Madrigal Pharmaceuticals, Inc.
US ˙ NasdaqGS ˙ US5588681057

SecurityMDGL / Madrigal Pharmaceuticals, Inc.
InstitutionWolverine Trading, Llc
Latest Disclosed Ownership5,056 shares
Latest Disclosed Value $ 2,240,314
Wolverine Trading, Llc ownership in MDGL / Madrigal Pharmaceuticals, Inc.

On November 14, 2025 - Wolverine Trading, Llc filed a 13F-HR form disclosing ownership of 5,056 shares of Madrigal Pharmaceuticals, Inc. (US:MDGL) valued at $2,318,985 USD as of September 30, 2025. The entity filed a previous 13F-HR on August 18, 2025 disclosing 972 shares of Madrigal Pharmaceuticals, Inc.. This represents a change in shares of 420.16% during the quarter. The current value of the position is $2,468,086 USD.

Wolverine Trading, Llc has a history of taking positions in derivatives of the underlying security (MDGL) in the form of stock options. The firm currently holds call options representing 19,200 of underlying shares valued at $8,507,520 USD and put options representing 7,500 of underlying shares valued at $3,323,250 USD .

Note: prior versions of this page mistakenly stated that the share values represented the number of options, not the number of underlying shares. For more information on the data backing these reports, please see the SEC document Frequently Asked Questions About Form 13F.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Institutional Put/Call Ratios
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In addition to reporting standard equity and debt issues, institutions with more than 100MM assets under management must also disclose their put and call option holdings. Since put options generally indicate negative sentiment, and call options indicate positive sentiment, we can get a sense of the overall institutional sentiment by plotting the ratio of puts to calls. The chart to the right plots the historical put/call ratio for this instrument.

Using Put/Call Ratio as an indicator of investor sentiment overcomes one of the key deficiencies of using total institutional ownership, which is that a significant amount of assets under management are invested passively to track indices. Passively-managed funds do not typically buy options, so the put/call ratio indicator more closely tracks the sentiment of actively-managed funds.

