Krystal Biotech, Inc.
US ˙ NasdaqGS ˙ US5011471027

SecurityKRYS / Krystal Biotech, Inc.
InstitutionWolverine Trading, Llc
Latest Disclosed Ownership2,154 shares
Latest Disclosed Value $ 380,720
Wolverine Trading, Llc ownership in KRYS / Krystal Biotech, Inc.

On November 14, 2025 - Wolverine Trading, Llc filed a 13F-HR form disclosing ownership of 2,154 shares of Krystal Biotech, Inc. (US:KRYS) valued at $380,246 USD as of September 30, 2025. The entity filed a previous 13F-HR on February 14, 2025 disclosing 0 shares of Krystal Biotech, Inc.. The current value of the position is $650,120 USD.

Wolverine Trading, Llc has a history of taking positions in derivatives of the underlying security (KRYS) in the form of stock options. The firm currently holds call options representing 4,400 of underlying shares valued at $777,700 USD and put options representing 16,000 of underlying shares valued at $2,828,000 USD .

Note: prior versions of this page mistakenly stated that the share values represented the number of options, not the number of underlying shares. For more information on the data backing these reports, please see the SEC document Frequently Asked Questions About Form 13F.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Institutional Put/Call Ratios
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In addition to reporting standard equity and debt issues, institutions with more than 100MM assets under management must also disclose their put and call option holdings. Since put options generally indicate negative sentiment, and call options indicate positive sentiment, we can get a sense of the overall institutional sentiment by plotting the ratio of puts to calls. The chart to the right plots the historical put/call ratio for this instrument.

Using Put/Call Ratio as an indicator of investor sentiment overcomes one of the key deficiencies of using total institutional ownership, which is that a significant amount of assets under management are invested passively to track indices. Passively-managed funds do not typically buy options, so the put/call ratio indicator more closely tracks the sentiment of actively-managed funds.

KRYS / Krystal Biotech, Inc. Historical Put/Call Ratio
Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date
Effective
Date
Form Security Class ID Avg Price
Paid (Est)
Reported
Shares
ΔShares ΔShares
(%)
Reported
Value
(x1000)
ΔValue
(%)
Alloc
(%)
ΔAlloc ΔAlloc (%) Cost Basis
(x1000)
Unrealized
Gain/Loss
(x1000)
2025-11-14 2025-09-30 13F KRYSTAL BIOTECH COM 501147102 2,154 2,154 381 0.0003
2025-02-14 2024-12-31 13F KRYSTAL BIOTECH COM 501147102 0 -1,538 -100.00 0 -100.00
2024-11-14 2024-09-30 13F KRYSTAL BIOTECH COM 501147102 1,538 1,538 272 0.0003
2024-02-14 2023-12-31 13F KRYSTAL BIOTECH COM 501147102 0 -2,055 -100.00 0 -100.00
2023-11-15 2023-09-30 13F KRYSTAL BIOTECH COM 501147102 2,055 -333 -13.94 238 -13.77 0.0002
2023-08-23 2023-06-30 13F KRYSTAL BIOTECH COM 501147102 2,388 2,388 276 0.0003
Disclosed Call Options
File
Date
Effective
Date
Form Security Class ID Opt Avg Share
Price
Shares ΔShares
(%)
Value
(x1000)
ΔValue
(%)
Prior Allocation
(%)
Allocation
(%)
ΔAllocation
(%)
Cost Basis
(x1000)
Profit
(x1000)
Return
(%)
2025-11-14 2025-09-30 13F KRYSTAL BIOTECH COM Call 4,400 69.23 778 115.24 n/a n/a n/a
2025-08-18 2025-06-30 13F KRYSTAL BIOTECH COM Call 2,600 -42.22 361 -56.35 n/a n/a n/a
2025-05-15 2025-03-31 13F KRYSTAL BIOTECH COM Call 4,500 32.35 828 52.30 n/a n/a n/a
2025-02-14 2024-12-31 13F KRYSTAL BIOTECH COM Call 3,400 -24.44 543 -31.87 n/a n/a n/a
2024-11-14 2024-09-30 13F KRYSTAL BIOTECH COM Call 4,500 797 n/a n/a n/a
2024-02-14 2023-12-31 13F KRYSTAL BIOTECH COM Call 0 -100.00 0 -100.00 n/a n/a n/a
2023-11-15 2023-09-30 13F KRYSTAL BIOTECH COM Call 2,100 0.00 244 0.41 n/a n/a n/a
2023-08-23 2023-06-30 13F KRYSTAL BIOTECH COM Call 2,100 243 n/a n/a n/a
2021-11-12 2021-09-30 13F KRYSTAL BIOTECH COM Call 0 -100.00 0 -100.00 n/a n/a n/a
2021-08-06 2021-06-30 13F KRYSTAL BIOTECH COM Call 3,100 214 n/a n/a n/a
Disclosed Put Options
File
Date
Effective
Date
Form Security Class ID Opt Avg Share Price Shares ΔShares
(%)
Value
(x1000)
ΔValue
(%)
Prior Allocation
(%)
Allocation
(%)
ΔAllocation
(%)
Cost Basis
(x1000)
Profit
(x1000)
Return
(%)
2025-11-14 2025-09-30 13F KRYSTAL BIOTECH COM Put 16,000 515.38 2,828 683.38 n/a n/a n/a
2025-08-18 2025-06-30 13F KRYSTAL BIOTECH COM Put 2,600 -64.86 361 -73.48 n/a n/a n/a
2025-05-15 2025-03-31 13F KRYSTAL BIOTECH COM Put 7,400 72.09 1,361 98.11 n/a n/a n/a
2025-02-14 2024-12-31 13F KRYSTAL BIOTECH COM Put 4,300 -10.42 687 -19.18 n/a n/a n/a
2024-11-14 2024-09-30 13F KRYSTAL BIOTECH COM Put 4,800 850 n/a n/a n/a
2024-02-14 2023-12-31 13F KRYSTAL BIOTECH COM Put 0 -100.00 0 -100.00 n/a n/a n/a
2023-11-15 2023-09-30 13F KRYSTAL BIOTECH COM Put 2,700 -10.00 313 -9.80 n/a n/a n/a
2023-08-23 2023-06-30 13F KRYSTAL BIOTECH COM Put 3,000 347 n/a n/a n/a
2023-05-15 2023-03-31 13F KRYSTAL BIOTECH COM Put 0 -100.00 0 -100.00 n/a n/a n/a
2023-02-14 2022-12-31 13F KRYSTAL BIOTECH COM Put 4,200 333 n/a n/a n/a
2021-11-12 2021-09-30 13F KRYSTAL BIOTECH COM Put 0 -100.00 0 -100.00 n/a n/a n/a
2021-08-06 2021-06-30 13F KRYSTAL BIOTECH COM Put 3,000 207 n/a n/a n/a
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.