Cytokinetics, Incorporated
US ˙ NasdaqGS ˙ US23282W6057

SecurityCYTK / Cytokinetics, Incorporated
InstitutionSei Investments Co
Latest Disclosed Ownership70,239 shares
Latest Disclosed Value $ 4,462,958
Sei Investments Co reports 2.13% increase in ownership of CYTK / Cytokinetics, Incorporated

On February 13, 2026 - Sei Investments Co filed a 13F-HR form disclosing ownership of 70,239 shares of Cytokinetics, Incorporated (US:CYTK) valued at $4,462,986 USD as of December 31, 2025. The entity filed a previous 13F-HR on November 13, 2025 disclosing 68,772 shares of Cytokinetics, Incorporated. This represents a change in shares of 2.13% during the quarter. The current value of the position is $5,077,577 USD.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date		 Effective
Date		Form Security Class ID Avg Price
Paid (Est)		 Reported
Shares		 ΔShares ΔShares
(%)		 Reported
Value
(x1000)		 ΔValue
(%)		 Alloc
(%)		 ΔAlloc ΔAlloc (%) Cost Basis
(x1000)		 Unrealized
Gain/Loss
(x1000)
2026-02-13 2025-12-31 13F CYTOKINETICS COM NEW 23282W605 70,239 1,467 2.13 4,463 18.07 0.0044
2025-11-13 2025-09-30 13F CYTOKINETICS COM NEW 23282W605 68,772 12,367 21.93 3,780 102.84 0.0041
2025-08-14 2025-06-30 13F CYTOKINETICS COM NEW 23282W605 56,405 -34,945 -38.25 1,864 -49.25 0.0022
2025-05-14 2025-03-31 13F/A-1 CYTOKINETICS COM NEW 23282W605 91,350 1,790 2.00 3,671 -12.84 0.0047
2025-05-13 2025-03-31 13F CYTOKINETICS COM NEW 23282W605 89,576 16 4,213 0.0046
2025-02-11 2024-12-31 13F CYTOKINETICS COM NEW 23282W605 89,560 -1,472 -1.62 4,213 -12.36 0.0054
2024-11-12 2024-09-30 13F CYTOKINETICS COM NEW 23282W605 91,032 28,023 44.47 4,806 40.81 0.0062
2024-08-13 2024-06-30 13F CYTOKINETICS COM NEW 23282W605 63,009 4,695 8.05 3,414 -16.51 0.0048
2024-05-07 2024-03-31 13F CYTOKINETICS COM NEW 23282W605 58,314 9,779 20.15 4,088 0.89 0.0060
2024-02-14 2023-12-31 13F CYTOKINETICS COM NEW 23282W605 48,535 -9,088 -15.77 4,052 138.77 0.0065
2023-11-14 2023-09-30 13F CYTOKINETICS COM NEW 23282W605 57,623 3,358 6.19 1,698 -4.12 0.0031
2023-08-11 2023-06-30 13F CYTOKINETICS COM NEW 23282W605 54,265 -39,118 -41.89 1,770 -46.14 0.0031
2023-05-12 2023-03-31 13F CYTOKINETICS COM NEW 23282W605 93,383 62,758 204.92 3,286 134.21 0.0061
2023-02-10 2022-12-31 13F CYTOKINETICS COM NEW 23282W605 30,625 -83,256 -73.11 1,403 -74.57 0.0031
2022-11-14 2022-09-30 13F CYTOKINETICS COM NEW 23282W605 113,881 10,112 9.74 5,518 35.31 0.0123
2022-08-15 2022-06-30 13F CYTOKINETICS COM NEW 23282W605 103,769 34,329 49.44 4,078 59.55 0.0088
2022-05-13 2022-03-31 13F CYTOKINETICS COM NEW 23282W605 69,440 -4,895 -6.59 2,556 -24.67 0.0051
2022-02-14 2021-12-31 13F CYTOKINETICS COM NEW 23282W605 74,335 -2,136 -2.79 3,393 24.15 0.0064
2021-11-12 2021-09-30 13F CYTOKINETICS COM NEW 23282W605 76,471 46,054 151.41 2,733 360.88 0.0057
2021-08-06 2021-06-30 13F CYTOKINETICS COM NEW 23282W605 30,417 574 1.92 593 -14.55 0.0013
2021-05-12 2021-03-31 13F CYTOKINETICS COM NEW 23282W605 29,843 -3,432 -10.31 694 0.43 0.0017
2021-02-08 2020-12-31 13F CYTOKINETICS COM NEW 23282W605 33,275 33,275 691 0.0018
2020-12-04 2020-09-30 13F/A-1 CYTOKINETICS COM NEW 23282W605 0 -21,326 -100.00 0 -100.00
2020-08-17 2020-06-30 13F/A-1 CYTOKINETICS COM NEW 23282W605 21,326 21,326 503 0.0016
2020-08-11 2020-06-30 13F CYTOKINETICS COM NEW 23282W605 21,326 21,326 503 1,364.4143
2018-05-11 2018-03-31 13F CYTOKINETICS COM NEW 23282W605 0 -14 -100.00 0 0.0000
2018-02-08 2017-12-31 13F CYTOKINETICS COM NEW 23282W605 14 -9 -39.13 0 0.0000
2017-05-05 2017-03-31 13F CYTOKINETICS COM NEW 23282W605 23 23 0 0.0000
2016-05-10 2016-03-31 13F/A-1 CYTOKINETICS COM NEW 23282W605 0 -109 -100.00 0 -100.00
2016-02-03 2015-12-31 13F CYTOKINETICS COM NEW 23282W605 109 29 36.25 1 0.00 0.0000
2015-11-02 2015-09-30 13F/A-1 CYTOKINETICS COM NEW 23282W605 80 80 1 0.0000
2015-10-30 2015-09-30 13F CYTOKINETICS COM NEW 23282W605 80 1
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.