MDGL / Madrigal Pharmaceuticals, Inc. Historical Put/Call Ratio
Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date
Effective
Date
Form Security Class ID Avg Price
Paid (Est)
Reported
Shares
ΔShares ΔShares
(%)
Reported
Value
(x1000)
ΔValue
(%)
Alloc
(%)
ΔAlloc ΔAlloc (%) Cost Basis
(x1000)
Unrealized
Gain/Loss
(x1000)
2025-11-14 2025-09-30 13F MADRIGAL PHARMACEUTICALS COM 558868105 5,056 4,084 420.16 2,240 667.12 0.0016
2025-08-18 2025-06-30 13F MADRIGAL PHARMACEUTICALS COM 558868105 972 307 46.17 292 33.94 0.0003
2025-05-15 2025-03-31 13F MADRIGAL PHARMACEUTICALS COM 558868105 665 -5,254 -88.76 218 -88.18 0.0003
2025-02-14 2024-12-31 13F MADRIGAL PHARMACEUTICALS COM 558868105 5,919 920 18.40 1,844 73.80 0.0017
2024-11-14 2024-09-30 13F MADRIGAL PHARMACEUTICALS COM 558868105 4,999 417 9.10 1,062 -17.30 0.0011
2024-08-14 2024-06-30 13F MADRIGAL PHARMACEUTICALS COM 558868105 4,582 4,582 1,284 0.0014
2024-05-15 2024-03-31 13F MADRIGAL PHARMACEUTICALS COM 558868105 0 -4,503 -100.00 0 -100.00
2024-02-14 2023-12-31 13F MADRIGAL PHARMACEUTICALS COM 558868105 4,503 286 6.78 1,042 69.27 0.0011
2023-11-15 2023-09-30 13F MADRIGAL PHARMACEUTICALS COM 558868105 4,217 -5,566 -56.89 616 -71.45 0.0006
2023-08-23 2023-06-30 13F MADRIGAL PHARMACEUTICALS COM 558868105 9,783 4,393 81.50 2,154 215,300.00 0.0026
2023-05-15 2023-03-31 13F MADRIGAL PHARMACEUTICALS COM 558868105 5,390 5,390 1 0.0020
2022-11-14 2022-09-30 13F MADRIGAL PHARMACEUTICALS COM 558868105 0 -6,565 -100.00 0 -100.00
2022-08-15 2022-06-30 13F MADRIGAL PHARMACEUTICALS COM 558868105 6,565 4,071 163.23 472 90.32 0.0008
2022-05-16 2022-03-31 13F MADRIGAL PHARMACEUTICALS COM 558868105 2,494 -8,674 -77.67 248 -73.84 0.0003
2022-02-14 2021-12-31 13F MADRIGAL PHARMACEUTICALS COM 558868105 11,168 6,868 159.72 948 175.58 0.0011
2021-11-12 2021-09-30 13F MADRIGAL PHARMACEUTICALS COM 558868105 4,300 1,860 76.23 344 45.15 0.0004
2021-08-06 2021-06-30 13F MADRIGAL PHARMACEUTICALS COM 558868105 2,440 269 12.39 237 -6.32 0.0004
2021-05-14 2021-03-31 13F MADRIGAL PHARMACEUTICALS COM 558868105 2,171 2,171 253 0.0004
2020-11-13 2020-09-30 13F MADRIGAL PHARMACEUTICALS COM 558868105 0 -2,075 -100.00 0 -100.00
2020-08-13 2020-06-30 13F MADRIGAL PHARMACEUTICALS COM 558868105 2,075 2,075 213 0.0006
Disclosed Call Options
File
Date
Effective
Date
Form Security Class ID Opt Avg Share
Price
Shares ΔShares
(%)
Value
(x1000)
ΔValue
(%)
Prior Allocation
(%)
Allocation
(%)
ΔAllocation
(%)
Cost Basis
(x1000)
Profit
(x1000)
Return
(%)
2025-11-14 2025-09-30 13F MADRIGAL PHARMACEUTICALS COM Call 19,200 22.29 8,508 80.19 n/a n/a n/a
2025-08-18 2025-06-30 13F MADRIGAL PHARMACEUTICALS COM Call 15,700 -32.03 4,722 -37.66 n/a n/a n/a
2025-05-15 2025-03-31 13F MADRIGAL PHARMACEUTICALS COM Call 23,100 30.51 7,574 37.32 n/a n/a n/a
2025-02-14 2024-12-31 13F MADRIGAL PHARMACEUTICALS COM Call 17,700 80.61 5,516 165.02 n/a n/a n/a
2024-11-14 2024-09-30 13F MADRIGAL PHARMACEUTICALS COM Call 9,800 -14.78 2,082 -35.39 n/a n/a n/a
2024-08-14 2024-06-30 13F MADRIGAL PHARMACEUTICALS COM Call 11,500 -70.74 3,222 -69.31 n/a n/a n/a
2024-05-15 2024-03-31 13F MADRIGAL PHARMACEUTICALS COM Call 39,300 51.15 10,495 74.46 n/a n/a n/a
2024-02-14 2023-12-31 13F MADRIGAL PHARMACEUTICALS COM Call 26,000 68.83 6,016 167.45 n/a n/a n/a
2023-11-15 2023-09-30 13F MADRIGAL PHARMACEUTICALS COM Call 15,400 -9.41 2,249 -39.91 n/a n/a n/a
2023-08-23 2023-06-30 13F MADRIGAL PHARMACEUTICALS COM Call 17,000 22.30 3,744 124,666.67 n/a n/a n/a
