Inspire Medical Systems, Inc.
US ˙ NYSE ˙ US4577301090

SecurityINSP / Inspire Medical Systems, Inc.
InstitutionDeerfield Management Company, L.p. (series C)
Latest Disclosed Ownership2,703,238 shares
Latest Disclosed Value $ 139,433,016
Deerfield Management Company, L.p. (series C) reports 79.51% increase in ownership of INSP / Inspire Medical Systems, Inc.

On May 15, 2026 - Deerfield Management Company, L.p. (series C) filed a 13F-HR form disclosing ownership of 2,703,238 shares of Inspire Medical Systems, Inc. (US:INSP) valued at $139,433,016 USD as of March 31, 2026. The entity filed a previous 13F-HR on February 17, 2026 disclosing 1,505,872 shares of Inspire Medical Systems, Inc.. This represents a change in shares of 79.51% during the quarter. The current value of the position is $109,318,945 USD.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date
Effective
Date
Form Security Class ID Avg Price
Paid (Est)
Reported
Shares
ΔShares ΔShares
(%)
Reported
Value
(x1000)
ΔValue
(%)
Alloc
(%)
ΔAlloc ΔAlloc (%) Cost Basis
(x1000)
Unrealized
Gain/Loss
(x1000)
2026-05-15 2026-03-31 13F INSPIRE MED SYS COM 457730109 2,703,238 1,197,366 79.51 139,433 0.39 1.6450
2026-02-17 2025-12-31 13F INSPIRE MED SYS COM 457730109 1,505,872 458,178 43.73 138,887 78.66 1.7737
2025-11-14 2025-09-30 13F INSPIRE MED SYS COM 457730109 1,047,694 907,694 648.35 77,739 327.91 1.1867
2025-08-14 2025-06-30 13F INSPIRE MED SYS COM 457730109 140,000 140,000 18,168 0.3297
2024-11-14 2024-09-30 13F INSPIRE MED SYS COM 457730109 0 -2,813 -100.00 0 -100.00
2024-08-14 2024-06-30 13F INSPIRE MED SYS COM 457730109 2,813 2,813 376 0.0063
2019-11-14 2019-09-30 13F INSPIRE MED SYS COM 457730109 0 -151,106 -100.00 0 -100.00
2019-08-14 2019-06-30 13F INSPIRE MED SYS COM 457730109 151,106 12,106 8.71 9,165 16.13 0.3292
2019-05-15 2019-03-31 13F INSPIRE MED SYS COM 457730109 139,000 -261,781 -65.32 7,892 -53.39 0.3026
2019-02-14 2018-12-31 13F INSPIRE MED SYS COM 457730109 400,781 211,781 112.05 16,933 112.91 0.6778
2018-11-14 2018-09-30 13F INSPIRE MED SYS COM 457730109 189,000 189,000 7,953 0.2849
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.