Royalty Pharma plc
US ˙ NasdaqGS ˙ GB00BMVP7Y09

SecurityRPRX / Royalty Pharma plc
InstitutionSquarepoint Ops LLC
Latest Disclosed Ownership1,349,516 shares
Latest Disclosed Value $ 64,736,283
Squarepoint Ops LLC ownership in RPRX / Royalty Pharma plc

On May 15, 2026 - Squarepoint Ops LLC filed a 13F-HR form disclosing ownership of 1,349,516 shares of Royalty Pharma plc (US:RPRX) valued at $64,736,283 USD as of March 31, 2026. The entity filed a previous 13F-HR on February 13, 2026 disclosing 1,556,241 shares of Royalty Pharma plc. This represents a change in shares of -13.28% during the quarter. The current value of the position is $74,182,895 USD.

Squarepoint Ops LLC has a history of taking positions in derivatives of the underlying security (RPRX) in the form of stock options. The firm currently holds call options representing 0 of underlying shares valued at $0 USD .

Note: prior versions of this page mistakenly stated that the share values represented the number of options, not the number of underlying shares. For more information on the data backing these reports, please see the SEC document Frequently Asked Questions About Form 13F.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Institutional Put/Call Ratios
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In addition to reporting standard equity and debt issues, institutions with more than 100MM assets under management must also disclose their put and call option holdings. Since put options generally indicate negative sentiment, and call options indicate positive sentiment, we can get a sense of the overall institutional sentiment by plotting the ratio of puts to calls. The chart to the right plots the historical put/call ratio for this instrument.

Using Put/Call Ratio as an indicator of investor sentiment overcomes one of the key deficiencies of using total institutional ownership, which is that a significant amount of assets under management are invested passively to track indices. Passively-managed funds do not typically buy options, so the put/call ratio indicator more closely tracks the sentiment of actively-managed funds.

RPRX / Royalty Pharma plc Historical Put/Call Ratio
Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date
Effective
Date
Form Security Class ID Avg Price
Paid (Est)
Reported
Shares
ΔShares ΔShares
(%)
Reported
Value
(x1000)
ΔValue
(%)
Alloc
(%)
ΔAlloc ΔAlloc (%) Cost Basis
(x1000)
Unrealized
Gain/Loss
(x1000)
2026-05-15 2026-03-31 13F ROYALTY PHARMA SHS CLASS A G7709Q104 1,349,516 -206,725 -13.28 64,736 7.65 0.0761
2026-02-13 2025-12-31 13F ROYALTY PHARMA SHS CLASS A G7709Q104 1,556,241 870,454 126.93 60,133 148.55 0.0640
2025-11-14 2025-09-30 13F ROYALTY PHARMA SHS CLASS A G7709Q104 685,787 412,457 150.90 24,195 145.67 0.0243
2025-08-27 2025-06-30 13F/A-1 ROYALTY PHARMA SHS CLASS A G7709Q104 273,330 273,330 9,848 0.0102
2025-08-14 2025-06-30 13F ROYALTY PHARMA SHS CLASS A G7709Q104 273,330 273,330 9,848 0.0102
2025-08-27 2025-03-31 13F/A-1 ROYALTY PHARMA SHS CLASS A G7709Q104 0 -384,132 -100.00 0 -100.00
2025-05-15 2025-03-31 13F ROYALTY PHARMA SHS CLASS A G7709Q104 0 -384,132 0
2025-02-14 2024-12-31 13F ROYALTY PHARMA SHS CLASS A G7709Q104 384,132 -234,551 -37.91 9,799 -44.01 0.0097
2024-11-14 2024-09-30 13F ROYALTY PHARMA SHS CLASS A G7709Q104 618,683 217,157 54.08 17,503 65.30 0.0274
2024-08-14 2024-06-30 13F ROYALTY PHARMA SHS CLASS A G7709Q104 401,526 -222,513 -35.66 10,588 -44.13 0.0175
2024-05-15 2024-03-31 13F ROYALTY PHARMA SHS CLASS A G7709Q104 624,039 -276,855 -30.73 18,952 -25.11 0.0326
2024-02-14 2023-12-31 13F ROYALTY PHARMA SHS CLASS A G7709Q104 900,894 -55,662 -5.82 25,306 -2.52 0.0479
2023-11-14 2023-09-30 13F ROYALTY PHARMA SHS CLASS A G7709Q104 956,556 521,226 119.73 25,961 93.99 0.0641
2023-08-14 2023-06-30 13F ROYALTY PHARMA SHS CLASS A G7709Q104 435,330 -79,379 -15.42 13,382 -27.84 0.0410
2023-05-15 2023-03-31 13F ROYALTY PHARMA SHS CLASS A G7709Q104 514,709 227,440 79.17 18,545 63.35 0.0756
2023-02-14 2022-12-31 13F ROYALTY PHARMA SHS CLASS A G7709Q104 287,269 195,214 212.06 11,353 206.89 0.0449
2022-11-14 2022-09-30 13F ROYALTY PHARMA SHS CLASS A G7709Q104 92,055 -85,185 -48.06 3,699 -50.36 0.0187
2022-08-15 2022-06-30 13F ROYALTY PHARMA SHS CLASS A G7709Q104 177,240 -3,413 -1.89 7,451 5.87 0.0414
2022-05-16 2022-03-31 13F ROYALTY PHARMA SHS CLASS A G7709Q104 180,653 -188,375 -51.05 7,038 -52.14 0.0301
2022-02-14 2021-12-31 13F ROYALTY PHARMA SHS CLASS A G7709Q104 369,028 132,435 55.98 14,706 72.00 0.0389
2021-11-15 2021-09-30 13F ROYALTY PHARMA SHS CLASS A G7709Q104 236,593 60,441 34.31 8,550 18.42 0.0246
2021-08-16 2021-06-30 13F ROYALTY PHARMA SHS CLASS A G7709Q104 176,152 161,570 1,108.01 7,220 1,035.22 0.0275
2021-05-17 2021-03-31 13F ROYALTY PHARMA SHS CLASS A G7709Q104 14,582 -6,611 -31.19 636 -40.06 0.0037
2021-02-16 2020-12-31 13F ROYALTY PHARMA SHS CLASS A G7709Q104 21,193 21,193 1,061 0.0079
2020-11-16 2020-09-30 13F ROYALTY PHARMA SHS CL A G7709Q104 0 -200,000 -100.00 0 -100.00
2020-08-14 2020-06-30 13F ROYALTY PHARMA SHS CL A G7709Q104 200,000 200,000 9,710 0.1571
Disclosed Call Options
File
Date
Effective
Date
Form Security Class ID Opt Avg Share
Price
Shares ΔShares
(%)
Value
(x1000)
ΔValue
(%)
Prior Allocation
(%)
Allocation
(%)
ΔAllocation
(%)
Cost Basis
(x1000)
Profit
(x1000)
Return
(%)
2025-02-14 2024-12-31 13F ROYALTY PHARMA SHS CLASS A Call 0 -100.00 0 -100.00 n/a n/a n/a
2024-11-14 2024-09-30 13F ROYALTY PHARMA SHS CLASS A Call 7,500 212 n/a n/a n/a
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.