Iovance Biotherapeutics, Inc.
US ˙ NasdaqGM ˙ US4622601007

SecurityIOVA / Iovance Biotherapeutics, Inc.
InstitutionWolverine Trading, Llc
Latest Disclosed Ownership21,739 shares
Latest Disclosed Value $ 48,478
Wolverine Trading, Llc ownership in IOVA / Iovance Biotherapeutics, Inc.

On November 14, 2025 - Wolverine Trading, Llc filed a 13F-HR form disclosing ownership of 21,739 shares of Iovance Biotherapeutics, Inc. (US:IOVA) valued at $47,174 USD as of September 30, 2025. The entity filed a previous 13F-HR on August 18, 2025 disclosing 0 shares of Iovance Biotherapeutics, Inc.. The current value of the position is $82,391 USD.

Wolverine Trading, Llc has a history of taking positions in derivatives of the underlying security (IOVA) in the form of stock options. The firm currently holds call options representing 210,800 of underlying shares valued at $470,084 USD and put options representing 42,300 of underlying shares valued at $94,329 USD .

Note: prior versions of this page mistakenly stated that the share values represented the number of options, not the number of underlying shares. For more information on the data backing these reports, please see the SEC document Frequently Asked Questions About Form 13F.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Institutional Put/Call Ratios
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In addition to reporting standard equity and debt issues, institutions with more than 100MM assets under management must also disclose their put and call option holdings. Since put options generally indicate negative sentiment, and call options indicate positive sentiment, we can get a sense of the overall institutional sentiment by plotting the ratio of puts to calls. The chart to the right plots the historical put/call ratio for this instrument.

Using Put/Call Ratio as an indicator of investor sentiment overcomes one of the key deficiencies of using total institutional ownership, which is that a significant amount of assets under management are invested passively to track indices. Passively-managed funds do not typically buy options, so the put/call ratio indicator more closely tracks the sentiment of actively-managed funds.

