Pacific Biosciences of California, Inc.
US ˙ NasdaqGS ˙ US69404D1081

SecurityPACB / Pacific Biosciences of California, Inc.
InstitutionNorthern Trust Corp
Latest Disclosed Ownership2,130,788 shares
Latest Disclosed Value $ 2,812,640
Northern Trust Corp reports 4.10% increase in ownership of PACB / Pacific Biosciences of California, Inc.

On May 14, 2026 - Northern Trust Corp filed a 13F-HR form disclosing ownership of 2,130,788 shares of Pacific Biosciences of California, Inc. (US:PACB) valued at $2,812,640 USD as of March 31, 2026. The entity filed a previous 13F-HR on February 17, 2026 disclosing 2,046,839 shares of Pacific Biosciences of California, Inc.. This represents a change in shares of 4.10% during the quarter. The current value of the position is $3,473,184 USD.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date		 Effective
Date		Form Security Class ID Avg Price
Paid (Est)		 Reported
Shares		 ΔShares ΔShares
(%)		 Reported
Value
(x1000)		 ΔValue
(%)		 Alloc
(%)		 ΔAlloc ΔAlloc (%) Cost Basis
(x1000)		 Unrealized
Gain/Loss
(x1000)
2026-05-14 2026-03-31 13F PACIFIC BIOSCIENCES CALIF IN COM 69404D108 2,130,788 83,949 4.10 2,813 -26.52 0.0001
2026-02-17 2025-12-31 13F PACIFIC BIOSCIENCES CALIF IN COM 69404D108 2,046,839 -242,057 -10.58 3,828 30.66 0.0005
2025-11-14 2025-09-30 13F PACIFIC BIOSCIENCES CALIF IN COM 69404D108 2,288,896 82,803 3.75 2,930 7.09 0.0004
2025-08-13 2025-06-30 13F PACIFIC BIOSCIENCES CALIF IN COM 69404D108 2,206,093 -228,596 -9.39 2,736 -4.77 0.0004
2025-05-13 2025-03-31 13F PACIFIC BIOSCIENCES CALIF IN COM 69404D108 2,434,689 -80,135 -3.19 2,873 -37.59 0.0004
2025-02-14 2024-12-31 13F PACIFIC BIOSCIENCES CALIF IN COM 69404D108 2,514,824 157,145 6.67 4,602 14.82 0.0007
2024-11-13 2024-09-30 13F PACIFIC BIOSCIENCES CALIF IN COM 69404D108 2,357,679 -146,597 -5.85 4,008 16.85 0.0007
2024-08-14 2024-06-30 13F PACIFIC BIOSCIENCES CALIF IN COM 69404D108 2,504,276 -38,621 -1.52 3,431 -64.03 0.0006
2024-05-14 2024-03-31 13F PACIFIC BIOSCIENCES CALIF IN COM 69404D108 2,542,897 -154,796 -5.74 9,536 -63.97 0.0016
2024-02-13 2023-12-31 13F PACIFIC BIOSCIENCES CALIF IN COM 69404D108 2,697,693 -121,072 -4.30 26,464 12.44 0.0048
2023-11-13 2023-09-30 13F PACIFIC BIOSCIENCES CALIF IN COM 69404D108 2,818,765 3,004 0.11 23,537 -37.15 0.0046
2023-08-11 2023-06-30 13F PACIFIC BIOSCIENCES CALIF IN COM 69404D108 2,815,761 276,619 10.89 37,450 27.36 0.0072
2023-05-15 2023-03-31 13F PACIFIC BIOSCIENCES CALIF IN COM 69404D108 2,539,142 140,999 5.88 29,403 49.89 0.0058
2023-02-13 2022-12-31 13F PACIFIC BIOSCIENCES CALIF IN COM 69404D108 2,398,143 -15,933 -0.66 19,617 39.98 0.0041
2022-11-14 2022-09-30 13F PACIFIC BIOSCIENCES CALIF IN COM 69404D108 2,414,076 294,991 13.92 14,013 49.62 0.0032
2022-08-12 2022-06-30 13F PACIFIC BIOSCIENCES CALIF IN COM 69404D108 2,119,085 139,317 7.04 9,366 -48.01 0.0020
2022-05-13 2022-03-31 13F PACIFIC BIOSCIENCES CALIF IN COM 69404D108 1,979,768 -4,190 -0.21 18,016 -55.62 0.0032
2022-02-08 2021-12-31 13F PACIFIC BIOSCIENCES CALIF IN COM 69404D108 1,983,958 -318,587 -13.84 40,592 -31.00 0.0066
2021-11-15 2021-09-30 13F PACIFIC BIOSCIENCES CALIF IN COM 69404D108 2,302,545 -44,413 -1.89 58,830 -28.32 0.0104
2021-08-13 2021-06-30 13F PACIFIC BIOSCIENCES CALIF IN COM 69404D108 2,346,958 278,659 13.47 82,074 19.13 0.0145
2021-05-12 2021-03-31 13F PACIFIC BIOSCIENCES CALIF IN COM 69404D108 2,068,299 -55,839 -2.63 68,894 25.03 0.0128
2021-02-11 2020-12-31 13F PACIFIC BIOSCIENCES CALIF IN COM 69404D108 2,124,138 49,337 2.38 55,100 169.06 0.0107
