Nuvation Bio Inc.
US ˙ NYSE ˙ US67080N1019

SecurityNUVB / Nuvation Bio Inc.
InstitutionD. E. Shaw & Co., Inc.
ManagerDE Shaw
Latest Disclosed Ownership392,986 shares
Latest Disclosed Value $ 1,685,910
D. E. Shaw & Co., Inc. reports 55.13% decrease in ownership of NUVB / Nuvation Bio Inc.

On May 15, 2026 - D. E. Shaw & Co., Inc. filed a 13F-HR form disclosing ownership of 392,986 shares of Nuvation Bio Inc. (US:NUVB) valued at $1,685,910 USD as of March 31, 2026. The entity filed a previous 13F-HR on February 17, 2026 disclosing 875,802 shares of Nuvation Bio Inc.. This represents a change in shares of -55.13% during the quarter. The current value of the position is $1,854,894 USD.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date
Effective
Date
Form Security Class ID Avg Price
Paid (Est)
Reported
Shares
ΔShares ΔShares
(%)
Reported
Value
(x1000)
ΔValue
(%)
Alloc
(%)
ΔAlloc ΔAlloc (%) Cost Basis
(x1000)
Unrealized
Gain/Loss
(x1000)
2026-05-15 2026-03-31 13F NUVATION BIO COM CL A 67080N101 392,986 -482,816 -55.13 1,686 -78.53 0.0010
2026-02-17 2025-12-31 13F NUVATION BIO COM CL A 67080N101 875,802 875,802 7,847 0.0043
2025-08-14 2025-06-30 13F NUVATION BIO COM CL A 67080N101 0 -12,100 -100.00 0 -100.00
2025-05-15 2025-03-31 13F NUVATION BIO COM CL A 67080N101 12,100 -35,300 -74.47 21 -83.33 0.0000
2025-02-14 2024-12-31 13F NUVATION BIO COM CL A 67080N101 47,400 -63,827 -57.38 126 -50.39 0.0001
2024-11-14 2024-09-30 13F NUVATION BIO COM CL A 67080N101 111,227 -60,568 -35.26 255 -49.30 0.0002
2024-08-14 2024-06-30 13F NUVATION BIO COM CL A 67080N101 171,795 -689,145 -80.05 502 -84.01 0.0005
2024-05-15 2024-03-31 13F NUVATION BIO COM CL A 67080N101 860,940 346,010 67.20 3,134 303.22 0.0027
2024-02-14 2023-12-31 13F NUVATION BIO COM CL A 67080N101 514,930 446,959 657.57 778 753.85 0.0007
2023-11-14 2023-09-30 13F NUVATION BIO COM CL A 67080N101 67,971 -44,265 -39.44 91 -54.95 0.0001
2023-08-14 2023-06-30 13F NUVATION BIO COM CL A 67080N101 112,236 32,535 40.82 202 53.03 0.0002
2023-05-15 2023-03-31 13F NUVATION BIO COM CL A 67080N101 79,701 -38,570 -32.61 132 -41.85 0.0001
2023-02-14 2022-12-31 13F NUVATION BIO COM CL A 67080N101 118,271 -100,554 -45.95 227 -53.67 0.0003
2022-11-14 2022-09-30 13F NUVATION BIO COM CL A 67080N101 218,825 71,110 48.14 490 2.30 0.0006
2022-08-15 2022-06-30 13F NUVATION BIO COM CL A 67080N101 147,715 114,937 350.65 479 178.49 0.0006
2022-05-16 2022-03-31 13F NUVATION BIO COM CL A 67080N101 32,778 -37,192 -53.15 172 -71.09 0.0002
2022-02-14 2021-12-31 13F NUVATION BIO COM CL A 67080N101 69,970 -95,521 -57.72 595 -63.83 0.0005
2021-11-15 2021-09-30 13F NUVATION BIO COM CL A 67080N101 165,491 -3,424 -2.03 1,645 4.58 0.0015
2021-08-16 2021-06-30 13F NUVATION BIO COM CL A 67080N101 168,915 168,915 1,573 0.0014
2021-05-17 2021-03-31 13F PANACEA ACQUISITION UNIT 99/99/9999 698102209 0 -106,200 -100.00 0 -100.00
2021-02-16 2020-12-31 13F PANACEA ACQUISITION UNIT 99/99/9999 698102209 106,200 106,200 1,355 0.0012
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.