Cytokinetics, Incorporated
US ˙ NasdaqGS ˙ US23282W6057

SecurityCYTK / Cytokinetics, Incorporated
InstitutionNorthern Trust Corp
Latest Disclosed Ownership1,441,634 shares
Latest Disclosed Value $ 95,018,097
Northern Trust Corp reports 4.41% increase in ownership of CYTK / Cytokinetics, Incorporated

On May 14, 2026 - Northern Trust Corp filed a 13F-HR form disclosing ownership of 1,441,634 shares of Cytokinetics, Incorporated (US:CYTK) valued at $95,018,097 USD as of March 31, 2026. The entity filed a previous 13F-HR on February 17, 2026 disclosing 1,380,787 shares of Cytokinetics, Incorporated. This represents a change in shares of 4.41% during the quarter. The current value of the position is $104,215,722 USD.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date		 Effective
Date		Form Security Class ID Avg Price
Paid (Est)		 Reported
Shares		 ΔShares ΔShares
(%)		 Reported
Value
(x1000)		 ΔValue
(%)		 Alloc
(%)		 ΔAlloc ΔAlloc (%) Cost Basis
(x1000)		 Unrealized
Gain/Loss
(x1000)
2026-05-14 2026-03-31 13F CYTOKINETICS COM NEW 23282W605 1,441,634 60,847 4.41 95,018 8.30 0.0026
2026-02-17 2025-12-31 13F CYTOKINETICS COM NEW 23282W605 1,380,787 -26,045 -1.85 87,735 13.47 0.0023
2025-11-14 2025-09-30 13F CYTOKINETICS COM NEW 23282W605 1,406,832 27,641 2.00 77,319 69.68 0.0099
2025-08-13 2025-06-30 13F CYTOKINETICS COM NEW 23282W605 1,379,191 -68,125 -4.71 45,568 -21.66 0.0063
2025-05-13 2025-03-31 13F CYTOKINETICS COM NEW 23282W605 1,447,316 -24,173 -1.64 58,168 -15.97 0.0086
2025-02-14 2024-12-31 13F CYTOKINETICS COM NEW 23282W605 1,471,489 141,835 10.67 69,219 -1.41 0.0098
2024-11-13 2024-09-30 13F CYTOKINETICS COM 23282W605 1,329,654 46,761 3.64 70,206 1.00 0.0115
2024-08-14 2024-06-30 13F CYTOKINETICS COM 23282W605 1,282,893 171,453 15.43 69,507 -10.80 0.0117
2024-05-14 2024-03-31 13F CYTOKINETICS COM 23282W605 1,111,440 55,463 5.25 77,923 -11.61 0.0135
2024-02-13 2023-12-31 13F CYTOKINETICS COM 23282W605 1,055,977 -17,268 -1.61 88,164 178.85 0.0160
2023-11-13 2023-09-30 13F CYTOKINETICS COM 23282W605 1,073,245 -26,088 -2.37 31,618 -11.83 0.0061
2023-08-11 2023-06-30 13F CYTOKINETICS COM 23282W605 1,099,333 88,408 8.75 35,860 0.80 0.0069
2023-05-15 2023-03-31 13F CYTOKINETICS COM 23282W605 1,010,925 128 0.01 35,574 -23.19 0.0071
2023-02-13 2022-12-31 13F CYTOKINETICS COM 23282W605 1,010,797 18,446 1.86 46,315 -3.67 0.0097
2022-11-14 2022-09-30 13F CYTOKINETICS COM 23282W605 992,351 20,685 2.13 48,080 25.94 0.0110
2022-08-12 2022-06-30 13F CYTOKINETICS COM 23282W605 971,666 6,879 0.71 38,176 7.50 0.0082
2022-05-13 2022-03-31 13F CYTOKINETICS COM 23282W605 964,787 -44,558 -4.41 35,513 -22.81 0.0062
2022-02-08 2021-12-31 13F CYTOKINETICS COM NEW 23282W605 1,009,345 -595 -0.06 46,007 27.46 0.0075
2021-11-15 2021-09-30 13F CYTOKINETICS COM 23282W605 1,009,940 102,360 11.28 36,095 100.95 0.0064
2021-08-13 2021-06-30 13F CYTOKINETICS COM NEW 23282W605 907,580 97,399 12.02 17,962 -4.68 0.0032
2021-05-12 2021-03-31 13F CYTOKINETICS COM NEW 23282W605 810,181 -27,276 -3.26 18,844 8.28 0.0035