2020-11-16 2020-09-30 13F PACIFIC BIOSCIENCES CALIF IN COM 69404D108 2,074,801 164,625 8.62 20,479 210.81 0.0045
2020-08-14 2020-06-30 13F PACIFIC BIOSCIENCES CALIF IN COM 69404D108 1,910,176 108,371 6.01 6,589 19.52 0.0016
2020-05-14 2020-03-31 13F PACIFIC BIOSCIENCES CALIF IN COM 69404D108 1,801,805 27,194 1.53 5,513 -39.56 0.0016
2020-02-14 2019-12-31 13F PACIFIC BIOSCIENCES CALIF IN COM 69404D108 1,774,611 -56,013 -3.06 9,122 -3.43 0.0020
2019-11-13 2019-09-30 13F PACIFIC BIOSCIENCES CALIF IN COM 69404D108 1,830,624 74,029 4.21 9,446 -11.11 0.0023
2019-08-13 2019-06-30 13F PACIFIC BIOSCIENCES CALIF IN COM 69404D108 1,756,595 13,290 0.76 10,627 -15.69 0.0025
2019-05-13 2019-03-31 13F PACIFIC BIOSCIENCES CALIF IN COM 69404D108 1,743,305 55,777 3.31 12,604 0.93 0.0031
2019-02-12 2018-12-31 13F PACIFIC BIOSCIENCES CALIF IN COM 69404D108 1,687,528 161,208 10.56 12,488 51.22 0.0035
2018-11-14 2018-09-30 13F PACIFIC BIOSCIENCES CALIF IN COM 69404D108 1,526,320 63,090 4.31 8,258 58.96 0.0020
2018-09-18 2018-06-30 13F/A-1 PACIFIC BIOSCIENCES CALIF IN COM 69404D108 1,463,230 140,090 10.59 5,195 91.49 0.0013
2018-08-14 2018-06-30 13F PACIFIC BIOSCIENCES CALIF IN COM 69404D108 1,471,323 148,183 5,223
2018-05-09 2018-03-31 13F PACIFIC BIOSCIENCES CALIF IN COM 69404D108 1,323,140 118,214 9.81 2,713 -14.71 0.0007
2018-02-14 2017-12-31 13F PACIFIC BIOSCIENCES CALIF IN COM 69404D108 1,204,926 -57,029 -4.52 3,181 -51.98 0.0008
2017-11-13 2017-09-30 13F PACIFIC BIOSCIENCES CALIF IN COM 69404D108 1,261,955 185,895 17.28 6,625 72.93 0.0017
2017-08-11 2017-06-30 13F PACIFIC BIOSCIENCES CALIF IN COM 69404D108 1,076,060 84,795 8.55 3,831 -25.25 0.0011
2017-05-12 2017-03-31 13F PACIFIC BIOSCIENCES CALIF IN COM 69404D108 991,265 28,744 2.99 5,125 40.10 0.0015
2017-02-13 2016-12-31 13F PACIFIC BIOSCIENCES CALIF IN COM 69404D108 962,521 29,097 3.12 3,658 -56.26 0.0011
2016-11-09 2016-09-30 13F PACIFIC BIOSCIENCES CALIF IN COM 69404D108 933,424 42,464 4.77 8,363 33.42 0.0026
2016-08-12 2016-06-30 13F PACIFIC BIOSCIENCES CALIF IN COM 69404D108 890,960 136,970 18.17 6,268 -2.20 0.0020
2016-08-19 2016-03-31 13F/A-1 PACIFIC BIOSCIENCES CALIF IN COM 69404D108 753,990 62,065 8.97 6,409 -29.46 0.0021
2016-05-13 2016-03-31 13F PACIFIC BIOSCIENCES CALIF IN COM 69404D108 753,990 6,409
2016-02-12 2015-12-31 13F PACIFIC BIOSCIENCES CALIF IN COM 69404D108 691,925 36,357 5.55 9,085 278.70 0.0030
2015-11-12 2015-09-30 13F PACIFIC BIOSCIENCES CALIF IN COM 69404D108 655,568 655,568 0.00 2,399 0.0008
2015-08-13 2015-06-30 13F PACIFIC BIOSCIENCES CALIF IN COM 69404D108 0 -615,537 -100.00 0 -100.00
2015-05-14 2015-03-31 13F PACIFIC BIOSCIENCES CALIF IN COM 69404D108 615,537 3,935 0.64 3,594 -25.05 0.0011
2015-02-12 2014-12-31 13F PACIFIC BIOSCIENCES CALIF IN COM 69404D108 611,602 -4,326 -0.70 4,795 58.56 0.0014
2014-11-13 2014-09-30 13F PACIFIC BIOSCIENCES CALIF IN COM 69404D108 615,928 58,078 10.41 3,024 -12.27 0.0009
2014-08-14 2014-06-30 13F PACIFIC BIOSCIENCES CALIF IN COM 69404D108 557,850 -35,647 -6.01 3,447 8.57 0.0011
2014-05-14 2014-03-31 13F PACIFIC BIOSCIENCES CALIF IN COM 69404D108 593,497 -46,751 -7.30 3,175 -5.17 0.0010
2014-02-21 2013-12-31 13F/A-1 PACIFIC BIOSCIENCES CALIF IN COM 69404D108 640,248 25,252 4.11 3,348 -1.38 0.0011
2014-02-12 2013-12-31 13F PACIFIC BIOSCIENCES CALIF IN COM 69404D108 640,248 3,348
2013-11-13 2013-09-30 13F PACIFIC BIOSCIENCES CALIF IN COM 69404D108 614,996 111,737 22.20 3,395 166.69 0.0012
2013-08-09 2013-06-30 13F PACIFIC BIOSCIENCES CALIF IN COM 69404D108 503,259 503,259 1,273 0.0005
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.