Enliven Therapeutics, Inc.
US ˙ NasdaqGS ˙ US29337E1029

SecurityELVN / Enliven Therapeutics, Inc.
InstitutionJanus Henderson Group Plc
Latest Disclosed Ownership11,000 shares
Latest Disclosed Value $ 431,200
Janus Henderson Group Plc reports 99.34% decrease in ownership of ELVN / Enliven Therapeutics, Inc.

On May 18, 2026 - Janus Henderson Group Plc filed a 13F-HR/A form disclosing ownership of 11,000 shares of Enliven Therapeutics, Inc. (US:ELVN) valued at $431,200 USD as of March 31, 2026. The entity filed a previous 13F-HR on February 17, 2026 disclosing 1,671,724 shares of Enliven Therapeutics, Inc.. This represents a change in shares of -99.34% during the quarter. The current value of the position is $381,810 USD.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date
Effective
Date
Form Security Class ID Avg Price
Paid (Est)
Reported
Shares
ΔShares ΔShares
(%)
Reported
Value
(x1000)
ΔValue
(%)
Alloc
(%)
ΔAlloc ΔAlloc (%) Cost Basis
(x1000)
Unrealized
Gain/Loss
(x1000)
2026-05-18 2026-03-31 13F/A-1 ENLIVEN THERAPEUTICS COM 29337E102 11,000 -1,660,724 -99.34 431 -98.33 0.0001
2026-05-15 2026-03-31 13F ENLIVEN THERAPEUTICS COM 29337E102 11,000 -1,660,724 431 0.0001
2026-02-17 2025-12-31 13F ENLIVEN THERAPEUTICS COM 29337E102 1,671,724 -121,859 -6.79 25,745 -29.85 0.0115
2025-11-14 2025-09-30 13F ENLIVEN THERAPEUTICS COM 29337E102 1,793,583 77,171 4.50 36,697 6.63 0.0168
2025-08-14 2025-06-30 13F ENLIVEN THERAPEUTICS COM 29337E102 1,716,412 145,909 9.29 34,414 4.12 0.0169
2025-05-15 2025-03-31 13F ENLIVEN THERAPEUTICS COM 29337E102 1,570,503 238,626 17.92 33,051 10.17 0.0181
2025-02-14 2024-12-31 13F ENLIVEN THERAPEUTICS COM 29337E102 1,331,877 290,153 27.85 30,001 12.74 0.0152
2024-11-14 2024-09-30 13F ENLIVEN THERAPEUTICS COM 29337E102 1,041,724 313,019 42.96 26,611 56.43 0.0136
2024-08-14 2024-06-30 13F ENLIVEN THERAPEUTICS COM 29337E102 728,705 14,794 2.07 17,012 34.97 0.0091
2024-05-15 2024-03-31 13F ENLIVEN THERAPEUTICS COM 29337E102 713,911 305,397 74.76 12,604 122.06 0.0069
2024-02-14 2023-12-31 13F ENLIVEN THERAPEUTICS COM 29337E102 408,514 132,098 47.79 5,676 50.64 0.0034
2023-11-14 2023-09-30 13F ENLIVEN THERAPEUTICS COM 29337E102 276,416 -94,578 -25.49 3,769 -50.22 0.0025
2023-08-14 2023-06-30 13F ENLIVEN THERAPEUTICS COM 29337E102 370,994 -231,160 -38.39 7,570 -42.58 0.0047
2023-05-15 2023-03-31 13F ENLIVEN THERAPEUTICS COM 29337E102 602,154 602,154 13,183 0.0087
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.