Innoviva, Inc.
US ˙ NasdaqGS ˙ US45781M1018

SecurityINVA / Innoviva, Inc.
InstitutionJanus Henderson Group Plc
Latest Disclosed Ownership27,858 shares
Latest Disclosed Value $ 649,091
Janus Henderson Group Plc ownership in INVA / Innoviva, Inc.

On May 18, 2026 - Janus Henderson Group Plc filed a 13F-HR/A form disclosing ownership of 27,858 shares of Innoviva, Inc. (US:INVA) valued at $649,091 USD as of March 31, 2026. The entity filed a previous 13F-HR on February 17, 2026 disclosing 27,858 shares of Innoviva, Inc.. This represents a change in shares of 0.00% during the quarter. The current value of the position is $617,333 USD.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date		 Effective
Date		Form Security Class ID Avg Price
Paid (Est)		 Reported
Shares		 ΔShares ΔShares
(%)		 Reported
Value
(x1000)		 ΔValue
(%)		 Alloc
(%)		 ΔAlloc ΔAlloc (%) Cost Basis
(x1000)		 Unrealized
Gain/Loss
(x1000)
2026-05-18 2026-03-31 13F/A-1 INNOVIVA COM 45781M101 27,858 0 0.00 649 16.52 0.0001
2026-05-15 2026-03-31 13F INNOVIVA COM 45781M101 27,858 0 0.00 649 16.52 0.0001
2026-02-17 2025-12-31 13F INNOVIVA COM 45781M101 27,858 0 0.00 557 9.86 0.0002
2025-11-14 2025-09-30 13F INNOVIVA COM 45781M101 27,858 0 0.00 508 -9.30 0.0002
2025-08-14 2025-06-30 13F INNOVIVA COM 45781M101 27,858 0 0.00 560 10.47 0.0003
2025-05-15 2025-03-31 13F INNOVIVA COM 45781M101 27,858 0 0.00 506 4.76 0.0003
2025-02-14 2024-12-31 13F INNOVIVA COM 45781M101 27,858 0 0.00 484 -10.06 0.0002
2024-11-14 2024-09-30 13F INNOVIVA COM 45781M101 27,858 0 0.00 537 17.76 0.0003
2024-08-14 2024-06-30 13F INNOVIVA COM 45781M101 27,858 -329 -1.17 457 6.29 0.0002
2024-05-15 2024-03-31 13F INNOVIVA COM 45781M101 28,187 3 0.01 429 -4.88 0.0002
2024-02-14 2023-12-31 13F INNOVIVA COM 45781M101 28,184 -55 -0.19 452 23.22 0.0003
2023-11-14 2023-09-30 13F INNOVIVA COM 45781M101 28,239 -605,184 -95.54 367 -93.83 0.0002
2023-08-14 2023-06-30 13F THESEUS PHARMACEUTICALS COM 88369M101 633,423 172,695 37.48 5,929 45.58 0.0037
2023-08-14 2023-06-30 13F INNOVIVA COM 45781M101 28,240 -23 359 0.0002
2023-05-15 2023-03-31 13F THESEUS PHARMACEUTICALS COM 88369M101 460,728 366,727 390.13 4,073 227.07 0.0027
2023-05-15 2023-03-31 13F INNOVIVA COM 45781M101 28,263 -65,738 318 0.0001
2023-02-14 2022-12-31 13F INNOVIVA COM 45781M101 94,001 -6,755 -6.70 1,245 6.32 0.0009
2023-01-13 2022-09-30 13F/A-1 INNOVIVA COM 45781M101 100,756 -578 -0.57 1,171 -21.72 0.0009
2022-11-14 2022-09-30 13F INNOVIVA COM 45781M101 100,756 -578 1,171 0.0003
2022-08-15 2022-06-30 13F INNOVIVA COM 45781M101 101,334 18,013 21.62 1,496 -7.25 0.0010
2022-05-16 2022-03-31 13F INNOVIVA COM 45781M101 83,321 -22,732 -21.43 1,613 -11.86 0.0008
2022-02-14 2021-12-31 13F INNOVIVA COM 45781M101 106,053 9,426 9.76 1,830 13.31 0.0008
2021-11-16 2021-09-30 13F INNOVIVA COM 45781M101 96,627 -69,949 -41.99 1,615 -27.71 0.0007
2021-08-16 2021-06-30 13F INNOVIVA COM 45781M101 166,576 -23,878 -12.54 2,234 -1.85 0.0010
2021-05-17 2021-03-31 13F INNOVIVA COM 45781M101 190,454 47,382 33.12 2,276 28.37 0.0010
2021-02-16 2020-12-31 13F INNOVIVA COM 45781M101 143,072 13,834 10.70 1,773 31.24 0.0008
2020-11-16 2020-09-30 13F INNOVIVA COM 45781M101 129,238 9,522 7.95 1,351 -19.30 0.0007
2020-08-14 2020-06-30 13F INNOVIVA COM 45781M101 119,716 57,648 92.88 1,674 129.32 0.0009
2020-05-14 2020-03-31 13F INNOVIVA COM 45781M101 62,068 3,290 5.60 730 -12.26 0.0005
2020-02-18 2019-12-31 13F INNOVIVA COM 45781M101 58,778 3,040 5.45 832 41.74 0.0004
2019-11-14 2019-09-30 13F INNOVIVA COM 45781M101 55,738 7,520 15.60 587 -16.38 0.0003
2019-07-31 2019-06-30 13F INNOVIVA COM 45781M101 48,218 -1,949 -3.89 702 -0.28 0.0004
2019-04-30 2019-03-31 13F INNOVIVA COM 45781M101 50,167 50,167 704 0.0004
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.