Arcus Biosciences, Inc.
US ˙ NYSE ˙ US03969F1093

SecurityRCUS / Arcus Biosciences, Inc.
InstitutionD. E. Shaw & Co., Inc.
ManagerDE Shaw
Latest Disclosed Ownership259,400 shares
Latest Disclosed Value $ 5,603,040
D. E. Shaw & Co., Inc. reports 203.14% increase in ownership of RCUS / Arcus Biosciences, Inc.

On May 15, 2026 - D. E. Shaw & Co., Inc. filed a 13F-HR form disclosing ownership of 259,400 shares of Arcus Biosciences, Inc. (US:RCUS) valued at $5,603,040 USD as of March 31, 2026. The entity filed a previous 13F-HR on February 17, 2026 disclosing 85,570 shares of Arcus Biosciences, Inc.. This represents a change in shares of 203.14% during the quarter. The current value of the position is $6,189,284 USD.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date
Effective
Date
Form Security Class ID Avg Price
Paid (Est)
Reported
Shares
ΔShares ΔShares
(%)
Reported
Value
(x1000)
ΔValue
(%)
Alloc
(%)
ΔAlloc ΔAlloc (%) Cost Basis
(x1000)
Unrealized
Gain/Loss
(x1000)
2026-05-15 2026-03-31 13F ARCUS BIOSCIENCES COM 03969F109 259,400 173,830 203.14 5,603 174.79 0.0034
2026-02-17 2025-12-31 13F ARCUS BIOSCIENCES COM 03969F109 85,570 65,699 330.63 2,039 655.19 0.0011
2025-11-14 2025-09-30 13F ARCUS BIOSCIENCES COM 03969F109 19,871 -31,453 -61.28 270 -35.25 0.0002
2025-08-14 2025-06-30 13F ARCUS BIOSCIENCES COM 03969F109 51,324 -4,717 -8.42 418 -5.01 0.0003
2025-05-15 2025-03-31 13F ARCUS BIOSCIENCES COM 03969F109 56,041 56,041 440 0.0004
2025-02-14 2024-12-31 13F ARCUS BIOSCIENCES COM 03969F109 0 -13,501 -100.00 0 -100.00
2024-11-14 2024-09-30 13F ARCUS BIOSCIENCES COM 03969F109 13,501 -17,264 -56.12 206 -55.98 0.0002
2024-08-14 2024-06-30 13F ARCUS BIOSCIENCES COM 03969F109 30,765 -36,777 -54.45 469 -63.29 0.0004
2024-05-15 2024-03-31 13F ARCUS BIOSCIENCES COM 03969F109 67,542 67,542 1,275 0.0011
2023-11-14 2023-09-30 13F ARCUS BIOSCIENCES COM 03969F109 0 -9,995 -100.00 0 -100.00
2023-08-14 2023-06-30 13F ARCUS BIOSCIENCES COM 03969F109 9,995 9,995 203 0.0002
2023-05-15 2023-03-31 13F ARCUS BIOSCIENCES COM 03969F109 0 -26,804 -100.00 0 -100.00
2023-02-14 2022-12-31 13F ARCUS BIOSCIENCES COM 03969F109 26,804 26,804 554 0.0006
2022-08-15 2022-06-30 13F ARCUS BIOSCIENCES COM 03969F109 0 -44,087 -100.00 0 -100.00
2022-05-16 2022-03-31 13F ARCUS BIOSCIENCES COM 03969F109 44,087 -288,907 -86.76 1,391 -89.68 0.0013
2022-02-14 2021-12-31 13F ARCUS BIOSCIENCES COM 03969F109 332,994 140,031 72.57 13,477 100.28 0.0112
2021-11-15 2021-09-30 13F ARCUS BIOSCIENCES COM 03969F109 192,963 -161,983 -45.64 6,729 -30.96 0.0061
2021-08-16 2021-06-30 13F ARCUS BIOSCIENCES COM 03969F109 354,946 -204,363 -36.54 9,746 -37.95 0.0084
2021-05-17 2021-03-31 13F ARCUS BIOSCIENCES COM 03969F109 559,309 -10,024 -1.76 15,706 6.27 0.0152
2021-02-16 2020-12-31 13F ARCUS BIOSCIENCES COM 03969F109 569,333 -44,704 -7.28 14,780 40.43 0.0132
2020-11-16 2020-09-30 13F ARCUS BIOSCIENCES COM 03969F109 614,037 168,755 37.90 10,525 -4.46 0.0108
2020-08-14 2020-06-30 13F ARCUS BIOSCIENCES COM 03969F109 445,282 445,282 11,016 0.0131
2020-05-15 2020-03-31 13F ARCUS BIOSCIENCES COM 03969F109 0 -33,100 -100.00 0 -100.00
2020-02-14 2019-12-31 13F ARCUS BIOSCIENCES COM 03969F109 33,100 33,100 334 0.0004
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.