Illumina, Inc.
US ˙ NasdaqGS ˙ US4523271090

SecurityILMN / Illumina, Inc.
InstitutionSei Investments Co
Latest Disclosed Ownership91,309 shares
Latest Disclosed Value $ 11,975,788
Sei Investments Co ownership in ILMN / Illumina, Inc.

On February 13, 2026 - Sei Investments Co filed a 13F-HR form disclosing ownership of 91,309 shares of Illumina, Inc. (US:ILMN) valued at $11,976,088 USD as of December 31, 2025. The entity filed a previous 13F-HR on November 13, 2025 disclosing 85,376 shares of Illumina, Inc.. This represents a change in shares of 6.95% during the quarter. The current value of the position is $15,607,447 USD.

Sei Investments Co has a history of taking positions in derivatives of the underlying security (ILMN) in the form of stock options.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Institutional Put/Call Ratios
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In addition to reporting standard equity and debt issues, institutions with more than 100MM assets under management must also disclose their put and call option holdings. Since put options generally indicate negative sentiment, and call options indicate positive sentiment, we can get a sense of the overall institutional sentiment by plotting the ratio of puts to calls. The chart to the right plots the historical put/call ratio for this instrument.

Using Put/Call Ratio as an indicator of investor sentiment overcomes one of the key deficiencies of using total institutional ownership, which is that a significant amount of assets under management are invested passively to track indices. Passively-managed funds do not typically buy options, so the put/call ratio indicator more closely tracks the sentiment of actively-managed funds.