2023-05-15 2023-03-31 13F MADRIGAL PHARMACEUTICALS COM Call 13,900 3 n/a n/a n/a
2023-02-14 2022-12-31 13F MADRIGAL PHARMACEUTICALS COM Call 0 -100.00 0 -100.00 n/a n/a n/a
2022-11-14 2022-09-30 13F MADRIGAL PHARMACEUTICALS COM Call 14,500 215.22 912 175.53 n/a n/a n/a
2022-08-15 2022-06-30 13F MADRIGAL PHARMACEUTICALS COM Call 4,600 -9.80 331 -34.71 n/a n/a n/a
2022-05-16 2022-03-31 13F MADRIGAL PHARMACEUTICALS COM Call 5,100 -60.77 507 -54.08 n/a n/a n/a
2022-02-14 2021-12-31 13F MADRIGAL PHARMACEUTICALS COM Call 13,000 13.04 1,104 20.00 n/a n/a n/a
2021-11-12 2021-09-30 13F MADRIGAL PHARMACEUTICALS COM Call 11,500 134.69 920 93.28 n/a n/a n/a
2021-08-06 2021-06-30 13F MADRIGAL PHARMACEUTICALS COM Call 4,900 -37.97 476 -48.26 n/a n/a n/a
2021-05-14 2021-03-31 13F MADRIGAL PHARMACEUTICALS COM Call 7,900 -22.55 920 -18.80 n/a n/a n/a
2021-02-12 2020-12-31 13F MADRIGAL PHARMACEUTICALS COM Call 10,200 -47.96 1,133 -51.52 n/a n/a n/a
2020-11-13 2020-09-30 13F MADRIGAL PHARMACEUTICALS COM Call 19,600 47.37 2,337 71.08 n/a n/a n/a
2020-08-13 2020-06-30 13F MADRIGAL PHARMACEUTICALS COM Call 13,300 303.03 1,366 491.34 n/a n/a n/a
2020-05-11 2020-03-31 13F MADRIGAL PHARMACEUTICALS COM Call 3,300 231 n/a n/a n/a
Disclosed Put Options
File
Date
Effective
Date
Form Security Class ID Opt Avg Share Price Shares ΔShares
(%)
Value
(x1000)
ΔValue
(%)
Prior Allocation
(%)
Allocation
(%)
ΔAllocation
(%)
Cost Basis
(x1000)
Profit
(x1000)
Return
(%)
2025-11-14 2025-09-30 13F MADRIGAL PHARMACEUTICALS COM Put 7,500 240.91 3,323 402.72 n/a n/a n/a
2025-08-18 2025-06-30 13F MADRIGAL PHARMACEUTICALS COM Put 2,200 -56.00 662 -59.67 n/a n/a n/a
2025-05-15 2025-03-31 13F MADRIGAL PHARMACEUTICALS COM Put 5,000 -65.28 1,639 -63.47 n/a n/a n/a
2025-02-14 2024-12-31 13F MADRIGAL PHARMACEUTICALS COM Put 14,400 18.03 4,487 73.18 n/a n/a n/a
2024-11-14 2024-09-30 13F MADRIGAL PHARMACEUTICALS COM Put 12,200 -20.78 2,592 -39.94 n/a n/a n/a
2024-08-14 2024-06-30 13F MADRIGAL PHARMACEUTICALS COM Put 15,400 -39.84 4,314 -36.89 n/a n/a n/a
2024-05-15 2024-03-31 13F MADRIGAL PHARMACEUTICALS COM Put 25,600 319.67 6,836 384.48 n/a n/a n/a
2024-02-14 2023-12-31 13F MADRIGAL PHARMACEUTICALS COM Put 6,100 -18.67 1,411 28.86 n/a n/a n/a
2023-11-15 2023-09-30 13F MADRIGAL PHARMACEUTICALS COM Put 7,500 -43.61 1,095 -62.60 n/a n/a n/a
2023-08-23 2023-06-30 13F MADRIGAL PHARMACEUTICALS COM Put 13,300 46.15 2,929 146,300.00 n/a n/a n/a
2023-05-15 2023-03-31 13F MADRIGAL PHARMACEUTICALS COM Put 9,100 2 n/a n/a n/a
2023-02-14 2022-12-31 13F MADRIGAL PHARMACEUTICALS COM Put 0 -100.00 0 -100.00 n/a n/a n/a
2022-11-14 2022-09-30 13F MADRIGAL PHARMACEUTICALS COM Put 9,300 -16.22 585 -26.78 n/a n/a n/a
2022-08-15 2022-06-30 13F MADRIGAL PHARMACEUTICALS COM Put 11,100 799 n/a n/a n/a
2022-05-16 2022-03-31 13F MADRIGAL PHARMACEUTICALS COM Put 0 -100.00 0 -100.00 n/a n/a n/a
2022-02-14 2021-12-31 13F MADRIGAL PHARMACEUTICALS COM Put 8,400 -2.33 713 3.63 n/a n/a n/a
2021-11-12 2021-09-30 13F MADRIGAL PHARMACEUTICALS COM Put 8,600 688 n/a n/a n/a
2021-08-06 2021-06-30 13F MADRIGAL PHARMACEUTICALS COM Put 0 -100.00 0 -100.00 n/a n/a n/a
2021-05-14 2021-03-31 13F MADRIGAL PHARMACEUTICALS COM Put 3,700 -9.76 431 -5.48 n/a n/a n/a
2021-02-12 2020-12-31 13F MADRIGAL PHARMACEUTICALS COM Put 4,100 0.00 456 -6.75 n/a n/a n/a
2020-11-13 2020-09-30 13F MADRIGAL PHARMACEUTICALS COM Put 4,100 489 n/a n/a n/a
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.