IOVA / Iovance Biotherapeutics, Inc. Historical Put/Call Ratio
Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date
Effective
Date
Form Security Class ID Avg Price
Paid (Est)
Reported
Shares
ΔShares ΔShares
(%)
Reported
Value
(x1000)
ΔValue
(%)
Alloc
(%)
ΔAlloc ΔAlloc (%) Cost Basis
(x1000)
Unrealized
Gain/Loss
(x1000)
2025-11-14 2025-09-30 13F IOVANCE BIOTHERAPEUTICS COM 462260100 21,739 21,739 48 0.0000
2025-08-18 2025-06-30 13F IOVANCE BIOTHERAPEUTICS COM 462260100 0 -28,010 -100.00 0 -100.00
2025-05-15 2025-03-31 13F IOVANCE BIOTHERAPEUTICS COM 462260100 28,010 -13,532 -32.57 100 -66.67 0.0001
2025-02-14 2024-12-31 13F IOVANCE BIOTHERAPEUTICS COM 462260100 41,542 -10,178 -19.68 298 -40.24 0.0003
2024-11-14 2024-09-30 13F IOVANCE BIOTHERAPEUTICS COM 462260100 51,720 17,725 52.14 497 82.72 0.0005
2024-08-14 2024-06-30 13F IOVANCE BIOTHERAPEUTICS COM 462260100 33,995 3,544 11.64 273 -39.69 0.0003
2024-05-15 2024-03-31 13F IOVANCE BIOTHERAPEUTICS COM 462260100 30,451 -91,676 -75.07 451 -54.54 0.0005
2024-02-14 2023-12-31 13F IOVANCE BIOTHERAPEUTICS COM 462260100 122,127 63,265 107.48 993 271.54 0.0010
2023-11-15 2023-09-30 13F IOVANCE BIOTHERAPEUTICS COM 462260100 58,862 2,243 3.96 268 -33.08 0.0003
2023-08-23 2023-06-30 13F IOVANCE BIOTHERAPEUTICS COM 462260100 56,619 23,451 70.70 399 0.0005
2023-05-15 2023-03-31 13F IOVANCE BIOTHERAPEUTICS COM 462260100 33,168 33,168 0 0.0003
2023-02-14 2022-12-31 13F IOVANCE BIOTHERAPEUTICS COM 462260100 0 -16,279 -100.00 0 -100.00
2022-11-14 2022-09-30 13F IOVANCE BIOTHERAPEUTICS COM 462260100 16,279 16,279 155 0.0002
2022-08-15 2022-06-30 13F IOVANCE BIOTHERAPEUTICS COM 462260100 0 -15,912 -100.00 0 -100.00
2022-05-16 2022-03-31 13F IOVANCE BIOTHERAPEUTICS COM 462260100 15,912 -576 -3.49 266 -16.87 0.0003
2022-02-14 2021-12-31 13F IOVANCE BIOTHERAPEUTICS COM 462260100 16,488 -7,771 -32.03 320 -44.54 0.0004
2021-11-12 2021-09-30 13F IOVANCE BIOTHERAPEUTICS COM 462260100 24,259 -4,690 -16.20 577 -24.28 0.0007
2021-08-06 2021-06-30 13F IOVANCE BIOTHERAPEUTICS COM 462260100 28,949 28,677 10,543.01 762 38,000.00 0.0012
2016-08-15 2016-06-30 13F LION BIOTECHNOLOGIES COM 53619R102 272 272 2 0.0000
Disclosed Call Options
File
Date
Effective
Date
Form Security Class ID Opt Avg Share
Price
Shares ΔShares
(%)
Value
(x1000)
ΔValue
(%)
Prior Allocation
(%)
Allocation
(%)
ΔAllocation
(%)
Cost Basis
(x1000)
Profit
(x1000)
Return
(%)
2025-11-14 2025-09-30 13F IOVANCE BIOTHERAPEUTICS COM Call 210,800 470 n/a n/a n/a
2025-08-18 2025-06-30 13F IOVANCE BIOTHERAPEUTICS COM Call 0 -100.00 0 -100.00 n/a n/a n/a
2025-05-15 2025-03-31 13F IOVANCE BIOTHERAPEUTICS COM Call 112,100 70.36 399 -15.29 n/a n/a n/a
2025-02-14 2024-12-31 13F IOVANCE BIOTHERAPEUTICS COM Call 65,800 50.23 472 12.14 n/a n/a n/a
2024-11-14 2024-09-30 13F IOVANCE BIOTHERAPEUTICS COM Call 43,800 -21.08 421 -5.62 n/a n/a n/a
2024-08-14 2024-06-30 13F IOVANCE BIOTHERAPEUTICS COM Call 55,500 -52.77 445 -74.44 n/a n/a n/a
2024-05-15 2024-03-31 13F IOVANCE BIOTHERAPEUTICS COM Call 117,500 -60.17 1,741 -27.40 n/a n/a n/a