2021-02-11 2020-12-31 13F CYTOKINETICS COM NEW 23282W605 837,457 -40,479 -4.61 17,403 -8.43 0.0034
2020-11-16 2020-09-30 13F CYTOKINETICS COM NEW 23282W605 877,936 82,571 10.38 19,006 1.38 0.0042
2020-08-14 2020-06-30 13F CYTOKINETICS COM 23282W605 795,365 22,057 2.85 18,747 105.60 0.0044
2020-05-14 2020-03-31 13F CYTOKINETICS COM NEW 23282W605 773,308 7,900 1.03 9,118 12.28 0.0026
2020-02-14 2019-12-31 13F CYTOKINETICS COM NEW 23282W605 765,408 -25,210 -3.19 8,121 -9.74 0.0018
2019-11-13 2019-09-30 13F CYTOKINETICS COM 23282W605 790,618 113,633 16.79 8,997 18.13 0.0022
2019-08-13 2019-06-30 13F CYTOKINETICS COM NEW 23282W605 676,985 133,189 24.49 7,616 73.09 0.0018
2019-05-13 2019-03-31 13F CYTOKINETICS COM NEW 23282W605 543,796 11,469 2.15 4,400 30.80 0.0011
2019-02-12 2018-12-31 13F CYTOKINETICS COM NEW 23282W605 532,327 -12,987 -2.38 3,364 -37.36 0.0009
2018-11-14 2018-09-30 13F CYTOKINETICS COM NEW 23282W605 545,314 46,768 9.38 5,370 29.77 0.0013
2018-09-18 2018-06-30 13F/A-1 CYTOKINETICS COM NEW 23282W605 498,546 71,418 16.72 4,138 34.57 0.0011
2018-08-14 2018-06-30 13F CYTOKINETICS COM NEW 23282W605 501,950 74,822 4,166
2018-05-09 2018-03-31 13F CYTOKINETICS COM 23282W605 427,128 675 0.16 3,075 -11.54 0.0008
2018-02-14 2017-12-31 13F CYTOKINETICS COM 23282W605 426,453 -45,405 -9.62 3,476 -49.20 0.0009
2017-11-13 2017-09-30 13F CYTOKINETICS COM 23282W605 471,858 4,546 0.97 6,843 21.01 0.0018
2017-08-11 2017-06-30 13F CYTOKINETICS COM 23282W605 467,312 86,885 22.84 5,655 15.67 0.0016
2017-05-12 2017-03-31 13F CYTOKINETICS COM 23282W605 380,427 5,645 1.51 4,889 7.36 0.0014
2017-02-13 2016-12-31 13F CYTOKINETICS COM 23282W605 374,782 18,235 5.11 4,554 39.14 0.0014
2016-11-09 2016-09-30 13F CYTOKINETICS COM 23282W605 356,547 52,561 17.29 3,273 13.45 0.0010
2016-08-12 2016-06-30 13F CYTOKINETICS COM 23282W605 303,986 -113,203 -27.13 2,885 -1.94 0.0009
2016-08-19 2016-03-31 13F/A-1 CYTOKINETICS COM 23282W605 417,189 43,846 11.74 2,942 -24.68 0.0010
2016-05-13 2016-03-31 13F CYTOKINETICS COM 23282W605 417,189 2,942
2016-02-12 2015-12-31 13F CYTOKINETICS COM 23282W605 373,343 23,191 6.62 3,906 66.78 0.0013
2015-11-12 2015-09-30 13F CYTOKINETICS COM 23282W605 350,152 17,175 5.16 2,342 4.65 0.0008
2015-08-13 2015-06-30 13F CYTOKINETICS COM 23282W605 332,977 2,102 0.64 2,238 -0.22 0.0015
2015-05-14 2015-03-31 13F CYTOKINETICS COM 23282W605 330,875 1,164 0.35 2,243 -15.07 0.0007
2015-02-12 2014-12-31 13F CYTOKINETICS COM 23282W605 329,711 -17,837 -5.13 2,641 115.77 0.0008
2014-11-13 2014-09-30 13F CYTOKINETICS COM 23282W605 347,548 2,513 0.73 1,224 -25.77 0.0004
2014-08-14 2014-06-30 13F CYTOKINETICS COM 23282W605 345,035 -2,004 -0.58 1,649 -49.98 0.0005
2014-05-14 2014-03-31 13F CYTOKINETICS COM 23282W605 347,039 -4,692 -1.33 3,297 44.23 0.0010
2014-02-21 2013-12-31 13F/A-1 CYTOKINETICS COM 23282W605 351,731 13,569 4.01 2,286 -10.70 0.0007
2014-02-12 2013-12-31 13F CYTOKINETICS COM 23282W605 351,731 2,286
2013-11-13 2013-09-30 13F CYTOKINETICS COM 23282W605 338,162 338,162 2,560 0.0009
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.