ILMN / Illumina, Inc. Historical Put/Call Ratio
Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date
Effective
Date
Form Security Class ID Avg Price
Paid (Est)
Reported
Shares
ΔShares ΔShares
(%)
Reported
Value
(x1000)
ΔValue
(%)
Alloc
(%)
ΔAlloc ΔAlloc (%) Cost Basis
(x1000)
Unrealized
Gain/Loss
(x1000)
2026-02-13 2025-12-31 13F ILLUMINA COM 452327109 91,309 5,933 6.95 11,976 47.78 0.0118
2025-11-13 2025-09-30 13F ILLUMINA COM 452327109 85,376 20,965 32.55 8,104 31.86 0.0087
2025-08-14 2025-06-30 13F ILLUMINA COM 452327109 64,411 -6,277 -8.88 6,145 9.58 0.0071
2025-05-14 2025-03-31 13F/A-1 ILLUMINA COM 452327109 70,688 -64,225 -47.60 5,608 -68.89 0.0072
2025-05-13 2025-03-31 13F ILLUMINA COM 452327109 133,703 -1,210 15,686 0.0171
2025-02-11 2024-12-31 13F ILLUMINA COM 452327109 134,913 4,738 3.64 18,028 6.21 0.0232
2024-11-12 2024-09-30 13F ILLUMINA COM 452327109 130,175 32,494 33.27 16,974 66.48 0.0220
2024-08-13 2024-06-30 13F ILLUMINA COM 452327109 97,681 26,538 37.30 10,196 4.37 0.0144
2024-05-07 2024-03-31 13F ILLUMINA COM 452327109 71,143 53,761 309.29 9,769 303.68 0.0143
2024-02-14 2023-12-31 13F ILLUMINA COM 452327109 17,382 -173,285 -90.88 2,421 -90.75 0.0039
2023-11-14 2023-09-30 13F ILLUMINA COM 452327109 190,667 -5,351 -2.73 26,174 -28.78 0.0470
2023-08-11 2023-06-30 13F ILLUMINA COM 452327109 196,018 -4,424 -2.21 36,750 -21.16 0.0641
2023-05-12 2023-03-31 13F ILLUMINA COM 452327109 200,442 14,434 7.76 46,614 23.94 0.0866
2023-02-10 2022-12-31 13F ILLUMINA COM 452327109 186,008 11,591 6.65 37,610 13.02 0.0836
2022-11-14 2022-09-30 13F ILLUMINA COM 452327109 174,417 82,567 89.89 33,276 97.19 0.0742
2022-08-15 2022-06-30 13F ILLUMINA COM 452327109 91,850 24,787 36.96 16,875 -27.81 0.0364
2022-05-13 2022-03-31 13F ILLUMINA COM 452327109 67,063 -3,385 -4.80 23,375 -12.68 0.0470
2022-02-14 2021-12-31 13F ILLUMINA COM 452327109 70,448 4,574 6.94 26,768 0.30 0.0502
2021-11-12 2021-09-30 13F ILLUMINA COM 452327109 65,874 -693 -1.04 26,688 -15.19 0.0560
2021-08-06 2021-06-30 13F ILLUMINA COM 452327109 66,567 15,975 31.58 31,469 61.97 0.0698
2021-05-12 2021-03-31 13F ILLUMINA COM 452327109 50,592 -33,298 -39.69 19,429 -37.40 0.0490
2021-02-08 2020-12-31 13F ILLUMINA COM 452327109 83,890 -6,117 -6.80 31,038 11.56 0.0802
2020-12-04 2020-09-30 13F/A-1 ILLUMINA COM 452327109 90,007 -211,778 -70.18 27,821 -75.09 0.0806
2020-11-06 2020-09-30 13F ILLUMINA COM 452327109 91,751 -210,034 28,360 68,284.5745
2020-08-17 2020-06-30 13F/A-1 ILLUMINA COM 452327109 301,785 -26,665 -8.12 111,692 24.54 0.3466
2020-08-11 2020-06-30 13F ILLUMINA COM 452327109 292,950 -35,500 97,392 264,180.9842
2020-05-14 2020-03-31 13F ILLUMINA COM 452327109 328,450 35,246 12.02 89,683 -7.87 0.3294
2020-02-06 2019-12-31 13F ILLUMINA COM 452327109 293,204 46,801 18.99 97,349 29.58 0.2904
2019-11-12 2019-09-30 13F ILLUMINA COM 452327109 246,403 28,562 13.11 75,126 -6.24 0.1922
2019-08-14 2019-06-30 13F ILLUMINA COM 452327109 217,841 31,667 17.01 80,126 38.44 0.2617
2019-05-15 2019-03-31 13F ILLUMINA COM 452327109 186,174 15,971 9.38 57,879 -6.31 0.1944
2019-02-13 2018-12-31 13F ILLUMINA COM 452327109 170,203 1,099 0.65 61,774 -0.41 0.2199
2018-11-08 2018-09-30 13F ILLUMINA COM 452327109 169,104 -6,773 -3.85 62,031 26.28 0.2248
2018-08-03 2018-06-30 13F ILLUMINA COM 452327109 175,877 4,708 2.75 49,121 21.38 0.1670
2018-05-11 2018-03-31 13F ILLUMINA COM 452327109 171,169 -81,805 -32.34 40,468 -26.78 0.1551
2018-02-08 2017-12-31 13F ILLUMINA COM 452327109 252,974 42,132 19.98 55,272 31.60 0.1919
2017-11-06 2017-09-30 13F ILLUMINA COM 452327109 210,842 67,676 47.27 42,000 69.07 0.1493
2017-07-31 2017-06-30 13F ILLUMINA COM 452327109 143,166 70,469 96.94 24,842 100.27 0.0990
2017-05-05 2017-03-31 13F ILLUMINA COM 452327109 72,697 30,390 71.83 12,404 128.98 0.0544
2017-02-02 2016-12-31 13F ILLUMINA COM 452327109 42,307 -21,447 -33.64 5,417 -53.23 0.0262
2016-11-04 2016-09-30 13F ILLUMINA COM 452327109 63,754 -1,476 -2.26 11,581 26.49 0.0588
2016-08-11 2016-06-30 13F ILLUMINA COM 452327109 65,230 -26,398 -28.81 9,156 -38.36 0.0549
2016-05-10 2016-03-31 13F/A-1 ILLUMINA COM 452327109 91,628 -117,155 -56.11 14,854 -62.93 0.0924
2016-02-03 2015-12-31 13F ILLUMINA COM 452327109 208,783 -46,348 -18.17 40,075 -10.66 0.2442
2015-11-02 2015-09-30 13F/A-1 ILLUMINA COM 452327109 255,131 -1,267 -0.49 44,857 -19.88 0.4117
2015-10-30 2015-09-30 13F ILLUMINA COM 452327109 255,131 44,858
2015-08-07 2015-06-30 13F/A-1 IKANG HEALTHCARE GROUP PUT 452327109 0 -243,593 -100.00 0 -100.00
2015-08-07 2015-06-30 13F/A-1 ILLUMINA COM 452327109 256,398 12,805 5.26 55,987 23.81 0.5062
2015-08-04 2015-06-30 13F ILLUMINA COM 452327109 256,398 12,805 55,987 0.5062
2015-05-14 2015-03-31 13F/A-1 ILLUMINA COM 452327109 243,593 14,381 6.27 45,220 6.88 0.3927
2015-05-01 2015-03-31 13F IKANG HEALTHCARE GROUP PUT 452327109 243,593 243,593 45,220 0.3927
2015-02-10 2014-12-31 13F ILLUMINA COM 452327109 229,212 229,212 42,309 0.3740
Disclosed Put Options
File
Date
Effective
Date
Form Security Class ID Opt Avg Share Price Shares ΔShares
(%)
Value
(x1000)
ΔValue
(%)
Prior Allocation
(%)
Allocation
(%)
ΔAllocation
(%)
Cost Basis
(x1000)
Profit
(x1000)
Return
(%)
2015-08-07 2015-06-30 13F/A IKANG HEALTHCARE GROUP PUT 0 -100.00 0 -100.00 n/a n/a n/a
2015-05-01 2015-03-31 13F IKANG HEALTHCARE GROUP PUT 243,593 45,220 n/a n/a n/a
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.