2024-02-14 2023-12-31 13F IOVANCE BIOTHERAPEUTICS COM Call 295,000 39.41 2,398 149.27 n/a n/a n/a
2023-11-15 2023-09-30 13F IOVANCE BIOTHERAPEUTICS COM Call 211,600 37.76 963 -11.09 n/a n/a n/a
2023-08-23 2023-06-30 13F IOVANCE BIOTHERAPEUTICS COM Call 153,600 9.32 1,083 n/a n/a n/a
2023-05-15 2023-03-31 13F IOVANCE BIOTHERAPEUTICS COM Call 140,500 106.92 1 -100.00 n/a n/a n/a
2023-02-14 2022-12-31 13F IOVANCE BIOTHERAPEUTICS COM Call 67,900 18.71 434 -20.37 n/a n/a n/a
2022-11-14 2022-09-30 13F IOVANCE BIOTHERAPEUTICS COM Call 57,200 -35.44 545 -43.52 n/a n/a n/a
2022-08-15 2022-06-30 13F IOVANCE BIOTHERAPEUTICS COM Call 88,600 76.85 965 15.29 n/a n/a n/a
2022-05-16 2022-03-31 13F IOVANCE BIOTHERAPEUTICS COM Call 50,100 6.37 837 -8.52 n/a n/a n/a
2022-02-14 2021-12-31 13F IOVANCE BIOTHERAPEUTICS COM Call 47,100 -14.52 915 -30.21 n/a n/a n/a
2021-11-12 2021-09-30 13F IOVANCE BIOTHERAPEUTICS COM Call 55,100 -37.60 1,311 -43.61 n/a n/a n/a
2021-08-06 2021-06-30 13F IOVANCE BIOTHERAPEUTICS COM Call 88,300 2,325 n/a n/a n/a
Disclosed Put Options
File
Date
Effective
Date
Form Security Class ID Opt Avg Share Price Shares ΔShares
(%)
Value
(x1000)
ΔValue
(%)
Prior Allocation
(%)
Allocation
(%)
ΔAllocation
(%)
Cost Basis
(x1000)
Profit
(x1000)
Return
(%)
2025-11-14 2025-09-30 13F IOVANCE BIOTHERAPEUTICS COM Put 42,300 94 n/a n/a n/a
2025-08-18 2025-06-30 13F IOVANCE BIOTHERAPEUTICS COM Put 0 -100.00 0 -100.00 n/a n/a n/a
2025-05-15 2025-03-31 13F IOVANCE BIOTHERAPEUTICS COM Put 25,200 -44.25 90 -72.53 n/a n/a n/a
2025-02-14 2024-12-31 13F IOVANCE BIOTHERAPEUTICS COM Put 45,200 -10.14 324 -32.92 n/a n/a n/a
2024-11-14 2024-09-30 13F IOVANCE BIOTHERAPEUTICS COM Put 50,300 22.68 483 47.26 n/a n/a n/a
2024-08-14 2024-06-30 13F IOVANCE BIOTHERAPEUTICS COM Put 41,000 -38.90 329 -67.00 n/a n/a n/a
2024-05-15 2024-03-31 13F IOVANCE BIOTHERAPEUTICS COM Put 67,100 -17.57 994 50.38 n/a n/a n/a
2024-02-14 2023-12-31 13F IOVANCE BIOTHERAPEUTICS COM Put 81,400 142.99 662 334.87 n/a n/a n/a
2023-11-15 2023-09-30 13F IOVANCE BIOTHERAPEUTICS COM Put 33,500 52.97 152 -1.30 n/a n/a n/a
2023-08-23 2023-06-30 13F IOVANCE BIOTHERAPEUTICS COM Put 21,900 84.03 154 n/a n/a n/a
2023-05-15 2023-03-31 13F IOVANCE BIOTHERAPEUTICS COM Put 11,900 -29.59 0 -100.00 n/a n/a n/a
2023-02-14 2022-12-31 13F IOVANCE BIOTHERAPEUTICS COM Put 16,900 44.44 108 -3.57 n/a n/a n/a
2022-11-14 2022-09-30 13F IOVANCE BIOTHERAPEUTICS COM Put 11,700 -35.00 112 -42.86 n/a n/a n/a
2022-08-15 2022-06-30 13F IOVANCE BIOTHERAPEUTICS COM Put 18,000 -7.69 196 -39.88 n/a n/a n/a
2022-05-16 2022-03-31 13F IOVANCE BIOTHERAPEUTICS COM Put 19,500 13.37 326 -2.40 n/a n/a n/a
2022-02-14 2021-12-31 13F IOVANCE BIOTHERAPEUTICS COM Put 17,200 -10.42 334 -26.91 n/a n/a n/a
2021-11-12 2021-09-30 13F IOVANCE BIOTHERAPEUTICS COM Put 19,200 -47.11 457 -52.20 n/a n/a n/a
2021-08-06 2021-06-30 13F IOVANCE BIOTHERAPEUTICS COM Put 36,300 956 n/a n/a n/a
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.