Heron Therapeutics, Inc.
US ˙ NasdaqCM ˙ US4277461020

SecurityHRTX / Heron Therapeutics, Inc.
InstitutionMorgan Stanley
Latest Disclosed Ownership513,413 shares
Latest Disclosed Value $ 410,781
Morgan Stanley reports 46.73% decrease in ownership of HRTX / Heron Therapeutics, Inc.

On May 15, 2026 - Morgan Stanley filed a 13F-HR form disclosing ownership of 513,413 shares of Heron Therapeutics, Inc. (US:HRTX) valued at $410,782 USD as of March 31, 2026. The entity filed a previous 13F-HR/A on May 27, 2026 disclosing 963,851 shares of Heron Therapeutics, Inc.. This represents a change in shares of -46.73% during the quarter. The current value of the position is $248,235 USD.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date		 Effective
Date		Form Security Class ID Avg Price
Paid (Est)		 Reported
Shares		 ΔShares ΔShares
(%)		 Reported
Value
(x1000)		 ΔValue
(%)		 Alloc
(%)		 ΔAlloc ΔAlloc (%) Cost Basis
(x1000)		 Unrealized
Gain/Loss
(x1000)
2026-05-15 2026-03-31 13F HERON THERAPEUTICS COM 427746102 513,413 -450,438 -46.73 411 -67.28 0.0000
2026-05-27 2025-12-31 13F/A-1 HERON THERAPEUTICS COM 427746102 963,851 -1,504,190 -60.95 1,253 -59.70 0.0001
2026-02-13 2025-12-31 13F HERON THERAPEUTICS COM 427746102 963,851 -1,504,190 1,253 0.0001
2026-05-27 2025-09-30 13F/A-1 HERON THERAPEUTICS COM 427746102 2,468,041 -293,550 -10.63 3,110 -45.61 0.0002
2025-11-14 2025-09-30 13F HERON THERAPEUTICS COM 427746102 2,468,041 -293,550 3,110 0.0002
2025-08-15 2025-06-30 13F HERON THERAPEUTICS COM 427746102 2,761,591 828,186 42.84 5,716 34.40 0.0004
2025-05-15 2025-03-31 13F HERON THERAPEUTICS COM 427746102 1,933,405 -860,785 -30.81 4,253 -0.51 0.0003
2025-05-15 2024-12-31 13F/A-1 HERON THERAPEUTICS COM 427746102 2,794,190 1,025,837 58.01 4,275 21.48 0.0003
2025-02-14 2024-12-31 13F HERON THERAPEUTICS COM 427746102 2,794,190 1,025,837 4,275 0.0003
2025-05-14 2024-09-30 13F/A-2 HERON THERAPEUTICS COM 427746102 1,768,353 1,000,492 130.30 3,519 30.96 0.0003
2025-02-14 2024-09-30 13F/A-1 HERON THERAPEUTICS COM 427746102 1,768,353 1,000,492 3,519 0.0003
2024-11-14 2024-09-30 13F HERON THERAPEUTICS COM 427746102 1,768,353 1,000,492 3,519 0.0000
2025-05-14 2024-06-30 13F/A-2 HERON THERAPEUTICS COM 427746102 767,861 568,862 285.86 2,688 387.66 0.0002
2024-10-17 2024-06-30 13F/A-1 HERON THERAPEUTICS COM 427746102 767,861 568,862 2,688 0.0002
2024-08-14 2024-06-30 13F HERON THERAPEUTICS COM 427746102 767,861 568,862 2,688 0.0002
2024-10-17 2024-03-31 13F/A-2 HERON THERAPEUTICS COM 427746102 198,999 -263,149 -56.94 551 -29.81 0.0000
2024-08-16 2024-03-31 13F/A-1 HERON THERAPEUTICS COM 427746102 198,999 -263,149 551 0.0000
