMA COM 22978P106 435,582 237,003 1,085 0.0000
2022-10-27 2022-03-31 13F/A-1 CUE BIOPHARMA COM 22978P106 198,579 21,760 12.31 969 -51.55 0.0001
2022-05-13 2022-03-31 13F CUE BIOPHARMA COM 22978P106 198,579 21,760 969 0.0001
2022-02-14 2021-12-31 13F CUE BIOPHARMA COM 22978P106 176,819 -297,412 -62.71 2,000 -71.06 0.0002
2021-11-15 2021-09-30 13F CUE BIOPHARMA COM 22978P106 474,231 46,876 10.97 6,910 38.81 0.0009
2021-08-23 2021-06-30 13F/A-1 CUE BIOPHARMA COM 22978P106 427,355 108,236 33.92 4,978 27.84 0.0007
2021-08-16 2021-06-30 13F CUE BIOPHARMA COM 22978P106 427,355 108,236 4,978 0.0001
2021-05-17 2021-03-31 13F CUE BIOPHARMA COM 22978P106 319,119 -224,943 -41.35 3,894 -42.79 0.0006
2021-02-16 2020-12-31 13F CUE BIOPHARMA COM 22978P106 544,062 302,995 125.69 6,806 87.60 0.0011
2020-11-13 2020-09-30 13F CUE BIOPHARMA COM 22978P106 241,067 103,360 75.06 3,628 7.50 0.0007
2020-08-14 2020-06-30 13F CUE BIOPHARMA COM 22978P106 137,707 98,505 251.28 3,375 507.01 0.0007
2020-05-26 2020-03-31 13F/A-1 CUE BIOPHARMA COM 22978P106 39,202 -36,826 -48.44 556 -53.94 0.0002
2020-05-15 2020-03-31 13F CUE BIOPHARMA COM 22978P106 39,202 -36,826 556 42.7124
2020-02-14 2019-12-31 13F CUE BIOPHARMA COM 22978P106 76,028 47,513 166.62 1,207 402.92 0.0003
2019-11-14 2019-09-30 13F CUE BIOPHARMA COM 22978P106 28,515 6,789 31.25 240 22.45 0.0001
2019-08-14 2019-06-30 13F CUE BIOPHARMA COM 22978P106 21,726 718 3.42 196 20.99 0.0001
2019-05-15 2019-03-31 13F CUE BIOPHARMA COM 22978P106 21,008 -27,529 -56.72 162 -28.95 0.0000
2019-02-14 2018-12-31 13F CUE BIOPHARMA COM 22978P106 48,537 -31,487 -39.35 228 -68.55 0.0001
2019-04-23 2018-09-30 13F/A-2 CUE BIOPHARMA COM 22978P106 80,024 39,212 96.08 725 49.79 0.0002
2018-11-20 2018-09-30 13F/A-1 CUE BIOPHARMA COM 22978P106 80,024 0 725 0.0002
2018-11-14 2018-09-30 13F CUE BIOPHARMA COM 22978P106 80,024 39,212 725
2019-04-23 2018-06-30 13F/A-1 CUE BIOPHARMA COM 22978P106 40,812 17,505 75.11 484 48.01 0.0001
2018-08-14 2018-06-30 13F CUE BIOPHARMA COM 22978P106 40,812 17,505 484
2019-04-23 2018-03-31 13F/A-1 CUE BIOPHARMA COM 22978P106 23,307 23,307 327 0.0001
2018-05-14 2018-03-31 13F CUE BIOPHARMA COM 22978P106 23,307 327 0.0001
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.