Medpace Holdings, Inc.
US ˙ NasdaqGS ˙ US58506Q1094

SecurityMEDP / Medpace Holdings, Inc.
InstitutionD. E. Shaw & Co., Inc.
ManagerDE Shaw
Latest Disclosed Ownership432,602 shares
Latest Disclosed Value $ 207,731,154
D. E. Shaw & Co., Inc. reports 18.10% decrease in ownership of MEDP / Medpace Holdings, Inc.

On May 15, 2026 - D. E. Shaw & Co., Inc. filed a 13F-HR form disclosing ownership of 432,602 shares of Medpace Holdings, Inc. (US:MEDP) valued at $207,731,154 USD as of March 31, 2026. The entity filed a previous 13F-HR on February 17, 2026 disclosing 528,232 shares of Medpace Holdings, Inc.. This represents a change in shares of -18.10% during the quarter. The current value of the position is $195,023,471 USD.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date		 Effective
Date		Form Security Class ID Avg Price
Paid (Est)		 Reported
Shares		 ΔShares ΔShares
(%)		 Reported
Value
(x1000)		 ΔValue
(%)		 Alloc
(%)		 ΔAlloc ΔAlloc (%) Cost Basis
(x1000)		 Unrealized
Gain/Loss
(x1000)
2026-05-15 2026-03-31 13F MEDPACE HLDGS COM 58506Q109 432,602 -95,630 -18.10 207,731 -29.98 0.1249
2026-02-17 2025-12-31 13F MEDPACE HLDGS COM 58506Q109 528,232 -71,908 -11.98 296,682 -3.85 0.1626
2025-11-14 2025-09-30 13F MEDPACE HLDGS COM 58506Q109 600,140 256,577 74.68 308,568 186.16 0.1742
2025-08-14 2025-06-30 13F MEDPACE HLDGS COM 58506Q109 343,563 129,385 60.41 107,831 65.24 0.0764
2025-05-15 2025-03-31 13F MEDPACE HLDGS COM 58506Q109 214,178 35,898 20.14 65,258 10.18 0.0581
2025-02-14 2024-12-31 13F MEDPACE HLDGS COM 58506Q109 178,280 -30,261 -14.51 59,230 -14.91 0.0435
2024-11-14 2024-09-30 13F MEDPACE HLDGS COM 58506Q109 208,541 -91,324 -30.46 69,611 -43.64 0.0598
2024-08-14 2024-06-30 13F MEDPACE HLDGS COM 58506Q109 299,865 -72,214 -19.41 123,499 -17.87 0.1155
2024-05-15 2024-03-31 13F MEDPACE HLDGS COM 58506Q109 372,079 140,519 60.68 150,376 111.86 0.1287
2024-02-14 2023-12-31 13F MEDPACE HLDGS COM 58506Q109 231,560 87,240 60.45 70,980 103.13 0.0620
2023-11-14 2023-09-30 13F MEDPACE HLDGS COM 58506Q109 144,320 -114,693 -44.28 34,944 -43.83 0.0365
2023-08-14 2023-06-30 13F MEDPACE HLDGS COM 58506Q109 259,013 108,623 72.23 62,207 119.97 0.0635
2023-05-15 2023-03-31 13F MEDPACE HLDGS COM 58506Q109 150,390 7,861 5.52 28,281 -6.59 0.0303
2023-02-14 2022-12-31 13F MEDPACE HLDGS COM 58506Q109 142,529 98,200 221.53 30,275 334.53 0.0335
2022-11-14 2022-09-30 13F MEDPACE HLDGS COM 58506Q109 44,329 -1,714 -3.72 6,967 1.09 0.0083
2022-08-15 2022-06-30 13F MEDPACE HLDGS COM 58506Q109 46,043 22,272 93.69 6,892 77.22 0.0081
2022-05-16 2022-03-31 13F MEDPACE HLDGS COM 58506Q109 23,771 12,346 108.06 3,889 56.44 0.0036
2022-02-14 2021-12-31 13F MEDPACE HLDGS COM 58506Q109 11,425 3,698 47.86 2,486 70.04 0.0021
2021-11-15 2021-09-30 13F MEDPACE HLDGS COM 58506Q109 7,727 -9,462 -55.05 1,462 -51.84 0.0013
2021-08-16 2021-06-30 13F MEDPACE HLDGS COM 58506Q109 17,189 -17,112 -49.89 3,036 -46.05 0.0026
2021-05-17 2021-03-31 13F MEDPACE HLDGS COM 58506Q109 34,301 -50,253 -59.43 5,627 -52.19 0.0054
2021-02-16 2020-12-31 13F MEDPACE HLDGS COM 58506Q109 84,554 -184,076 -68.52 11,770 -60.79 0.0105
2020-11-16 2020-09-30 13F MEDPACE HLDGS COM 58506Q109 268,630 41,310 18.17 30,020 41.97 0.0307
2020-08-14 2020-06-30 13F MEDPACE HLDGS COM 58506Q109 227,320 -50,452 -18.16 21,145 3.74 0.0252
2020-05-15 2020-03-31 13F MEDPACE HLDGS COM 58506Q109 277,772 91,079 48.79 20,383 29.89 0.0318
2020-02-14 2019-12-31 13F MEDPACE HLDGS COM 58506Q109 186,693 -104,933 -35.98 15,693 -35.97 0.0179
2019-11-14 2019-09-30 13F MEDPACE HLDGS COM 58506Q109 291,626 120,688 70.60 24,508 119.15 0.0302
2019-08-14 2019-06-30 13F MEDPACE HLDGS COM 58506Q109 170,938 -43,234 -20.19 11,183 -11.46 0.0139
2019-05-15 2019-03-31 13F MEDPACE HLDGS COM 58506Q109 214,172 -85,293 -28.48 12,630 -20.32 0.0163
2019-02-14 2018-12-31 13F MEDPACE HLDGS COM 58506Q109 299,465 -241,334 -44.63 15,851 -51.08 0.0218
2018-11-14 2018-09-30 13F MEDPACE HLDGS COM 58506Q109 540,799 436,834 420.17 32,399 624.65 0.0389
2018-08-14 2018-06-30 13F MEDPACE HLDGS COM 58506Q109 103,965 -7,209 -6.48 4,471 15.20 0.0058
2018-05-15 2018-03-31 13F MEDPACE HLDGS COM 58506Q109 111,174 -55,859 -33.44 3,881 -35.93 0.0053
2018-02-14 2017-12-31 13F MEDPACE HLDGS COM 58506Q109 167,033 101,341 154.27 6,057 188.98 0.0083
2017-11-14 2017-09-30 13F MEDPACE HLDGS COM 58506Q109 65,692 -8,266 -11.18 2,096 -2.28 0.0032
2017-08-14 2017-06-30 13F MEDPACE HLDGS COM 58506Q109 73,958 73,958 2,145 0.0035
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.