2024-05-15 2024-03-31 13F HERON THERAPEUTICS COM 427746102 198,999 -263,149 551 0.0000
2024-08-16 2023-12-31 13F/A-1 HERON THERAPEUTICS COM 427746102 462,148 26,641 6.12 786 75.22 0.0001
2024-02-13 2023-12-31 13F HERON THERAPEUTICS COM 427746102 462,148 26,641 786 0.0001
2023-11-15 2023-09-30 13F HERON THERAPEUTICS COM 427746102 435,507 58,237 15.44 449 2.52 0.0000
2023-08-14 2023-06-30 13F HERON THERAPEUTICS COM 427746102 377,270 -78,727 -17.26 438 -36.48 0.0000
2023-05-15 2023-03-31 13F HERON THERAPEUTICS COM 427746102 455,997 -355,904 -43.84 689 -66.09 0.0001
2023-02-14 2022-12-31 13F HERON THERAPEUTICS COM 427746102 811,901 -134,412 -14.20 2,030 -49.20 0.0002
2022-11-14 2022-09-30 13F HERON THERAPEUTICS COM 427746102 946,313 -1,091,582 -53.56 3,994 -29.74 0.0005
2022-10-27 2022-06-30 13F/A-1 HERON THERAPEUTICS COM 427746102 2,037,895 567,067 38.55 5,685 -32.42 0.0007
2022-08-15 2022-06-30 13F HERON THERAPEUTICS COM 427746102 2,037,895 567,067 5,685 0.0007
2022-10-27 2022-03-31 13F/A-1 HERON THERAPEUTICS COM 427746102 1,470,828 1,178,629 403.37 8,412 215.41 0.0011
2022-05-13 2022-03-31 13F HERON THERAPEUTICS COM 427746102 1,470,828 1,178,629 8,412 0.0011
2022-02-14 2021-12-31 13F HERON THERAPEUTICS COM 427746102 292,199 -72,570 -19.89 2,667 -31.60 0.0003
2021-11-15 2021-09-30 13F HERON THERAPEUTICS COM 427746102 364,769 -155,629 -29.91 3,899 -51.73 0.0005
2021-08-23 2021-06-30 13F/A-1 HERON THERAPEUTICS COM 427746102 520,398 -98,330 -15.89 8,077 -19.47 0.0011
2021-08-16 2021-06-30 13F HERON THERAPEUTICS COM 427746102 520,398 -98,330 8,077 0.0002
2021-05-17 2021-03-31 13F HERON THERAPEUTICS COM 427746102 618,728 158,965 34.58 10,030 3.07 0.0015
2021-02-16 2020-12-31 13F HERON THERAPEUTICS COM 427746102 459,763 271,879 144.71 9,731 249.66 0.0015
2020-11-13 2020-09-30 13F HERON THERAPEUTICS COM 427746102 187,884 96,089 104.68 2,783 106.30 0.0005
2020-08-14 2020-06-30 13F HERON THERAPEUTICS COM 427746102 91,795 -429,386 -82.39 1,349 -77.95 0.0003
2020-05-26 2020-03-31 13F/A-1 HERON THERAPEUTICS COM 427746102 521,181 325,758 166.69 6,118 33.23 0.0017
2020-05-15 2020-03-31 13F HERON THERAPEUTICS COM 427746102 521,181 325,758 6,118 469.9899
2020-02-14 2019-12-31 13F HERON THERAPEUTICS COM 427746102 195,423 127,508 187.75 4,592 265.31 0.0011
2019-11-14 2019-09-30 13F HERON THERAPEUTICS COM 427746102 67,915 29,977 79.02 1,257 78.30 0.0003
2019-08-14 2019-06-30 13F HERON THERAPEUTICS COM 427746102 37,938 -26,308 -40.95 705 -55.12 0.0002
2019-05-15 2019-03-31 13F HERON THERAPEUTICS COM 427746102 64,246 -365,531 -85.05 1,571 -85.91 0.0004
