Ionis Pharmaceuticals, Inc.
US ˙ NasdaqGS ˙ US4622221004

SecurityIONS / Ionis Pharmaceuticals, Inc.
InstitutionAmundi
Latest Disclosed Ownership23,958 shares
Latest Disclosed Value $ 1,799,007
Amundi reports 94.80% decrease in ownership of IONS / Ionis Pharmaceuticals, Inc.

On May 15, 2026 - Amundi filed a 13F-HR form disclosing ownership of 23,958 shares of Ionis Pharmaceuticals, Inc. (US:IONS) valued at $1,799,006 USD as of March 31, 2026. The entity filed a previous 13F-HR on February 17, 2026 disclosing 460,947 shares of Ionis Pharmaceuticals, Inc.. This represents a change in shares of -94.80% during the quarter. The current value of the position is $1,768,580 USD.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date
Effective
Date
Form Security Class ID Avg Price
Paid (Est)
Reported
Shares
ΔShares ΔShares
(%)
Reported
Value
(x1000)
ΔValue
(%)
Alloc
(%)
ΔAlloc ΔAlloc (%) Cost Basis
(x1000)
Unrealized
Gain/Loss
(x1000)
2026-05-15 2026-03-31 13F IONIS PHARMACEUTICALS COM 462222100 23,958 -436,989 -94.80 1,799 -95.07 0.0002
2026-02-17 2025-12-31 13F IONIS PHARMACEUTICALS COM 462222100 460,947 359,416 354.00 36,466 420.41 0.0099
2025-11-14 2025-09-30 13F IONIS PHARMACEUTICALS COM 462222100 101,531 101,531 7,008 0.0023
2025-08-13 2025-06-30 13F IONIS PHARMACEUTICALS COM 462222100 0 -3,873 -100.00 0 -100.00
2025-05-15 2025-03-31 13F IONIS PHARMACEUTICALS COM 462222100 3,873 -7,501 -65.95 110 -71.58 0.0000
2025-02-07 2024-12-31 13F IONIS PHARMACEUTICALS COM 462222100 11,374 -116,925 -91.13 388 -92.02 0.0001
2024-11-13 2024-09-30 13F IONIS PHARMACEUTICALS COM 462222100 128,299 -1,176 -0.91 4,850 -17.87 0.0018
2024-08-14 2024-06-30 13F IONIS PHARMACEUTICALS COM 462222100 129,475 -11,301 -8.03 5,904 2.77 0.0023
2024-05-15 2024-03-31 13F IONIS PHARMACEUTICALS COM 462222100 140,776 -131,874 -48.37 5,745 -60.15 0.0025
2024-02-14 2023-12-31 13F IONIS PHARMACEUTICALS COM 462222100 272,650 146,986 116.97 14,418 139.13 0.0065
2023-11-14 2023-09-30 13F IONIS PHARMACEUTICALS COM 462222100 125,664 4,818 3.99 6,029 21.45 0.0030
2023-08-14 2023-06-30 13F IONIS PHARMACEUTICALS COM 462222100 120,846 115,478 2,151.23 4,964 2,432.65 0.0025
2023-05-15 2023-03-31 13F IONIS PHARMACEUTICALS COM 462222100 5,368 1,775 49.40 196 44.12 0.0001
2023-02-14 2022-12-31 13F IONIS PHARMACEUTICALS COM 462222100 3,593 3,593 136 0.0001
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.