OptimizeRx Corporation
US ˙ NasdaqCM ˙ US68401U2042

SecurityOPRX / OptimizeRx Corporation
InstitutionSei Investments Co
Latest Disclosed Ownership53,789 shares
Latest Disclosed Value $ 659,453
Sei Investments Co ownership in OPRX / OptimizeRx Corporation

On February 13, 2026 - Sei Investments Co filed a 13F-HR form disclosing ownership of 53,789 shares of OptimizeRx Corporation (US:OPRX) valued at $659,453 USD as of December 31, 2025. The entity filed a previous 13F-HR on November 14, 2022 disclosing 0 shares of OptimizeRx Corporation. The current value of the position is $266,256 USD.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date
Effective
Date
Form Security Class ID Avg Price
Paid (Est)
Reported
Shares
ΔShares ΔShares
(%)
Reported
Value
(x1000)
ΔValue
(%)
Alloc
(%)
ΔAlloc ΔAlloc (%) Cost Basis
(x1000)
Unrealized
Gain/Loss
(x1000)
2026-02-13 2025-12-31 13F OPTIMIZERX COM NEW 68401U204 53,789 53,789 659
2022-11-14 2022-09-30 13F OPTIMIZERX COM NEW 68401U204 0 -29,154 -100.00 0 -100.00
2022-08-15 2022-06-30 13F OPTIMIZERX COM NEW 68401U204 29,154 13,124 81.87 799 32.28 0.0017
2022-05-13 2022-03-31 13F OPTIMIZERX COM NEW 68401U204 16,030 -6,345 -28.36 604 -56.55 0.0012
2022-02-14 2021-12-31 13F OPTIMIZERX COM NEW 68401U204 22,375 -21,529 -49.04 1,390 -62.99 0.0026
2021-11-12 2021-09-30 13F OPTIMIZERX COM NEW 68401U204 43,904 11,224 34.35 3,756 85.66 0.0079
2021-08-06 2021-06-30 13F OPTIMIZERX COM NEW 68401U204 32,680 2,875 9.65 2,023 44.09 0.0045
2021-05-12 2021-03-31 13F OPTIMIZERX COM NEW 68401U204 29,805 29,805 1,404 0.0035
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.