2019-02-14 2018-12-31 13F HERON THERAPEUTICS COM 427746102 429,777 262,171 156.42 11,149 110.16 0.0033
2019-04-23 2018-09-30 13F/A-2 HERON THERAPEUTICS COM 427746102 167,606 -196,396 -53.95 5,305 -62.49 0.0013
2018-11-20 2018-09-30 13F/A-1 HERON THERAPEUTICS COM 427746102 167,606 0 5,305 0.0013
2018-11-14 2018-09-30 13F HERON THERAPEUTICS COM 427746102 167,606 -196,396 5,305
2019-04-23 2018-06-30 13F/A-1 HERON THERAPEUTICS COM 427746102 364,002 213,862 142.44 14,142 241.26 0.0038
2018-08-14 2018-06-30 13F HERON THERAPEUTICS COM 427746102 364,002 213,862 14,142
2019-04-23 2018-03-31 13F/A-1 HERON THERAPEUTICS COM 427746102 150,140 11,464 8.27 4,144 65.10 0.0012
2018-05-14 2018-03-31 13F HERON THERAPEUTICS COM 427746102 150,140 11,464 4,144
2019-04-23 2017-12-31 13F/A-1 HERON THERAPEUTICS COM 427746102 138,676 66,633 92.49 2,510 115.82 0.0007
2018-02-14 2017-12-31 13F HERON THERAPEUTICS COM 427746102 138,676 66,633 2,510
2017-11-14 2017-09-30 13F HERON THERAPEUTICS COM 427746102 72,043 -29,030 -28.72 1,163 -16.93 0.0003
2017-08-11 2017-06-30 13F HERON THERAPEUTICS COM 427746102 101,073 1,040 1.04 1,400 -6.73 0.0004
2017-05-22 2017-03-31 13F/A-1 HERON THERAPEUTICS COM 427746102 100,033 -56,840 -36.23 1,501 -26.92 0.0005
2017-05-12 2017-03-31 13F HERON THERAPEUTICS COM 427746102 100,033 1,501
2017-02-22 2016-12-31 13F/A-1 HERON THERAPEUTICS COM 427746102 156,873 72,859 86.72 2,054 41.85 0.0007
2017-02-13 2016-12-31 13F HERON THERAPEUTICS COM 427746102 156,873 2,054
2016-11-10 2016-09-30 13F HERON THERAPEUTICS COM 427746102 84,014 61,210 268.42 1,448 252.31 0.0005
2016-08-12 2016-06-30 13F HERON THERAPEUTICS COM 427746102 22,804 13,546 146.32 411 134.86 0.0001
2016-05-12 2016-03-31 13F HERON THERAPEUTICS COM 427746102 9,258 -42,915 -82.26 175 -87.44 0.0001
2016-02-09 2015-12-31 13F HERON THERAPEUTICS COM 427746102 52,173 -26,324 -33.54 1,393 -27.26 0.0005
2016-02-08 2015-09-30 13F/A-1 HERON THERAPEUTICS COM 427746102 78,497 -150,465 -65.72 1,915 -73.16 0.0007
2015-11-09 2015-09-30 13F HERON THERAPEUTICS COM 427746102 78,497 1,915
2015-08-12 2015-06-30 13F HERON THERAPEUTICS COM 427746102 228,962 -59,840 -20.72 7,135 69.76 0.0025
2015-05-14 2015-03-31 13F HERON THERAPEUTICS COM 427746102 288,802 267,192 1,236.43 4,203 1,836.87 0.0015
2015-02-13 2014-12-31 13F HERON THERAPEUTICS COM 427746102 21,610 17,872 478.12 217 578.13 0.0001
2014-12-16 2014-09-30 13F/A-1 HERON THERAPEUTICS COM 427746102 3,738 -113,023 -96.80 32 -98.03 0.0000
2014-11-14 2014-09-30 13F HERON THERAPEUTICS COM 427746102 3,738 32
2014-05-13 2014-03-31 13F HERON THERAPEUTICS COM 427746102 116,761 116,761 1,624 0.0007
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.