Ionis Pharmaceuticals, Inc.
US ˙ NasdaqGS ˙ US4622221004

SecurityIONS / Ionis Pharmaceuticals, Inc.
InstitutionEntropy Technologies, LP
Latest Disclosed Ownership27,207 shares
Latest Disclosed Value $ 2,042,974
Entropy Technologies, LP ownership in IONS / Ionis Pharmaceuticals, Inc.

On May 14, 2026 - Entropy Technologies, LP filed a 13F-HR form disclosing ownership of 27,207 shares of Ionis Pharmaceuticals, Inc. (US:IONS) valued at $2,042,974 USD as of March 31, 2026. The entity filed a previous 13F-HR on February 13, 2026 disclosing 0 shares of Ionis Pharmaceuticals, Inc.. The current value of the position is $2,008,421 USD.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

Upgrade to unlock premium data and export to Excel .

Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date
Effective
Date
Form Security Class ID Avg Price
Paid (Est)
Reported
Shares
ΔShares ΔShares
(%)
Reported
Value
(x1000)
ΔValue
(%)
Alloc
(%)
ΔAlloc ΔAlloc (%) Cost Basis
(x1000)
Unrealized
Gain/Loss
(x1000)
2026-05-14 2026-03-31 13F IONIS PHARMACEUTICALS ORD COM 462222100 27,207 27,207 2,043 0.0942
2026-02-13 2025-12-31 13F IONIS PHARMACEUTICALS ORD COM 462222100 0 -32,925 -100.00 0 -100.00
2025-11-13 2025-09-30 13F IONIS PHARMACEUTICALS ORD COM 462222100 32,925 3,473 11.79 2,154 85.12 0.1611
2025-08-12 2025-06-30 13F IONIS PHARMACEUTICALS COM 462222100 29,452 29,452 1,164 0.0924
2024-08-12 2024-06-30 13F IONIS PHARMACEUTICALS COM 462222100 0 -14,542 -100.00 0 -100.00
2024-05-08 2024-03-31 13F IONIS PHARMACEUTICALS COM 462222100 14,542 14,542 630 0.0672
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.